Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Nerve Tissue Proteins"" wg kryterium: Temat


Tytuł :
Knockdown of the prognostic cancer stem cell marker Musashi-1 decreases radio-resistance while enhancing apoptosis in hormone receptor-positive breast cancer cells via p21 .
Autorzy :
Troschel FM; Department of Radiation Oncology, University Hospital Münster, 48149, Münster, Germany. .
Palenta H; Department of Gynecology and Obstetrics, University Hospital Münster, 48149, Münster, Germany.
Borrmann K; Department of Radiation Oncology, University Hospital Münster, 48149, Münster, Germany.
Heshe K; Department of Radiation Oncology, University Hospital Münster, 48149, Münster, Germany.
Hua SH; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117594, Singapore.
Yip GW; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117594, Singapore.
Kiesel L; Department of Gynecology and Obstetrics, University Hospital Münster, 48149, Münster, Germany.
Eich HT; Department of Radiation Oncology, University Hospital Münster, 48149, Münster, Germany.
Götte M; Department of Gynecology and Obstetrics, University Hospital Münster, 48149, Münster, Germany.
Greve B; Department of Radiation Oncology, University Hospital Münster, 48149, Münster, Germany.
Pokaż więcej
Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Nov; Vol. 147 (11), pp. 3299-3312. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*metabolism
Breast Neoplasms/*radiotherapy
Cyclin-Dependent Kinase Inhibitor p21/*metabolism
Neoplastic Stem Cells/*metabolism
Neoplastic Stem Cells/*radiation effects
Nerve Tissue Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Aged ; Apoptosis/physiology ; Breast Neoplasms/pathology ; Cell Proliferation/physiology ; Cyclin-Dependent Kinase Inhibitor p21/biosynthesis ; Down-Regulation ; Female ; Gene Knockdown Techniques ; Humans ; MCF-7 Cells ; Neoplastic Stem Cells/pathology ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Prognosis ; RNA-Binding Proteins/biosynthesis ; RNA-Binding Proteins/genetics ; Radiation Tolerance
Czasopismo naukowe
Tytuł :
Piezo1-Pannexin1 complex couples force detection to ATP secretion in cholangiocytes.
Autorzy :
Desplat A; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Penalba V; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Gros E; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Parpaite T; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Coste B; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Delmas P; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Dec 06; Vol. 153 (12). Date of Electronic Publication: 2021 Oct 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Triphosphate*
Connexins*/genetics
Epithelial Cells*/metabolism
Ion Channels*/genetics
Ion Channels*/metabolism
Nerve Tissue Proteins*/genetics
Animals ; Calcium/metabolism ; Cell Membrane/metabolism ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł :
Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis.
Autorzy :
Xie L; Department of Gastroenterology, The People's Hospital of China Three Gorges University and The First People's Hospital of Yichang, Yichang, Hubei Province, China.
Pan Z; Department of Gastroenterology, The People's Hospital of China Three Gorges University and The First People's Hospital of Yichang, Yichang, Hubei Province, China.
Pokaż więcej
Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 886-897.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/pathology
Homeodomain Proteins/*genetics
MicroRNAs/*genetics
Nerve Tissue Proteins/*genetics
RNA, Circular/*genetics
Cell Line, Tumor ; Female ; Homeodomain Proteins/metabolism ; Humans ; Male ; MicroRNAs/metabolism ; Middle Aged ; Nerve Tissue Proteins/metabolism ; RNA, Circular/metabolism
Czasopismo naukowe
Tytuł :
Neuronal pentraxin II (NPTX2) hypermethylation promotes cell proliferation but inhibits cell cycle arrest and apoptosis in gastric cancer cells by suppressing the p53 signaling pathway.
Autorzy :
Xu G; Department of Gastroenterology, First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province, China.
Fan L; Department of Gastrointestinal Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province, China.
Zhao S; Department of Gastrointestinal Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province, China.
OuYang C; Department of Gastroenterology, First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province, China.
Pokaż więcej
Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 1311-1323.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*genetics
C-Reactive Protein/*metabolism
Cell Cycle Checkpoints/*genetics
DNA Methylation/*genetics
Nerve Tissue Proteins/*metabolism
Stomach Neoplasms/*genetics
Stomach Neoplasms/*pathology
Tumor Suppressor Protein p53/*metabolism
C-Reactive Protein/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Models, Biological ; Nerve Tissue Proteins/genetics ; Promoter Regions, Genetic/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Design and synthesis of the first indole-based blockers of Panx-1 channel.
Autorzy :
Crocetti L; Neurofarba, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy. Electronic address: .
Guerrini G; Neurofarba, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy. Electronic address: .
Puglioli S; Neurofarba, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy. Electronic address: .
Giovannoni MP; Neurofarba, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy. Electronic address: .
Di Cesare Mannelli L; Neurofarba, Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy. Electronic address: .
Lucarini E; Neurofarba, Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy. Electronic address: .
Ghelardini C; Neurofarba, Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy. Electronic address: .
Wang J; Department of Physiology and Biophysics, University of Miami School of Medicine, 1600 N.W. 10th Avenue Miami, Florida, 33136, USA. Electronic address: .
Dahl G; Department of Physiology and Biophysics, University of Miami School of Medicine, 1600 N.W. 10th Avenue Miami, Florida, 33136, USA. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Nov 05; Vol. 223, pp. 113650. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Indoles/*chemistry
Nerve Tissue Proteins/*metabolism
Animals ; Binding Sites ; Connexins/antagonists & inhibitors ; Connexins/metabolism ; Disease Models, Animal ; Humans ; Indoles/pharmacology ; Indoles/therapeutic use ; Male ; Membrane Potentials/drug effects ; Mice ; Molecular Docking Simulation ; Nerve Tissue Proteins/antagonists & inhibitors ; Neuralgia/chemically induced ; Neuralgia/drug therapy ; Neuralgia/pathology ; Oocytes/drug effects ; Oocytes/physiology ; Oxaliplatin/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Conformational exchange of fatty acid binding protein induced by protein-nanodisc interactions.
Autorzy :
Lu Y; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
Yang D; Department of Biological Sciences, National University of Singapore, Singapore, Singapore. Electronic address: .
Pokaż więcej
Źródło :
Biophysical journal [Biophys J] 2021 Nov 02; Vol. 120 (21), pp. 4672-4681. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fatty Acid-Binding Proteins*
Nerve Tissue Proteins*
Fatty Acid-Binding Protein 7 ; Fatty Acids ; Humans ; Neoplasm Proteins
Czasopismo naukowe
Tytuł :
Genetically identified amygdala-striatal circuits for valence-specific behaviors.
Autorzy :
Zhang X; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. .
Guan W; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Yang T; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Furlan A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Xiao X; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Yu K; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
An X; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Department of Neurobiology, Duke University School of Medicine, Durham, NC, USA.
Galbavy W; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Program in Neuroscience, Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, USA.
Ramakrishnan C; Howard Hughes Medical Institute (HHMI), Stanford University, Stanford, CA, USA.; Department of Bioengineering and Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Deisseroth K; Howard Hughes Medical Institute (HHMI), Stanford University, Stanford, CA, USA.; Department of Bioengineering and Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Ritola K; Howard Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.
Hantman A; Howard Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.
He M; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Josh Huang Z; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Department of Neurobiology, Duke University School of Medicine, Durham, NC, USA.
Li B; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. .
Pokaż więcej
Źródło :
Nature neuroscience [Nat Neurosci] 2021 Nov; Vol. 24 (11), pp. 1586-1600. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amygdala/*metabolism
Attention/*physiology
Avoidance Learning/*physiology
Corpus Striatum/*metabolism
DNA-Binding Proteins/*genetics
Nerve Net/*metabolism
Nerve Tissue Proteins/*genetics
Animals ; DNA-Binding Proteins/biosynthesis ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Motivation/physiology ; Nerve Tissue Proteins/biosynthesis
Czasopismo naukowe
Tytuł :
The exploration of neuroendocrine regulation of crustacean hyperglycemic hormone (CHH) on innate immunity of Litopenaeus vannamei under ammonia-N stress.
Autorzy :
Zhang X; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Pan L; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China. Electronic address: .
Tong R; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Li Y; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Si L; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Chen Y; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Li D; The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.
Pokaż więcej
Źródło :
Molecular immunology [Mol Immunol] 2021 Nov; Vol. 139, pp. 50-64. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthropod Proteins/*immunology
Immunity, Innate/*immunology
Invertebrate Hormones/*immunology
Nerve Tissue Proteins/*immunology
Penaeidae/*immunology
Stress, Physiological/*immunology
Ammonia/toxicity ; Animals ; Arthropod Proteins/metabolism ; Environment ; Invertebrate Hormones/metabolism ; Nerve Tissue Proteins/metabolism ; Penaeidae/metabolism ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
LncRNA BASP1-AS1 interacts with YBX1 to regulate Notch transcription and drives the malignancy of melanoma.
Autorzy :
Li Y; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.
Gao Y; Department of Dermatology, The First Afflicated Hospital of Sun Yat-sen University, Guangzhou, China.
Niu X; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.
Tang M; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.
Li J; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.
Song B; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.; School of Dentistry, Cardiff University, Cardiff, UK.
Guan X; Department of Dermatology, The First Hospital of China Medical University and National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, China.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Nov; Vol. 112 (11), pp. 4526-4542. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Melanoma/*metabolism
Membrane Proteins/*metabolism
Nerve Tissue Proteins/*metabolism
RNA, Long Noncoding/*metabolism
Receptor, Notch3/*metabolism
Repressor Proteins/*metabolism
Skin Neoplasms/*metabolism
Y-Box-Binding Protein 1/*metabolism
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; GTPase-Activating Proteins/metabolism ; Gene Silencing ; Humans ; Male ; Melanoma/mortality ; Melanoma/pathology ; Membrane Proteins/genetics ; Mice ; Mice, Inbred BALB C ; Murine pneumonia virus ; Neoplasm Invasiveness ; Neoplasm Proteins/metabolism ; Neoplasm Transplantation ; Neoplastic Stem Cells ; Nerve Tissue Proteins/genetics ; Prognosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Random Allocation ; Repressor Proteins/genetics ; Skin Neoplasms/mortality ; Skin Neoplasms/pathology ; Transcription, Genetic ; Up-Regulation
SCR Disease Name :
Melanoma, Cutaneous Malignant
Czasopismo naukowe
Tytuł :
BEX2 is required for maintaining dormant cancer stem cell in hepatocellular carcinoma.
Autorzy :
Fukushi D; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori, Japan.; Division of Cancer Stem Cell, Tohoku University Graduate School of Medicine, Sendai, Japan.; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Shibuya-Takahashi R; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori, Japan.
Mochizuki M; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori, Japan.
Fujimori H; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori, Japan.
Kogure T; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Sugai T; Department of Gastroenterology, Miyagi Cancer Center, Natori, Japan.
Iwai W; Department of Gastroenterology, Miyagi Cancer Center, Natori, Japan.
Wakui Y; Department of Gastroenterology, Miyagi Cancer Center, Natori, Japan.
Abue M; Department of Gastroenterology, Miyagi Cancer Center, Natori, Japan.
Murakami K; Division of Pathology, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Nakamura Y; Division of Pathology, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Yasuda J; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, Natori, Japan.
Yamaguchi K; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, Natori, Japan.
Sugamura K; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, Natori, Japan.
Shibata C; Gastroenterologic and Hepato-Biliary-Pancreatic Surgery, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Katayose Y; Gastroenterologic and Hepato-Biliary-Pancreatic Surgery, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Satoh K; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.
Tamai K; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori, Japan.; Division of Cancer Stem Cell, Tohoku University Graduate School of Medicine, Sendai, Japan.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Nov; Vol. 112 (11), pp. 4580-4592. Date of Electronic Publication: 2021 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*metabolism
Liver Neoplasms/*metabolism
Neoplastic Stem Cells/*metabolism
Nerve Tissue Proteins/*metabolism
Aged ; Aldehyde Dehydrogenase/metabolism ; Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cholangiocarcinoma/metabolism ; Cisplatin/pharmacology ; Female ; Gene Silencing ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Male ; Mice ; Nerve Tissue Proteins/genetics ; Organoids ; Prognosis ; Spheroids, Cellular
Czasopismo naukowe
Tytuł :
Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor.
Autorzy :
Brahimi F; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Galan A; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Siegel S; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Szobota S; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Sarunic MV; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Foster AC; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Saragovi HU; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.) .
Pokaż więcej
Źródło :
Molecular pharmacology [Mol Pharmacol] 2021 Nov; Vol. 100 (5), pp. 491-501. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Nerve Growth Factors/*metabolism
Nerve Tissue Proteins/*metabolism
Neuroprotection/*physiology
Protein Engineering/*methods
Receptor, trkA/*metabolism
Receptors, Growth Factor/*metabolism
Animals ; Axotomy/adverse effects ; Diabetic Neuropathies/drug therapy ; Diabetic Neuropathies/genetics ; Diabetic Neuropathies/metabolism ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Nerve Growth Factors/administration & dosage ; Nerve Growth Factors/genetics ; Nerve Tissue Proteins/genetics ; Neuroprotection/drug effects ; Optic Nerve/drug effects ; Optic Nerve/metabolism ; Receptor, trkA/genetics ; Receptors, Growth Factor/genetics
Czasopismo naukowe
Tytuł :
Slo2/K Na Channels in Drosophila Protect against Spontaneous and Induced Seizure-like Behavior Associated with an Increased Persistent Na Current.
Autorzy :
Byers N; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523.
Hahm ET; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523.
Tsunoda S; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 .
Pokaż więcej
Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Oct 27; Vol. 41 (43), pp. 9047-9063. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Nerve Tissue Proteins/*biosynthesis
Potassium Channels, Sodium-Activated/*biosynthesis
Seizures/*metabolism
Seizures/*prevention & control
Animals ; Animals, Genetically Modified ; Drosophila ; Female ; Male ; Nerve Tissue Proteins/genetics ; Potassium Channels, Sodium-Activated/genetics ; Seizures/genetics
Czasopismo naukowe
Tytuł :
PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.
Autorzy :
Chen YJ; Department of Cell & Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, BSRB 3043, Ann Arbor, MI, 48109, USA.
Knupp J; Department of Cell & Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, BSRB 3043, Ann Arbor, MI, 48109, USA.; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI, USA.
Arunagiri A; Division of Metabolism Endocrinology & Diabetes, University of Michigan Medical School, Ann Arbor, MI, USA.
Haataja L; Division of Metabolism Endocrinology & Diabetes, University of Michigan Medical School, Ann Arbor, MI, USA.
Arvan P; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI, USA. .; Division of Metabolism Endocrinology & Diabetes, University of Michigan Medical School, Ann Arbor, MI, USA. .
Tsai B; Department of Cell & Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, BSRB 3043, Ann Arbor, MI, 48109, USA. .; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Oct 13; Vol. 12 (1), pp. 5991. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Carrier Proteins/*genetics
Endoplasmic Reticulum/*metabolism
Insulin-Secreting Cells/*metabolism
Membrane Proteins/*genetics
Nerve Tissue Proteins/*genetics
Proinsulin/*genetics
Receptors, Progesterone/*genetics
Animals ; Autophagy/genetics ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Endoplasmic Reticulum/genetics ; Gene Expression ; HEK293 Cells ; Humans ; Insulin-Secreting Cells/cytology ; Islets of Langerhans/cytology ; Islets of Langerhans/metabolism ; Lysosomes/metabolism ; Membrane Proteins/metabolism ; Mice ; Mutation ; Nerve Tissue Proteins/metabolism ; Primary Cell Culture ; Proinsulin/metabolism ; Protein Binding ; Protein Domains ; Protein Folding ; Proteolysis ; Rats ; Receptors, Progesterone/metabolism
Czasopismo naukowe
Tytuł :
The porcine cerebellin gene family.
Autorzy :
Larsen K; Department of Molecular Biology and Genetics, Aarhus University, C.F. Møllers Allé 3, DK-8000 Aarhus C, Denmark. Electronic address: .
Pokaż więcej
Źródło :
Gene [Gene] 2021 Oct 05; Vol. 799, pp. 145852. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Brain/*embryology
Nerve Tissue Proteins/*genetics
Animals ; Brain/physiology ; Cloning, Molecular ; Female ; Glycosylation ; Multigene Family ; Nerve Tissue Proteins/metabolism ; Open Reading Frames ; Protein Precursors/genetics ; Swine
Czasopismo naukowe
Tytuł :
Overexpression of the Gene Encoding Neurosecretory Protein GL Precursor Prevents Excessive Fat Accumulation in the Adipose Tissue of Mice Fed a Long-Term High-Fat Diet.
Autorzy :
Fukumura K; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Narimatsu Y; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Moriwaki S; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Iwakoshi-Ukena E; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Furumitsu M; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Ukena K; Laboratory of Neurometabolism, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521, Japan.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Oct 03; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue/*metabolism
Nerve Tissue Proteins/*physiology
Adipose Tissue, White/metabolism ; Animals ; Biomarkers/blood ; Body Weight ; Diet, High-Fat ; Energy Metabolism/genetics ; Feeding Behavior ; Glucose Tolerance Test ; Insulin/blood ; Lipid Metabolism/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Nerve Tissue Proteins/genetics ; Obesity/blood ; Obesity/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Truncating variants in the SHANK1 gene are associated with a spectrum of neurodevelopmental disorders.
Autorzy :
May HJ; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA. .
Jeong J; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Revah-Politi A; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Cohen JS; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chassevent A; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.
Baptista J; Exeter Genomics Laboratory, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; Institute of Biomedical & Clinical Science, University of Exeter Medical School, Exeter, UK.
Baugh EH; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Bier L; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Bottani A; Division of Genetic Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Carminho A Rodrigues MT; Division of Genetic Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Conlon C; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.
Fluss J; Pediatric Neurology Unit, Pediatrics Subspecialties Service, Geneva Children's Hospital, Geneva, Switzerland.
Guipponi M; Division of Genetic Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Kim CA; Genetics Unit, Instituto da Crianca, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.
Matsumoto N; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Person R; Clinical Genomics Program, GeneDx, Gaithersburg, MD, USA.
Primiano M; Division of Clinical Genetics, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Rankin J; Department of Clinical Genetics, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
Shinawi M; Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Smith-Hicks C; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Telegrafi A; Clinical Genomics Program, GeneDx, Gaithersburg, MD, USA.
Toy S; Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Uchiyama Y; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.; Department of Rare Disease Genomics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Aggarwal V; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Roche KW; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Anyane-Yeboa K; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA. .; Division of Clinical Genetics, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA. .
Pokaż więcej
Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Oct; Vol. 23 (10), pp. 1912-1921. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Nerve Tissue Proteins*/genetics
Neurodevelopmental Disorders*/genetics
HEK293 Cells ; Humans ; Neurons ; Phenotype ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Arc/Arg3.1 function in long-term synaptic plasticity: Emerging mechanisms and unresolved issues.
Autorzy :
Zhang H; Department of Biomedicine, University of Bergen, Bergen, Norway.
Bramham CR; Department of Biomedicine, University of Bergen, Bergen, Norway.
Pokaż więcej
Źródło :
The European journal of neuroscience [Eur J Neurosci] 2021 Oct; Vol. 54 (8), pp. 6696-6712. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cytoskeletal Proteins*
Nerve Tissue Proteins*
Long-Term Potentiation ; Neuronal Plasticity ; Synapses
Czasopismo naukowe
Tytuł :
Deep transcriptomic profiling of Dahl salt-sensitive rat kidneys with mutant form of Resp18.
Autorzy :
Ashraf UM; Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA.
Mell B; Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA.
Jose PA; Department of Medicine, Division of Kidney Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20052, USA; Department of Pharmacology and Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20052, USA.
Kumarasamy S; Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA; Department of Biomedical Sciences, Ohio University, Athens, OH, 45701, USA; Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA. Electronic address: .
Pokaż więcej
Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Oct 01; Vol. 572, pp. 35-40. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney/*metabolism
Nerve Tissue Proteins/*genetics
Animals ; Gene Expression Profiling ; Male ; Mutation ; Nerve Tissue Proteins/metabolism ; Rats ; Rats, Inbred Dahl
Czasopismo naukowe
Tytuł :
Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress.
Autorzy :
Ito N; Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan. Electronic address: .
Sasaki K; Alliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki 305-8572, Japan; Open Innovation Laboratory for Food and Medicinal Resource Engineering, National Institute of Advanced Industrial Science and Technology (AIST) and University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki 305-8572, Japan.
Hirose E; Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan.
Nagai T; Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan; Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan; Laboratory of Biochemical Pharmacology for Phytomedicines, Ōmura Satoshi Memorial Institute, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan.
Isoda H; Alliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki 305-8572, Japan; Open Innovation Laboratory for Food and Medicinal Resource Engineering, National Institute of Advanced Industrial Science and Technology (AIST) and University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki 305-8572, Japan; Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki 305-8572, Japan.
Odaguchi H; Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan.
Pokaż więcej
Źródło :
Gene [Gene] 2022 Jan 05; Vol. 806, pp. 145920. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Social Defeat*
Antidepressive Agents/*pharmacology
Depression/*prevention & control
Drugs, Chinese Herbal/*pharmacology
Nerve Tissue Proteins/*genetics
Stress, Psychological/*drug therapy
Administration, Oral ; Animals ; Depression/genetics ; Depression/physiopathology ; Depression/psychology ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Ontology ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Japan ; Male ; Medicine, Kampo/methods ; Mice ; Mice, Inbred BALB C ; Milnacipran/pharmacology ; Molecular Sequence Annotation ; Nerve Tissue Proteins/classification ; Nerve Tissue Proteins/metabolism ; Oligonucleotide Array Sequence Analysis ; Recurrence ; Stress, Psychological/genetics ; Stress, Psychological/physiopathology
Czasopismo naukowe
Tytuł :
TRAPPC4 regulates the intracellular trafficking of PD-L1 and antitumor immunity.
Autorzy :
Ren Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Qian Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ai L; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xie Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Gao Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhuang Z; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen J; Division of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen YX; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Fang JY; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Sep 13; Vol. 12 (1), pp. 5405. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B7-H1 Antigen/*immunology
Colorectal Neoplasms/*immunology
Gene Expression Regulation, Neoplastic/*immunology
Nerve Tissue Proteins/*immunology
Vesicular Transport Proteins/*immunology
Animals ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Cell Line, Tumor ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Cytotoxicity, Immunologic/genetics ; Cytotoxicity, Immunologic/immunology ; Endosomes/immunology ; Endosomes/metabolism ; HCT116 Cells ; Humans ; Intracellular Space/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/immunology ; Programmed Cell Death 1 Receptor/metabolism ; Protein Binding ; Protein Transport ; RNA Interference ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies