Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Neurogenesis"" wg kryterium: Temat


Tytuł :
TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment.
Autorzy :
Montibus B; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.; King's College, London, UK.
Cercy J; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Bouschet T; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Charras A; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.; Department of Women's and Children's Health, Institute of Lifecourse and Medical Sciences, Liverpool University, Liverpool, UK.
Maupetit-Méhouas S; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Nury D; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Gonthier-Guéret C; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Chauveau S; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Allegre N; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Chariau C; Nantes Université, CHU Nantes, SFR Santé, FED4203, Inserm UMS 016, CNRS UMS 3556, 44000, Nantes, France.
Hong CC; Vanderbilt University School of Medicine Nashville, Nashville, USA.
Vaillant I; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France.
Marques CJ; Life and Health Sciences Research Institute (ICVS), University of Minho, Campus de Gualtar, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.; Department of Genetics, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Porto, Portugal.
Court F; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France. .
Arnaud P; Université Clermont Auvergne, CNRS, Inserm, GReD, 63000, Clermont-Ferrand, France. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Jan; Vol. 78 (2), pp. 757-768. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Neurogenesis*
Dioxygenases/*metabolism
Embryonic Stem Cells/*cytology
Jumonji Domain-Containing Histone Demethylases/*genetics
5-Methylcytosine/analogs & derivatives ; 5-Methylcytosine/metabolism ; Animals ; Cells, Cultured ; Dioxygenases/genetics ; Embryonic Stem Cells/metabolism ; Epigenesis, Genetic ; Gene Knockdown Techniques ; Mice, Inbred C57BL ; Promoter Regions, Genetic ; Up-Regulation
Czasopismo naukowe
Tytuł :
LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis.
Autorzy :
Hu HB; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Song ZQ; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Song GP; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Li S; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Tu HQ; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Wu M; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Zhang YC; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Yuan JF; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Li TT; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Li PY; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Xu YL; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Shen XL; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Han QY; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Li AL; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Zhou T; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China.
Chun J; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA.
Zhang XM; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China. .
Li HY; State Key Laboratory of Proteomics, National Center of Biomedical Analysis, Beijing, China. .; School of Basic Medical Sciences, Fudan University, Shanghai, China. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Jan 28; Vol. 12 (1), pp. 662. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Cilia/*drug effects
Lysophospholipids/*pharmacology
Neurogenesis/*drug effects
Retinal Pigment Epithelium/*drug effects
Animals ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cilia/genetics ; Cilia/metabolism ; HEK293 Cells ; Heterotrimeric GTP-Binding Proteins/metabolism ; Humans ; Lysophospholipids/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Neural Stem Cells/cytology ; Neural Stem Cells/drug effects ; Neural Stem Cells/metabolism ; Neurogenesis/genetics ; Protein Binding ; RNA Interference ; Receptors, Lysophosphatidic Acid/genetics ; Receptors, Lysophosphatidic Acid/metabolism ; Retinal Pigment Epithelium/cytology ; Retinal Pigment Epithelium/metabolism
Czasopismo naukowe
Tytuł :
Mapping the molecular and cellular complexity of cortical malformations.
Autorzy :
Klingler E; Department of Basic Neurosciences, University of Geneva, CH-1202 Geneva, Switzerland.
Francis F; INSERM U 1270, F-75005 Paris, France.; Sorbonne University, UMR-S 1270, F-75005 Paris, France.; Institut du Fer à Moulin, F-75005 Paris, France.
Jabaudon D; Department of Basic Neurosciences, University of Geneva, CH-1202 Geneva, Switzerland. .; Clinic of Neurology, Geneva University Hospital, 1211 Geneva, Switzerland.
Cappello S; Max Planck Institute of Psychiatry, 80804 Munich, Germany. .
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2021 Jan 22; Vol. 371 (6527).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cerebral Cortex/*abnormalities
Mental Disorders/*metabolism
Nervous System Diseases/*metabolism
Neurogenesis/*physiology
Neurons/*physiology
Animals ; Behavior ; Cell Movement/genetics ; Cell Movement/physiology ; Cerebral Cortex/metabolism ; Cerebral Cortex/ultrastructure ; Gene Expression Regulation, Developmental ; Humans ; Mental Disorders/genetics ; Mice ; Nervous System Diseases/genetics ; Neural Pathways/abnormalities ; Neural Pathways/metabolism ; Neural Pathways/ultrastructure ; Neurogenesis/genetics ; Neurons/cytology ; Organ Specificity/genetics ; Organ Specificity/physiology
Czasopismo naukowe
Tytuł :
Making sense of neural development by comparing wiring strategies for seeing and hearing.
Autorzy :
Sitko AA; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
Goodrich LV; Department of Neurobiology, Harvard Medical School, Boston, MA, USA. .
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2021 Jan 08; Vol. 371 (6525).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Neurogenesis*
Auditory Pathways/*embryology
Cochlear Nucleus/*embryology
Retina/*embryology
Visual Pathways/*embryology
Animals ; Hearing/physiology ; Mice ; Sensory Receptor Cells/ultrastructure ; Synapses/ultrastructure ; Vision, Ocular/physiology
Czasopismo naukowe
Tytuł :
Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's Disease, Depression, Schizophrenia and Ionizing Radiation Exposure.
Autorzy :
Segaran RC; Radiation Physiology Lab, Singapore Nuclear Research and Safety Initiative, National University of Singapore, CREATE Tower, Singapore 138602, Singapore.
Chan LY; Radiation Physiology Lab, Singapore Nuclear Research and Safety Initiative, National University of Singapore, CREATE Tower, Singapore 138602, Singapore.
Wang H; Radiation Physiology Lab, Singapore Nuclear Research and Safety Initiative, National University of Singapore, CREATE Tower, Singapore 138602, Singapore.
Sethi G; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.
Tang FR; Radiation Physiology Lab, Singapore Nuclear Research and Safety Initiative, National University of Singapore, CREATE Tower, Singapore 138602, Singapore.
Pokaż więcej
Źródło :
Current medicinal chemistry [Curr Med Chem] 2021; Vol. 28 (1), pp. 19-52.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Alzheimer Disease*/genetics
Depression*/genetics
MicroRNAs*/genetics
Neurogenesis*
Schizophrenia*/genetics
Radiation Exposure/*adverse effects
Biomarkers ; Humans ; Radiation, Ionizing
Czasopismo naukowe
Tytuł :
Neuronal lineages derived from the nerve-associated Schwann cell precursors.
Autorzy :
Kameneva P; Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, 171 77, Sweden.
Kastriti ME; Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, 171 77, Sweden.; Department of Molecular Neurosciences, Center for Brain Research, Medical University Vienna, Vienna, 1090, Austria.
Adameyko I; Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, 171 77, Sweden. .; Department of Molecular Neurosciences, Center for Brain Research, Medical University Vienna, Vienna, 1090, Austria. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Jan; Vol. 78 (2), pp. 513-529. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neurogenesis*
Neurons/*cytology
Schwann Cells/*cytology
Stem Cells/*cytology
Animals ; Chromaffin Cells/cytology ; Chromaffin Cells/metabolism ; Humans ; Neurons/metabolism ; Peripheral Nervous System/cytology ; Peripheral Nervous System/metabolism ; Schwann Cells/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
[Chinese medicine Buyang Huanwu decoction promotes neurogenesis and angiogenesis in ischemic stroke rats by upregulating miR-199a-5p expression].
Autorzy :
Zhuge L; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Fang Y; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jin H; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Li L; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yang Y; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Hu X; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Chu L; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Pokaż więcej
Źródło :
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences [Zhejiang Da Xue Xue Bao Yi Xue Ban] 2020 Dec 25; Vol. 49 (6), pp. 687-696.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Ischemic Stroke*/drug therapy
MicroRNAs*/genetics
Neurogenesis*/drug effects
Up-Regulation*/drug effects
Animals ; Brain Ischemia/drug therapy ; Male ; Rats ; Rats, Sprague-Dawley ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł :
Cannabinoid Type 1 Receptor is Undetectable in Rodent and Primate Cerebral Neural Stem Cells but Participates in Radial Neuronal Migration.
Autorzy :
Morozov YM; Department of Neuroscience, Kavli Institute for Neuroscience, Yale School of Medicine, Yale University, New Haven, CT 6510, USA.
Mackie K; Gill Center for Biomolecular Science, Indiana University, Bloomington, IN 47405-2204, USA.; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405-2204, USA.
Rakic P; Department of Neuroscience, Kavli Institute for Neuroscience, Yale School of Medicine, Yale University, New Haven, CT 6510, USA.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 17; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement*
Cell Proliferation*
Neurogenesis*
Neural Stem Cells/*metabolism
Neurons/*metabolism
Receptor, Cannabinoid, CB1/*metabolism
Animals ; Macaca mulatta ; Mice ; Mice, Knockout ; Neural Stem Cells/cytology ; Neurons/cytology ; Receptor, Cannabinoid, CB1/genetics
Czasopismo naukowe
Tytuł :
Metformin alleviates memory and hippocampal neurogenesis decline induced by methotrexate chemotherapy in a rat model.
Autorzy :
Sritawan N; Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Prajit R; Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Chaisawang P; Faculty of Medical Science, Nakhonratchasima College, Nakhon Ratchasima 30000, Thailand. Electronic address: .
Sirichoat A; Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Pannangrong W; Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Wigmore P; School of Life Sciences, Medical School, Queen's Medical Centre, Nottingham University, Nottingham NG7 2RD, UK. Electronic address: .
Welbat JU; Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Neuroscience Research and Development Group, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Pokaż więcej
Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Nov; Vol. 131, pp. 110651. Date of Electronic Publication: 2020 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Hippocampus/*drug effects
Memory Disorders/*drug therapy
Metformin/*therapeutic use
Methotrexate/*toxicity
Neurogenesis/*drug effects
Animals ; Antimetabolites, Antineoplastic/toxicity ; Hippocampus/pathology ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Male ; Memory Disorders/pathology ; Metformin/pharmacology ; Neurogenesis/physiology ; Random Allocation ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells.
Autorzy :
Asrican B; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Wooten J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Genetics and Molecular Biology Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Li YD; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Quintanilla L; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Zhang F; Department of Human Genetics, Emory University, Atlanta, GA 30322, USA.
Wander C; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Pharmacology Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Bao H; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Yeh CY; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Luo YJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Olsen R; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Lim SA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Hu J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Jin P; Department of Human Genetics, Emory University, Atlanta, GA 30322, USA.
Song J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .
Pokaż więcej
Źródło :
Neuron [Neuron] 2020 Oct 28; Vol. 108 (2), pp. 349-366.e6. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Astrocytes/*physiology
Cholecystokinin/*physiology
Dentate Gyrus/*physiology
Interneurons/*physiology
Neural Stem Cells/*physiology
Neuropeptides/*physiology
Animals ; Female ; Male ; Membrane Potentials ; Mice, Inbred C57BL ; Mice, Transgenic ; Signal Transduction
Czasopismo naukowe
Tytuł :
Metabolic tuning of inhibition regulates hippocampal neurogenesis in the adult brain.
Autorzy :
Wang X; Department of Neurobiology & Behavior, State University of New York at Stony Brook, Stony Brook, NY 11794.
Liu H; Department of Neurobiology & Behavior, State University of New York at Stony Brook, Stony Brook, NY 11794.
Morstein J; Department of Chemistry, New York University, New York, NY 10003.
Novak AJE; Department of Chemistry, New York University, New York, NY 10003.
Trauner D; Department of Chemistry, New York University, New York, NY 10003.
Xiong Q; Department of Neurobiology & Behavior, State University of New York at Stony Brook, Stony Brook, NY 11794; .
Yu Y; State Key Laboratory of Medical Neurobiology, School of Life Science, Fudan University, 200433 Shanghai, China; .; Human Phenome Institute, Fudan University, 200433 Shanghai, China.; Research Institute of Intelligent and Complex Systems, Fudan University, 200433 Shanghai, China.; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, 200433 Shanghai, China.
Ge S; Department of Neurobiology & Behavior, State University of New York at Stony Brook, Stony Brook, NY 11794; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 13; Vol. 117 (41), pp. 25818-25829. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Hippocampus/*metabolism
Animals ; Brain/growth & development ; Brain/metabolism ; Female ; Hippocampus/chemistry ; Hippocampus/cytology ; Lipid Metabolism ; Lysophospholipids/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Models, Theoretical ; Neuronal Plasticity ; Neurons/cytology ; Neurons/metabolism ; Sphingosine/analogs & derivatives ; Sphingosine/metabolism
Czasopismo naukowe
Tytuł :
Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.
Autorzy :
Hargrove-Grimes P; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Institute of Biomedical Sciences, George Washington University, Washington, District of Columbia, United States of America.
Mondal AK; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Gumerson J; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Nellissery J; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Aponte AM; Proteomics Core, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Gieser L; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Qian H; Visual Function Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Fariss RN; Biological Imaging Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Bonifacino JS; Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute for Child Health and Development, National Institutes of Health, Bethesda, Maryland, United States of America.
Li T; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Swaroop A; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Pokaż więcej
Źródło :
PLoS genetics [PLoS Genet] 2020 Dec 23; Vol. 16 (12), pp. e1009259. Date of Electronic Publication: 2020 Dec 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Autophagy*
Endocytosis*
Neurogenesis*
Guanine Nucleotide Exchange Factors/*genetics
Photoreceptor Cells/*metabolism
Retinal Degeneration/*metabolism
Animals ; Female ; Guanine Nucleotide Exchange Factors/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Photoreceptor Cells/cytology ; Retinal Degeneration/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis.
Autorzy :
Farooq M; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.; Department of Biochemistry and Biotechnology, The Islamia University of Bahawalpur, Baghdad ul Jadeed Campus, 63100, Bahawalpur, Punjab, Pakistan.
Lindbæk L; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Krogh N; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Doganli C; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Keller C; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Mönnich M; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Gonçalves AB; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Sakthivel S; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Mang Y; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Fatima A; Human Molecular Genetics Laboratory; Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering PIEAS, Jhang Road, 38000, Faisalabad, Punjab, Pakistan.
Andersen VS; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Hussain MS; Institute of Biochemistry I, University of Cologne, Joseph-Stelzmann-Strasse 52, D50931, Cologne, Germany.; Cologne Center for Genomics and Center for Molecular Medicine Cologne, University of Cologne, Robert-Koch-Strasse 21, D50931, Cologne, Germany.
Eiberg H; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Hansen L; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Kjaer KW; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Gopalakrishnan J; Institute of Human Genetics, Universitätsstrasse 1, Heinrich-Heine-University, D-40225, Düsseldorf, Germany.
Pedersen LB; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Møllgård K; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Nielsen H; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Baig SM; Human Molecular Genetics Laboratory; Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering PIEAS, Jhang Road, 38000, Faisalabad, Punjab, Pakistan.
Tommerup N; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark.
Christensen ST; Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark. .
Larsen LA; Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200, Copenhagen, Denmark. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Nov 16; Vol. 11 (1), pp. 5816. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Organelle Biogenesis*
Cilia/*metabolism
Microcephaly/*genetics
RNA-Binding Proteins/*genetics
Ribosomes/*metabolism
Adult ; Animals ; Base Sequence ; Brain/embryology ; Brain/pathology ; Cell Cycle ; Cell Nucleolus/metabolism ; Centrosome/metabolism ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Humans ; Male ; Mice ; Mutation/genetics ; Neural Stem Cells/metabolism ; Nuclear Proteins/metabolism ; Pakistan ; Pedigree ; Protein Binding ; RNA Processing, Post-Transcriptional ; RNA, Ribosomal/genetics ; RNA-Binding Proteins/metabolism ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Apigenin as a Candidate Prenatal Treatment for Trisomy 21: Effects in Human Amniocytes and the Ts1Cje Mouse Model.
Autorzy :
Guedj F; Prenatal Genomics and Therapy Section, Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA; Mother Infant Research Institute, Tufts Medical Center and Tufts Children's Hospital, Boston, MA 02111, USA. Electronic address: .
Siegel AE; Prenatal Genomics and Therapy Section, Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA; Mother Infant Research Institute, Tufts Medical Center and Tufts Children's Hospital, Boston, MA 02111, USA.
Pennings JLA; Center for Health Protection, National Institute for Public Health and the Environment, Bilthoven, BA 3720, the Netherlands.
Alsebaa F; Mother Infant Research Institute, Tufts Medical Center and Tufts Children's Hospital, Boston, MA 02111, USA.
Massingham LJ; Mother Infant Research Institute, Tufts Medical Center and Tufts Children's Hospital, Boston, MA 02111, USA.
Tantravahi U; Department of Pathology, Women and Infants' Hospital, Providence, RI 02912, USA.
Bianchi DW; Prenatal Genomics and Therapy Section, Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA; Mother Infant Research Institute, Tufts Medical Center and Tufts Children's Hospital, Boston, MA 02111, USA. Electronic address: .
Pokaż więcej
Źródło :
American journal of human genetics [Am J Hum Genet] 2020 Nov 05; Vol. 107 (5), pp. 911-931. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Apigenin/*pharmacology
Down Syndrome/*drug therapy
Gene Expression Regulation, Developmental/*drug effects
Neurogenesis/*drug effects
Spatial Memory/*drug effects
Stem Cells/*drug effects
Amniotic Fluid/cytology ; Amniotic Fluid/metabolism ; Animals ; Cytokines/genetics ; Cytokines/immunology ; Disease Models, Animal ; Down Syndrome/genetics ; Down Syndrome/immunology ; Down Syndrome/pathology ; Exploratory Behavior/drug effects ; Female ; Fetus ; Hippocampus/drug effects ; Hippocampus/immunology ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Interleukin-7/genetics ; Interleukin-7/immunology ; Ki-67 Antigen/genetics ; Ki-67 Antigen/immunology ; Male ; Mice ; Nestin/genetics ; Nestin/immunology ; Neurogenesis/genetics ; Oxidative Stress/drug effects ; PAX6 Transcription Factor/genetics ; PAX6 Transcription Factor/immunology ; Pregnancy ; Primary Cell Culture ; SOXB1 Transcription Factors/genetics ; SOXB1 Transcription Factors/immunology ; Sex Factors ; Stem Cells/metabolism ; Stem Cells/pathology ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/immunology
Czasopismo naukowe
Tytuł :
NBS1 interacts with Notch signaling in neuronal homeostasis.
Autorzy :
Zhou ZW; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.; School of Medicine (Shenzhen), Sun Yat-Sen University, Guangzhou, China.
Kirtay M; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Schneble N; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Yakoub G; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Ding M; School of Medicine (Shenzhen), Sun Yat-Sen University, Guangzhou, China.
Rüdiger T; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Siniuk K; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Lu R; School of Medicine (Shenzhen), Sun Yat-Sen University, Guangzhou, China.
Jiang YN; School of Medicine (Shenzhen), Sun Yat-Sen University, Guangzhou, China.
Li TL; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.; Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China.
Kaether C; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Barzilai A; Department of Neurobiology, George S. Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Wang ZQ; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.; Faculty of Biological Sciences, Friedrich-Schiller-University Jena, Jena, Germany.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 10924-10939.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*metabolism
Neurons/*metabolism
Receptors, Notch/*metabolism
Acid Anhydride Hydrolases/metabolism ; Animals ; Cells, Cultured ; DNA Damage ; DNA Repair ; Embryo, Mammalian ; Fibroblasts ; MRE11 Homologue Protein/metabolism ; Mice ; Neurons/cytology
Czasopismo naukowe
Tytuł :
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells.
Autorzy :
García-León JA; Departamento Biologia Celular, Genetica y Fisiologia, Facultad de Ciencias, Instituto de Investigacion Biomedica de Malaga-IBIMA, Universidad de Malaga, Malaga, Spain. .; Centro de Investigacion Biomedica en Red Sobre Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain. .; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute, KU Leuven, Leuven, Belgium. .
García-Díaz B; Institut du Cerveau et de la Moelle Epinière-Groupe Hospitalier Pitié-Salpêtrière, INSERM, U1127; CNRS, UMR 7225; Sorbonne Universités, Université Pierre et Marie Curie Paris 06, UM-75, Paris, France.; Unidad de Gestión Clínica de Neurociencias, IBIMA, Hospital Regional Universitario de Málaga, Malaga, Spain.
Eggermont K; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Cáceres-Palomo L; Departamento Biologia Celular, Genetica y Fisiologia, Facultad de Ciencias, Instituto de Investigacion Biomedica de Malaga-IBIMA, Universidad de Malaga, Malaga, Spain.; Centro de Investigacion Biomedica en Red Sobre Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.
Neyrinck K; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Madeiro da Costa R; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Dávila JC; Departamento Biologia Celular, Genetica y Fisiologia, Facultad de Ciencias, Instituto de Investigacion Biomedica de Malaga-IBIMA, Universidad de Malaga, Malaga, Spain.; Centro de Investigacion Biomedica en Red Sobre Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.
Baron-Van Evercooren A; Institut du Cerveau et de la Moelle Epinière-Groupe Hospitalier Pitié-Salpêtrière, INSERM, U1127; CNRS, UMR 7225; Sorbonne Universités, Université Pierre et Marie Curie Paris 06, UM-75, Paris, France.
Gutiérrez A; Departamento Biologia Celular, Genetica y Fisiologia, Facultad de Ciencias, Instituto de Investigacion Biomedica de Malaga-IBIMA, Universidad de Malaga, Malaga, Spain.; Centro de Investigacion Biomedica en Red Sobre Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.
Verfaillie CM; Department of Development and Regeneration, Stem Cell Biology and Embryology, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Pokaż więcej
Źródło :
Nature protocols [Nat Protoc] 2020 Nov; Vol. 15 (11), pp. 3716-3744. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Myelin Sheath/*metabolism
Neural Stem Cells/*cytology
Oligodendroglia/*cytology
Pluripotent Stem Cells/*cytology
Cell Culture Techniques/methods ; Cell Line ; Humans ; Myelin Basic Protein/analysis ; Myelin Basic Protein/metabolism ; Neural Stem Cells/metabolism ; Oligodendroglia/metabolism ; Pluripotent Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles.
Autorzy :
Didiano D; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Abner JJ; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Hinger SA; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Flickinger Z; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Kent M; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Clement MA; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Balaiya S; Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN, 37235, USA.
Liu Q; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37235, USA.
Dai X; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37235, USA.
Levine EM; Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN, 37235, USA.
Patton JG; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA. Electronic address: .
Pokaż więcej
Źródło :
Experimental eye research [Exp Eye Res] 2020 Nov; Vol. 200, pp. 108254. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Extracellular Vesicles*
Neurogenesis*
Photoreceptor Cells, Invertebrate/*metabolism
Proteomics/*methods
Retina/*metabolism
Zebrafish Proteins/*metabolism
Animals ; Animals, Genetically Modified ; Cell Proliferation ; Cells, Cultured ; Injections ; Photoreceptor Cells, Invertebrate/cytology ; Retina/cytology ; Zebrafish
Czasopismo naukowe
Tytuł :
Prenatal Androgenization Alters the Development of GnRH Neuron and Preoptic Area RNA Transcripts in Female Mice.
Autorzy :
Burger LL; Department of Molecular and Integrative Physiology, Ann Arbor, Michigan.
Wagenmaker ER; Department of Molecular and Integrative Physiology, Ann Arbor, Michigan.
Phumsatitpong C; Department of Molecular and Integrative Physiology, Ann Arbor, Michigan.
Olson DP; Department of Molecular and Integrative Physiology, Ann Arbor, Michigan.; Department of Pediatrics, Ann Arbor, Michigan.
Moenter SM; Department of Molecular and Integrative Physiology, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan.
Pokaż więcej
Źródło :
Endocrinology [Endocrinology] 2020 Nov 01; Vol. 161 (11).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Prenatal Exposure Delayed Effects*/chemically induced
Prenatal Exposure Delayed Effects*/genetics
Prenatal Exposure Delayed Effects*/physiopathology
Virilism*/chemically induced
Virilism*/genetics
Virilism*/physiopathology
Neurogenesis/*drug effects
Neurons/*drug effects
Preoptic Area/*drug effects
Androgens/adverse effects ; Animals ; Female ; Gene Expression Regulation, Developmental/drug effects ; Gonadotropin-Releasing Hormone/metabolism ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurogenesis/genetics ; Neurons/metabolism ; Neurons/physiology ; Pregnancy ; Preoptic Area/cytology ; Preoptic Area/growth & development ; Preoptic Area/metabolism ; RNA, Messenger/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sex Factors
Czasopismo naukowe
Tytuł :
Orderly compartmental mapping of premotor inhibition in the developing zebrafish spinal cord.
Autorzy :
Kishore S; Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
Cadoff EB; Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
Agha MA; Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
McLean DL; Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA. .
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2020 Oct 23; Vol. 370 (6515), pp. 431-436.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neurogenesis*
Commissural Interneurons/*physiology
Motor Neurons/*physiology
Spinal Cord/*embryology
Zebrafish/*embryology
Animals ; Axons/physiology ; Locomotion ; Nerve Net/embryology ; Spinal Cord/physiology ; Zebrafish/physiology
Czasopismo naukowe
Tytuł :
Electrical stimulation of the lateral cerebellar nucleus promotes neurogenesis in rats after motor cortical ischemia.
Autorzy :
Wu Z; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Sun F; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Li Z; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Liu M; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Tian X; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Guo D; Department of Experimental Animal Laboratory, Beijing Geriatric Medical Research Center, 45 Changchun Street, Beijing, 100053, China.
Wei P; Department of Neurosurgery, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Shan Y; Department of Neurosurgery, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Liu T; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Guo M; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China.
Zhu Z; Department of Experimental Animal Laboratory, Beijing Geriatric Medical Research Center, 45 Changchun Street, Beijing, 100053, China.
Zheng W; Department of Experimental Animal Laboratory, Beijing Geriatric Medical Research Center, 45 Changchun Street, Beijing, 100053, China.
Wang Y; Department of Experimental Animal Laboratory, Beijing Geriatric Medical Research Center, 45 Changchun Street, Beijing, 100053, China.
Zhao G; Department of Neurosurgery, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China. .
Wang W; Department of Experimental Animal Laboratory, Xuan-Wu Hospital of Capital Medical University, 45 Changchun Street, Beijing, 100053, China. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Oct 06; Vol. 10 (1), pp. 16563. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Recovery of Function*
Brain Ischemia/*physiopathology
Brain Ischemia/*rehabilitation
Cerebellar Nuclei/*physiology
Deep Brain Stimulation/*methods
Electric Stimulation Therapy/*methods
Motor Cortex/*physiopathology
Stroke Rehabilitation/*methods
Animals ; Male ; Rats, Sprague-Dawley
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies