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Wyszukujesz frazę ""Neoplastic Stem Cells"" wg kryterium: Temat


Tytuł :
MicroRNA Regulation of Breast Cancer Stemness.
Autorzy :
Humphries B; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA.
Wang Z; Division of Cancer Biology, Department of Medicine, MetroHealth Medical Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.
Yang C; Division of Cancer Biology, Department of Medicine, MetroHealth Medical Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 04; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Breast Neoplasms/*metabolism
MicroRNAs/*biosynthesis
Neoplastic Stem Cells/*metabolism
RNA, Neoplasm/*biosynthesis
Breast Neoplasms/pathology ; Female ; Humans ; Neoplastic Stem Cells/pathology
Czasopismo naukowe
Tytuł :
Breast cancer stem cells: A review of their characteristics and the agents that affect them.
Autorzy :
Shan NL; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.
Shin Y; Yonsei University, College of Medicine, Seoul, Republic of Korea.
Yang G; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.
Furmanski P; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
Suh N; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2021 Feb; Vol. 60 (2), pp. 73-100. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*genetics
Drug Resistance, Neoplasm/*genetics
Neoplastic Stem Cells/*metabolism
Signal Transduction/*genetics
Transcription Factors/*genetics
Antineoplastic Agents/therapeutic use ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Cell Self Renewal/genetics ; Drug Resistance, Neoplasm/drug effects ; Humans ; Molecular Targeted Therapy/methods ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/pathology ; Signal Transduction/drug effects ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients.
Autorzy :
Papadaki MA; Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece.
Aggouraki D; Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece.
Vetsika EK; Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece.
Xenidis N; Department of Medical Oncology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.; Hellenic Oncology Research Group (HORG), Athens, Greece.
Kallergi G; Hellenic Oncology Research Group (HORG), Athens, Greece.; Department of Biology, University of Patras, Patras, Greece.
Kotsakis A; Hellenic Oncology Research Group (HORG), Athens, Greece.; Department of Medical Oncology, University Hospital of Larissa & Laboratory of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Georgoulias V; Hellenic Oncology Research Group (HORG), Athens, Greece; .; School of Medicine, University of Crete, Heraklion, Greece.
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Źródło :
Anticancer research [Anticancer Res] 2021 Feb; Vol. 41 (2), pp. 661-670.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Epithelial-Mesenchymal Transition*
Tumor Escape*
Breast Neoplasms/*immunology
Myeloid-Derived Suppressor Cells/*immunology
Neoplastic Cells, Circulating/*immunology
Neoplastic Stem Cells/*immunology
T-Lymphocytes, Regulatory/*immunology
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Breast Neoplasms/blood ; Breast Neoplasms/pathology ; Case-Control Studies ; Female ; Flow Cytometry ; Humans ; Immunophenotyping ; Middle Aged ; Myeloid-Derived Suppressor Cells/metabolism ; Neoplastic Cells, Circulating/metabolism ; Neoplastic Cells, Circulating/pathology ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Phenotype ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe
Tytuł :
ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy.
Autorzy :
Dutta I; Department of Experimental Oncology, University of Alberta, Edmonton, AB, Canada.
Dieters-Castator D; Department of Anatomy and Cell Biology, Western University, London, ON, Canada.
Papatzimas JW; Department of Chemistry, University of Calgary, Calgary, AB, Canada.
Medina A; Department of Experimental Oncology, University of Alberta, Edmonton, AB, Canada.
Schueler J; Charles River Discovery Research Services Germany, Freiburg, Germany.
Derksen DJ; Department of Chemistry, University of Calgary, Calgary, AB, Canada.
Lajoie G; Department of Biochemistry, Western University, London, ON, Canada.
Postovit LM; Department of Experimental Oncology, University of Alberta, Edmonton, AB, Canada.
Siegers GM; Department of Experimental Oncology, University of Alberta, Edmonton, AB, Canada. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2021 Jan 01; Vol. 496, pp. 156-168. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy*
ADAM Proteins/*antagonists & inhibitors
Breast Neoplasms/*drug therapy
Drug Resistance, Neoplasm/*drug effects
Gene Expression Regulation, Neoplastic/*drug effects
Intraepithelial Lymphocytes/*immunology
Neoplastic Stem Cells/*drug effects
Protease Inhibitors/*pharmacology
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/immunology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Proliferation ; Female ; Humans ; Intraepithelial Lymphocytes/drug effects ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/immunology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Molecular Targeted Therapy ; Neoplastic Stem Cells/immunology ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells.
Autorzy :
Murayama T; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Takeuchi Y; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Yamawaki K; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.; Department of Obstetrics and Gynecology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Natsume T; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima City, Japan.; Department of Genetics, SOKENDAI, Mishima City, Japan.
Li M; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Marcela RN; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Nishimura T; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Kogure Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Science, The University of Tokyo, Kashiwa City, Japan.
Nakata A; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.; Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Tominaga K; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.
Sasahara A; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Department of Breast & Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Yano M; Department of Surgery, Minamimachida Hospital, Machida City, Japan.
Ishikawa S; Department of Gastroenterological Surgery, Kanazawa University, Kanazawa City, Japan.
Ohta T; Department of Gastroenterological Surgery, Kanazawa University, Kanazawa City, Japan.
Ikeda K; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Horie-Inoue K; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Inoue S; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Seki M; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Suzuki Y; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Sugano S; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Enomoto T; Department of Obstetrics and Gynecology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Tanabe M; Department of Breast & Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Tada KI; Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Kanemaki MT; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima City, Japan.; Department of Genetics, SOKENDAI, Mishima City, Japan.
Okamoto K; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.
Tojo A; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Gotoh N; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Mar; Vol. 112 (3), pp. 1209-1224. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*genetics
Minichromosome Maintenance Proteins/*metabolism
Neoplasm Recurrence, Local/*genetics
Neoplastic Stem Cells/*pathology
Proto-Oncogene Proteins c-myc/*metabolism
Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Breast/pathology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; DNA Damage/drug effects ; DNA Replication/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Female ; Humans ; Minichromosome Maintenance Proteins/genetics ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/prevention & control ; Neoplastic Stem Cells/drug effects ; Primary Cell Culture ; Proto-Oncogene Proteins c-myc/antagonists & inhibitors ; Spheroids, Cellular ; Tumor Cells, Cultured ; Up-Regulation
Czasopismo naukowe
Tytuł :
Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer.
Autorzy :
Berger K; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden.
Rhost S; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden.
Rafnsdóttir S; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden.; Present address: Department of Surgery, National University Hospital of Iceland, 13-A Hringbraut, Reykjavik, Iceland.
Hughes É; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden.
Magnusson Y; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden.
Ekholm M; Department of Oncology, Region Jönköping County, Jönköping, Sweden.; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.; Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden.
Stål O; Department of Oncology, Region Jönköping County, Jönköping, Sweden.; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Rydén L; Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden.
Landberg G; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Box 425, Medicinaregatan 1G, SE-13 90, Gothenburg, Sweden. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Feb 22; Vol. 21 (1), pp. 185. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Vesicular Transport/*metabolism
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Neoplastic Stem Cells/*metabolism
Progranulins/*metabolism
Tamoxifen/*therapeutic use
Adult ; Antineoplastic Agents, Hormonal/therapeutic use ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/drug therapy ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Neoplastic Stem Cells/pathology ; Prognosis ; Randomized Controlled Trials as Topic ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Tumor-associated macrophages-mediated CXCL8 infiltration enhances breast cancer metastasis: Suppression by Danirixin.
Autorzy :
Nie G; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Cao X; The Affiliated Hospital of Qingdao University, Library, Shandong 266000, China.
Mao Y; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Lv Z; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Lv M; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Wang Y; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Wang H; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China.
Liu C; Department of Breast Center, The Affiliated Hospital of Qingdao University, Shandong 266000, China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Jun; Vol. 95, pp. 107153. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Breast Neoplasms/*drug therapy
Interleukin-8/*immunology
Piperidines/*therapeutic use
Sulfones/*therapeutic use
Tumor-Associated Macrophages/*immunology
Animals ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/blood ; Breast Neoplasms/immunology ; Breast Neoplasms/pathology ; Cell Line ; Cell Movement/drug effects ; Epithelial-Mesenchymal Transition/drug effects ; Female ; Humans ; Interleukin-8/blood ; Mice, Inbred BALB C ; Mice, Nude ; Neoplastic Stem Cells/drug effects ; Piperidines/pharmacology ; Sulfones/pharmacology
Czasopismo naukowe
Tytuł :
Hyaluronic acid (HA)-coated naproxen-nanoparticles selectively target breast cancer stem cells through COX-independent pathways.
Autorzy :
Espinosa-Cano E; Biomaterials Group, Institute of Polymer Science and Technology (ICTP-CSIC), 28006 Madrid, Spain; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.
Huerta-Madroñal M; Biomaterials Group, Institute of Polymer Science and Technology (ICTP-CSIC), 28006 Madrid, Spain; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.
Cámara-Sánchez P; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain; Functional Validation & Preclinical Research (FVPR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain; Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Seras-Franzoso J; Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Schwartz S Jr; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain; Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Abasolo I; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain; Functional Validation & Preclinical Research (FVPR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain; Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. Electronic address: .
San Román J; Biomaterials Group, Institute of Polymer Science and Technology (ICTP-CSIC), 28006 Madrid, Spain; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.
Aguilar MR; Biomaterials Group, Institute of Polymer Science and Technology (ICTP-CSIC), 28006 Madrid, Spain; Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 May; Vol. 124, pp. 112024. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Breast Neoplasms*/drug therapy
Nanoparticles*
Cell Line, Tumor ; Endothelial Cells ; Glycogen Synthase Kinase 3 beta ; Humans ; Hyaluronan Receptors ; Hyaluronic Acid ; Naproxen/pharmacology ; Neoplastic Stem Cells
Czasopismo naukowe
Tytuł :
Drug Resistance in Metastatic Breast Cancer: Tumor Targeted Nanomedicine to the Rescue.
Autorzy :
Gote V; Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
Nookala AR; Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
Bolla PK; Department of Biomedical Engineering, College of Engineering, The University of Texas at El Paso, 500 W University Ave, El Paso, TX 79968, USA.; Department of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, High Point, NC 27268, USA.
Pal D; Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 28; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Breast Neoplasms/*drug therapy
Nanomedicine/*methods
Drug Delivery Systems ; Drug Resistance, Multiple/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Female ; Genetic Therapy/methods ; Humans ; Molecular Targeted Therapy ; Nanomedicine/trends ; Nanoparticles/therapeutic use ; Neoplasm Recurrence, Local/drug therapy ; Neoplastic Stem Cells/metabolism ; Precision Medicine ; Triple Negative Breast Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer.
Autorzy :
Cieśla M; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Ngoc PCT; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Cordero E; Division of Translational Cancer Research, Department of Laboratory Medicine, Faculty of Medicine, Lund University, 22363 Lund, Sweden.
Martinez ÁS; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Morsing M; Division of Translational Cancer Research, Department of Laboratory Medicine, Faculty of Medicine, Lund University, 22363 Lund, Sweden.
Muthukumar S; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Beneventi G; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Madej M; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Munita R; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Jönsson T; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Lövgren K; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Ebbesson A; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Nodin B; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Hedenfalk I; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Jirström K; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Vallon-Christersson J; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Honeth G; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Staaf J; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Incarnato D; Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.
Pietras K; Division of Translational Cancer Research, Department of Laboratory Medicine, Faculty of Medicine, Lund University, 22363 Lund, Sweden.
Bosch A; Division of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden. Electronic address: .
Bellodi C; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 22184 Lund, Sweden. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Apr 01; Vol. 81 (7), pp. 1453-1468.e12. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Breast Neoplasms/*metabolism
Carcinogenesis/*metabolism
Neoplastic Stem Cells/*metabolism
RNA Splicing Factors/*biosynthesis
Spliceosomes/*metabolism
Adult ; Aged ; Aged, 80 and over ; Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Carcinogenesis/genetics ; Female ; Humans ; Mice ; Mice, Nude ; Middle Aged ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; RNA Splicing Factors/genetics ; Spliceosomes/genetics
Czasopismo naukowe
Tytuł :
Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53.
Autorzy :
Ahn YT; Research Institute for Longevity and Well-Being, Pusan National University, Busan 46241, Korea.
Kim MS; Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.
Kim YS; Gene & Cell Therapy Research Center for Vessel-Associated Diseases, Pusan National University, Yangsan 50612, Korea.
An WG; Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.
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Źródło :
Marine drugs [Mar Drugs] 2020 Nov 20; Vol. 18 (11). Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
ATPases Associated with Diverse Cellular Activities/*metabolism
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Carrier Proteins/*metabolism
DNA Helicases/*metabolism
Neoplastic Stem Cells/*drug effects
Tumor Suppressor Protein p53/*metabolism
ATPases Associated with Diverse Cellular Activities/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carrier Proteins/genetics ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; DNA Helicases/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Mutation ; Nanog Homeobox Protein/genetics ; Nanog Homeobox Protein/metabolism ; Neoplasm Invasiveness ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Octamer Transcription Factor-3/genetics ; Octamer Transcription Factor-3/metabolism ; Tumor Suppressor Protein p53/genetics ; Xanthophylls/pharmacology
Czasopismo naukowe
Tytuł :
Breast Cancer Stem Cell Potency of Nickel(II)-Polypyridyl Complexes Containing Non-steroidal Anti-inflammatory Drugs.
Autorzy :
Feld CJ; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK.
Johnson A; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK.
Xiao Z; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK.
Suntharalingam K; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Nov 02; Vol. 26 (61), pp. 14011-14017. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Coordination Complexes*/chemistry
Coordination Complexes*/pharmacology
Neoplastic Stem Cells*/drug effects
Neoplastic Stem Cells*/pathology
Nickel*/chemistry
Female ; Humans
Czasopismo naukowe
Tytuł :
Coriolic Acid (13-( S )-Hydroxy-9 Z , 11 E -octadecadienoic Acid) from Glasswort ( Salicornia herbacea L.) Suppresses Breast Cancer Stem Cell through the Regulation of c-Myc.
Autorzy :
Ko YC; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Korea.
Choi HS; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.
Kim JH; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Korea.
Kim SL; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Korea.
Yun BS; Division of Biotechnology, College of Environmental and Bioresource Sciences, Chonbuk National University, Gobong-ro 79, Iksan 54596, Korea.
Lee DS; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Korea.; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.; Practical Translational Research Center, Jeju National University, Jeju 63243, Korea.; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 26; Vol. 25 (21). Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*pathology
Chenopodiaceae/*chemistry
Fatty Acids, Unsaturated/*chemistry
Fatty Acids, Unsaturated/*pharmacology
Neoplastic Stem Cells/*drug effects
Proto-Oncogene Proteins c-myc/*metabolism
Apoptosis/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology
Czasopismo naukowe
Tytuł :
MiR-375 inhibits the stemness of breast cancer cells by blocking the JAK2/STAT3 signaling.
Autorzy :
Zhao Q; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Liu Y; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Wang T; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Yang Y; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Ni H; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Liu H; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China.
Guo Q; Department of Pharmacy, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, 127 Dongming Road, Zhengzhou, 450003, PR China.
Xi T; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China. Electronic address: .
Zheng L; School of Life Science and Technology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Longmian Road 639, Nanjing, 211198, PR China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2020 Oct 05; Vol. 884, pp. 173359. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*enzymology
Janus Kinase 2/*metabolism
MicroRNAs/*metabolism
Neoplastic Stem Cells/*enzymology
STAT3 Transcription Factor/*metabolism
3' Untranslated Regions ; Antibiotics, Antineoplastic/pharmacology ; Binding Sites ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Doxorubicin/pharmacology ; Drug Resistance, Neoplasm ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Janus Kinase 2/genetics ; MCF-7 Cells ; MicroRNAs/genetics ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/pathology ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Typhonium flagelliforme extract induce apoptosis in breast cancer stem cells by suppressing survivin.
Autorzy :
Putra A; Biomedical Science Doctoral Program, Medical Faculty, Diponegoro University; Stem Cell and Cancer Research Laboratory, Medical Faculty, Sultan Agung Islamic University, Semarang, Indonesia.
Riwanto I; Department of Surgery, Medical Faculty, Diponegoro University, Semarang, Indonesia.
Putra ST; Department of Pathobiology, Medical Faculty, Airlangga University, Surabaya, Indonesia.
Wijaya I; Department of Anatomical Pathology, Medical Faculty, Diponegoro University, Semarang, Indonesia.
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Źródło :
Journal of cancer research and therapeutics [J Cancer Res Ther] 2020 Oct-Dec; Vol. 16 (6), pp. 1302-1308.
Typ publikacji :
Journal Article
MeSH Terms :
Araceae/*chemistry
Breast Neoplasms/*drug therapy
Neoplastic Stem Cells/*drug effects
Plant Extracts/*pharmacology
Survivin/*antagonists & inhibitors
Apoptosis/physiology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Caspase 3/metabolism ; Cell Line, Tumor ; Female ; Humans ; Hyaluronan Receptors/metabolism ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Survivin/metabolism
Czasopismo naukowe
Tytuł :
The Chick Chorioallantoic Membrane Model: A New In Vivo Tool to Evaluate Breast Cancer Stem Cell Activity.
Autorzy :
Pinto MT; i3S-Institute of Investigation and Innovation in Health, 4200-135 Porto, Portugal.; Ipatimup, Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.
Ribeiro AS; i3S-Institute of Investigation and Innovation in Health, 4200-135 Porto, Portugal.; Ipatimup, Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.
Conde I; i3S-Institute of Investigation and Innovation in Health, 4200-135 Porto, Portugal.; Ipatimup, Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.
Carvalho R; i3S-Institute of Investigation and Innovation in Health, 4200-135 Porto, Portugal.; Ipatimup, Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.
Paredes J; i3S-Institute of Investigation and Innovation in Health, 4200-135 Porto, Portugal.; Ipatimup, Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.; Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 30; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Chorioallantoic Membrane*
Breast Neoplasms/*pathology
Neoplastic Stem Cells/*pathology
Animals ; Apoptosis ; Breast Neoplasms/metabolism ; Cell Movement ; Cell Proliferation ; Chick Embryo ; Female ; Humans ; Hyaluronan Receptors/metabolism ; Mice ; Mice, Nude ; Neoplastic Stem Cells/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-Dependent YAP Pathway.
Autorzy :
Kim SL; Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, Jeju 63243, Korea.; Practical Translational Research Center, Jeju National University, Jeju 63243, Korea.; Bio-Health Materials Core-Facility Center, Jeju National University, Jeju 63243, Korea.; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Korea.; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.
Choi HS; Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, Jeju 63243, Korea.; Practical Translational Research Center, Jeju National University, Jeju 63243, Korea.; Bio-Health Materials Core-Facility Center, Jeju National University, Jeju 63243, Korea.; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Korea.; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.
Kim JH; Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, Jeju 63243, Korea.; Practical Translational Research Center, Jeju National University, Jeju 63243, Korea.; Bio-Health Materials Core-Facility Center, Jeju National University, Jeju 63243, Korea.; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Korea.; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.
Lee DS; Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, Jeju 63243, Korea.; Practical Translational Research Center, Jeju National University, Jeju 63243, Korea.; Bio-Health Materials Core-Facility Center, Jeju National University, Jeju 63243, Korea.; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Korea.; Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 19; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing/*metabolism
Anti-Asthmatic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Neoplastic Stem Cells/*drug effects
Pregnenediones/*pharmacology
Receptors, Glucocorticoid/*metabolism
Signal Transduction/*drug effects
Transcription Factors/*metabolism
Breast Neoplasms/metabolism ; Cell Line, Tumor ; Connective Tissue Growth Factor/metabolism ; Cysteine-Rich Protein 61/metabolism ; Glucocorticoids/metabolism ; Humans ; MCF-7 Cells ; Neoplastic Stem Cells/metabolism ; Protein-Serine-Threonine Kinases/metabolism ; RNA, Small Interfering/metabolism ; Verteporfin/metabolism
Czasopismo naukowe
Tytuł :
Cell Fusion of Mesenchymal Stem/Stromal Cells and Breast Cancer Cells Leads to the Formation of Hybrid Cells Exhibiting Diverse and Individual (Stem Cell) Characteristics.
Autorzy :
Dörnen J; Center for Biomedical Education and Research (ZBAF), Institute of Immunology, Witten/Herdecke University, Stockumer Str. 10, 58448 Witten, Germany.
Myklebost O; Department of Clinical Science, University of Bergen, Postboks 7804, 5020 Bergen, Norway.
Dittmar T; Center for Biomedical Education and Research (ZBAF), Institute of Immunology, Witten/Herdecke University, Stockumer Str. 10, 58448 Witten, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 17; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Fusion*
Epithelial-Mesenchymal Transition*
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*pathology
Hybrid Cells/*pathology
Mesenchymal Stem Cells/*pathology
Neoplastic Stem Cells/*pathology
Apoptosis ; Breast Neoplasms/metabolism ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Hybrid Cells/metabolism ; Mesenchymal Stem Cells/metabolism ; Neoplastic Stem Cells/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Partial acquisition of stemness properties in tumorspheres obtained from interleukin-8-treated MCF-7 cells.
Autorzy :
Ospina-Muñoz N; Cellular and Molecular Physiology Group, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, DC, Colombia.
Vernot JP; Cellular and Molecular Physiology Group, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, DC, Colombia.; Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, DC, Colombia.
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Źródło :
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine [Tumour Biol] 2020 Dec; Vol. 42 (12), pp. 1010428320979438.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*
Antibiotics, Antineoplastic/*pharmacology
Breast Neoplasms/*drug therapy
Doxorubicin/*pharmacology
Interleukin-8/*pharmacology
Neoplastic Stem Cells/*pathology
Spheroids, Cellular/*pathology
Apoptosis ; Breast Neoplasms/pathology ; Cell Proliferation ; Female ; Humans ; Neoplastic Stem Cells/drug effects ; Spheroids, Cellular/drug effects ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Upregulation of S100A10 in metastasized breast cancer stem cells.
Autorzy :
Yanagi H; Department of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.; Department of Medical Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Watanabe T; Department of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.
Nishimura T; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Hayashi T; Department of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.
Kono S; Division of Breast and Endocrine Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Tsuchida H; Division of Molecular and Cellular Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
Hirata M; Department of Breast Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
Kijima Y; Department of Breast Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
Takao S; Division of Breast and Endocrine Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Okada S; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
Suzuki M; Department of Molecular Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Imaizumi K; Department of Respiratory Medicine, Fujita Health University School of Medicine, Fujita Health University School of Medicine, Toyoake, Japan.
Kawada K; Department of Medical Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Minami H; Division of Medical Oncology/Hematology, Kobe University Graduate School of Medicine, Kobe, Japan.
Gotoh N; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Shimono Y; Department of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.; Division of Molecular and Cellular Biology, Kobe University Graduate School of Medicine, Kobe, Japan.; Division of Medical Oncology/Hematology, Kobe University Graduate School of Medicine, Kobe, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Dec; Vol. 111 (12), pp. 4359-4370. Date of Electronic Publication: 2020 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Annexin A2/*metabolism
Breast Neoplasms/*metabolism
Neoplastic Stem Cells/*metabolism
S100 Proteins/*metabolism
Animals ; Annexin A2/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Disease Progression ; Female ; Gene Expression Profiling ; Gene Knockout Techniques ; Humans ; Hyaluronan Receptors/metabolism ; Lentivirus/genetics ; Liver Neoplasms/pathology ; Liver Neoplasms/secondary ; Matrix Metalloproteinases/metabolism ; Mice ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Neoplastic Stem Cells/pathology ; Organoids ; Reverse Transcriptase Polymerase Chain Reaction ; S100 Proteins/genetics
Czasopismo naukowe

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