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Tytuł :
Direct translation of findings in isolated animal preparations to in vivo human motoneuron behaviour is challenging.
Autorzy :
Del Vecchio A; Department of Bioengineering, Imperial College London, London, UK.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Negro F; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Holobar A; Faculty of Electrical Engineering and Computer Science, University of Maribor, Slovenia.
Casolo A; Department of Bioengineering, Imperial College London, London, UK.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Folland JP; School of Sport, Exercise & Health Sciences, Loughborough University, Loughborough, UK.
Felici F; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.
Farina D; Department of Bioengineering, Imperial College London, London, UK.
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Źródło :
The Journal of physiology [J Physiol] 2020 Mar; Vol. 598 (5), pp. 1111-1112. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Letter; Comment
MeSH Terms :
Motor Neurons*
Patient Discharge*
Animals ; Humans ; Muscle Contraction ; Neurons, Efferent
Opinia redakcyjna
Tytuł :
How motoneurones control velocity of tension development.
Autorzy :
Baldissera F; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Campadelli P; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Cavallari P; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Piccinelli L; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
Tesio L; Human Physiology Section of the De.P.T. Università degli Studi di Milano, Via Mangiagalli 32 I-20133, Milano, Italy.
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Źródło :
The Journal of physiology [J Physiol] 2020 Mar; Vol. 598 (5), pp. 1109-1110. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Letter; Comment
MeSH Terms :
Motor Neurons*
Patient Discharge*
Humans ; Neurons, Efferent
Opinia redakcyjna
Tytuł :
PNOC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding.
Autorzy :
Jais A; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Paeger L; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Sotelo-Hitschfeld T; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Bremser S; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Prinzensteiner M; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Klemm P; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Mykytiuk V; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Widdershooven PJM; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Vesting AJ; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Grzelka K; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Minère M; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Cremer AL; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Xu J; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Korotkova T; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Lowell BB; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02215, USA.
Zeilhofer HU; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zurich, Switzerland; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland.
Backes H; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Fenselau H; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Wunderlich FT; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Kloppenburg P; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany. Electronic address: .
Brüning JC; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jun 17; Vol. 106 (6), pp. 1009-1025.e10. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet, High-Fat*
Hyperphagia*
Obesity*
Arcuate Nucleus of Hypothalamus/*physiology
Feeding Behavior/*physiology
GABAergic Neurons/*physiology
Weight Gain/*physiology
Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/metabolism ; GABAergic Neurons/metabolism ; Mice ; Neural Inhibition/physiology ; Neurons/metabolism ; Neurons/physiology ; Optogenetics ; Pro-Opiomelanocortin/metabolism ; Protein Precursors/metabolism ; Receptors, Opioid/metabolism ; Septal Nuclei/physiology
Czasopismo naukowe
Tytuł :
Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover.
Autorzy :
Zhang J; Department of Pathology, University of California, San Francisco, San Francisco, California 94143.; Pathology Service 113B, VA Medical Center, San Francisco, California 94121.
Shang Y; Department of Pathology, University of California, San Francisco, San Francisco, California 94143.
Kamiya S; Department of Pathology, University of California, San Francisco, San Francisco, California 94143.
Kotowski SJ; Department of Neurology, University of California, San Francisco, San Francisco, California 94122, and.; Gladstone Institute of Neurological Disease, San Francisco, California 94158.
Nakamura K; Department of Neurology, University of California, San Francisco, San Francisco, California 94122, and.; Gladstone Institute of Neurological Disease, San Francisco, California 94158.
Huang EJ; Department of Pathology, University of California, San Francisco, San Francisco, California 94143, .; Pathology Service 113B, VA Medical Center, San Francisco, California 94121.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jan 15; Vol. 40 (3), pp. 557-568. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neurons*
Neuroprotective Agents*
Mitochondria/*drug effects
Neurotoxins/*toxicity
Protein-Serine-Threonine Kinases/*genetics
Protein-Serine-Threonine Kinases/*physiology
Ubiquitin-Protein Ligases/*metabolism
Animals ; Dopaminergic Neurons/ultrastructure ; Female ; Fibroblasts/metabolism ; Gene Expression Regulation/genetics ; Male ; Membrane Potential, Mitochondrial/genetics ; Membrane Potential, Mitochondrial/physiology ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/ultrastructure ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Protein Kinases/genetics
Czasopismo naukowe
Tytuł :
Anatomic resolution of neurotransmitter-specific projections to the VTA reveals diversity of GABAergic inputs.
Autorzy :
Soden ME; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Chung AS; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Cuevas B; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Resnick JM; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Awatramani R; Department of Neurology, Northwestern University, Chicago, IL, USA.
Zweifel LS; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. .; Department of Pharmacology, University of Washington, Seattle, WA, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2020 Aug; Vol. 23 (8), pp. 968-980. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
GABAergic Neurons/*metabolism
Synaptic Transmission/*physiology
Ventral Tegmental Area/*metabolism
Animals ; Conditioning, Classical/physiology ; Conditioning, Operant/physiology ; Dopaminergic Neurons/physiology ; Fear/physiology ; Female ; Male ; Mice ; Motor Activity/physiology ; Neural Pathways/metabolism ; Optogenetics ; Reward ; Self Stimulation
Czasopismo naukowe
Tytuł :
Spaced Training Forms Complementary Long-Term Memories of Opposite Valence in Drosophila.
Autorzy :
Jacob PF; Centre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3TA, UK.
Waddell S; Centre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3TA, UK. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jun 17; Vol. 106 (6), pp. 977-991.e4. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Odorants*
Safety*
Avoidance Learning/*physiology
Conditioning, Classical/*physiology
Memory, Long-Term/*physiology
Neurons/*physiology
Animals ; Dopaminergic Neurons/physiology ; Drosophila melanogaster ; Mushroom Bodies/physiology ; Smell ; Time Factors
Czasopismo naukowe
Tytuł :
The lateralization of left hippocampal CA3 during the retrieval of spatial working memory.
Autorzy :
Song D; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Wang D; School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Yang Q; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Yan T; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Wang Z; Advanced Innovation Center for Human Brain Protection, Capital Medical University; The National Clinical Research Center for Geriatric Disease, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yan Y; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Zhao J; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Xie Z; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Liu Y; School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Ke Z; School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Qazi TJ; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Li Y; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Wu Y; Shandong Collaborative Innovation Center for Diagnosis & Treatment and Behavioral Interventions of mental disorders & Shandong Key Laboratory of Behavioral Medicine, Institute of Mental Health, Jining Medical University, Jining, Shandong, 272067, China.
Shi Q; Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing, 100081, China.
Lang Y; Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing, 100081, China.
Zhang H; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Huang T; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Wang C; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Quan Z; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China. .
Qing H; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 09; Vol. 11 (1), pp. 2901. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Memory, Short-Term*
Spatial Memory*
CA3 Region, Hippocampal/*physiology
Neurons/*physiology
Animals ; Behavior, Animal ; Brain Mapping/methods ; Cholinergic Neurons/physiology ; Female ; Male ; Maze Learning ; Mice ; Mice, Inbred C57BL ; Parvalbumins/physiology
Czasopismo naukowe
Tytuł :
Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors.
Autorzy :
Stephenson-Jones M; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Bravo-Rivera C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Ahrens S; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Furlan A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Xiao X; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Fernandes-Henriques C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Li B; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Mar 04; Vol. 105 (5), pp. 921-933.e5. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Punishment*
Reward*
Basal Forebrain/*metabolism
GABAergic Neurons/*metabolism
Glutamic Acid/*metabolism
Motivation/*physiology
Animals ; Avoidance Learning ; Basal Forebrain/cytology ; Behavior, Animal ; Conditioning, Classical ; GABAergic Neurons/cytology ; Mice ; Neurons/cytology ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Muscarinic Inhibition of Hypoglossal Motoneurons: Possible Implications for Upper Airway Muscle Hypotonia during REM Sleep.
Autorzy :
Zhu L; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215 .
Chamberlin NL; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215.
Arrigoni E; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215 .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2019 Oct 02; Vol. 39 (40), pp. 7910-7919. Date of Electronic Publication: 2019 Aug 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Motor Neurons*
Sleep, REM*
Hypoglossal Nerve/*physiopathology
Muscle Hypotonia/*physiopathology
Parasympathetic Nervous System/*physiopathology
Respiratory Muscles/*physiopathology
Animals ; Carbachol/pharmacology ; Channelrhodopsins ; Female ; Glutamates/physiology ; Hypoglossal Nerve/drug effects ; Male ; Mice ; Muscarinic Agonists/pharmacology ; Neurons, Afferent/drug effects ; Neurons, Afferent/physiology ; Optogenetics ; Parasympathetic Nervous System/drug effects ; Patch-Clamp Techniques ; Synapses/drug effects
Czasopismo naukowe
Tytuł :
Goal-Oriented Behaviour: The Ventral Tegmental Area in Motivated Movements.
Autorzy :
Masullo L; Neurobiology Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. Electronic address: .
Tripodi M; Neurobiology Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. Electronic address: .
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Źródło :
Current biology : CB [Curr Biol] 2019 Oct 07; Vol. 29 (19), pp. R922-R925.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
GABAergic Neurons*
Ventral Tegmental Area*
Animals ; Biomechanical Phenomena ; Dopaminergic Neurons ; Goals ; Reward
Czasopismo naukowe
Tytuł :
Toxoplasma gondii infection damages the perineuronal nets in a murine model.
Autorzy :
Meurer YDSR; Universidade Federal da Paraíba, Programa de Pós-Graduação em Neurociência Cognitiva e Comportamento, João Pessoa, PB, Brasil.; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Psicobiologia, Natal, RN, Brasil.
Brito RMM; Universidade Federal do Rio Grande do Norte, Departamento de Microbiologia e Parasitologia, Laboratório de Biologia da Málaria e Toxoplasmose - LABMAT, Natal, RN, Brasil.
da Silva VP; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Psicobiologia, Natal, RN, Brasil.
Andade JMA; Universidade Federal do Rio Grande do Norte, Departamento de Microbiologia e Parasitologia, Laboratório de Biologia da Málaria e Toxoplasmose - LABMAT, Natal, RN, Brasil.
Linhares SSG; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Psicobiologia, Natal, RN, Brasil.
Pereira Junior A; Universidade Federal do Pará, Instituto de Ciências da Sáude, Laboratório de Neuroplasticidade, Belém, PA, Brasil.
de Andrade-Neto VF; Universidade Federal do Rio Grande do Norte, Departamento de Microbiologia e Parasitologia, Laboratório de Biologia da Málaria e Toxoplasmose - LABMAT, Natal, RN, Brasil.
de Sá AL; Universidade Federal do Rio Grande do Norte, Departamento de Microbiologia e Parasitologia, Laboratório de Biologia da Málaria e Toxoplasmose - LABMAT, Natal, RN, Brasil.
Oliveira CBS; Universidade Federal do Rio Grande do Norte, Departamento de Microbiologia e Parasitologia, Laboratório de Biologia da Málaria e Toxoplasmose - LABMAT, Natal, RN, Brasil.
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Źródło :
Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2020 Sep 11; Vol. 115, pp. e200007. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Toxoplasmosis, Animal*
Cerebellum/*metabolism
Extracellular Matrix/*metabolism
Motor Neurons/*cytology
Neurons/*pathology
Toxoplasmosis/*pathology
Animals ; Cerebellum/cytology ; Disease Models, Animal ; Mice ; Motor Neurons/metabolism ; Neurons/metabolism ; Toxoplasma ; Toxoplasmosis/metabolism
Czasopismo naukowe
Tytuł :
Periaqueductal Gray and Rostromedial Tegmental Inhibitory Afferents to VTA Have Distinct Synaptic Plasticity and Opiate Sensitivity.
Autorzy :
St Laurent R; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA.
Martinez Damonte V; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA.
Tsuda AC; Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA.
Kauer JA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94035, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 May 20; Vol. 106 (4), pp. 624-636.e4. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Analgesics, Opioid/*pharmacology
Neuronal Plasticity/*physiology
Neurons, Afferent/*physiology
Periaqueductal Gray/*physiology
Ventral Tegmental Area/*physiology
Animals ; Female ; GABAergic Neurons/drug effects ; GABAergic Neurons/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Morphine/pharmacology ; Neuronal Plasticity/drug effects ; Neurons, Afferent/drug effects ; Periaqueductal Gray/drug effects ; Tegmentum Mesencephali ; Ventral Tegmental Area/drug effects
Czasopismo naukowe
Tytuł :
Contributing mechanisms underlying desensitization of cholecystokinin-induced activation of primary nodose ganglia neurons.
Autorzy :
Kowalski CW; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington.
Lindberg JEM; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington.
Fowler DK; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington.
Simasko SM; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington.
Peters JH; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington.
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Źródło :
American journal of physiology. Cell physiology 2020 Apr 01; Vol. 318 (4), pp. C787-C796. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cholecystokinin/*pharmacology
Neurons, Afferent/*drug effects
Nodose Ganglion/*drug effects
Vagus Nerve/*drug effects
Animals ; Calcium/metabolism ; Neurons/drug effects ; Neurons, Afferent/cytology ; Neurons, Afferent/physiology ; Nodose Ganglion/cytology ; Nodose Ganglion/physiology ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals.
Autorzy :
Liu J; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.
Kim YS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Richardson CE; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Tom A; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Ramakrishnan C; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Birey F; Department of Psychiatry, Stanford University, Stanford, CA 94305, USA.
Katsumata T; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.
Chen S; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.
Wang C; Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley CA 94720, USA.
Wang X; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Joubert LM; Cell Sciences Imaging Facility, Stanford University, Stanford, CA 94305, USA.
Jiang Y; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.
Wang H; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Fenno LE; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Psychiatry, Stanford University, Stanford, CA 94305, USA.
Tok JB; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.
Pașca SP; Department of Psychiatry, Stanford University, Stanford, CA 94305, USA.
Shen K; Department of Biology, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Bao Z; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA. .
Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA. .; Department of Psychiatry, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Mar 20; Vol. 367 (6484), pp. 1372-1376.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Engineering*
Aniline Compounds/*chemistry
Ascorbate Peroxidases/*genetics
Neurons/*physiology
Nitro Compounds/*chemistry
Phenylenediamines/*chemistry
Polymers/*chemistry
Action Potentials ; Animals ; Ascorbate Peroxidases/metabolism ; Caenorhabditis elegans ; Cell Membrane/metabolism ; Cell Survival ; Cells, Cultured ; Electric Conductivity ; HEK293 Cells ; Hippocampus ; Humans ; Membrane Potentials ; Mice ; Motor Neurons/physiology ; Muscle Cells/physiology ; Neurons/enzymology ; Patch-Clamp Techniques ; Polymers/metabolism ; Rats ; Transduction, Genetic
Czasopismo naukowe
Tytuł :
Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus.
Autorzy :
Pamphlett R; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Mak R; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
Lee J; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
Buckland ME; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Harding AJ; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Kum Jew S; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
Paterson DJ; Australian Synchrotron, Clayton, Victoria, Australia.
Jones MWM; Australian Synchrotron, Clayton, Victoria, Australia.
Lay PA; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
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Źródło :
PloS one [PLoS One] 2020 May 19; Vol. 15 (5), pp. e0233300. Date of Electronic Publication: 2020 May 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Locus Coeruleus/*metabolism
Metals, Heavy/*analysis
Neurons/*metabolism
Trace Elements/*analysis
Aged ; Autopsy ; Female ; Heavy Metal Poisoning ; Humans ; Locus Coeruleus/physiology ; Middle Aged ; Motor Neurons/metabolism ; Multiple Sclerosis/metabolism ; Spectrometry, X-Ray Emission/methods ; Spinal Cord
Czasopismo naukowe
Tytuł :
Injury to dopaminergic neurons development via the Lmx1a/Wnt1 autoregulatory loop induced by simazine.
Autorzy :
Li X; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China.
Li J; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China.
Li P; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China.
Jiang Y; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China.
Wu Y; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China.
Li B; Department of Toxicology, College of Public Health, Harbin Medical University, 157 Baojian Street, Harbin, Heilongjiang Province, 150081, PR China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 279-289. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Dopaminergic Neurons/*drug effects
Environmental Pollutants/*toxicity
LIM-Homeodomain Proteins/*metabolism
Prenatal Exposure Delayed Effects/*chemically induced
Simazine/*toxicity
Transcription Factors/*metabolism
Wnt1 Protein/*metabolism
Animals ; Cell Line ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Dose-Response Relationship, Drug ; Embryonic Development/drug effects ; Female ; Mice ; Pregnancy ; Prenatal Exposure Delayed Effects/metabolism ; Prenatal Exposure Delayed Effects/pathology ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment.
Autorzy :
Moyano P; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
García JM; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
García J; Department of Pharmacolgy, Health Sciences School, Alfonso X University, 28691, Madrid, Spain.
Anadon MJ; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28041, Madrid, Spain.
Naval MV; Department of Pharmacology, Pharmacognosy and Botany, Pharmacy School, Complutense University of Madrid, 28040, Madrid, Spain.
Frejo MT; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
Sola E; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28041, Madrid, Spain.
Pelayo A; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28041, Madrid, Spain.
Pino JD; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Oct 15; Vol. 203, pp. 110975. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid beta-Peptides/*metabolism
Basal Forebrain/*drug effects
Cholinergic Neurons/*drug effects
Environmental Pollutants/*toxicity
HSP70 Heat-Shock Proteins/*metabolism
HSP90 Heat-Shock Proteins/*metabolism
Manganese/*toxicity
Proteasome Endopeptidase Complex/*metabolism
tau Proteins/*metabolism
Animals ; Basal Forebrain/metabolism ; Basal Forebrain/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cholinergic Neurons/metabolism ; Cholinergic Neurons/pathology ; Dose-Response Relationship, Drug ; Environmental Pollutants/metabolism ; Manganese/metabolism ; Mice ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
A multilayer circuit architecture for the generation of distinct locomotor behaviors in Drosophila .
Autorzy :
Zarin AA; Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Mark B; Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Cardona A; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.
Litwin-Kumar A; Mortimer B Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, United States.
Doe CQ; Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
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Źródło :
ELife [Elife] 2019 Dec 23; Vol. 8. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Drosophila/*physiology
Locomotion/*physiology
Motor Neurons/*cytology
Motor Neurons/*physiology
Animals ; Cluster Analysis ; Connectome ; Drosophila/embryology ; Drosophila melanogaster/physiology ; Larva/physiology ; Models, Animal ; Muscles/cytology ; Muscles/diagnostic imaging ; Muscles/physiology ; Neurons/cytology ; Neurons/physiology ; Optogenetics ; Synapses/physiology ; Synapses/ultrastructure
Czasopismo naukowe
Tytuł :
Salvianolate reduces neuronal apoptosis by suppressing OGD-induced microglial activation.
Autorzy :
Luan P; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Ding X; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xu J; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Jiang L; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xu Y; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhu Y; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Li R; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhang J; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional, Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118393. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Glucose/*deficiency
Microglia/*drug effects
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Oxygen/*metabolism
Plant Extracts/*pharmacology
Animals ; Cells, Cultured ; Cytokines/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Mice ; Microglia/metabolism ; Microglia/pathology ; Neurons/metabolism ; Neurons/pathology ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł :
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis.
Autorzy :
Pfisterer U; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Petukhov V; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Demharter S; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Meichsner J; Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Thompson JJ; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Batiuk MY; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Asenjo-Martinez A; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Vasistha NA; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Thakur A; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Mikkelsen J; Department of Neurology and Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Adorjan I; Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary.
Pinborg LH; Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, 2200, Copenhagen, Denmark.; Epilepsy Clinic, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, 2200, Copenhagen, Denmark.
Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
von Engelhardt J; Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Khodosevich K; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 07; Vol. 11 (1), pp. 5038. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistant Epilepsy/*genetics
Epilepsy, Temporal Lobe/*genetics
Neurons/*pathology
Temporal Lobe/*pathology
Transcriptome/*genetics
Adolescent ; Adult ; Biopsy ; Case-Control Studies ; Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Datasets as Topic ; Drug Resistant Epilepsy/diagnosis ; Drug Resistant Epilepsy/pathology ; Drug Resistant Epilepsy/surgery ; Epilepsy, Temporal Lobe/diagnosis ; Epilepsy, Temporal Lobe/pathology ; Epilepsy, Temporal Lobe/surgery ; Female ; Glutamic Acid/metabolism ; Humans ; Magnetic Resonance Imaging ; Male ; Microdissection ; Middle Aged ; Models, Genetic ; Nerve Net/metabolism ; Nerve Net/pathology ; Neurons/cytology ; Neurons/metabolism ; RNA-Seq ; Receptors, AMPA/genetics ; Receptors, AMPA/metabolism ; Receptors, Glutamate/genetics ; Receptors, Glutamate/metabolism ; Signal Transduction/genetics ; Single-Cell Analysis ; Temporal Lobe/cytology ; Temporal Lobe/diagnostic imaging ; Temporal Lobe/surgery ; Transcription, Genetic ; Up-Regulation ; Young Adult
Czasopismo naukowe
Tytuł :
Insulin-Like Growth Factor 2 (IGF-2) Regulates Neuronal Density and IGF-2 Distribution Following Hippocampal Intracerebral Hemorrhage.
Autorzy :
Vafaee F; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Zarifkar A; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Emamghoreishi M; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Pharmacology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Namavar MR; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Histomorphometry and Stereology Research center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Shirzad S; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghazavi H; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: .
Mahdavizadeh V; Student Research committee, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105128. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Hemorrhage/*drug therapy
Hippocampus/*drug effects
Insulin-Like Growth Factor II/*administration & dosage
Neurons/*drug effects
Neuroprotective Agents/*administration & dosage
Animals ; Cell Death/drug effects ; Cerebral Hemorrhage/metabolism ; Cerebral Hemorrhage/pathology ; Hippocampus/metabolism ; Hippocampus/pathology ; Insulin-Like Growth Factor II/metabolism ; Male ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/metabolism ; Rats, Sprague-Dawley ; Recombinant Proteins/administration & dosage ; Time Factors ; Tissue Distribution
Czasopismo naukowe
Tytuł :
High-concentration homocysteine inhibits mitochondrial respiration function and production of reactive oxygen species in neuron cells.
Autorzy :
Zhang T; Neurology Department, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Huang D; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000. Electronic address: .
Hou J; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Li J; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Zhang Y; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000; Qinghai Province Research Key Laboratory of Echinococcosis, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Tian M; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000. Electronic address: .
Li Z; Department of Scientific Research Office, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Tie T; Neurology Department, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Cheng Y; Neurology Department, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Su X; Neurology Department, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Man Z; Neurology Department, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000.
Ma Y; Central Laboratory, Affiliated Hospital of Qinghai University, Tongren Road 29, Xining, Qinghai Province, China, 810000. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105109. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Homocysteine/*toxicity
Mitochondria/*drug effects
Neurons/*drug effects
Reactive Oxygen Species/*metabolism
Animals ; Cell Line ; Cell Respiration/drug effects ; Dose-Response Relationship, Drug ; Mice ; Mitochondria/metabolism ; Mitochondria/pathology ; Neurons/metabolism ; Neurons/pathology ; Rats ; Time Factors
Czasopismo naukowe
Tytuł :
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure.
Autorzy :
Meng Y; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Ding J; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Li C; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Fan H; School of Forensic Medicine, Southern Medical University, Guangzhou, China; School of Basic Medicine and Life Science, Hainan Medical University, Haikou, China.
He Y; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Qiu P; School of Forensic Medicine, Southern Medical University, Guangzhou, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 01; Vol. 331, pp. 188-199. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Central Nervous System Stimulants/*toxicity
Exosomes/*metabolism
Methamphetamine/*toxicity
Neurons/*drug effects
Neurotoxicity Syndromes/*metabolism
alpha-Synuclein/*metabolism
Animals ; Astrocytes/immunology ; Astrocytes/metabolism ; Cell Line, Tumor ; Coculture Techniques ; Cytokines/metabolism ; Hippocampus/cytology ; Humans ; Injections, Intraperitoneal ; Male ; Mice, Inbred C57BL ; Neurons/immunology ; Neurons/metabolism ; Neurotoxicity Syndromes/immunology ; Nuclear Receptor Subfamily 4, Group A, Member 2/genetics ; Primary Cell Culture ; Synucleinopathies/immunology ; Synucleinopathies/metabolism
Czasopismo naukowe
Tytuł :
A Systematic Nomenclature for the Drosophila Ventral Nerve Cord.
Autorzy :
Court R; School of Informatics, University of Edinburgh, Edinburgh, EH8 9AB, UK.
Namiki S; HHMI-Janelia Research Campus, Ashburn, VA 20147, USA; RCAST, University of Tokyo, Tokyo 153-8904, Japan.
Armstrong JD; School of Informatics, University of Edinburgh, Edinburgh, EH8 9AB, UK.
Börner J; Biological Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA.
Card G; HHMI-Janelia Research Campus, Ashburn, VA 20147, USA.
Costa M; Virtual Fly Brain, University of Cambridge, Cambridge, CB2 3EJ, UK.
Dickinson M; Division of Biology and Biological Engineering, The California Institute of Technology, Pasadena, CA 91125, USA.
Duch C; iDN, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.
Korff W; HHMI-Janelia Research Campus, Ashburn, VA 20147, USA.
Mann R; Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10027, USA.
Merritt D; School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Murphey RK; Biological Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA.
Seeds AM; Institute of Neurobiology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Shirangi T; Department of Biology, Villanova University, Villanova, PA 19085, USA.
Simpson JH; Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Truman JW; HHMI-Janelia Research Campus, Ashburn, VA 20147, USA; Friday Harbor Laboratories, University of Washington, Friday Harbor, WA 98250, USA.
Tuthill JC; Department of Physiology & Biophysics, University of Washington, Seattle, WA 98195, USA.
Williams DW; Centre for Developmental Neurobiology, King's College London, London WC2R 2LS, UK.
Shepherd D; School of Natural Sciences, Bangor University, Bangor LL57 2UW, Bangor, UK. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Sep 23; Vol. 107 (6), pp. 1071-1079.e2. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Terminology as Topic*
Drosophila melanogaster/*cytology
Ganglia, Invertebrate/*cytology
Nerve Net/*cytology
Neurons/*classification
Animals ; Cell Lineage ; Drosophila melanogaster/physiology ; Ganglia, Invertebrate/physiology ; Nerve Net/physiology ; Neurons/cytology ; Neurons/physiology
Czasopismo naukowe
Tytuł :
Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease.
Autorzy :
Jun H; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA; Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA, USA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA. Electronic address: .
Bramian A; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Soma S; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Saito T; Lab for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama 351-0106, Japan.
Saido TC; Lab for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama 351-0106, Japan.
Igarashi KM; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA; Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA, USA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA; Japan Science and Technology Agency, Tokyo, Japan. Electronic address: .
Pokaż więcej
Źródło :
Neuron [Neuron] 2020 Sep 23; Vol. 107 (6), pp. 1095-1112.e6. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Connectome*
Alzheimer Disease/*physiopathology
CA1 Region, Hippocampal/*physiopathology
Entorhinal Cortex/*physiopathology
Neurons/*classification
Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Protein Precursor/genetics ; Animals ; CA1 Region, Hippocampal/pathology ; Entorhinal Cortex/pathology ; Female ; Gamma Rhythm ; Male ; Mice ; Mice, Inbred C57BL ; Neural Pathways/pathology ; Neural Pathways/physiopathology ; Neurons/pathology ; Neurons/physiology
Czasopismo naukowe

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