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Tytuł :
Expression and Clinical Significance of Neuropilin-1 in Patients With Multiple Myeloma.
Autorzy :
Karczmarczyk A; Department of Experimental Hematooncology, Medical University of Lublin, Lublin, Poland.
Bilska S; Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland.
Korpysz M; Department of Biochemical Diagnostics, Medical University of Lublin, Lublin, Poland.
Purkot J; Department of Experimental Hematooncology, Medical University of Lublin, Lublin, Poland.
GrzĄŚko N; Department of Experimental Hematooncology, Medical University of Lublin, Lublin, Poland.; Department of Hematology, St. John's Cancer Center, Lublin, Poland.
Hus M; Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland.
Giannopoulos K; Department of Experimental Hematooncology, Medical University of Lublin, Lublin, Poland .; Department of Hematology, St. John's Cancer Center, Lublin, Poland.
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Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5437-5443.
Typ publikacji :
Journal Article
MeSH Terms :
Multiple Myeloma/*genetics
Neovascularization, Pathologic/*genetics
Neuropilin-1/*genetics
Vascular Endothelial Growth Factor A/*genetics
Adult ; B-Lymphocytes/metabolism ; Female ; Flow Cytometry ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Male ; Middle Aged ; Multiple Myeloma/blood ; Multiple Myeloma/pathology ; Neovascularization, Pathologic/blood ; Neovascularization, Pathologic/pathology ; Neuropilin-1/blood ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Anti-angiogenesis: Opening a new window for immunotherapy.
Autorzy :
Guo F; Cancer Center, The First Hospital of Jilin University, Changchun 130021, China.
Cui J; Cancer Center, The First Hospital of Jilin University, Changchun 130021, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118163. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Immunotherapy/*methods
Neoplasms/*therapy
Neovascularization, Pathologic/*therapy
Animals ; Combined Modality Therapy ; Humans ; Neoplasms/complications ; Neoplasms/immunology ; Neoplasms/pathology ; Neovascularization, Pathologic/complications ; Neovascularization, Pathologic/immunology ; Neovascularization, Pathologic/pathology ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
The histone deacetylase HDAC1 activates HIF1α/VEGFA signal pathway in colorectal cancer.
Autorzy :
Chen C; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Wei M; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Wang C; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Sun D; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Liu P; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Zhong X; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
He Q; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China.
Yu W; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Sep 05; Vol. 754, pp. 144851. Date of Electronic Publication: 2020 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*pathology
Histone Deacetylase 1/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Neovascularization, Pathologic/*pathology
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Apoptosis ; Biomarkers, Tumor ; Cell Cycle ; Cell Movement ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Disease Progression ; Histone Deacetylase 1/genetics ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Male ; Mice ; Mice, Nude ; Neoplasm Invasiveness ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Prognosis ; Signal Transduction ; Tumor Cells, Cultured ; Vascular Endothelial Growth Factor A/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Anti-angiogenesis therapy overcomes the innate resistance to PD-1/PD-L1 blockade in VEGFA-overexpressed mouse tumor models.
Autorzy :
Wang Q; Department of Obstetrics and Gynecology, School of Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, 200127, People's Republic of China.; Shanghai Key Laboratory of Gynecologic Oncology, Shanghai, 200127, People's Republic of China.
Gao J; Department of Obstetrics and Gynecology, School of Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, 200127, People's Republic of China.; Shanghai Key Laboratory of Gynecologic Oncology, Shanghai, 200127, People's Republic of China.
Di W; Department of Obstetrics and Gynecology, School of Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, 200127, People's Republic of China.; Shanghai Key Laboratory of Gynecologic Oncology, Shanghai, 200127, People's Republic of China.
Wu X; Department of Obstetrics and Gynecology, School of Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, 200127, People's Republic of China. .; Shanghai Key Laboratory of Gynecologic Oncology, Shanghai, 200127, People's Republic of China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Sep; Vol. 69 (9), pp. 1781-1799. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
B7-H1 Antigen/*metabolism
Immunity, Innate/*immunology
Neoplasms/*metabolism
Neovascularization, Pathologic/*immunology
Neovascularization, Pathologic/*metabolism
Programmed Cell Death 1 Receptor/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Female ; Humans ; Immunity, Innate/drug effects ; Immunohistochemistry/methods ; Immunotherapy/methods ; Mice ; Mice, Inbred BALB C ; Neoplasms/immunology ; Neoplasms/therapy ; Neovascularization, Pathologic/drug therapy ; Prognosis ; Pyridines/pharmacology ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis.
Autorzy :
Hultgren NW; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Fang JS; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Ziegler ME; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Ramirez RN; The Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, 92697, USA.
Phan DTT; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Hatch MMS; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Welch-Reardon KM; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Paniagua AE; The Department of Ophthalmology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Kim LS; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Shon NN; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Williams DS; The Department of Ophthalmology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Mortazavi A; The Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, 92697, USA.
Hughes CCW; The Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA. .; The Department of Biomedical Engineering, University of California Irvine, Irvine, CA, 92697, USA. .; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California Irvine, Irvine, CA, 92697, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 26; Vol. 11 (1), pp. 5400. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing/*metabolism
Calcium-Binding Proteins/*metabolism
Endothelial Cells/*metabolism
Neovascularization, Pathologic/*metabolism
Snail Family Transcription Factors/*metabolism
Vascular Endothelial Growth Factor Receptor-2/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Calcium-Binding Proteins/genetics ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neovascularization, Pathologic/genetics ; Receptors, Notch/genetics ; Receptors, Notch/metabolism ; Signal Transduction ; Snail Family Transcription Factors/genetics ; Vascular Endothelial Growth Factor Receptor-2/genetics
Czasopismo naukowe
Tytuł :
Intussusceptive angiogenesis in Covid-19: hypothesis on the significance and focus on the possible role of FGF2.
Autorzy :
Meini S; Internal Medicine Unit, Santa Maria Annunziata Hospital, Florence, Italy. .
Giani T; Microbiology and Virology Unit, Careggi Hospital, University of Florence, ‎Florence, Italy.
Tascini C; Infectious Diseases Clinic, Santa Maria Misericordia Hospital, University of Udine, Udine, Italy.
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Źródło :
Molecular biology reports [Mol Biol Rep] 2020 Oct; Vol. 47 (10), pp. 8301-8304. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*pathology
Fibroblast Growth Factor 2/*metabolism
Neovascularization, Pathologic/*virology
Pneumonia, Viral/*pathology
Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Coronavirus Infections/drug therapy ; Coronavirus Infections/etiology ; Drug Delivery Systems ; Fibroblast Growth Factor 2/antagonists & inhibitors ; Humans ; Intussusception/virology ; Neovascularization, Pathologic/genetics ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/etiology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Non-coding RNAs regulate angiogenic processes.
Autorzy :
Ghafouri-Fard S; Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shoorei H; Department of Anatomical Sciences, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Mohaqiq M; Wake Forest Institute for Regenerative Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC, USA.
Taheri M; Urogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2020 Oct - Nov; Vol. 133-134, pp. 106778. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neovascularization, Pathologic*/genetics
Neovascularization, Physiologic*/genetics
Endothelial Cells/*metabolism
MicroRNAs/*metabolism
Neoplasms/*blood supply
Neoplasms/*metabolism
RNA, Long Noncoding/*metabolism
Animals ; Endothelial Cells/pathology ; Gene Expression Regulation ; Humans ; MicroRNAs/genetics ; Neoplasms/genetics ; Neoplasms/pathology ; RNA, Long Noncoding/genetics ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Promotion of Chondrosarcoma Cell Survival, Migration and Lymphangiogenesis by Periostin.
Autorzy :
Jeong JY; Department of Pathology, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
Jeong W; Department of Orthopedic Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
Kim HJ; Department of Physiology, Kyungpook National University, School of Medicine, Daegu, Republic of Korea .; BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Science, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
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Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5463-5469.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Adhesion Molecules/*genetics
Cell Proliferation/*genetics
Chondrosarcoma/*genetics
Neovascularization, Pathologic/*genetics
Cell Line, Tumor ; Cell Movement/genetics ; Cell Survival/genetics ; Chondrosarcoma/pathology ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Humans ; Lymphangiogenesis/genetics ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Neovascularization, Pathologic/pathology ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Imaging neoangiogenesis in rheumatoid arthritis (INIRA): whole-body synovial uptake of a Tc-labelled RGD peptide is highly correlated with power Doppler ultrasound.
Autorzy :
Attipoe L; Academic Department of Rheumatology, King's College London, London, UK .; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Chaabo K; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Wajed J; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Hassan FU; Nuclear Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Shivapatham D; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Morrison M; GE Healthcare Diagnostic Imaging, Little Chalfont, Buckinghamshire, UK.
Ballinger J; Nuclear Medicine, King's College London, London, UK.
Cook G; Cancer Imaging, King's College London, London, UK.
Cope AP; Academic Department of Rheumatology, King's College London, London, UK.; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Garrood T; Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2020 Sep; Vol. 79 (9), pp. 1254-1255. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Letter
MeSH Terms :
Arthritis, Rheumatoid/*diagnostic imaging
Neovascularization, Pathologic/*diagnostic imaging
Oligopeptides/*pharmacokinetics
Organotechnetium Compounds/*pharmacokinetics
Synovial Membrane/*blood supply
Ultrasonography, Doppler/*statistics & numerical data
Arthritis, Rheumatoid/complications ; Female ; Humans ; Male ; Middle Aged ; Neovascularization, Pathologic/etiology ; Proof of Concept Study ; Radioactive Tracers ; Reproducibility of Results ; Synovial Membrane/diagnostic imaging ; Ultrasonography, Doppler/methods
Opinia redakcyjna
Tytuł :
Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.
Autorzy :
Sun M; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
Deng R; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
Wang Y; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
Wu H; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China. Electronic address: .
Zhang Z; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
Bu Y; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
Zhang H; College of Pharmacy, Anhui University of Chinese Medicine, Qian Jiang Road 1, Hefei 230012, China; Key Laboratory of Xin'an Medicine, Ministry of Education, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, China.
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Źródło :
Life sciences [Life Sci] 2020 Sep 01; Vol. 256, pp. 117988. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems/*methods
Iridoids/*administration & dosage
Lysophospholipids/*metabolism
Neovascularization, Pathologic/*metabolism
Phosphotransferases (Alcohol Group Acceptor)/*metabolism
Sphingosine/*analogs & derivatives
Sphingosine-1-Phosphate Receptors/*metabolism
Animals ; Cell Survival/drug effects ; Cell Survival/physiology ; Cells, Cultured ; Lysophospholipids/antagonists & inhibitors ; Male ; Neovascularization, Pathologic/drug therapy ; Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Sphingosine/antagonists & inhibitors ; Sphingosine/metabolism ; Sphingosine-1-Phosphate Receptors/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Spectral CT in Lung Cancer: Usefulness of Iodine Concentration for Evaluation of Tumor Angiogenesis and Prognosis.
Autorzy :
Li Q; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Rd, Yuzhong District, Chongqing 400016, China.
Li X; Department of Pathology, Chongqing Medical University, Chongqing, China.
Li XY; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Rd, Yuzhong District, Chongqing 400016, China.
Huo JW; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Rd, Yuzhong District, Chongqing 400016, China.
Lv FJ; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Rd, Yuzhong District, Chongqing 400016, China.
Luo TY; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Rd, Yuzhong District, Chongqing 400016, China.
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Źródło :
AJR. American journal of roentgenology [AJR Am J Roentgenol] 2020 Sep; Vol. 215 (3), pp. 595-602. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lung Neoplasms/*diagnostic imaging
Neovascularization, Pathologic/*diagnostic imaging
Tomography, X-Ray Computed/*methods
Adult ; Aged ; Aged, 80 and over ; Contrast Media ; Female ; Humans ; Iohexol ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neovascularization, Pathologic/pathology ; Prognosis ; Prospective Studies ; Tumor Burden
Czasopismo naukowe
Tytuł :
Preliminary study of icariin indicating prevention of steroid-induced osteonecrosis of femoral head by regulating abnormal expression of miRNA-335 and protecting the functions of bone microvascular endothelial cells in rats.
Autorzy :
Yue J; Department of Orthopaedic, Aviation General Hospital, Courtyard 3, Anwai Beiyuan, Chaoyang District, Beijing, China. Electronic address: .
Yu H; Graduate School of Peking Union Medical College, Yinghuadong Road, Chaoyang District, Beijing , China. Electronic address: .
Liu P; China-Japan Friendship Institute of Clinical Medicine, Yinghuadong Road, Chaoyang District, Beijing, China. Electronic address: .
Wen P; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Xi'an, Shaanxi 710054, China. Electronic address: .
Zhang H; Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Yinghuadong Road, Chaoyang District, Beijing, China.
Guo W; Department of Joint Surgery, China-Japan Friendship Hospital, Yinghuadong Road, Chaoyang District, Beijing, China. Electronic address: .
Zhang Q; Department of Joint Surgery, China-Japan Friendship Hospital, Yinghuadong Road, Chaoyang District, Beijing, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 15; Vol. 766, pp. 145128. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*drug effects
Femur Head/*drug effects
Femur Head Necrosis/*drug therapy
Flavonoids/*pharmacology
MicroRNAs/*metabolism
Neovascularization, Pathologic/*drug therapy
Protective Agents/*pharmacology
Adipogenesis/drug effects ; Animals ; Cell Movement/drug effects ; Cell Survival/drug effects ; Endothelial Cells/metabolism ; Female ; Femur Head/metabolism ; Femur Head Necrosis/chemically induced ; Femur Head Necrosis/metabolism ; Glucocorticoids/metabolism ; Methylprednisolone/pharmacology ; Neovascularization, Pathologic/metabolism ; Osteocytes/drug effects ; Osteogenesis/drug effects ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Steroids/pharmacology ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
The Impact of Notch Signaling for Carcinogenesis and Progression of Nonmelanoma Skin Cancer: Lessons Learned from Cancer Stem Cells, Tumor Angiogenesis, and Beyond.
Autorzy :
Reichrath J; Department of Dermatology, Saarland University Medical Center, Homburg, Germany. .
Reichrath S; Department of Dermatology, Saarland University Medical Center, Homburg, Germany.; School of Health Professions, Saarland University Medical Center, Homburg, Germany.
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1287, pp. 123-154.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogenesis*
Neovascularization, Pathologic*
Signal Transduction*
Neoplastic Stem Cells/*pathology
Receptors, Notch/*metabolism
Skin Neoplasms/*metabolism
Skin Neoplasms/*pathology
Animals ; Carcinoma, Basal Cell/metabolism ; Carcinoma, Basal Cell/pathology ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Humans ; Skin Neoplasms/blood supply
Czasopismo naukowe
Tytuł :
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis.
Autorzy :
Tsukamoto K; Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. .
Shinzawa N; Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Yamada-oka, Suita, Osaka, 565-0871, Japan.; Department of Environmental Parasitology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Kawai A; Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Suzuki M; Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Kidoya H; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Yamada-oka, Suita, Osaka, 565-0871, Japan.
Takakura N; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Yamada-oka, Suita, Osaka, 565-0871, Japan.
Yamaguchi H; Division of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.; Department of Medical Technology, School of Nursing and Medical Care, Yokkaichi Nursing and Medical Care University, Yokkaichi, Mie, 512-8045, Japan.
Kameyama T; Division of Gene Expression Mechanism, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.; Department of Physiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Inagaki H; Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.; Genome and Transcriptome Analysis Center, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.
Kurahashi H; Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.; Genome and Transcriptome Analysis Center, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.
Horiguchi Y; Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Yamada-oka, Suita, Osaka, 565-0871, Japan.
Doi Y; Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. .; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15261, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 16; Vol. 11 (1), pp. 3571. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Bartonella/*pathogenicity
Neovascularization, Pathologic/*metabolism
Type V Secretion Systems/*metabolism
Vascular Endothelial Growth Factors/*metabolism
Virulence Factors/*metabolism
Animals ; Bartonella/classification ; Bartonella/genetics ; Cell Proliferation ; Gene Expression Profiling ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/microbiology ; Humans ; Mice ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/microbiology ; Protein Domains ; Type V Secretion Systems/chemistry ; Type V Secretion Systems/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Virulence Factors/chemistry ; Virulence Factors/genetics
Czasopismo naukowe
Tytuł :
Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs.
Autorzy :
Raimondi L; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
De Luca A; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Gallo A; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Costa V; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Russelli G; IRCCS ISMETT, Department of Research, Palermo, Italy.
Cuscino N; IRCCS ISMETT, Department of Research, Palermo, Italy.
Manno M; National Research Council of Italy, Institute of Byophysics, Palermo, Italy.
Raccosta S; National Research Council of Italy, Institute of Byophysics, Palermo, Italy.
Carina V; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Bellavia D; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Conigliaro A; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, Palermo, Italy.
Alessandro R; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, Palermo, Italy.
Fini M; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Preclinical and Surgical Studies, Bologna, Italy.
Conaldi PG; IRCCS ISMETT, Department of Research, Palermo, Italy.
Giavaresi G; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Preclinical and Surgical Studies, Bologna, Italy.
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Źródło :
Carcinogenesis [Carcinogenesis] 2020 Jul 10; Vol. 41 (5), pp. 666-677.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*genetics
Bone Neoplasms/*pathology
Endothelium, Vascular/*pathology
Exosomes/*pathology
MicroRNAs/*genetics
Neovascularization, Pathologic/*pathology
Osteosarcoma/*pathology
Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Endothelium, Vascular/metabolism ; Exosomes/genetics ; Exosomes/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Carotid intraplaque neovascularization predicts atherosclerotic renal artery stenosis in patients with carotid artery stenosis.
Autorzy :
Song Y; Department of Ultrasound, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China.
Dang Y; Department of Ultrasound, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China.
Cai H; Department of Vascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China.
Wang J; Department of Vascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China.
Liu B; Department of Ultrasound, Shaanxi Province People's Hospital, 256 West Youyi Road, Xi'an, Shaanxi, 710068, China.
Feng J; Department of Vascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China. Electronic address: .
Ruan L; Department of Ultrasound, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, China. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2020 Aug 28; Vol. 30 (9), pp. 1492-1499. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neovascularization, Pathologic*
Plaque, Atherosclerotic*
Ultrasonography*
Carotid Arteries/*diagnostic imaging
Carotid Stenosis/*diagnostic imaging
Renal Artery/*diagnostic imaging
Renal Artery Obstruction/*diagnostic imaging
Aged ; Biomarkers/blood ; Carotid Stenosis/blood ; Carotid Stenosis/epidemiology ; Carotid Stenosis/therapy ; China/epidemiology ; Contrast Media/administration & dosage ; Female ; Homocysteine/blood ; Humans ; Male ; Microbubbles ; Middle Aged ; Patient Admission ; Predictive Value of Tests ; Prevalence ; Renal Artery Obstruction/blood ; Renal Artery Obstruction/epidemiology ; Risk Assessment ; Risk Factors ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
[CCL2 promotes angiogenesis of primary rat cardiac microvascular endothelial cells].
Autorzy :
Lou Q; National and Local Joint Laboratory for Antibody Drug Development Techniques, Basic Medical School of Henan University, Kaifeng 475004, China. .
Liu YL; National and Local Joint Laboratory for Antibody Drug Development Techniques, Basic Medical School of Henan University, Kaifeng 475004, China.
Zhang SM; The Huaihe Clinical College of Henan University, Kaifeng 475000, China.
Li YY; National and Local Joint Laboratory for Antibody Drug Development Techniques, Basic Medical School of Henan University, Kaifeng 475004, China.
Huang XF; National and Local Joint Laboratory for Antibody Drug Development Techniques, Basic Medical School of Henan University, Kaifeng 475004, China.
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Źródło :
Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2020 Aug 25; Vol. 72 (4), pp. 441-448.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2*
Endothelial Cells*
Neovascularization, Pathologic*
Animals ; Endothelium, Vascular ; Heart ; Rats ; Signal Transduction
Czasopismo naukowe
Tytuł :
[Research progress of anti-angiogenic drugs in the treatment of small cell lung cancer].
Autorzy :
Wang J; Department of Pulmonary Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Li K; Department of Pulmonary Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
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Źródło :
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2020 Aug 23; Vol. 42 (8), pp. 624-628.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Antineoplastic Agents/*therapeutic use
Lung Neoplasms/*drug therapy
Neovascularization, Pathologic/*drug therapy
Small Cell Lung Carcinoma/*drug therapy
Angiogenesis Inhibitors/pharmacology ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Antineoplastic Agents/pharmacology ; Bevacizumab/pharmacology ; Bevacizumab/therapeutic use ; Humans ; Lung Neoplasms/pathology ; Neovascularization, Pathologic/pathology ; Precision Medicine ; Small Cell Lung Carcinoma/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Neovascularization in carotid atherosclerotic plaques can be effectively evaluated by superb microvascular imaging (SMI): Initial experience.
Autorzy :
Chen X; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.; Department of Medical Ultrasound, Maternal and Child Health Care Hospital of Tongzhou District, Beijing, China.
Wang H; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Jiang Y; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Li J; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Li N; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Kong J; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Zhang X; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Ye W; Department of Vascular Surgery, Peking Union Medical College Hospital, Beijing, China.
Zhao D; Department of Pathology, Peking Union Medical College Hospital, Beijing, China.
Cai S; Department of Medical Ultrasound, Peking Union Medical College Hospital, Beijing, China.
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Źródło :
Vascular medicine (London, England) [Vasc Med] 2020 Aug; Vol. 25 (4), pp. 328-333. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Neovascularization, Pathologic*
Plaque, Atherosclerotic*
Ultrasonography*
Carotid Arteries/*diagnostic imaging
Carotid Artery Diseases/*diagnostic imaging
Microvessels/*diagnostic imaging
Aged ; Blood Flow Velocity ; Carotid Arteries/pathology ; Carotid Arteries/physiopathology ; Carotid Arteries/surgery ; Carotid Artery Diseases/pathology ; Carotid Artery Diseases/physiopathology ; Carotid Artery Diseases/surgery ; Endarterectomy, Carotid ; Female ; Humans ; Image Interpretation, Computer-Assisted ; Male ; Microcirculation ; Microvessels/pathology ; Microvessels/physiopathology ; Middle Aged ; Predictive Value of Tests
Czasopismo naukowe
Tytuł :
Correlation of Cerebral White Matter Lesions with Carotid Intraplaque Neovascularization assessed by Contrast-enhanced Ultrasound.
Autorzy :
Wang Y; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China; First Clinical Medical School, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: .
Jiang C; Department of Public Health, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Huang H; Department of Ultrasound, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Liu N; Department of Ultrasound, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Wang Y; Department of Neurosurgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
Chen Z; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Liang S; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Wu M; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Jiang Y; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Wang X; GCP Center, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Zhou T; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China; First Clinical Medical School, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Chen H; Department of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Zhang L; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China; First Clinical Medical School, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. Electronic address: .
Li H; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China; First Clinical Medical School, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Aug; Vol. 29 (8), pp. 104928. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article
MeSH Terms :
Magnetic Resonance Imaging*
Neovascularization, Pathologic*
Plaque, Atherosclerotic*
Ultrasonography, Doppler, Color*
Carotid Artery Diseases/*diagnostic imaging
Contrast Media/*administration & dosage
Leukoencephalopathies/*diagnostic imaging
Phospholipids/*administration & dosage
Sulfur Hexafluoride/*administration & dosage
Aged ; Carotid Artery Diseases/complications ; Carotid Artery Diseases/pathology ; Female ; Humans ; Leukoencephalopathies/complications ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Assessment ; Risk Factors
Czasopismo naukowe

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