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Tytuł :
Protecting Connections from Synapse Elimination.
Autorzy :
Sell GL; Center for Neuroscience, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
McAllister AK; Center for Neuroscience, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: .
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Źródło :
Trends in neurosciences [Trends Neurosci] 2020 Nov; Vol. 43 (11), pp. 841-842. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Neurons*
Synapses*
Complement System Proteins ; Microglia
Czasopismo naukowe
Tytuł :
Presynaptically silent synapses are modulated by the density of surrounding astrocytes.
Autorzy :
Oyabu K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Takeda K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Kawano H; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Kubota K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Watanabe T; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Harata NC; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Katsurabayashi S; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. Electronic address: .
Iwasaki K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 76-82. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Synaptic Transmission*
Astrocytes/*physiology
Brain/*cytology
Neurons/*physiology
Synapses/*physiology
Animals ; Astrocytes/pathology ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Female ; Mice, Inbred ICR ; Neurons/pathology ; Phylogeny ; Pregnancy
Czasopismo naukowe
Tytuł :
Neuronal strategies for meeting the right partner during brain wiring.
Autorzy :
Agi E; Freie Universität Berlin, Germany.
Kulkarni A; Freie Universität Berlin, Germany.
Hiesinger PR; Freie Universität Berlin, Germany. Electronic address: .
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Źródło :
Current opinion in neurobiology [Curr Opin Neurobiol] 2020 Aug; Vol. 63, pp. 1-8. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neurons*
Synapses*
Axons ; Brain ; Neurogenesis
Czasopismo naukowe
Tytuł :
Effect of Aβ Oligomers on Neuronal APP Triggers a Vicious Cycle Leading to the Propagation of Synaptic Plasticity Alterations to Healthy Neurons.
Autorzy :
Rolland M; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Powell R; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Jacquier-Sarlin M; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Boisseau S; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Reynaud-Dulaurier R; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Martinez-Hernandez J; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
André L; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Borel E; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France.
Buisson A; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France .
Lanté F; Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jul 01; Vol. 40 (27), pp. 5161-5176. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyloid beta-Peptides/*pharmacology
Amyloid beta-Protein Precursor/*metabolism
Neuronal Plasticity/*drug effects
Neurons/*metabolism
Synapses/*drug effects
Amyloid beta-Protein Precursor/antagonists & inhibitors ; Animals ; Antibodies, Blocking/pharmacology ; Cerebral Cortex/drug effects ; Cerebral Cortex/metabolism ; Extracellular Space/drug effects ; Extracellular Space/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Histidine/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/drug effects ; Patch-Clamp Techniques ; Primary Cell Culture ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor.
Autorzy :
Turner-Evans DB; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA. Electronic address: .
Jensen KT; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA; Computational and Biological Learning Lab, Department of Engineering, University of Cambridge, Cambridge, UK.
Ali S; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Paterson T; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Sheridan A; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Ray RP; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Wolff T; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Lauritzen JS; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Rubin GM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Bock DD; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA; Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
Jayaraman V; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Oct 14; Vol. 108 (1), pp. 145-163.e10. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Head Movements*
Spatial Navigation*
Brain/*ultrastructure
Nerve Net/*ultrastructure
Neurons/*ultrastructure
Synapses/*ultrastructure
Animals ; Drosophila melanogaster ; Microscopy, Confocal ; Microscopy, Electron ; Microscopy, Fluorescence, Multiphoton ; Neural Pathways ; Visual Pathways
Czasopismo naukowe
Tytuł :
Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity.
Autorzy :
van Oostrum M; Neuroscience Center Zurich, Zurich, Switzerland.; Institute of Translational Medicine (ITM), Department of Health Sciences and Technology, ETH Zurich, 8093, Zurich, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
Campbell B; Neuroscience Center Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Seng C; Neuroscience Center Zurich, Zurich, Switzerland.; Laboratory of Neural Connectivity, Faculties of Medicine and Natural Sciences, Brain Research Institute, University of Zurich, Zürich, 8057, Switzerland.
Müller M; Institute of Translational Medicine (ITM), Department of Health Sciences and Technology, ETH Zurich, 8093, Zurich, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
Tom Dieck S; Max Planck Institute for Brain Research, Frankfurt, Germany.
Hammer J; Institute of Translational Medicine (ITM), Department of Health Sciences and Technology, ETH Zurich, 8093, Zurich, Switzerland.
Pedrioli PGA; Institute of Translational Medicine (ITM), Department of Health Sciences and Technology, ETH Zurich, 8093, Zurich, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
Földy C; Neuroscience Center Zurich, Zurich, Switzerland.; Laboratory of Neural Connectivity, Faculties of Medicine and Natural Sciences, Brain Research Institute, University of Zurich, Zürich, 8057, Switzerland.
Tyagarajan SK; Neuroscience Center Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Wollscheid B; Neuroscience Center Zurich, Zurich, Switzerland. .; Institute of Translational Medicine (ITM), Department of Health Sciences and Technology, ETH Zurich, 8093, Zurich, Switzerland. .; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 05; Vol. 11 (1), pp. 4990. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuronal Plasticity*
Membrane Proteins/*metabolism
Neurons/*metabolism
Synapses/*metabolism
Animals ; Cell Membrane/metabolism ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Homeostasis ; Long-Term Potentiation ; Protein Interaction Maps ; Protein Transport ; Proteostasis ; Rats
Czasopismo naukowe
Tytuł :
Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
Autorzy :
Bartels T; UK Dementia Research Institute, Institute of Neurology, University College London, London WC1E 6BT, UK.
De Schepper S; UK Dementia Research Institute, Institute of Neurology, University College London, London WC1E 6BT, UK.
Hong S; UK Dementia Research Institute, Institute of Neurology, University College London, London WC1E 6BT, UK. .
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Źródło :
Science (New York, N.Y.) [Science] 2020 Oct 02; Vol. 370 (6512), pp. 66-69.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alzheimer Disease/*pathology
Amyloid/*metabolism
Macrophages/*metabolism
Microglia/*metabolism
Parkinson Disease/*pathology
Synapses/*pathology
Animals ; Cell Communication ; Humans ; Mice ; Neurons/metabolism ; Synaptosomes/pathology ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Urokinase-Type Plasminogen Activator Protects Cerebral Cortical Neurons from Soluble Aβ-Induced Synaptic Damage.
Autorzy :
Diaz A; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Merino P; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Guo JD; Silvio O. Conte Center for Oxytocin and Social Cognition & Center for Translational Social Neuroscience, Yerkes National Primate Research Center, Atlanta, Georgia 30329.; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30329.
Yepes MA; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
McCann P; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Katta T; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Tong EM; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Torre E; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329.
Rangaraju S; Department of Neurology, Emory University, Atlanta, Georgia 30329.
Yepes M; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329 .; Department of Neurology, Emory University, Atlanta, Georgia 30329.; Department of Neurology, Veterans Affairs Medical Center, Atlanta, Georgia 30033.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 May 20; Vol. 40 (21), pp. 4251-4263. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Amyloid beta-Peptides/*pharmacology
Cerebral Cortex/*drug effects
Neurons/*drug effects
Synapses/*drug effects
Urokinase-Type Plasminogen Activator/*genetics
Urokinase-Type Plasminogen Activator/*pharmacology
Animals ; Cells, Cultured ; Cerebral Cortex/metabolism ; Mice ; Mice, Transgenic ; Neurons/metabolism ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł :
Breakdown of phospholipids and the elevated nitric oxide are involved in M3 muscarinic regulation of acetylcholine secretion in the frog motor synapse.
Autorzy :
Tsentsevitsky AN; Laboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, Federal Research Center ''Kazan Scientific Center of RAS', Kazan, Russia, 2/31 Lobachevsky Street, box 30, Kazan, 420111, Russia. Electronic address: .
Zakyrjanova GF; Laboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, Federal Research Center ''Kazan Scientific Center of RAS', Kazan, Russia, 2/31 Lobachevsky Street, box 30, Kazan, 420111, Russia; Institute of Neuroscience, Kazan State Medial University, Kazan, Russia, 49 Butlerova Street, Kazan, 420012, Russia. Electronic address: .
Petrov AM; Laboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, Federal Research Center ''Kazan Scientific Center of RAS', Kazan, Russia, 2/31 Lobachevsky Street, box 30, Kazan, 420111, Russia; Institute of Neuroscience, Kazan State Medial University, Kazan, Russia, 49 Butlerova Street, Kazan, 420012, Russia. Electronic address: .
Kovyazina IV; Laboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, Federal Research Center ''Kazan Scientific Center of RAS', Kazan, Russia, 2/31 Lobachevsky Street, box 30, Kazan, 420111, Russia. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Apr 09; Vol. 524 (3), pp. 589-594. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine/*metabolism
Motor Neurons/*metabolism
Nitric Oxide/*metabolism
Phospholipids/*metabolism
Ranidae/*metabolism
Receptor, Muscarinic M3/*metabolism
Synapses/*metabolism
Animals ; Cannabinoids/metabolism ; Motor Neurons/drug effects ; Muscarine/pharmacology ; Muscarinic Agonists/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoinositide-3 Kinase Inhibitors/pharmacology ; Synapses/drug effects ; Type C Phospholipases/metabolism
Czasopismo naukowe
Tytuł :
Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson's disease.
Autorzy :
Torre-Muruzabal T; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium.
Devoght J; UHasselt, BIOMED, Hasselt, Belgium.
Van den Haute C; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium.; KU Leuven, Leuven Viral Vector Core, Leuven, Belgium.
Brône B; UHasselt, BIOMED, Hasselt, Belgium.
Van der Perren A; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium.
Baekelandt V; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium. .
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Oct 22; Vol. 7 (1), pp. 160. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons/*physiology
Parkinson Disease/*physiopathology
Substantia Nigra/*physiopathology
Synapses/*physiology
alpha-Synuclein/*metabolism
Action Potentials ; Animals ; Disease Models, Animal ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/physiology ; Female ; Neurons/metabolism ; Parkinson Disease/metabolism ; Rats, Wistar ; Substantia Nigra/metabolism ; Synapses/metabolism
Czasopismo naukowe
Tytuł :
Reaction-diffusion memory unit: Modeling of sensitization, habituation and dishabituation in the brain.
Autorzy :
Carnaghi MM; Department of Nanoscience, Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro, Greensboro, North Carolina, United States of America.
Starobin JM; Department of Nanoscience, Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro, Greensboro, North Carolina, United States of America.
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Źródło :
PloS one [PLoS One] 2019 Dec 05; Vol. 14 (12), pp. e0225169. Date of Electronic Publication: 2019 Dec 05 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Neural Networks, Computer*
Brain/*physiology
Habituation, Psychophysiologic/*physiology
Memory/*physiology
Neurons/*physiology
Synapses/*physiology
Animals ; Interneurons/physiology ; Learning/physiology ; Motor Neurons/physiology ; Sensory Receptor Cells/physiology
Czasopismo naukowe
Tytuł :
Synaptic Inputs to the Mouse Dorsal Vagal Complex and Its Resident Preproglucagon Neurons.
Autorzy :
Holt MK; Florida State University, Department of Psychology and Program in Neuroscience, Tallahassee, Florida 32306-4301.
Pomeranz LE; Laboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York 10065.
Beier KT; University of California at Irvine, Department of Physiology and Biophysics, Irvine, California 92697, and.
Reimann F; Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom CB2 0QQ.
Gribble FM; Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom CB2 0QQ.
Rinaman L; Florida State University, Department of Psychology and Program in Neuroscience, Tallahassee, Florida 32306-4301, .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2019 Dec 04; Vol. 39 (49), pp. 9767-9781. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons/*physiology
Proglucagon/*physiology
Synapses/*physiology
Vagus Nerve/*physiology
Animals ; Axons/physiology ; Female ; Hypothalamus/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Neural Pathways/physiology ; Neurons, Afferent/physiology ; Posterior Horn Cells/physiology ; Reflex, Monosynaptic/physiology ; Restraint, Physical ; Solitary Nucleus/cytology ; Solitary Nucleus/physiology ; Stress, Psychological/physiopathology ; Thalamus/physiology
Czasopismo naukowe
Tytuł :
Flexible neural connectivity under constraints on total connection strength.
Autorzy :
Ocker GK; Allen Institute for Brain Science, Seattle, Washington, United States of America.
Buice MA; Allen Institute for Brain Science, Seattle, Washington, United States of America.; Department of Applied Mathematics, University of Washington, Seattle, Washington, United States of America.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Aug 03; Vol. 16 (8), pp. e1008080. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Models, Neurological*
Nerve Net*/cytology
Nerve Net*/physiology
Synapses/*physiology
Animals ; Drosophila melanogaster ; Larva/cytology ; Larva/physiology ; Mushroom Bodies/cytology ; Mushroom Bodies/physiology ; Neurons/cytology ; Neurons/physiology
Czasopismo naukowe
Tytuł :
Edge of Chaos and Avalanches in Neural Networks with Heavy-Tailed Synaptic Weight Distribution.
Autorzy :
Kuśmierz Ł; Laboratory for Neural Computation and Adaptation, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Ogawa S; Laboratory for Neural Computation and Adaptation, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Toyoizumi T; Laboratory for Neural Computation and Adaptation, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.; Department of Mathematical Informatics, Graduate School of Information Science and Technology, The University of Tokyo, Tokyo 113-8656, Japan.
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Źródło :
Physical review letters [Phys Rev Lett] 2020 Jul 10; Vol. 125 (2), pp. 028101.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Neurological*
Nerve Net/*physiology
Synapses/*physiology
Animals ; Brain/anatomy & histology ; Brain/physiology ; Computer Simulation ; Nerve Net/anatomy & histology ; Neural Pathways/anatomy & histology ; Neural Pathways/physiology ; Neurons/cytology ; Neurons/physiology ; Nonlinear Dynamics
Czasopismo naukowe
Tytuł :
Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease.
Autorzy :
Zhu Q; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
Zhang N; The Teaching and Research Section of Surgery, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, P.R. China.
Hu N; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
Jiang R; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
Lu H; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
Xuan A; Department of Human Anatomy, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
Long D; Department of Human Anatomy, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
Chen Y; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2020 Mar; Vol. 21 (3), pp. 1172-1180. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Alzheimer Disease*/pathology
Alzheimer Disease*/therapy
Cholinergic Neurons*/metabolism
Cholinergic Neurons*/pathology
Learning*
Memory*
Neural Stem Cells*/metabolism
Neural Stem Cells*/pathology
Neural Stem Cells*/transplantation
Presenilin-1*/biosynthesis
Presenilin-1*/genetics
Stem Cell Transplantation*
Synapses*/genetics
Synapses*/metabolism
Synapses*/pathology
Amyloid/genetics ; Amyloid/metabolism ; Animals ; Disease Models, Animal ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Impact of functional synapse clusters on neuronal response selectivity.
Autorzy :
Ujfalussy BB; Laboratory of Neuronal Signaling, Institute of Experimental Medicine, 1083, Budapest, Hungary. .
Makara JK; Laboratory of Neuronal Signaling, Institute of Experimental Medicine, 1083, Budapest, Hungary.
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Źródło :
Nature communications [Nat Commun] 2020 Mar 16; Vol. 11 (1), pp. 1413. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons/*physiology
Synapses/*physiology
Action Potentials ; Animals ; Membrane Potentials ; Mice ; Models, Neurological ; Neuronal Plasticity ; Neurons/chemistry ; Pyramidal Cells/physiology ; Synapses/chemistry
Czasopismo naukowe
Tytuł :
Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum.
Autorzy :
Katona L; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. .
Hartwich K; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Tomioka R; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.; Laboratory for Cortical Organization and Systematics, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan.; Department of Morphological Neural Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Somogyi J; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Roberts JDB; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Wagner K; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Joshi A; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.; Department of Physiology, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA, USA.
Klausberger T; Center for Brain Research, Division of Cognitive Neurobiology, Medical University of Vienna, 1090, Vienna, Austria.
Rockland KS; Laboratory for Cortical Organization and Systematics, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan.; Department of Anatomy and Neurobiology, Boston University School of Medicine, 72 East Concord St., Boston, MA, 02118, USA.
Somogyi P; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. .
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Źródło :
Brain structure & function [Brain Struct Funct] 2020 Mar; Vol. 225 (2), pp. 705-734. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
GABAergic Neurons/*metabolism
Hippocampus/*metabolism
Receptors, Metabotropic Glutamate/*metabolism
Synapses/*metabolism
Synapses/*ultrastructure
Animals ; Female ; GABAergic Neurons/ultrastructure ; Hippocampus/ultrastructure ; Male ; Mice, Inbred C57BL ; Neural Pathways/metabolism ; Neural Pathways/ultrastructure ; Rats, Sprague-Dawley ; Receptor, Muscarinic M2/metabolism
Czasopismo naukowe
Tytuł :
Memristive synapses connect brain and silicon spiking neurons.
Autorzy :
Serb A; Centre for Electronics Frontiers, University of Southampton, Southampton, SO17 1BJ, UK.
Corna A; Biomedical Sciences and Padua Neuroscience Center, University of Padova, Padova, 35131, Italy.
George R; Institute of Circuits and Systems, TU Dresden, Dresden, 01062, Germany.
Khiat A; Centre for Electronics Frontiers, University of Southampton, Southampton, SO17 1BJ, UK.
Rocchi F; Biomedical Sciences and Padua Neuroscience Center, University of Padova, Padova, 35131, Italy.
Reato M; Biomedical Sciences and Padua Neuroscience Center, University of Padova, Padova, 35131, Italy.
Maschietto M; Biomedical Sciences and Padua Neuroscience Center, University of Padova, Padova, 35131, Italy.
Mayr C; Institute of Circuits and Systems, TU Dresden, Dresden, 01062, Germany.
Indiveri G; Institute of Neuroinformatics, University of Zurich and ETH Zurich, Zurich, 8057, Switzerland.
Vassanelli S; Biomedical Sciences and Padua Neuroscience Center, University of Padova, Padova, 35131, Italy. .
Prodromakis T; Centre for Electronics Frontiers, University of Southampton, Southampton, SO17 1BJ, UK. .
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Źródło :
Scientific reports [Sci Rep] 2020 Feb 25; Vol. 10 (1), pp. 2590. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Neurological*
Action Potentials/*physiology
Excitatory Postsynaptic Potentials/*physiology
Long-Term Potentiation/*physiology
Neurons/*physiology
Synapses/*physiology
Animals ; Electronics/methods ; Embryo, Mammalian ; Hippocampus/cytology ; Hippocampus/physiology ; Microelectrodes ; Nerve Net/cytology ; Nerve Net/physiology ; Neural Networks, Computer ; Neurons/cytology ; Primary Cell Culture ; Rats ; Silicon/chemistry ; Titanium/chemistry
Czasopismo naukowe
Tytuł :
Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease.
Autorzy :
De Luca C; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.
Colangelo AM; Laboratory of Neuroscience 'R. Levi-Montalcini', Dept. of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
Virtuoso A; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.
Alberghina L; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
Papa M; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 24; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuronal Plasticity*
Extracellular Matrix/*physiology
Neuroglia/*physiology
Neurons/*physiology
Synapses/*physiology
Systems Biology/*methods
Animals ; Central Nervous System/physiology ; Epilepsy/physiopathology ; Humans ; Neuroglia/cytology ; Neurons/cytology
Czasopismo naukowe

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