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Tytuł:
Protein interaction networks characterizing the A549 cells Klotho transfected are associated with activated pro-apoptotic Bim and suppressed Wnt/β-catenin signaling pathway.
Autorzy:
Matsumoto M; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan.
Ogawa N; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan.
Fukuda T; Biosys Technologies, Inc, Tokyo, Tokyo, 153-8904, Japan.
Bando Y; Biosys Technologies, Inc, Tokyo, Tokyo, 153-8904, Japan.
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. .
Usuda J; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan. t.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 25; Vol. 14 (1), pp. 2130. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/genetics
Wnt Signaling Pathway*
Animals ; Humans ; Mice ; A549 Cells ; Bcl-2-Like Protein 11/genetics ; Protein Interaction Maps ; Proteome ; Proteomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transient asymptomatic pulmonary opacities in a patient with MET exon 14 skipping non-small cell lung cancer: A case report.
Autorzy:
Ikeo S; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yasuda N; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Sakai Y; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Hayashi Y; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Sokai A; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Iwata T; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Nishimura T; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
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Źródło:
Thoracic cancer [Thorac Cancer] 2023 Apr; Vol. 14 (10), pp. 958-960. Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans ; Proto-Oncogene Proteins c-met/genetics ; Proto-Oncogene Proteins c-met/metabolism ; Protein Kinase Inhibitors/adverse effects ; Exons ; Mutation
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Next-generation sequencing clarified why first-line treatment with osimertinib was ineffective in an autopsied case of EGFR-mutated lung squamous cell carcinoma.
Autorzy:
Nishimura T; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.; Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.
Fujiwara T; Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.; Department of Genomic Medicine, Mie University Hospital, Tsu, Japan.
Fujimoto H; Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.
Tarumi H; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Tsuji C; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Iwanaka S; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Sakakura Y; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Naito M; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Okugawa Y; Department of Genomic Medicine, Mie University Hospital, Tsu, Japan.
Yasuma T; Department of Immunology, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.
Gabazza EC; Department of Immunology, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.
Oomoto Y; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Kobayashi T; Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan.
Ibata H; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
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Źródło:
Thoracic cancer [Thorac Cancer] 2023 Mar; Vol. 14 (7), pp. 709-713. Date of Electronic Publication: 2023 Jan 29.
Typ publikacji:
Case Reports
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Carcinoma, Squamous Cell*/drug therapy
Carcinoma, Squamous Cell*/genetics
Carcinoma, Squamous Cell*/diagnosis
Male ; Humans ; Aged, 80 and over ; Autopsy ; Mutation ; ErbB Receptors/genetics ; Lung/pathology ; High-Throughput Nucleotide Sequencing ; Protein Kinase Inhibitors/therapeutic use
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primary Pulmonary Myxoid Sarcoma with EWSR1::ATF1 Fusion: A Case Report.
Autorzy:
Nishimura T; Division of Thoracic Surgery, 89662Ayabe City Hospital, Kyoto, Japan.
Ii T; Division of Thoracic Surgery, 89662Ayabe City Hospital, Kyoto, Japan.
Inamori O; Division of Diagnostic Pathology, 89662Ayabe City Hospital, Kyoto, Japan.
Konishi E; Department of Surgical Pathology, Graduate School of Medical Science, 12898Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yoshida A; Department of Diagnostic Pathology, 13874National Cancer Center, Tokyo, Japan.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2023 Feb; Vol. 31 (1), pp. 88-91. Date of Electronic Publication: 2022 Apr 24.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Sarcoma*/diagnosis
Sarcoma*/genetics
Sarcoma*/surgery
Male ; Humans ; Aged ; In Situ Hybridization, Fluorescence ; RNA-Binding Protein EWS/genetics ; Gene Fusion ; Oncogene Proteins, Fusion/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A randomized phase II study of docetaxel or pemetrexed with or without the continuation of gefitinib after disease progression in elderly patients with non-small cell lung cancer harboring EGFR mutations (JMTO LC12-01).
Autorzy:
Asami K; Asami Naika Clinic, Tokyo, Japan.
Ando M; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
Nishimura T; Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Japan.
Yokoi T; Department of Thoracic Oncology, Hyogo College of Medicine, Hyogo, Japan.
Tamura A; Department of Center for Pulmonary Diseases, Tokyo National Hospital, Tokyo, Japan.
Minato K; Department of Respiratory Medicine, Gunma Prefectural Cancer Center, Gunma, Japan.
Mori M; Department of Thoracic Oncology, National Hospital Organization Osaka Toneyama Medical Center, Osaka, Japan.
Ogushi F; Department of Respiratory Medicine, Kochi National Hospital, Kochi, Japan.
Yamamoto A; Department of Respiratory Medicine, Takamatsu Red Cross Hospital, Kagawa, Japan.
Yoshioka H; Department of Thoracic Oncology, Kansai Medical University Hospital, Osaka, Japan.
Kawahara M; Department of Respiratory Medicine, KKR Otemae Hospital, Osaka, Japan.
Atagi S; Department of Thoracic Oncology, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan.
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Źródło:
Thoracic cancer [Thorac Cancer] 2022 Jun; Vol. 13 (12), pp. 1827-1836. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols*/therapeutic use
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Aged ; Disease Progression ; Docetaxel/therapeutic use ; ErbB Receptors/genetics ; Gefitinib/therapeutic use ; Humans ; Mutation ; Pemetrexed/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protein co-expression network-based profiles revealed from laser-microdissected cancerous cells of lung squamous-cell carcinomas.
Autorzy:
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. t.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. t.
Fujii K; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Laboratory of Analytical Chemistry, Daiichi University of Pharmacy, Fukuoka, Fukuoka, 815-8511, Japan.
Nakamura H; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Naruki S; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Sakai H; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Kimura H; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Miyazawa T; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Takagi M; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Furuya N; Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Marko-Varga G; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, BMC D13, 221 84, Lund, Sweden.
Kato H; Tokyo Medical University, Tokyo, 160-0023, Japan.; International University of Health and Welfare, Tokyo, 107-8402, Japan.
Saji H; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Oct 12; Vol. 11 (1), pp. 20209. Date of Electronic Publication: 2021 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung/*metabolism
Carcinoma, Squamous Cell/*metabolism
Lung Neoplasms/*metabolism
Proteomics/*methods
Aged ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Laser Capture Microdissection ; Male ; Middle Aged ; Multivariate Analysis ; Protein Interaction Maps
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Second-line therapy with first- or second-generation tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer patients with T790M-negative or unidentified mutation.
Autorzy:
Nishimura T; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Okano T; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Naito M; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Iwanaka S; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Ohiwa A; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Sakakura Y; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Yasuma T; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Fujimoto H; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
D'Alessandro-Gabazza CN; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Oomoto Y; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
Kobayashi T; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Gabazza EC; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Ibata H; Department of Pulmonary Medicine, Mie Chuo Medical Center, Tsu, Japan.
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Źródło:
Thoracic cancer [Thorac Cancer] 2021 Apr; Vol. 12 (7), pp. 1067-1073. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; ErbB Receptors/metabolism ; Female ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Retrospective Studies ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A proteogenomic profile of early lung adenocarcinomas by protein co-expression network and genomic alteration analysis.
Autorzy:
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. t.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. t.
Nakamura H; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Tan KT; ACT Genomics Co., LTD., Taipei, 114, Taiwan.
Zhuo DW; ACT Genomics Co., LTD., Taipei, 114, Taiwan.
Fujii K; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Koizumi H; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Naruki S; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Takagi M; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Furuya N; Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Kato Y; Department of Thoracic Surgery, Kanto Central Hospital, Tokyo, 158-8531, Japan.
Chen SJ; ACT Genomics Co., LTD., Taipei, 114, Taiwan.
Kato H; Tokyo Medical University, Tokyo, 160-0023, Japan.; International University of Health and Welfare, Tokyo, 107-8402, Japan.
Saji H; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 12; Vol. 10 (1), pp. 13604. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Regulatory Networks*
Protein Interaction Maps*
Adenocarcinoma in Situ/*metabolism
Adenocarcinoma of Lung/*metabolism
Lung Neoplasms/*metabolism
Proteogenomics/*methods
Adenocarcinoma in Situ/genetics ; Adenocarcinoma of Lung/genetics ; Epithelial-Mesenchymal Transition ; Female ; Gene Dosage ; Humans ; Loss of Function Mutation ; Lung Neoplasms/genetics ; Male ; Middle Aged ; Neoplasm Invasiveness
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Disease-related cellular protein networks differentially affected under different EGFR mutations in lung adenocarcinoma.
Autorzy:
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. t.
Nakamura H; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Yachie A; The Systems Biology Institute, Tokyo, 141-0022, Japan.
Hase T; The Systems Biology Institute, Tokyo, 141-0022, Japan.
Fujii K; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Koizumi H; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Naruki S; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Takagi M; Department of Pathology, St. Marianna University Hospital, Kawasaki, Kanagawa, 216-8511, Japan.
Matsuoka Y; The Systems Biology Institute, Tokyo, 141-0022, Japan.
Furuya N; Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
Kato H; Tokyo Medical University, Tokyo, 160-0023, Japan.; International University of Health and Welfare, Tokyo, 107-8402, Japan.
Saji H; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 02; Vol. 10 (1), pp. 10881. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Genes, erbB-1*
Mutation, Missense*
Point Mutation*
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*genetics
Adenocarcinoma of Lung/metabolism ; Adult ; Aged ; Aged, 80 and over ; Datasets as Topic ; ErbB Receptors/genetics ; Female ; Gene Regulatory Networks ; Humans ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Neoplasm Proteins/metabolism ; Proteome ; Sequence Deletion ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of key modules and hub genes for small-cell lung carcinoma and large-cell neuroendocrine lung carcinoma by weighted gene co-expression network analysis of clinical tissue-proteomes.
Autorzy:
Nakamura H; Department of Chest Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.
Fujii K; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kanagawa, Japan.
Gupta V; The Systems Biology Institute, Tokyo, Japan.
Hata H; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Koizumu H; Department of Pathology, St. Marianna University Hospital, Kanagawa, Japan.
Hoshikawa M; Department of Pathology, St. Marianna University Hospital, Kanagawa, Japan.
Naruki S; Department of Pathology, St. Marianna University Hospital, Kanagawa, Japan.
Miyata Y; Corporate Technology Research and Development, NISSHA Co., Kyoto, Japan.
Takahashi I; Corporate Technology Research and Development, NISSHA Co., Kyoto, Japan.
Miyazawa T; Department of Chest Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.
Sakai H; Department of Chest Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.
Tsumoto K; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Takagi M; Department of Pathology, St. Marianna University Hospital, Kanagawa, Japan.
Saji H; Department of Chest Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kanagawa, Japan.
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Źródło:
PloS one [PLoS One] 2019 Jun 05; Vol. 14 (6), pp. e0217105. Date of Electronic Publication: 2019 Jun 05 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Profiling*
Gene Regulatory Networks*
Proteomics*
Carcinoma, Large Cell/*genetics
Carcinoma, Neuroendocrine/*genetics
Lung Neoplasms/*genetics
Small Cell Lung Carcinoma/*genetics
Aged ; Carcinoma, Large Cell/metabolism ; Carcinoma, Large Cell/pathology ; Carcinoma, Neuroendocrine/metabolism ; Carcinoma, Neuroendocrine/pathology ; Female ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Protein Interaction Mapping ; Small Cell Lung Carcinoma/metabolism ; Small Cell Lung Carcinoma/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Salvage surgery for primary lung cancer after chemotherapy in octogenarians.
Autorzy:
Hino H; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Nishimura T; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Usuki C; Department of Respiratory Medicine, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Sazuka M; Department of Respiratory Medicine, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Ito T; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Seki A; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Nitadori JI; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.; Department of Thoracic Surgery, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Yamada H; Department of Respiratory Medicine, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Arai T; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Yamamoto H; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Nakajima J; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.; Department of Thoracic Surgery, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
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Źródło:
Thoracic cancer [Thorac Cancer] 2017 May; Vol. 8 (3), pp. 271-274. Date of Electronic Publication: 2017 Feb 27.
Typ publikacji:
Case Reports
MeSH Terms:
Lymph Node Excision*
Carcinoma, Squamous Cell/*surgery
Lung Neoplasms/*surgery
Lymphatic Metastasis/*diagnostic imaging
Aged, 80 and over ; Carcinoma, Squamous Cell/diagnostic imaging ; Carcinoma, Squamous Cell/pathology ; Female ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Lymphatic Metastasis/pathology ; Positron-Emission Tomography ; Salvage Therapy
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A selected reaction monitoring mass spectrometric assessment of biomarker candidates diagnosing large-cell neuroendocrine lung carcinoma by the scaling method using endogenous references.
Autorzy:
Fukuda T; Biosys Technologies, Inc., Tokyo, Japan.
Nomura M; Department of Thoracic and Thyroid Surgery, Tokyo Medical University, Tokyo, Japan.
Kato Y; Department of Thoracic Surgery, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.
Tojo H; Department of Biophysics and Biochemistry, Osaka University Graduate School of Medicine, Osaka, Japan.
Fujii K; Department of Translational Medicine Informatics, St. Mariana University School of Medicine, Kawasaki, Japan.
Nagao T; Department of Clinical Pathology, Tokyo Medical University, Tokyo, Japan.
Bando Y; Biosys Technologies, Inc., Tokyo, Japan.
Fehniger TE; Center of Excellence in Biological and Medical Mass Spectrometry, Lund University, Lund, Sweden.; Clinical Protein Science & Imaging, Biomedical Center, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Marko-Varga G; Center of Excellence in Biological and Medical Mass Spectrometry, Lund University, Lund, Sweden.; Clinical Protein Science & Imaging, Biomedical Center, Department of Biomedical Engineering, Lund University, Lund, Sweden.
Nakamura H; Department of Translational Medicine Informatics, St. Mariana University School of Medicine, Kawasaki, Japan.; Department of Chest Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.
Kato H; Department of Thoracic and Thyroid Surgery, Tokyo Medical University, Tokyo, Japan.; Chest Surgery, Niizashiki Central General Hospital, Saitama, Japan.
Nishimura T; Department of Translational Medicine Informatics, St. Mariana University School of Medicine, Kawasaki, Japan.; Center of Excellence in Biological and Medical Mass Spectrometry, Lund University, Lund, Sweden.
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Źródło:
PloS one [PLoS One] 2017 Apr 27; Vol. 12 (4), pp. e0176219. Date of Electronic Publication: 2017 Apr 27 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor/*metabolism
Carcinoma, Large Cell/*diagnosis
Carcinoma, Neuroendocrine/*diagnosis
Lung Neoplasms/*diagnosis
Proteomics/*methods
Proteomics/*standards
Carcinoma, Large Cell/metabolism ; Carcinoma, Neuroendocrine/metabolism ; Humans ; Lung Neoplasms/metabolism ; Mass Spectrometry ; Reference Standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Oligo-recurrence predicts favorable prognosis of brain-only oligometastases in patients with non-small cell lung cancer treated with stereotactic radiosurgery or stereotactic radiotherapy: a multi-institutional study of 61 subjects.
Autorzy:
Niibe Y; Department of Radiology and Radiation Oncology, Kitasato University School of Medicine, 1-15-1, Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan. .; Department of Radiology, Toho University Omori Medical Center, 6-11-1, Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan. .
Nishimura T; Division of Radiation Oncology, Shizuoka Cancer Center, 1007, Monagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Inoue T; Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Kita 15-jo, Nishi 7-chome, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Karasawa K; Department of Radiation Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, Tokyo, 113-8677, Japan.
Shioyama Y; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.; Ion Beam Therapy Center, SAGA-HIMAT Foundation, 415, Harukoga-cho, Tosu, Saga, 841-0071, Japan.
Jingu K; Department of Radiation Oncology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Shirato H; Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Kita 15-jo, Nishi 7-chome, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2016 Aug 19; Vol. 16 (1), pp. 659. Date of Electronic Publication: 2016 Aug 19.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms/*radiotherapy
Brain Neoplasms/*secondary
Carcinoma, Non-Small-Cell Lung/*therapy
Cranial Irradiation/*methods
Lung Neoplasms/*therapy
Radiosurgery/*methods
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Prognosis ; Retrospective Studies ; Survival Analysis ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Re-irradiation for locoregionally recurrent tumors of the thorax: a single-institution, retrospective study.
Autorzy:
Sumita K; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan. .; Department of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakatashi, Osaka, 573-1010, Japan. .
Harada H; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Asakura H; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Ogawa H; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Onoe T; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Murayama S; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Nakamura S; Department of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakatashi, Osaka, 573-1010, Japan.
Tanigawa N; Department of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakatashi, Osaka, 573-1010, Japan.
Takahashi T; Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Nishimura T; Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
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Źródło:
Radiation oncology (London, England) [Radiat Oncol] 2016 Aug 02; Vol. 11, pp. 104. Date of Electronic Publication: 2016 Aug 02.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Re-Irradiation*
Lung Neoplasms/*radiotherapy
Neoplasm Recurrence, Local/*radiotherapy
Organs at Risk/*radiation effects
Thoracic Neoplasms/*radiotherapy
Adenocarcinoma/pathology ; Adenocarcinoma/radiotherapy ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/radiotherapy ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Prognosis ; Radiation Injuries/prevention & control ; Radiotherapy Dosage ; Retrospective Studies ; Small Cell Lung Carcinoma/pathology ; Small Cell Lung Carcinoma/radiotherapy ; Survival Rate ; Thoracic Neoplasms/pathology ; Trachea/radiation effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Experience of fluoroscopy-aided thoracoscopic resection of pulmonary nodule localised with Lipiodol in a child.
Autorzy:
Yamagami T; Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan. />Miura H
Yoshimatsu R
Tanaka O
Ono S
Iehara T
Hosoi H
Nishimura T
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Źródło:
Journal of medical imaging and radiation oncology [J Med Imaging Radiat Oncol] 2011 Aug; Vol. 55 (4), pp. 401-3.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Ethiodized Oil*
Thoracoscopy*
Hepatoblastoma/*diagnostic imaging
Hepatoblastoma/*surgery
Liver Neoplasms/*pathology
Lung Neoplasms/*diagnostic imaging
Lung Neoplasms/*surgery
Solitary Pulmonary Nodule/*diagnostic imaging
Solitary Pulmonary Nodule/*surgery
Tomography, X-Ray Computed/*methods
Child ; Contrast Media ; Fluoroscopy ; Hepatoblastoma/secondary ; Humans ; Lung Neoplasms/secondary ; Male ; Radiography, Interventional ; Solitary Pulmonary Nodule/secondary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Osteopontin is involved in migration of eosinophils in asthma.
Autorzy:
Takahashi A; First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Hokkaido, Japan.
Kurokawa M
Konno S
Ito K
Kon S
Ashino S
Nishimura T
Uede T
Hizawa N
Huang SK
Nishimura M
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2009 Aug; Vol. 39 (8), pp. 1152-9. Date of Electronic Publication: 2009 Apr 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Asthma/*immunology
Eosinophils/*immunology
Lung Neoplasms/*immunology
Osteopontin/*immunology
Adult ; Aged ; Animals ; Antibodies/immunology ; Antigen-Antibody Reactions ; Asthma/pathology ; Bronchial Hyperreactivity/immunology ; Bronchoalveolar Lavage Fluid/immunology ; Cell Movement/immunology ; Cytokines/analysis ; Disease Models, Animal ; Female ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Mice ; Mice, Inbred BALB C ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403).
Autorzy:
Tamura K; Outpatients Treatment Center, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. />Okamoto I
Kashii T
Negoro S
Hirashima T
Kudoh S
Ichinose Y
Ebi N
Shibata K
Nishimura T
Katakami N
Sawa T
Shimizu E
Fukuoka J
Satoh T
Fukuoka M
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Corporate Authors:
West Japan Thoracic Oncology Group
Źródło:
British journal of cancer [Br J Cancer] 2008 Mar 11; Vol. 98 (5), pp. 907-14. Date of Electronic Publication: 2008 Feb 19.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study
MeSH Terms:
Mutation*
Carcinoma, Non-Small-Cell Lung/*drug therapy
ErbB Receptors/*genetics
Lung Neoplasms/*drug therapy
Quinazolines/*therapeutic use
Adenocarcinoma, Bronchiolo-Alveolar/drug therapy ; Adenocarcinoma, Bronchiolo-Alveolar/genetics ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/genetics ; Disease Progression ; Female ; Gefitinib ; Gene Amplification ; Humans ; Lung Neoplasms/genetics ; Male ; Middle Aged ; Prospective Studies ; Quinazolines/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Percutaneous needle biopsy for small lung nodules beneath the rib under CT scan fluoroscopic guidance with gantry tilt.
Autorzy:
Yamagami T; Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-chyo, Kawaramachi-Hirokoji, Kamigyo, Kyoto, 602-8566, Japan. />Kato T
Iida S
Hirota T
Nishimura T
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Źródło:
Chest [Chest] 2004 Sep; Vol. 126 (3), pp. 744-7.
Typ publikacji:
Journal Article
MeSH Terms:
Ribs*
Biopsy, Needle/*methods
Fluoroscopy/*methods
Lung Neoplasms/*pathology
Solitary Pulmonary Nodule/*pathology
Surgery, Computer-Assisted/*methods
Tomography, X-Ray Computed/*methods
Diagnosis, Differential ; Humans ; Lung/pathology ; Lung Neoplasms/secondary ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 23

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