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Tytuł:
Enhanced Release Probability without Changes in Synaptic Delay during Analogue-Digital Facilitation.
Autorzy:
Boudkkazi S; Physiology Institute, University of Freiburg, 79104 Freiburg, Germany.; Unité de Neurobiologie des Canaux Ioniques et de la Synapse (UNIS), Institut National de la Santé et de la Recherche Médicale (INSERM), Aix-Marseille University, 13015 Marseille, France.
Debanne D; Unité de Neurobiologie des Canaux Ioniques et de la Synapse (UNIS), Institut National de la Santé et de la Recherche Médicale (INSERM), Aix-Marseille University, 13015 Marseille, France.
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Źródło:
Cells [Cells] 2024 Mar 26; Vol. 13 (7). Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
Synapses*/physiology
Neurons*
Action Potentials/physiology ; Pyramidal Cells/physiology ; Long-Term Potentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fluorescent Molecules That Help Reveal Previously Unidentified Neural Connections in Adult, Neonatal and Peripubertal Mammals.
Autorzy:
Vasziné Szabó E; Department of Restorative Dentistry and Endodontics, Faculty of Dentistry, Semmelweis University, Szentkirályi u. 47, H-1088 Budapest, Hungary.
Köves K; Department of Anatomy, Histology and Embryology, Faculty of Medicine, Semmelweis University, Tűzoltó u. 58, H-1094 Budapest, Hungary.
Csáki Á; Department of Anatomy, Histology and Embryology, Faculty of Medicine, Semmelweis University, Tűzoltó u. 58, H-1094 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 23; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurons*/pathology
Synapses*/physiology
Animals ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Time-dependent homeostatic mechanisms underlie brain-derived neurotrophic factor action on neural circuitry.
Autorzy:
O'Neill KM; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Biomedical Engineering Graduate Program, Rutgers University, Piscataway, NJ, USA.; Institute for Physical Science & Technology, University of Maryland, College Park, MD, USA.
Anderson ED; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Mukherjee S; Department of Electrical and Computer Engineering, University of Maryland, College Park, MD, USA.
Gandu S; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Cell and Developmental Biology Graduate Program, Rutgers University, Piscataway, NJ, USA.
McEwan SA; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Neuroscience Graduate Program, Rutgers University, Piscataway, NJ, USA.
Omelchenko A; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Neuroscience Graduate Program, Rutgers University, Piscataway, NJ, USA.
Rodriguez AR; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Biomedical Engineering Graduate Program, Rutgers University, Piscataway, NJ, USA.
Losert W; Department of Physics, University of Maryland, College Park, MD, USA.; Institute for Physical Science & Technology, University of Maryland, College Park, MD, USA.
Meaney DF; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Babadi B; Department of Electrical and Computer Engineering, University of Maryland, College Park, MD, USA.
Firestein BL; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Dec 18; Vol. 6 (1), pp. 1278. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Brain-Derived Neurotrophic Factor*/pharmacology
Brain-Derived Neurotrophic Factor*/metabolism
Synapses*/metabolism
Cells, Cultured ; Neurons/physiology ; Glutamic Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An abundance of free regulatory (19 S ) proteasome particles regulates neuronal synapses.
Autorzy:
Sun C; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
Desch K; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
Nassim-Assir B; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
Giandomenico SL; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
Nemcova P; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
Langer JD; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.; Max Planck Institute for Biophysics, 60438 Frankfurt am Main, Germany.
Schuman EM; Max Planck Institute for Brain Research, 60438 Frankfurt am Main, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2023 May 26; Vol. 380 (6647), pp. eadf2018. Date of Electronic Publication: 2023 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
Neurons*/metabolism
Proteasome Endopeptidase Complex*/metabolism
Synapses*/metabolism
Animals ; Rats ; Proteolysis ; Ubiquitin/metabolism ; Lysine/metabolism ; Synaptic Transmission
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Improved Method for Growing Primary Neurons on Electron Microscopy Grids Co-Cultured with Astrocytes.
Autorzy:
Kumar I; Diamond Light Source, Harwell Science and Innovation Campus, Fermi Ave, Didcot OX11 0DE, UK.
Paudyal A; Mary Lyon Centre at MRC Harwell, Harwell Campus, Becquerel Ave, Didcot OX11 ORD, UK.
Kádková A; Department of Neuroscience, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Stewart M; Mary Lyon Centre at MRC Harwell, Harwell Campus, Becquerel Ave, Didcot OX11 ORD, UK.
Sørensen JB; Department of Neuroscience, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Radecke J; Diamond Light Source, Harwell Science and Innovation Campus, Fermi Ave, Didcot OX11 0DE, UK.; Department of Neuroscience, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 14; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*
Synapses*
Cryoelectron Microscopy/methods ; Electron Microscope Tomography/methods ; Neurons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Simple and Highly Efficient Detection of PSD95 Using a Nanobody and Its Recombinant Heavy-Chain Antibody Derivatives.
Autorzy:
Kilisch M; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Gere-Becker M; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Wüstefeld L; Synaptic Systems GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Bonnas C; Synaptic Systems GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Crauel A; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Mechmershausen M; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Martens H; Synaptic Systems GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Götzke H; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
Opazo F; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.; Institute of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.; Center for Biostructural Imaging of Neurodegeneration (BIN), University of Göttingen Medical Center, 37075 Göttingen, Germany.
Frey S; NanoTag Biotechnologies GmbH, Rudolf-Wissell-Straβe 28a, 37079 Göttingen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 14; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 14.
Typ publikacji:
Journal Article
MeSH Terms:
Synapses*/metabolism
Neurons*/metabolism
Rats ; Mice ; Humans ; Animals ; Disks Large Homolog 4 Protein/metabolism ; Post-Synaptic Density/metabolism ; Ion Channels/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploiting the molecular diversity of the synapse to investigate neuronal communication: A guide through the current toolkit.
Autorzy:
Lamanna J; Center for Behavioral Neuroscience and Communication (BNC), Vita-Salute San Raffaele University, Milan, Italy.; Faculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy.
Ferro M; Center for Behavioral Neuroscience and Communication (BNC), Vita-Salute San Raffaele University, Milan, Italy.; Department of Psychology, Sigmund Freud University, Milan, Italy.
Spadini S; Center for Behavioral Neuroscience and Communication (BNC), Vita-Salute San Raffaele University, Milan, Italy.; Faculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy.
Malgaroli A; Center for Behavioral Neuroscience and Communication (BNC), Vita-Salute San Raffaele University, Milan, Italy.; Faculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy.; San Raffaele Turro, IRCCS Ospedale San Raffaele, Milan, Italy.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 Dec; Vol. 56 (12), pp. 6141-6161. Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Synapses*/physiology
Neurons*/physiology
Synaptic Transmission/physiology ; Optogenetics/methods ; Brain/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proteasome cap particle regulates synapses.
Autorzy:
Türker F; Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Margolis SS; Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 May 26; Vol. 380 (6647), pp. 795-796. Date of Electronic Publication: 2023 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*
Synapses*
Neurons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Formulation and Emulation of Quantum-Inspired Dynamical Systems With Classical Analog Circuits.
Autorzy:
Cressman AJ; Department of Physics, Dartmouth College, Hanover, NH 03755, U.S.A. .
Wattanapanitch W; Department of Electrical Engineering, Kasetsart University, Bangkok 10900, Thailand .
Chuang I; Departments of Electrical Engineering and Physics, MIT, Cambridge, MA 02139, U.S.A. .
Sarpeshkar R; Departments of Engineering, Physics, Microbiology and Immunology, and Molecular and Systems Biology, Dartmouth College, Hanover, NH 03755, U.S.A. .
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Źródło:
Neural computation [Neural Comput] 2022 Mar 23; Vol. 34 (4), pp. 856-890.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Neurons*/physiology
Synapses*/physiology
Computer Simulation ; Computers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activity dependent dissociation of the Homer1 interactome.
Autorzy:
Stillman M; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Dartmouth-Hitchcock Medical Center Psychiatry Residency Program, Dartmouth, NH, USA.
Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Johnson RS; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA. .; Department of Pediatrics, University of Washington, Seattle, WA, USA. .; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 25; Vol. 12 (1), pp. 3207. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurons*/metabolism
Synapses*/metabolism
Animals ; Cerebral Cortex/metabolism ; Homer Scaffolding Proteins/genetics ; Homer Scaffolding Proteins/metabolism ; Mice ; Mice, Knockout ; Microfilament Proteins/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acute Ethanol Exposure during Synaptogenesis Rapidly Alters Medium Spiny Neuron Morphology and Synaptic Protein Expression in the Dorsal Striatum.
Autorzy:
Clabough E; Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA.
Ingersoll J; Department of Biology, Hampden-Sydney College, Hampden-Sydney, VA 23943, USA.
Reekes T; Department of Biology, Hampden-Sydney College, Hampden-Sydney, VA 23943, USA.; Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA 71104, USA.
Gleichsner A; Department of Biological Science, SUNY Plattsburgh, Plattsburgh, NY 12901, USA.
Ryan A; Department of Biological Science, SUNY Plattsburgh, Plattsburgh, NY 12901, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 28; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Neurogenesis*/drug effects
Corpus Striatum/*pathology
Ethanol/*toxicity
Nerve Tissue Proteins/*metabolism
Neurons/*pathology
Synapses/*metabolism
Animals ; Dendritic Spines/drug effects ; Dendritic Spines/metabolism ; Ethanol/administration & dosage ; Female ; Golgi Apparatus/drug effects ; Golgi Apparatus/metabolism ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism ; Synapses/drug effects ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Digging Deeper: Advancements in Visualization of Inhibitory Synapses in Neurodegenerative Disorders.
Autorzy:
Radulović S; Gottfried Schatz Research Center, Division of Cell Biology, Histology and Embryology, Medical University of Graz, 8010 Graz, Austria.
Sunkara S; Gottfried Schatz Research Center, Division of Cell Biology, Histology and Embryology, Medical University of Graz, 8010 Graz, Austria.
Maurer C; Gottfried Schatz Research Center, Division of Macroscopic and Clinical Anatomy, Medical University of Graz, 8010 Graz, Austria.
Leitinger G; Gottfried Schatz Research Center, Division of Cell Biology, Histology and Embryology, Medical University of Graz, 8010 Graz, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 18; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease/*diagnostic imaging
Brain/*diagnostic imaging
Neurons/*ultrastructure
Neuroprotective Agents/*therapeutic use
Parkinson Disease/*diagnostic imaging
Synapses/*ultrastructure
Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyotrophic Lateral Sclerosis/diagnostic imaging ; Amyotrophic Lateral Sclerosis/drug therapy ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Humans ; Huntington Disease/diagnostic imaging ; Huntington Disease/drug therapy ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Levodopa/therapeutic use ; Memantine/therapeutic use ; Microscopy, Electron/methods ; Multiple Sclerosis/diagnostic imaging ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/metabolism ; Multiple Sclerosis/pathology ; Neuronal Plasticity/drug effects ; Neurons/drug effects ; Neurons/metabolism ; Neurotransmitter Agents/metabolism ; Parkinson Disease/drug therapy ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Synapses/drug effects ; Synapses/metabolism ; Synaptic Transmission/drug effects ; Tetrabenazine/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer's patients and high-pathology controls.
Autorzy:
Jiang H; Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America.
Esparza TJ; Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America.; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America.; National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, United States of America.
Kummer TT; Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America.
Brody DL; Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America.; National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, United States of America.; Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Nov 08; Vol. 16 (11), pp. e0259335. Date of Electronic Publication: 2021 Nov 08 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Alzheimer Disease/*pathology
Brain/*pathology
Neurons/*pathology
Synapses/*pathology
Aged ; Aged, 80 and over ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Brain/metabolism ; Case-Control Studies ; Female ; High-Throughput Screening Assays ; Humans ; Male ; Mice ; Neurons/metabolism ; Primary Cell Culture ; Synapses/metabolism ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Balancing neuronal circuits.
Autorzy:
Blumenstock S; Molecular Neurodegeneration Group, Max Planck Institute for Biological Intelligence, i.f., Martinsried, Germany.; Department of Molecules-Signaling-Development, Max Planck Institute for Biological Intelligence, i.f., Martinsried, Germany.; Department of Neurobiology, Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San Diego, CA, USA.
Dudanova I; Molecular Neurodegeneration Group, Max Planck Institute for Biological Intelligence, i.f., Martinsried, Germany.; Department of Molecules-Signaling-Development, Max Planck Institute for Biological Intelligence, i.f., Martinsried, Germany.; Center for Anatomy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Sep 23; Vol. 377 (6613), pp. 1383-1384. Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Dioxoles*/pharmacology
Dioxoles*/therapeutic use
Huntington Disease*/embryology
Huntington Disease*/genetics
Huntington Disease*/prevention & control
Nerve Net*/abnormalities
Nerve Net*/pathology
Piperidines*/pharmacology
Piperidines*/therapeutic use
Synapses*/drug effects
Synapses*/pathology
Aging ; Animals ; Mice ; Mice, Transgenic ; Neurons/drug effects ; Neurons/pathology ; Neurons/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins.
Autorzy:
Liu X; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Hua F; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Yang D; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Lin Y; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Zhang L; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Ying J; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Sheng H; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. .
Wang X; Key Laboratory of Anesthesiology of Jiangxi Province, 1# Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China. .; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Sep 10; Vol. 20 (1), pp. 418. Date of Electronic Publication: 2022 Sep 10.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroglia*
Synapses*/metabolism
Brain ; Neurogenesis ; Neurons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NMDAR-dependent somatic potentiation of synaptic inputs is correlated with β amyloid-mediated neuronal hyperactivity.
Autorzy:
Bao Y; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Yang X; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Fu Y; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Li Z; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Gong R; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Lu W; MOE Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing, 210096, China. .; Department of Neurology, Huashan Hospital, Institute for Translational Brain Research, State Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, Fudan University, Shanghai, 200032, China. .; Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China. .
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Źródło:
Translational neurodegeneration [Transl Neurodegener] 2021 Sep 08; Vol. 10 (1), pp. 34. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyloid beta-Peptides/*toxicity
Cell Body/*physiology
Excitatory Postsynaptic Potentials/*physiology
Neurons/*physiology
Peptide Fragments/*toxicity
Receptors, N-Methyl-D-Aspartate/*physiology
Synapses/*physiology
Animals ; Aspartic Acid/toxicity ; Cell Body/drug effects ; Excitatory Postsynaptic Potentials/drug effects ; Humans ; Male ; Neurons/drug effects ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley ; Synapses/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons.
Autorzy:
Racine AS; Centre for Interdisciplinary Research on Brain and Learning, Research Group on the Central Nervous System, Department of Neurosciences, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, QC, H3C 3J7, Canada.
Michon FX; Centre for Interdisciplinary Research on Brain and Learning, Research Group on the Central Nervous System, Department of Neurosciences, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, QC, H3C 3J7, Canada.
Laplante I; Centre for Interdisciplinary Research on Brain and Learning, Research Group on the Central Nervous System, Department of Neurosciences, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, QC, H3C 3J7, Canada.
Lacaille JC; Centre for Interdisciplinary Research on Brain and Learning, Research Group on the Central Nervous System, Department of Neurosciences, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, QC, H3C 3J7, Canada. .
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Źródło:
Molecular brain [Mol Brain] 2021 Aug 24; Vol. 14 (1), pp. 130. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CA1 Region, Hippocampal/*drug effects
Excitatory Postsynaptic Potentials/*drug effects
GABAergic Neurons/*drug effects
Interneurons/*drug effects
Long-Term Potentiation/*drug effects
Somatostatin/*physiology
Synapses/*drug effects
Animals ; Bacterial Proteins ; Cysteamine/pharmacology ; Female ; GABA-A Receptor Antagonists/pharmacology ; GABAergic Neurons/metabolism ; Gene Knock-In Techniques ; Genes, Reporter ; Humans ; Interneurons/metabolism ; Luminescent Proteins ; Male ; Memory/physiology ; Mice ; Mice, Transgenic ; Peptides, Cyclic/pharmacology ; Receptors, Metabotropic Glutamate/physiology ; Receptors, N-Methyl-D-Aspartate/physiology ; Receptors, Somatostatin/drug effects ; Receptors, Somatostatin/physiology ; Somatostatin/pharmacology ; Synapses/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reelin Affects Signaling Pathways of a Group of Inhibitory Neurons and the Development of Inhibitory Synapses in Primary Neurons.
Autorzy:
Lee SE; College of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 61452, Korea.
Lee GH; College of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 61452, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 13; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Inhibitory Postsynaptic Potentials*
Neural Inhibition*
Neuronal Plasticity*
Cell Adhesion Molecules, Neuronal/*metabolism
Dendrites/*physiology
Extracellular Matrix Proteins/*metabolism
Nerve Tissue Proteins/*metabolism
Neurons/*physiology
Serine Endopeptidases/*metabolism
Synapses/*physiology
Animals ; Cell Adhesion Molecules, Neuronal/genetics ; Extracellular Matrix Proteins/genetics ; Hippocampus/cytology ; Hippocampus/physiology ; Mice ; Mice, Inbred ICR ; Nerve Tissue Proteins/genetics ; Neurogenesis ; Neurons/cytology ; Reelin Protein ; Serine Endopeptidases/genetics ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
In vitro zinc supplementation alters synaptic deficits caused by autism spectrum disorder-associated Shank2 point mutations in hippocampal neurons.
Autorzy:
Vyas Y; Department of Physiology and Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Jung Y; Department of Physiology and Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Lee K; Department of Physiology and Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Garner CC; German Center for Neurodegenerative Diseases, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Montgomery JM; Department of Physiology and Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand. .
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Źródło:
Molecular brain [Mol Brain] 2021 Jun 24; Vol. 14 (1), pp. 95. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dietary Supplements*
Autism Spectrum Disorder/*genetics
Hippocampus/*pathology
Nerve Tissue Proteins/*genetics
Neurons/*pathology
Point Mutation/*genetics
Synapses/*pathology
Zinc/*pharmacology
Animals ; Animals, Newborn ; Autism Spectrum Disorder/pathology ; Female ; Glutamic Acid/metabolism ; Male ; Neurons/drug effects ; Neurons/metabolism ; Rats ; Synapses/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1356

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