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Wyświetlanie 1-20 z 65
Podgląd okładki
Tytuł :
Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis
Index Terms :
Case-Control Studies
Cell Cycle Proteins/genetics
Cohort Studies
Genetic Predisposition to Disease
Genome-Wide Association Study
Homeodomain Proteins/genetics
Humans
Infant
Infant, Newborn
Microtubule-Associated Proteins/genetics
Neoplasm Proteins/genetics
Polymorphism, Single Nucleotide
Pyloric Stenosis, Hypertrophic/genetics
Serine Endopeptidases/genetics
Transcription Factors/genetics
dk/atira/pure/researchoutput/pubmedpublicationtype/D016428
Journal Article
dk/atira/pure/researchoutput/pubmedpublicationtype/D017418
Meta-Analysis
dk/atira/pure/researchoutput/pubmedpublicationtype/D052061
Research Support, N.I.H., Extramural
dk/atira/pure/researchoutput/pubmedpublicationtype/D013485
Research Support, Non-U.S. Gov't
article
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma:Increased Cell Migration and Its Association with EGFR Expression
Index Terms :
Adult
Aged
Cell Line, Tumor
Cell Movement/drug effects
Cell Proliferation/drug effects
Drug Resistance, Neoplasm/drug effects
Epithelial-Mesenchymal Transition/drug effects
ErbB Receptors/metabolism
Erlotinib Hydrochloride/pharmacology
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Inhibitory Concentration 50
Male
Melanoma/drug therapy
Middle Aged
Mutation/genetics
Neoplasm Proteins/genetics
Phenotype
Proto-Oncogene Proteins B-raf/genetics
RNA, Messenger/genetics
Signal Transduction/drug effects
Time Factors
Vemurafenib/pharmacology
dk/atira/pure/researchoutput/pubmedpublicationtype/D016428
Journal Article
article
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Shared heritability and functional enrichment across six solid cancers
Index Terms :
Breast Neoplasms/diagnosis
Case-Control Studies
Colorectal Neoplasms/diagnosis
European Continental Ancestry Group
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Head and Neck Neoplasms/diagnosis
Humans
Inheritance Patterns
Lung Neoplasms/diagnosis
Male
Mental Disorders/ethnology
Neoplasm Proteins/genetics
Ovarian Neoplasms/diagnosis
Phenotype
Polymorphism, Single Nucleotide
Prostatic Neoplasms/diagnosis
Smoking/ethnology
dk/atira/pure/researchoutput/pubmedpublicationtype/D016428
Journal Article
dk/atira/pure/researchoutput/pubmedpublicationtype/D052061
Research Support, N.I.H., Extramural
dk/atira/pure/researchoutput/pubmedpublicationtype/D013485
Research Support, Non-U.S. Gov't
article
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Predicting efficacy of epirubicin by a multigene assay in advanced breast cancer within a Danish Breast Cancer Cooperative Group (DBCG) cohort:a retrospective-prospective blinded study
Index Terms :
Adult
Aged
Biomarkers, Pharmacological
Breast Neoplasms/drug therapy
Disease Progression
Disease-Free Survival
Epirubicin/administration & dosage
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Middle Aged
Neoplasm Proteins/genetics
Precision Medicine
Proportional Hazards Models
Prospective Studies
RNA, Messenger/genetics
Retrospective Studies
dk/atira/pure/researchoutput/pubmedpublicationtype/D016428
Journal Article
article
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Index Terms :
Animals; Brain/metabolism; Carrier Proteins/genetics; Carrier Proteins/metabolism; Charcot-Marie-Tooth Disease/genetics; Charcot-Marie-Tooth Disease/metabolism; Consensus Sequence; Fibroblasts/metabolism; Gene Expression Regulation/physiology; HEK293 Cells; HSP27 Heat-Shock Proteins/genetics; HSP27 Heat-Shock Proteins/metabolism; HeLa Cells; Heat-Shock Proteins/genetics; Heat-Shock Proteins/metabolism; Heterogeneous-Nuclear Ribonucleoproteins/genetics; Heterogeneous-Nuclear Ribonucleoproteins/metabolism; Humans; Mice; Mutant Proteins/genetics; Mutant Proteins/metabolism; Mutation; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Protein Binding; Protein Biosynthesis/physiology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Untranslated Regions; Charcot-Marie-Tooth; Distal Hereditary Motor Neuropathy; HSPB1; PCBP1; RNA immunoprecipitation
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DDAA4510E51D5">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DDAA4510E51D5
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
A Multi-Method Approach for Proteomic Network Inference in 11 Human Cancers.
Index Terms :
Cluster Analysis; Databases, Protein; Gene Expression Profiling; Humans; Neoplasm Proteins/analysis; Neoplasm Proteins/genetics; Neoplasms/genetics; Neoplasms/metabolism; Principal Component Analysis; Protein Interaction Maps/physiology; Proteomics/methods; Software
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_143EFDA31CDA7">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_143EFDA31CDA7
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer.
Index Terms :
Recurrence Score
Neoadjuvant endocrine therapy
Ki-67
Clinical response
Breast-conserving surgery rate
Aged
Androstadienes/administration & dosage
Breast Neoplasms/drug therapy
Breast Neoplasms/genetics
Breast Neoplasms/pathology
Estrogen Receptor alpha/genetics
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Ki-67 Antigen/biosynthesis
Middle Aged
Neoplasm Proteins/biosynthesis
Neoplasm Proteins/genetics
Neoplasm Recurrence, Local/drug therapy
Neoplasm Recurrence, Local/genetics
Neoplasm Recurrence, Local/pathology
Neoplasm Staging
Receptor, ErbB-2/biosynthesis
Receptors, Progesterone/biosynthesis
Treatment Outcome
Journal Article
URL :
http://hdl.handle.net/2433/198719">http://hdl.handle.net/2433/198719
10.1007/s10147-013-0614-x
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.
Index Terms :
Animals; Cell Transformation, Neoplastic/genetics; Cell Transformation, Neoplastic/metabolism; Cluster Analysis; Colorectal Neoplasms/genetics; Colorectal Neoplasms/metabolism; Datasets as Topic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Mice; Mice, Knockout; Neoplasm Proteins/antagonists & inhibitors; Neoplasm Proteins/genetics; Neoplastic Stem Cells/metabolism; Phenotype; Prognosis; Sequence Deletion; Signal Transduction; Transcriptome; beta Catenin/antagonists & inhibitors; beta Catenin/genetics
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_CF71D7FE666E4">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_CF71D7FE666E4
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Interaction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer
Index Terms :
Antigens, CD/genetics; Antigens, CD/metabolism; Antineoplastic Agents/pharmacology; Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Carcinogenesis/genetics; Carcinogenesis/metabolism; Cell Adhesion Molecules/genetics; Cell Adhesion Molecules/metabolism; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Receptor, ErbB-2/genetics; Receptor, ErbB-2/metabolism; Trastuzumab/pharmacology; src-Family Kinases/metabolism
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4A7A9E6FDE414">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4A7A9E6FDE414
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.
Index Terms :
Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD14/genetics; CARD Signaling Adaptor Proteins/genetics; Child; Europe; Female; Genetic Predisposition to Disease/genetics; Genotype; Gout/genetics; Gout/immunology; Humans; Inflammasomes/genetics; Interleukin-1beta/genetics; Male; Middle Aged; Neoplasm Proteins/genetics; New Zealand; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Polynesia; Young Adult
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_29D3998119385">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_29D3998119385
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.
Index Terms :
ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Antigens, CD44/genetics; Antigens, CD44/metabolism; Biomarkers, Tumor/genetics; Biomarkers, Tumor/metabolism; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins/antagonists & inhibitors; DNA-Binding Proteins/genetics; Epithelial Cells/metabolism; Epithelial Cells/pathology; Epithelial-Mesenchymal Transition/genetics; Gene Expression Regulation, Neoplastic; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Humans; Isoenzymes/genetics; Isoenzymes/metabolism; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Neoplastic Stem Cells/metabolism; Neoplastic Stem Cells/pathology; Octamer Transcription Factor-3/genetics; Octamer Transcription Factor-3/metabolism; Organ Specificity; Phenotype; Polycomb Repressive Complex 1/genetics; Polycomb Repressive Complex 1/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Retinal Dehydrogenase/genetics; Retinal Dehydrogenase/metabolism; SOXB1 Transcription Factors/genetics; SOXB1 Transcription Factors/metabolism; Signal Transduction; Spheroids, Cellular/metabolism; Spheroids, Cellular/pathology; Telomerase/genetics; Telomerase/metabolism
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_127E6A07B81B0">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_127E6A07B81B0
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Emerging targeted agents in metastatic breast cancer
Index Terms :
Cancérologie
Antineoplastic Agents -- pharmacology
Breast Neoplasms -- drug therapy -- genetics -- secondary
Female
Humans
Molecular Targeted Therapy
Neoplasm Proteins -- genetics
Neoplastic Stem Cells -- drug effects
Tumor Microenvironment -- drug effects
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/183202">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/183202
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Expression of TMEM16A and SLC4A4 in human pancreatic islets.
Index Terms :
Diabétologie
Sciences biomédicales
Médecine pathologie humaine
Animals
Chloride Channels -- genetics -- metabolism
Gene Expression Regulation
Humans
Immunohistochemistry
Islets of Langerhans -- metabolism -- pathology
Mice
Neoplasm Proteins -- genetics -- metabolism
RNA, Messenger -- metabolism
Sodium-Bicarbonate Symporters -- genetics -- metabolism
Human
Islets
Pancreatic
SLC4A4
TMEM16A
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/132978">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/132978
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Genome-wide association meta-analysis identifies new endometriosis risk loci
Index Terms :
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Asian Continental Ancestry Group/genetics
Carrier Proteins/genetics
Chromosomes
Cohort Studies
Endometriosis/*genetics
European Continental Ancestry Group/genetics
Female
Human
Humans
Membrane Proteins/genetics
Neoplasm Proteins/genetics
Pair 1/genetics
Pair 2/genetics
Pair 6/genetics
Pair 7/genetics
Pair 9/genetics
Polymorphism
Risk
Severity of Illness Index
Single Nucleotide
Wnt4 Protein/genetics
Contribution to Journal
URL :
https://eprints.qut.edu.au/91839/1/emss-50444.pdf">https://eprints.qut.edu.au/91839/1/emss-50444.pdf
https://eprints.qut.edu.au/91839/1/emss-50444.pdf">https://eprints.qut.edu.au/91839/1/emss-50444.pdf
DOI:10.1038/ng.2445
Nyholt, Dale, Low, Siew-Kee, Anderson, Carl, Painter, Jodie, Uno, Satoko, Morris, Andrew, Macgregor, Stuart, Gordon, Scott, Henders, Anjali, Martin, Nicholas, & other, and (2012) Genome-wide association meta-analysis identifies new endometriosis risk loci. Nature Genetics, 44(12), pp. 1355-1359.
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta.
Index Terms :
Sciences biomédicales
Alleles
Computational Biology
DNA-Binding Proteins -- genetics
Female
Gene Expression
Genomic Imprinting
Humans
Microfilament Proteins -- genetics
Neoplasm Proteins -- genetics
Nerve Tissue Proteins -- genetics
Oligonucleotide Array Sequence Analysis
Placenta -- metabolism
Polymorphism, Single Nucleotide
Pregnancy
Sensitivity and Specificity
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/172692">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/172692
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours.
Index Terms :
Sciences bio-médicales et agricoles
Amino Acid Substitution -- genetics
Animals
Disease Models, Animal
Gastrointestinal Stromal Tumors -- enzymology
Gastrointestinal Stromal Tumors -- genetics
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Interstitial Cells of Cajal -- enzymology
Interstitial Cells of Cajal -- pathology
Membrane Glycoproteins -- genetics
Membrane Glycoproteins -- metabolism
Mice
Mutation -- genetics
Neoplasm Proteins -- genetics
Neoplasm Proteins -- metabolism
Nerve Tissue Proteins -- genetics
Nerve Tissue Proteins -- metabolism
Oligonucleotide Array Sequence Analysis
Proto-Oncogene Proteins c-kit -- genetics
Proto-Oncogene Proteins c-kit -- metabolism
Reproducibility of Results
Reverse Transcriptase Polymerase Chain Reaction
Up-Regulation -- genetics
Gastrointestinal stromal tumour
In vivo model
Interstitial cells of Cajal
KIT
Receptor tyrosine kinase
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51870">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51870
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.
Index Terms :
Sciences bio-médicales et agricoles
Antigens, CD137 -- metabolism
Antigens, CD70 -- genetics -- immunology
Antigens, Neoplasm -- genetics -- immunology
Cancer Vaccines -- genetics -- immunology
Cytokines -- metabolism
Dendritic Cells -- cytology -- immunology -- metabolism
Electroporation -- methods
Female
Flow Cytometry
Humans
Lysosomal-Associated Membrane Protein 1 -- metabolism
MART-1 Antigen
Male
Melanoma -- immunology -- pathology
Membrane Glycoproteins -- genetics -- immunology
Monophenol Monooxygenase -- genetics -- immunology
Neoplasm Proteins -- genetics -- immunology
Neoplasm Staging
RNA, Messenger -- genetics
Toll-Like Receptor 4 -- genetics -- immunology
Vaccination -- methods
gp100 Melanoma Antigen
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/123119">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/123119
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.
Index Terms :
Sciences bio-médicales et agricoles
Antigens, Neoplasm -- genetics -- immunology
CD4-Positive T-Lymphocytes -- immunology
Cancer Vaccines -- therapeutic use
Cell Line, Tumor
Clone Cells -- immunology
Flow Cytometry
Forkhead Transcription Factors -- genetics
Humans
Interleukin-2 -- pharmacology
Interleukin-4 -- pharmacology
Interleukin-7 -- pharmacology
Lymphocyte Activation -- drug effects
Melanoma -- immunology
Neoplasm Proteins -- genetics -- immunology
Peptide Fragments -- chemistry -- immunology
T-Lymphocytes -- immunology
T-Lymphocytes, Regulatory -- immunology
Vaccines, Subunit -- therapeutic use
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/123117">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/123117
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Wartość kliniczna oznaczania ekspresji epigenetycznie regulowanych białek u chorych na raka jajnika leczonych pochodnymi platyny
Index Terms :
medycyna
ovarian neoplasms - genetics
nowotwory jajników - genetyka
medicine
regulacja ekspresji genów w nowotworach
organoplatinum compounds - therapeutic use
DNA mismatch repair
nowotwory jajników - farmakoterapia
platynoorganiczne związki - stosowanie lecznicze
gene expression regulation, neoplastic
neoplasm proteins - genetics
naprawa DNA błędna
białka nowotworowe - genetyka
ovarian neoplasms - drug therapy
rozprawa doktorska
URL :
http://www.wbc.poznan.pl/Content/118713">http://www.wbc.poznan.pl/Content/118713
Zasób elektroniczny
Szczegóły
Wyświetlanie 1-20 z 65

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