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Tytuł :
Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents.
Autorzy :
Liu Z; Department of Neuroscience, Washington University in St. Louis, St. Louis, MO, USA.
Kimura Y; Department of Neurobiology, National Institute for Basic Biology, Okazaki, Japan.
Higashijima SI; Department of Neurobiology, National Institute for Basic Biology, Okazaki, Japan.
Hildebrand DGC; Laboratory of Neural Systems, The Rockefeller University, New York, NY, USA.
Morgan JL; Department of Ophthalmology, Washington University in St. Louis, St. Louis, MO, USA.
Bagnall MW; Department of Neuroscience, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Nov 25; Vol. 108 (4), pp. 748-762.e4. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons, Afferent/*physiology
Otolithic Membrane/*physiology
Vestibular Nuclei/*physiology
Animals ; Electric Stimulation ; Evoked Potentials, Somatosensory/physiology ; Gene Knock-In Techniques ; Microscopy, Electron ; Neurons/physiology ; Neurons/ultrastructure ; Neurons, Afferent/ultrastructure ; Vestibular Nuclei/ultrastructure ; Zebrafish
Czasopismo naukowe
Tytuł :
Sensory Glia Detect Repulsive Odorants and Drive Olfactory Adaptation.
Autorzy :
Duan D; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China; Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Zhang H; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China.
Yue X; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China.
Fan Y; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China.
Xue Y; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Shao J; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Ding G; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Chen D; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Li S; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Cheng H; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Zhang X; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Zou W; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Liu J; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Zhao J; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Wang L; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Zhao B; Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026, China.
Wang Z; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China.
Xu S; Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Wen Q; Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026, China.
Liu J; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC 3800, Australia.
Duan S; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China; Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China. Electronic address: .
Kang L; Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Nov 25; Vol. 108 (4), pp. 707-721.e8. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroglia/*physiology
Odorants/*analysis
Olfactory Receptor Neurons/*physiology
Receptors, Odorant/*physiology
Smell/*physiology
Animals ; Animals, Genetically Modified ; GABAergic Neurons/physiology ; Mutation ; Neural Inhibition/physiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Operant conditioning of motor cortex neurons reveals neuron-subtype-specific responses in a brain-machine interface task.
Autorzy :
Garcia-Garcia MG; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada. .; The KITE Research Institute, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, M5G 2A2, Canada. .; CRANIA, University Health Network, Toronto, ON, M5T 2S8, Canada. .
Marquez-Chin C; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada.; The KITE Research Institute, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, M5G 2A2, Canada.; CRANIA, University Health Network, Toronto, ON, M5T 2S8, Canada.
Popovic MR; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada.; The KITE Research Institute, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, M5G 2A2, Canada.; CRANIA, University Health Network, Toronto, ON, M5T 2S8, Canada.
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 17; Vol. 10 (1), pp. 19992. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Conditioning, Operant/*physiology
Motor Cortex/*physiology
Motor Neurons/*metabolism
Action Potentials/physiology ; Animals ; Brain-Computer Interfaces ; Male ; Neurons, Efferent/physiology ; Rats ; Rats, Long-Evans ; Reward ; Volition/physiology
Czasopismo naukowe
Tytuł :
Afferent renal innervation in anti-Thy1.1 nephritis in rats.
Autorzy :
Rodionova K; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.
Veelken R; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.; Department of Internal Medicine 4 (Nephrology und Hypertension), Paracelsus Private Medical School, Klinikum Nuremberg, Nuremberg, Germany.
Hilgers KF; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.
Paulus EM; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.
Linz P; Department of Radiology, University of Erlangen, Erlangen, Germany.
Fischer MJM; Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Schenker M; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.; Department of Physiology and Pathophysiology, University Erlangen, Erlangen, Germany.
Reeh P; Department of Physiology and Pathophysiology, University Erlangen, Erlangen, Germany.
Tiegs G; Center of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ott C; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.; Department of Internal Medicine 4 (Nephrology und Hypertension), Paracelsus Private Medical School, Klinikum Nuremberg, Nuremberg, Germany.
Schmieder R; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.
Schiffer M; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.
Amann K; Department of Nephropathology, University of Erlangen, Erlangen, Germany.
Ditting T; Department of Internal Medicine 4 (Nephrology und Hypertension), University of Erlangen, Erlangen, Germany.; Department of Internal Medicine 4 (Nephrology und Hypertension), Paracelsus Private Medical School, Klinikum Nuremberg, Nuremberg, Germany.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Nov 01; Vol. 319 (5), pp. F822-F832. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcitonin Gene-Related Peptide/*pharmacology
Kidney/*drug effects
Nephritis/*drug therapy
Neurons, Afferent/*drug effects
Afferent Pathways/drug effects ; Animals ; Neurons/drug effects ; Rats, Sprague-Dawley ; Substance P/metabolism
Czasopismo naukowe
Tytuł :
Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity.
Autorzy :
Kohro Y; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Matsuda T; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Yoshihara K; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Kohno K; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Koga K; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Katsuragi R; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Oka T; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Tashima R; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Muneta S; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Yamane T; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Okada S; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Momokino K; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Furusho A; Department of Drug Discovery and Evolution, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Hamase K; Department of Drug Discovery and Evolution, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Oti T; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Setouchi, Japan.
Sakamoto H; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Setouchi, Japan.
Hayashida K; Department of Neurophysiology, Graduate School of Medicine, Akita University, Akita, Japan.
Kobayashi R; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.
Horii T; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.
Hatada I; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.
Tozaki-Saitoh H; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Mikoshiba K; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.; Department of Biomolecular Science, Faculty of Science, Toho University, Funabashi, Japan.
Taylor V; Department of Biomedicine, University of Basel, Basel, Switzerland.
Inoue K; Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Tsuda M; Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. .; Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2020 Nov; Vol. 23 (11), pp. 1376-1387. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*physiology
Hyperalgesia/*physiopathology
Locus Coeruleus/*physiology
Neurons/*physiology
Nociception/*physiology
Spinal Cord Dorsal Horn/*physiology
Adrenergic Neurons/physiology ; Animals ; Astrocytes/metabolism ; Basic Helix-Loop-Helix Transcription Factors/analysis ; Female ; Hyperalgesia/chemically induced ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Neural Pathways/physiology ; Receptors, Adrenergic, alpha-1/physiology ; Repressor Proteins/analysis ; Spinal Cord Dorsal Horn/metabolism
Czasopismo naukowe
Tytuł :
Circuit Mechanisms Underlying the Segregation and Integration of Parallel Processing Streams in the Inferior Colliculus.
Autorzy :
Lesicko AMH; Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Sons SK; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Llano DA; Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801 .; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Aug 12; Vol. 40 (33), pp. 6328-6344. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Auditory Pathways/*physiology
GABAergic Neurons/*physiology
Inferior Colliculi/*physiology
Somatosensory Cortex/*physiology
Animals ; Auditory Pathways/cytology ; Female ; Inferior Colliculi/cytology ; Male ; Membrane Potentials ; Mice, Transgenic ; Neural Pathways/physiology ; Neurons/physiology ; Somatosensory Cortex/cytology
Czasopismo naukowe
Tytuł :
Anatomic resolution of neurotransmitter-specific projections to the VTA reveals diversity of GABAergic inputs.
Autorzy :
Soden ME; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Chung AS; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Cuevas B; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Resnick JM; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Awatramani R; Department of Neurology, Northwestern University, Chicago, IL, USA.
Zweifel LS; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. .; Department of Pharmacology, University of Washington, Seattle, WA, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2020 Aug; Vol. 23 (8), pp. 968-980. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
GABAergic Neurons/*metabolism
Synaptic Transmission/*physiology
Ventral Tegmental Area/*metabolism
Animals ; Conditioning, Classical/physiology ; Conditioning, Operant/physiology ; Dopaminergic Neurons/physiology ; Fear/physiology ; Female ; Male ; Mice ; Motor Activity/physiology ; Neural Pathways/metabolism ; Optogenetics ; Reward ; Self Stimulation
Czasopismo naukowe
Tytuł :
How motoneurones control velocity of tension development.
Autorzy :
Baldissera F; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Campadelli P; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Cavallari P; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Piccinelli L; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Tesio L; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
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Źródło :
The Journal of physiology [J Physiol] 2020 Mar; Vol. 598 (5), pp. 1109-1110. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Letter; Comment
MeSH Terms :
Motor Neurons*
Patient Discharge*
Humans ; Neurons, Efferent
Opinia redakcyjna
Tytuł :
Direct translation of findings in isolated animal preparations to in vivo human motoneuron behaviour is challenging.
Autorzy :
Del Vecchio A; Department of Bioengineering, Imperial College London, London, UK.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Negro F; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Holobar A; Faculty of Electrical Engineering and Computer Science, University of Maribor, Slovenia.
Casolo A; Department of Bioengineering, Imperial College London, London, UK.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Folland JP; School of Sport, Exercise & Health Sciences, Loughborough University, Loughborough, UK.
Felici F; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Farina D; Department of Bioengineering, Imperial College London, London, UK.
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Źródło :
The Journal of physiology [J Physiol] 2020 Mar; Vol. 598 (5), pp. 1111-1112. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Letter; Comment
MeSH Terms :
Motor Neurons*
Patient Discharge*
Animals ; Humans ; Muscle Contraction ; Neurons, Efferent
Opinia redakcyjna
Tytuł :
Maternal vitamin A deficiency impairs cholinergic and nitrergic neurons, leading to gastrointestinal dysfunction in rat offspring via RARβ.
Autorzy :
Tan M; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Yang T; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Liu H; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Xiao L; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Li C; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Zhu J; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China.
Chen J; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China. Electronic address: .
Li T; Children's Nutrition Research Center, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Nutrition and Health, China; Ministry of Education Key Laboratory of Child Development and Disorders, China; National Clinical Research Center for Child Health and Disorder, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118688. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinergic Neurons/*metabolism
Gastrointestinal Diseases/*metabolism
Gastrointestinal Tract/*metabolism
Nitrergic Neurons/*metabolism
Receptors, Retinoic Acid/*biosynthesis
Vitamin A Deficiency/*blood
Animals ; Cells, Cultured ; Cholinergic Neurons/pathology ; Female ; Gastrointestinal Diseases/pathology ; Gastrointestinal Tract/pathology ; Nitrergic Neurons/pathology ; Pregnancy ; Prenatal Exposure Delayed Effects ; Rats ; Rats, Sprague-Dawley ; Receptors, Retinoic Acid/antagonists & inhibitors ; Vitamin A Deficiency/complications
Czasopismo naukowe
Tytuł :
Antidotal effects of methylene blue against cyanide neurological toxicity: in vivo and in vitro studies.
Autorzy :
Haouzi P; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
McCann M; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Wang J; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Zhang XQ; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Song J; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Sariyer I; Department of Neurosciences, Temple University School of Medicine, Philadelphia, Pennsylvania.
Langford D; Department of Neurosciences, Temple University School of Medicine, Philadelphia, Pennsylvania.
Santerre M; Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania.
Tubbs N; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Haouzi-Judenherc A; Heart and Vascular Institute, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Cheung JY; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.; Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
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Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2020 Nov; Vol. 1479 (1), pp. 108-121. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neurons*/metabolism
Neurons*/pathology
Neurotoxicity Syndromes*/metabolism
Neurotoxicity Syndromes*/pathology
Neurotoxicity Syndromes*/prevention & control
Antidotes/*pharmacology
Methylene Blue/*pharmacology
Potassium Cyanide/*toxicity
Animals ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Humans ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
PNOC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding.
Autorzy :
Jais A; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Paeger L; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Sotelo-Hitschfeld T; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Bremser S; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Prinzensteiner M; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Klemm P; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Mykytiuk V; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Widdershooven PJM; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Vesting AJ; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Grzelka K; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Minère M; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Cremer AL; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Xu J; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Korotkova T; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Lowell BB; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02215, USA.
Zeilhofer HU; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zurich, Switzerland; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland.
Backes H; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Fenselau H; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Wunderlich FT; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Kloppenburg P; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany. Electronic address: .
Brüning JC; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jun 17; Vol. 106 (6), pp. 1009-1025.e10. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet, High-Fat*
Hyperphagia*
Obesity*
Arcuate Nucleus of Hypothalamus/*physiology
Feeding Behavior/*physiology
GABAergic Neurons/*physiology
Weight Gain/*physiology
Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/metabolism ; GABAergic Neurons/metabolism ; Mice ; Neural Inhibition/physiology ; Neurons/metabolism ; Neurons/physiology ; Optogenetics ; Pro-Opiomelanocortin/metabolism ; Protein Precursors/metabolism ; Receptors, Opioid/metabolism ; Septal Nuclei/physiology
Czasopismo naukowe
Tytuł :
Developmental decrease in parvalbumin-positive neurons precedes increase in flurothyl-induced seizure susceptibility in the Brd2 mouse model of juvenile myoclonic epilepsy.
Autorzy :
McCarthy E; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
Shakil F; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
Saint Ange P; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
Morris Cameron E; Department of Pediatrics, Wexner Medical Center, Ohio State University and Battelle Center for Mathematical Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Miller J; Department of Pediatrics, Wexner Medical Center, Ohio State University and Battelle Center for Mathematical Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Pathak S; Department of Pediatrics, Wexner Medical Center, Ohio State University and Battelle Center for Mathematical Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Greenberg DA; Department of Pediatrics, Wexner Medical Center, Ohio State University and Battelle Center for Mathematical Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Velíšková J; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.; Department of Obstetrics & Gynecology, New York Medical College, Valhalla, New York.; Department of Neurology, New York Medical College, Valhalla, New York.
Velíšek L; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.; Department of Neurology, New York Medical College, Valhalla, New York.; Department of Pediatrics, New York Medical College, Valhalla, New York.
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Źródło :
Epilepsia [Epilepsia] 2020 May; Vol. 61 (5), pp. 892-902. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Flurothyl/*pharmacology
Myoclonic Epilepsy, Juvenile/*pathology
Neurons/*pathology
Parvalbumins/*metabolism
Seizures/*chemically induced
Androstenedione/analogs & derivatives ; Androstenedione/pharmacology ; Animals ; Disease Models, Animal ; Female ; GABAergic Neurons/drug effects ; GABAergic Neurons/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Myoclonic Epilepsy, Juvenile/chemically induced ; Neurons/drug effects ; Seizures/pathology ; Testosterone Propionate/pharmacology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis.
Autorzy :
Zhu X; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Yao Y; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China; Department of Anesthesiology, Hunan Children's Hospital, Changsha, 410007, China.
Guo M; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Li J; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Yang P; Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Xu H; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China. Electronic address: .
Lin D; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Jan 01; Vol. 336, pp. 11-20. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Anesthetics, Inhalation/*toxicity
Apoptosis/*drug effects
Calcium/*metabolism
Calcium Signaling/*drug effects
Hippocampus/*drug effects
Mitochondria/*drug effects
Neurons/*drug effects
Sevoflurane/*toxicity
Animals ; Animals, Newborn ; Apoptosis Regulatory Proteins/metabolism ; Calcium Channels, L-Type/drug effects ; Calcium Channels, L-Type/metabolism ; Cells, Cultured ; Hippocampus/metabolism ; Hippocampus/pathology ; Mitochondria/metabolism ; Mitochondria/pathology ; Neurons/metabolism ; Neurons/pathology ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
The pivotal role of ubiquitin-activating enzyme E1 (UBA1) in neuronal health and neurodegeneration.
Autorzy :
Lambert-Smith IA; Illawarra Health and Medical Research Institute, Northfields Avenue, Wollongong, NSW 2522, Australia; School of Chemistry and Molecular Bioscience, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia.
Saunders DN; School of Medical Sciences, UNSW, Sydney, Australia. Electronic address: .
Yerbury JJ; Illawarra Health and Medical Research Institute, Northfields Avenue, Wollongong, NSW 2522, Australia; School of Chemistry and Molecular Bioscience, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia. Electronic address: .
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Źródło :
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2020 Jun; Vol. 123, pp. 105746. Date of Electronic Publication: 2020 Apr 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Ubiquitination*/genetics
Neurodegenerative Diseases/*enzymology
Neurons/*enzymology
Ubiquitin-Activating Enzymes/*metabolism
Animals ; Autophagy/genetics ; Humans ; Motor Neurons/metabolism ; Muscular Atrophy, Spinal/genetics ; Muscular Atrophy, Spinal/metabolism ; Muscular Atrophy, Spinal/physiopathology ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/physiopathology ; Neurodegenerative Diseases/therapy ; Neurons/metabolism ; Signal Transduction/genetics ; Ubiquitin/metabolism ; Ubiquitin-Activating Enzymes/chemistry ; Ubiquitin-Activating Enzymes/genetics ; Ubiquitin-Activating Enzymes/physiology
Czasopismo naukowe
Tytuł :
Periaqueductal Gray and Rostromedial Tegmental Inhibitory Afferents to VTA Have Distinct Synaptic Plasticity and Opiate Sensitivity.
Autorzy :
St Laurent R; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA.
Martinez Damonte V; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA.
Tsuda AC; Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA.
Kauer JA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 May 20; Vol. 106 (4), pp. 624-636.e4. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Analgesics, Opioid/*pharmacology
Neuronal Plasticity/*physiology
Neurons, Afferent/*physiology
Periaqueductal Gray/*physiology
Ventral Tegmental Area/*physiology
Animals ; Female ; GABAergic Neurons/drug effects ; GABAergic Neurons/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Morphine/pharmacology ; Neuronal Plasticity/drug effects ; Neurons, Afferent/drug effects ; Periaqueductal Gray/drug effects ; Tegmentum Mesencephali ; Ventral Tegmental Area/drug effects
Czasopismo naukowe
Tytuł :
The neuroprotective effect of osthole against chronic sleep deprivation (CSD)-induced memory impairment in rats.
Autorzy :
Tang H; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China. Electronic address: .
Li K; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China.
Dou X; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China.
Zhao Y; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China.
Huang C; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China.
Shu F; School of Basic Medicine, Youjiang Medical University for Nationalities, No. 98, Chengxiang Road, Youjiang District, Baise City, Guangxi Province 533000, China.
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118524. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Behavior, Animal/*drug effects
Calcium Channel Blockers/*pharmacology
Coumarins/*pharmacology
Memory Disorders/*drug therapy
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Sleep Deprivation/*complications
Animals ; Disease Models, Animal ; Male ; Memory Disorders/etiology ; Memory Disorders/metabolism ; Memory Disorders/pathology ; Neurons/metabolism ; Neurons/pathology ; Oxidative Stress ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Reactive oxygen species regulate miR-17-5p expression via DNA methylation in paraquat-induced nerve cell damage.
Autorzy :
Zhan Y; Department of Health Management, Fujian Health College, Fuzhou, China.; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Guo Z; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.; Key Laboratory of Environment and Health, Universities and Colleges in Fujian, School of Public Health, Fujian Medical University, Fuzhou, China.
Zheng F; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.; Key Laboratory of Environment and Health, Universities and Colleges in Fujian, School of Public Health, Fujian Medical University, Fuzhou, China.
Zhang Z; Fujian Provincial Center for Adverse Drug Reaction Monitoring, Fujian Provincial Food and Drug Administration, Fuzhou, China.
Li K; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Wang Q; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Wang L; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Cai Z; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Chen N; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Wu S; Key Laboratory of Environment and Health, Universities and Colleges in Fujian, School of Public Health, Fujian Medical University, Fuzhou, China.; Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environmental Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Li H; Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.; Key Laboratory of Environment and Health, Universities and Colleges in Fujian, School of Public Health, Fujian Medical University, Fuzhou, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2020 Dec; Vol. 35 (12), pp. 1364-1373. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation/*drug effects
MicroRNAs/*genetics
Neurons/*drug effects
Oxidative Stress/*drug effects
Paraquat/*toxicity
Reactive Oxygen Species/*metabolism
Acetylcysteine/pharmacology ; Animals ; Antioxidants/pharmacology ; Cell Culture Techniques ; Cell Line, Tumor ; DNA Methylation/genetics ; Decitabine/pharmacology ; Dose-Response Relationship, Drug ; Down-Regulation ; Mice ; Neurons/metabolism ; Neurons/pathology ; Oxidative Stress/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Glial cells in Parkinson´s disease: protective or deleterious?
Autorzy :
Domingues AV; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal.
Pereira IM; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal.
Vilaça-Faria H; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal.
Salgado AJ; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal.
Rodrigues AJ; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal. .; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal. .
Teixeira FG; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal. .; ICVS/3B's Associate Lab, PT Government Associated Laboratory, Braga/Guimarães, Portugal. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (24), pp. 5171-5188. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell- and Tissue-Based Therapy*
Neuroglia/*transplantation
Neurons/*transplantation
Parkinson Disease/*therapy
Central Nervous System/pathology ; Humans ; Nerve Degeneration/pathology ; Nerve Degeneration/therapy ; Neurons/pathology ; Parkinson Disease/pathology
Czasopismo naukowe
Tytuł :
Low-Level Inhibition of GABAergic Synapses Enhances Gene Expressions Crucial for Neuronal Plasticity in the Hippocampus After Ischemic Stroke.
Autorzy :
Okamura M; Graduate School of Health Sciences, Hokkaido University, Kita 12 Nishi 5, Kita-ku, Sapporo 060-0812, Japan. Electronic address: .
Inoue T; Graduate School of Health Sciences, Hokkaido University, Kita 12 Nishi 5, Kita-ku, Sapporo 060-0812, Japan; Research Fellow of Japan Society for the Promotion of Science, 5-3-1 Kojimachi, Chiyoda-ku, Tokyo 102-0083, Japan. Electronic address: .
Takamatsu Y; Department of Rehabilitation Science, Faculty of Health Sciences, Hokkaido University, Kita 12 Nishi 5, Kita-ku, Sapporo 060-0812, Japan. Electronic address: .
Maejima H; Department of Rehabilitation Science, Faculty of Health Sciences, Hokkaido University, Kita 12 Nishi 5, Kita-ku, Sapporo 060-0812, Japan. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Dec; Vol. 29 (12), pp. 105316. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Bicuculline/*pharmacology
GABA-A Receptor Antagonists/*pharmacology
GABAergic Neurons/*drug effects
Hippocampus/*drug effects
Infarction, Middle Cerebral Artery/*drug therapy
Infarction, Middle Cerebral Artery/*genetics
Neural Inhibition/*drug effects
Neuronal Plasticity/*drug effects
Synaptic Transmission/*drug effects
Animals ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; Disease Models, Animal ; Disks Large Homolog 4 Protein/genetics ; Disks Large Homolog 4 Protein/metabolism ; GABAergic Neurons/metabolism ; GABAergic Neurons/pathology ; Gene Expression Regulation ; Hippocampus/metabolism ; Hippocampus/pathology ; Hippocampus/physiopathology ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/physiopathology ; Male ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Rats, Sprague-Dawley ; Receptor, trkB/genetics ; Receptor, trkB/metabolism ; Receptors, Growth Factor/genetics ; Receptors, Growth Factor/metabolism ; Synaptophysin/genetics ; Synaptophysin/metabolism
Czasopismo naukowe

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