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Tytuł:
Neuroprotection by Skimmianine in Lipopolysaccharide-Activated BV-2 Microglia.
Autorzy:
Ogunrinade FA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Iwuanyanwu VU; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Sarker SD; Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.
Olajide OA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 30; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotection*
Quinolines*/pharmacology
Cell Line ; Culture Media, Conditioned/pharmacology ; Cyclooxygenase 2/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Microglia ; NF-kappa B/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection.
Autorzy:
Lachance V; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Bélanger SM; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Hay C; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Le Corvec V; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Banouvong V; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Lapalme M; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Tarmoun K; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.
Beaucaire G; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.
Lussier MP; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.; Département de Chimie, Université du Québec à Montréal, 2101, Rue Jeanne-Mance, Montréal, QC H2X 2J6, Canada.
Kourrich S; Département des Sciences Biologiques, Université du Québec à Montréal, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3X8, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois, Pavillon des Sciences biologiques, 141 Avenue du Président-Kennedy, Montréal, QC H2X 3Y7, Canada.; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Endoplasmic Reticulum*/genetics
Endoplasmic Reticulum*/metabolism
Mitochondria*/genetics
Mitochondria*/metabolism
Neurodegenerative Diseases*/genetics
Neurodegenerative Diseases*/metabolism
Neuroprotection*/genetics
Neuroprotection*/physiology
Receptors, sigma*/genetics
Receptors, sigma*/metabolism
Humans ; Autophagy/genetics ; Autophagy/physiology ; Endoplasmic Reticulum Stress/genetics ; Endoplasmic Reticulum Stress/physiology ; Nuclear Envelope/genetics ; Nuclear Envelope/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Suppression of Chronic Unpredictable Stress-Persuaded Increased Monoamine Oxidase Activity by Taurine Promotes Significant Neuroprotection in Zebrafish Brain.
Autorzy:
Pradhan LK; Neurobiology Laboratory, Centre for Biotechnology, Siksha 'O' Anusandhan (Deemed to Be University), Kalinga Nagar, Bhubaneswar, 751003, India.
Sahoo PK; Neurobiology Laboratory, Centre for Biotechnology, Siksha 'O' Anusandhan (Deemed to Be University), Kalinga Nagar, Bhubaneswar, 751003, India.
Sarangi P; Neurobiology Laboratory, Centre for Biotechnology, Siksha 'O' Anusandhan (Deemed to Be University), Kalinga Nagar, Bhubaneswar, 751003, India.
Chauhan NR; Infectious Disease Biology Division, Institute of Life Sciences, Bhubaneswar, 751023, India.
Das SK; Neurobiology Laboratory, Centre for Biotechnology, Siksha 'O' Anusandhan (Deemed to Be University), Kalinga Nagar, Bhubaneswar, 751003, India. .
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Źródło:
Neurochemical research [Neurochem Res] 2023 Jan; Vol. 48 (1), pp. 82-95. Date of Electronic Publication: 2022 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Zebrafish*
Neuroprotection*
Animals ; Taurine/pharmacology ; Brain ; Monoamine Oxidase
Czasopismo naukowe
Szczegóły
Tytuł:
School readiness of children at high risk of cerebral palsy r andomised to early neuroprotection and neurorehabilitation: protocol for a follow-up study of participants from four randomised clinical trials.
Autorzy:
Boyd RN; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia .
Novak I; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Morgan C; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Bora S; Case Western Reserve University School of Medicine, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, Ohio, USA.; Faculty of Medicine, Mater Research Institute, The University of Queensland, South Brisbane, Queensland, Australia.
Sakzewski L; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Ware RS; Menzies Health Institute Queensland, Griffith University, Nathan, Queensland, Australia.
Comans T; Centre for Health Services Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Fahey MC; Paediatric Neurology, Monash Medical Centre Clayton, Clayton, Victoria, Australia.; Paediatrics, Monash University, Clayton, Victoria, Australia.
Whittingham K; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Trost S; School of Human Movement and Nutrition Sciences, The University of Queensland, Saint Lucia, Queensland, Australia.
Pannek K; The Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Canberra, Australian Capital Territory, Australia.
Pagnozzi A; The Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Canberra, Australian Capital Territory, Australia.
Mcintyre S; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Badawi N; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Smithers Sheedy H; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Palmer KR; Obstetrics and Gynaecology, Monash University School of Clinical Sciences at Monash Health, Clayton, Victoria, Australia.
Burgess A; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Keramat A; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Bell K; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.; Dietetics and Food Services, Children's Health Queensland, South Brisbane, Queensland, Australia.
Hines A; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.
Benfer K; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Gascoigne-Pees L; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Leishman S; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
Oftedal S; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, The University of Queensland Child Health Research Centre, South Brisbane, Queensland, Australia.
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Źródło:
BMJ open [BMJ Open] 2023 Feb 27; Vol. 13 (2), pp. e068675. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroprotection*
Cerebral Palsy*
Infant ; Humans ; Child ; Child, Preschool ; Follow-Up Studies ; Hospitals, Pediatric ; Schools ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Szczegóły
Tytuł:
Enhancing the Neuroprotection Potential of Edaravone in Transient Global Ischemia Treatment with Glutathione- (GSH-) Conjugated Poly(methacrylic acid) Nanogel as a Promising Carrier for Targeted Brain Drug Delivery.
Autorzy:
Mozafari F; Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.; Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Rashidzadeh H; Pharmaceutical Biotechnology Research Center, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.; Pharmaceutical Biomaterials Department, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Bijani S; Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Zare-Molaei F; Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Islambulchilar Z; Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Danafar H; Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Kalantari-Hesari A; Department of Pathobiology, Faculty of Veterinary Sciences, Bu-Ali Sina University, Hamedan, Iran.
Ramazani A; Pharmaceutical Biotechnology Research Center, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.; Pharmaceutical Biomaterials Department, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Hosseini MJ; Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
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Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2023 Feb 21; Vol. 2023, pp. 7643280. Date of Electronic Publication: 2023 Feb 21 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotection*
Ischemic Stroke*
Rats ; Animals ; Rats, Wistar ; Edaravone/pharmacology ; Edaravone/therapeutic use ; Nanogels ; Brain ; Glutathione ; Ischemia ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Acute Disease
Czasopismo naukowe
Szczegóły
Tytuł:
Natural Products as Modulators of Nrf2 Signaling Pathway in Neuroprotection.
Autorzy:
Moratilla-Rivera I; Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.
Sánchez M; Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.
Valdés-González JA; Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.
Gómez-Serranillos MP; Departamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 13; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biological Products*/pharmacology
Neuroprotection*/drug effects
NF-E2-Related Factor 2*/drug effects
NF-E2-Related Factor 2*/metabolism
Animals ; Mice ; Anthocyanins/metabolism ; Antioxidants/pharmacology ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of RRM, RGG and Potential Phosphorylated Sites in Cold-Inducible Protein RBM3 on its Subcellular Localization and Neuroprotective Effects.
Autorzy:
Wang L; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Shao TC; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Wang CY; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Li JJ; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Jian SQ; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Wang D; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
Cheng BF; College of Life Science and Technology, Xinxiang Medical University, 453003 Xinxiang, Henan, China.
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Źródło:
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2023 Feb 08; Vol. 28 (2), pp. 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA-Binding Proteins*/genetics
Neuroprotection*
Humans ; Arginine ; Cytoplasm ; Cell Line, Tumor
Czasopismo naukowe
Szczegóły
Tytuł:
Synthesis and Pharmacological Evaluation of Novel Triazole-Pyrimidine Hybrids as Potential Neuroprotective and Anti-neuroinflammatory Agents.
Autorzy:
Manzoor S; Drug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia Central University, New Delhi, India, 110025.
Almarghalani DA; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH, 43614, USA.
James AW; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH, 43614, USA.
Raza MK; Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India.
Kausar T; Department of Chemistry, Aligarh Muslim University, Aligarh, UP, 202002, India.
Nayeem SM; Department of Chemistry, Aligarh Muslim University, Aligarh, UP, 202002, India.
Hoda N; Drug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia Central University, New Delhi, India, 110025. .
Shah ZA; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH, 43614, USA. .
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Źródło:
Pharmaceutical research [Pharm Res] 2023 Jan; Vol. 40 (1), pp. 167-185. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotection*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Humans ; NF-kappa B/metabolism ; Triazoles/pharmacology ; Triazoles/metabolism ; Molecular Docking Simulation ; Anti-Inflammatory Agents/pharmacology ; Microglia/pathology ; Pyrimidines/pharmacology ; Pyrimidines/metabolism ; Lipopolysaccharides/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Sigma-1 receptor-regulated efferocytosis by infiltrating circulating macrophages/microglial cells protects against neuronal impairments and promotes functional recovery in cerebral ischemic stroke.
Autorzy:
Zhang G; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Li Q; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Tao W; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Qin P; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Chen J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Yang H; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Chen J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Liu H; Department of Neurobiology, Hai'an Hospital of Traditional Chinese Medicine, Hai'an 226600, China.
Dai Q; Department of Neurobiology, Hai'an Hospital of Traditional Chinese Medicine, Hai'an 226600, China.
Zhen X; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
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Źródło:
Theranostics [Theranostics] 2023 Jan 01; Vol. 13 (2), pp. 543-559. Date of Electronic Publication: 2023 Jan 01 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ischemic Stroke*/pathology
Apoptosis*
Neuroprotection*
Animals ; Mice ; Macrophages/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/metabolism ; Neurons/pathology
Czasopismo naukowe
Szczegóły
Tytuł:
3-Bromopyruvate, a caloric restriction mimetic, exerts a mitohormetic effect to provide neuroprotection through activation of autophagy in rats during aging.
Autorzy:
Arya JK; Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, 211002, India.
Kumar R; Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, 211002, India.
Tripathi SS; Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, 211002, India.
Rizvi SI; Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, 211002, India. .
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Źródło:
Biogerontology [Biogerontology] 2022 Oct; Vol. 23 (5), pp. 641-652. Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Caloric Restriction*
Neuroprotection*
Aging/metabolism ; Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Autophagy ; Biomarkers/metabolism ; Male ; Oxidative Stress ; Pyruvates ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Neurotrophic and immunomodulatory effects of olfactory ensheathing cells as a strategy for neuroprotection and regeneration.
Autorzy:
Denaro S; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
D'Aprile S; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Alberghina C; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Pavone AM; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Torrisi F; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Giallongo S; Section of Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Longhitano L; Section of Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Mannino G; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.
Lo Furno D; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Zappalà A; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Giuffrida R; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Tibullo D; Section of Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Li Volti G; Section of Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Vicario N; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Parenti R; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 19; Vol. 13, pp. 1098212. Date of Electronic Publication: 2022 Dec 19 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroprotection*
Neuroglia*/physiology
Schwann Cells ; Astrocytes ; Cell- and Tissue-Based Therapy
Czasopismo naukowe
Szczegóły
Tytuł:
Role of Bioactive Molecules on Neuroprotection, Oxidative Stress, and Neuroinflammation Modulation.
Autorzy:
Di Liberto V; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Università di Palermo, Corso Tukory 129, 90134 Palermo, Italy.
Mudò G; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Università di Palermo, Corso Tukory 129, 90134 Palermo, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 14; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:
Editorial
MeSH Terms:
Neuroprotection*
Neuroinflammatory Diseases*
Humans ; Oxidative Stress
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
σ 2 R/TMEM97 in retinal ganglion cell degeneration.
Autorzy:
Wang H; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Peng Z; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Li Y; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Sahn JJ; Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX, 78712, USA.
Hodges TR; Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX, 78712, USA.
Chou TH; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Liu Q; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Zhou X; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Jiao S; Department of Biomedical Engineering, Florida International University, Miami, FL, 33174, USA.
Porciatti V; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Liebl DJ; Department of Neurosurgery, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
Martin SF; Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX, 78712, USA. .
Wen R; Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 01; Vol. 12 (1), pp. 20753. Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Retinal Ganglion Cells*
Neuroprotection*
Animals ; Mice ; Endoplasmic Reticulum ; Intravitreal Injections
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Taking Stock After Another Negative Erythropoietin Neuroprotection Trial.
Autorzy:
Wood TR; Division of Neonatology, Pediatrics, University of Washington, Seattle.
Juul SE; Division of Neonatology, Pediatrics, University of Washington, Seattle.
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Źródło:
JAMA network open [JAMA Netw Open] 2022 Dec 01; Vol. 5 (12), pp. e2247054. Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Erythropoietin*/therapeutic use
Neuroprotection*
Humans ; Clinical Trials as Topic
Czasopismo naukowe
Szczegóły
Tytuł:
The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling.
Autorzy:
Gayen M; Department of Neuroscience, University of Connecticut Health, Farmington, Connecticut, USA.
Benoit MR; Department of Neuroscience, University of Connecticut Health, Farmington, Connecticut, USA.
Fan Q; Department of Neuroscience, University of Connecticut Health, Farmington, Connecticut, USA.
Hudobenko J; Department of Neuroscience, University of Connecticut Health, Farmington, Connecticut, USA.
Yan R; Department of Neuroscience, University of Connecticut Health, Farmington, Connecticut, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102532. Date of Electronic Publication: 2022 Sep 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemokine CX3CL1*/genetics
Chemokine CX3CL1*/metabolism
Neuroprotection*
Receptor, Insulin*/genetics
Receptor, Insulin*/metabolism
Receptors, Somatomedin*/genetics
Receptors, Somatomedin*/metabolism
Animals ; Mice ; Amyloid Precursor Protein Secretases/genetics ; Amyloid Precursor Protein Secretases/metabolism ; CX3C Chemokine Receptor 1 ; Mice, Transgenic
Czasopismo naukowe
Szczegóły
Tytuł:
"POLAR-izing" Findings From Trials of Neuroprotection for Oxaliplatin Neuropathy.
Autorzy:
Teng C; Faculty of Medicine and Health, University of Sydney, Sydney, Australia.; Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, Australia.
Vardy JL; Faculty of Medicine and Health, University of Sydney, Sydney, Australia.; Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, Australia.
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Źródło:
JNCI cancer spectrum [JNCI Cancer Spectr] 2022 Nov 01; Vol. 6 (6).
Typ publikacji:
Editorial; Comment
MeSH Terms:
Neuroprotection*
Peripheral Nervous System Diseases*/chemically induced
Humans ; Oxaliplatin/adverse effects ; Pyridoxal Phosphate/adverse effects
Opinia redakcyjna
Szczegóły
Tytuł:
The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection.
Autorzy:
Kirchenwitz M; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.; Division of Molecular Cell Biology, Zoological Institute, Technische Universität Braunschweig, Spielmannstrasse 7, 38106, Braunschweig, Germany.
Stahnke S; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
Grunau K; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.; Division of Cellular and Molecular Neurobiology, Technische Universität Braunschweig, Spielmannstrasse 7, 38106, Braunschweig, Germany.
Melcher L; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
van Ham M; Cellular Proteome Research, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
Rottner K; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.; Division of Molecular Cell Biology, Zoological Institute, Technische Universität Braunschweig, Spielmannstrasse 7, 38106, Braunschweig, Germany.
Steffen A; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany. .
Stradal TEB; Department of Cell Biology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 25; Vol. 12 (1), pp. 17805. Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroprotection*
Neuroprotective Agents*/pharmacology
Neurotoxins/pharmacology ; Autophagy ; TOR Serine-Threonine Kinases/metabolism ; Sirolimus/pharmacology ; Microtubules/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Overexpression of Brain- and Glial Cell Line-Derived Neurotrophic Factors Is Neuroprotective in an Animal Model of Acute Hypobaric Hypoxia.
Autorzy:
Gavrish MS; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Urazov MD; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Mishchenko TA; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Turubanova VD; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Epifanova EA; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Krut' VG; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.; Scientific Center for Genetics and Life Sciences, Sirius University of Science and Technology, 354340 Sochi, Russia.
Babaev AA; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Vedunova MV; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
Mitroshina EV; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarina Ave., 603022 Nizhny Novgorod, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 27; Vol. 23 (17). Date of Electronic Publication: 2022 Aug 27.
Typ publikacji:
Journal Article
MeSH Terms:
Glial Cell Line-Derived Neurotrophic Factor*/metabolism
Neuroprotection*
Brain-Derived Neurotrophic Factor/*metabolism
Hypoxia/*metabolism
Animals ; Brain/metabolism ; Cells, Cultured ; Hypoxia/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury.
Autorzy:
Taylor MJ; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Thompson AM; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Alhajlah S; Applied Medical Science College, Shaqra University, Addawadmi, Riyadh, Saudi Arabia.
Tuxworth RI; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Ahmed Z; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.; Centre for Trauma Sciences Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
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Źródło:
Science advances [Sci Adv] 2022 Sep 16; Vol. 8 (37), pp. eabq2611. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Neuroprotection*
Animals ; Axons ; Checkpoint Kinase 1 ; Nerve Regeneration ; Rats
Czasopismo naukowe
Szczegóły
Tytuł:
Possible Involvement of DNA Methylation in TSC1 Gene Expression in Neuroprotection Induced by Hypoxic Preconditioning.
Autorzy:
Qi R; Department of Basic Medicine and Forensic Medicine, Baotou Medical College of Inner Mongolia University of Science and Technology, Baotou, China.; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xie Y; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zhang X; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Department of Neurosurgery, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia, China.
Jiang S; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Liu X; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xie W; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jia X; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Bade R; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Liu Y; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.; Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Gong K; Department of Oral and Maxillofacial Surgery, University of California san Francisco, San Francisco, USA.
Yang W; Inner Mongolia Key Laboratory of Hypoxic Translational Medicine, Baotou Medical College, Baotou, China.
Guo G; Center for Translational Medicine and Department of Laboratory Medicine, The Third People's Hospital of Longgang District, Shenzhen, China.
Sun K; Center for Translational Medicine and Department of Laboratory Medicine, The Third People's Hospital of Longgang District, Shenzhen, China.
Zhang C; Department of Neurosurgery, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia, China.
Han R; Department of Cardiology, The People's Hospital of Longgang District, Shenzhen, China.
Shao G; Center for Translational Medicine and Department of Laboratory Medicine, The Third People's Hospital of Longgang District, Shenzhen, China.
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Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Sep 09; Vol. 2022, pp. 9306097. Date of Electronic Publication: 2022 Sep 09 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotection*/genetics
Ribosomal Protein S6 Kinases, 70-kDa*/metabolism
Adenosine Triphosphate/metabolism ; Animals ; DNA Methylation/genetics ; Gene Expression ; Hypoxia/genetics ; Hypoxia/metabolism ; Methyltransferases/metabolism ; Mice ; Reactive Oxygen Species ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Szczegóły
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