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Tytuł :
Influence of Liver Intoxication by Carbon Tetrachloride or D-Galactosamine on Absorption of Fluorescein Isothiocyanate-Dextran-10 and Other Marker Compounds with Different Molecular Weights from the Rat Liver Surface.
Autorzy :
Miyamoto H; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Tsuda K; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Honda T; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Tokunaga A; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Fumoto S; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Nishida K; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2020; Vol. 43 (2), pp. 319-324.
Typ publikacji :
Journal Article
MeSH Terms :
Carbon Tetrachloride/*toxicity
Dextrans/*metabolism
Fluorescein-5-isothiocyanate/*analogs & derivatives
Galactosamine/*toxicity
Liver/*drug effects
Liver/*metabolism
Animals ; Dextrans/blood ; Fluorescein-5-isothiocyanate/metabolism ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Influence of vasomodulators and tumor transplantation on the disposition of 5-fluorouracil after application to the liver surface in rats.
Autorzy :
Kodama Y; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Horishita M; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Tokunaga A; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Miyamoto H; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Fumoto S; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Sasaki H; Department of Hospital Pharmacy, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Nakamura J; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Nishida K; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
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Źródło :
Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2017 Sep; Vol. 38 (6), pp. 367-372. Date of Electronic Publication: 2017 May 23.
Typ publikacji :
Journal Article
MeSH Terms :
Antimetabolites, Antineoplastic/*pharmacokinetics
Carcinoma 256, Walker/*metabolism
Fluorouracil/*pharmacokinetics
Liver/*metabolism
Vasoconstrictor Agents/*pharmacology
Vasodilator Agents/*pharmacology
Animals ; Cell Line, Tumor ; Epinephrine/pharmacology ; Hydralazine/pharmacology ; Male ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Three-Dimensional Imaging of the Intracellular Fate of Plasmid DNA and Transgene Expression: ZsGreen1 and Tissue Clearing Method CUBIC Are an Optimal Combination for Multicolor Deep Imaging in Murine Tissues.
Autorzy :
Fumoto S; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Nishimura K; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Nishida K; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Kawakami S; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
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Źródło :
PloS one [PLoS One] 2016 Jan 29; Vol. 11 (1), pp. e0148233. Date of Electronic Publication: 2016 Jan 29 (Print Publication: 2016).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transgenes*
Green Fluorescent Proteins/*genetics
Imaging, Three-Dimensional/*methods
Liver/*metabolism
Molecular Imaging/*methods
Plasmids/*pharmacokinetics
Animals ; Formaldehyde/chemistry ; Formamides/chemistry ; Gene Expression ; Genes, Reporter ; Green Fluorescent Proteins/metabolism ; Kidney/metabolism ; Kidney/ultrastructure ; Liver/ultrastructure ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Lung/metabolism ; Lung/ultrastructure ; Male ; Mice ; Octoxynol/chemistry ; Organ Specificity ; Plasmids/chemistry ; Plasmids/metabolism ; Polyethylene Glycols/chemistry ; Tissue Fixation ; Transfection ; Urea/chemistry
Czasopismo naukowe
Tytuł :
Effect of Metabolic Inhibitors on the Hepatic Disposition of 5-Fluorouracil after Application to the Rat Liver Surface.
Autorzy :
Shimokawa K; Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University.
Wakasugi K
Tomonaga R
Utsunomiya K
Miyamoto H
Fumoto S
Nishida K
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2016; Vol. 39 (3), pp. 361-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimetabolites, Antineoplastic/*pharmacokinetics
Fluorouracil/*pharmacokinetics
Liver/*metabolism
Pyridines/*pharmacology
Uridine/*pharmacology
Animals ; Antimetabolites, Antineoplastic/blood ; Fluorouracil/blood ; Liver/drug effects ; Male ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Evaluation of hypothermia on the in vitro metabolism and binding and in vivo disposition of midazolam in rats.
Autorzy :
Miyamoto H; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Matsueda S; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Moritsuka A; Department of Hospital Pharmacy, Nagasaki University Hospital, Japan.
Shimokawa K; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Hirata H; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Nakashima M; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Sasaki H; Department of Hospital Pharmacy, Nagasaki University Hospital, Japan.
Fumoto S; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Nishida K; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
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Źródło :
Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2015 Oct; Vol. 36 (7), pp. 481-9. Date of Electronic Publication: 2015 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*metabolism
Hypothermia/*blood
Liver/*metabolism
Midazolam/*blood
Animals ; Brain/drug effects ; Cells, Cultured ; Cytochrome P-450 CYP3A/metabolism ; Drug Evaluation, Preclinical/methods ; Liver/drug effects ; Male ; Midazolam/pharmacology ; Protein Binding/physiology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Loss of Gab1 adaptor protein in hepatocytes aggravates experimental liver fibrosis in mice.
Autorzy :
Kizu T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Yoshida Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Furuta K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Ogura S; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Egawa M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Chatani N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Hamano M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Takemura T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Ezaki H; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Kamada Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Nishida K; Laboratory for Homeostatic Network, RCAI, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan; and.
Nakaoka Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Kiso S; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan;
Takehara T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan; .
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Źródło :
American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2015 Apr 01; Vol. 308 (7), pp. G613-24. Date of Electronic Publication: 2015 Jan 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemical and Drug Induced Liver Injury/*metabolism
Hepatocytes/*metabolism
Liver/*metabolism
Liver Cirrhosis, Experimental/*metabolism
Phosphoproteins/*deficiency
Adaptor Proteins, Signal Transducing ; Animals ; Carbon Tetrachloride ; Cell Proliferation ; Cells, Cultured ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/genetics ; Chemical and Drug Induced Liver Injury/pathology ; Chemical and Drug Induced Liver Injury/prevention & control ; Chemokine CCL5/antagonists & inhibitors ; Chemokine CCL5/genetics ; Chemokine CCL5/metabolism ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Inflammation Mediators/metabolism ; Lipopolysaccharides/pharmacology ; Liver/drug effects ; Liver/pathology ; Liver Cirrhosis, Experimental/chemically induced ; Liver Cirrhosis, Experimental/genetics ; Liver Cirrhosis, Experimental/pathology ; Liver Cirrhosis, Experimental/prevention & control ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/metabolism ; Phosphoproteins/genetics ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Evaluation for effect of hypothermia on the disposition of 4-nitrophenol in rats by in-vitro metabolism study and rat liver perfusion system.
Autorzy :
Miyamoto H; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Matsueda S
Komori K
Fumoto S
Nakashima M
Yoshikawa N
Hirata H
Shimokawa K
Ohwaki Y
Nishida K
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Źródło :
The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2013 Oct; Vol. 65 (10), pp. 1536-40. Date of Electronic Publication: 2013 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Hypothermia, Induced*
Liver/*metabolism
Nitrophenols/*pharmacokinetics
Animals ; Body Temperature ; Cytochrome P-450 CYP2E1/metabolism ; In Vitro Techniques ; Liver/enzymology ; Male ; Perfusion ; Rats ; Rats, Wistar ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to liver surface in rats.
Autorzy :
Kodama Y; Graduate School of Biomedical Sciences, Nagasaki University Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan.
Horishita M
Fumoto S
Mine T
Miyamoto H
Yoshikawa N
Hirata H
Sasaki H
Nakamura J
Nishida K
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Źródło :
The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2012 Oct; Vol. 64 (10), pp. 1438-44. Date of Electronic Publication: 2012 Apr 17.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimetabolites, Antineoplastic/*pharmacokinetics
Excipients/*chemistry
Fluorouracil/*pharmacokinetics
Liver/*metabolism
Animals ; Antimetabolites, Antineoplastic/administration & dosage ; Carboxymethylcellulose Sodium/chemistry ; Delayed-Action Preparations ; Fluorouracil/administration & dosage ; Male ; Polyvinyl Alcohol/chemistry ; Rats ; Rats, Wistar ; Time Factors ; Viscosity
Czasopismo naukowe
Tytuł :
Evaluation of changes in hepatic disposition of phenolsulfonphthalein, indocyanine green and fluorescein isothiocyanate-dextran at low temperatures using a rat liver perfusion system.
Autorzy :
Miyamoto H; Graduate School of Biomedical Sciences, Nagasaki University Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan.
Miyake H
Yoshikawa N
Hirata H
Ohwaki Y
Fumoto S
Sasaki H
Nakamura J
Nishida K
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Źródło :
The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2012 Jun; Vol. 64 (6), pp. 848-54. Date of Electronic Publication: 2012 Feb 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cold Temperature*
Hypothermia, Induced*
Dextrans/*pharmacokinetics
Fluorescein-5-isothiocyanate/*analogs & derivatives
Indocyanine Green/*pharmacokinetics
Liver/*metabolism
Phenolsulfonphthalein/*pharmacokinetics
Animals ; Bile/metabolism ; Fluorescein-5-isothiocyanate/pharmacokinetics ; Inactivation, Metabolic ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Relationship between lipophilicity and absorption from the liver surface of paraben derivatives and antipyrine in rats.
Autorzy :
Nishida K; Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. />Kobayashi M
Miyamoto H
Yoshikawa N
Fumoto S
Sasaki H
Nakamura J
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Źródło :
The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2011 May; Vol. 63 (5), pp. 736-40. Date of Electronic Publication: 2011 Mar 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antipyrine/*metabolism
Lipids/*chemistry
Liver/*metabolism
Parabens/*metabolism
Animals ; Antipyrine/chemistry ; Biological Transport ; Male ; Molecular Weight ; Parabens/chemistry ; Rats ; Rats, Wistar ; Surface Properties
Czasopismo naukowe
Tytuł :
Safety of liver surface instillation of plasmid DNA in normal and carbon tetrachloride-induced hepatitis mice.
Autorzy :
Fumoto S; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. />Furukawa H
Nakamura J
Nishida K
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Źródło :
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques [J Pharm Pharm Sci] 2011; Vol. 14 (2), pp. 274-82.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemical and Drug Induced Liver Injury*
Carbon Tetrachloride/*pharmacology
Gene Transfer Techniques/*adverse effects
Hepatitis/*etiology
Liver/*metabolism
Plasmids/*administration & dosage
Animals ; Catheters ; Dose-Response Relationship, Drug ; Gene Expression/genetics ; Instillation, Drug ; Laparotomy/adverse effects ; Liver/drug effects ; Liver/surgery ; Luciferases, Firefly/genetics ; Male ; Mice ; Mice, Inbred Strains ; Plasmids/genetics ; Plasmids/pharmacology ; Transaminases/blood
Czasopismo naukowe
Tytuł :
[Development of drug delivery system by utilizing absorption from liver surface and its application].
Autorzy :
Nishida K; Division of Pharmaceutics, Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 854-8521, Japan.
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Źródło :
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan [Yakugaku Zasshi] 2009 Aug; Vol. 129 (8), pp. 925-32.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Pharmacokinetics*
Liver/*metabolism
Absorption ; Animals ; Antineoplastic Agents/pharmacokinetics ; Chemistry, Physical ; DNA/administration & dosage ; Drug Administration Routes ; Fluorouracil/pharmacokinetics ; Genetic Therapy ; Humans ; Molecular Weight ; Plasmids/administration & dosage ; Rats ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Correlation between voriconazole trough plasma concentration and hepatotoxicity in patients with different CYP2C19 genotypes.
Autorzy :
Matsumoto K; Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
Ikawa K
Abematsu K
Fukunaga N
Nishida K
Fukamizu T
Shimodozono Y
Morikawa N
Takeda Y
Yamada K
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Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2009 Jul; Vol. 34 (1), pp. 91-4. Date of Electronic Publication: 2009 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Polymorphism, Genetic*
Aryl Hydrocarbon Hydroxylases/*genetics
Liver/*drug effects
Plasma/*chemistry
Pyrimidines/*adverse effects
Triazoles/*adverse effects
Adult ; Aged ; Cytochrome P-450 CYP2C19 ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Voriconazole
Czasopismo naukowe
Tytuł :
Liver- and lobe-specific gene transfer following the continuous microinstillation of Plasmid DNA onto the liver surface in mice: effect of instillation speed.
Autorzy :
Fumoto S; Graduate School of Biomedical Sciences, Nagasaki University. />Tsuchimochi M
Nishi J
Ishii H
Kodama Y
Nakashima M
Sasaki H
Nakamura J
Nishida K
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2009 Jul; Vol. 32 (7), pp. 1298-302.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression*
Gene Transfer Techniques*
DNA/*administration & dosage
Liver/*metabolism
Plasmids/*administration & dosage
Animals ; DNA/genetics ; Genetic Vectors ; Instillation, Drug ; Luciferases, Firefly/genetics ; Male ; Mice ; Mice, Inbred Strains ; Organ Specificity ; Plasmids/genetics
Czasopismo naukowe
Tytuł :
Absorption and distribution characteristics of 5-fluorouracil (5-FU) after an application to the liver surface in rats in order to reduce systemic side effects.
Autorzy :
Kodama Y; Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Fumoto S
Nishi J
Nakashima M
Sasaki H
Nakamura J
Nishida K
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2008 May; Vol. 31 (5), pp. 1049-52.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimetabolites, Antineoplastic/*pharmacokinetics
Fluorouracil/*pharmacokinetics
Liver/*metabolism
Absorption ; Animals ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/adverse effects ; Diffusion Chambers, Culture ; Fluorouracil/administration & dosage ; Fluorouracil/adverse effects ; Injections, Intravenous ; Kidney/metabolism ; Male ; Rats ; Rats, Wistar ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.
Autorzy :
Hirayama R; Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Fumoto S
Nishida K
Nakashima M
Sasaki H
Nakamura J
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2005 Nov; Vol. 28 (11), pp. 2166-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*administration & dosage
DNA/*genetics
Liver/*physiology
Plasmids/*genetics
Transfection/*methods
Administration, Topical ; Animals ; Chemistry, Pharmaceutical ; DNA/chemistry ; Excipients ; Genes, Reporter/genetics ; Glucose/pharmacology ; Hydrogen-Ion Concentration ; Luciferases/genetics ; Male ; Mice ; Sodium Chloride/pharmacology ; Solutions
Czasopismo naukowe
Tytuł :
Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats: its implication for clinical use.
Autorzy :
Nishida K; Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki, 852-8521, Japan. />Fujiwara R
Kodama Y
Fumoto S
Mukai T
Nakashima M
Sasaki H
Nakamura J
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Źródło :
Pharmaceutical research [Pharm Res] 2005 Aug; Vol. 22 (8), pp. 1331-7. Date of Electronic Publication: 2005 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Antineoplastic Agents/*pharmacokinetics
Fluorouracil/*administration & dosage
Fluorouracil/*pharmacokinetics
Liver/*metabolism
Absorption ; Animals ; Antineoplastic Agents/therapeutic use ; Area Under Curve ; Drug Delivery Systems ; Fluorescein-5-isothiocyanate/pharmacokinetics ; Fluorescent Dyes/pharmacokinetics ; Fluorouracil/therapeutic use ; In Vitro Techniques ; Injections, Intraperitoneal ; Injections, Intravenous ; Organ Specificity ; Peritoneal Neoplasms/drug therapy ; Phenolsulfonphthalein/pharmacokinetics ; Rats
Czasopismo naukowe
Tytuł :
Diagnostic value of measuring liver volume for detecting occult hepatic metastases from colorectal or gastric cancer.
Autorzy :
Ishizawa T; First Department of Surgery, Tokyo Teishin Hospital, 2-14-23 Fujimi, Chiyoda-ku, Tokyo, 102-8798, Japan.
Yamamoto T
Nishida K
Tsukui H
Sekikawa T
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Źródło :
World journal of surgery [World J Surg] 2005 Jun; Vol. 29 (6), pp. 719-22.
Typ publikacji :
Journal Article
MeSH Terms :
Organ Size*
Adenocarcinoma/*diagnosis
Adenocarcinoma/*secondary
Liver/*pathology
Liver Neoplasms/*diagnosis
Liver Neoplasms/*secondary
Aged ; Body Surface Area ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Female ; Humans ; Liver/diagnostic imaging ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice.
Autorzy :
Hirayama R; Graduate School of Biomedical Sciences, Nagasaki University, Bunkyo-machi, Japan.
Nishida K
Fumoto S
Nakashima M
Sasaki H
Nakamura J
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Źródło :
Biological & pharmaceutical bulletin [Biol Pharm Bull] 2004 Oct; Vol. 27 (10), pp. 1697-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
DNA/*administration & dosage
Liver/*metabolism
Animals ; DNA/pharmacokinetics ; Gene Expression ; Luciferases/biosynthesis ; Luciferases/genetics ; Male ; Mice ; Plasmids
Czasopismo naukowe

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