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Tytuł :
Association between social psychological status and efavirenz and nevirapine plasma concentration among HIV patients in Kenya.
Autorzy :
Ngayo MO; Centre of Microbiology Research, Kenya Medical Research Institute, Complex off Ngong Road Box, Nairobi, 19464-00202, Kenya. .; Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya. .
Oluka M; Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya.
Bulimo WD; Department of Biochemistry, University of Nairobi, Nairobi, Kenya.
Okalebo FA; Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya.
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Źródło :
Scientific reports [Sci Rep] 2021 Nov 11; Vol. 11 (1), pp. 22071. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alkynes/*therapeutic use
Anti-HIV Agents/*therapeutic use
Benzoxazines/*therapeutic use
Cyclopropanes/*therapeutic use
HIV Infections/*drug therapy
Nevirapine/*therapeutic use
Adult ; Alkynes/blood ; Anti-HIV Agents/blood ; Benzoxazines/blood ; Cross-Sectional Studies ; Cyclopropanes/blood ; Female ; HIV Infections/epidemiology ; Humans ; Kenya/epidemiology ; Male ; Middle Aged ; Nevirapine/blood ; Socioeconomic Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Could pharmacogenetics aid the prediction of nevirapine pharmacokinetics and allow individualized treatment?
Autorzy :
Kwara A; Department of Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
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Źródło :
Pharmacogenomics [Pharmacogenomics] 2021 Sep; Vol. 22 (14), pp. 881-884. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-HIV Agents/*pharmacokinetics
HIV Infections/*genetics
HIV Infections/*metabolism
Nevirapine/*pharmacokinetics
Pharmacogenetics/*methods
Precision Medicine/*methods
Anti-HIV Agents/therapeutic use ; Cytochrome P-450 CYP2B6/genetics ; Cytochrome P-450 CYP2B6/metabolism ; HIV Infections/drug therapy ; Humans ; Nevirapine/therapeutic use ; Predictive Value of Tests
Raport
Tytuł :
Trough plasma nevirapine levels, immunologic and virologic responses in composite CYP2B6*6/*18 HIV-infected adult Nigerian patients.
Autorzy :
Abdullahi ST; Department of Pharmaceutical and Medicinal Chemistry, University of Ilorin, Ilorin, Nigeria.; Department of Pharmaceutical Chemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
Soyinka JO; Department of Pharmaceutical Chemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
Bolarinwa RA; Department of Haematology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Olarewaju OJ; Department of Haematology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Salami AK; Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Bakare-Odunola MT; Department of Pharmaceutical and Medicinal Chemistry, University of Ilorin, Ilorin, Nigeria.
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Źródło :
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2022 Jul; Vol. 131 (1), pp. 45-52. Date of Electronic Publication: 2022 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/therapeutic use
HIV Infections*/complications
HIV Infections*/drug therapy
Adult ; Cytochrome P-450 CYP2B6/genetics ; Humans ; Nevirapine/therapeutic use ; Nigeria ; RNA/therapeutic use ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Maternal Human Immunodeficiency Virus (HIV) Drug Resistance Is Associated With Vertical Transmission and Is Prevalent in Infected Infants.
Autorzy :
Boyce CL; Department of Global Health, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Sils T; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Ko D; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Wong-On-Wing A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Beck IA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Styrchak SM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
DeMarrais P; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Tierney C; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Stranix-Chibanda L; University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Flynn PM; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Taha TE; Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA.
Owor M; Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Fowler MG; Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA.
Frenkel LM; Department of Global Health, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics and Laboratory Medicine, University of Washington, Seattle, Washington, USA.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Jun 10; Vol. 74 (11), pp. 2001-2009.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV Infections*/prevention & control
Pregnancy Complications, Infectious*/drug therapy
Breast Feeding ; Case-Control Studies ; Drug Resistance ; Female ; HIV ; Humans ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Nevirapine/therapeutic use ; Pregnancy ; RNA/therapeutic use
Czasopismo naukowe
Tytuł :
The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies.
Autorzy :
Marinho AT; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal.
Batuca JR; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal.
Miranda JP; Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, Lisbon, 1649-003, Portugal.
Caixas U; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal; Centro Hospitalar de Lisboa Central (CHLC), Lisbon, 1150-199, Portugal.
Dias CG; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal.
Branco T; Hospital Prof. Doutor Fernando Fonseca (HFF), Amadora, 2720-276, Portugal.
Soto K; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal; Hospital Prof. Doutor Fernando Fonseca (HFF), Amadora, 2720-276, Portugal.
Pinheiro P; Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, Lisbon, 1649-003, Portugal.
Bourbon M; Unidade de Investigação & Desenvolvimento, Grupo de Investigação Cardiovascular, Departamento de Promoção da Saúde e Prevenção de Doenças Não Transmissíveis, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisbon, Portugal.
Marques MM; Centro de Química Estrutural (CQE), Instituto Superior Técnico, Universidade de Lisboa, Lisbon, 1049-001, Portugal.
Antunes AM; Centro de Química Estrutural (CQE), Instituto Superior Técnico, Universidade de Lisboa, Lisbon, 1049-001, Portugal.
Monteiro EC; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal.
Pereira SA; Chronic Diseases Research Centre, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, Lisbon, 1169-056, Portugal. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2021 Mar; Vol. 165, pp. 105446. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents/*metabolism
Anti-HIV Agents/*pharmacology
Apolipoprotein A-I/*blood
Cholesterol, HDL/*blood
Nevirapine/*metabolism
Nevirapine/*pharmacology
Adult ; Aged ; Animals ; Anti-HIV Agents/therapeutic use ; Apolipoprotein A-I/agonists ; Cells, Cultured ; Cholesterol, HDL/antagonists & inhibitors ; Cross-Sectional Studies ; Female ; HIV Infections/blood ; HIV Infections/drug therapy ; HIV-1/drug effects ; Hep G2 Cells ; Humans ; Male ; Middle Aged ; Nevirapine/therapeutic use ; Pilot Projects ; Prospective Studies ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Acquired HIV drug resistance among adults living with HIV receiving first-line antiretroviral therapy in Rwanda: A cross-sectional nationally representative survey.
Autorzy :
Musengimana G; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Tuyishime E; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Kiromera A; 3489University of Maryland, Center for International Health, Education and Biosecurity, (CIHEB), Baltimore, MD USA.
Malamba SS; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Mulindabigwi A; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Habimana MR; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Baribwira C; 3489University of Maryland, Center for International Health, Education and Biosecurity, (CIHEB), Baltimore, MD USA.
Ribakare M; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Habimana SD; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
DeVos J; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Atlanta, GA USA.
Mwesigwa RCN; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Kayirangwa E; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Semuhore JM; World Health Organization, Rwanda Office.
Rwibasira GN; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Suthar AB; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Atlanta, GA USA.
Remera E; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.; University of Basel, Basel, Switzerland.; Swiss Tropical and Public Health Institute, Basel, Switzerland.
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Źródło :
Antiviral therapy [Antivir Ther] 2022 Jun; Vol. 27 (3), pp. 13596535221102690.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV-1*/genetics
Adult ; Anti-Retroviral Agents/pharmacology ; Anti-Retroviral Agents/therapeutic use ; Cross-Sectional Studies ; Drug Resistance, Viral/genetics ; Humans ; Lamivudine/therapeutic use ; Nevirapine/therapeutic use ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Rwanda/epidemiology ; Viral Load ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Incidence and predictors of nevirapine and efavirenz-associated rash among Indonesian HIV patients.
Autorzy :
Hasan M; Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala/ZainoelAbidin Hospital, Aceh, Indonesia.; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/CiptoMangunkusumo Hospital, Jakarta, Indonesia.
Yunihastuti E; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/CiptoMangunkusumo Hospital, Jakarta, Indonesia.
Teguh H K; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/CiptoMangunkusumo Hospital, Jakarta, Indonesia.
Abdullah M; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/CiptoMangunkusumo Hospital, Jakarta, Indonesia.
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Źródło :
Asian Pacific journal of allergy and immunology [Asian Pac J Allergy Immunol] 2022 Jun; Vol. 40 (2), pp. 141-146.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/adverse effects
Coinfection*/complications
Coinfection*/drug therapy
Exanthema*/chemically induced
Exanthema*/drug therapy
Exanthema*/epidemiology
HIV Infections*/complications
HIV Infections*/drug therapy
Hepatitis C*/drug therapy
Alkynes ; Benzoxazines ; CD4 Lymphocyte Count ; Cyclopropanes ; Female ; Humans ; Incidence ; Indonesia/epidemiology ; Male ; Nevirapine/adverse effects ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Improved Hematologic Outcomes in HIV1-Exposed Infants Receiving Nevirapine Compared With Zidovudine for Postnatal Prophylaxis in a High Resource Setting.
Autorzy :
Dollfus C; From the Service d'Hématologie et Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, APHP Sorbonne Université, Paris, France.
Le Chenadec J; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.
Mandelbrot L; Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, APHP Nord Université de Paris, Colombes, France.; INSERM, UMR1137-IAME, Université de Paris, Paris, France.
Tubiana R; Service de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, APHP Sorbonne Université, Paris, France.; INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Université, Paris, France.
Faye A; Service de Pédiatrie Générale, Hôpital Robert Debré, APHP Nord Université de Paris, Paris, France.
Brossard M; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.; APHP, Service de Santé Publique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Frange P; Service de Microbiologie clinique, Hôpital Necker Enfants-Malades, APHP Centre Université de Paris, Paris, France.; EHU 7328 PACT, Institut Imagine, Université de Paris, Paris, France.
Blanche S; Service d'Immunologie Pédiatrique, Hôpital Necker Enfants Malades, APHP Centre Université de Paris, Paris, France.
Warszawski J; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.; APHP, Service de Santé Publique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France; and The ANRS CO1/CO11 study group members are listed in the Acknowledgments.
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Corporate Authors :
ANRS CO1/CO11 study group
Źródło :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2022 May 01; Vol. 41 (5), pp. 420-423.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/prevention & control
Pregnancy Complications, Infectious*/drug therapy
Female ; Humans ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Nevirapine/therapeutic use ; Pregnancy ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Pharmacokinetics and safety of early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: a phase 1/2 proof of concept study.
Autorzy :
Ruel TD; University of California San Francisco, San Francisco, CA, USA. Electronic address: .
Capparelli EV; University of California San Diego, La Jolla, CA, USA.
Tierney C; Harvard TH Chan School of Public Health, Boston, MA, USA.
Nelson BS; Harvard TH Chan School of Public Health, Boston, MA, USA.
Coletti A; FHI 360, Durham, NC, USA.
Bryson Y; University of Los Angeles, Los Angeles, CA, USA.
Cotton MF; Stellenbosch University, Tygerberg, South Africa.
Spector SA; University of California San Diego, La Jolla, CA, USA.
Mirochnick M; Boston University School of Medicine, Boston, MA, USA.
LeBlanc R; Frontier Science and Technology Research Foundation, Amherst, NY, USA.
Reding C; Frontier Science and Technology Research Foundation, Amherst, NY, USA.
Zimmer B; Frontier Science and Technology Research Foundation, Amherst, NY, USA.
Persaud D; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bwakura-Dangarembizi M; University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Naidoo KL; Nelson R Mandela School of Medicine, Durban, South Africa.
Hazra R; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Jean-Philippe P; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Chadwick EG; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
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Źródło :
The lancet. HIV [Lancet HIV] 2021 Mar; Vol. 8 (3), pp. e149-e157. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-HIV Agents/*adverse effects
Anti-HIV Agents/*pharmacokinetics
HIV Infections/*drug therapy
Nevirapine/*adverse effects
Nevirapine/*pharmacokinetics
Reverse Transcriptase Inhibitors/*therapeutic use
Anti-HIV Agents/therapeutic use ; Female ; Gestational Age ; HIV Infections/transmission ; Humans ; Infant ; Infant, Newborn ; Infectious Disease Transmission, Vertical ; Male ; Nevirapine/therapeutic use ; Pregnancy ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/virology ; Proof of Concept Study ; Prospective Studies ; Reverse Transcriptase Inhibitors/adverse effects ; Reverse Transcriptase Inhibitors/pharmacokinetics
Czasopismo naukowe
Tytuł :
Nevirapine Pharmacokinetics in Neonates Between 25 and 32 Weeks Gestational Age for the Prevention of Mother-to-Child Transmission of HIV.
Autorzy :
Hirt D; From the EA7323, Evaluation des thérapeutiques et pharmacologie périnatale et pédiatrique, Université de Paris and.; Service de Pharmacologie Clinique, AP-HP, Hôpital Cochin, Paris, France.; INSERM, U1018, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
Kubota Kilengelela J; Service de Médecine et Réanimation néonatales de Port-Royal, APHP Centre-Université de Paris, hôpital Cochin-Broca.
Jarreau PH; Service de Médecine et Réanimation néonatales de Port-Royal, APHP Centre-Université de Paris, hôpital Cochin-Broca.; INSERM, INRA, Université de Paris, Centre de Recherche en Epidémiologie et Statistiques/CRESS.
Tréluyer JM; From the EA7323, Evaluation des thérapeutiques et pharmacologie périnatale et pédiatrique, Université de Paris and.; Service de Pharmacologie Clinique, AP-HP, Hôpital Cochin, Paris, France.; INSERM, U1018, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
Marcou V; Service de Médecine et Réanimation néonatales de Port-Royal, APHP Centre-Université de Paris, hôpital Cochin-Broca.
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Źródło :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2021 Apr 01; Vol. 40 (4), pp. 344-346.
Typ publikacji :
Journal Article
MeSH Terms :
Gestational Age*
Anti-HIV Agents/*pharmacokinetics
HIV Infections/*prevention & control
HIV-1/*drug effects
Infectious Disease Transmission, Vertical/*prevention & control
Nevirapine/*pharmacokinetics
Pregnancy Complications, Infectious/*prevention & control
Pregnancy Complications, Infectious/*virology
Administration, Oral ; Anti-HIV Agents/administration & dosage ; Female ; HIV Infections/drug therapy ; HIV Infections/transmission ; Humans ; Infant, Newborn ; Nevirapine/administration & dosage ; Pregnancy
Czasopismo naukowe
Tytuł :
Advancing knowledge in perinatal HIV treatment.
Autorzy :
Waitt C; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GF, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Myer L; Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Khoo S; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GF, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK. Electronic address: .
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Źródło :
The lancet. HIV [Lancet HIV] 2021 Mar; Vol. 8 (3), pp. e124-e125. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
HIV Infections*/drug therapy
HIV Infections*/transmission
Nevirapine*/therapeutic use
Anti-Retroviral Agents/therapeutic use ; Female ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Proof of Concept Study
Czasopismo naukowe
Tytuł :
Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria.
Autorzy :
Usman SO; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria. Electronic address: .
Oreagba IA; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria; West African Postgraduate College of Pharmacists, Yaba, Lagos State, Nigeria; National Agency for Food and Drug Administration and Control, Wuse, Abuja, Nigeria.
Akinyede AA; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Agbaje EO; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Akinleye MO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy of the University of Lagos, Nigeria.
Onwujuobi AG; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Ken-Owotor C; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Adeuja O; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Ogunfowokan T; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Kogbe S; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Owolabi ET; Apin Clinic, Lagos University Teaching Hospital, Idi-Araba, Lagos State, Nigeria.
Adeniji H; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Busari AW; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Hassan OO; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Abideen G; Department of Pharmacology, Therapeutics and Toxicology, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria.
Akanmu AS; Department of Haematology and Blood Transfusion, Faculty of Clinical Science, College of Medicine of the University of Lagos, Idi-Araba, Lagos State, Nigeria; Apin Clinic, Lagos University Teaching Hospital, Idi-Araba, Lagos State, Nigeria.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Nov; Vol. 144 (3), pp. 95-101. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Interactions*
Anti-Retroviral Agents/*adverse effects
Antimalarials/*adverse effects
Artemether, Lumefantrine Drug Combination/*adverse effects
Benzoxazines/*adverse effects
HIV Infections/*drug therapy
Malaria/*drug therapy
Nevirapine/*adverse effects
Adult ; Alkynes ; Anti-Retroviral Agents/administration & dosage ; Anti-Retroviral Agents/blood ; Antimalarials/administration & dosage ; Antimalarials/blood ; Artemether, Lumefantrine Drug Combination/administration & dosage ; Artemether, Lumefantrine Drug Combination/blood ; Benzoxazines/administration & dosage ; Benzoxazines/blood ; Cyclopropanes ; Drug Combinations ; Drug Therapy, Combination ; Female ; HIV Infections/complications ; Humans ; Lopinavir ; Malaria/complications ; Male ; Middle Aged ; Nevirapine/administration & dosage ; Nevirapine/blood ; Nigeria ; Ritonavir ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
The role of CYP2B6 516G>T polymorphism on efavirenz/nevirapine toxicity. Implications on treatment outcomes: Lessons from Botswana.
Autorzy :
Maseng MJ; School of Allied Health Professions, Faculty of Health Sciences, University of Botswana, UB Campus, Block 246, Gaborone, Botswana.; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.
Tawe L; School of Allied Health Professions, Faculty of Health Sciences, University of Botswana, UB Campus, Block 246, Gaborone, Botswana.; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Botswana-University of Pennsylvania Partnership, UB Campus, Block 244G, Gaborone, Botswana.
Thami PK; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town, South Africa.
Moyo S; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Hungtinton Avenue, Boston, MA.
Kasvosve I; School of Allied Health Professions, Faculty of Health Sciences, University of Botswana, UB Campus, Block 246, Gaborone, Botswana.
Novitsky V; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Hungtinton Avenue, Boston, MA.
Essex M; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Hungtinton Avenue, Boston, MA.
Russo G; Department of Public Health and Infectious Disease, Faculty of Medicine, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome, Italy.
Gaseitsiwe S; Botswana-Harvard AIDS Institute Partnership, Plot 1836 North Ring Road, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Hungtinton Avenue, Boston, MA.
Paganotti GM; Botswana-University of Pennsylvania Partnership, UB Campus, Block 244G, Gaborone, Botswana.; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, 3120-2740 Hamilton Walk, Philadelphia, PA.; Department of Biomedical Sciences, Faculty of Medicine, University of Botswana, UB Campus, Block 246, Gaborone, Botswana.
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Źródło :
Medicine [Medicine (Baltimore)] 2022 Apr 29; Vol. 101 (17), pp. e29066. Date of Electronic Publication: 2022 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/adverse effects
HIV Infections*/drug therapy
HIV Infections*/genetics
Alkynes ; Benzoxazines/toxicity ; Botswana ; Cyclopropanes ; Cytochrome P-450 CYP2B6/genetics ; Genotype ; Humans ; Leukocytes, Mononuclear ; Nevirapine/toxicity ; Polymorphism, Single Nucleotide ; Retrospective Studies ; Reverse Transcriptase Inhibitors/toxicity
Czasopismo naukowe
Tytuł :
Predictors of mortality among adolescents and young adults living with HIV on antiretroviral therapy in Dar es Salaam, Tanzania: a retrospective cohort study.
Autorzy :
Amour MA; Department of Community Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Shayo GA; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Matee MM; Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Machumi L; Management and Development for Health, Dar es Salaam, Tanzania.
Rugarabamu A; Management and Development for Health, Dar es Salaam, Tanzania.
Aris EA; Management and Development for Health, Dar es Salaam, Tanzania.
Sunguya BF; Department of Community Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Mugusi FM; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
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Źródło :
Journal of the International AIDS Society [J Int AIDS Soc] 2022 Feb; Vol. 25 (2), pp. e25886.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
HIV Infections*/drug therapy
Adolescent ; CD4 Lymphocyte Count ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Nevirapine ; Retrospective Studies ; Tanzania/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Pharmacogenetic interactions of rifapentine plus isoniazid with efavirenz or nevirapine.
Autorzy :
Haas DW; Department of Medicine, Vanderbilt University School of Medicine.
Podany AT; Department of Pharmacy Practice and Science, Antiviral Pharmacology Laboratory, UNMC Center for Drug Discovery, University of Nebraska Medical Center, Omaha.
Bao Y; Statistical and Data Analysis Center, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Swindells S; Infectious Diseases, Internal Medicine, University of Nebraska Medical Center, Omaha.
Chaisson RE; Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mwelase N; Helen Joseph Hospital, University of Witwatersrand University, Johannesburg, South Africa.
Supparatpinyo K; Department of Medicine, Research Institute for Health Sciences and Faculty of Medicine, Chiang Mai University, Thailand.
Mohapi L; Perinatal HIV Research Unit, University of the Witwatersrand and Chris Hani Baragwanath Hospital, Soweto, South Africa.
Gupta A; Department of Medicine, Center for Clinical Global Health Education, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Benson CA; Departments of Medicine and Global Public Health, Antiviral Research Center, University of California, San Diego.
Baker P; Vanderbilt Technologies for Advanced Genomics, Vanderbilt University Medical Center, Nashville, Tennessee.
Fletcher CV; Department of Pharmacy Practice and Science, Antiviral Pharmacology Laboratory, UNMC Center for Drug Discovery, University of Nebraska Medical Center, Omaha; for the AIDS Clinical Trials Group A5279 Study Team.
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Źródło :
Pharmacogenetics and genomics [Pharmacogenet Genomics] 2021 Jan; Vol. 31 (1), pp. 17-27.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alkynes/*administration & dosage
Benzoxazines/*administration & dosage
Cyclopropanes/*administration & dosage
HIV Infections/*drug therapy
Isoniazid/*administration & dosage
Nevirapine/*administration & dosage
Rifampin/*analogs & derivatives
Adolescent ; Adult ; Alkynes/adverse effects ; Anti-HIV Agents/administration & dosage ; Arylamine N-Acetyltransferase/genetics ; Benzoxazines/adverse effects ; Cyclopropanes/adverse effects ; Drug Synergism ; HIV Infections/genetics ; HIV Infections/virology ; Humans ; Isoniazid/adverse effects ; Male ; Middle Aged ; Nevirapine/adverse effects ; Pharmacogenetics ; Rifampin/administration & dosage ; Rifampin/adverse effects ; Young Adult
Czasopismo naukowe
Tytuł :
Effects of CYP2B6 polymorphisms on plasma nevirapine concentrations: a systematic review and meta-analysis.
Autorzy :
Yoon HY; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Republic of Korea.
Cho YA; College of Pharmacy, Gyeongsang National University, Jinju, Gyeongnam, 52828, Republic of Korea.; Mokhwa Convalescent Hospital, Jinju, Gyeongnam, 52828, Republic of Korea.
Yee J; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Republic of Korea. .
Gwak HS; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 15; Vol. 10 (1), pp. 17390. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Polymorphism, Genetic*
Cytochrome P-450 CYP2B6/*genetics
Nevirapine/*blood
Reverse Transcriptase Inhibitors/*blood
HIV Infections/drug therapy ; Humans ; Nevirapine/therapeutic use ; Reverse Transcriptase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine.
Autorzy :
Tateishi Y; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan.
Ohe T; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan. Electronic address: .
Yasuda D; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan.
Takahashi K; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan.
Nakamura S; Department of Chemistry, Nippon Medical School, 1-7-1 Kyonan-cho, Musashino, Tokyo, Japan.
Kazuki Y; Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, 86 Nishi-cho, Yonago, Tottori, Japan; Chromosome Engineering Research Center (CERC), Tottori University, 86 Nishi-cho, Yonago, Tottori, Japan.
Mashino T; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan.
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Źródło :
Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Apr; Vol. 35 (2), pp. 238-243. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Nevirapine/*metabolism
Reverse Transcriptase Inhibitors/*metabolism
Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Hep G2 Cells ; Humans ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; Molecular Structure ; Nevirapine/chemical synthesis ; Nevirapine/pharmacology ; Reverse Transcriptase Inhibitors/chemical synthesis ; Reverse Transcriptase Inhibitors/pharmacology ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
HIV Encephalopathy in ART-Naïve, Hospitalized Infants in Mozambique.
Autorzy :
Chaúque S; H ospital Central de Maputo, Maputo, Mozambique.
Mohole J; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Zucula H; Hospital Central de Beira, Beira, Mozambique.
Lambo L; H ospital Central de Maputo, Maputo, Mozambique.
Lisboa A; H ospital Central de Maputo, Maputo, Mozambique.
Ferreira D; Hospital Central de Beira, Beira, Mozambique.
Nguyen H; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Chowdhary H; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Macmillian B; Hospital Central de Beira, Beira, Mozambique.
Elias B; H ospital Central de Maputo, Maputo, Mozambique.
Seni A; Hospital Central de Beira, Beira, Mozambique.
Buck WC; H ospital Central de Maputo, Maputo, Mozambique.; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
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Źródło :
Journal of tropical pediatrics [J Trop Pediatr] 2021 Dec 08; Vol. 67 (6).
Typ publikacji :
Journal Article
MeSH Terms :
AIDS Dementia Complex*/drug therapy
Anti-HIV Agents*/therapeutic use
HIV Infections*/complications
HIV Infections*/diagnosis
HIV Infections*/drug therapy
Pregnancy Complications, Infectious*/drug therapy
Child ; Female ; Humans ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Mozambique/epidemiology ; Nevirapine/therapeutic use ; Pregnancy
Czasopismo naukowe
Tytuł :
High nevirapine levels in breast milk and consequences in HIV-infected child when initiated on antiretroviral therapy.
Autorzy :
Pressiat C; Pharmacology Department, AP-HP, Hôpitaux Universitaires Henri Mondor, Paris Est-Créteil University, Créteil.
Toni TD; Centre de Diagnostic et de Recherche sur le Sida (CeDReS), Centre Hospitalier Universitaire Treichville, Abidjan, Côte d'Ivoire.
Treluyer JM; Paris Descartes University, EA 7323.; Clinical Pharmacology Department, AP-HP, Paris Centre Hospital Group, Paris.
Yonaba C; Pediatric Department, Centre Hospitalier Universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
Dahourou DL; MONOD Project, ANRS 12206, Centre de Recherche Internationale pour la Santé, Ouagadougou.; Centre Muraz, Bobo-Dioulasso, Burkina Faso.; Institut de Recherche en Sciences de la Santé (IRSS), Ouagadougou.; University of Bordeaux, Inserm, Institut de Recherche pour le Développement (IRD), UMR 1219, Bordeaux.
Malateste K; University of Bordeaux, Inserm, Institut de Recherche pour le Développement (IRD), UMR 1219, Bordeaux.
Seguin-Devaux C; Luxembourg Institute of Health, Luxembourg.
Leroy V; CERPOP, Inserm, Université de Toulouse, Université Paul Sabatier, Toulouse.; Valériane Leroy and Déborah Hirt have contributed equally to the work.
Hirt D; Paris Descartes University, EA 7323.; Clinical Pharmacology Department, AP-HP, Paris Centre Hospital Group, Paris.; Inserm 1018 CESP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; Valériane Leroy and Déborah Hirt have contributed equally to the work.
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Corporate Authors :
MONOD ANRS Study Group
Źródło :
AIDS (London, England) [AIDS] 2021 Nov 15; Vol. 35 (14), pp. 2409-2410.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/adverse effects
HIV Infections*/drug therapy
Child ; Female ; Humans ; Infectious Disease Transmission, Vertical/prevention & control ; Milk, Human ; Nevirapine/adverse effects
Raport
Tytuł :
Eco-friendly synthesis of phthalate angico gum towards nanoparticles engineering using Quality by Design (QbD) approach.
Autorzy :
de Oliveira TC; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Oliveira ACJ; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Patriota YBG; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Chaves LL; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Ribeiro FOS; Research Center on Biodiversity and Biotechnology - BIOTEC, Federal University of Delta of Parnaiba, Parnaiba, PI, Brazil.
de Paula RCM; Department of Organic and Inorganic Chemistry, Federal University of Ceara, Fortaleza, CE, Brazil.
Silva-Filho EC; Interdisciplinary Laboratory for Advanced Materials - LIMAV, Federal University of Piaui, Teresina, PI, Brazil.
da Silva DA; Research Center on Biodiversity and Biotechnology - BIOTEC, Federal University of Delta of Parnaiba, Parnaiba, PI, Brazil.
Soares MFR; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Soares-Sobrinho JL; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Nov 01; Vol. 190, pp. 801-809. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Green Chemistry Technology*
Nanotechnology*
Nanoparticles/*chemistry
Phthalic Acids/*chemistry
Plant Gums/*chemistry
Drug Liberation ; Humans ; Microscopy, Atomic Force ; Molecular Weight ; Nevirapine/pharmacology ; Particle Size ; Proton Magnetic Resonance Spectroscopy ; Solubility ; Spectroscopy, Fourier Transform Infrared ; Thermogravimetry ; X-Ray Diffraction
Czasopismo naukowe

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