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Wyszukujesz frazę ""Neoplasm Transplantation"" wg kryterium: Temat


Tytuł :
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice.
Autorzy :
Nowosielska EM; Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland.
Cheda A; Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland.
Pociegiel M; National Centre for Nuclear Research Radioisotope Centre POLATOM, 7A Soltana St., 05-400 Otwock, Poland.
Cheda L; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 101 Żwirki i Wigury St., 02-089 Warsaw, Poland.
Szymański P; Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland.; Department of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, 1 Muszyńskiego St., 90-151 Lodz, Poland.
Wiedlocha A; Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland.; Department of Molecular Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0379 Oslo, Norway.; Centre for Cancer Reprograming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Montebello, 0379 Oslo, Norway.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 11; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Transplantation*
Radiotherapy Dosage*
Whole-Body Irradiation*
Heat-Shock Proteins/*metabolism
Immune Checkpoint Proteins/*metabolism
Lung Neoplasms/*metabolism
Lung Neoplasms/*radiotherapy
Animals ; Clone Cells ; Lung/pathology ; Lymphocyte Count ; Lymphocytes, Tumor-Infiltrating ; Macrophages/pathology ; Mice, Inbred C57BL ; Tumor Stem Cell Assay
Czasopismo naukowe
Tytuł :
Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma.
Autorzy :
Kim Y; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan. .
Shiba-Ishii A; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.
Nakagawa T; Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.
Takeuchi T; Tsukuba Human Biobank Center, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba-shi, Ibaraki, 305-8576, Japan.
Kawai H; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.
Matsuoka R; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.
Noguchi M; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.
Sakamoto N; Department of Pathology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki, 305-8575, Japan.; Tsukuba Human Biobank Center, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba-shi, Ibaraki, 305-8576, Japan.
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Źródło :
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2021 May; Vol. 101 (5), pp. 543-553. Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Transplantation*
Carcinoma, Squamous Cell/*metabolism
Lung Neoplasms/*metabolism
Animals ; Antigens, CD19/metabolism ; Carcinoma, Squamous Cell/immunology ; Carcinoma, Squamous Cell/pathology ; Gene Expression Profiling ; Lung/pathology ; Lung Neoplasms/immunology ; Lung Neoplasms/pathology ; Mice, SCID ; Neoplasms, Experimental ; Receptors, IgE/metabolism
Czasopismo naukowe
Tytuł :
Tumor Allotransplantation in Drosophila melanogaster with a Programmable Auto-Nanoliter Injector.
Autorzy :
Gong S; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Zhang Y; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Bao H; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Wang X; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Chang CH; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Huang YC; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine.
Deng WM; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2021 Feb 02 (168). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Video-Audio Media
MeSH Terms :
Neoplasm Transplantation*
Allografts/*transplantation
Drosophila melanogaster/*physiology
Nanotechnology/*instrumentation
Neoplasms/*pathology
Abdomen/pathology ; Animals ; Dissection ; Injections ; Salivary Glands/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
A Method for the Establishment of Human Lung Adenocarcinoma Patient-Derived Xenografts in Mice.
Autorzy :
Lundy J; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.; Department of Surgery, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.
Jenkins BJ; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.
Saad MI; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia. .; Department of Molecular and Translational Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2279, pp. 165-173.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung*/metabolism
Adenocarcinoma of Lung*/pathology
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Neoplasm Transplantation*
Animals ; Female ; Heterografts ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID
Czasopismo naukowe
Tytuł :
Human T-ALL Xenografts.
Autorzy :
Fuentes P; Interactions with the Environment Program, Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.
Toribio ML; Interactions with the Environment Program, Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain. .
González-García S; Interactions with the Environment Program, Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2185, pp. 215-239.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasm Transplantation*
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/pathology
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/therapy
Animals ; Heterografts ; Humans ; Mice, SCID ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
In Vivo Imaging of Orthotopic Lung Cancer Models in Mice.
Autorzy :
Liu P; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France.; Sorbonne Université, Paris, France.; Université of Paris, Paris, France.
Zhao L; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France.; Sorbonne Université, Paris, France.; Université of Paris, Paris, France.; Université Paris-Saclay, Villejuif, France.
Senovilla L; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France. .; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France. .; Sorbonne Université, Paris, France. .; Université of Paris, Paris, France. .
Kepp O; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France. .; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France. .; Sorbonne Université, Paris, France. .; Université of Paris, Paris, France. .
Kroemer G; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France. .; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France. .; Sorbonne Université, Paris, France. .; Université of Paris, Paris, France. .; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China. .; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden. .; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2279, pp. 199-212.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Lewis Lung*/diagnostic imaging
Carcinoma, Lewis Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/diagnostic imaging
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/diagnostic imaging
Lung Neoplasms*/metabolism
Neoplasm Transplantation*
Optical Imaging*
Animals ; Humans ; Mice
Czasopismo naukowe
Tytuł :
An Experimental and Computational Protocol to Study Cell Proliferation in Human Acute Myeloid Leukemia Xenografts.
Autorzy :
Vlachou T; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy. .
Nobile MS; Department of Industrial Engineering and Innovation Sciences, Eindhoven University of Technology, Eindhoven, The Netherlands. .
Ronchini C; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy.
Besozzi D; Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy.
Pelicci PG; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2185, pp. 241-258.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Neoplasm Transplantation*
Neoplasms, Experimental*/metabolism
Neoplasms, Experimental*/pathology
Animals ; Female ; Heterografts ; Humans ; Male ; Mice ; Mice, Inbred NOD
Czasopismo naukowe
Tytuł :
Injured tissues favor cancer cell implantation via fibrin deposits on scar zones.
Autorzy :
Al Dybiat I; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France. Electronic address: .
Mirshahi S; Diagnostica Stago, 125 Avenue Louis Roche, 92230 Gennevilliers, France. Electronic address: .
Belalou M; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France.
Abdelhamid D; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France.
Shah S; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France.
Ullah M; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France.
Soria J; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France. Electronic address: .
Pocard M; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France. Electronic address: .
Mirshahi M; CAP-Paris Tech, INSERM U1275, Université de Paris, Lariboisière Hospital, 2 rue Ambroise Paré, 75010 Paris, France. Electronic address: .
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Źródło :
Neoplasia (New York, N.Y.) [Neoplasia] 2020 Dec; Vol. 22 (12), pp. 809-819. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Transplantation*/methods
Cicatrix/*metabolism
Fibrin/*metabolism
Animals ; Cell Adhesion ; Cell Culture Techniques ; Cell Line, Tumor ; Cicatrix/etiology ; Cicatrix/pathology ; Disease Models, Animal ; Female ; Fluorescent Antibody Technique ; Humans ; Mice ; Peritoneum/metabolism ; Peritoneum/pathology
Czasopismo naukowe
Tytuł :
The ongoing trends of patient-derived xenograft models in oncology.
Autorzy :
Zhuo J; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; National Health Commission Key Laboratory of Combined Multi-organ Transplantation, Institute of Organ Transplantation, Zhejiang University, Hangzhou, Zhejiang, 310003, P. R. China.
Su R; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; Department of Hepatobiliary and Pancreatic Surgery, Li Shui Hospital, Zhejiang University School of Medicine, Lishui, Zhejiang, 323000, P. R. China.
Tan W; Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.
Lian Z; National Health Commission Key Laboratory of Combined Multi-organ Transplantation, Institute of Organ Transplantation, Zhejiang University, Hangzhou, Zhejiang, 310003, P. R. China.
Lu D; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.
Xu X; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P. R. China.; National Health Commission Key Laboratory of Combined Multi-organ Transplantation, Institute of Organ Transplantation, Zhejiang University, Hangzhou, Zhejiang, 310003, P. R. China.
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Źródło :
Cancer communications (London, England) [Cancer Commun (Lond)] 2020 Nov; Vol. 40 (11), pp. 559-563. Date of Electronic Publication: 2020 Sep 20.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Medical Oncology*
Neoplasm Transplantation*
Animals ; Heterografts ; Humans
Raport
Tytuł :
IL26, a Noncanonical Mediator of DNA Inflammatory Stimulation, Promotes TNBC Engraftment and Progression in Association with Neutrophils.
Autorzy :
Trotter TN; Department of Surgery, Duke University, Durham, North Carolina.
Shuptrine CW; Department of Surgery, Duke University, Durham, North Carolina.
Tsao LC; Department of Surgery, Duke University, Durham, North Carolina.
Marek RD; Department of Pathology/Immunology, Duke University, Durham, North Carolina.
Acharya C; Department of Surgery, Duke University, Durham, North Carolina.
Wei JP; Department of Surgery, Duke University, Durham, North Carolina.
Yang XY; Department of Surgery, Duke University, Durham, North Carolina.
Lei G; Department of Surgery, Duke University, Durham, North Carolina.
Wang T; Department of Surgery, Duke University, Durham, North Carolina.
Lyerly HK; Department of Surgery, Duke University, Durham, North Carolina.
Hartman ZC; Department of Surgery, Duke University, Durham, North Carolina. .; Department of Pathology/Immunology, Duke University, Durham, North Carolina.
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Źródło :
Cancer research [Cancer Res] 2020 Aug 01; Vol. 80 (15), pp. 3088-3100. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Adhesion*/drug effects
Cell Adhesion*/genetics
Neoplasm Transplantation*/immunology
Neoplasm Transplantation*/pathology
Interleukins/*physiology
Neutrophils/*physiology
Triple Negative Breast Neoplasms/*pathology
Animals ; Cells, Cultured ; DNA, Neoplasm/drug effects ; DNA, Neoplasm/metabolism ; Disease Progression ; Extracellular Traps/drug effects ; Extracellular Traps/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Inflammation Mediators/pharmacology ; Inflammation Mediators/physiology ; Interleukins/genetics ; Interleukins/pharmacology ; Mice ; Mice, Inbred C57BL ; Mice, SCID ; Neutrophils/pathology ; Triple Negative Breast Neoplasms/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation.
Autorzy :
Toki S; Division of Genome Medicine, Advanced Institute of Medical Sciences, Tokushima University, Tokushima, Japan.; Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Yoshimaru T; Division of Genome Medicine, Advanced Institute of Medical Sciences, Tokushima University, Tokushima, Japan.
Matsushita Y; Division of Genome Medicine, Advanced Institute of Medical Sciences, Tokushima University, Tokushima, Japan.
Aihara H; Division of Genome Medicine, Advanced Institute of Medical Sciences, Tokushima University, Tokushima, Japan.
Ono M; Department of Proteomics, National Cancer Center Research Institute, Tokyo, Japan.
Tsuneyama K; Department of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Sairyo K; Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Katagiri T; Division of Genome Medicine, Advanced Institute of Medical Sciences, Tokushima University, Tokushima, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 4208-4219. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*pathology
Cell Proliferation/*physiology
Cell Survival/*physiology
Guanine Nucleotide Exchange Factors/*physiology
Mitochondria/*metabolism
Osteosarcoma/*pathology
Repressor Proteins/*physiology
Animals ; Apoptosis/physiology ; Apoptosis Inducing Factor/metabolism ; Bone Neoplasms/metabolism ; Bone Neoplasms/therapy ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell-Penetrating Peptides/pharmacology ; Databases, Factual ; Down-Regulation ; G2 Phase Cell Cycle Checkpoints ; Gene Silencing ; Guanine Nucleotide Exchange Factors/drug effects ; Guanine Nucleotide Exchange Factors/metabolism ; Humans ; M Phase Cell Cycle Checkpoints ; Membrane Proteins/metabolism ; Mice ; Mice, Nude ; Mitochondrial Membranes/metabolism ; Neoplasm Invasiveness ; Neoplasm Transplantation ; Osteosarcoma/metabolism ; Osteosarcoma/therapy ; Poly (ADP-Ribose) Polymerase-1/metabolism ; RNA, Small Interfering/metabolism ; Repressor Proteins/drug effects ; Repressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
Current progress and future perspectives of research on intravascular large B-cell lymphoma.
Autorzy :
Shimada K; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kiyoi H; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 3953-3961. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lymphoma, Large B-Cell, Diffuse*/diagnostic imaging
Lymphoma, Large B-Cell, Diffuse*/drug therapy
Lymphoma, Large B-Cell, Diffuse*/genetics
Lymphoma, Large B-Cell, Diffuse*/pathology
Vascular Neoplasms*/diagnostic imaging
Vascular Neoplasms*/drug therapy
Vascular Neoplasms*/genetics
Vascular Neoplasms*/pathology
Antimetabolites, Antineoplastic/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; B7-H1 Antigen/genetics ; Cell Cycle Checkpoints/genetics ; Central Nervous System Neoplasms/prevention & control ; Clinical Trials, Phase II as Topic ; Cyclophosphamide/therapeutic use ; Doxorubicin/therapeutic use ; Female ; Forecasting ; Heterografts ; Humans ; Injections, Spinal ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Neoplasm Transplantation ; Prednisone/therapeutic use ; Programmed Cell Death 1 Ligand 2 Protein/genetics ; Progression-Free Survival ; Rituximab/therapeutic use ; Vincristine/therapeutic use
Czasopismo naukowe
Tytuł :
TH1902, a new docetaxel-peptide conjugate for the treatment of sortilin-positive triple-negative breast cancer.
Autorzy :
Demeule M; Theratechnologies Inc., Montréal, QC, Canada.
Charfi C; Theratechnologies Inc., Montréal, QC, Canada.
Currie JC; Theratechnologies Inc., Montréal, QC, Canada.
Larocque A; Theratechnologies Inc., Montréal, QC, Canada.
Zgheib A; Laboratoire d'Oncologie Moléculaire, Université du Québec à Montréal, Montréal, QC, Canada.
Kozelko S; Laboratoire d'Oncologie Moléculaire, Université du Québec à Montréal, Montréal, QC, Canada.
Béliveau R; Laboratoire d'Oncologie Moléculaire, Université du Québec à Montréal, Montréal, QC, Canada.
Marsolais C; Theratechnologies Inc., Montréal, QC, Canada.
Annabi B; Laboratoire d'Oncologie Moléculaire, Université du Québec à Montréal, Montréal, QC, Canada.
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Źródło :
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 4317-4334. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Vesicular Transport/*metabolism
Triple Negative Breast Neoplasms/*drug therapy
Triple Negative Breast Neoplasms/*metabolism
Adaptor Proteins, Vesicular Transport/genetics ; Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Down-Regulation ; Drug Combinations ; Drug Discovery ; Female ; Gene Silencing ; Heterografts ; Humans ; Lymphatic Metastasis ; Mice ; Mice, Nude ; Microtubules/drug effects ; Neoplasm Transplantation ; Neurotensin/pharmacology ; Progranulins/pharmacology ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/pathology ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł :
[Establishment of human colon cancer transplantation tumor model in normal immune mice].
Autorzy :
Cheng SM; Jining Medical University Clinical Medical College, Jining 272000, China.
Liu JL; The First Affiliated Hospital of Hebei North University, Cancer Institute, Zhangjiakou 075000, China.
Chen T; Gastrointestinal Surgery, the Third Hospital of Jilin University, Changchun 130000, China.
Bi YZ; Department of Gastroenterology, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Liu KY; Jining Medical University Clinical Medical College, Jining 272000, China.
Wang QY; Department of Pathology, Affiliated Hospital of Jining Medical College, Jining 272000, China.
Tang HX; Jining Medical University Clinical Medical College, Jining 272000, China.
Yang YH; Central Laboratory, Affiliated Hospital of Jining Medical College, Jining 272000, China.
Zhang XB; Central Laboratory, Affiliated Hospital of Jining Medical College, Jining 272000, China.
Hu RR; Department of Gastroenterology, Affiliated Hospital of Jining Medical College, Jining 272000, China.
Liu SQ; Department of Gastroenterology, Affiliated Hospital of Jining Medical College, Jining 272000, China.
Zhang K; Department of Gastrointestinal Surgery, the Second Hospital of Jilin University, Changchun 130000, China.
Kong LB; Jining Medical University Clinical Medical College, Jining 272000, China.
Guo DL; Jining Medical University Clinical Medical College, Jining 272000, China.
Shu ZF; Shanghai Meifeng Biotechnology Co., Ltd, Shanghai 201203, China.
Hong F; Central Laboratory, Affiliated Hospital of Jining Medical College, Jining 272000, China.
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Źródło :
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2021 Sep 23; Vol. 43 (9), pp. 939-943.
Typ publikacji :
Journal Article
MeSH Terms :
Colonic Neoplasms*
Animals ; Cell Line, Tumor ; Humans ; Mice ; Mice, Inbred BALB C ; Neoplasm Transplantation ; Tumor Burden
Czasopismo naukowe
Tytuł :
The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation.
Autorzy :
Martin TD; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Patel RS; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Cook DR; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Choi MY; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Patil A; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Liang AC; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Li MZ; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Haigis KM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Elledge SJ; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Sep 17; Vol. 373 (6561), pp. 1327-1335. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenesis*
Gene Silencing*
Genes, Tumor Suppressor*
Immune Evasion*/genetics
Neoplasms, Experimental/*genetics
Neoplasms, Experimental/*immunology
Animals ; CRISPR-Cas Systems ; Cell Line, Tumor ; Chemokine CCL2/metabolism ; Female ; GTP-Binding Protein alpha Subunits, G12-G13/genetics ; GTP-Binding Protein alpha Subunits, G12-G13/metabolism ; Humans ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/immunology ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, SCID ; Neoplasm Transplantation ; Neoplasms, Experimental/pathology ; Selection, Genetic ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Proautoimmune Allele of Tyrosine Phosphatase, PTPN22, Enhances Tumor Immunity.
Autorzy :
Orozco RC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA.
Marquardt K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA.
Mowen K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA.
Sherman LA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 15; Vol. 207 (6), pp. 1662-1671. Date of Electronic Publication: 2021 Aug 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alleles*
Immunity*
Carcinoma, Lewis Lung/*enzymology
Carcinoma, Lewis Lung/*immunology
Melanoma, Experimental/*enzymology
Melanoma, Experimental/*immunology
Protein Tyrosine Phosphatase, Non-Receptor Type 22/*genetics
Skin Neoplasms/*enzymology
Skin Neoplasms/*immunology
Animals ; Carcinoma, Lewis Lung/pathology ; Cell Line, Tumor ; Female ; Lymphocytes, Tumor-Infiltrating/immunology ; Male ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neoplasm Transplantation/methods ; Phenotype ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Estrogen markedly reduces circulating low-density neutrophils and enhances pro-tumoral gene expression in neutrophil of tumour-bearing mice.
Autorzy :
Lim CL; NTU Institute for Health Technologies, Interdisciplinary Graduate School, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Lin VC; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Sep 11; Vol. 21 (1), pp. 1017. Date of Electronic Publication: 2021 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Estrogens/*pharmacology
Mammary Neoplasms, Animal/*blood
Neutrophils/*drug effects
Animals ; Apoptosis/drug effects ; Arginase/genetics ; Arginase/metabolism ; Biomarkers, Tumor/metabolism ; Bone Marrow Cells/cytology ; Centrifugation, Density Gradient ; Estrogens/administration & dosage ; Female ; Flow Cytometry ; Gene Expression/drug effects ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Mammary Glands, Animal ; Mice ; Mice, Inbred BALB C ; Neoplasm Transplantation ; Neutrophils/cytology ; Neutrophils/metabolism ; Ovariectomy/methods ; Parity ; Postpartum Period ; Time Factors ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Soluble Factors Involved in Cancer Cell-Macrophage Interaction Promote Breast Cancer Growth.
Autorzy :
Yonemitsu K; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Miyasato Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shiota T; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shinchi Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Fujiwara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Hosaka S; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Yamamoto Y; Department of Breast and Endocrine Surgery, Kumamoto University Hospital, Kumamoto, Japan.
Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; .; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4249-4258.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*pathology
Heparin-binding EGF-like Growth Factor/*genetics
Interleukin-6/*genetics
Macrophages/*cytology
Osteopontin/*genetics
Tumor-Associated Macrophages/*cytology
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Communication ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Female ; Heparin-binding EGF-like Growth Factor/metabolism ; Humans ; Interleukin-6/metabolism ; MCF-7 Cells ; Macrophages/metabolism ; Mice ; Neoplasm Transplantation ; Osteopontin/metabolism ; Tumor Microenvironment ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/pathology
Czasopismo naukowe
Tytuł :
Multimodal Intralesional Therapy for Reshaping the Myeloid Compartment of Tumors Resistant to Anti-PD-L1 Therapy via IRF8 Expression.
Autorzy :
Patel A; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Oba T; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Kajihara R; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Yokoi T; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY; and.
Ito F; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY; .; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY; and.; Department of Surgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 01; Vol. 207 (5), pp. 1298-1309. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells/*immunology
Immunotherapy/*methods
Interferon Regulatory Factors/*metabolism
Mammary Neoplasms, Animal/*therapy
Membrane Proteins/*therapeutic use
Myeloid-Derived Suppressor Cells/*immunology
T-Lymphocytes/*immunology
Animals ; B7-H1 Antigen ; Basic-Leucine Zipper Transcription Factors/genetics ; CD40 Antigens/metabolism ; Cell Line, Tumor ; Combined Modality Therapy ; Drug Resistance ; Gene Expression Regulation ; Humans ; Injections, Intralesional ; Interferon Regulatory Factors/genetics ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neoplasm Transplantation ; Radiotherapy ; Repressor Proteins/genetics ; Toll-Like Receptor 3/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells.
Autorzy :
Furuta T; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Oda T; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Kiyoi K; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Yusuke O; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Kimura S; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Kurimori K; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Miyazaki Y; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Yu Y; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Furuya K; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Akashi Y; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Shimomura O; Faculty of Medicine, Department of Surgery, Clinical Sciences, University of Tsukuba, Tsukuba, Japan.
Tateno H; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3722-3731. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoembryonic Antigen/*metabolism
Carcinoma, Pancreatic Ductal/*metabolism
Carrier Proteins/*metabolism
Lectins/*metabolism
Pancreatic Neoplasms/*metabolism
Animals ; Antibodies/immunology ; Carcinoembryonic Antigen/immunology ; Carcinoma, Pancreatic Ductal/pathology ; Cell Line, Tumor ; Female ; GPI-Linked Proteins/immunology ; GPI-Linked Proteins/metabolism ; Heterografts ; Humans ; Immunohistochemistry/methods ; Immunoprecipitation/methods ; Ligands ; Mice ; Mice, Inbred ICR ; Mice, SCID ; Neoplasm Transplantation ; Pancreatic Neoplasms/pathology
Czasopismo naukowe

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