Temat: "Neurons" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Rab11a in the spinal cord: an essential contributor to complete Freund's adjuvant-induced inflammatory pain in mice.
Autorzy:: Gu JX; Department of Neurosurgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.
Wang J; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Ma FJ; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.; School of Medicine, Northwest University, Xi'an, China.
Liu MM; Department of Respiratory and Critical Care Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Chen SH; Department of Psychiatry, Xiaogan Mental Health Center, Xiaogan, China.
Wei Y; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.; School of Medicine, Northwest University, Xi'an, China.
Xiao YF; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.; School of Medicine, Northwest University, Xi'an, China.
Lv PY; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.
Liu X; Department of Stomatology, The 960th Hospital of People's Liberation Army, Jinan, Shandong, China.
Qu JQ; Department of Neurosurgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yan XX; Department of Neurosurgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. .
Chen T; Department of Neurosurgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. .; Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2023 Sep 28; Vol. 16 (1), pp. 70. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:: Journal Article
MeSH Terms:: Pain*/complications
Pain*/metabolism
Spinal Cord*/metabolism
Animals ; Mice ; Freund's Adjuvant ; Hyperalgesia/metabolism ; Inflammation/chemically induced ; Neurons/metabolism ; Posterior Horn Cells ; Receptors, N-Methyl-D-Aspartate/metabolism ; RNA, Small Interfering/metabolism ; Spinal Cord Dorsal Horn/metabolism

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Skocz do pozycji: 2.

Tytuł:: Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling.
Autorzy:: Chafaï M; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Delrocq A; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.; Inria Center of University Côte d'Azur, France, Valbonne, France.
Inquimbert P; Université de Strasbourg, CNRS, Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France.
Pidoux L; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Delanoe K; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Toft M; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Brau F; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Lingueglia E; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.
Veltz R; Inria Center of University Côte d'Azur, France, Valbonne, France.
Deval E; Université Côte d'Azur, CNRS, IPMC, LabEx ICST, FHU InovPain, France.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2023 Apr 17; Vol. 19 (4), pp. e1010993. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium*/metabolism
Pain*
Animals ; Rats ; Computer Simulation ; Neurons/physiology ; Peptides ; Apamin/metabolism

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Skocz do pozycji: 3.

Tytuł:: Calcitonin gene related peptide α is dispensable for many danger-related motivational responses.
Autorzy:: Zajdel J; Center of Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden.
Sköld J; Center of Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden.
Jaarola M; Center of Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden.
Singh AK; Center of Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden.
Engblom D; Center of Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Aug 10; Vol. 11 (1), pp. 16204. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Behavior, Animal*
Anorexia/*physiopathology
Calcitonin Gene-Related Peptide/*physiology
Conditioning, Classical/*physiology
Fear/*psychology
Neurons/*pathology
Pain/*pathology
Amygdala/metabolism ; Amygdala/pathology ; Animals ; Avoidant Restrictive Food Intake Disorder ; Eating ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Motivation ; Neurons/metabolism ; Nociception ; Pain/metabolism ; Parabrachial Nucleus/metabolism ; Parabrachial Nucleus/pathology

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Skocz do pozycji: 4.

Tytuł:: Macrophage as a Peripheral Pain Regulator.
Autorzy:: Domoto R; Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan.
Sekiguchi F; Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan.
Tsubota M; Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan.
Kawabata A; Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Jul 24; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neuroimmunomodulation*
Pain Threshold*
Signal Transduction*
Ganglia, Spinal/*metabolism
Macrophages/*metabolism
Neurons/*metabolism
Pain/*metabolism
Animals ; Cell Communication ; Cytokines/metabolism ; Ganglia, Spinal/immunology ; Ganglia, Spinal/physiopathology ; Humans ; Inflammation Mediators/metabolism ; Macrophages/immunology ; Neurons/immunology ; Neuropeptides/metabolism ; Pain/immunology ; Pain/physiopathology ; Phenotype

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Skocz do pozycji: 5.

Tytuł:: Neuron-Glia-Immune Triad and Cortico-Limbic System in Pathology of Pain.
Autorzy:: Murray I; Department of Obstetrics and Gynecology, Center for Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA.
Bhanot G; Department of Obstetrics and Gynecology, Center for Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA.; Eleanor Roosevelt College, University of California San Diego, San Diego, CA 92122, USA.
Bhargava A; Department of Obstetrics and Gynecology, Center for Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Jun 19; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cerebral Cortex/*immunology
Limbic System/*immunology
Microglia/*immunology
Neurons/*immunology
Pain/*immunology
Animals ; Astrocytes/immunology ; Astrocytes/pathology ; Cerebral Cortex/pathology ; Humans ; Limbic System/pathology ; Lymphocyte Activation ; Microglia/pathology ; Neurons/pathology ; Neutrophil Activation ; Neutrophils/immunology ; Neutrophils/pathology ; Pain/pathology ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology

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Skocz do pozycji: 6.

Tytuł:: Presynaptic Inhibition of Pain and Touch in the Spinal Cord: From Receptors to Circuits.
Autorzy:: Comitato A; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Bardoni R; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 02; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: GABAergic Neurons/*metabolism
Neurons, Afferent/*metabolism
Pain/*metabolism
Receptors, GABA/*metabolism
Spinal Cord Dorsal Horn/*physiology
Synaptic Transmission/*physiology
gamma-Aminobutyric Acid/*metabolism
Animals ; Astrocytes/metabolism ; GABA Antagonists/pharmacology ; GABAergic Neurons/drug effects ; Nerve Fibers/metabolism ; Nerve Fibers/physiology ; Pain/physiopathology ; Synaptic Transmission/drug effects

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Skocz do pozycji: 7.

Tytuł:: ATF3-Expressing Large-Diameter Sensory Afferents at Acute Stage as Bio-Signatures of Persistent Pain Associated with Lumbar Radiculopathy.
Autorzy:: Lin JH; Department of Neurosurgery, Taipei Medical University Hospital, Taipei 110301, Taiwan.; Department of Surgery, Division of Neurosurgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.; Taipei Neuroscience Institute, Taipei Medical University, Taipei 110301, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan.
Yu YW; Department of Surgery, Division of Neurosurgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan.
Chuang YC; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan.
Lee CH; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan.
Chen CC; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan.; Neuroscience Program of Academia Sinica, Academia Sinica, Taipei 115201, Taiwan.; Taiwan Mouse Clinic, Biomedical Translation Research Center, Academia Sinica, Taipei 115202, Taiwan.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Apr 23; Vol. 10 (5). Date of Electronic Publication: 2021 Apr 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Activating Transcription Factor 3/*metabolism
Ganglia, Spinal/*pathology
Lumbosacral Region/*pathology
Neurons, Afferent/*pathology
Pain/*diagnosis
Radiculopathy/*complications
Sensory Receptor Cells/*pathology
Activating Transcription Factor 3/genetics ; Animals ; Ganglia, Spinal/injuries ; Ganglia, Spinal/metabolism ; Male ; Neurons, Afferent/metabolism ; Pain/etiology ; Pain/metabolism ; Rats ; Rats, Sprague-Dawley ; Sensory Receptor Cells/metabolism

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Skocz do pozycji: 8.

Tytuł:: Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
Autorzy:: Upadhyay U; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Zhuang GZ; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Diatchenko L; Alan Edwards Centre for Research on Pain, McGill University Department of Anesthesiology, Montreal, Quebec, Canada.
Parisien M; Alan Edwards Centre for Research on Pain, McGill University Department of Anesthesiology, Montreal, Quebec, Canada.
Kang Y; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Sarantopoulos KD; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Martin ER; John T. MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Smith SB; Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States of America.
Maixner W; Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States of America.
Levitt RC; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; John T. MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2019 Jun 14; Vol. 15 (6), pp. e1008226. Date of Electronic Publication: 2019 Jun 14 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers, Tumor/*genetics
Calcium Signaling/*genetics
Inositol 1,4,5-Trisphosphate Receptors/*genetics
Neurons/*metabolism
Pain/*genetics
Alternative Splicing/genetics ; Animals ; Biomarkers, Tumor/pharmacology ; Cerebellum/drug effects ; Cerebellum/metabolism ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/pathology ; Gene Transfer Techniques ; HEK293 Cells ; Humans ; Mice ; Mutation/genetics ; Neurons/pathology ; Organ Specificity ; Pain/pathology ; Peptides/genetics ; Peptides/pharmacology ; Quantitative Trait Loci/genetics ; RNA Splice Sites/genetics ; Sciatic Nerve/drug effects ; Sciatic Nerve/metabolism

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Skocz do pozycji: 9.

Tytuł:: Nogo-A Induced Polymerization of Microtubule Is Involved in the Inflammatory Heat Hyperalgesia in Rat Dorsal Root Ganglion Neurons.
Autorzy:: Chen L; Department of Human Anatomy, Histology & Embryology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Hu Q; Department of Human Anatomy, Histology & Embryology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Liu H; Department of Human Anatomy, Histology & Embryology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Zhao Y; Department of Human Anatomy, Histology & Embryology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Chan SO; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Wang J; Department of Human Anatomy, Histology & Embryology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 26; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Ganglia, Spinal/*metabolism
Hyperalgesia/*metabolism
Neurons/*metabolism
Nogo Proteins/*metabolism
Pain/*metabolism
Animals ; Gene Knockdown Techniques ; Hyperalgesia/genetics ; Inflammation/genetics ; Inflammation/metabolism ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Male ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Nogo Proteins/genetics ; Pain/genetics ; Rats ; Rats, Sprague-Dawley ; Rats, Transgenic ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism

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Skocz do pozycji: 10.

Tytuł:: Presynaptic AMPA Receptors in Health and Disease.
Autorzy:: Zanetti L; Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.; Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Regoni M; Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.; Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Ratti E; Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
Valtorta F; Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.; Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Sassone J; Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.; Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Aug 31; Vol. 10 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Neurons/*physiology
Pain/*physiopathology
Receptors, AMPA/*metabolism
Receptors, Presynaptic/*metabolism
Synapses/*physiology
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*metabolism
Animals ; Humans

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Skocz do pozycji: 11.

Tytuł:: Epithelial Cell Line Derived from Endometriotic Lesion Mimics Macrophage Nervous Mechanism of Pain Generation on Proteome and Metabolome Levels.
Autorzy:: Neuditschko B; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090 Vienna, Austria.
Leibetseder M; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.
Brunmair J; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.
Hagn G; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.
Skos L; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.
Gerner MC; Division of Biomedical Science, University of Applied Sciences, FH Campus Wien, Favoritenstraße 226, 1100 Vienna, Austria.
Meier-Menches SM; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090 Vienna, Austria.; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.
Yotova I; Department of Obstetrics and Gynaecology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.
Gerner C; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2021 Aug 17; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Line*
Endometriosis/*metabolism
Epithelial Cells/*metabolism
Macrophages/*metabolism
Neurons/*metabolism
Pain/*metabolism
Cell Culture Techniques ; Cell Cycle ; Eicosanoids/chemistry ; Female ; Humans ; Inflammation ; Metabolome ; Metabolomics ; Phenotype ; Proteome ; Proteomics/methods ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 12.

Tytuł:: Agent-based modeling of the central amygdala and pain using cell-type specific physiological parameters.
Autorzy:: Miller Neilan R; Department of Mathematics and Computer Science, Duquesne University, Pittsburgh, Pennsylvania, United States of America.
Majetic G; Department of Mathematics and Computer Science, Duquesne University, Pittsburgh, Pennsylvania, United States of America.; Department of Biological Sciences, Duquesne University, Pittsburgh, Pennsylvania, United States of America.; Department of Engineering, Duquesne University, Pittsburgh, Pennsylvania, United States of America.
Gil-Silva M; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, Texas, United States of America.
Adke AP; National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland, United States of America.
Carrasquillo Y; National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland, United States of America.
Kolber BJ; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, Texas, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2021 Jun 08; Vol. 17 (6), pp. e1009097. Date of Electronic Publication: 2021 Jun 08 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: Models, Neurological*
Central Amygdaloid Nucleus/*physiology
Pain/*physiopathology
Animals ; Central Amygdaloid Nucleus/injuries ; Central Amygdaloid Nucleus/physiopathology ; Computational Biology ; Disease Models, Animal ; Dominance, Cerebral/physiology ; Electrophysiological Phenomena ; Humans ; In Vitro Techniques ; Male ; Mice ; Nerve Net/physiology ; Nerve Net/physiopathology ; Neuralgia/physiopathology ; Neurons/classification ; Neurons/physiology ; Protein Kinase C-delta/metabolism ; Somatostatin/metabolism ; Systems Analysis

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Skocz do pozycji: 13.

Tytuł:: Corticotropin-releasing factor neurons in the bed nucleus of the stria terminalis exhibit sex-specific pain encoding in mice.
Autorzy:: Yu W; Department of Pharmacology, School of Medicine, University of North Carolina At Chapel Hill, CB 7178 Thurston Bowles Building, 104 Manning Drive, Chapel Hill, NC, 27599, USA.; Bowles Center for Alcohol Studies, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.; Curriculum in Pharmacology, School of Medicine, University of North Carolina At Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA.
Caira CM; Department of Pharmacology, School of Medicine, University of North Carolina At Chapel Hill, CB 7178 Thurston Bowles Building, 104 Manning Drive, Chapel Hill, NC, 27599, USA.; Bowles Center for Alcohol Studies, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Del R Rivera Sanchez N; Department of Pharmacology, School of Medicine, University of North Carolina At Chapel Hill, CB 7178 Thurston Bowles Building, 104 Manning Drive, Chapel Hill, NC, 27599, USA.; Bowles Center for Alcohol Studies, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Moseley GA; Department of Pharmacology, School of Medicine, University of North Carolina At Chapel Hill, CB 7178 Thurston Bowles Building, 104 Manning Drive, Chapel Hill, NC, 27599, USA.; Bowles Center for Alcohol Studies, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Kash TL; Department of Pharmacology, School of Medicine, University of North Carolina At Chapel Hill, CB 7178 Thurston Bowles Building, 104 Manning Drive, Chapel Hill, NC, 27599, USA. thomas_.; Bowles Center for Alcohol Studies, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA. thomas_.; Curriculum in Pharmacology, School of Medicine, University of North Carolina At Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA. thomas_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 14; Vol. 11 (1), pp. 12500. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Corticotropin-Releasing Hormone/*metabolism
Neurons/*metabolism
Nociception/*physiology
Pain/*physiopathology
Septal Nuclei/*physiology
Animals ; Corticotropin-Releasing Hormone/genetics ; Disease Models, Animal ; Female ; Hot Temperature/adverse effects ; Humans ; Male ; Mice ; Mice, Transgenic ; Optical Imaging ; Pain/etiology ; Septal Nuclei/cytology ; Septal Nuclei/diagnostic imaging ; Sex Factors

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Skocz do pozycji: 14.

Tytuł:: Plectin dysfunction in neurons leads to tau accumulation on microtubules affecting neuritogenesis, organelle trafficking, pain sensitivity and memory.
Autorzy:: Valencia RG; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.
Mihailovska E; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.
Winter L; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.; Neuromuscular Research Department, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Bauer K; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.
Fischer I; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.
Walko G; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.
Jorgacevski J; Laboratory of Neuroendocrinology - Molecular Cell Physiology, Faculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia.; Celica Biomedical Slovenia, Ljubljana, Slovenia.
Potokar M; Laboratory of Neuroendocrinology - Molecular Cell Physiology, Faculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia.; Celica Biomedical Slovenia, Ljubljana, Slovenia.
Zorec R; Laboratory of Neuroendocrinology - Molecular Cell Physiology, Faculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia.; Celica Biomedical Slovenia, Ljubljana, Slovenia.
Wiche G; Max F. Perutz Laboratories, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria.; Pokaż więcej
Źródło:: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2021 Feb; Vol. 47 (1), pp. 73-95. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Memory/*physiology
Neurons/*metabolism
Organelles/*metabolism
Pain/*metabolism
tau Proteins/*metabolism
Animals ; Intermediate Filaments/metabolism ; Mice ; Microtubules/metabolism ; Pain/physiopathology ; Plectin/deficiency

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Skocz do pozycji: 15.

Tytuł:: Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons.
Autorzy:: Chen X; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .
Duan Y; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .; Department of Ophthalmology and Visual Sciences, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
Riley AM; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .
Welch MA; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .
White FA; Department of Anesthesia, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .; Indianapolis VA Medical Center, Indianapolis, IN, 46202, USA. .
Grant MB; Department of Ophthalmology and Visual Sciences, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
Obukhov AG; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Feb 21; Vol. 24 (4), pp. 775. Date of Electronic Publication: 2019 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Calcium/*metabolism
Capsaicin/*pharmacology
Diabetic Neuropathies/*metabolism
Ganglia, Spinal/*drug effects
Neurons/*drug effects
Pain/*metabolism
TRPV Cation Channels/*metabolism
Animals ; Diabetic Neuropathies/genetics ; Diabetic Neuropathies/pathology ; Disease Models, Animal ; Fluoresceins/chemistry ; Fluorescent Dyes/chemistry ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/pathology ; Gene Expression Regulation ; Glucose/pharmacology ; Ion Transport/drug effects ; Male ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/metabolism ; Neurons/pathology ; Optical Imaging ; Pain/genetics ; Pain/physiopathology ; Patch-Clamp Techniques ; Primary Cell Culture ; Reactive Oxygen Species/metabolism ; Single-Cell Analysis ; TRPV Cation Channels/genetics

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Skocz do pozycji: 16.

Tytuł:: Microbes and pain.
Autorzy:: Deng L; Harvard Medical School, Blavatnik Institute, Department of Immunology, Boston, Massachusetts, United States of America.
Chiu IM; Harvard Medical School, Blavatnik Institute, Department of Immunology, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Apr 01; Vol. 17 (4), pp. e1009398. Date of Electronic Publication: 2021 Apr 01 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Bacteria/*pathogenicity
Cough/*microbiology
Host Microbial Interactions/*immunology
Neurons/*virology
Pain/*microbiology
Animals ; Cough/immunology ; Fungi/virology ; Humans ; Pain/immunology

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Skocz do pozycji: 17.

Tytuł:: NFAT5 Deficiency Alleviates Formalin-Induced Inflammatory Pain Through mTOR.
Autorzy:: Gwon DH; Department of Medical Science, School of Medicine, Chungnam National University, Daejeon 35015, Korea.; Department of Anatomy, Brain Research Institute, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kim SI; Department of Medical Science, School of Medicine, Chungnam National University, Daejeon 35015, Korea.; Department of Anatomy, Brain Research Institute, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Lee SH; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Noh C; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kim Y; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Yun S; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Lee WH; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Oh JY; Department of Neuroscience and Physiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Medical Science, School of Medicine, Chungnam National University, Daejeon 35015, Korea.; Department of Anatomy, Brain Research Institute, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Hong J; Department of Neuroscience and Physiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 08826, Korea.
Lee SY; Department of Anesthesiology and Pain Medicine, School of Medicine, Chungnam National University, Daejeon 35015, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 04; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Formaldehyde/*pharmacology
Inflammation/*metabolism
Pain/*chemically induced
Pain/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Transcription Factors/*metabolism
Animals ; Cell Line, Tumor ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; PC12 Cells ; Pain Measurement/methods ; Rats ; Spinal Cord/metabolism ; Up-Regulation/physiology

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Skocz do pozycji: 18.

Tytuł:: The interaction between P2X3 and TRPV1 in the dorsal root ganglia of adult rats with different pathological pains.
Autorzy:: Yu J; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.; Department of Acupuncture and Massage, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Du J; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Fang J; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Liu Y; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Xiang X; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Liang Y; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Shao X; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Fang J; Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.; Pokaż więcej
Źródło:: Molecular pain [Mol Pain] 2021 Jan-Dec; Vol. 17, pp. 17448069211011315.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ganglia, Spinal/*metabolism
Pain/*metabolism
Receptors, Purinergic P2X3/*metabolism
TRPV Cation Channels/*metabolism
Animals ; Behavior, Animal/physiology ; Capsaicin/analogs & derivatives ; Capsaicin/pharmacology ; Ganglia, Spinal/drug effects ; Inflammation/metabolism ; Male ; Neuralgia/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Pain Measurement ; Rats ; Rats, Sprague-Dawley ; Sensory System Agents/pharmacology

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Skocz do pozycji: 19.

Tytuł:: CCL2 facilitates spinal synaptic transmission and pain via interaction with presynaptic CCR2 in spinal nociceptor terminals.
Autorzy:: Ma SB; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.
Xian H; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Wu WB; The Fourth Regiment, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.
Ma SY; The Sixth Regiment, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.
Liu YK; The Second Regiment, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.
Liang YT; The Second Regiment, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.
Guo H; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.; Pain and Related Diseases Research Laboratory, Medical College of Shantou University, Shantou, 515041, China.
Kang JJ; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.
Liu YY; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.
Zhang H; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.; Department of Health Statistics, Fourth Military Medical University, Xi'an, 710032, China.
Wu SX; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China.
Luo C; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China. .
Xie RG; Department of Neurobiology, Fourth Military Medical University, Xi'an, 710032, China. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2020 Nov 23; Vol. 13 (1), pp. 161. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chemokine CCL2/*metabolism
Nociceptors/*metabolism
Pain/*metabolism
Pain/*physiopathology
Presynaptic Terminals/*metabolism
Receptors, CCR2/*metabolism
Spinal Cord/*physiopathology
Synaptic Transmission/*physiology
Animals ; Benzoxazines/pharmacology ; Calcitonin Gene-Related Peptide/metabolism ; Calcium Signaling/drug effects ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Glutamic Acid/metabolism ; Hyperalgesia/complications ; Inflammation/pathology ; Injections, Spinal ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism ; Pain/complications ; Presynaptic Terminals/drug effects ; Protein Binding/drug effects ; Spinal Cord/drug effects ; Spinal Cord/ultrastructure ; Spinal Cord Dorsal Horn/drug effects ; Spinal Cord Dorsal Horn/ultrastructure ; Spiro Compounds/pharmacology ; Synaptic Transmission/drug effects ; Up-Regulation/drug effects

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Skocz do pozycji: 20.

Tytuł:: Dual role of acid-sensing ion channels 3 in rheumatoid arthritis: destruction or protection?
Autorzy:: Yu GM; a Department of Rheumatology , The Affiliated Hospital to Changchun University of Chinese Medicine , Changchun , PR China.
Liu D; a Department of Rheumatology , The Affiliated Hospital to Changchun University of Chinese Medicine , Changchun , PR China.
Yuan N; a Department of Rheumatology , The Affiliated Hospital to Changchun University of Chinese Medicine , Changchun , PR China.
Liu BH; b Department of Emergency , The First Hospital of Jilin University , Changchun , PR China.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2018 Aug; Vol. 40 (4), pp. 273-277. Date of Electronic Publication: 2018 Jul 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Acid Sensing Ion Channels/*immunology
Arthritis, Rheumatoid/*immunology
Gene Expression Regulation/*immunology
Neurons, Afferent/*immunology
Pain/*immunology
Acid Sensing Ion Channels/genetics ; Animals ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/pathology ; Gene Knockdown Techniques ; Humans ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/pathology ; Neurons, Afferent/pathology ; Pain/genetics ; Pain/pathology

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