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Wyszukujesz frazę ""Neuroprotection"" wg kryterium: Temat


Tytuł :
Crosstalk between Neuron and Glial Cells in Oxidative Injury and Neuroprotection.
Autorzy :
Lee KH; Department of Dental Hygiene, College of Bio-Health Convergence, Dongseo University, Busan 47011, Korea.
Cha M; Department of Physiology, College of Medicine, Yonsei University, Seoul 03722, Korea.
Lee BH; Department of Physiology, College of Medicine, Yonsei University, Seoul 03722, Korea.; Brain Korea 21 PLUS Project for Medical Science, College of Medicine, Yonsei University, Seoul 03722, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 10; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Communication*
Neuroprotection*
Oxidative Stress*
Brain/*metabolism
Neuroglia/*metabolism
Neurons/*metabolism
Animals ; Antioxidants/metabolism ; Brain/pathology ; Humans ; Neuroglia/pathology ; Neurons/pathology
Czasopismo naukowe
Tytuł :
Contemporary Neuroprotection Strategies during Cardiac Surgery: State of the Art Review.
Autorzy :
Motshabi-Chakane P; Department of Anaesthesiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Mogane P; Department of Anaesthesiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Moutlana J; Department of Anaesthesiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Leballo-Mothibi G; Department of Anaesthesiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Dingezweni S; Department of Anaesthesiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Mpanya D; Department of Internal Medicine, Division of Cardiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
Tsabedze N; Department of Internal Medicine, Division of Cardiology, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg 2193, South Africa.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Dec 03; Vol. 18 (23). Date of Electronic Publication: 2021 Dec 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiac Surgical Procedures*/adverse effects
Neuroprotection*
Humans ; Morbidity
Czasopismo naukowe
Tytuł :
Association between Term Equivalent Brain Magnetic Resonance Imaging and 2-Year Outcomes in Extremely Preterm Infants: A Report from the Preterm Erythropoietin Neuroprotection Trial Cohort.
Autorzy :
Mayock DE; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA. Electronic address: .
Gogcu S; Division of Neonatology, Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC.
Puia-Dumitrescu M; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA.
Shaw DWW; Department of Radiology, University of Washington, Seattle, WA.
Wright JN; Department of Radiology, University of Washington, Seattle, WA.
Comstock BA; Department of Biostatistics, University of Washington, Seattle, WA.
Heagerty PJ; Department of Biostatistics, University of Washington, Seattle, WA.
Juul SE; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA.
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Corporate Authors :
Preterm Erythropoietin Neuroprotection (PENUT) Trial Consortium
Źródło :
The Journal of pediatrics [J Pediatr] 2021 Dec; Vol. 239, pp. 117-125.e6. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Neuroprotection*
Brain/*diagnostic imaging
Neurodevelopmental Disorders/*diagnostic imaging
Brain/pathology ; Child, Preschool ; Double-Blind Method ; Erythropoietin ; Female ; Humans ; Infant ; Infant, Extremely Premature ; Infant, Newborn ; Male ; Neurodevelopmental Disorders/pathology
Czasopismo naukowe
Tytuł :
Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections.
Autorzy :
Ahrends T; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. Electronic address: .
Aydin B; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Matheis F; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Classon CH; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Marchildon F; Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Furtado GC; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lira SA; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mucida D; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Nov 11; Vol. 184 (23), pp. 5715-5727.e12. Date of Electronic Publication: 2021 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotection*
Organ Specificity*
Enteric Nervous System/*microbiology
Enteric Nervous System/*parasitology
Infections/*microbiology
Infections/*parasitology
Neurons/*pathology
Yersinia pseudotuberculosis/*physiology
Animals ; Eosinophils/metabolism ; Hematopoietic Stem Cells/metabolism ; Immunity ; Infections/immunology ; Interleukin-13/metabolism ; Interleukin-4/metabolism ; Macrophages/metabolism ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Strongyloides/physiology ; Strongyloidiasis/genetics ; Strongyloidiasis/immunology ; Strongyloidiasis/parasitology ; Transcriptome/genetics ; Yersinia pseudotuberculosis Infections/genetics ; Yersinia pseudotuberculosis Infections/immunology ; Yersinia pseudotuberculosis Infections/microbiology
Czasopismo naukowe
Tytuł :
Retinal neuroprotection by controlled release of a VCP inhibitor from self-assembled nanoparticles.
Autorzy :
Sen M; Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.
Al-Amin M; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Kicková E; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Sadeghi A; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Puranen J; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Urtti A; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland; Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Caliceti P; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Salmaso S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Arango-Gonzalez B; Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany. Electronic address: .
Ueffing M; Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany. Electronic address: .
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Nov 10; Vol. 339, pp. 307-320. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanoparticles*
Neuroprotection*
Animals ; Delayed-Action Preparations ; Disease Models, Animal ; Rats ; Valosin Containing Protein
Czasopismo naukowe
Tytuł :
Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease.
Autorzy :
Ahuja M; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425.; Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425.
Ammal Kaidery N; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425.; Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425.
Attucks OC; vTv Therapeutics LLC, High Point, NC 27265.
McDade E; vTv Therapeutics LLC, High Point, NC 27265.
Hushpulian DM; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 109028, Russia.
Gaisin A; Integrated Molecular Structure Education and Research Center, Northwestern University, IL 60208.
Gaisina I; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago, IL 60612.
Ahn YH; Department of Chemistry, Wayne State University, Detroit, MI 48202.
Nikulin S; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 109028, Russia.
Poloznikov A; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 109028, Russia.
Gazaryan I; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 109028, Russia.; Department of Chemical Enzymology, M. V. Lomonosov Moscow State University, Moscow 119991, Russia.; Department of Chemistry and Physical Sciences, Pace University, Pleasantville, NY 10570.
Yamamoto M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.; Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Sendai 980-8573, Japan.
Matsumoto M; Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Igarashi K; Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Sharma SM; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
Thomas B; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425; .; Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425.; Department of Neuroscience, Medical University of South Carolina, Charleston, SC 29425.; Department of Drug Discovery, Medical University of South Carolina, Charleston, SC 29425.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Nov 09; Vol. 118 (45).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotection*
Basic-Leucine Zipper Transcription Factors/*metabolism
Parkinson Disease/*therapy
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Aged ; Aged, 80 and over ; Animals ; Antioxidant Response Elements ; Basic-Leucine Zipper Transcription Factors/antagonists & inhibitors ; Basic-Leucine Zipper Transcription Factors/genetics ; Case-Control Studies ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Female ; Humans ; Male ; Mice ; Mice, Knockout ; Parkinson Disease/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms.
Autorzy :
Shahsavani N; Department of Physiology and Pathophysiology, Regenerative Medicine Program, Spinal Cord Research Centre, Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Alizadeh A; Department of Physiology and Pathophysiology, Regenerative Medicine Program, Spinal Cord Research Centre, Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Kataria H; Department of Physiology and Pathophysiology, Regenerative Medicine Program, Spinal Cord Research Centre, Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Karimi-Abdolrezaee S; Department of Physiology and Pathophysiology, Regenerative Medicine Program, Spinal Cord Research Centre, Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: .
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Źródło :
Experimental neurology [Exp Neurol] 2021 Nov; Vol. 345, pp. 113817. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspases/*metabolism
Glutamic Acid/*toxicity
Neuregulin-1/*metabolism
Neuroprotection/*physiology
Spinal Cord Injuries/*metabolism
Spinal Cord Injuries/*prevention & control
Animals ; Cells, Cultured ; Female ; Neuregulin-1/administration & dosage ; Neuroprotection/drug effects ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor.
Autorzy :
Brahimi F; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Galan A; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Siegel S; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Szobota S; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Sarunic MV; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Foster AC; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.).
Saragovi HU; Lady Davis Institute-Jewish General Hospital (F.B., A.G., H.U.S.), Pharmacology and Therapeutics (H.U.S.), and Ophthalmology and Vision Science (H.U.S.), McGill University, Montreal, Quebec, Canada; Otonomy, Inc., San Diego, California (S.Si., S.Sz., A.C.F.); and School of Engineering Science, Simon Fraser University, British Columbia, Canada (M.V.S.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2021 Nov; Vol. 100 (5), pp. 491-501. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Nerve Growth Factors/*metabolism
Nerve Tissue Proteins/*metabolism
Neuroprotection/*physiology
Protein Engineering/*methods
Receptor, trkA/*metabolism
Receptors, Growth Factor/*metabolism
Animals ; Axotomy/adverse effects ; Diabetic Neuropathies/drug therapy ; Diabetic Neuropathies/genetics ; Diabetic Neuropathies/metabolism ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Nerve Growth Factors/administration & dosage ; Nerve Growth Factors/genetics ; Nerve Tissue Proteins/genetics ; Neuroprotection/drug effects ; Optic Nerve/drug effects ; Optic Nerve/metabolism ; Receptor, trkA/genetics ; Receptors, Growth Factor/genetics
Czasopismo naukowe
Tytuł :
Anti-inflammatory and neuroprotective properties of the corticosteroid fludrocortisone in retinal degeneration.
Autorzy :
Racic T; John Curtin School of Medical Research, The Australian National University, ACT, Australia.
Chang A; Sydney Retina Clinic & Day Surgery, Sydney, NSW, Australia; Save Sight Institute, The University of Sydney, NSW, Australia.
Fernando N; John Curtin School of Medical Research, The Australian National University, ACT, Australia.
Brandli A; Department of Anatomy and Physiology, The University of Melbourne, VIC, Australia.
Natoli R; John Curtin School of Medical Research, The Australian National University, ACT, Australia; ANU Medical School, The Australian National University, ACT, Australia.
Penfold P; John Curtin School of Medical Research, The Australian National University, ACT, Australia.
Provis JM; John Curtin School of Medical Research, The Australian National University, ACT, Australia; ANU Medical School, The Australian National University, ACT, Australia.
Rutar M; Department of Anatomy and Physiology, The University of Melbourne, VIC, Australia; Centre for Research in Therapeutic Solutions, Faculty of Science and Technology, University of Canberra, ACT, Australia. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2021 Nov; Vol. 212, pp. 108765. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotection*
Fludrocortisone/*pharmacology
Retinal Degeneration/*drug therapy
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Line ; Cytokines/metabolism ; Disease Models, Animal ; Humans ; Mice ; Mice, Inbred C57BL ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology
Czasopismo naukowe
Tytuł :
Sildenafil-Mediated Neuroprotection from Adult to Neonatal Brain Injury: Evidence, Mechanisms, and Future Translation.
Autorzy :
Zinni M; Inserm UMR1141 NeuroDiderot, Université de Paris, 75019 Paris, France.
Pansiot J; Inserm UMR1141 NeuroDiderot, Université de Paris, 75019 Paris, France.
Léger PL; Pediatric and Neonatal Intensive Care Unit, Armand-Trousseau University Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne University, 75019 Paris, France.
El Kamouh M; Inserm UMR1141 NeuroDiderot, Université de Paris, 75019 Paris, France.; Laboratoire de Physiologie et Génomique des Poissons-INRAE, 35700 Rennes, France.
Baud O; Laboratory of Child Growth and Development, University of Geneva, 1211 Geneva, Switzerland.; Division of Neonatology and Pediatric Intensive Care, Children's University Hospital of Geneva, 1211 Geneva, Switzerland.
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Źródło :
Cells [Cells] 2021 Oct 15; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neuroprotection*/drug effects
Translational Research, Biomedical*
Brain Injuries/*drug therapy
Sildenafil Citrate/*therapeutic use
Adult ; Humans ; Infant, Newborn ; Nitric Oxide/metabolism ; Sex Characteristics ; Sildenafil Citrate/pharmacology
Czasopismo naukowe
Tytuł :
Effects of lactate and carbon monoxide interactions on neuroprotection and neuropreservation.
Autorzy :
Mahan VL; Department of Surgery and Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA.
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Źródło :
Medical gas research [Med Gas Res] 2021 Oct-Dec; Vol. 11 (4), pp. 158-173.
Typ publikacji :
Journal Article
MeSH Terms :
Lactic Acid*
Neuroprotection*
Astrocytes ; Carbon Monoxide ; Neurons
Czasopismo naukowe
Tytuł :
Neuronal CD200 Signaling Is Protective in the Acute Phase of Ischemic Stroke.
Autorzy :
Al Mamun A; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Ngwa C; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Qi S; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Honarpisheh P; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Datar S; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Sharmeen R; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Xu Y; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
McCullough LD; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
Liu F; Department of Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.
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Źródło :
Stroke [Stroke] 2021 Oct; Vol. 52 (10), pp. 3362-3373. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neuroprotection*
Antigens, CD/*analysis
Ischemic Stroke/*prevention & control
Neurons/*physiology
Stroke/*prevention & control
Animals ; Antigens, CD/genetics ; Apoptosis ; Cytokines/metabolism ; Immunity, Cellular ; Infarction, Middle Cerebral Artery/complications ; Inflammation/etiology ; Inflammation/prevention & control ; Ischemic Stroke/psychology ; Macrophage Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/immunology ; Neutrophil Infiltration ; Signal Transduction ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity.
Autorzy :
Menchinskaya E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Chingizova E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Pislyagin E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Likhatskaya G; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Sabutski Y; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Pelageev D; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.; School of Natural Sciences, Far Eastern Federal University, Ajax Bay, Russky Island, 690922 Vladivostok, Russia.
Polonik S; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Aminin D; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 14; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Neuroprotection*/drug effects
Naphthoquinones/*pharmacology
Neuroprotective Agents/*pharmacology
Neurotoxins/*toxicity
Oxidopamine/*toxicity
Paraquat/*toxicity
Animals ; Biphenyl Compounds/chemistry ; Cell Cycle/drug effects ; Cell Line ; Cell Survival/drug effects ; Free Radical Scavengers/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Nitric Oxide/biosynthesis ; Picrates/chemistry ; Quantitative Structure-Activity Relationship ; Reactive Oxygen Species/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Erythropoietin and derivatives: Potential beneficial effects on the brain.
Autorzy :
Vittori DC; Department of Biological Chemistry, National Scientific and Technical Research Council, Institute of Biological Chemistry (IQUIBICEN), School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.
Chamorro ME; Department of Biological Chemistry, National Scientific and Technical Research Council, Institute of Biological Chemistry (IQUIBICEN), School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.
Hernández YV; Department of Biological Chemistry, National Scientific and Technical Research Council, Institute of Biological Chemistry (IQUIBICEN), School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.
Maltaneri RE; Department of Biological Chemistry, National Scientific and Technical Research Council, Institute of Biological Chemistry (IQUIBICEN), School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.
Nesse AB; Department of Biological Chemistry, National Scientific and Technical Research Council, Institute of Biological Chemistry (IQUIBICEN), School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Sep; Vol. 158 (5), pp. 1032-1057. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Brain/*metabolism
Erythropoietin/*metabolism
Neurodegenerative Diseases/*metabolism
Neuroprotection/*physiology
Receptors, Erythropoietin/*metabolism
Animals ; Brain/drug effects ; Erythropoietin/administration & dosage ; Humans ; Neurodegenerative Diseases/therapy ; Neuroprotection/drug effects
Czasopismo naukowe
Tytuł :
Head Mild Hypothermia Exerts a Neuroprotective Role in Ischemia-Reperfusion Injury by Maintaining Glial Glutamate Transporter 1.
Autorzy :
Ma D; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
An Q; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Zhang Z; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Bian Q; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Li Y; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Li Y; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Zhang S; Department of Anesthesiology, Second Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
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Źródło :
Therapeutic hypothermia and temperature management [Ther Hypothermia Temp Manag] 2021 Sep; Vol. 11 (3), pp. 155-163. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia*/therapy
Hypothermia, Induced*
Neuroprotection*
Reperfusion Injury*/prevention & control
Excitatory Amino Acid Transporter 2/*metabolism
Animals ; Rats
Czasopismo naukowe
Tytuł :
Paeoniflorin: A neuroprotective monoterpenoid glycoside with promising anti-depressive properties.
Autorzy :
Wang XL; Department of Anatomy, School of Chinese Medicine, Beijing University of Chinese Medicine, Sunshine Southern Avenue, Fang-Shan District, Beijing 102488, China.
Feng ST; Department of Anatomy, School of Chinese Medicine, Beijing University of Chinese Medicine, Sunshine Southern Avenue, Fang-Shan District, Beijing 102488, China.
Wang YT; Department of Anatomy, School of Chinese Medicine, Beijing University of Chinese Medicine, Sunshine Southern Avenue, Fang-Shan District, Beijing 102488, China.
Chen NH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Xian-Nong-Tan Street, Xi-Cheng District, Beijing 100050, China.
Wang ZZ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Xian-Nong-Tan Street, Xi-Cheng District, Beijing 100050, China. Electronic address: .
Zhang Y; Department of Anatomy, School of Chinese Medicine, Beijing University of Chinese Medicine, Sunshine Southern Avenue, Fang-Shan District, Beijing 102488, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Sep; Vol. 90, pp. 153669. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuroprotection*
Antidepressive Agents/*pharmacology
Glucosides/*pharmacology
Monoterpenes/*pharmacology
Humans ; Hypothalamo-Hypophyseal System ; Neurotransmitter Agents ; Paeonia/chemistry ; Pituitary-Adrenal System
Czasopismo naukowe
Tytuł :
Inhibition of the HIF-1α/BNIP3 pathway has a retinal neuroprotective effect.
Autorzy :
Kunimi H; Laboratory of Photobiology, Keio University School of Medicine, Shinanomachi, Japan.; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
Lee D; Laboratory of Photobiology, Keio University School of Medicine, Shinanomachi, Japan.; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
Ibuki M; Laboratory of Photobiology, Keio University School of Medicine, Shinanomachi, Japan.; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
Katada Y; Laboratory of Photobiology, Keio University School of Medicine, Shinanomachi, Japan.; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
Negishi K; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
Tsubota K; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.; Tsubota Laboratory, Inc., Tokyo, Japan.
Kurihara T; Laboratory of Photobiology, Keio University School of Medicine, Shinanomachi, Japan.; Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Aug; Vol. 35 (8), pp. e21829.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Neuroprotection*
Retina*/metabolism
Retina*/pathology
Hypoxia-Inducible Factor 1, alpha Subunit/*physiology
Membrane Proteins/*physiology
Mitochondrial Proteins/*physiology
Retinal Degeneration/*metabolism
Animals ; Cell Line ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł :
First Episode Psychosis and Schizophrenia Are Systemic Neuro-Immune Disorders Triggered by a Biotic Stimulus in Individuals with Reduced Immune Regulation and Neuroprotection.
Autorzy :
Maes M; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.; Department of Psychiatry, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.; IMPACT Strategic Research Center, Deakin University, Geelong 3220, Australia.
Plaimas K; Advanced Virtual and Intelligent Computing (AVIC) Center, Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Suratanee A; Department of Mathematics, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok, Bangkok 10800, Thailand.
Noto C; GAPi (Early Psychosis Group), Universidade Federal de São Paulo (UNIFESP), São Paulo 04021-001, Brazil.; Schizophrenia Program (PROESQ), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo 04021-001, Brazil.
Kanchanatawan B; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
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Źródło :
Cells [Cells] 2021 Oct 28; Vol. 10 (11). Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotection*/genetics
Psychotic Disorders/*immunology
Schizophrenia/*immunology
Down-Regulation/genetics ; Gene Ontology ; Humans ; Molecular Sequence Annotation ; Protein Interaction Maps/genetics ; Psychotic Disorders/genetics ; Schizophrenia/genetics ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
The GABA B receptor mediates neuroprotection by coupling to G 13 .
Autorzy :
Wang Y; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Gai S; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Zhang W; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Huang X; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Ma S; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Huo Y; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Wu Y; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Tu H; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Pin JP; Institut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.
Rondard P; Institut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.
Xu C; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.
Liu J; Cellular Signaling laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, School of Life Science and Technology, Huazhong University of Science and Technology, 430074 Wuhan, China.; Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, 510005 Guangzhou, China.
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Źródło :
Science signaling [Sci Signal] 2021 Oct 19; Vol. 14 (705), pp. eaaz4112. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroprotection*
Receptors, GABA-B*
gamma-Aminobutyric Acid
Czasopismo naukowe
Tytuł :
Induction of ischemic tolerance by remote perconditioning or postconditioning as neuroprotective strategy for spinal cord motor neurons.
Autorzy :
Danková M; Comenius University in Bratislava, Faculty of Medicine, Institute of Histology and Embryology, Sasinkova 4, 811 04 Bratislava, Slovak Republic.
Domoráková I; Pavol Jozef Šafárik University, Faculty of Medicine, Department of Histology and Embryology, Šrobárova 2, 040 01 Košice, Slovak Republic.
Fagová Z; Pavol Jozef Šafárik University, Faculty of Medicine, Department of Histology and Embryology, Šrobárova 2, 040 01 Košice, Slovak Republic.
Stebnický M; Pavol Jozef Šafárik University, Faculty of Medicine, Department of Histology and Embryology, Šrobárova 2, 040 01 Košice, Slovak Republic; Pavol Jozef Šafárik University, Faculty of Medicine, 2nd Department of Surgery and L. Pasteur University Hospital, Rastislavova 43, 040 01 Košice, Slovak Republic. Electronic address: .
Mechírová E; Pavol Jozef Šafárik University, Faculty of Medicine, Department of Histology and Embryology, Šrobárova 2, 040 01 Košice, Slovak Republic.
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Źródło :
Life sciences [Life Sci] 2021 Oct 15; Vol. 283, pp. 119789. Date of Electronic Publication: 2021 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Ischemic Preconditioning*
Neuroprotection*
Motor Neurons/*metabolism
Spinal Cord/*metabolism
Spinal Cord Ischemia/*metabolism
Spinal Cord Ischemia/*prevention & control
Animals ; Male ; Motor Neurons/pathology ; Rabbits ; Spinal Cord/pathology ; Spinal Cord Ischemia/pathology
Czasopismo naukowe

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