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Wyszukujesz frazę ""Nitric Oxide"" wg kryterium: Temat


Tytuł :
Nitric oxide effects on Rhodnius prolixus's immune responses, gut microbiota and Trypanosoma cruzi development.
Autorzy :
Batista KKDS; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Vieira CS; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Florentino EB; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Caruso KFB; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Teixeira PTP; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Moraes CDS; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil.
Genta FA; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil; Departamento de Entomologia Molecular, Instituto Nacional de Entomologia Molecular (INCT-EM), Rio de Janeiro, RJ, Brazil.
de Azambuja P; Departamento de Entomologia Molecular, Instituto Nacional de Entomologia Molecular (INCT-EM), Rio de Janeiro, RJ, Brazil; Programa de Pós-Graduação em Ciências e Biotecnologia, Universidade Federal Fluminense, Niteroi, RJ, Brazil.
de Castro DP; Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC/Fiocruz), Rio de Janeiro, RJ, Brazil; Departamento de Entomologia Molecular, Instituto Nacional de Entomologia Molecular (INCT-EM), Rio de Janeiro, RJ, Brazil. Electronic address: .
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Źródło :
Journal of insect physiology [J Insect Physiol] 2020 Oct; Vol. 126, pp. 104100. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nitric Oxide*/metabolism
Nitric Oxide*/pharmacology
Rhodnius*/immunology
Rhodnius*/microbiology
Rhodnius*/parasitology
Gastrointestinal Microbiome/*drug effects
Immune System/*drug effects
Trypanosoma cruzi/*drug effects
Animals ; Arginine/antagonists & inhibitors ; Arginine/pharmacology ; Catalase/drug effects ; Catalase/metabolism ; Gastrointestinal Tract/drug effects ; Gastrointestinal Tract/microbiology ; Gene Expression/drug effects ; Genes, Insect ; Hemolymph/drug effects ; Hemolymph/immunology ; Hemolymph/metabolism ; Immunity, Humoral/drug effects ; Insect Vectors/immunology ; Insect Vectors/microbiology ; Insect Vectors/parasitology ; Monophenol Monooxygenase/drug effects ; Monophenol Monooxygenase/metabolism ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide Synthase/genetics ; Nitric Oxide Synthase/metabolism
Czasopismo naukowe
Tytuł :
Modulation of peroxynitrite produced via mitochondrial nitric oxide synthesis during Ca and succinate-induced oxidative stress in cardiac isolated mitochondria.
Autorzy :
Gerdes HJ; Anesthesiology Research Division, Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Yang M; Anesthesiology Research Division, Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Heisner JS; Anesthesiology Research Division, Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Camara AKS; Anesthesiology Research Division, Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.
Stowe DF; Anesthesiology Research Division, Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA; Research Service, Zablocki Veterans Affairs Medical Center, Milwaukee, WI, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2020 Dec 01; Vol. 1861 (12), pp. 148290. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Calcium/*pharmacology
Mitochondria, Heart/*metabolism
Nitric Oxide/*biosynthesis
Oxidative Stress/*drug effects
Peroxynitrous Acid/*metabolism
Succinic Acid/*pharmacology
Animals ; Electron Transport/drug effects ; Free Radical Scavengers/metabolism ; Guinea Pigs ; Hydrogen Peroxide/metabolism ; Isoenzymes/metabolism ; Isoenzymes/ultrastructure ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria, Heart/drug effects ; Mitochondria, Heart/ultrastructure ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase/ultrastructure ; Spectrometry, Fluorescence ; Stress, Physiological/drug effects ; Superoxide Dismutase/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Modulating the Bioactivity of Nitric Oxide as a Therapeutic Strategy in Cardiac Surgery.
Autorzy :
Pisarenko O; National Medical Research Center for Cardiology, Institute of Experimental Cardiology, Moscow, Russian Federation. Electronic address: .
Studneva I; National Medical Research Center for Cardiology, Institute of Experimental Cardiology, Moscow, Russian Federation.
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Źródło :
The Journal of surgical research [J Surg Res] 2021 Jan; Vol. 257, pp. 178-188. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cardiotonic Agents/*pharmacology
Heart Arrest, Induced/*adverse effects
Myocardial Reperfusion Injury/*prevention & control
Nitric Oxide/*metabolism
Animals ; Cardiotonic Agents/therapeutic use ; Disease Models, Animal ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/pathology ; Gap Junctions/drug effects ; Heart/drug effects ; Humans ; Ion Channels/metabolism ; MicroRNAs/therapeutic use ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/pathology ; Myocardium/pathology ; Nitric Oxide/agonists ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Stem Cell Transplantation/methods
Czasopismo naukowe
Tytuł :
Synergistic effects of nitric oxide and silicon on promoting plant growth, oxidative stress tolerance and reduction of arsenic uptake in Brassica juncea.
Autorzy :
Ahmad A; Guangdong Key Laboratory for New Technology Research of Vegetables/ Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Khan WU; College of Earth and Environmental Sciences, University of the Punjab, Lahore, Pakistan.
Ali Shah A; Department of Botany, University of Narowal, Pakistan.
Yasin NA; SSG, RO-II, University of the Punjab, Lahore, Pakistan. Electronic address: .
Naz S; Department of Biotechnology, Lahore College for Women University, Pakistan.
Ali A; Department of Botany, University of Sargodha, Pakistan.
Tahir A; Department of Biotechnology, Lahore College for Women University, Pakistan.
Iram Batool A; Department of Zoology, University of Sargodha, Pakistan.
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Źródło :
Chemosphere [Chemosphere] 2021 Jan; Vol. 262, pp. 128384. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Arsenic/*metabolism
Mustard Plant/*physiology
Nitric Oxide/*chemistry
Silicon/*chemistry
Soil Pollutants/*metabolism
Antioxidants/metabolism ; Arsenic/toxicity ; Ascorbate Peroxidases/metabolism ; Glutathione/metabolism ; Glutathione Reductase/metabolism ; Hydrogen Peroxide/metabolism ; Malondialdehyde/metabolism ; Mustard Plant/metabolism ; Nitric Oxide Donors/metabolism ; Nitric Oxide Donors/pharmacology ; Nitroprusside/pharmacology ; Oxidative Stress/drug effects ; Seedlings/drug effects ; Soil Pollutants/toxicity ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Autorzy :
Elbatreek MH; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Department of Pharmacology and Toxicology, School of Pharmacy, Zagazig University, Zagazig, Egypt.
Sadegh S; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Anastasi E; School of Computing, Newcastle University, Newcastle, United Kingdom.
Guney E; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Research Programme on Biomedical Informatics, The Hospital del Mar Medical Research Institute and Pompeu Fabra University, Barcelona, Spain.
Nogales C; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
Kacprowski T; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.; Division of Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Brunswick, Germany.
Hassan AA; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
Teubner A; Central Animal Facility, CPV, Maastricht University, Maastricht, the Netherlands.
Huang PH; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.; Department of Critical Care Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Hsu CY; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan.; Taipei Heart Institute, Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Schiffers PMH; Department of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Janssen GM; Department of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Kleikers PWM; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
Wipat A; School of Computing, Newcastle University, Newcastle, United Kingdom.
Baumbach J; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.; Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark.
De Mey JGR; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
Schmidt HHHW; Department of Pharmacology and Personalised Medicine, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
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Źródło :
PLoS biology [PLoS Biol] 2020 Nov 10; Vol. 18 (11), pp. e3000885. Date of Electronic Publication: 2020 Nov 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypertension/*physiopathology
NADPH Oxidase 5/*genetics
Nitric Oxide/*metabolism
Adult ; Age Factors ; Aged ; Animals ; Endothelial Cells ; Endothelium, Vascular ; Female ; Gene Knock-In Techniques/methods ; Humans ; Hypertension/genetics ; Hypertension/metabolism ; Male ; Membrane Proteins/genetics ; Mice ; Middle Aged ; NADPH Oxidase 5/metabolism ; NADPH Oxidases/genetics ; NADPH Oxidases/metabolism ; Nitric Oxide/genetics ; Nitric Oxide Synthase/genetics ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
A new mechanism for the sex differences in angiotensin II-induced hypertension: the role of macula densa NOS1β-mediated tubuloglomerular feedback.
Autorzy :
Zhang J; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Qu L; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Wei J; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Jiang S; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Xu L; College of Public Health, University of South Florida, Tampa, Florida.
Wang L; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Cheng F; Department of Pharmaceutical Science, College of Pharmacy, University of South Florida, Tampa, Florida.
Jiang K; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Buggs J; Advanced Organ Disease and Transplantation Institute, Tampa General Hospital, Tampa, Florida.
Liu R; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Nov 01; Vol. 319 (5), pp. F908-F919. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Sex Characteristics*
Hypertension/*metabolism
Kidney Tubules/*drug effects
Nitric Oxide Synthase/*metabolism
Angiotensin II/pharmacology ; Animals ; Feedback ; Female ; Glomerular Filtration Rate/drug effects ; Hypertension/chemically induced ; Kidney Cortex/metabolism ; Kidney Glomerulus/drug effects ; Kidney Glomerulus/metabolism ; Kidney Tubules/metabolism ; Male ; Mice, Knockout ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type I/metabolism
Czasopismo naukowe
Tytuł :
Interplay of the red blood cell and vascular endothelial nitric oxide synthase system to combat cardiac complications of anemia.
Autorzy :
Daiber A; Center for Cardiology, Cardiology I, University Medical Center Mainz, Geb. 605, Langenbeckstr. 1, 55131, Mainz, Germany. .; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany. .
Münzel T; Center for Cardiology, Cardiology I, University Medical Center Mainz, Geb. 605, Langenbeckstr. 1, 55131, Mainz, Germany. .; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany. .
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Źródło :
Basic research in cardiology [Basic Res Cardiol] 2020 Jun 12; Vol. 115 (4), pp. 44. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Anemia*
Nitric Oxide Synthase*
Endothelium, Vascular ; Erythrocytes ; Humans ; Nitric Oxide Synthase Type III
Raport
Tytuł :
Hypertension is associated with blunted NO-mediated leg vasodilator responsiveness that is reversed by high-intensity training in postmenopausal women.
Autorzy :
Gunnarsson TP; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Ehlers TS; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Baasch-Skytte T; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Lund AP; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Tamariz-Ellemann A; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Gliemann L; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Nyberg M; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Bangsbo J; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2020 Dec 01; Vol. 319 (6), pp. R712-R723. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
High-Intensity Interval Training*
Postmenopause*
Vasodilation*/drug effects
Hypertension/*therapy
Lower Extremity/*blood supply
Nitric Oxide/*metabolism
Acetylcholine/administration & dosage ; Age Factors ; Aged ; Female ; Humans ; Hypertension/metabolism ; Hypertension/physiopathology ; Middle Aged ; Nitric Oxide Donors/administration & dosage ; Nitroprusside/administration & dosage ; Oxidative Stress ; Sex Factors ; Time Factors ; Treatment Outcome ; Vasodilator Agents/administration & dosage
Czasopismo naukowe
Tytuł :
Methylene blue may have a role in the treatment of COVID-19.
Autorzy :
Ghahestani SM; Tehran University of Medical Sciences (TUMS), Tehran, Iran. Electronic address: .
Shahab E; Semnan University of Medical Sciences(SemUMS), Semnan, Iran.
Karimi S; Alborz University of Medical Sciences (AbzUMS), Alborz, Iran.
Madani MH; Shahid Beheshti University of Medical Sciences(SBMU), Tehran, Iran.
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Źródło :
Medical hypotheses [Med Hypotheses] 2020 Nov; Vol. 144, pp. 110163. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*drug therapy
Methylene Blue/*pharmacology
Nitric Oxide Synthase/*antagonists & inhibitors
Angiotensin-Converting Enzyme 2/metabolism ; Aprotinin/pharmacology ; Bradykinin/analogs & derivatives ; Bradykinin/metabolism ; Bradykinin/pharmacology ; Cytokines/metabolism ; Humans ; Kininogens/metabolism ; Models, Theoretical ; Nitric Oxide/metabolism ; Peptides/pharmacology ; Renin-Angiotensin System
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Nitric oxide plays a crucial role in midgut immunity under microsporidian infection in Antheraea pernyi.
Autorzy :
Liu W; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China; Sericultural Research Institute of Liaoning Province, Fengcheng 118100, PR China.
Wang Y; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China. Electronic address: .
Leng Z; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China.
Wang Q; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China.
Duan X; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China.
Luo Y; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China.
Jiang Y; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China.
Qin L; College of Bioscience and Biotechnology, Shenyang Agricultural University, Liaoning Engineering and Technology Research Center for Insect Resource, Shenyang 110866, PR China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Oct; Vol. 126, pp. 65-72. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrointestinal Tract/*immunology
Microsporidiosis/*veterinary
Moths/*immunology
Nitric Oxide/*metabolism
Nosema/*immunology
Animals ; Antimicrobial Cationic Peptides/metabolism ; Arthropod Proteins/antagonists & inhibitors ; Arthropod Proteins/metabolism ; Down-Regulation ; Gastrointestinal Tract/drug effects ; Gastrointestinal Tract/metabolism ; Gastrointestinal Tract/microbiology ; Immunity, Humoral/drug effects ; Immunity, Mucosal/drug effects ; Microsporidiosis/immunology ; Moths/enzymology ; Moths/microbiology ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitric Oxide Synthase/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Spatio-Temporal Analysis
Czasopismo naukowe
Tytuł :
Mutual inter-regulation between iNOS and TGF-β1: Possible molecular and cellular mechanisms of iNOS in wound healing.
Autorzy :
Abd El-Aleem SA; Department of Histology and Cell Biology, Minia Faculty of Medicine, Minia University, Minia, Egypt. Electronic address: .
Mohammed HH; Department of Histology and Cell Biology, Minia Faculty of Medicine, Minia University, Minia, Egypt.
Saber EA; Department of Histology and Cell Biology, Minia Faculty of Medicine, Minia University, Minia, Egypt; Deraya University, New Minia, Egypt.
Embaby AS; Department of Histology and Cell Biology, Beni-Suef University, Egypt.
Djouhri L; Department of Physiology, College of Medicine (QU Health), Qatar University, P.O. Box 2713, Doha, Qatar.
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Oct 01; Vol. 1866 (10), pp. 165850. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Nitric Oxide Synthase Type II/*metabolism
Transforming Growth Factor beta1/*metabolism
Wound Healing/*physiology
Animals ; Arginase/metabolism ; Collagen/metabolism ; Disease Models, Animal ; Fibroblasts/metabolism ; Guanidines/pharmacology ; Humans ; Male ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type II/drug effects ; Nitric Oxide Synthase Type II/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Skin/metabolism ; Skin/pathology
Czasopismo naukowe
Tytuł :
Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19.
Autorzy :
Adusumilli NC; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Zhang D; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY, USA.
Friedman JM; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: .
Friedman AJ; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA. Electronic address: .
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Źródło :
Nitric oxide : biology and chemistry [Nitric Oxide] 2020 Oct 01; Vol. 103, pp. 4-8. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Coronavirus Infections/*prevention & control
Nitric Oxide/*therapeutic use
Pandemics/*prevention & control
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*prevention & control
Administration, Inhalation ; COVID-19 ; Humans ; Nitric Oxide/administration & dosage ; Nitric Oxide Donors/therapeutic use ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Synchronous detection of vascular tension and nitric oxide release in pulmonary artery: A combined application of confocal wire myograph with confocal laser scanning microscopy.
Autorzy :
Zhuang XL; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.; Department of Pathology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.
Zhu ZL; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Zhu JL; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Lai SM; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Gui LX; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Lin MJ; Department of Physiology & Pathophysiology, The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
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Źródło :
Vascular [Vascular] 2020 Oct; Vol. 28 (5), pp. 619-628. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Microscopy, Confocal*
Myography*
Vasodilation*/drug effects
Endothelium, Vascular/*metabolism
Nitric Oxide/*metabolism
Pulmonary Artery/*metabolism
Acetylcholine/pharmacology ; Animals ; Dose-Response Relationship, Drug ; Endothelium, Vascular/drug effects ; Enzyme Inhibitors/pharmacology ; Male ; Mice, Inbred ICR ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitric Oxide Synthase/metabolism ; Pulmonary Artery/drug effects ; Time Factors ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł :
Active modulation of human erythrocyte mechanics.
Autorzy :
Kuck L; Biorheology Research Laboratory, Griffith University Gold Coast, Southport, Queensland, Australia.
Peart JN; School of Medical Science, Griffith University Gold Coast, Southport, Queensland, Australia.
Simmonds MJ; Biorheology Research Laboratory, Griffith University Gold Coast, Southport, Queensland, Australia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Aug 01; Vol. 319 (2), pp. C250-C257. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes/*metabolism
Ion Channels/*genetics
Mechanotransduction, Cellular/*genetics
Nitric Oxide Synthase/*genetics
Calcium/metabolism ; Cell Membrane/enzymology ; Cell Membrane/genetics ; Enzyme Activation/genetics ; Erythrocytes/enzymology ; Gene Expression Regulation, Enzymologic/genetics ; Humans ; Ion Channels/blood ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism
Czasopismo naukowe
Tytuł :
Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro.
Autorzy :
Akaberi D; Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden.
Krambrich J; Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden.
Ling J; Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden.
Luni C; Department of Microbiology and Tumour and Cell Biology (MTC), Karolinska Institute, Solna, Sweden.
Hedenstierna G; Department of Medical Sciences, Section of Clinical Physiology, Uppsala University, Uppsala, Sweden.
Järhult JD; Department of Medical Sciences, Zoonosis Science Center, Uppsala University, Uppsala, Sweden.
Lennerstrand J; Department of Medical Sciences, Section of Clinical Microbiology, Uppsala University, Uppsala, Sweden.
Lundkvist Å; Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden. Electronic address: .
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Źródło :
Redox biology [Redox Biol] 2020 Oct; Vol. 37, pp. 101734. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
COVID-19/*drug therapy
Nitric Oxide Donors/*pharmacology
S-Nitroso-N-Acetylpenicillamine/*pharmacology
SARS-CoV-2/*drug effects
Virus Replication/*drug effects
Animals ; Catalytic Domain/drug effects ; Chlorocebus aethiops ; Coronavirus 3C Proteases/antagonists & inhibitors ; Coronavirus 3C Proteases/metabolism ; Humans ; Models, Molecular ; Nitric Oxide/pharmacology ; SARS-CoV-2/enzymology ; SARS-CoV-2/physiology ; Vero Cells ; Viral Protease Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
High dose folic acid is a potential treatment for pulmonary hypertension, including when associated with COVID-19 pneumonia.
Autorzy :
Wiltshire E; Paediatrics and Child Health, University of Otago Wellington, PO Box 7343, Wellington South 6242, New Zealand; Department of Paediatrics and Child Health, Capital and Coast District Health Board, Wellington 7902, New Zealand. Electronic address: .
Peña AS; Robinson Research Institute and Discipline of Paediatrics, University of Adelaide, North Adelaide, South Australia 5006, Australia; Endocrinology and Diabetes Centre, Women's and Children's Hospital, North Adelaide, South Australia 5006, Australia.
MacKenzie K; Department of Paediatrics, University of Otago Christchurch, Christchurch, New Zealand; Department of Paediatrics, Canterbury District Health Board, Christchurch, New Zealand.
Shaw G; Department of Anaesthesia, University of Otago Christchurch, Christchurch, New Zealand; Department of Intensive Care, Canterbury District Health Board, Christchurch, New Zealand.
Couper J; Robinson Research Institute and Discipline of Paediatrics, University of Adelaide, North Adelaide, South Australia 5006, Australia; Endocrinology and Diabetes Centre, Women's and Children's Hospital, North Adelaide, South Australia 5006, Australia.
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Źródło :
Medical hypotheses [Med Hypotheses] 2020 Oct; Vol. 143, pp. 110142. Date of Electronic Publication: 2020 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus*
Pandemics*
Coronavirus Infections/*complications
Folic Acid/*therapeutic use
Hypertension, Pulmonary/*drug therapy
Nitric Oxide/*metabolism
Pneumonia, Viral/*complications
Administration, Inhalation ; Animals ; COVID-19 ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiology ; Enzyme Activation/drug effects ; Folic Acid/administration & dosage ; Folic Acid/pharmacology ; Humans ; Hypertension, Pulmonary/complications ; Hypoxia/drug therapy ; Hypoxia/etiology ; Mice ; Nitric Oxide/administration & dosage ; Nitric Oxide/therapeutic use ; Nitric Oxide Synthase Type III/drug effects ; SARS-CoV-2 ; Tachyphylaxis
Czasopismo naukowe
Tytuł :
miR-369-3p modulates inducible nitric oxide synthase and is involved in regulation of chronic inflammatory response.
Autorzy :
Scalavino V; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Liso M; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Cavalcanti E; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Gigante I; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Lippolis A; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Mastronardi M; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Chieppa M; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy.
Serino G; National Institute of Gastroenterology 'S. de Bellis', Research Hospital, Via Turi, 27, Castellana Grotte, 70013, Bari, Italy. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 29; Vol. 10 (1), pp. 15942. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*genetics
MicroRNAs/*genetics
Nitric Oxide Synthase Type II/*metabolism
Animals ; CCAAT-Enhancer-Binding Protein-beta/metabolism ; Cytokines/metabolism ; Dendritic Cells/metabolism ; Dendritic Cells/physiology ; Inflammation/metabolism ; Interleukin-12/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/metabolism ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/genetics ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Identification of New Nitric Oxide-Donating Peptides with Dual Biofilm Eradication and Antibacterial Activities for Intervention of Device-Related Infections.
Autorzy :
Fei Y; Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, China.; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Wu J; Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, China.
An HW; Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Yuquan Road, Beijing 100049, China.
Zhu K; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Peng B; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Cai J; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Zhang Y; Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, China.
Li LL; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Wang H; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beiyitiao No.11, Haidian District, Beijing, 100190, China.
Huang Z; Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9127-9135. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antimicrobial Cationic Peptides/*chemistry
Biofilms/*drug effects
Nitric Oxide Donors/*chemistry
Amino Acid Sequence ; Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/therapeutic use ; Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Cationic Peptides/therapeutic use ; Cephalosporins/pharmacology ; Escherichia coli/physiology ; Hemolysis/drug effects ; Injections, Subcutaneous ; Mice ; Nitric Oxide/metabolism ; Nitric Oxide Donors/pharmacology ; Nitric Oxide Donors/therapeutic use ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/pathology ; Staphylococcus aureus/physiology
Czasopismo naukowe
Tytuł :
In vitro anti-inflammatory activities of naucleoffieine H as a natural alkaloid from Nauclea officinalis Pierrc ex Pitard, through inhibition of the iNOS pathway in LPS-activated RAW 264.7 macrophages.
Autorzy :
Song S; Department of Rehabilitation Medicine, Yantai Yu-Huang-Ding Hospital, Yantai, Shandong, P. R. China.
Liu P; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
Wang L; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
Li D; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
Fan H; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
Chen D; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
Zhao F; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, School of Pharmacy, Yantai University, Yantai, Shandong, P. R. China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Sep; Vol. 34 (18), pp. 2694-2697. Date of Electronic Publication: 2019 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*isolation & purification
Anti-Inflammatory Agents/*isolation & purification
Macrophages/*metabolism
Nitric Oxide Synthase Type II/*antagonists & inhibitors
Rubiaceae/*chemistry
Alkaloids/pharmacology ; Animals ; Anti-Inflammatory Agents/pharmacology ; Cyclooxygenase 2/metabolism ; Lipopolysaccharides ; Macrophages/drug effects ; Mice ; NF-kappa B/metabolism ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase Type II/metabolism ; RAW 264.7 Cells ; Rubiaceae/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Sex-differences in cholinergic, nicotinic, and β-adrenergic cutaneous vasodilation: Roles of nitric oxide synthase, cyclooxygenase, and K channels.
Autorzy :
Fujii N; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada; Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan. Electronic address: .
McGarr GW; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada.
Ghassa R; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada.
Schmidt MD; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada.
McCormick JJ; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada.
Nishiyasu T; Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
Kenny GP; Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
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Źródło :
Microvascular research [Microvasc Res] 2020 Sep; Vol. 131, pp. 104030. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Vasodilation*/drug effects
Blood Vessels/*enzymology
Nitric Oxide Synthase/*metabolism
Potassium Channels/*metabolism
Prostaglandin-Endoperoxide Synthases/*metabolism
Receptors, Adrenergic, beta/*metabolism
Receptors, Cholinergic/*metabolism
Skin/*blood supply
Adrenergic beta-Agonists/pharmacology ; Adult ; Blood Vessels/drug effects ; Cholinergic Agonists/pharmacology ; Cyclooxygenase Inhibitors/pharmacology ; Female ; Forearm ; Humans ; Male ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/antagonists & inhibitors ; Potassium Channel Blockers/pharmacology ; Potassium Channels/drug effects ; Receptors, Nicotinic/metabolism ; Sex Factors ; Signal Transduction ; Young Adult
Czasopismo naukowe

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