Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Newgard, Christopher B."" wg kryterium: Autor


Tytuł :
Maternal Metabolites Associated with Gestational Diabetes Mellitus and a Postpartum Disorder of Glucose Metabolism.
Autorzy :
Liu Y; Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China.; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff, Chicago, IL, USA.
Kuang A; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.
Ilkayeva OR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Lowe LP; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Metzger BE; Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Scholtens DM; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Lowe WL; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff, Chicago, IL, USA.
Pokaż więcej
Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Jul 13. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Association of Life-Course Educational Attainment and Breast Cancer Grade in the MEND Study.
Autorzy :
Gupta A; Trinity College of Arts and Sciences, Duke University, Durham, NC, USA.; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Jones K; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Deveaux A; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Bevel M; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Salako O; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Daramola A; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Hall A; Department of Pathology, School of Medicine, Duke University, Durham, NC, USA.
Alatise O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Ogun G; Unversity College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Adeniyi A; Federal Medical Center, Abeokuta, Ogun State, Nigeria.
Ojo A; University of Kansas Medical Center, Kansas City, KS, USA.
Ayandipo O; Unversity College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olajide T; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Olasehinde O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Arowolo O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Adisa A; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Afuwape O; Unversity College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olusanya A; Unversity College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Adegoke A; Our Lady of Apostle Catholic Hospital, Ibadan, Oyo State, Nigeria.
Tollefsbol TO; University of Alabama at Birmingham, Birmingham, AL, USA.
Arnett D; University of Kentucky, Lexington, KY, USA.
Newgard CB; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Akinyemiju T; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.; Duke Cancer Institute, School of Medicine, Duke University, Durham, NC, USA.; Duke Global Health Institute, Duke University, NC, USA.
Pokaż więcej
Źródło :
Annals of global health [Ann Glob Health] 2021 Jul 07; Vol. 87 (1), pp. 59. Date of Electronic Publication: 2021 Jul 07 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis.
Autorzy :
Lee J; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Vijayakumar A; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
White PJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA.; 3Department of Pharmacology and Cancer Biology, and Department of Medicine, Endocrine Division, Duke University Medical Center, Durham, NC 27701, USA.
Xu Y; Cellular and Molecular Physiology Department, Pennsylvania State University, Hershey, PA 17033, USA.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA.; 3Department of Pharmacology and Cancer Biology, and Department of Medicine, Endocrine Division, Duke University Medical Center, Durham, NC 27701, USA.
Lynch CJ; Cellular and Molecular Physiology Department, Pennsylvania State University, Hershey, PA 17033, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA.; 3Department of Pharmacology and Cancer Biology, and Department of Medicine, Endocrine Division, Duke University Medical Center, Durham, NC 27701, USA.
Kahn BB; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Pokaż więcej
Źródło :
Endocrinology [Endocrinology] 2021 Jul 01; Vol. 162 (7).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study.
Autorzy :
Gupta A; Trinity College of Arts and Sciences, Duke University, Durham, NC, USA.; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Oyekunle T; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Salako O; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Daramola A; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Alatise O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Ogun G; University College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Adeniyi A; Federal Medical Center, Abeokuta, Ogun State, Nigeria.
Deveaux A; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.
Saraiya V; Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Hall A; Department of Pathology, School of Medicine, Duke University, Durham, NC, USA.
Ayandipo O; University College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olajide T; College of Medicine & Lagos University Teaching Hospital, University of Lagos, Lagos State, Nigeria.
Olasehinde O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Arowolo O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Adisa A; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria.
Afuwape O; University College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olusanya A; University College Hospital, University of Ibadan, Ibadan, Oyo State, Nigeria.
Adegoke A; Our Lady of Apostle Catholic Hospital, Ibadan, Oyo State, Nigeria.
Tollefsbol TO; Department of Biology, College of Arts and Sciences, University of Alabama at Birmingham, AL, USA.
Arnett D; College of Public Health, University of Kentucky, Lexington, KY, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
Newgard CB; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
Akinyemiju T; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA.; Duke Cancer Institute, School of Medicine, Duke University, Durham, NC, USA.; Duke Global Health Institute, Duke University, Durham, NC, USA.
Pokaż więcej
Corporate Authors :
H3 Africa Kidney Research Network
Źródło :
Oncotarget [Oncotarget] 2021 Jun 22; Vol. 12 (13), pp. 1230-1242. Date of Electronic Publication: 2021 Jun 22 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions.
Autorzy :
Bihlmeyer NA; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States of America.
Kwee LC; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States of America.
Clish CB; Metabolomics Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Deik AA; Metabolomics Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
Pagidipati NJ; Duke Clinical Research Institute, Duke University, Durham, North Carolina, United States of America.; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.
Laferrère B; Columbia University Irving Medical Center, New York, New York, United States of America.
Svetkey LP; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.
Newgard CB; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States of America.
Kraus WE; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States of America.
Shah SH; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States of America.; Duke Clinical Research Institute, Duke University, Durham, North Carolina, United States of America.; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2021 May 27; Vol. 16 (5), pp. e0240764. Date of Electronic Publication: 2021 May 27 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Gut microbiome contributions to altered metabolism in a pig model of undernutrition.
Autorzy :
Chang HW; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
McNulty NP; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Hibberd MC; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
O'Donnell D; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Cheng J; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Lombard V; Architecture et Fonction des Macromolécules Biologiques, CNRS, Aix-Marseille Université, 13288 Cedex 9 Marseille, France.
Henrissat B; Architecture et Fonction des Macromolécules Biologiques, CNRS, Aix-Marseille Université, 13288 Cedex 9 Marseille, France.; Department of Biological Sciences, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710.; Department of Medicine, Duke University Medical Center, Durham, NC 27710.
Barratt MJ; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Lin X; Laboratory of Developmental Nutrition, North Carolina State University, Raleigh, NC 27695.; Department of Animal Science, North Carolina State University, Raleigh, NC 27695.
Odle J; Laboratory of Developmental Nutrition, North Carolina State University, Raleigh, NC 27695.; Department of Animal Science, North Carolina State University, Raleigh, NC 27695.
Gordon JI; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110; .; Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 May 25; Vol. 118 (21).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street.
Autorzy :
White PJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA.
McGarrah RW; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA.
Herman MA; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA.
Shah SH; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, 27701, USA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, 27701, USA; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC, 27701, USA; Department of Medicine, Divisions of Endocrinology & Metabolism and Cardiology, Duke University Medical Center, Durham, NC, 27701, USA. Electronic address: Chris.Newgard@duke.edu.
Pokaż więcej
Źródło :
Molecular metabolism [Mol Metab] 2021 May 24, pp. 101261. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Autorzy :
Zhang GF; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC 27701, USA.
Jensen MV; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.
Gray SM; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.
El K; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.
Wang Y; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.
Lu D; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.
Becker TC; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC 27701, USA.
Campbell JE; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC 27701, USA; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27701, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC 27701, USA; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27701, USA. Electronic address: chris.newgard@duke.edu.
Pokaż więcej
Źródło :
Cell metabolism [Cell Metab] 2021 Apr 06; Vol. 33 (4), pp. 804-817.e5. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes.
Autorzy :
Pathmanapan S; Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
Ilkayeva O; Department of Pharmacology & Cancer Biology, Duke University, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Martin JT; Department of Orthopaedic Surgery, Duke University, 311 Trent, Durham, NC, 27710, USA.
Loe AKH; Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, ON, Canada.
Zhang H; Department of Orthopaedic Surgery, Duke University, 311 Trent, Durham, NC, 27710, USA.
Zhang GF; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Newgard CB; Department of Pharmacology & Cancer Biology, Duke University, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Wunder JS; Lunenfeld-Tanenbaum Research Institute, and the University Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, ON, Canada.
Alman BA; Department of Orthopaedic Surgery, Duke University, 311 Trent, Durham, NC, 27710, USA. .
Pokaż więcej
Źródło :
Cancer & metabolism [Cancer Metab] 2021 Mar 24; Vol. 9 (1), pp. 13. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
Autorzy :
Walejko JM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Christopher BA; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
Crown SB; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Zhang GF; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Pickar-Oliver A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Yoneshiro T; UCSF Diabetes Center, San Francisco, CA, USA.
Foster MW; Duke Proteomics and Metabolomics Shared Resource, Duke University School of Medicine, Durham, NC, USA.
Page S; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
van Vliet S; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Ilkayeva O; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Carson MW; Eli Lilly and Company, Indianapolis, IN, US.
Brozinick JT; Eli Lilly and Company, Indianapolis, IN, US.
Hammond CD; Eli Lilly and Company, Indianapolis, IN, US.
Gimeno RE; Eli Lilly and Company, Indianapolis, IN, US.
Moseley MA; Duke Proteomics and Metabolomics Shared Resource, Duke University School of Medicine, Durham, NC, USA.
Kajimura S; UCSF Diabetes Center, San Francisco, CA, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Newgard CB; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
White PJ; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA. .; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA. .; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. .
McGarrah RW; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA. .; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Mar 15; Vol. 12 (1), pp. 1680. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acids, Branched-Chain/*metabolism
Heart/*physiology
Hemiterpenes/*metabolism
Keto Acids/*metabolism
Animals ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Obesity/metabolism ; Rats ; Valine/metabolism
Czasopismo naukowe
Tytuł :
The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights.
Autorzy :
McCann JR; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Bihlmeyer NA; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Roche K; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Catherine C; Department of Pediatrics, Duke University, Durham, North Carolina, USA.
Jawahar J; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Kwee LC; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Younge NE; Department of Pediatrics, Duke University, Durham, North Carolina, USA.
Silverman J; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Ilkayeva O; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Sarria C; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Zizzi A; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Wootton J; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Poppe L; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Anderson P; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Arlotto M; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Wei Z; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Granek JA; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.; Duke Microbiome Center, Duke University Durham, North Carolina, USA.
Valdivia RH; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.; Duke Microbiome Center, Duke University Durham, North Carolina, USA.
David LA; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.; Duke Microbiome Center, Duke University Durham, North Carolina, USA.
Dressman HK; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.; Duke Microbiome Center, Duke University Durham, North Carolina, USA.
Newgard CB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.
Shah SH; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA.
Seed PC; Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Stanley Manne Children's Research Institute, Northwestern University Medical Center, Chicago, Illinois, USA.
Rawls JF; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.; Duke Microbiome Center, Duke University Durham, North Carolina, USA.
Armstrong SC; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA.
Pokaż więcej
Źródło :
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2021 Mar; Vol. 29 (3), pp. 569-578.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Pediatric Obesity/*metabolism
Pediatric Obesity/*microbiology
Adolescent ; Body Weight/physiology ; Case-Control Studies ; Child ; Fasting ; Feces/microbiology ; Female ; Gastrointestinal Microbiome/genetics ; Gastrointestinal Microbiome/physiology ; Humans ; Male ; Metabolomics/methods ; Preliminary Data ; RNA, Ribosomal, 16S/analysis ; RNA, Ribosomal, 16S/genetics
Czasopismo naukowe
Tytuł :
Metabolites and diabetes remission after weight loss.
Autorzy :
Kwee LC; Duke Molecular Physiology Institute, Durham, NC, USA.
Ilkayeva O; Duke Molecular Physiology Institute, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Durham, NC, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Durham, NC, USA.
Bihlmeyer N; Duke Molecular Physiology Institute, Durham, NC, USA.
Wolfe B; Departments of Surgery and Medicine, Oregon Health & Science University,, Portland, OR, USA.
Purnell JQ; Departments of Surgery and Medicine, Oregon Health & Science University,, Portland, OR, USA.
Xavier Pi-Sunyer F; New York Obesity Research Center, Division of Endocrinology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Chen H; Department of Biostatistics and Data Science, Wake Forest School of Medicine Medical Center, Winston-Salem, NC, USA.
Bahnson J; Department of Biostatistics and Data Science, Wake Forest School of Medicine Medical Center, Winston-Salem, NC, USA.
Newgard CB; Duke Molecular Physiology Institute, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Durham, NC, USA.; Department of Pharmacology & Cancer Biology and Division of Endocrinology, Department of Medicine, Duke University, Durham, DC, USA.
Shah SH; Duke Molecular Physiology Institute, Durham, NC, USA.; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, DC, USA.
Laferrère B; New York Obesity Research Center, Division of Endocrinology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA. .
Pokaż więcej
Źródło :
Nutrition & diabetes [Nutr Diabetes] 2021 Feb 24; Vol. 11 (1), pp. 10. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Efficacy of metformin and fermentable fiber combination therapy in adolescents with severe obesity and insulin resistance: study protocol for a double-blind randomized controlled trial.
Autorzy :
Deehan EC; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Colin-Ramirez E; Department of Pediatrics, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Triador L; Department of Pediatrics, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Madsen KL; Department of Medicine, University of Alberta, Edmonton, T6G 2C2, AB, Canada.
Prado CM; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Field CJ; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Ball GDC; Department of Pediatrics, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Tan Q; Department of Pediatrics, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Orsso C; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Dinu I; School of Public Health, University of Alberta, Edmonton, T6G 1C9, AB, Canada.
Pakseresht M; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, T6G 2E1, AB, Canada.
Rubin D; California State University Fullerton, Fullerton, USA.
Sharma AM; Department of Medicine, University of Alberta, Edmonton, T6G 2C2, AB, Canada.
Tun H; University of Hong Kong School of Public Health, Hong Kong, China.
Walter J; DNational University of Ireland University College Cork, University College Cork, Cork, Ireland.
Newgard CB; Duke University Medical Center, Duke University Hospital, Durham, NC, USA.
Freemark M; Duke University Medical Center, Duke University Hospital, Durham, NC, USA.
Wine E; Department of Pediatrics and Physiology, University of Alberta, Edmonton, T6G 1C9, BA, Canada.
Haqq AM; Department of Pediatrics, University of Alberta, Edmonton, T6G 2E1, AB, Canada. .
Pokaż więcej
Źródło :
Trials [Trials] 2021 Feb 17; Vol. 22 (1), pp. 148. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
Insulin Resistance*
Metformin*/adverse effects
Obesity, Morbid*
Adolescent ; Double-Blind Method ; Humans ; Hypoglycemic Agents/adverse effects ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis.
Autorzy :
Fan L; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Sweet DR; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Prosdocimo DA; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.; The Webb Law Firm, Pittsburgh, Pennsylvania, USA.
Vinayachandran V; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Chan ER; Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.
Zhang R; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Lu Y; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.; Charles River Laboratories, Ashland, Ohio, USA.
Keerthy KS; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Booth CE; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Departments of Medicine and Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.
Jain MK; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Pokaż więcej
Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Feb 15; Vol. 131 (4).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mechanisms controlling pancreatic islet cell function in insulin secretion.
Autorzy :
Campbell JE; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA. chris.newgard@duke.edu.; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC, USA. chris.newgard@duke.edu.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA. chris.newgard@duke.edu.
Pokaż więcej
Źródło :
Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2021 Feb; Vol. 22 (2), pp. 142-158. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Homeostasis*
Insulin Secretion*
Diabetes Mellitus, Type 2/*physiopathology
Glucose/*metabolism
Insulin-Secreting Cells/*physiology
Animals ; Humans ; Insulin-Secreting Cells/cytology
Czasopismo naukowe
Tytuł :
Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.
Autorzy :
White PJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Departments of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Lapworth AL; CV and Metabolic Diseases Research Unit, Pfizer, Cambridge, MA, USA.
McGarrah RW; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Kwee LC; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Crown SB; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
An J; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Carson MW; Diabetes Therapeutic Area, Lilly Research Laboratories, a Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.
Christopher BA; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Ball JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Davies MN; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Kjalarsdottir L; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
George T; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Stevens RD; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Koves TR; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Geriatrics, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Muoio DM; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Departments of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Brozinick JT; Diabetes Therapeutic Area, Lilly Research Laboratories, a Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.
Gimeno RE; Diabetes Therapeutic Area, Lilly Research Laboratories, a Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.
Brosnan MJ; CV and Metabolic Diseases Research Unit, Pfizer, Cambridge, MA, USA.
Rolph TP; CV and Metabolic Diseases Research Unit, Pfizer, Cambridge, MA, USA.
Kraus WE; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Shah SH; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA; Departments of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC, USA. Electronic address: chris.newgard@duke.edu.
Pokaż więcej
Źródło :
Cell reports [Cell Rep] 2020 Nov 10; Vol. 33 (6), pp. 108375.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.
Autorzy :
Huynh FK; Department of Biological Sciences, San Jose State University, San Jose, California.
Peterson BS; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.
Anderson KA; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.
Lin Z; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.
Coakley AJ; Department of Biological Sciences, San Jose State University, San Jose, California.
Llaguno FMS; Department of Biological Sciences, San Jose State University, San Jose, California.
Nguyen TN; Department of Biological Sciences, San Jose State University, San Jose, California.
Campbell JE; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, North Carolina.
Stephens SB; Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Iowa, Carver College of Medicine, Iowa City, Iowa.; Fraternal Order of Eagles Diabetes Research Center, Iowa City, Iowa.
Newgard CB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, North Carolina.
Hirschey MD; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, North Carolina.
Pokaż więcej
Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Oct 01; Vol. 319 (4), pp. E805-E813. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Secretion/*physiology
Insulin-Secreting Cells/*metabolism
Mitochondrial Proteins/*metabolism
Sirtuins/*metabolism
Animals ; Glucose/pharmacology ; Glucose Intolerance/metabolism ; Insulin Resistance ; Islets of Langerhans/cytology ; Islets of Langerhans/metabolism ; Leucine/pharmacology ; Mice ; Mice, Knockout ; Mitochondria/metabolism ; Nutrients ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
Metabolomic and genetic associations with insulin resistance in pregnancy.
Autorzy :
Liu Y; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff 12, 420 E. Superior St, Chicago, IL, 60611, USA.; Department of Endocrinology, South Campus, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Kuang A; Department of Preventive Medicine (Biostatistics), Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA.
Talbot O; Department of Preventive Medicine (Biostatistics), Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA.
Bain JR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Muehlbauer MJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.
Hayes MG; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff 12, 420 E. Superior St, Chicago, IL, 60611, USA.
Ilkayeva OR; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.
Lowe LP; Department of Preventive Medicine (Biostatistics), Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA.
Metzger BE; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff 12, 420 E. Superior St, Chicago, IL, 60611, USA.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Scholtens DM; Department of Preventive Medicine (Biostatistics), Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA. .
Lowe WL Jr; Department of Medicine, Northwestern University Feinberg School of Medicine, Rubloff 12, 420 E. Superior St, Chicago, IL, 60611, USA. .
Pokaż więcej
Corporate Authors :
HAPO Study Cooperative Research Group
Źródło :
Diabetologia [Diabetologia] 2020 Sep; Vol. 63 (9), pp. 1783-1795. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells.
Autorzy :
Hohmeier HE; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Zhang L; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Taylor B; Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.
Stephens S; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Lu D; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
McNamara P; Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.
Laffitte B; Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 Mar 16; Vol. 15 (3), pp. e0224344. Date of Electronic Publication: 2020 Mar 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*drug effects
Insulin Secretion/*drug effects
Insulin-Secreting Cells/*metabolism
Insulinoma/*metabolism
Protein Kinase Inhibitors/*pharmacology
Animals ; Cell Line, Tumor ; Glucagon-Secreting Cells/metabolism ; Glucagon-Secreting Cells/pathology ; Glucose/pharmacology ; Homeodomain Proteins/metabolism ; Humans ; Insulin-Secreting Cells/pathology ; Insulinoma/pathology ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/metabolism ; Protein-Serine-Threonine Kinases/antagonists & inhibitors ; Protein-Serine-Threonine Kinases/metabolism ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Protein-Tyrosine Kinases/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats.
Autorzy :
McGarrah RW; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.; Cardiology Division, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Zhang GF; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.; Endocrinology Division, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Christopher BA; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.; Cardiology Division, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Deleye Y; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
Walejko JM; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
Page S; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
White PJ; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.; Endocrinology Division, Department of Medicine, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.
Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.; Endocrinology Division, Department of Medicine, Duke University Medical Center, Durham, North Carolina.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.
Pokaż więcej
Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Feb 01; Vol. 318 (2), pp. E216-E223. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet*
Amino Acids, Branched-Chain/*deficiency
Myocardium/*metabolism
Obesity/*metabolism
Triglycerides/*metabolism
Acetyl Coenzyme A/metabolism ; Amino Acids, Branched-Chain/blood ; Animals ; Glucose/metabolism ; Male ; Malonyl Coenzyme A/metabolism ; Metabolomics ; Palmitates/metabolism ; Protein Kinases/metabolism ; Rats ; Rats, Zucker
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies