Temat: "Neuroprotective Agents" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.
Autorzy:: Matsumura N; Department of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan.
Aoyama K; Department of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 22; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Alzheimer Disease*/drug therapy
Alzheimer Disease*/prevention & control
Glutathione*/metabolism
Neuroprotection*
Neuroprotective Agents*/chemistry
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Parkinson Disease*/drug therapy
Parkinson Disease*/prevention & control
Purines*/chemistry
Purines*/pharmacology
Purines*/therapeutic use
Humans ; Adenosine A2 Receptor Antagonists/chemistry ; Adenosine A2 Receptor Antagonists/pharmacology ; Adenosine A2 Receptor Antagonists/therapeutic use ; Brain/metabolism ; Cysteine/metabolism ; Excitatory Amino Acid Transporter 3/metabolism ; Receptor, Adenosine A2A ; Theophylline/chemistry ; Theophylline/pharmacology ; Theophylline/therapeutic use ; Uric Acid/blood ; Caffeine/chemistry ; Caffeine/pharmacology ; Caffeine/therapeutic use

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Skocz do pozycji: 2.

Tytuł:: Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection.
Autorzy:: Canovai A; Division of Eye and Vision, Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.; Department of Biology, University of Pisa, Pisa, Italy.
Tribble JR; Division of Eye and Vision, Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
Jöe M; Division of Eye and Vision, Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
Westerlund DY; Division of Eye and Vision, Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
Amato R; Department of Biology, University of Pisa, Pisa, Italy.
Trounce IA; Department of Surgery, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Ophthalmology, University of Melbourne, Melbourne, VIC, Australia.
Dal Monte M; Department of Biology, University of Pisa, Pisa, Italy.
Williams PA; Division of Eye and Vision, Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden. .; Pokaż więcej
Źródło:: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Sep 08; Vol. 11 (1), pp. 146. Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neuroprotection*
Neuroprotective Agents*/pharmacology
Retinal Ganglion Cells ; PQQ Cofactor/pharmacology ; Adenosine Triphosphate

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Skocz do pozycji: 3.

Tytuł:: The Potential Benefits of Quercetin for Brain Health: A Review of Anti-Inflammatory and Neuroprotective Mechanisms.
Autorzy:: Chiang MC; Department of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Tsai TY; Department of Food Science, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Wang CJ; Department of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City 242062, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 28; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Quercetin*/pharmacology
Quercetin*/therapeutic use
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Brain Diseases*/chemically induced
Brain Diseases*/prevention & control
Neuroprotection*
Neuroinflammatory Diseases/chemically induced ; Neuroinflammatory Diseases/prevention & control ; Neurodegenerative Diseases/chemically induced ; Neurodegenerative Diseases/prevention & control ; Particulate Matter/toxicity ; Animals ; Mice ; Rats ; Humans

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Skocz do pozycji: 4.

Tytuł:: Neuroprotection: Rescue from Neuronal Death in the Brain 2.0.
Autorzy:: Lee BH; Department of Physiology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.; Department of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 09; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:: Editorial
MeSH Terms:: Neuroprotection*
Neuroprotective Agents*/pharmacology
Neurons ; Cell Death ; Brain

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Skocz do pozycji: 5.

Tytuł:: Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury.
Autorzy:: Zhang C; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China.; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Li D; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China.; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Hu H; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China.; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Wang Z; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China.; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
An J; Pharmacy School, Jinzhou Medical University, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Gao Z; Pharmacy School, Jinzhou Medical University, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Zhang K; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China.; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China.
Mei X; Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Renmin Street, Jinzhou, 121002, Liaoning, China. .; Key Laboratory of Medical Tissue Engineering of Liaoning Province, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China. .
Wu C; Pharmacy School, Jinzhou Medical University, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China. .
Tian H; Department of Histology and Embryology, Jinzhou Medical University, No. 40, Songpo Road, Jinzhou, 121002, Liaoning, China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2021 Nov 17; Vol. 19 (1), pp. 373. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/pharmacology
Neuroprotective Agents*/chemistry
Neuroprotective Agents*/pharmacology
Extracellular Vesicles/*chemistry
Macrophages/*drug effects
Neuroprotection/*drug effects
Spinal Cord Injuries/*metabolism
Animals ; Biocompatible Materials/chemistry ; Biocompatible Materials/pharmacology ; Curcumin/chemistry ; Curcumin/pharmacology ; Male ; Mice ; Mice, Inbred C57BL

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Skocz do pozycji: 6.

Tytuł:: Hypothermia Induced by Oxcarbazepine after Transient Forebrain Ischemia Exerts Therapeutic Neuroprotection through Transient Receptor Potential Vanilloid Type 1 and 4 in Gerbils.
Autorzy:: Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan 31116, Chungnam, Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Lim SS; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 27; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 27.
Typ publikacji:: Journal Article
MeSH Terms:: Hypothermia, Induced*
Neuroprotection*/drug effects
Ischemia/*therapy
Neuroprotective Agents/*therapeutic use
Oxcarbazepine/*therapeutic use
Prosencephalon/*pathology
TRPV Cation Channels/*metabolism
Animals ; Body Temperature/drug effects ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cognition/drug effects ; Gerbillinae ; Hippocampus/drug effects ; Hippocampus/pathology ; Ischemia/pathology ; Ischemia/physiopathology ; Male ; Neurons/drug effects ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Oxcarbazepine/pharmacology ; Prosencephalon/drug effects ; Prosencephalon/physiopathology

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Skocz do pozycji: 7.

Tytuł:: Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca Overload for the Treatment of Neurodegenerative Diseases and Stroke.
Autorzy:: Viejo L; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Rubio-Alarcón M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Arribas RL; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Moreno-Castro M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Pérez-Marín R; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Braun-Cornejo M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Estrada-Valencia M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
de Los Ríos C; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jul 24; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 24.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/chemical synthesis
Neuroprotective Agents*/pharmacology
Thiazepines*/chemical synthesis
Thiazepines*/pharmacology
Neurodegenerative Diseases/*drug therapy
Neurons/*drug effects
Neuroprotection/*drug effects
Stroke/*drug therapy
Animals ; Calcium/metabolism ; Calcium Channel Blockers/chemical synthesis ; Calcium Channel Blockers/pharmacology ; Calcium Signaling/drug effects ; Cell Line, Tumor ; Female ; Humans ; Mitochondria ; Neurons/pathology ; Rats

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Skocz do pozycji: 8.

Tytuł:: Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury.
Autorzy:: Wei P; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Wang K; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Luo C; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Huang Y; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Misilimu D; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Wen H; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Jin P; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Li C; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Gong Y; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China. gong_.
Gao Y; Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2021 Jun 15; Vol. 18 (1), pp. 137. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Brain Injuries, Traumatic/*complications
Brain Injuries, Traumatic/*drug therapy
Deoxyadenosines/*therapeutic use
Neuroinflammatory Diseases/*prevention & control
Neuroprotection/*drug effects
Neutrophil Infiltration/*drug effects
Animals ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/pathology ; Brain/drug effects ; Brain/pathology ; Deoxyadenosines/pharmacology ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; Neuroinflammatory Diseases/etiology ; Neuroinflammatory Diseases/pathology

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Skocz do pozycji: 9.

Tytuł:: Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models.
Autorzy:: Chamorro B; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, 28040, Madrid, Spain.; Faculty of Health, Camilo José Cela University of Madrid (UCJC), Madrid, Spain.
Diez-Iriepa D; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.; Department of Organic Chemistry and Inorganic Chemistry, Alcalá University, 28805, Alcalá de Henares, Madrid, Spain.
Merás-Sáiz B; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
Chioua M; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
García-Vieira D; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
Iriepa I; Department of Organic Chemistry and Inorganic Chemistry, Alcalá University, 28805, Alcalá de Henares, Madrid, Spain.; Institute of Chemical Research Andrés M. del Río, Alcalá University, 28805, Alcalá de Henares, Madrid, Spain.
Hadjipavlou-Litina D; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
López-Muñoz F; Faculty of Health, Camilo José Cela University of Madrid (UCJC), Madrid, Spain.; Neuropsychopharmacology Unit, 'Hospital 12 de Octubre' Research Institute, Madrid, Spain.
Martínez-Murillo R; Neurovascular Research Group, Department of Translational Neurobiology, Cajal Institute (CSIC), Madrid, Spain. .
Gonzàlez-Nieto D; Center for Biomedical Technology (CTB), Universidad Politécnica de Madrid, Madrid, Spain.; Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain.
Fernández I; Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain. .; Departamento de Química Orgánica I and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain. .
Marco-Contelles J; Laboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain. .
Oset-Gasque MJ; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, 28040, Madrid, Spain. .; Instituto Universitario de Investigación en Neuroquímica, Universidad Complutense de Madrid, 28040, Madrid, Spain. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14150. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain Ischemia/*drug therapy
Cyclic N-Oxides/*chemistry
Free Radical Scavengers/*therapeutic use
Neurons/*drug effects
Neuroprotection/*drug effects
Neuroprotective Agents/*therapeutic use
Nitrogen Oxides/*therapeutic use
Animals ; Apoptosis/drug effects ; Brain Ischemia/chemically induced ; Cell Line, Tumor ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Free Radical Scavengers/chemical synthesis ; Free Radical Scavengers/pharmacology ; Glucose/pharmacology ; Infarction, Middle Cerebral Artery/drug therapy ; Lipid Peroxidation/drug effects ; Lipoxygenase Inhibitors/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Molecular Structure ; Neuroblastoma/pathology ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/pharmacology ; Nitrogen Oxides/chemical synthesis ; Nitrogen Oxides/pharmacology ; Oligomycins/toxicity ; Oxygen/pharmacology ; Rotenone/toxicity

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Skocz do pozycji: 10.

Tytuł:: Inhaled H 2 or CO 2 Do Not Augment the Neuroprotective Effect of Therapeutic Hypothermia in a Severe Neonatal Hypoxic-Ischemic Encephalopathy Piglet Model.
Autorzy:: Kovács V; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.
Remzső G; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.
Tóth-Szűki V; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.
Varga V; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.
Németh J; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.
Domoki F; Department of Physiology, University of Szeged Faculty of Medicine, H-6720 Szeged, Hungary.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 16; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: Hypothermia, Induced*
Asphyxia Neonatorum/*therapy
Brain Damage, Chronic/*prevention & control
Carbon Dioxide/*therapeutic use
Hydrogen/*therapeutic use
Hypoxia-Ischemia, Brain/*therapy
Neuroprotection/*drug effects
Neuroprotective Agents/*therapeutic use
Acidosis/blood ; Acidosis/etiology ; Acidosis/prevention & control ; Administration, Inhalation ; Animals ; Animals, Newborn ; Apoptosis Inducing Factor/biosynthesis ; Apoptosis Inducing Factor/genetics ; Asphyxia Neonatorum/complications ; Asphyxia Neonatorum/drug therapy ; Brain Damage, Chronic/etiology ; Brain-Derived Neurotrophic Factor/biosynthesis ; Brain-Derived Neurotrophic Factor/genetics ; Carbon Dioxide/administration & dosage ; Carbon Dioxide/toxicity ; Caspase 3/biosynthesis ; Caspase 3/genetics ; Caudate Nucleus/pathology ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Electroencephalography ; Evoked Potentials, Visual/drug effects ; Gene Expression Regulation/drug effects ; Hippocampus/pathology ; Hydrogen/administration & dosage ; Hydrogen/analysis ; Hypoxia-Ischemia, Brain/complications ; Hypoxia-Ischemia, Brain/drug therapy ; Hypoxia-Ischemia, Brain/pathology ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Neuroprotective Agents/administration & dosage ; Organ Specificity ; Random Allocation ; Swine

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Skocz do pozycji: 11.

Tytuł:: Pharmacologic neuroprotection in ischemic brain injury after cardiac arrest.
Autorzy:: Katz A; Department of Pharmacy, NYU Langone Health, New York, New York.
Brosnahan SB; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, New York.
Papadopoulos J; Department of Pharmacy, NYU Langone Health, New York, New York.
Parnia S; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, New York.
Lam JQ; Division of Pulmonary and Critical Care, Department of Medicine, Kaiser Permanente South Sacramento Medical Center, Sacramento, California.; Pokaż więcej
Źródło:: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2022 Jan; Vol. 1507 (1), pp. 49-59. Date of Electronic Publication: 2021 May 31.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Brain Injuries/*prevention & control
Brain Ischemia/*prevention & control
Heart Arrest/*drug therapy
Neuroprotection/*drug effects
Neuroprotective Agents/*administration & dosage
Animals ; Antioxidants/administration & dosage ; Brain Injuries/etiology ; Brain Injuries/metabolism ; Brain Ischemia/etiology ; Brain Ischemia/metabolism ; Heart Arrest/complications ; Heart Arrest/metabolism ; Humans ; Memantine/administration & dosage ; Neuroprotection/physiology ; Nitriles/administration & dosage ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Pyridones/administration & dosage ; Thiamine/administration & dosage

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Skocz do pozycji: 12.

Tytuł:: Antibiotics and the Nervous System-Which Face of Antibiotic Therapy Is Real, Dr. Jekyll (Neurotoxicity) or Mr. Hyde (Neuroprotection)?
Autorzy:: Hurkacz M; Department of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Clinical Pharmacy Service, Jan Mikulicz-Radecki University Clinical Hospital, 50-556 Wroclaw, Poland.
Dobrek L; Department of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Wiela-Hojeńska A; Department of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 09; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 09.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Nervous System*/metabolism
Nervous System*/pathology
Neurotoxicity Syndromes*/metabolism
Neurotoxicity Syndromes*/pathology
Neuroprotection/*drug effects
Neuroprotective Agents/*therapeutic use
Animals ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Humans

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Skocz do pozycji: 13.

Tytuł:: Hypoxia Tolerant Species: The Wisdom of Nature Translated into Targets for Stroke Therapy.
Autorzy:: Del Río C; Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Montaner J; Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, Spain.; Department of Neurology, Hospital Universitario Virgen Macarena, 41009 Seville, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hypoxia/*pathology
Neuroprotection/*physiology
Stroke/*therapy
Animals ; Brain Injuries/pathology ; Brain Injuries/therapy ; Caenorhabditis elegans ; Drosophila ; Humans ; Hypoxia/therapy ; Models, Biological ; Molecular Targeted Therapy/methods ; Molecular Targeted Therapy/trends ; Neuroprotective Agents/isolation & purification ; Neuroprotective Agents/metabolism ; Neuroprotective Agents/therapeutic use ; Species Specificity ; Stroke/pathology

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Skocz do pozycji: 14.

Tytuł:: Natural Products and Neuroprotection.
Autorzy:: Angeloni C; School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Vauzour D; Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 07; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 07.
Typ publikacji:: Editorial
MeSH Terms:: Neuroprotection*
Biological Products/*therapeutic use
Neurodegenerative Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Animals ; Biological Products/chemistry ; Humans ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology ; Neuroprotective Agents/chemistry

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Tytuł:: Novel application of amino-acid buffered solution for neuroprotection against ischemia/reperfusion injury.
Autorzy:: Hsu J; Department of Cardiovascular Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Wang CH; Department of Cardiovascular Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Huang SC; Department of Cardiovascular Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Chen YW; Department of Cardiovascular Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Yu S; Department of Cardiovascular Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Hwang JJ; Department of Cardiovascular Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Lin JW; Department of Cardiovascular Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Ma MC; School of Medicine, Fu Jen Catholic University, New Taipei, Taiwan.
Chen YS; Department of Cardiovascular Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Sep 10; Vol. 14 (9), pp. e0221039. Date of Electronic Publication: 2019 Sep 10 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amino Acids/*pharmacology
Neuroprotection/*drug effects
Neuroprotective Agents/*pharmacology
Reperfusion Injury/*prevention & control
Amino Acids/chemistry ; Animals ; Asphyxia/complications ; Asphyxia/metabolism ; Biomarkers ; Buffers ; Disease Models, Animal ; Hydrogen Peroxide/metabolism ; Hydrogen Peroxide/pharmacology ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Male ; NADPH Oxidase 4/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Neuroprotective Agents/chemistry ; Oxidative Stress ; Rats ; Reperfusion Injury/etiology ; Reperfusion Injury/metabolism

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Skocz do pozycji: 16.

Tytuł:: Neuroprotective and Anti-Amyloid β Effect and Main Chemical Profiles of White Tea: Comparison Against Green, Oolong and Black Tea.
Autorzy:: Li X; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; Discipline of Pharmacology, School of Medical Sciences, Faculty of Health Sciences, The University of Adelaide, South Australia 5000, Australia. .
Smid SD; Discipline of Pharmacology, School of Medical Sciences, Faculty of Health Sciences, The University of Adelaide, South Australia 5000, Australia. .
Lin J; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; Fujian Institute of Microbiology, Fuzhou 350007, China. .
Gong Z; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. zhihong_.
Chen S; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
You F; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
Zhang Y; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
Hao Z; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
Lin H; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
Yu X; FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .
Jin X; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 May 19; Vol. 24 (10). Date of Electronic Publication: 2019 May 19.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Amyloid beta-Peptides/*drug effects
Neuroprotection/*drug effects
Neuroprotective Agents/*chemistry
Plant Extracts/*chemistry
Tea/*chemistry
Camellia sinensis/chemistry ; Cell Line ; Cell Survival/drug effects ; Chromatography, High Pressure Liquid/methods ; Humans ; Hydrogen Peroxide/chemistry ; Kinetics ; Neurons/cytology ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; Principal Component Analysis/methods ; Tandem Mass Spectrometry/methods ; Tea/parasitology

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Skocz do pozycji: 17.

Tytuł:: Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity.
Autorzy:: Menchinskaya E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Chingizova E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Pislyagin E; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Likhatskaya G; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Sabutski Y; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Pelageev D; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.; School of Natural Sciences, Far Eastern Federal University, Ajax Bay, Russky Island, 690922 Vladivostok, Russia.
Polonik S; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.
Aminin D; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, 690022 Vladivostok, Russia.; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 14; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 14.
Typ publikacji:: Journal Article
MeSH Terms:: Models, Biological*
Neuroprotection*/drug effects
Naphthoquinones/*pharmacology
Neuroprotective Agents/*pharmacology
Neurotoxins/*toxicity
Oxidopamine/*toxicity
Paraquat/*toxicity
Animals ; Biphenyl Compounds/chemistry ; Cell Cycle/drug effects ; Cell Line ; Cell Survival/drug effects ; Free Radical Scavengers/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Nitric Oxide/biosynthesis ; Picrates/chemistry ; Quantitative Structure-Activity Relationship ; Reactive Oxygen Species/metabolism ; Reproducibility of Results

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Skocz do pozycji: 18.

Tytuł:: Evaluating Neuroprotective Effects of Uridine, Erythropoietin, and Therapeutic Hypothermia in a Ferret Model of Inflammation-Sensitized Hypoxic-Ischemic Encephalopathy.
Autorzy:: Corry KA; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
White OR; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Shearlock AE; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Moralejo DH; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Law JB; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Snyder JM; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.
Juul SE; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.; Center on Human Development and Disability, University of Washington, Seattle, WA 98195, USA.
Wood TR; Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.; Center on Human Development and Disability, University of Washington, Seattle, WA 98195, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 11; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 11.
Typ publikacji:: Evaluation Study; Journal Article
MeSH Terms:: Hypothermia, Induced*
Neuroprotection*
Erythropoietin/*pharmacology
Hypoxia-Ischemia, Brain/*therapy
Neuroprotective Agents/*pharmacology
Uridine/*pharmacology
Animals ; Disease Models, Animal ; Ferrets ; Hypoxia-Ischemia, Brain/metabolism ; Hypoxia-Ischemia, Brain/pathology

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Skocz do pozycji: 19.

Tytuł:: Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?
Autorzy:: Lerouet D; UMR-S1144 - Optimisation Thérapeutique en Neuropsychopharmacologie, Faculté de Pharmacie de Paris, Université de Paris, Paris, France.
Marchand-Leroux C; UMR-S1144 - Optimisation Thérapeutique en Neuropsychopharmacologie, Faculté de Pharmacie de Paris, Université de Paris, Paris, France.
Besson VC; UMR-S1144 - Optimisation Thérapeutique en Neuropsychopharmacologie, Faculté de Pharmacie de Paris, Université de Paris, Paris, France.; Pokaż więcej
Źródło:: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2021 Jun; Vol. 35 (3), pp. 524-538. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Brain Injuries, Traumatic/*drug therapy
Brain Injuries, Traumatic/*physiopathology
Neuroprotection/*physiology
Neuroprotective Agents/*pharmacology
Neuroprotective Agents/*therapeutic use
Age Factors ; Animals ; Clinical Trials as Topic ; Disease Models, Animal ; Drug Evaluation, Preclinical

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Skocz do pozycji: 20.

Tytuł:: Neuroprotection: Rescue from Neuronal Death in the Brain.
Autorzy:: Lee BH; Department of Physiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 03722, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 24; Vol. 22 (11). Date of Electronic Publication: 2021 May 24.
Typ publikacji:: Editorial; Introductory Journal Article
MeSH Terms:: Cell Death*
Neuroprotection*
Neurons/*physiology
Animals ; Humans ; Neuroprotective Agents/pharmacology

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