Autor: "Nguyen, Trang T. T." - OpacWWW

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Tytuł:: SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells.
Autorzy:: Wyman AE; Geriatric Research Education and Clinical Center (GRECC), VA Maryland Health Care System, Baltimore VA Medical Center, Baltimore, MD, USA. .; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. .; Research Service, Baltimore VA Medical Center, Baltimore, MD, USA. .; Departments of Medicine and Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA. .
Nguyen TTT; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Karki P; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Tulapurkar ME; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Zhang CO; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Kim J; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Feng TG; Department of Anesthesiology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Dabo AJ; Departments of Medicine and Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Todd NW; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Research Service, Baltimore VA Medical Center, Baltimore, MD, USA.
Luzina IG; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Research Service, Baltimore VA Medical Center, Baltimore, MD, USA.
Geraghty P; Departments of Medicine and Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Foronjy RF; Departments of Medicine and Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Hasday JD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Research Service, Baltimore VA Medical Center, Baltimore, MD, USA.
Birukova AA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Atamas SP; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Research Service, Baltimore VA Medical Center, Baltimore, MD, USA.
Birukov KG; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Jul 27; Vol. 10 (1), pp. 12497. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Capillary Permeability*
Endothelial Cells/*pathology
Epithelium/*pathology
Inflammation/*metabolism
Lung/*pathology
Sirtuins/*deficiency
Adult ; Animals ; Bleomycin ; Cell Membrane Permeability ; Cells, Cultured ; Endothelial Cells/metabolism ; Gene Expression Regulation ; Gene Silencing ; Humans ; Inflammation Mediators/metabolism ; Lipopolysaccharides ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Pulmonary Fibrosis/genetics ; Pulmonary Fibrosis/pathology ; Pulmonary Fibrosis/physiopathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction ; Sirtuins/genetics ; Sirtuins/metabolism ; Transforming Growth Factor beta/metabolism

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