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Wyszukujesz frazę ""Neurodegenerative Diseases"" wg kryterium: Temat


Tytuł:
Transgenic Mouse Models for the Study of Neurodegenerative Diseases.
Autorzy:
Marín-Moreno A; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) - Consejo Superior de Investigaciones Científicas (CSIC), 28130 Valdeolmos, Spain.
Canoyra S; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) - Consejo Superior de Investigaciones Científicas (CSIC), 28130 Valdeolmos, Spain.
Fernández-Borges N; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) - Consejo Superior de Investigaciones Científicas (CSIC), 28130 Valdeolmos, Spain.
Espinosa JC; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) - Consejo Superior de Investigaciones Científicas (CSIC), 28130 Valdeolmos, Spain.
Torres JM; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) - Consejo Superior de Investigaciones Científicas (CSIC), 28130 Valdeolmos, Spain.
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Źródło:
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2023 Jan 19; Vol. 28 (1), pp. 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/genetics
Neurodegenerative Diseases*/therapy
Animals ; Mice ; Humans ; Cell Death ; Life Expectancy ; Mice, Transgenic ; Models, Animal
Czasopismo naukowe
Tytuł:
Targeting the Nrf2 signaling pathway using phytochemical ingredients: A novel therapeutic road map to combat neurodegenerative diseases.
Autorzy:
Bai X; Department of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, 110004, Shenyang, Liaoning, PR China.
Bian Z; Department of Otolaryngology Head and Neck Surgery, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, 110004, Shenyang, Liaoning, PR China.
Zhang M; Department of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, 110004, Shenyang, Liaoning, PR China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Jan; Vol. 109, pp. 154582. Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/metabolism
Alzheimer Disease*/drug therapy
Parkinson Disease*
Humans ; NF-E2-Related Factor 2/metabolism ; Signal Transduction ; Antioxidants/pharmacology ; Antioxidants/therapeutic use
Czasopismo naukowe
Tytuł:
Kynurenine-3-monooxygenase (KMO): From its biological functions to therapeutic effect in diseases progression.
Autorzy:
Chen Y; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Zhang J; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Yang Y; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Xiang K; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Li H; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.; College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Sun D; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Chen L; Key Laboratory of Structure-Based Drug Design & Discovery, Wuya College of Innovation, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2022 Dec; Vol. 237 (12), pp. 4339-4355. Date of Electronic Publication: 2022 Sep 11.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Kynurenine 3-Monooxygenase*/chemistry
Kynurenine 3-Monooxygenase*/metabolism
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/metabolism
Humans ; Disease Progression ; Kynurenic Acid/metabolism ; Kynurenine/metabolism ; Tryptophan/metabolism
Czasopismo naukowe
Tytuł:
Targeting epigenetics as a promising therapeutic strategy for treatment of neurodegenerative diseases.
Autorzy:
Zhang L; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China. Electronic address: .
Liu Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Lu Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Wang G; State Key Laboratory of Biotherapy and Cancer Center, Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China. Electronic address: .
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Źródło:
Biochemical pharmacology [Biochem Pharmacol] 2022 Dec; Vol. 206, pp. 115295. Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/genetics
Humans ; Epigenesis, Genetic ; DNA Methylation ; Histones/metabolism ; Chromatin Assembly and Disassembly
Czasopismo naukowe
Tytuł:
A systematic review on the risk of neurodegenerative diseases and neurocognitive disorders in professional and varsity athletes.
Autorzy:
Bellomo G; National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. .
Piscopo P; Department of Neurosciences, Italian National Institute of Health, Rome, Italy.
Corbo M; Department of Neurorehabilitation Sciences, Casa Cura Policlinico, Milan, Italy.
Pupillo E; Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Stipa G; Clinical Neurophysiology Division, Neuroscience Department, S. Maria University Hospital, Terni, Italy.
Beghi E; Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Vanacore N; National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
Lacorte E; National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2022 Dec; Vol. 43 (12), pp. 6667-6691. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/epidemiology
Amyotrophic Lateral Sclerosis*/complications
Chronic Traumatic Encephalopathy*/epidemiology
Chronic Traumatic Encephalopathy*/diagnosis
Cognitive Dysfunction*/epidemiology
Cognitive Dysfunction*/complications
Dementia*/complications
Football*
Neurodegenerative Diseases*/epidemiology
Neurodegenerative Diseases*/complications
Parkinson Disease*/complications
Humans ; Athletes
Czasopismo naukowe
Tytuł:
Apelin/APJ system: an emerging therapeutic target for neurological diseases.
Autorzy:
Li A; Institute of Pharmacy and Pharmacology, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Zhao Q; Health Management Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chen L; Institute of Pharmacy and Pharmacology, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. .
Li Z; Department of Orthopedics, Third Xiangya Hospital of Central South University, Changsha, Hunan, China. .
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Źródło:
Molecular biology reports [Mol Biol Rep] 2023 Feb; Vol. 50 (2), pp. 1639-1653. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*
Brain Injuries*
Humans ; Apelin/metabolism ; Apelin Receptors/metabolism ; Oxidative Stress ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł:
The role of ferroptosis in neurodegenerative diseases.
Autorzy:
Xu Y; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China.; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China.
Zhao J; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Zhao Y; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China.; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China.
Zhou L; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China.; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China.
Qiao H; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China.; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China.
Xu Q; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China.; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China.
Liu Y; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China. .; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, Hunan, China. .; National Medicine Functional Experimental Teaching Center, Central South University, Changsha, 410078, Hunan, China. .
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Źródło:
Molecular biology reports [Mol Biol Rep] 2023 Feb; Vol. 50 (2), pp. 1655-1661. Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*
Ferroptosis*/genetics
Humans ; Apoptosis ; Cell Death ; Oxidative Stress/physiology
Czasopismo naukowe
Tytuł:
Resveratrol, Endocrine Disrupting Chemicals, Neurodegenerative Diseases and Depression: Genes, Transcription Factors, microRNAs, and Sponges Involved.
Autorzy:
Nguyen HD; Department of Pharmacy, College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea. .
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Źródło:
Neurochemical research [Neurochem Res] 2023 Feb; Vol. 48 (2), pp. 604-624. Date of Electronic Publication: 2022 Oct 16.
Typ publikacji:
Journal Article
MeSH Terms:
Endocrine Disruptors*
Neurodegenerative Diseases*/chemically induced
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/genetics
Amyotrophic Lateral Sclerosis*
MicroRNAs*/genetics
MicroRNAs*/metabolism
Parkinson Disease*/genetics
Humans ; Resveratrol ; Transcription Factors ; Brain-Derived Neurotrophic Factor ; Cyclooxygenase 2 ; Depression/chemically induced ; Depression/drug therapy ; Interleukin-6
Czasopismo naukowe
Tytuł:
PINK1/Parkin-mediated mitophagy in neurodegenerative diseases.
Autorzy:
Li J; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Yang D; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Li Z; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Zhao M; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Wang D; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Sun Z; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Wen P; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Dai Y; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Gou F; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Ji Y; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Zhao D; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China.
Yang L; National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, China. Electronic address: .
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Źródło:
Ageing research reviews [Ageing Res Rev] 2023 Feb; Vol. 84, pp. 101817. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mitophagy*
Neurodegenerative Diseases*/enzymology
Protein Kinases*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Humans
Czasopismo naukowe
Tytuł:
Radon exposure and risk of neurodegenerative diseases among male miners in Ontario, Canada: A cohort study.
Autorzy:
Zeng X; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.; Occupational and Environmental Health Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Berriault C; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.
Arrandale VH; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.; Occupational and Environmental Health Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
DeBono NL; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.; Occupational and Environmental Health Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Harris MA; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.; Occupational and Environmental Health Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; School of Occupational and Public Health, Toronto Metropolitan University, Toronto, Ontario, Canada.
Demers PA; Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada.; Occupational and Environmental Health Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
American journal of industrial medicine [Am J Ind Med] 2023 Feb; Vol. 66 (2), pp. 132-141. Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/epidemiology
Neurodegenerative Diseases*/etiology
Parkinson Disease*
Alzheimer Disease*/complications
Lung Neoplasms*/epidemiology
Radon*/adverse effects
Occupational Exposure*/adverse effects
Occupational Diseases*/epidemiology
Occupational Diseases*/etiology
Neoplasms, Radiation-Induced*
Humans ; Male ; Cohort Studies ; Ontario/epidemiology
Czasopismo naukowe
Tytuł:
Subclinical peripheral neuropathy is common in neuronal intranuclear inclusion disease with dominant encephalopathy.
Autorzy:
Hong D; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Medical Genetics, First Affiliated Hospital of Nanchang University, Nanchang, China.
Wang H; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Zhu M; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Medical Genetics, First Affiliated Hospital of Nanchang University, Nanchang, China.
Peng Y; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Medical Genetics, First Affiliated Hospital of Nanchang University, Nanchang, China.
Huang P; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.
Zheng Y; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yu M; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Meng L; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Li F; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Yu J; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Zhou M; Department of Neurology, First Affiliated Hospital of Nanchang University, Nanchang, China.
Deng J; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Wang Z; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
Yuan Y; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.
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Źródło:
European journal of neurology [Eur J Neurol] 2023 Feb; Vol. 30 (2), pp. 527-537. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/complications
Neurodegenerative Diseases*/genetics
Brain Diseases*
Peripheral Nervous System Diseases*/genetics
Peripheral Nervous System Diseases*/pathology
Humans ; Intranuclear Inclusion Bodies/genetics ; Intranuclear Inclusion Bodies/pathology
SCR Disease Name:
Neuronal intranuclear inclusion disease
Czasopismo naukowe
Tytuł:
PEBAT, an Intriguing Neurodegenerative Tubulinopathy Caused by a Novel Homozygous Variant in TBCD: A Case Series and Literature Review.
Autorzy:
Ocampo-Chih C; Monroe Carell Jr. Children's Hospital, Vanderbilt University, Nashville, Tennessee.
Dennis H; Department of Medical Genetics, Emory University School of Medicine, Atlanta, Georgia.
Lall N; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Department of Radiology, Emory University School of Medicine, Atlanta, Georgia.
Pham N; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Department of Pediatric Critical Care Medicine, Emory University School of Medicine, Atlanta, Georgia.
Liang B; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia.
Verma S; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Department of Neurology, Emory University School of Medicine, Atlanta, Georgia.
Neira Fresneda J; Department of Medical Genetics, Emory University School of Medicine, Atlanta, Georgia. Electronic address: .
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Źródło:
Pediatric neurology [Pediatr Neurol] 2023 Feb; Vol. 139, pp. 59-64. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Neurodegenerative Diseases*/complications
Neurodegenerative Diseases*/diagnostic imaging
Neurodegenerative Diseases*/genetics
Brain Diseases*/pathology
Infant ; Humans ; Tubulin/genetics ; Tubulin/metabolism ; Microtubule-Associated Proteins/genetics
Czasopismo naukowe
Tytuł:
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Autorzy:
Turkez H; Department of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Altay O; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address: .
Yildirim S; Department of Pathology, Veterinary Faculty, Ataturk University, Erzurum, Turkey. Electronic address: .
Li X; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address: .
Yang H; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address: .
Bayram C; Department of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Bolat I; Department of Pathology, Veterinary Faculty, Ataturk University, Erzurum, Turkey. Electronic address: .
Oner S; Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Tozlu OO; Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey. Electronic address: .
Arslan ME; Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Arif M; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address: .
Yulug B; Department of Neurology and Neuroscience, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Hanoglu L; Department of Neurology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey. Electronic address: .
Cankaya S; Department of Neurology and Neuroscience, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Lam S; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address: .
Velioglu HA; Functional Imaging and Cognitive-Affective Neuroscience Lab, Istanbul Medipol University, Istanbul, Turkey; Department of Women's and Children's Health, Karolinska Institute, Neuroimaging Lab, Stockholm, Sweden.
Coskun E; Department of Neurology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Idil E; Department of Neurology and Neuroscience, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Nogaylar R; Department of Neurology and Neuroscience, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Ozsimsek A; Department of Neurology and Neuroscience, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey. Electronic address: .
Hacimuftuoglu A; Department of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Shoaie S; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address: .
Zhang C; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, PR China. Electronic address: .
Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden. Electronic address: .
Borén J; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address: .
Uhlén M; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address: .
Mardinoglu A; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Feb 01; Vol. 314, pp. 121325. Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/metabolism
Parkinson Disease*/metabolism
Alzheimer Disease*/metabolism
Humans ; Animals ; Rats ; Mitochondria/metabolism ; Models, Animal ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Spatially informed Bayesian neural network for neurodegenerative diseases classification.
Autorzy:
Payares-Garcia D; ITC Faculty Geo-Information Science and Earth Observation, University of Twente, Enschede.; Institute for Geoinformatics, University of Münster, Münster, Germany.
Mateu J; Department of Mathematics, University Jaume I, Castellón de la Plana, Castellón, Spain.
Schick W; Institute for Geoinformatics, University of Münster, Münster, Germany.
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Źródło:
Statistics in medicine [Stat Med] 2023 Jan 30; Vol. 42 (2), pp. 105-121. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/diagnostic imaging
Alzheimer Disease*/diagnostic imaging
Alzheimer Disease*/pathology
Humans ; Bayes Theorem ; Neural Networks, Computer ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł:
SERS "hot spot" enhance-array assay for misfolded SOD1 correlated with white matter lesions and aging.
Autorzy:
Gao F; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China.
Sun J; Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, 250021, China.
Yao M; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China.
Song Y; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China; Medical College of Qingdao University, Qingdao, 266021, China.
Yi H; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China.
Yang M; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China.
Ni Q; Postdoctoral Workstation, Taian Central Hospital, Taian, 271000, Shandong, China.
Kong J; Department of Human Anatomy and Cell Science, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, MB, Canada.
Yuan H; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China. Electronic address: .
Sun B; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China. Electronic address: .
Wang Y; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong, 271000, China. Electronic address: .
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Źródło:
Analytica chimica acta [Anal Chim Acta] 2023 Jan 15; Vol. 1238, pp. 340163. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/diagnosis
Neurodegenerative Diseases*/genetics
Neurodegenerative Diseases*/metabolism
Superoxide Dismutase-1*/analysis
Superoxide Dismutase-1*/genetics
Superoxide Dismutase-1*/metabolism
White Matter*/metabolism
White Matter*/physiopathology
Proteostasis Deficiencies*/diagnosis
Proteostasis Deficiencies*/genetics
Proteostasis Deficiencies*/metabolism
Humans ; Antibodies ; Gold ; Reproducibility of Results ; Superoxide Dismutase
Czasopismo naukowe
Tytuł:
A Promising Strategy to Treat Neurodegenerative Diseases by SIRT3 Activation.
Autorzy:
Tyagi A; Rocky Mountain Regional VA Medical Center, Aurora, CO 80045, USA.; Department of Medicine, University of Colorado-Anschutz Medical Campus, Aurora, CO 80045, USA.
Pugazhenthi S; Rocky Mountain Regional VA Medical Center, Aurora, CO 80045, USA.; Department of Medicine, University of Colorado-Anschutz Medical Campus, Aurora, CO 80045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 13; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Metabolic Syndrome*/genetics
Metabolic Syndrome*/metabolism
Neurodegenerative Diseases*/genetics
Neurodegenerative Diseases*/metabolism
Sirtuin 3*/genetics
Sirtuin 3*/metabolism
Humans ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł:
Microtubule-Stabilizing 1,2,4-Triazolo[1,5- a ]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Autorzy:
Alle T; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Varricchio C; Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF103NB, U.K.
Yao Y; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce St., Philadelphia, Pennsylvania 19104, United States.
Lucero B; Department of Chemistry & Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Nzou G; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce St., Philadelphia, Pennsylvania 19104, United States.
Demuro S; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Muench M; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce St., Philadelphia, Pennsylvania 19104, United States.
Vuong KD; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Oukoloff K; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Cornec AS; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, 231 South 34th St., Philadelphia, Pennsylvania 19104-6323, United States.
Francisco KR; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Caffrey CR; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Lee VM; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce St., Philadelphia, Pennsylvania 19104, United States.
Smith AB 3rd; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, 231 South 34th St., Philadelphia, Pennsylvania 19104-6323, United States.
Brancale A; Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF103NB, U.K.
Brunden KR; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce St., Philadelphia, Pennsylvania 19104, United States.
Ballatore C; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Jan 12; Vol. 66 (1), pp. 435-459. Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/metabolism
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Humans ; Pyrimidines/chemistry ; Microtubules/metabolism ; Tubulin/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Machine learning for predicting neurodegenerative diseases in the general older population: a cohort study.
Autorzy:
Aguayo GA; Deep Digital Phenotyping Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg. .
Zhang L; Bioinformatics Platform, Luxembourg Institute of Health, Strassen, Luxembourg.
Vaillant M; Competence Center for Methodology and Statistics, Translational Medicine Operations Hub, Luxembourg Institute of Health, Strassen, Luxembourg.
Ngari M; Competence Center for Methodology and Statistics, Translational Medicine Operations Hub, Luxembourg Institute of Health, Strassen, Luxembourg.; KEMRI/Wellcome Trust Research Programme, Kilifi, Kenya.
Perquin M; Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Moran V; Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.; Living Conditions Department, Luxembourg Institute of Socio-Economic Research, Esch-Sur-Alzette, Luxembourg.
Huiart L; Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Krüger R; LCSB, Luxembourg Centre for System Biomedicine, University of Luxembourg, Esch-Sur-Alzette, Luxembourg.; Parkinson Research Clinic, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.; Transversal Translational Medicine, Luxembourg Institute of Health, Strassen, Luxembourg.
Azuaje F; Bioinformatics Platform, Luxembourg Institute of Health, Strassen, Luxembourg.; Genomics England, London, UK.
Ferdynus C; Methodological Support Unit, Félix Guyon University Hospital Center, Saint-Denis, La Réunion, France.
Fagherazzi G; Deep Digital Phenotyping Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
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Źródło:
BMC medical research methodology [BMC Med Res Methodol] 2023 Jan 11; Vol. 23 (1), pp. 8. Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/diagnosis
Neurodegenerative Diseases*/epidemiology
Male ; Humans ; Female ; Middle Aged ; Aged ; Cohort Studies ; Longitudinal Studies ; Machine Learning ; Neural Networks, Computer
Czasopismo naukowe
Tytuł:
Ribosome biogenesis in disease: new players and therapeutic targets.
Autorzy:
Jiao L; Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, Jiangsu, 215123, P. R. China.
Liu Y; Department of Orthopedics, the Second Hospital of Jilin University, Changchun, Jilin, 130000, P. R. China.
Yu XY; Key Laboratory of Molecular Target & Clinical Pharmacology and the NMPA State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, 511436, P. R. China.
Pan X; Department of Structural Heart Disease, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China.; Key Laboratory of Cardiovascular Appratus Innovation, Beijing, 100037, P. R. China.
Zhang Y; Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, Jiangsu, 215123, P. R. China.
Tu J; Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, Jiangsu, 215123, P. R. China.
Song YH; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, Soochow University, National Clinical Research Center for Hematologic Diseases, the First Affiliated Hospital of Soochow University, Suzhou, P. R. China. yaohua_.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, 215123, P. R. China. yaohua_.
Li Y; Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, Jiangsu, 215123, P. R. China. yangxin_.
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Źródło:
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2023 Jan 09; Vol. 8 (1), pp. 15. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/genetics
Neurodegenerative Diseases*/metabolism
COVID-19*/metabolism
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Pregnancy ; Female ; COVID-19 Vaccines/metabolism ; Ribosomes/genetics ; Ribosomal Proteins/genetics ; RNA, Untranslated ; Mechanistic Target of Rapamycin Complex 1/metabolism
Czasopismo naukowe
Tytuł:
Zebrafish: A Model Deciphering the Impact of Flavonoids on Neurodegenerative Disorders.
Autorzy:
Mhalhel K; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
Sicari M; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
Pansera L; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
Chen J; Institute of Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology (KIT), Campus North, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Levanti M; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
Diotel N; Université de la Réunion, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), Plateforme CYROI, F-97490 Sainte-Clotilde, France.
Rastegar S; Institute of Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology (KIT), Campus North, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Germanà A; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
Montalbano G; Zebrafish Neuromorphology Lab., Department of Veterinary Sciences, University of Messina, Via Giovanni Palatucci snc, 98168 Messina, Italy.
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Źródło:
Cells [Cells] 2023 Jan 07; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Neurodegenerative Diseases*/metabolism
Parkinson Disease*/metabolism
Humans ; Animals ; Zebrafish/metabolism ; Flavonoids/pharmacology ; Flavonoids/therapeutic use ; Brain/metabolism
Czasopismo naukowe

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