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Wyszukujesz frazę ""Neuropeptide Y"" wg kryterium: Temat


Tytuł :
Effects of Nifedipine on Renal and Cardiovascular Responses to Neuropeptide Y in Anesthetized Rats.
Autorzy :
Bischoff A; Arensia Exploratory Medicine GmbH, 20225 Düsseldorf, Germany.
Stickan-Verfürth M; Department of Nephrology and of Particle Therapy, University Hospital Essen, West German Proton Therapy Centre, 45147 Essen, Germany.
Michel MC; Department of Pharmacology, Johannes Gutenberg University, 55131 Mainz, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 24; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Channel Blockers/*pharmacology
Natriuresis/*drug effects
Neuropeptide Y/*metabolism
Nifedipine/*pharmacology
Animals ; Male ; Rats ; Rats, Wistar ; Receptors, G-Protein-Coupled/metabolism ; Receptors, Neuropeptide/metabolism ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
The Role of Neuropeptide Y in the Nucleus Accumbens.
Autorzy :
Tanaka M; Department of Anatomy, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602-8566, Japan.
Yamada S; Department of Anatomy, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602-8566, Japan.
Watanabe Y; Department of Basic Geriatrics, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602-8566, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 07; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuropeptide Y/*metabolism
Nucleus Accumbens/*metabolism
Animals ; Autonomic Nervous System/metabolism ; Humans ; Neurons/metabolism ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
Increase in neuropeptide Y activity impairs social behaviour in association with glutamatergic dysregulation in diabetic mice.
Autorzy :
Ueda D; Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
Yonemochi N; Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
Kamata T; Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
Shibasaki M; Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
Kamei J; Department of Biomolecular Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
Waddington JL; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Ikeda H; Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2021 Feb; Vol. 178 (3), pp. 726-740. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental*
Neuropeptide Y*
Social Behavior*
Animals ; Mice ; Receptors, Neuropeptide Y/agonists ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Streptozocin
Czasopismo naukowe
Tytuł :
Hunger enhances food-odour attraction through a neuropeptide Y spotlight.
Autorzy :
Horio N; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Liberles SD; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature [Nature] 2021 Apr; Vol. 592 (7853), pp. 262-266. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Food*
Odorants*
Hunger/*physiology
Neuropeptide Y/*metabolism
Agouti-Related Protein/metabolism ; Animals ; Female ; Hypothalamus/cytology ; Hypothalamus/metabolism ; Male ; Mice ; Neurons/metabolism ; Optogenetics ; Pheromones/metabolism ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
Photoinduced receptor confinement drives ligand-independent GPCR signaling.
Autorzy :
Sánchez MF; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Els-Heindl S; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, 04109 Leipzig, Germany.
Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, 04109 Leipzig, Germany.
Wieneke R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Tampé R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 Mar 26; Vol. 371 (6536). Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Cell Membrane/*metabolism
Receptors, Neuropeptide Y/*metabolism
Calcium/metabolism ; Calcium Signaling ; Cell Line ; Cell Movement ; Cytosol/metabolism ; Diffusion ; Humans ; Lasers ; Ligands ; Lipids/analysis ; Models, Biological ; Neuropeptide Y/pharmacology ; Receptor Aggregation ; Receptors, Neuropeptide Y/agonists ; Receptors, Neuropeptide Y/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Pathogenic or protective? Neuropeptide Y in amyotrophic lateral sclerosis.
Autorzy :
Clark CM; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Clark RM; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Hoyle JA; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Dickson TC; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Feb; Vol. 156 (3), pp. 273-289. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Amyotrophic Lateral Sclerosis/*metabolism
Neuropeptide Y/*metabolism
Animals ; Humans ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
Protective effect of neuropeptide Y2 receptor activation against methamphetamine-induced brain endothelial cell alterations.
Autorzy :
Ventura F; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Portugal; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal; Coimbra Hospital and University Centre, Coimbra, Portugal.
Muga M; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal.
Coelho-Santos V; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Portugal; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal.
Fontes-Ribeiro CA; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Portugal; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal.
Leitão RA; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Portugal; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal.
Silva AP; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Portugal; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Nov 01; Vol. 334, pp. 53-59. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*blood supply
Central Nervous System Stimulants/*toxicity
Endothelial Cells/*drug effects
Methamphetamine/*toxicity
Oxidative Stress/*drug effects
Receptors, Neuropeptide Y/*agonists
Blood-Brain Barrier/metabolism ; Brain/cytology ; Cell Death/drug effects ; Cell Line ; Dose-Response Relationship, Drug ; Endothelial Cells/metabolism ; Humans ; Microvessels/cytology ; Microvessels/drug effects ; Microvessels/metabolism ; Neuropeptide Y/analogs & derivatives ; Neuropeptide Y/pharmacology ; Peptide Fragments/pharmacology ; Reactive Oxygen Species/metabolism ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Receptors, Neuropeptide Y/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Neuropeptide Y as Alternative Pharmacotherapy for Antidepressant-Resistant Social Fear.
Autorzy :
Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Zoicas I; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 03; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance*/drug effects
Antidepressive Agents/*therapeutic use
Fear/*drug effects
Neuropeptide Y/*therapeutic use
Phobia, Social/*drug therapy
Animals ; Conditioning, Classical/drug effects ; Extinction, Psychological/drug effects ; Female ; Male ; Mice ; Mice, Knockout ; Neuropeptide Y/pharmacology ; Paroxetine/pharmacology ; Paroxetine/therapeutic use ; Receptors, Neuropeptide Y/agonists ; Sphingomyelin Phosphodiesterase/genetics
Czasopismo naukowe
Tytuł :
Neuropeptide Y1 receptor antagonist but not neuropeptide Y itself increased bone mineral density when locally injected with hyaluronic acid in male Wistar rats
Autorzy :
Çevik MÖ; Department of Medical Genetics, Faculty of Medicine, Adıyaman University, Adıyaman, Turkey
Korkusuz P; Department of Histology and Embryology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Korkusuz F; Department of Sports Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey
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Źródło :
Turkish journal of medical sciences [Turk J Med Sci] 2020 Aug 26; Vol. 50 (5), pp. 1454-1460. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Neuropeptide Y*/antagonists & inhibitors
Receptors, Neuropeptide Y*/metabolism
Bone Density/*drug effects
Hyaluronic Acid/*pharmacology
Neuropeptide Y/*metabolism
Animals ; Hyaluronic Acid/administration & dosage ; Male ; Rats ; Rats, Wistar ; Tibia/drug effects ; Tibia/metabolism ; Tibia/pathology
Czasopismo naukowe
Tytuł :
Structural Perspective on Ancient Neuropeptide Y-like System reveals Hallmark Features for Peptide Recognition and Receptor Activation.
Autorzy :
Gershkovich MM; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, 04103 Leipzig, Germany; Department of Chemistry, Center for Structural Biology, Vanderbilt University, 465 21st Ave South, BIOSCI/MRBIII, Nashville, TN 37235, USA.
Groß VE; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Johannisallee 30, 04103 Leipzig, Germany.
Vu O; Department of Chemistry, Center for Structural Biology, Vanderbilt University, 465 21st Ave South, BIOSCI/MRBIII, Nashville, TN 37235, USA.
Schoeder CT; Department of Chemistry, Center for Structural Biology, Vanderbilt University, 465 21st Ave South, BIOSCI/MRBIII, Nashville, TN 37235, USA; Institute for Drug Discovery, Medical Faculty, Leipzig University, Brüderstr. 34, 04103 Leipzig, Germany.
Meiler J; Department of Chemistry, Center for Structural Biology, Vanderbilt University, 465 21st Ave South, BIOSCI/MRBIII, Nashville, TN 37235, USA; Institute for Drug Discovery, Medical Faculty, Leipzig University, Brüderstr. 34, 04103 Leipzig, Germany.
Prömel S; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Johannisallee 30, 04103 Leipzig, Germany.
Kaiser A; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, 04103 Leipzig, Germany. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Jun 25; Vol. 433 (13), pp. 166992. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caenorhabditis elegans/*metabolism
Neuropeptide Y/*chemistry
Neuropeptide Y/*metabolism
Receptors, Neuropeptide Y/*metabolism
Amino Acid Motifs ; Amino Acid Sequence ; Animals ; Binding Sites ; Caenorhabditis elegans Proteins/chemistry ; Caenorhabditis elegans Proteins/metabolism ; Humans ; Models, Molecular ; Mutation/genetics ; Protein Binding ; Receptors, Neuropeptide Y/chemistry
Czasopismo naukowe
Tytuł :
Investigation of the effect of a modified fragment of neuropeptide Y on memory phases and extrapolation escape of animals.
Autorzy :
Student IOHP
Professor SYSMPD
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Transliterated Title :
Výzkum účinku modifikovaného fragmentu neuropeptidu Y na paměťové fáze a extrapolační únikový test zvířat.
Źródło :
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti [Ceska Slov Farm] 2021 Summer; Vol. 70 (3), pp. 93-101.
Typ publikacji :
Journal Article
MeSH Terms :
Neuropeptide Y*/administration & dosage
Neuropeptide Y*/pharmacology
Oligopeptides*/administration & dosage
Oligopeptides*/pharmacology
Peptide Fragments*/administration & dosage
Peptide Fragments*/pharmacology
Escape Reaction/*drug effects
Memory/*drug effects
Amino Acid Sequence ; Animals
Czasopismo naukowe
Tytuł :
Fast A-type currents shape a rapidly adapting form of delayed short latency firing of excitatory superficial dorsal horn neurons that express the neuropeptide Y Y1 receptor.
Autorzy :
Sinha GP; Department of Anesthesiology and Perioperative Medicine, Pittsburgh Center for Pain Research, and the Pittsburgh Project to end Opioid Misuse, University of Pittsburgh, Pittsburgh, PA, USA.
Prasoon P; Department of Anesthesiology and Perioperative Medicine, Pittsburgh Center for Pain Research, and the Pittsburgh Project to end Opioid Misuse, University of Pittsburgh, Pittsburgh, PA, USA.
Smith BN; Department of Neuroscience, University of Kentucky, Lexington, KY, USA.
Taylor BK; Department of Anesthesiology and Perioperative Medicine, Pittsburgh Center for Pain Research, and the Pittsburgh Project to end Opioid Misuse, University of Pittsburgh, Pittsburgh, PA, USA.
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Źródło :
The Journal of physiology [J Physiol] 2021 May; Vol. 599 (10), pp. 2723-2750. Date of Electronic Publication: 2021 Apr 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Action Potentials*
Posterior Horn Cells*
Receptors, Neuropeptide Y*
Animals ; Membrane Potentials ; Mice ; Pain
Czasopismo naukowe
Tytuł :
Brain Region-Dependent Effects of Neuropeptide Y on Conditioned Social Fear and Anxiety-Like Behavior in Male Mice.
Autorzy :
Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Zoicas I; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 02; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anxiety/*metabolism
Brain/*metabolism
Neuropeptide Y/*metabolism
Animals ; Male ; Mice ; Neuropeptide Y/administration & dosage
Czasopismo naukowe
Tytuł :
Shuttling of Peptide-Drug Conjugates by G Protein-Coupled Receptors Is Significantly Improved by Pulsed Application.
Autorzy :
Ziffert I; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Brüderstraße 34, 04103, Leipzig, Germany.
Kaiser A; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Brüderstraße 34, 04103, Leipzig, Germany.
Hoppenz P; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Brüderstraße 34, 04103, Leipzig, Germany.
Mörl K; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Brüderstraße 34, 04103, Leipzig, Germany.
Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Brüderstraße 34, 04103, Leipzig, Germany.
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Źródło :
ChemMedChem [ChemMedChem] 2021 Jan 08; Vol. 16 (1), pp. 164-178. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuropeptide Y/*chemistry
Pharmaceutical Preparations/*chemistry
Receptors, Neuropeptide Y/*metabolism
Arrestin/chemistry ; Arrestin/metabolism ; Cell Line, Tumor ; Drug Carriers/chemistry ; Drug Carriers/metabolism ; Fluorescent Dyes/chemistry ; HEK293 Cells ; Humans ; Ligands ; Microscopy, Confocal ; Neuropeptide Y/metabolism ; Protein Binding ; Receptors, Neuropeptide Y/chemistry
Czasopismo naukowe
Tytuł :
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity.
Autorzy :
Yan C; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Zeng T; Wuhan Union Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Lee K; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Nobis M; Invasion and Metastasis Lab, Cancer Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Loh K; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; St. Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Gou L; Wuhan Union Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xia Z; Wuhan Union Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Gao Z; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Bensellam M; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Institute of Experimental and Clinical Research, Pole of Endocrinology, Diabetes and Nutrition, Université catholique de Louvain, Brussels, Belgium.
Hughes W; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Lau J; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Zhang L; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Ip CK; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Enriquez R; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Gao H; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Wang QP; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Wu Q; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.
Haigh JJ; Research Institute in Oncology and Hematology, Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB, Canada.
Laybutt DR; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Timpson P; Invasion and Metastasis Lab, Cancer Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
Herzog H; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia. .; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia. .
Shi YC; Neuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia. y..; Diabetes and Metabolism Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW, Australia. y..; Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia. y..
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Źródło :
Nature communications [Nat Commun] 2021 May 11; Vol. 12 (1), pp. 2622. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arginine/*analogs & derivatives
Obesity/*prevention & control
Receptors, Neuropeptide Y/*antagonists & inhibitors
Thermogenesis/*drug effects
Adipocytes/drug effects ; Adipocytes/metabolism ; Adipose Tissue, Brown/cytology ; Adipose Tissue, Brown/drug effects ; Adipose Tissue, Brown/metabolism ; Adult ; Animals ; Arginine/pharmacology ; Arginine/therapeutic use ; Biopsy ; Cells, Cultured ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Energy Metabolism/drug effects ; Female ; Humans ; Male ; Mice ; Middle Aged ; Obesity/etiology ; Obesity/metabolism ; Primary Cell Culture ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
Identification of a Suitable Peptidic Molecular Platform for the Development of NPY(Y 1 )R-Specific Imaging Agents.
Autorzy :
Krieger K; Biomedical Chemistry Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Wängler B; Molecular Imaging and Radiochemistry Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Schirrmacher R; Division of Oncological Imaging, Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.
Wängler C; Biomedical Chemistry Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
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Źródło :
ChemMedChem [ChemMedChem] 2020 Sep 03; Vol. 15 (17), pp. 1652-1660. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Development*
Molecular Diagnostic Techniques*
Positron-Emission Tomography*
Breast Neoplasms/*diagnostic imaging
Peptides/*chemistry
Receptors, Neuropeptide Y/*analysis
Female ; Humans ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; Molecular Structure ; Neuropeptide Y/chemistry ; Peptides/chemical synthesis
Czasopismo naukowe
Tytuł :
Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses.
Autorzy :
Gonzalez-Montelongo MDC; Biomedical Research Centre, School of Biological Sciences, University of East Anglia, Norwich, UK.
Fountain SJ; Biomedical Research Centre, School of Biological Sciences, University of East Anglia, Norwich, UK. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2021 Feb; Vol. 136, pp. 106810. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mesenteric Arteries/*innervation
Neuropeptide Y/*pharmacology
Receptors, Neuropeptide Y/*agonists
Receptors, Purinergic P2X1/*metabolism
Sympathetic Nervous System/*drug effects
Vasoconstriction/*drug effects
Adenosine Triphosphate/analogs & derivatives ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/pharmacology ; Adrenergic alpha-1 Receptor Antagonists/pharmacology ; Animals ; Benzenesulfonates/pharmacology ; Calcium Channel Blockers/pharmacology ; Calcium Channels, L-Type/drug effects ; Calcium Channels, L-Type/metabolism ; Male ; Mice, Inbred C57BL ; Nifedipine/pharmacology ; Prazosin/pharmacology ; Receptors, Neuropeptide Y/metabolism ; Suramin/pharmacology ; Sympathetic Nervous System/metabolism
Czasopismo naukowe
Tytuł :
Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model.
Autorzy :
Souza-Silva E; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Stein T; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Mascarin LZ; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Dornelles FN; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Bicca MA; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Tonussi CR; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil. Electronic address: .
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Źródło :
Brain research [Brain Res] 2020 May 15; Vol. 1735, pp. 146757. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuropeptide Y/*metabolism
Nociception/*drug effects
Pyridines/*pharmacology
Analgesics/pharmacology ; Animals ; Arthralgia/drug therapy ; Hindlimb/physiology ; Injections, Intra-Articular ; Injections, Spinal ; Knee Joint/drug effects ; Knee Joint/physiology ; Male ; Neuropeptide Y/administration & dosage ; Pain/drug therapy ; Pain Measurement ; Pyridines/metabolism ; Rats ; Rats, Wistar ; Receptors, Histamine/metabolism ; Receptors, Neuropeptide Y/agonists ; Receptors, Neuropeptide Y/analysis ; Spinal Cord/drug effects ; Spine/drug effects
Czasopismo naukowe
Tytuł :
Neuropeptide Y neurons in the nucleus accumbens modulate anxiety-like behavior.
Autorzy :
Yamada S; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Islam MS; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
van Kooten N; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Bovee S; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Oh YM; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Tsujimura A; Department of Basic Geriatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Watanabe Y; Department of Basic Geriatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Tanaka M; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan. Electronic address: .
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Źródło :
Experimental neurology [Exp Neurol] 2020 May; Vol. 327, pp. 113216. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anxiety/*metabolism
Behavior, Animal/*physiology
Neurons/*metabolism
Neuropeptide Y/*metabolism
Nucleus Accumbens/*metabolism
Animals ; Anxiety/genetics ; Mice ; Mice, Transgenic ; Motor Activity/physiology ; Neuropeptide Y/genetics ; Receptors, Neuropeptide Y/metabolism
Czasopismo naukowe
Tytuł :
Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y.
Autorzy :
Hoang JD; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.; UCLA Molecular Cellular and Integrative Physiology Interdepartmental Program, UCLA, Los Angeles, California, USA.
Salavatian S; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.
Yamaguchi N; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.
Swid MA; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.
David H; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.
Vaseghi M; UCLA Cardiac Arrhythmia Center.; Neurocardiology Center for Excellence, and.; UCLA Molecular Cellular and Integrative Physiology Interdepartmental Program, UCLA, Los Angeles, California, USA.
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Źródło :
JCI insight [JCI Insight] 2020 Jun 04; Vol. 5 (11). Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Tachycardia, Ventricular*/drug therapy
Tachycardia, Ventricular*/metabolism
Tachycardia, Ventricular*/pathology
Action Potentials/*drug effects
Adrenergic beta-Antagonists/*pharmacology
Arginine/*analogs & derivatives
Neuropeptide Y/*metabolism
Sympathetic Nervous System/*metabolism
Animals ; Arginine/pharmacology ; Disease Models, Animal ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Receptors, Neuropeptide Y/metabolism ; Sus scrofa ; Sympathetic Nervous System/pathology
Czasopismo naukowe

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