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Wyszukujesz frazę ""Neuroprotective Agents"" wg kryterium: Temat


Tytuł :
Donepezil in the treatment of ischemic stroke: Review and future perspective.
Autorzy :
Barfejani AH; Department of Pharmacy, Mayo Clinic, Rochester, MN, 55902, USA; School of Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. Electronic address: .
Jafarvand M; Department of Surgery, Harlem Hospital Center, affiliated to Columbia University, NYC, NY 10037, USA.
Seyedsaadat SM; Department of Radiology, Mayo Clinic, Jacksonville, FL 32224, USA.
Rasekhi RT; Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118575. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Donepezil/*therapeutic use
Ischemic Stroke/*drug therapy
Neuroprotective Agents/*therapeutic use
Animals ; Cholinesterase Inhibitors/adverse effects ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Donepezil/adverse effects ; Donepezil/pharmacology ; Humans ; Ischemic Stroke/physiopathology ; Neuroprotective Agents/adverse effects ; Neuroprotective Agents/pharmacology ; Recovery of Function
Czasopismo naukowe
Tytuł :
Design, synthesis, structural analysis and biochemical studies of stapled AIF(370-394) analogues as ligand of CypA.
Autorzy :
Monti A; Istituto di Biostrutture e Bioimmagini-CNR; Via Mezzocannone, 16, 80134 Napoli, Italy; DISTABIF, Università degli Studi della Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, CE, Italy.
Sturlese M; Molecular Modeling Section, Dipartimento di Scienze del Farmaco, Università di Padova, via F. Marzolo 5, 35131 Padova, Italy.
Caporale A; Istituto di Biostrutture e Bioimmagini-CNR; Via Mezzocannone, 16, 80134 Napoli, Italy.
Roger JA; Molecular Modeling Section, Dipartimento di Scienze del Farmaco, Università di Padova, via F. Marzolo 5, 35131 Padova, Italy.
Mascanzoni F; Istituto di Biostrutture e Bioimmagini-CNR; Via Mezzocannone, 16, 80134 Napoli, Italy.
Ruvo M; Istituto di Biostrutture e Bioimmagini-CNR; Via Mezzocannone, 16, 80134 Napoli, Italy.
Doti N; Istituto di Biostrutture e Bioimmagini-CNR; Via Mezzocannone, 16, 80134 Napoli, Italy. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2020 Dec; Vol. 1864 (12), pp. 129717. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis Inducing Factor/*metabolism
Cyclophilin A/*metabolism
Neuroprotective Agents/*chemistry
Neuroprotective Agents/*pharmacology
Peptides/*chemistry
Peptides/*pharmacology
Apoptosis Inducing Factor/chemistry ; Drug Design ; Humans ; Ligands ; Molecular Docking Simulation ; Neuroprotective Agents/chemical synthesis ; Peptides/chemical synthesis
Czasopismo naukowe
Tytuł :
The seed of Litchi chinensis fraction ameliorates hippocampal neuronal injury in an Aβ 25-35 -induced Alzheimer's disease rat model via the AKT/GSK-3β pathway.
Autorzy :
Sun Y; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Wu A; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
Li X; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Department of Anatomy and Histology and Embryology, Chengdu Medical College, Chengdu, China.
Qin D; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
Jin B; Department of Human Anatomy, Chengdu Medical Collage, Chengdu, China.
Liu J; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
Tang Y; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
Wu J; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
Yu C; Institute of Cardiovascular Research, The Key Laboratory of Medical Electrophysiology, Southwest Medical University, Luzhou, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 35-43.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Litchi/*chemistry
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Alzheimer Disease/physiopathology ; Amyloid beta-Peptides/toxicity ; Animals ; Disease Models, Animal ; Donepezil/pharmacology ; Dose-Response Relationship, Drug ; Glycogen Synthase Kinase 3 beta/metabolism ; Hippocampus/drug effects ; Hippocampus/pathology ; Male ; Maze Learning/drug effects ; Neurons/drug effects ; Neurons/pathology ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/isolation & purification ; Peptide Fragments/toxicity ; Plant Extracts/administration & dosage ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Seeds
Czasopismo naukowe
Tytuł :
Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.
Autorzy :
Fancellu G; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.; Department of Earth Sciences, University of Pisa, Pisa, Italy.
Chand K; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
Tomás D; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
Orlandini E; Department of Earth Sciences, University of Pisa, Pisa, Italy.
Piemontese L; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', Bari, Italy.
Silva DF; CNC-Center for Neuroscience and Cell Biology, Universidade de Coimbra, Coimbra, Portugal.
Cardoso SM; CNC-Center for Neuroscience and Cell Biology, Universidade de Coimbra, Coimbra, Portugal.; Institute of Molecular and Cell Biology, Faculty of Medicine, Universidade de Coimbra, Coimbra, Portugal.
Chaves S; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
Santos MA; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 211-226.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Benzofurans/*pharmacology
Cholinesterase Inhibitors/*pharmacology
Neuroprotective Agents/*pharmacology
Tacrine/*pharmacology
Acetylcholinesterase/metabolism ; Alzheimer Disease/metabolism ; Animals ; Benzofurans/chemistry ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Electrophorus ; Humans ; Models, Molecular ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Structure-Activity Relationship ; Tacrine/chemistry
Czasopismo naukowe
Tytuł :
Neuroprotective Effects of Curcumin-Loaded Emulsomes in a Laser Axotomy-Induced CNS Injury Model.
Autorzy :
Yilmaz EN; Regenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Beykoz, Istanbul, Turkey.; Graduate School of Engineering and Natural Sciences, Istanbul Medipol University, Beykoz, Istanbul, Turkey.
Bay S; Regenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Beykoz, Istanbul, Turkey.
Ozturk G; Regenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Beykoz, Istanbul, Turkey.; Department of Physiology, International School of Medicine, Istanbul Medipol University, Beykoz, Istanbul, Turkey.
Ucisik MH; Regenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Beykoz, Istanbul, Turkey.; Department of Biomedical Engineering, School of Engineering and Natural Sciences, Istanbul Medipol University, Beykoz, Istanbul, Turkey.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2020 Nov 20; Vol. 15, pp. 9211-9229. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Curcumin/*pharmacology
Drug Delivery Systems/*methods
Emulsions/*chemistry
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Animals ; Antioxidants/pharmacology ; Axotomy ; Biomarkers/metabolism ; Cell Survival/drug effects ; Cells, Cultured ; Central Nervous System/injuries ; Curcumin/administration & dosage ; Curcumin/pharmacokinetics ; Emulsions/administration & dosage ; Hippocampus/cytology ; Hippocampus/drug effects ; Lasers ; Mice, Inbred BALB C ; Nanostructures/administration & dosage ; Nanostructures/chemistry ; Neurons/cytology ; Neurons/metabolism ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/pharmacokinetics ; Proto-Oncogene Proteins c-bcl-2/metabolism
Czasopismo naukowe
Tytuł :
From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3- n -Butylphthalide.
Autorzy :
Marco-Contelles J; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry, CSIC, Juan de la Cierva, 3, 28006-Madrid, Spain.
Zhang Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China.; Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, PR China.; Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, PR China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Nov 12; Vol. 63 (21), pp. 12485-12510. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apium/*chemistry
Benzofurans/*chemistry
Brain Ischemia/*drug therapy
Neuroprotective Agents/*therapeutic use
Animals ; Apium/metabolism ; Asthma/drug therapy ; Asthma/pathology ; Benzofurans/chemical synthesis ; Benzofurans/therapeutic use ; Brain Ischemia/pathology ; Humans ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Seeds/chemistry ; Seeds/metabolism ; Stereoisomerism ; Stroke/drug therapy ; Stroke/pathology
Czasopismo naukowe
Tytuł :
A new oleanane type pentacyclic triterpenoid saponin from the husks of xanthoceras sorbifolium bunge and its neuroprotection on PC12 cells injury induced by Aβ 25-35 .
Autorzy :
Ding K; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Guo S; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Rong W; School of Traditional Chinese Materia Medica, Shenyang Parmaceutical University, Shenyang, China.
Li Q; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Liu R; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Xu H; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Yin Y; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
Bi K; School of Pharmacy, Shenyang Parmaceutical University, Shenyang, China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Nov; Vol. 34 (22), pp. 3212-3218. Date of Electronic Publication: 2019 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid beta-Peptides/*toxicity
Neuroprotective Agents/*chemistry
Neuroprotective Agents/*pharmacology
Peptide Fragments/*toxicity
Sapindaceae/*chemistry
Animals ; Cell Survival/drug effects ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Neuroprotective Agents/isolation & purification ; Nuts/chemistry ; Oleanolic Acid/analogs & derivatives ; Oleanolic Acid/chemistry ; PC12 Cells/drug effects ; Rats ; Saponins/chemistry ; Spectrometry, Mass, Electrospray Ionization ; Triterpenes/chemistry ; Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
Isolation and characterization of components responsible for neuroprotective effects of Allium cepa outer scale extract against ischemia reperfusion induced cerebral injury in mice.
Autorzy :
Singh V; Department of Pharmaceutical Sciences and Drug Research, Punjabi University Patiala, India.; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Shri R; Department of Pharmaceutical Sciences and Drug Research, Punjabi University Patiala, India.
Krishan P; Department of Pharmaceutical Sciences and Drug Research, Punjabi University Patiala, India.
Singh IP; Natural Products Research Laboratory, Department of Natural Products, National Institute of Pharmaceutical Education and Research, SAS Nagar, India.
Shah P; Natural Products Research Laboratory, Department of Natural Products, National Institute of Pharmaceutical Education and Research, SAS Nagar, India.
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Źródło :
Journal of food science [J Food Sci] 2020 Nov; Vol. 85 (11), pp. 4009-4017. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents/*administration & dosage
Neuroprotective Agents/*chemistry
Onions/*chemistry
Plant Extracts/*administration & dosage
Plant Extracts/*chemistry
Reperfusion Injury/*drug therapy
Animals ; Antioxidants/administration & dosage ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Brain/drug effects ; Brain/metabolism ; Female ; Humans ; Male ; Memory/drug effects ; Mice ; Neuroprotective Agents/isolation & purification ; Oxidative Stress/drug effects ; Plant Extracts/isolation & purification ; Plant Leaves/chemistry ; Reperfusion Injury/metabolism ; Reperfusion Injury/psychology
Czasopismo naukowe
Tytuł :
[The neuroprotective role of EAAC1 in hippocampal injury following ischemia-reperfusion].
Autorzy :
Higashi Y; Department of Pharmacology, Kochi Medical School, Kochi University.
Aratake T; Department of Pharmacology, Kochi Medical School, Kochi University.
Shimizu S; Department of Pharmacology, Kochi Medical School, Kochi University.
Shimizu T; Department of Pharmacology, Kochi Medical School, Kochi University.
Saito M; Department of Pharmacology, Kochi Medical School, Kochi University.
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Źródło :
Nihon yakurigaku zasshi. Folia pharmacologica Japonica [Nihon Yakurigaku Zasshi] 2021; Vol. 156 (1), pp. 21-25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuroprotective Agents*/pharmacology
Reperfusion Injury*
Animals ; Excitatory Amino Acid Transporter 3/metabolism ; Glutathione/metabolism ; Glutathione/pharmacology ; Hippocampus/metabolism ; Ischemia ; Oxidative Stress ; Reperfusion
Czasopismo naukowe
Tytuł :
[Anti-oxidants in astrocytes as target of neuroprotection for Parkinson's disease].
Autorzy :
Asanuma M; Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentist and Pharmaceutical Sciences.
Miyazaki I; Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentist and Pharmaceutical Sciences.
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Źródło :
Nihon yakurigaku zasshi. Folia pharmacologica Japonica [Nihon Yakurigaku Zasshi] 2021; Vol. 156 (1), pp. 14-20.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents*/pharmacology
Parkinson Disease*/drug therapy
Antioxidants/pharmacology ; Astrocytes ; Glutathione ; Humans ; Neuroprotection
Czasopismo naukowe
Tytuł :
Protection induced by estradiol benzoate in the MPP rat model of Parkinson's disease is associated with the regulation of the inflammatory cytokine profile in the nigro striatum.
Autorzy :
Aguirre-Vidal Y; Laboratorio de Neuroprotección, Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico.
Morales-Montor J; Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico. Electronic address: .
Gómez de León CT; Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Ostoa-Saloma P; Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Díaz-Zaragoza M; Laboratorio de Sistemas Biológicos, Departamento de Ciencias de la Salud, Centro Universitario de los Valles, Universidad de Guadalajara, C.P. 46600 Ameca, Jalisco, Mexico.
Montes S; Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía, 'Dr. Manuel Velasco Suárez', Ciudad de México, Mexico.
Arteaga-Silva M; Departamento de Biología de la Reproducción, Universidad Autónoma Metropolitana-Iztapalapa, Ciudad de México, Mexico.
Monroy-Noyola A; Laboratorio de Neuroprotección, Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico. Electronic address: .
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2020 Dec 15; Vol. 349, pp. 577426. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Corpus Striatum/*metabolism
Cytokines/*metabolism
Estradiol/*analogs & derivatives
Neuroprotective Agents/*therapeutic use
Parkinsonian Disorders/*metabolism
Substantia Nigra/*metabolism
1-Methyl-4-phenylpyridinium/toxicity ; Animals ; Corpus Striatum/drug effects ; Cytokines/antagonists & inhibitors ; Estradiol/pharmacology ; Estradiol/therapeutic use ; Male ; Neuroprotective Agents/pharmacology ; Parkinsonian Disorders/chemically induced ; Parkinsonian Disorders/prevention & control ; Random Allocation ; Rats ; Rats, Wistar ; Substantia Nigra/drug effects
Czasopismo naukowe
Tytuł :
Can selective serotonin reuptake inhibitors have a neuroprotective effect during COVID-19?
Autorzy :
Costa LHA; Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, 14040-904, Brazil.
Santos BM; Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, 14040-904, Brazil.
Branco LGS; Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, 14040-904, Brazil. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2020 Dec 15; Vol. 889, pp. 173629. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*drug therapy
Inflammation/*drug therapy
Nervous System Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Serotonin Uptake Inhibitors/*therapeutic use
Animals ; COVID-19/complications ; Humans ; Inflammation/complications ; Nervous System Diseases/complications ; Neuroprotective Agents/pharmacology ; Pandemics ; SARS-CoV-2 ; Serotonin Uptake Inhibitors/pharmacology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Prevention of oxaliplatin-related neurotoxicity by ω-3 PUFAs: A double-blind randomized study of patients receiving oxaliplatin combined with capecitabine for colon cancer.
Autorzy :
Zhang X; Zhejiang Chinese Medical University.
Chen H; Zhejiang Chinese Medical University.
Lu Y; Department of Nutrition.
Xu C; Department of Integrated Traditional Chinese and Western Medicine, the Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital).
Yao W; Zhejiang Chinese Medical University.
Xu L; Zhejiang Chinese Medical University.
Zhang R; Zhejiang Chinese Medical University.
Zhang L; The First Affiliated Hospital of Zhejiang Chinese Medical University.
Yao Q; Department of Integrated Traditional Chinese and Western Medicine, the Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital).; Key Laboratory of Traditional Chinese Medicine Oncology, the Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 11; Vol. 99 (50), pp. e23564.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Capecitabine/*therapeutic use
Colonic Neoplasms/*drug therapy
Fatty Acids, Omega-3/*therapeutic use
Neuroprotective Agents/*therapeutic use
Neurotoxicity Syndromes/*prevention & control
Oxaliplatin/*toxicity
Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/toxicity ; Capecitabine/administration & dosage ; Double-Blind Method ; Drug Administration Schedule ; Fatty Acids, Omega-3/administration & dosage ; Female ; Humans ; Male ; Middle Aged ; Neuroprotective Agents/administration & dosage ; Neurotoxicity Syndromes/etiology ; Oxaliplatin/administration & dosage ; Oxaliplatin/therapeutic use ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/prevention & control ; Quality of Life ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł :
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review.
Autorzy :
Zhang S; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao.
Zhu Q; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao.
Chen JY; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao.
OuYang D; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao.
Lu JH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Dec; Vol. 79, pp. 153316. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Alzheimer Disease/*drug therapy
Catechin/*analogs & derivatives
Neuroprotective Agents/*pharmacology
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyloid Precursor Protein Secretases/metabolism ; Animals ; Antioxidants/pharmacology ; Blood-Brain Barrier/drug effects ; Catechin/pharmacokinetics ; Catechin/pharmacology ; Cognition/drug effects ; Disease Models, Animal ; Humans ; Neuroprotective Agents/pharmacokinetics ; Phosphorylation/drug effects
Czasopismo naukowe
Tytuł :
Enhanced neurogenesis is involved in neuroprotection provided by rottlerin against trimethyltin-induced delayed apoptotic neuronal damage.
Autorzy :
Hwang Y; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon 24341, Republic of Korea.
Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon 24341, Republic of Korea. Electronic address: .
Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon 24341, Republic of Korea. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 01; Vol. 262, pp. 118494. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Acetophenones/*pharmacology
Apoptosis/*drug effects
Benzopyrans/*pharmacology
Neurogenesis/*drug effects
Neuroprotective Agents/*pharmacology
Acetophenones/administration & dosage ; Animals ; Behavior, Animal/drug effects ; Benzopyrans/administration & dosage ; Dentate Gyrus/drug effects ; Dentate Gyrus/pathology ; Extracellular Signal-Regulated MAP Kinases/genetics ; Male ; Memory Disorders/prevention & control ; Mice ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/pathology ; Neuroprotective Agents/administration & dosage ; Seizures/prevention & control ; Time Factors ; Trimethyltin Compounds/toxicity ; Up-Regulation
Czasopismo naukowe
Tytuł :
XingNaoJing injection ameliorates cerebral ischaemia/reperfusion injury via SIRT1-mediated inflammatory response inhibition.
Autorzy :
Zhang YM; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Qu XY; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Tao LN; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Zhai JH; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Gao H; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Song YQ; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Zhang SX; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 16-24.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal/*pharmacology
Inflammation/*drug therapy
Neuroprotective Agents/*pharmacology
Reperfusion Injury/*drug therapy
Animals ; Brain/cytology ; Brain Ischemia/drug therapy ; Carbazoles/pharmacology ; Disease Models, Animal ; Drugs, Chinese Herbal/administration & dosage ; Endothelial Cells/drug effects ; Endothelial Cells/pathology ; Humans ; Infarction, Middle Cerebral Artery ; Inflammation/pathology ; Male ; Neuroprotective Agents/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/pathology ; Sirtuin 1/antagonists & inhibitors ; Sirtuin 1/metabolism
Czasopismo naukowe
Tytuł :
Equol, a Blood-Brain Barrier Permeable Gut Microbial Metabolite of Dietary Isoflavone Daidzein, Exhibits Neuroprotective Effects against Neurotoxins Induced Toxicity in Human Neuroblastoma SH-SY5Y Cells and Caenorhabditis elegans.
Autorzy :
Johnson SL; Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, 02881, USA.; George and Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, 02881, USA.
Park HY; Edison Biotechnology Institute, Ohio University, Athens, OH, 45701, USA.; School of Applied Health Sciences and Wellness, Ohio University, Athens, OH, 45701, USA.
Vattem DA; Edison Biotechnology Institute, Ohio University, Athens, OH, 45701, USA.; School of Applied Health Sciences and Wellness, Ohio University, Athens, OH, 45701, USA.
Grammas P; George and Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, 02881, USA.
Ma H; Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, 02881, USA. .; George and Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, 02881, USA. .
Seeram NP; Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, 02881, USA. .; George and Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, 02881, USA. .
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Źródło :
Plant foods for human nutrition (Dordrecht, Netherlands) [Plant Foods Hum Nutr] 2020 Dec; Vol. 75 (4), pp. 512-517.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*
Isoflavones*/pharmacology
Neuroblastoma*
Neuroprotective Agents*/pharmacology
Animals ; Apoptosis ; Blood-Brain Barrier ; Caenorhabditis elegans ; Cell Line, Tumor ; Equol/pharmacology ; Humans ; Mice ; Neurotoxins/toxicity
Czasopismo naukowe
Tytuł :
How the CORAL software can be used to select compounds for efficient treatment of neurodegenerative diseases?
Autorzy :
Toropova AP; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy. Electronic address: .
Toropov AA; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy. Electronic address: .
Leszczynska D; Interdisciplinary Nanotoxicity Center, Department of Civil and Environmental Engineering, Jackson State University, 1325 Lynch Street, Jackson, MS 39217-0510, USA. Electronic address: .
Leszczynski J; Interdisciplinary Nanotoxicity Center, Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, 1400 J. R. Lynch Street, P.O. Box 17910, Jackson, MS 39217, USA. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Dec 01; Vol. 408, pp. 115276. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Molecular*
Software*
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*antagonists & inhibitors
Neurodegenerative Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Receptor, trkA/*antagonists & inhibitors
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Monte Carlo Method ; Neuroprotective Agents/chemistry ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Methylene blue promotes survival and GAP-43 expression of retinal ganglion cells after optic nerve transection.
Autorzy :
Fung JCL; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address: .
Cho EYP; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
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Źródło :
Life sciences [Life Sci] 2020 Dec 01; Vol. 262, pp. 118462. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
GAP-43 Protein/*genetics
Methylene Blue/*pharmacology
Neuroprotective Agents/*pharmacology
Optic Nerve Injuries/*drug therapy
Retinal Ganglion Cells/*drug effects
Animals ; Axons ; Cell Survival/drug effects ; Cricetinae ; Disease Models, Animal ; Female ; Intravitreal Injections ; Methylene Blue/administration & dosage ; Nerve Regeneration/drug effects ; Neuroprotective Agents/administration & dosage ; Optic Nerve/drug effects ; Optic Nerve/pathology ; Optic Nerve Injuries/physiopathology ; Retinal Ganglion Cells/cytology ; Time Factors
Czasopismo naukowe
Tytuł :
The protective effect of 5-O-methylvisammioside on LPS-induced depression in mice by inhibiting the over activation of BV-2 microglia through Nf-κB/IκB-α pathway.
Autorzy :
Sun X; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Zhang T; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Zhao Y; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China. Electronic address: .
Cai E; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Zhu H; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Liu S; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China; National & Local Joint Engineering Research Center for Ginseng Breeding and Application, Jilin Agricultural University, Changchun, Jilin, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Dec; Vol. 79, pp. 153348. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Antidepressive Agents/*pharmacology
Depression/*drug therapy
Drugs, Chinese Herbal/*pharmacology
Microglia/*drug effects
Neuroprotective Agents/*pharmacology
Animals ; Antidepressive Agents/chemistry ; Behavior, Animal/drug effects ; Brain/drug effects ; Brain/metabolism ; Cell Line ; Cytokines/blood ; Depression/chemically induced ; Depression/metabolism ; Lipopolysaccharides/toxicity ; Male ; Mice, Inbred ICR ; Microglia/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; NF-kappa B/metabolism ; Neuroprotective Agents/chemistry ; Nitric Oxide/metabolism ; Phosphorylation/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe

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