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Wyszukujesz frazę ""Neurotensin"" wg kryterium: Temat


Tytuł :
Neurotensin receptors regulate transactivation of the EGFR and HER2 in a reactive oxygen species-dependent manner.
Autorzy :
Moody TW; National Institutes of Health, National Cancer Institute, Center for Cancer Research, Bethesda, MD, 20892, USA. Electronic address: .
Lee L; National Institute of Diabetes, Digestive and Kidney Disease, Digestive Diseases Branch, Bethesda, MD, 20892, USA.
Ramos-Alvarez I; National Institute of Diabetes, Digestive and Kidney Disease, Digestive Diseases Branch, Bethesda, MD, 20892, USA.
Jensen RT; National Institute of Diabetes, Digestive and Kidney Disease, Digestive Diseases Branch, Bethesda, MD, 20892, USA.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2019 Dec 15; Vol. 865, pp. 172735. Date of Electronic Publication: 2019 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Transcriptional Activation*/drug effects
ErbB Receptors/*genetics
Reactive Oxygen Species/*metabolism
Receptor, ErbB-2/*genetics
Receptors, Neurotensin/*metabolism
Cell Line, Tumor ; Extracellular Signal-Regulated MAP Kinases/chemistry ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Lapatinib/pharmacology ; Neurotensin/pharmacology ; Phosphorylation/drug effects ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł :
Pro-neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease.
Autorzy :
Tönjes A; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Hoffmann A; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Kralisch S; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.
Qureshi AR; Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Klöting N; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.
Scholz M; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.; Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Schleinitz D; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.
Bachmann A; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Kratzsch J; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.
Nowicki M; nstitute of Anatomy, University of Leipzig, Leipzig, Germany.
Paeschke S; nstitute of Anatomy, University of Leipzig, Leipzig, Germany.
Wirkner K; Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Enzenbach C; Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Baber R; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Beige J; Division of Nephrology and KfH Renal Unit, Hospital St. Georg, Leipzig, Germany.; Martin-Luther-University Halle/Wittenberg, Halle, Germany.
Anders M; Outpatient Nephrology Care Unit, Leipzig, Germany.
Bast I; Outpatient Nephrology Care Unit, Leipzig, Germany.
Blüher M; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig, Leipzig, Germany.
Kovacs P; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.
Löffler M; Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Zhang MZ; Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, C3121 MCN, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University School of Medicine, Nashville Veterans Affairs Hospital, Nashville, Tennessee, USA.
Harris RC; Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, C3121 MCN, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University School of Medicine, Nashville Veterans Affairs Hospital, Nashville, Tennessee, USA.
Stenvinkel P; Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Stumvoll M; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Fasshauer M; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.; Institute of Nutritional Science, Justus-Liebig-University, Giessen, Germany.
Ebert T; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; Leipzig University Medical Center, IFB AdiposityDiseases, Leipzig, Germany.; Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
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Źródło :
European journal of endocrinology [Eur J Endocrinol] 2020 Sep; Vol. 183 (3), pp. 233-244.
Typ publikacji :
Journal Article
MeSH Terms :
Neurotensin/*metabolism
Renal Insufficiency, Chronic/*metabolism
Renal Insufficiency, Chronic/*mortality
Adult ; Aged ; Aged, 80 and over ; Animals ; Cross-Sectional Studies ; Female ; Glomerular Filtration Rate/physiology ; Humans ; Kidney/metabolism ; Kidney/physiopathology ; Longitudinal Studies ; Male ; Meta-Analysis as Topic ; Mice ; Middle Aged ; Neurotensin/blood ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/physiopathology
Czasopismo naukowe
Tytuł :
Novel stable analogues of the neurotensin C-terminal hexapeptide containing unnatural amino acids.
Autorzy :
Magafa V; Department of Pharmacy, University of Patras, 26504, Rion, Greece. .
Matsoukas MT; Department of Pharmacy, University of Patras, 26504, Rion, Greece.
Karageorgos V; Department of Pharmacology, Faculty of Medicine, University of Crete, 71003, Heraklion, Crete, Greece.
Dermitzaki E; Department of Clinical Chemistry, School of Medicine, University of Crete, 71003, Heraklion, Crete, Greece.
Exarchakou R; Department of Pharmacy, University of Patras, 26504, Rion, Greece.
Stylos EΚ; Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.
Pardalos M; Department of Pharmacology, Faculty of Medicine, University of Crete, 71003, Heraklion, Crete, Greece.
Margioris AN; Department of Clinical Chemistry, School of Medicine, University of Crete, 71003, Heraklion, Crete, Greece.
Varvounis G; Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.
Tzakos AG; Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.
Spyroulias GA; Department of Pharmacy, University of Patras, 26504, Rion, Greece.
Liapakis G; Department of Pharmacology, Faculty of Medicine, University of Crete, 71003, Heraklion, Crete, Greece. .
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Źródło :
Amino acids [Amino Acids] 2019 Jul; Vol. 51 (7), pp. 1009-1022. Date of Electronic Publication: 2019 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*chemistry
Neurotensin/*chemistry
Peptidomimetics/*chemical synthesis
Peptidomimetics/*metabolism
Amino Acid Sequence ; Chemistry Techniques, Synthetic ; Chromatography, High Pressure Liquid ; HT29 Cells ; Humans ; Mass Spectrometry ; Models, Molecular ; Molecular Dynamics Simulation ; Peptidomimetics/pharmacology ; Receptors, Neurotensin/chemistry
Czasopismo naukowe
Tytuł :
Ψ-Xenin-6 enhances sitagliptin effectiveness, but does not improve glucose tolerance.
Autorzy :
Craig SL; SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, UK.
Gault VA; SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, UK.
Hamscher G; Institute of Food Chemistry and Food Biotechnology, Justus Liebig University Giessen, Giessen, Germany.
Irwin N; SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, UK.
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Źródło :
The Journal of endocrinology [J Endocrinol] 2020 May; Vol. 245 (2), pp. 219-230.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Gastrointestinal Hormones/*pharmacology
Hypoglycemic Agents/*pharmacology
Neurotensin/*analogs & derivatives
Sitagliptin Phosphate/*pharmacology
Animals ; Blood Glucose/drug effects ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/etiology ; Diet, High-Fat ; Disease Models, Animal ; Drug Therapy, Combination ; Insulin/blood ; Insulin Resistance ; Mice ; Neurotensin/pharmacology
Czasopismo naukowe
Tytuł :
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.
Autorzy :
Richner M; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Pallesen LT; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Ulrichsen M; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Poulsen ET; Department of Molecular Biology and Genetics, Aarhus University, Denmark.
Holm TH; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Login H; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Castonguay A; CERVO Brain Research Centre, Québec Mental Health Institute, Québec, QC, Canada.; Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, Canada.
Lorenzo LE; CERVO Brain Research Centre, Québec Mental Health Institute, Québec, QC, Canada.; Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, Canada.
Gonçalves NP; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Andersen OM; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Lykke-Hartmann K; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Enghild JJ; Department of Molecular Biology and Genetics, Aarhus University, Denmark.
Rønn LCB; Neurodegeneration Disease Biology Unit, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
Malik IJ; Neurodegeneration Disease Biology Unit, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
De Koninck Y; CERVO Brain Research Centre, Québec Mental Health Institute, Québec, QC, Canada.; Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, Canada.
Bjerrum OJ; Department of Drug Design and Pharmacology, University of Copenhagen, Denmark.
Vægter CB; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.
Nykjær A; The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, Denmark.; Danish Research Institute of Translational Neuroscience (DANDRITE)-Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Denmark.; The Danish National Research Foundation Center, PROMEMO, Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark.
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Źródło :
Science advances [Sci Adv] 2019 Jun 19; Vol. 5 (6), pp. eaav9946. Date of Electronic Publication: 2019 Jun 19 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Vesicular Transport/*metabolism
Brain-Derived Neurotrophic Factor/*metabolism
Neuralgia/*metabolism
Neurotensin/*metabolism
Animals ; Down-Regulation/physiology ; Female ; Humans ; Hyperalgesia/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Peripheral Nerve Injuries/metabolism ; Receptors, Neurotensin/metabolism ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia.
Autorzy :
Eiselt E; Département de pharmacologie et physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé , Université de Sherbrooke , Sherbrooke , Québec J1H 5H4 , Canada.
Gonzalez S; Research Group of Organic Chemistry, Departments of Bioengineering Sciences and Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels 1050 , Belgium.
Martin C; Research Group of Organic Chemistry, Departments of Bioengineering Sciences and Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels 1050 , Belgium.
Chartier M; Département de pharmacologie et physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé , Université de Sherbrooke , Sherbrooke , Québec J1H 5H4 , Canada.
Betti C; Research Group of Organic Chemistry, Departments of Bioengineering Sciences and Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels 1050 , Belgium.
Longpré JM; Département de pharmacologie et physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé , Université de Sherbrooke , Sherbrooke , Québec J1H 5H4 , Canada.
Cavelier F; Institut des Biomolécules Max Mousseron, IBMM, UMR 5247, CNRS, Université de Montpellier, ENSCM , Place Eugène Bataillon , 34095 Montpellier Cedex 5, France.
Tourwé D; Research Group of Organic Chemistry, Departments of Bioengineering Sciences and Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels 1050 , Belgium.
Gendron L; Département de pharmacologie et physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé , Université de Sherbrooke , Sherbrooke , Québec J1H 5H4 , Canada.
Ballet S; Research Group of Organic Chemistry, Departments of Bioengineering Sciences and Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels 1050 , Belgium.
Sarret P; Département de pharmacologie et physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé , Université de Sherbrooke , Sherbrooke , Québec J1H 5H4 , Canada.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2019 Nov 20; Vol. 10 (11), pp. 4535-4544. Date of Electronic Publication: 2019 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Analgesia/*methods
Hypotension/*metabolism
Hypothermia/*metabolism
Neurotensin/*analogs & derivatives
Receptors, Neurotensin/*metabolism
Tyrosine/*metabolism
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Dose-Response Relationship, Drug ; Humans ; Hypotension/chemically induced ; Hypothermia/chemically induced ; Male ; Neurotensin/toxicity ; Pain Measurement/drug effects ; Pain Measurement/methods ; Protein Binding/drug effects ; Protein Binding/physiology ; Rats ; Rats, Sprague-Dawley ; Receptors, Neurotensin/agonists ; Tyrosine/genetics
Czasopismo naukowe
Tytuł :
Structure of the neurotensin receptor 1 in complex with β-arrestin 1.
Autorzy :
Huang W; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Masureel M; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Qu Q; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Janetzko J; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Kato HE; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Komaba Institute for Science, The University of Tokyo, Tokyo, Japan.
Robertson MJ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Nguyen KC; Departments of Medicine and Microbiology & Immunology, Stanford University, Stanford, CA, USA.
Glenn JS; Departments of Medicine and Microbiology & Immunology, Stanford University, Stanford, CA, USA.
Skiniotis G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Photon Science, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA, USA. .
Kobilka BK; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło :
Nature [Nature] 2020 Mar; Vol. 579 (7798), pp. 303-308. Date of Electronic Publication: 2020 Jan 16.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Molecular*
Receptors, Neurotensin/*chemistry
beta-Arrestin 1/*chemistry
Cryoelectron Microscopy ; Humans ; Phosphorylation ; Protein Stability ; Protein Structure, Quaternary ; Receptors, Neurotensin/metabolism ; beta-Arrestin 1/metabolism
Czasopismo naukowe
Tytuł :
Ligand-mediated dephosphorylation signaling for MAP kinase.
Autorzy :
Shults NV; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20007, USA.
Almansour FS; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20007, USA.
Rybka V; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20007, USA.
Suzuki DI; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20007, USA.
Suzuki YJ; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20007, USA. Electronic address: .
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Źródło :
Cellular signalling [Cell Signal] 2018 Dec; Vol. 52, pp. 147-154. Date of Electronic Publication: 2018 Sep 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Endothelial Cells/*metabolism
Myocytes, Smooth Muscle/*metabolism
Neurotensin/*physiology
Peptide Fragments/*physiology
Pulmonary Artery/*metabolism
Endothelial Cells/cytology ; Humans ; Intracellular Signaling Peptides and Proteins/pharmacology ; MAP Kinase Signaling System ; Myocytes, Smooth Muscle/cytology ; Peptidylprolyl Isomerase/antagonists & inhibitors ; Protease Nexins/metabolism ; Pulmonary Artery/cytology ; RNA-Binding Proteins ; Receptors, Neurotensin/metabolism
Czasopismo naukowe
Tytuł :
Neurotensin and dynorphin Bi-Directionally modulate CeA inhibition of oval BNST neurons in male mice.
Autorzy :
Normandeau CP; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Torruella Suárez ML; Program in Neurobiology, School of Medicine, University of North Carolina at Chapel Hill, USA.
Sarret P; Department of Pharmacology & Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
McElligott ZA; Bowles Center for Alcohol Studies and Departments of Psychiatry and Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, USA.
Dumont EC; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2018 Dec; Vol. 143, pp. 113-121. Date of Electronic Publication: 2018 Sep 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Central Amygdaloid Nucleus/*metabolism
Dynorphins/*metabolism
Neural Inhibition/*physiology
Neurons/*metabolism
Neurotensin/*metabolism
Septal Nuclei/*metabolism
Animals ; Central Amygdaloid Nucleus/cytology ; Central Amygdaloid Nucleus/drug effects ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Neural Inhibition/drug effects ; Neurons/cytology ; Neurons/drug effects ; Neurotransmitter Agents/pharmacology ; RNA, Messenger/metabolism ; Receptors, GABA-A/metabolism ; Receptors, Neurotensin/metabolism ; Receptors, Opioid, kappa/metabolism ; Septal Nuclei/cytology ; Septal Nuclei/drug effects ; Synapses/drug effects ; Synapses/metabolism ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology ; Tissue Culture Techniques ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł :
Development of [ F]AlF-NOTA-NT as PET Agents of Neurotensin Receptor-1 Positive Pancreatic Cancer.
Autorzy :
Wang M; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
Zhang H; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.; Department of Radiology, Obstetrics and Gynecology Hospital , Fudan University , No. 419 Fang xie Road , Shanghai 200011 , People's Republic of China.
Wang H; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
Feng H; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.; ZhuJiang Hospital of Southern Medical University , Guangzhou , Guangdong 510280 , People's Republic of China.
Deng H; PET/CT Center , The First Affiliated Hospital of Guangzhou Medical University , Guangzhou , Guangdong 510230 , People's Republic of China.
Wu Z; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
Lu H; Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering , Nanjing University , Nanjing 210093 , China.
Li Z; Biomedical Research Imaging Center and Department of Radiology , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
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Źródło :
Molecular pharmaceutics [Mol Pharm] 2018 Aug 06; Vol. 15 (8), pp. 3093-3100. Date of Electronic Publication: 2018 Jun 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Pancreatic Ductal/*diagnostic imaging
Pancreatic Neoplasms/*diagnosis
Radiopharmaceuticals/*administration & dosage
Receptors, Neurotensin/*metabolism
Aluminum/administration & dosage ; Aluminum/chemistry ; Animals ; Carcinoma, Pancreatic Ductal/pathology ; Cell Line, Tumor ; Fluorine/administration & dosage ; Fluorine/chemistry ; Fluorine Radioisotopes/administration & dosage ; Fluorine Radioisotopes/chemistry ; Heterocyclic Compounds, 1-Ring/administration & dosage ; Heterocyclic Compounds, 1-Ring/chemistry ; Humans ; Mice ; Mice, Nude ; Molecular Imaging/methods ; Molecular Targeted Therapy/methods ; Neurotensin/administration & dosage ; Neurotensin/chemistry ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/therapy ; Positron-Emission Tomography/methods ; Radiopharmaceuticals/chemistry ; Receptors, Neurotensin/antagonists & inhibitors ; Theranostic Nanomedicine/methods ; X-Ray Microtomography/methods ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Neurotensin receptor 1 is a new therapeutic target for human undifferentiated pleomorphic sarcoma growth.
Autorzy :
Tokumoto H; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Setoguchi T; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.; Department of Orthopaedic Surgery, Japanese Red Cross Kagoshima Hospital, Kagoshima, Japan.
Saitoh Y; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Sasaki H; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Nagano S; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Maeda S; Department of Medical Joint Materials, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Tanimoto A; Department of Pathology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Taniguchi N; Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.; Department of Medical Joint Materials, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2019 Dec; Vol. 58 (12), pp. 2230-2240. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic/*genetics
Receptors, Neurotensin/*genetics
Sarcoma/*genetics
Up-Regulation/*genetics
Adult ; Aged ; Aged, 80 and over ; Animals ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cell Survival/drug effects ; Cell Survival/genetics ; Drug Synergism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Molecular Targeted Therapy/methods ; Panobinostat/pharmacology ; Pyrazoles/pharmacology ; Quinolines/pharmacology ; Receptors, Neurotensin/antagonists & inhibitors ; Receptors, Neurotensin/metabolism ; Sarcoma/drug therapy ; Sarcoma/metabolism ; Up-Regulation/drug effects ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Virtual screening of a natural compound library at orthosteric and allosteric binding sites of the neurotensin receptor.
Autorzy :
Rejwan Ali M; Department of Physics, St John's University , Queens , NY , USA.
Sadoqi M; Department of Physics, St John's University , Queens , NY , USA.; Department of Pharmaceutical Sciences, St John's University , Queens , NY , USA.
Boutajangout A; Department of Neurology and Neuroscience & Physiology and Psychiatry, New York University Langone Medical Center , New York , NY , USA.
Mezei M; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai , New York , NY , USA.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2019 Oct; Vol. 37 (17), pp. 4494-4506. Date of Electronic Publication: 2019 Jan 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Evaluation, Preclinical*
Biological Products/*analysis
Biological Products/*metabolism
Receptors, Neurotensin/*metabolism
Allosteric Regulation ; Allosteric Site ; Animals ; Binding Sites ; Cluster Analysis ; Hydrogen Bonding ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Rats ; Receptors, Neurotensin/agonists ; Receptors, Neurotensin/antagonists & inhibitors ; Thermodynamics ; Time Factors
Czasopismo naukowe
Tytuł :
Evaluation of neurotensin receptor 1 as potential biomarker for prostate cancer theranostic use.
Autorzy :
He T; PET Center of Xiangya Hospital, Central South University, Changsha, China.
Wang M; Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wang H; Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Tan H; PET Center of Xiangya Hospital, Central South University, Changsha, China.
Tang Y; PET Center of Xiangya Hospital, Central South University, Changsha, China.
Smith E; Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wu Z; Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Liao W; Department of Radiology of Xiangya Hospital, Central South University, Changsha, China. .
Hu S; PET Center of Xiangya Hospital, Central South University, Changsha, China. .
Li Z; Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. .
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Źródło :
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2019 Sep; Vol. 46 (10), pp. 2199-2207. Date of Electronic Publication: 2019 Jul 01.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Carcinoma/*diagnostic imaging
Neurotensin/*analogs & derivatives
Prostatic Neoplasms/*diagnostic imaging
Radiopharmaceuticals/*pharmacokinetics
Receptors, Neurotensin/*genetics
Aged ; Animals ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma/genetics ; Carcinoma/metabolism ; Cell Line, Tumor ; Humans ; Male ; Mice ; Middle Aged ; Neurotensin/metabolism ; Positron-Emission Tomography/methods ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Neurotensin/metabolism ; Theranostic Nanomedicine/methods
Czasopismo naukowe
Tytuł :
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake.
Autorzy :
Xiao Y; Department of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Institute for Pediatric Research, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Yan W; Department of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Lu Y; Shanghai Institute for Pediatric Research, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Zhou K; Shanghai Institute for Pediatric Research, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Cai W; Department of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Institute for Pediatric Research, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2018 Sep; Vol. 35, pp. 133-141. Date of Electronic Publication: 2018 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Bile Acids and Salts/*metabolism
Intestinal Diseases/*complications
Liver Diseases/*etiology
Neurotensin/*blood
Absorption, Physiological ; Animals ; Blood Glucose/metabolism ; Cell Line ; Child ; Cytokines/blood ; Homeostasis ; Humans ; Ileum/metabolism ; Infant ; Intestinal Diseases/blood ; Lipids/blood ; Liver Diseases/blood ; Male ; Mice, Inbred C57BL ; Models, Biological ; Organic Anion Transporters, Sodium-Dependent/metabolism ; Receptors, Neurotensin/metabolism ; Symporters/metabolism ; Taurocholic Acid/metabolism
Czasopismo naukowe
Tytuł :
A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Autorzy :
Yin W; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Li Z; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Jin M; National Center for Protein Science Shanghai, State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Yin YL; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
de Waal PW; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
Pal K; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.; Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India.
Yin Y; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
Gao X; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
He Y; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.; Laboratory of Receptor Structure and Signaling, HIT Center for Life Science, Harbin Institute of Technology, Harbin, 150001, China.
Gao J; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Wang X; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Zhang Y; Department of Pathology of Sir Run Run Shaw Hospital and Department of Biophysics, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Zhou H; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Melcher K; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
Jiang Y; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Cong Y; National Center for Protein Science Shanghai, State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. .
Edward Zhou X; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA. .
Yu X; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. .; Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. .
Eric Xu H; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. .; Center for Cancer and Cell Biology, Program for Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA. .
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Źródło :
Cell research [Cell Res] 2019 Dec; Vol. 29 (12), pp. 971-983. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Neurotensin*/chemistry
Receptors, Neurotensin*/metabolism
beta-Arrestin 2*/chemistry
beta-Arrestin 2*/metabolism
Humans ; Molecular Docking Simulation/methods ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
Beneficial Effects of Neurotensin in Murine Model of Hapten-Induced Asthma.
Autorzy :
Russjan E; Department of Respiration Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawińskiego Street, 02-106 Warsaw, Poland. .
Kaczyńska K; Department of Respiration Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawińskiego Street, 02-106 Warsaw, Poland. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Oct 11; Vol. 20 (20). Date of Electronic Publication: 2019 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*administration & dosage
Asthma/*drug therapy
Haptens/*adverse effects
Neurotensin/*administration & dosage
Animals ; Anti-Inflammatory Agents/pharmacology ; Asthma/chemically induced ; Asthma/immunology ; Bronchoalveolar Lavage Fluid/chemistry ; Bronchoalveolar Lavage Fluid/immunology ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Humans ; Injections, Intraperitoneal ; Leukocytes/drug effects ; Leukocytes/metabolism ; Male ; Methacholine Chloride/administration & dosage ; Methacholine Chloride/therapeutic use ; Mice ; Mice, Inbred BALB C ; Neurotensin/pharmacology ; Pyrazoles/administration & dosage ; Pyrazoles/pharmacology ; Quinolines/administration & dosage ; Quinolines/pharmacology
Czasopismo naukowe
Tytuł :
Effects of an enzymatically stable C-terminal hexapseudopeptide fragment peptide of xenin-25, ψ-xenin-6, on pancreatic islet function and metabolism.
Autorzy :
Craig SL; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Gault VA; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
McClean S; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Hamscher G; Institute of Food Chemistry and Food Biotechnology, Justus Liebig University Giessen, Germany.
Irwin N; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK. Electronic address: .
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Źródło :
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2019 Oct 01; Vol. 496, pp. 110523. Date of Electronic Publication: 2019 Jul 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypoglycemic Agents*/chemistry
Hypoglycemic Agents*/pharmacology
Neurotensin*/chemistry
Neurotensin*/pharmacology
Glucagon/*metabolism
Insulin Secretion/*drug effects
Insulin-Secreting Cells/*metabolism
Animals ; Cell Line ; Glucose/pharmacology ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Optimization and CH 3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies.
Autorzy :
Bumbak F; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.
Keen AC; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia.
Gunn NJ; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia; IBM Research Australia, Southbank, Victoria 3053, Australia.
Gooley PR; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address: .
Bathgate RAD; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address: .
Scott DJ; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2018 Jun; Vol. 1860 (6), pp. 1372-1383. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nuclear Magnetic Resonance, Biomolecular/*methods
Receptors, Neurotensin/*chemistry
Animals ; Carbon Isotopes ; Circular Dichroism ; Detergents/pharmacology ; Escherichia coli ; Hot Temperature ; Isotope Labeling ; Ligands ; Methionine/chemistry ; Models, Molecular ; Neurotensin/metabolism ; Protein Binding ; Protein Conformation ; Protein Stability ; Rats ; Receptors, Neurotensin/drug effects ; Receptors, Neurotensin/genetics ; Receptors, Neurotensin/metabolism ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/isolation & purification ; Scattering, Small Angle ; Signal Transduction ; Solubility ; X-Ray Diffraction
Czasopismo naukowe
Tytuł :
Dynamic tuneable G protein-coupled receptor monomer-dimer populations.
Autorzy :
Dijkman PM; Biomembrane Structure Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; Max Planck Institute for Biophysics, Max-von-Laue-Straße 3, 60438, Frankfurt am Main, Germany.
Castell OK; Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; School of Pharmacy and Pharmaceutical Sciences, College of Biomedical and Life Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
Goddard AD; Biomembrane Structure Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK.
Munoz-Garcia JC; Biomembrane Structure Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
de Graaf C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Wallace MI; Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK. .; Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, London, SE1 1DB, UK. .
Watts A; Biomembrane Structure Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK. .
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Źródło :
Nature communications [Nat Commun] 2018 Apr 27; Vol. 9 (1), pp. 1710. Date of Electronic Publication: 2018 Apr 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Dynamics Simulation*
Protein Multimerization/*physiology
Receptors, Neurotensin/*metabolism
Fluorescence Resonance Energy Transfer/methods ; Lipid Bilayers/metabolism ; Monte Carlo Method ; Neurotensin/metabolism ; Receptors, Neurotensin/agonists ; Receptors, Neurotensin/genetics ; Single Molecule Imaging/methods
Czasopismo naukowe

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