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Tytuł :
Taraxasterol protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activation of Nrf2 signalling pathway.
Autorzy :
He Y; Department of Neurology, AnKang Central Hospital, AnKang, China.
Jiang K; Department of Neurology, AnKang Central Hospital, AnKang, China.
Zhao X; Department of Neurology, AnKang Central Hospital, AnKang, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 252-258.
Typ publikacji :
Journal Article
MeSH Terms :
Glucose/*deficiency
Hippocampus/*cytology
NF-E2-Related Factor 2/*metabolism
Neurons/*drug effects
Oxygen/*metabolism
Signal Transduction/*drug effects
Sterols/*pharmacology
Triterpenes/*pharmacology
Animals ; Apoptosis/drug effects ; Cytoprotection/drug effects ; Female ; Mice ; Neurons/cytology ; Neurons/metabolism ; Oxidative Stress/drug effects ; Pregnancy
Czasopismo naukowe
Tytuł :
Insulin-Like Growth Factor 2 (IGF-2) Regulates Neuronal Density and IGF-2 Distribution Following Hippocampal Intracerebral Hemorrhage.
Autorzy :
Vafaee F; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Zarifkar A; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Emamghoreishi M; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Pharmacology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Namavar MR; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Histomorphometry and Stereology Research center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Shirzad S; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghazavi H; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: .
Mahdavizadeh V; Student Research committee, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105128. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Hemorrhage/*drug therapy
Hippocampus/*drug effects
Insulin-Like Growth Factor II/*administration & dosage
Neurons/*drug effects
Neuroprotective Agents/*administration & dosage
Animals ; Cell Death/drug effects ; Cerebral Hemorrhage/metabolism ; Cerebral Hemorrhage/pathology ; Hippocampus/metabolism ; Hippocampus/pathology ; Insulin-Like Growth Factor II/metabolism ; Male ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/metabolism ; Rats, Sprague-Dawley ; Recombinant Proteins/administration & dosage ; Time Factors ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Endonuclease VIII-like 1 deficiency impairs survival of newly generated hippocampal neurons and memory performance in young-adult male mice.
Autorzy :
Kuo YY; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institue of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lin YC; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Calkins MJ; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan. Electronic address: .
Chen PC; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institue of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Aug 01; Vol. 254, pp. 117755. Date of Electronic Publication: 2020 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cognition/*physiology
DNA Glycosylases/*deficiency
Hippocampus/*enzymology
Memory/*physiology
Neurons/*enzymology
Animals ; Cell Differentiation/physiology ; Cell Survival/physiology ; Cognitive Dysfunction/enzymology ; Cognitive Dysfunction/pathology ; DNA Glycosylases/genetics ; DNA Glycosylases/metabolism ; Dentate Gyrus/cytology ; Dentate Gyrus/enzymology ; Hippocampus/cytology ; Hippocampus/metabolism ; Learning/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neurogenesis/physiology ; Neurons/cytology
Czasopismo naukowe
Tytuł :
VAMP4 Maintains a Ca -Sensitive Pool of Spontaneously Recycling Synaptic Vesicles.
Autorzy :
Lin PY; Department of Pharmacology, Vanderbilt University, Nashville, TN 37240-7933.; Department of Neuroscience, the University of Texas Southwestern Medical Center, Dallas, TX 75390-9111.
Chanaday NL; Department of Pharmacology, Vanderbilt University, Nashville, TN 37240-7933.
Horvath PM; Department of Pharmacology, Vanderbilt University, Nashville, TN 37240-7933.; Department of Neuroscience, the University of Texas Southwestern Medical Center, Dallas, TX 75390-9111.
Ramirez DMO; Department of Neurology and Neurotherapeutics, the University of Texas Southwestern Medical Center, Dallas, TX 75390-8813.
Monteggia LM; Department of Pharmacology, Vanderbilt University, Nashville, TN 37240-7933.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232-2050.
Kavalali ET; Department of Pharmacology, Vanderbilt University, Nashville, TN 37240-7933 .; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232-2050.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jul 08; Vol. 40 (28), pp. 5389-5401. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Hippocampus/*metabolism
Neurons/*metabolism
R-SNARE Proteins/*metabolism
Synaptic Vesicles/*metabolism
Action Potentials/physiology ; Animals ; Cells, Cultured ; Female ; Hippocampus/cytology ; Male ; Mice ; Neurons/cytology ; Patch-Clamp Techniques ; R-SNARE Proteins/genetics ; Rats ; Rats, Sprague-Dawley ; Synapses/metabolism ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł :
PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function.
Autorzy :
Wang Y; Department of Neuroscience, Genentech Inc., South San Francisco, CA, 94080, USA. .
Kerrisk Campbell M; Department of Neuroscience, Genentech Inc., South San Francisco, CA, 94080, USA.; Alkahest Inc., San Carlos, CA, 94070, USA.
Tom I; Department of OMNI-Biomarker, Genentech Inc., South San Francisco, CA, 94080, USA.
Foreman O; Department of Pathology, Genentech Inc., South San Francisco, CA, 94080, USA.
Hanson JE; Department of Neuroscience, Genentech Inc., South San Francisco, CA, 94080, USA.
Sheng M; Department of Neuroscience, Genentech Inc., South San Francisco, CA, 94080, USA. .; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 02; Vol. 10 (1), pp. 10951. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Synaptic Transmission*
Cadherins/*metabolism
Dendritic Spines/*physiology
Hippocampus/*cytology
Neurons/*physiology
Receptors, N-Methyl-D-Aspartate/*metabolism
Animals ; Cadherins/genetics ; Female ; Hippocampus/physiology ; Neurons/cytology ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Microglia modulate the structure and function of the hippocampus after early-life seizures.
Autorzy :
Andoh M; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Ikegaya Y; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Koyama R; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Dec; Vol. 144 (4), pp. 212-217. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Communication*
Epilepsy, Temporal Lobe/*etiology
Epilepsy, Temporal Lobe/*pathology
Hippocampus/*cytology
Hippocampus/*pathology
Microglia/*pathology
Microglia/*physiology
Age Factors ; Age of Onset ; Animals ; Dentate Gyrus/cytology ; Dentate Gyrus/pathology ; Disease Models, Animal ; Humans ; Mice ; Neurons/physiology ; Rats ; Risk Factors ; Seizures, Febrile/etiology ; Seizures, Febrile/pathology ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta 1-42 infused rat model.
Autorzy :
Elibol B; Department of Medical Biology, Faculty of Medicine, Bezmialem Vakif University, 34093 Istanbul, Turkey. Electronic address: .
Beker M; Department of Medical Biology, Faculty of Medicine, University of Health Sciences Turkey, 34668 Istanbul, Turkey.
Terzioglu-Usak S; Department of Medical Biology, Faculty of Medicine, Bezmialem Vakif University, 34093 Istanbul, Turkey.
Dalli T; Department of Medical Biology, Faculty of Medicine, Bezmialem Vakif University, 34093 Istanbul, Turkey.
Kilic U; Department of Medical Biology, Faculty of Medicine, University of Health Sciences Turkey, 34668 Istanbul, Turkey.
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Dec; Vol. 79, pp. 153324. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Benzoquinones/*pharmacology
Hippocampus/*drug effects
Neuroprotective Agents/*pharmacology
Acetylcholinesterase/metabolism ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/pharmacology ; Animals ; Cell Survival/drug effects ; Disease Models, Animal ; Female ; Gene Expression Regulation/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; MAP Kinase Signaling System/drug effects ; Maze Learning/drug effects ; Memory/drug effects ; Neurons/drug effects ; Peptide Fragments/pharmacology ; Phosphorylation/drug effects ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Pubertal fenvalerate exposure impairs cognitive and behavioral development partially through down-regulating hippocampal thyroid hormone receptor signaling.
Autorzy :
Yang Y; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Zhan F; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Wang YC; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Wang B; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Shi MX; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Guo C; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China.
Xu DX; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, Anhui, China. Electronic address: .
Meng XH; Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 10; Vol. 332, pp. 192-201. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
Thyroid Hormones*
Cognition Disorders/*chemically induced
Hippocampus/*metabolism
Insecticides/*toxicity
Nitriles/*toxicity
Pyrethrins/*toxicity
Signal Transduction/*drug effects
Animals ; Anxiety/chemically induced ; Anxiety/psychology ; Body Weight/drug effects ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/metabolism ; Cognition Disorders/psychology ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Eating/drug effects ; Endocrine Disruptors ; Female ; Hippocampus/drug effects ; Male ; Maze Learning/drug effects ; Mice ; Mice, Inbred ICR ; Neurons/pathology ; Receptors, Thyroid Hormone/drug effects ; Sex Characteristics
Czasopismo naukowe
Tytuł :
Elimination of Calm1 long 3'-UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice.
Autorzy :
Bae B; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Gruner HN; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Lynch M; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Feng T; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
So K; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Oliver D; Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada 89557, USA.
Mastick GS; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Yan W; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.; Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada 89557, USA.
Pieraut S; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
Miura P; Department of Biology, University of Nevada, Reno, Nevada 89557, USA.
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Źródło :
RNA (New York, N.Y.) [RNA] 2020 Oct; Vol. 26 (10), pp. 1414-1430. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
3' Untranslated Regions/*genetics
CRISPR-Cas Systems/*genetics
Calmodulin/*genetics
Ganglia, Spinal/*physiology
Hippocampus/*physiology
Neurons/*physiology
RNA Isoforms/*genetics
RNA, Messenger/*genetics
Animals ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Female ; Gene Editing/methods ; Mice ; Mice, Inbred C57BL ; Polyadenylation/genetics ; Pregnancy
Czasopismo naukowe
Tytuł :
Ryanodine receptors drive neuronal loss and regulate synaptic proteins during epileptogenesis.
Autorzy :
Royero PX; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Higa GSV; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil; Departamento de Fisiologia e Biofísica, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Kostecki DS; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Dos Santos BA; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Almeida C; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Andrade KA; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Kinjo ER; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil.
Kihara AH; Laboratório de Neurogenética, Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil; Departamento de Fisiologia e Biofísica, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: .
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Źródło :
Experimental neurology [Exp Neurol] 2020 May; Vol. 327, pp. 113213. Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hippocampus/*metabolism
Neurons/*metabolism
Ryanodine Receptor Calcium Release Channel/*metabolism
Seizures/*metabolism
Status Epilepticus/*metabolism
Synapsins/*metabolism
Synaptophysin/*metabolism
Animals ; Calcium/metabolism ; Calcium Channel Blockers/pharmacology ; Dantrolene/pharmacology ; Hippocampus/drug effects ; Hippocampus/pathology ; Male ; Neurons/drug effects ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Pilocarpine ; Rats ; Rats, Wistar ; Seizures/chemically induced ; Status Epilepticus/chemically induced ; Synapses/drug effects ; Synapses/metabolism ; Synapses/pathology
Czasopismo naukowe
Tytuł :
The Firing of Theta State-Related Septal Cholinergic Neurons Disrupt Hippocampal Ripple Oscillations via Muscarinic Receptors.
Autorzy :
Ma X; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China.
Zhang Y; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China.
Wang L; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China.
Li N; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China.
Barkai E; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, 3498838 Israel.
Zhang X; State Key Laboratory of Cognitive Neuroscience & Learning, Beijing Normal University, Beijing, 100875, China.
Lin L; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China .; NYU-ECNU Institute of Brain and Cognitive Science, New York University Shanghai, Shanghai, 200062, China.; Tongji University Brain and Spinal Cord Clinical Center, Shanghai, 200062, China.
Xu J; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Life Science, East China Normal University, Shanghai, 200062, China .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Apr 29; Vol. 40 (18), pp. 3591-3603. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials/*physiology
Cholinergic Neurons/*physiology
Hippocampus/*physiology
Receptor, Muscarinic M2/*physiology
Receptor, Muscarinic M4/*physiology
Theta Rhythm/*physiology
Action Potentials/drug effects ; Animals ; Cholinergic Agonists/pharmacology ; Cholinergic Neurons/chemistry ; Cholinergic Neurons/drug effects ; Hippocampus/chemistry ; Hippocampus/drug effects ; Male ; Mice ; Mice, Transgenic ; Muscarinic Antagonists/pharmacology ; Optogenetics/methods ; Organ Culture Techniques ; Receptor, Muscarinic M2/agonists ; Receptor, Muscarinic M2/antagonists & inhibitors ; Receptor, Muscarinic M4/agonists ; Receptor, Muscarinic M4/antagonists & inhibitors ; Receptors, Muscarinic/physiology ; Theta Rhythm/drug effects
Czasopismo naukowe
Tytuł :
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions.
Autorzy :
Ixmatlahua DJ; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico.
Vizcarra B; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico.
Gómez-Lira G; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico.
Romero-Maldonado I; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico.
Ortiz F; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico.
Rojas-Piloni G; Departamento de Neurobiología del Desarrollo y Neurofisiología, Instituto de Neurobiología, Campus UNAM-Juriquilla, Universidad Nacional Autónoma de México, 76230 Querétaro, Mexico.
Gutiérrez R; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 14330 Mexico City, Mexico .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jun 10; Vol. 40 (24), pp. 4661-4672. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electrical Synapses/*physiology
Gap Junctions/*physiology
Glutamic Acid/*metabolism
Hippocampus/*physiology
Nerve Net/*physiology
Neurons/*physiology
Synaptic Transmission/*physiology
Animals ; Cells, Cultured ; Electrical Synapses/metabolism ; Gap Junctions/metabolism ; Hippocampus/metabolism ; Male ; Nerve Net/metabolism ; Neurons/metabolism ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Increasing Durability of Dissociated Neural Cell Cultures Using Biologically Active Coralline Matrix.
Autorzy :
Weiss OE; Department of Molecular Biology, Ariel University.
Hendler RM; Department of Molecular Biology, Ariel University.
Baranes D; Department of Molecular Biology, Ariel University; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Jun 03 (160). Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Cell Culture Techniques/*methods
Hippocampus/*physiopathology
Neurons/*metabolism
Hippocampus/cytology ; Humans ; Microscopy ; Neurons/cytology
Czasopismo naukowe
Tytuł :
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells.
Autorzy :
Gong M; Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Ye S; Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei, Anhui, China.; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Li WX; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China.
Zhang J; Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Liu Y; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Zhu J; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Lv W; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Clinical Research Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang H; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Wang J; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.
Lu A; School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
He K; Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei, Anhui, China.; Department of Biostatistics, School of Life Sciences, Anhui University, Hefei, Anhui, China.; School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
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Źródło :
American journal of physiology. Cell physiology 2020 Jun 01; Vol. 318 (6), pp. C1123-C1135. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Alzheimer Disease/*enzymology
Hippocampus/*enzymology
Neurons/*metabolism
Receptors, Purinergic P2X3/*metabolism
Receptors, Purinergic P2X7/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Cell Line ; Gene Expression Regulation ; Hippocampus/pathology ; Humans ; Mice ; Neurons/pathology ; Proteins/genetics ; Proteins/metabolism ; Receptors, Purinergic P2X3/genetics ; Receptors, Purinergic P2X7/genetics ; Signal Transduction ; Ubiquitin-Protein Ligases/genetics ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Effects of Brain-Derived Mitochondria on the Function of Neuron and Vascular Endothelial Cell After Traumatic Brain Injury.
Autorzy :
Zhang B; Department of General Medicine, Tianjin Medical University General Hospital, Tianjin, China; Department of Medical Cosmetology, Airport Hospital, Tianjin Medical University General Hospital, Tianjin, China.
Gao Y; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China.
Li Q; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China.
Sun D; Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
Dong X; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China.
Li X; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China.
Xin W; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China.
Zhang J; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; Key Laboratory of Post-Neurotrauma Neurorepair and Regeneration in Central Nervous System, Ministry of Education in China and Tianjin Neurological Institute, Tianjin, China. Electronic address: .
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Źródło :
World neurosurgery [World Neurosurg] 2020 Jun; Vol. 138, pp. e1-e9. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*metabolism
Brain Injuries, Traumatic/*therapy
Endothelial Cells/*metabolism
Hippocampus/*physiopathology
Mitochondria/*transplantation
Neovascularization, Physiologic/*physiology
Neurons/*metabolism
Tight Junction Proteins/*metabolism
Animals ; Apoptosis/physiology ; Blood-Brain Barrier/metabolism ; Brain/physiopathology ; Brain Edema/metabolism ; Brain Edema/physiopathology ; Brain Injuries, Traumatic/metabolism ; Brain Injuries, Traumatic/physiopathology ; Cell Hypoxia ; Cell Respiration/physiology ; Disease Models, Animal ; Endothelial Cells/physiology ; Hypoglycemia ; Long-Term Synaptic Depression/physiology ; Mice ; Neuronal Plasticity/physiology ; Neurons/physiology ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
A novel target to reduce microglial inflammation and neuronal damage after deep hypothermic circulatory arrest.
Autorzy :
Liu M; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Li Y; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China; Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Gao S; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Yan S; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Zhang Q; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Liu G; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Ji B; Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. Electronic address: .
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Źródło :
The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2020 Jun; Vol. 159 (6), pp. 2431-2444.e7. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Webcast
MeSH Terms :
RNA Interference*
Circulatory Arrest, Deep Hypothermia Induced/*adverse effects
Cold Shock Proteins and Peptides/*metabolism
Encephalitis/*prevention & control
Hippocampus/*metabolism
Microglia/*metabolism
Neurons/*metabolism
RNA, Small Interfering/*metabolism
RNA-Binding Proteins/*metabolism
Animals ; Cell Death ; Cell Line, Tumor ; Cold Shock Proteins and Peptides/deficiency ; Cold Shock Proteins and Peptides/genetics ; Disease Models, Animal ; Encephalitis/genetics ; Encephalitis/metabolism ; Encephalitis/pathology ; Hippocampus/pathology ; Humans ; Male ; Mice ; Microglia/pathology ; NF-kappa B/metabolism ; Neurons/pathology ; RNA, Small Interfering/genetics ; RNA-Binding Proteins/genetics ; Rats, Sprague-Dawley ; Rats, Transgenic ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Electroacupuncture Promotes Neural Proliferation in Hippocampus of Perimenopausal Depression Rats via Wnt/β-Catenin Signaling Pathway.
Autorzy :
Jing Q; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Ren L; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China. Electronic address: .
Deng X; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Zhang N; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Fu M; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Wang G; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Jiang XR; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Lin SR; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
Ming CR; The State Key Laboratory of Chinese Educational Commission for Viscera Theory and Application of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.
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Źródło :
Journal of acupuncture and meridian studies [J Acupunct Meridian Stud] 2020 Jun; Vol. 13 (3), pp. 94-103. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article
MeSH Terms :
Wnt Signaling Pathway*
Depression/*therapy
Hippocampus/*metabolism
Neurons/*cytology
Perimenopause/*psychology
beta Catenin/*metabolism
Animals ; Cell Proliferation ; Depression/etiology ; Depression/genetics ; Depression/metabolism ; Disease Models, Animal ; Electroacupuncture ; Female ; Glycogen Synthase Kinase 3 beta/genetics ; Glycogen Synthase Kinase 3 beta/metabolism ; Hippocampus/physiopathology ; Humans ; Male ; Neurons/metabolism ; Perimenopause/metabolism ; Rats ; Rats, Sprague-Dawley ; beta Catenin/genetics
Czasopismo naukowe
Tytuł :
Alpha-Synuclein deficiency ameliorates chronic methamphetamine induced neurodegeneration in mice.
Autorzy :
Ding J; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Hu S; Good Clinical Practice Center, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China.
Meng Y; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Li C; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Huang J; School of Forensic Medicine, Kunming Medical University, Kunming 650000, Yunnan, China.
He Y; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Qiu P; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 May 30; Vol. 438, pp. 152461. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nerve Degeneration*
Hippocampus/*metabolism
Neurons/*metabolism
Neurotoxicity Syndromes/*prevention & control
Substantia Nigra/*metabolism
alpha-Synuclein/*deficiency
Animals ; Autophagy ; Axons/metabolism ; Axons/ultrastructure ; Cells, Cultured ; Cyclin-Dependent Kinase 5/metabolism ; Disease Models, Animal ; Glycogen Synthase Kinase 3 beta/metabolism ; Hippocampus/ultrastructure ; Lysosomes/metabolism ; Lysosomes/ultrastructure ; Male ; Methamphetamine ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Neurons/ultrastructure ; Neurotoxicity Syndromes/genetics ; Neurotoxicity Syndromes/metabolism ; Neurotoxicity Syndromes/pathology ; Phosphorylation ; Substantia Nigra/ultrastructure ; Time Factors ; alpha-Synuclein/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Assessing the Expression of Major Histocompatibility Complex Class I on Primary Murine Hippocampal Neurons by Flow Cytometry.
Autorzy :
Funk KE; Department of Biological Sciences, University of North Carolina at Charlotte; .
Lotz SK; Department of Biological Sciences, University of North Carolina at Charlotte.
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 May 19 (159). Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms :
Flow Cytometry/*methods
Hippocampus/*cytology
Histocompatibility Antigens Class I/*metabolism
Neurons/*metabolism
Animals ; Cells, Cultured ; Female ; Hippocampus/embryology ; Mice, Inbred C57BL ; Neurons/cytology
Czasopismo naukowe
Tytuł :
PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer's disease.
Autorzy :
Syeda T; School of Health Sciences, Purdue University, West Lafayette, IN, 47907, United States; Purdue Institute for Integrative Neurosciences, Purdue University, West Lafayette, IN, 47907, United States.
Foguth RM; School of Health Sciences, Purdue University, West Lafayette, IN, 47907, United States; Purdue Institute for Integrative Neurosciences, Purdue University, West Lafayette, IN, 47907, United States.
Llewellyn E; Summer Research Opportunities Program, Purdue, University, West Lafayette, IN, 47907, United States; Department of Biology, Utah Valley University, Orem, Utah, 84058, United States.
Cannon JR; School of Health Sciences, Purdue University, West Lafayette, IN, 47907, United States; Purdue Institute for Integrative Neurosciences, Purdue University, West Lafayette, IN, 47907, United States. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 May 15; Vol. 437, pp. 152436. Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Food Contamination*
Imidazoles*
Alzheimer Disease/*pathology
Hippocampus/*pathology
Neurons/*pathology
Alzheimer Disease/chemically induced ; Alzheimer Disease/metabolism ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Aspartic Acid Endopeptidases/metabolism ; Disease Models, Animal ; Disease Progression ; Hippocampus/metabolism ; Male ; Mice, Inbred C57BL ; Neurons/metabolism ; Oxidative Stress ; Phosphorylation ; Protein Aggregation, Pathological ; Time Factors ; tau Proteins/metabolism
Czasopismo naukowe

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