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Wyszukujesz frazę ""Netrin-1"" wg kryterium: Temat


Tytuł :
Inhibition of vascular adventitial remodeling by netrin-1 in diabetic rats.
Autorzy :
Wang HF; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Yu QQ; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Zheng RF; Xinjiang Key Laboratory of Uighur Medicines, Xinjiang Institute of Materia Medica, Urumqi, Xinjiang, China.
Xu M; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
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Źródło :
The Journal of endocrinology [J Endocrinol] 2020 Mar; Vol. 244 (3), pp. 445-458.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adventitia/*physiopathology
Diabetes Mellitus, Type 2/*metabolism
Netrin-1/*metabolism
Adventitia/metabolism ; Animals ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/physiopathology ; Fibroblasts/metabolism ; Humans ; Male ; NADPH Oxidase 4/genetics ; NADPH Oxidase 4/metabolism ; Netrin-1/genetics ; Neurons/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling.
Autorzy :
Huyghe A; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Furlan G; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Ozmadenci D; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Galonska C; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Charlton J; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Gaume X; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Combémorel N; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Riemenschneider C; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Allègre N; GReD, Université Clermont Auvergne, CNRS, INSERM, BP38, Clermont-Ferrand, France.
Zhang J; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
Wajda P; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Rama N; Apoptosis, Cancer and Development Laboratory, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Vieugué P; Apoptosis, Cancer and Development Laboratory, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.
Durand I; Cytometry Facility, Université de Lyon, Université Claude Bernard Lyon 1, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, INSERM 1052, CNRS 5286, Lyon, France.
Brevet M; Research Pathology platform, Department of translational research and innovation, Centre Léon Bérard, Lyon, France.
Gadot N; Research Pathology platform, Department of translational research and innovation, Centre Léon Bérard, Lyon, France.
Imhof T; Institute for Dental Research and Oral Musculoskeletal Research, Center for Biochemistry, University of Cologne, Cologne, Germany.
Merrill BJ; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
Koch M; Institute for Dental Research and Oral Musculoskeletal Research, Center for Biochemistry, University of Cologne, Cologne, Germany.
Mehlen P; Apoptosis, Cancer and Development Laboratory, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France.; Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France.
Chazaud C; GReD, Université Clermont Auvergne, CNRS, INSERM, BP38, Clermont-Ferrand, France.
Meissner A; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Lavial F; Cellular Reprogramming and Oncogenesis Laboratory, Equipe labellisée la Ligue contre le cancer, Labex DEVweCAN, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de recherche en cancérologie de Lyon, Lyon, France. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2020 Apr; Vol. 22 (4), pp. 389-400. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Nerve Tissue Proteins/*genetics
Netrin Receptors/*genetics
Netrin-1/*genetics
Receptors, Cell Surface/*genetics
Wnt Signaling Pathway/*genetics
Animals ; Cell Line ; Embryo, Mammalian ; Extracellular Signal-Regulated MAP Kinases/genetics ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Focal Adhesion Kinase 1/genetics ; Focal Adhesion Kinase 1/metabolism ; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors ; Glycogen Synthase Kinase 3 beta/genetics ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Leukemia Inhibitory Factor/genetics ; Leukemia Inhibitory Factor/metabolism ; MAP Kinase Kinase 1/antagonists & inhibitors ; MAP Kinase Kinase 1/genetics ; MAP Kinase Kinase 1/metabolism ; MAP Kinase Kinase 2/antagonists & inhibitors ; MAP Kinase Kinase 2/genetics ; MAP Kinase Kinase 2/metabolism ; Male ; Mice ; Mice, Knockout ; Mice, SCID ; Mouse Embryonic Stem Cells/cytology ; Mouse Embryonic Stem Cells/metabolism ; Nerve Tissue Proteins/metabolism ; Netrin Receptors/metabolism ; Netrin-1/metabolism ; Pluripotent Stem Cells/cytology ; Pluripotent Stem Cells/metabolism ; Protein Phosphatase 2/genetics ; Protein Phosphatase 2/metabolism ; Receptors, Cell Surface/metabolism ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Netrin-1 and Its Receptor DCC Are Causally Implicated in Melanoma Progression.
Autorzy :
Boussouar A; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.
Tortereau A; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.; Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France.
Manceau A; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.
Paradisi A; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.
Gadot N; Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France.
Vial J; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.
Neves D; Netris Pharma, Lyon, France.
Larue L; Institut Curie, PSL Research University, INSERM U1021, Normal and Pathological Development of Melanocytes, Orsay, France.; Univ Paris-Sud, Univ Paris-Saclay, CNRS UMR3347, Orsay, France.; Equipe Labellisée Ligue Contre le Cancer, Orsay, France.
Battistella M; Université Paris Diderot, Inserm, UMR_S1165, Paris, France, Laboratoire de pathologie, Hôpital Saint Louis, APHP, Paris, France.
Leboeuf C; Université Paris Diderot, Inserm, UMR_S1165, Paris, France, Laboratoire de pathologie, Hôpital Saint Louis, APHP, Paris, France.
Lebbé C; Service de dermatologie, Hôpital Saint Louis, APHP, Paris, France.
Janin A; Université Paris Diderot, Inserm, UMR_S1165, Paris, France, Laboratoire de pathologie, Hôpital Saint Louis, APHP, Paris, France.
Mehlen P; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France. .; Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France.
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Źródło :
Cancer research [Cancer Res] 2020 Feb 15; Vol. 80 (4), pp. 747-756. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
DCC Receptor/*metabolism
Melanoma/*pathology
Netrin-1/*metabolism
Skin Neoplasms/*pathology
Tumor Suppressor Proteins/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; DCC Receptor/genetics ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Melanoma/genetics ; Melanoma/therapy ; Mice ; Mice, Transgenic ; Netrin-1/antagonists & inhibitors ; Proto-Oncogene Proteins B-raf/genetics ; Skin/pathology ; Skin Neoplasms/genetics ; Skin Neoplasms/therapy ; Tumor Suppressor Proteins/genetics ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.
Autorzy :
Boyer NP; Neurobiology Curriculum, University of North Carolina, Chapel Hill, Chapel Hill, NC.
McCormick LE; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, Chapel Hill, NC.
Menon S; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, Chapel Hill, NC.
Urbina FL; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, Chapel Hill, NC.
Gupton SL; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, Chapel Hill, NC.; Neuroscience Center, University of North Carolina, Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, NC.
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Źródło :
The Journal of cell biology [J Cell Biol] 2020 Jan 06; Vol. 219 (1).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Axon Guidance/*physiology
Cell Adhesion Molecules/*metabolism
Cytoskeletal Proteins/*physiology
Microfilament Proteins/*metabolism
Nerve Tissue Proteins/*physiology
Netrin-1/*metabolism
Phosphoproteins/*metabolism
Pseudopodia/*physiology
Tripartite Motif Proteins/*physiology
Ubiquitin/*metabolism
Ubiquitin-Protein Ligases/*physiology
Animals ; Cell Adhesion Molecules/genetics ; Female ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microfilament Proteins/genetics ; Netrin-1/genetics ; Neurons/cytology ; Neurons/metabolism ; Phosphoproteins/genetics ; Ubiquitination
Czasopismo naukowe
Tytuł :
Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice.
Autorzy :
Ni S; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, 410008, P. R. China.
Ling Z; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Department of Spinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 51008, P. R. China.
Wang X; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Cao Y; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, 410008, P. R. China.
Wu T; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, 410008, P. R. China.
Deng R; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Crane JL; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Skolasky R; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Demehri S; Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Zhen G; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Jain A; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Wu P; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Pan D; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Hu B; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Lyu X; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Li Y; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Chen H; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Qi H; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Guan Y; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Dong X; Department of Neuroscience, Neurosurgery, and Dermatology, Center of Sensory Biology, The Johns Hopkins University School of Medicine, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA.
Wan M; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Zou X; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Department of Spinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 51008, P. R. China.
Lu H; Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, 410008, P. R. China.
Hu J; Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, 410008, P. R. China. .
Cao X; Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. .
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Źródło :
Nature communications [Nat Commun] 2019 Dec 10; Vol. 10 (1), pp. 5643. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypersensitivity/*pathology
Motor Endplate/*pathology
Netrin-1/*metabolism
Osteoclasts/*metabolism
Sensory Receptor Cells/*metabolism
Spine/*pathology
Aging/pathology ; Animals ; Behavior, Animal ; Dinoprostone ; Disease Models, Animal ; Humans ; Hyperalgesia/pathology ; Lumbar Vertebrae/pathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Netrin-1/deficiency ; Pain/pathology ; Porosity ; Signal Transduction
Czasopismo naukowe
Tytuł :
Decreased Serum Netrin-1 as a Predictor for Post-Stroke Depression in Chinese Patients with Acute Ischemic Stroke.
Autorzy :
Chen Z; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Cao T; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Zhong X; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Wu Y; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Fu W; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Fan C; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Jiang Y; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Zhu Y; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Peng J; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Li P; Department of Neurology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China.
Tan J; Department of Endocrinology, Mianzhu People's Hospital, Mianzhu 618200, Sichuan, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105149. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Depression/*blood
Netrin-1/*blood
Stroke/*blood
Aged ; Biomarkers/blood ; China ; Depression/diagnosis ; Depression/etiology ; Down-Regulation ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Factors ; Stroke/complications ; Stroke/diagnosis ; Time Factors
Czasopismo naukowe
Tytuł :
The role of netrin-1 in the mouse cornea during Aspergillus fumigatus infection.
Autorzy :
Zhou Y; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lin J; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Peng X; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Li C; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang J; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wang Q; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhu G; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
You J; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhao G; Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2019 Jun; Vol. 71, pp. 372-381. Date of Electronic Publication: 2019 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Aspergillosis/*metabolism
Aspergillus fumigatus/*physiology
Epithelium, Corneal/*metabolism
Netrin-1/*metabolism
Receptor, Adenosine A2B/*metabolism
Adenosine A2 Receptor Antagonists/administration & dosage ; Animals ; Cell Movement ; Cell Proliferation ; Cytokines/genetics ; Cytokines/metabolism ; Epithelium, Corneal/pathology ; Female ; Humans ; Inflammation Mediators/metabolism ; Mice ; Mice, Inbred C57BL ; Netrin-1/administration & dosage ; Netrin-1/genetics ; RAW 264.7 Cells ; Recombinant Proteins/administration & dosage ; Xanthines/administration & dosage
Czasopismo naukowe
Tytuł :
Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling.
Autorzy :
Shao Q; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Yang T; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Huang H; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Majumder T; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Khot BA; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Khouzani MM; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Alarmanazi F; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Gore YK; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
Liu G; Department of Biological Sciences, University of Toledo, Toledo, OH, United States of America.
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Źródło :
PloS one [PLoS One] 2019 Jun 21; Vol. 14 (6), pp. e0218811. Date of Electronic Publication: 2019 Jun 21 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Axon Guidance/*genetics
Nervous System Diseases/*genetics
Netrin-1/*physiology
Tubulin/*genetics
Animals ; Axons/physiology ; Cell Movement/genetics ; Cells, Cultured ; Chick Embryo ; Female ; HEK293 Cells ; HeLa Cells ; Humans ; Male ; Mice ; Mutation, Missense ; Netrin Receptors/genetics ; Netrin Receptors/metabolism ; Netrin-1/genetics ; Netrin-1/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.
Autorzy :
Brignani S; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Raj DDA; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Schmidt ERE; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Düdükcü Ö; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Adolfs Y; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
De Ruiter AA; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Rybiczka-Tesulov M; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Verhagen MG; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
van der Meer C; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Broekhoven MH; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Moreno-Bravo JA; Institut de la Vision, Sorbonne Université, INSERM, CNRS, 17 Rue Moreau, 75012 Paris, France.
Grossouw LM; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Dumontier E; Montreal Neurological Institute, 3801 University, Montréal, QC H3A 2B4, Canada.
Cloutier JF; Montreal Neurological Institute, 3801 University, Montréal, QC H3A 2B4, Canada.
Chédotal A; Institut de la Vision, Sorbonne Université, INSERM, CNRS, 17 Rue Moreau, 75012 Paris, France.
Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Aug 19; Vol. 107 (4), pp. 684-702.e9. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement/*physiology
Dopaminergic Neurons/*metabolism
GABAergic Neurons/*metabolism
Netrin-1/*metabolism
Prosencephalon/*metabolism
Substantia Nigra/*metabolism
Animals ; Axons/metabolism ; Dopaminergic Neurons/cytology ; GABAergic Neurons/cytology ; Mice ; Mice, Transgenic ; Substantia Nigra/cytology
Czasopismo naukowe
Tytuł :
Solution Structure of C. elegans UNC-6: A Nematode Paralogue of the Axon Guidance Protein Netrin-1.
Autorzy :
Krahn N; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
Meier M; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada.
Reuten R; Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Koch M; Institute for Dental Research and Oral Musculoskeletal Biology, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Stetefeld J; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada; Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: .
Patel TR; Alberta RNA Research and Training Institute, Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; DiscoveryLab and Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2019 Jun 04; Vol. 116 (11), pp. 2121-2130. Date of Electronic Publication: 2019 May 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axon Guidance*
Sequence Homology, Amino Acid*
Caenorhabditis elegans Proteins/*chemistry
Netrin-1/*chemistry
Netrins/*chemistry
Amino Acid Sequence ; Caenorhabditis elegans Proteins/metabolism ; Evolution, Molecular ; Netrin-1/metabolism ; Netrins/metabolism ; Osmolar Concentration ; Protein Domains ; Solutions
Czasopismo naukowe
Tytuł :
Exogenous Netrin-1 Inhibits Autophagy of Ischemic Brain Tissues and Hypoxic Neurons via PI3K/mTOR Pathway in Ischemic Stroke.
Autorzy :
Tang T; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China; School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China.
Gao D; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China; School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China.
Yang X; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China.
Hua X; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China.
Li S; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China. Electronic address: .
Sun H; Department of Neurosurgery, Affiliated Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, PR China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2019 May; Vol. 28 (5), pp. 1338-1345. Date of Electronic Publication: 2019 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy/*drug effects
Brain/*drug effects
Infarction, Middle Cerebral Artery/*drug therapy
Netrin-1/*administration & dosage
Neurons/*drug effects
Neuroprotective Agents/*administration & dosage
Phosphatidylinositol 3-Kinase/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Animals ; Brain/enzymology ; Brain/pathology ; Cell Hypoxia ; Cells, Cultured ; Disease Models, Animal ; Feedback, Physiological ; Infarction, Middle Cerebral Artery/enzymology ; Infarction, Middle Cerebral Artery/pathology ; Male ; Netrin-1/metabolism ; Neurons/metabolism ; Neurons/pathology ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer.
Autorzy :
Jin X; Department of Clinical Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Luan H; Department of Clinical Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Chai H; Department of Clinical Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Yan L; Department of Respiratory Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Zhang J; Department of Respiratory Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Wang Q; Department of Respiratory Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Cao L; Department of Respiratory Medicine, Τhe Second Hospital Affiliated to Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
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Źródło :
International journal of oncology [Int J Oncol] 2019 Apr; Vol. 54 (4), pp. 1457-1465. Date of Electronic Publication: 2019 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelial-Mesenchymal Transition*
Tumor Microenvironment*
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*pathology
Netrin-1/*metabolism
A549 Cells ; Carcinoma, Non-Small-Cell Lung/blood ; Cell Hypoxia ; Female ; Humans ; Lung Neoplasms/blood ; Male ; Middle Aged ; Netrin-1/blood ; Netrin-1/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/metabolism ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus.
Autorzy :
Prieto CP; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Casas BS; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Falcón P; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Villanueva A; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Lois P; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Lattus J; Campus Oriente, Department of Obstetrics and Gynecology, Faculty of Medicine, Universidad de Chile, Santiago de Chile 7800024, Chile. .
Palma V; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Mar 20; Vol. 20 (6). Date of Electronic Publication: 2019 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Human Umbilical Vein Endothelial Cells/*metabolism
Netrin-1/*metabolism
Receptors, Cell Surface/*metabolism
Diabetes, Gestational/genetics ; Diabetes, Gestational/metabolism ; Female ; Humans ; Neovascularization, Physiologic/genetics ; Neovascularization, Physiologic/physiology ; Netrin-1/genetics ; Pregnancy ; Receptors, Cell Surface/genetics ; Signal Transduction/genetics ; Signal Transduction/physiology ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
The microRNAs let-7 and miR-9 down-regulate the axon-guidance genes Ntn1 and Dcc during peripheral nerve regeneration.
Autorzy :
Wang X; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Chen Q; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Yi S; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Liu Q; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Zhang R; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Wang P; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Qian T; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China.
Li S; From the Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nanjing, Jiangsu 226001, China .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2019 Mar 08; Vol. 294 (10), pp. 3489-3500. Date of Electronic Publication: 2019 Jan 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DCC Receptor/*genetics
Down-Regulation/*genetics
MicroRNAs/*genetics
Nerve Regeneration/*genetics
Netrin-1/*genetics
Sciatic Nerve/*physiology
3' Untranslated Regions/genetics ; Animals ; Axon Guidance/genetics ; Base Sequence ; Cell Movement/genetics ; Ganglia, Spinal/cytology ; Humans ; Netrin-1/metabolism ; Neurons/cytology ; Neurons/metabolism ; Rats ; Sciatic Nerve/cytology ; Sciatic Nerve/injuries ; Sciatic Nerve/metabolism
Czasopismo naukowe
Tytuł :
"The One Who Guides" Nigral Neuron Migration.
Autorzy :
Awatramani R; Northwestern University, Department of Neurology, Chicago, IL 60611, USA. Electronic address: .
Lévesque M; Department of Psychiatry and Neurosciences, Faculty of Medicine, Université Laval, CERVO Brain Research Centre, 2601 Chemin de la Canardiere, Quebec, QC, Canada.
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Źródło :
Neuron [Neuron] 2020 Aug 19; Vol. 107 (4), pp. 595-596.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
GABAergic Neurons*
Substantia Nigra*
Axons ; Dopamine ; Netrin-1
Czasopismo naukowe
Tytuł :
SARS-CoV-2 orf1b Gene Sequence in the NTNG1 Gene on Human Chromosome 1.
Autorzy :
Lehrer S; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, U.S.A. .
Rheinstein PH; Severn Health Solutions, Severna Park, MD, U.S.A.
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2020 Jun; Vol. 34 (3 Suppl), pp. 1629-1632.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Genes, Viral*
Betacoronavirus/*genetics
Chromosomes, Human, Pair 1/*genetics
Exoribonucleases/*genetics
Netrin-1/*genetics
Viral Nonstructural Proteins/*genetics
Viral Proteins/*genetics
Animals ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Base Sequence ; Coronavirus Infections/drug therapy ; DNA, Complementary/genetics ; Endoribonucleases/genetics ; Haloperidol/analogs & derivatives ; Haloperidol/pharmacology ; Haloperidol/therapeutic use ; Humans ; Introns/genetics ; Pan troglodytes/genetics ; Pandemics ; Pneumonia, Viral/drug therapy ; RNA, Viral/genetics ; Schizophrenia/drug therapy ; Schizophrenia/genetics ; Sequence Alignment ; Sequence Homology, Nucleic Acid ; Species Specificity
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain.
Autorzy :
Zhu S; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Dr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, China.
Zhu J; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Orthopaedic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Zhen G; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hu Y; Department of Orthopaedic Surgery, Xiangya Hospital, Central South University, Changsha, China.
An S; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Orthopaedic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Li Y; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Orthopaedic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Zheng Q; Department of Neuroscience, Neurosurgery, and Dermatology, Center of Sensory Biology, Johns Hopkins University School of Medicine, Howard Hughes Medical Institute, Baltimore, Maryland, USA.
Chen Z; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yang Y; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wan M; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Skolasky RL; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Cao Y; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wu T; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gao B; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yang M; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gao M; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kuliwaba J; Department of Orthopaedics and Trauma, Royal Adelaide Hospital, University of Adelaide, Adelaide, Australia.
Ni S; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang L; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wu C; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Findlay D; Department of Orthopaedics and Trauma, Royal Adelaide Hospital, University of Adelaide, Adelaide, Australia.
Eltzschig HK; Department of Anesthesiology, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Ouyang HW; Dr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, China.; ZJU-UoE Joint Institute, School of Medicine, Zhejiang University, Hangzhou, China.
Crane J; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhou FQ; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Guan Y; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dong X; Department of Neuroscience, Neurosurgery, and Dermatology, Center of Sensory Biology, Johns Hopkins University School of Medicine, Howard Hughes Medical Institute, Baltimore, Maryland, USA.
Cao X; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2019 Mar 01; Vol. 129 (3), pp. 1076-1093. Date of Electronic Publication: 2019 Feb 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ganglia, Spinal/*metabolism
Netrin-1/*metabolism
Osteoarthritis/*metabolism
Osteoclasts/*metabolism
Pain/*metabolism
Sensory Receptor Cells/*metabolism
Animals ; Bone Remodeling/genetics ; DCC Receptor/genetics ; DCC Receptor/metabolism ; Ganglia, Spinal/pathology ; Male ; Mice ; Netrin-1/genetics ; Osteoarthritis/genetics ; Osteoarthritis/pathology ; Osteoclasts/pathology ; Pain/genetics ; Pain/pathology ; Sensory Receptor Cells/pathology
Czasopismo naukowe
Tytuł :
Netrin-1 plays a role in the effect of moderate exercise on myocardial fibrosis in rats.
Autorzy :
Daliang Z; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Lifang Y; Clinical Pharmacy, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China.
Hong F; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Lingling Z; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Lin W; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Dapeng L; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Tianshu Z; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
Weimin L; Department of Cardiology, First Hospital of Harbin City, Harbin, Heilongjiang Province, China.
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Źródło :
PloS one [PLoS One] 2019 Feb 21; Vol. 14 (2), pp. e0199802. Date of Electronic Publication: 2019 Feb 21 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endomyocardial Fibrosis/*metabolism
Myocardial Infarction/*metabolism
Netrin-1/*metabolism
Physical Conditioning, Animal/*physiology
Animals ; Cardiomyopathies/metabolism ; DCC Receptor/blood ; Endomyocardial Fibrosis/blood ; Fibrosis/metabolism ; Interleukin-6/blood ; Male ; Matrix Metalloproteinase 2/blood ; Matrix Metalloproteinase 9/blood ; Myocardial Infarction/blood ; Myocardium/metabolism ; Myocardium/pathology ; Netrin-1/blood ; Physical Conditioning, Animal/methods ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha/blood ; Ventricular Function, Left ; Ventricular Remodeling
Czasopismo naukowe
Tytuł :
Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells.
Autorzy :
Wu Z; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Makihara S; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada.
Yam PT; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
Teo S; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Renier N; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Balekoglu N; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada.
Moreno-Bravo JA; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Olsen O; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Chédotal A; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Charron F; Montreal Clinical Research Institute (IRCM), 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Division of Experimental Medicine, Department of Anatomy and Cell Biology, Department of Biology, McGill University, Montreal, QC H3A 2B2, Canada; Department of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada. Electronic address: .
Tessier-Lavigne M; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2019 Feb 20; Vol. 101 (4), pp. 635-647.e4. Date of Electronic Publication: 2019 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axon Guidance*
Cerebral Ventricles/*embryology
Hedgehog Proteins/*metabolism
Netrin-1/*metabolism
Neurons/*metabolism
Spinal Cord/*embryology
Animals ; Cells, Cultured ; Cerebral Ventricles/cytology ; Cerebral Ventricles/metabolism ; Female ; Hedgehog Proteins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Netrin-1/genetics ; Neurons/cytology ; Rats ; Rats, Sprague-Dawley ; Rhombencephalon/cytology ; Rhombencephalon/embryology ; Rhombencephalon/metabolism ; Spinal Cord/cytology ; Spinal Cord/metabolism
Czasopismo naukowe
Tytuł :
Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance.
Autorzy :
Moreno-Bravo JA; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Roig Puiggros S; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Mehlen P; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue,' LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
Chédotal A; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France. Electronic address: .
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Źródło :
Neuron [Neuron] 2019 Feb 20; Vol. 101 (4), pp. 625-634.e3. Date of Electronic Publication: 2019 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axon Guidance*
Cerebral Ventricles/*embryology
Netrin-1/*metabolism
Neurons/*metabolism
Rhombencephalon/*embryology
Spinal Cord/*embryology
Animals ; Cerebral Ventricles/cytology ; Cerebral Ventricles/metabolism ; Female ; Male ; Mice ; Netrin-1/genetics ; Neurons/cytology ; Rhombencephalon/cytology ; Rhombencephalon/metabolism ; Spinal Cord/cytology ; Spinal Cord/metabolism
Czasopismo naukowe

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