Temat: "Nitric Oxide Synthase Type II" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: New natural pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) and iNOS inhibitors identified from Penicillium polonicum through in vitro and in vivo studies.
Autorzy:: Paramita Pal P; Department of Pharmacy, Birla Institute of Technology & Science - Pilani, Hyderabad Campus, Jawahar Nagar, Shameerpet, Hyderabad 500078, Telangana State, India.
Sajeli Begum A; Department of Pharmacy, Birla Institute of Technology & Science - Pilani, Hyderabad Campus, Jawahar Nagar, Shameerpet, Hyderabad 500078, Telangana State, India. Electronic address: .
Ameer Basha S; Department of Plant Pathology, Professor Jeyashanker Telangana State Agricultural University, Rajendra Nagar, Hyderabad 500030, Telangana State, India.
Araya H; School of Agriculture, Meiji University, Kawasaki, Kanagawa 214-8571, Japan.
Fujimoto Y; School of Agriculture, Meiji University, Kawasaki, Kanagawa 214-8571, Japan.; Pokaż więcej
Źródło:: International immunopharmacology [Int Immunopharmacol] 2023 Apr; Vol. 117, pp. 109940. Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:: Journal Article
MeSH Terms:: Nitric Oxide Synthase Type II*/antagonists & inhibitors
Cytokines*/biosynthesis
Penicillium*/chemistry
RAW 264.7 Cells ; Protein Biosynthesis/drug effects ; Enzyme Inhibitors/isolation & purification ; Enzyme Inhibitors/pharmacology ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Animals ; Mice ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology
SCR Organism:: Penicillium polonicum

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Skocz do pozycji: 2.

Tytuł:: Inducible nitric oxide synthase deficiency promotes murine-β-coronavirus induced demyelination.
Autorzy:: Kamble M; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, 741246, India.
Saadi F; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, 741246, India.
Kumar S; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, 741246, India.
Saha B; National Centre for Cell Science, Ganeshkhind, Pune, India.
Das Sarma J; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, 741246, India. .; Department of Ophthalmology, University of Pennsylvania Scheie Eye Institute, Philadelphia, PA, 19104, USA. .; Pokaż więcej
Źródło:: Virology journal [Virol J] 2023 Mar 25; Vol. 20 (1), pp. 51. Date of Electronic Publication: 2023 Mar 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Demyelinating Diseases*/pathology
Demyelinating Diseases*/virology
Murine hepatitis virus*/metabolism
Nitric Oxide Synthase Type II*/genetics
Nitric Oxide Synthase Type II*/metabolism
Coronavirus Infections*/pathology
Animals ; Mice ; Membrane Glycoproteins ; Mice, Inbred C57BL ; Neuroinflammatory Diseases ; Receptors, Immunologic

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Skocz do pozycji: 3.

Tytuł:: Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson's disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy.
Autorzy:: Kim J; Department of Neurodegenerative Diseases Group, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea.
Han JY; Laboratory Animal Center, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea.
Lee Y; Cognitive Science Research Group, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea.
Kim K; Research Strategy Office, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea.
Choi YP; Laboratory Animal Center, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea. .
Chae S; Neurovescular Unit Research Group, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea. .
Hoe HS; Department of Neurodegenerative Diseases Group, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41062, South Korea. .; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu, 42988, South Korea. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2023 Jan 16; Vol. 16 (1), pp. 7. Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nitric Oxide Synthase Type II*/genetics
Parkinson Disease*/genetics
Parkinson Disease*/pathology
Synucleinopathies*
Animals ; Mice ; alpha-Synuclein/metabolism ; Disease Models, Animal ; Mice, Transgenic ; Neuroinflammatory Diseases

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Skocz do pozycji: 4.

Tytuł:: iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation.
Autorzy:: Guo Y; Division of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wen J; Division of Cardiology, West China Guang'an Hospital of Sichan University, Guang'an 638500, China.
He A; Division of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Qu C; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Peng Y; Division of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Luo S; Division of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .
Wang X; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .; Pokaż więcej
Źródło:: Journal of advanced research [J Adv Res] 2023 Jan; Vol. 43, pp. 175-186. Date of Electronic Publication: 2022 Mar 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Heart Failure*/metabolism
Mitochondria*/metabolism
Mitochondria*/pathology
Nitric Oxide Synthase Type II*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Animals ; Mice ; Oxidative Stress ; Stroke Volume/physiology

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Skocz do pozycji: 5.

Tytuł:: Decreasing effects of protein kinase inhibitors on the expression of NOS2 and inflammatory cytokines and on phagocytosis in rat peritoneal macrophages is partly related to repolarization.
Autorzy:: Hrabák A; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary. Electronic address: .
Bögel G; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary.
Murányi J; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary.
Tamási V; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary.
Németh K; Department of Genetics, Cell, and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest H-1083, Hungary.
Szokol B; Vichem Chemie Research Ltd., Viola u. 2., Veszprém H-8200, Hungary.
Kukor Z; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary.
Kardon T; Department of Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, Budapest H-1094, Hungary.
Őrfi L; Vichem Chemie Research Ltd., Viola u. 2., Veszprém H-8200, Hungary; Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes E. u. 9., Budapest H-1092, Hungary.; Pokaż więcej
Źródło:: Molecular immunology [Mol Immunol] 2023 Jan; Vol. 153, pp. 10-24. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cytokines*/metabolism
Macrophages, Peritoneal*/metabolism
Nitric Oxide Synthase Type II*/metabolism
Protein Kinase Inhibitors*/pharmacology
Animals ; Humans ; Rats ; Janus Kinases ; Phagocytosis

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Skocz do pozycji: 6.

Tytuł:: The Inhibition of the Inducible Nitric Oxide Synthase Enhances the DPSC Mineralization under LPS-Induced Inflammation.
Autorzy:: Cataldi A; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.
Amoroso R; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.
di Giacomo V; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.
Zara S; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.
Maccallini C; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.
Gallorini M; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 23; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:: Journal Article
MeSH Terms:: Inflammation*
Nitric Oxide*
Nitric Oxide Synthase Type II*/antagonists & inhibitors
Stem Cells*/cytology
Humans ; Amidines ; Dental Pulp/cytology ; Calcification, Physiologic

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Skocz do pozycji: 7.

Tytuł:: LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages.
Autorzy:: Wei Z; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Institute of Biomolecular Design & Discovery, Yale University, West Haven, CT, USA.
Oh J; Institute of Biomolecular Design & Discovery, Yale University, West Haven, CT, USA.; Department of Chemistry, Yale University, New Haven, CT, USA.
Flavell RA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. .; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA. .
Crawford JM; Institute of Biomolecular Design & Discovery, Yale University, West Haven, CT, USA. .; Department of Chemistry, Yale University, New Haven, CT, USA. .; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA. .; Pokaż więcej
Źródło:: Nature [Nature] 2022 Sep; Vol. 609 (7926), pp. 348-353. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Inflammation*/enzymology
Inflammation*/immunology
Inflammation*/metabolism
Intracellular Signaling Peptides and Proteins*/metabolism
Macrophages*/immunology
Macrophages*/metabolism
Nitric Oxide Synthase Type II*/metabolism
Animals ; Arthritis/immunology ; Arthritis/metabolism ; Citrulline/metabolism ; Cyanates/metabolism ; Humans ; Inflammatory Bowel Diseases/immunology ; Inflammatory Bowel Diseases/metabolism ; Mice ; Ornithine/metabolism ; Ornithine Decarboxylase/metabolism ; Polyamines/metabolism ; Salmonella typhimurium/immunology

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Skocz do pozycji: 8.

Tytuł:: Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont.
Autorzy:: Kopelyanskiy D; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Desponds C; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Prevel F; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Rossi M; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Migliorini R; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Snäkä T; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Eren RO; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Center for Molecular Medicine, University of Cologne, Cologne, Germany.
Claudinot S; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Lye LF; Department of Molecular Microbiology, School of Medicine, Washington University, St. Louis, MO, United States.
Pasparakis M; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Center for Molecular Medicine, University of Cologne, Cologne, Germany.
Beverley SM; Department of Molecular Microbiology, School of Medicine, Washington University, St. Louis, MO, United States.
Fasel N; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.; Pokaż więcej
Źródło:: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Aug 12; Vol. 12, pp. 944819. Date of Electronic Publication: 2022 Aug 12 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Leishmania*
Leishmania guyanensis*/virology
Nitric Oxide Synthase Type II*/metabolism
Animals ; Cytokines ; Humans ; Interleukin-17 ; Leishmaniavirus ; Mice ; NF-kappa B ; Nitric Oxide ; Toll-Like Receptor 3
SCR Organism:: Leishmania RNA virus 1

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Skocz do pozycji: 9.

Tytuł:: NOS2/miR-493-5p Signaling Regulates in the LPS-Induced Inflammatory Response in the RAW264.7 Cells.
Autorzy:: Li X; Clinical Laboratory, The Third People's Hospital of Kunming, Kunming, China.
Yang Y; Department of Hepatology, The Third People's Hospital of Kunming, Kunming, China.
Lu N; Department of Respiratory Medicine, The Third People's Hospital of Kunming, Kunming, China.
Luo F; Clinical Laboratory, The Third People's Hospital of Kunming, Kunming, China.
Fan R; School of Public Health, Dali University, Dali, China.
Peng N; School of Life Science and Technology and School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, 710049, China. .; Pokaż więcej
Źródło:: Biochemical genetics [Biochem Genet] 2023 Jun; Vol. 61 (3), pp. 1097-1112. Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Lipopolysaccharides/pharmacology ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Signal Transduction ; Cytokines/metabolism ; Computational Biology/methods

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Skocz do pozycji: 10.

Tytuł:: Antioxidative and Anti-Inflammatory Activities of Rosebud Extracts of Newly Crossbred Roses.
Autorzy:: Wang C; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kim IJ; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.
Seong HR; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.
Noh CH; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.
Park S; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.
Kim TM; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.
Jeong HS; Department of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kim KY; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kim ST; Gumi Floriculture Research Institute, Gyeongsanbuk-do Agricultural Research & Extension Services, Gumi 39102, Republic of Korea.
Yuk HG; Department of Food Science and Biotechnology, Korea National University of Transportation, Jeungpyeong 27909, Republic of Korea.
Kwon SC; Department of Food Science and Biotechnology, Korea National University of Transportation, Jeungpyeong 27909, Republic of Korea.
Choi EK; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.
Kim YB; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.; Central Research Institute, Designed Cells Co., Ltd., Cheongju 28576, Republic of Korea.; Pokaż więcej
Źródło:: Nutrients [Nutrients] 2023 May 19; Vol. 15 (10). Date of Electronic Publication: 2023 May 19.
Typ publikacji:: Journal Article
MeSH Terms:: Plant Extracts*/therapeutic use
Antioxidants*/therapeutic use
Humans ; Cyclooxygenase 2/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Inflammation/drug therapy ; Inflammation/chemically induced ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Dexamethasone/adverse effects ; Nitric Oxide/metabolism ; Lipopolysaccharides/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Echinacea Polyphenols Inhibit NLRP3-Dependent Pyroptosis, Apoptosis, and Necroptosis via Suppressing NO Production during Lipopolysaccharide-Induced Acute Lung Injury.
Autorzy:: Guo J; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Luo Y; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Zuo J; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Teng J; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shen B; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Liu X; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.; Pokaż więcej
Źródło:: Journal of agricultural and food chemistry [J Agric Food Chem] 2023 May 17; Vol. 71 (19), pp. 7289-7298. Date of Electronic Publication: 2023 May 08.
Typ publikacji:: Journal Article
MeSH Terms:: Echinacea*
Acute Lung Injury*/chemically induced
Acute Lung Injury*/drug therapy
Acute Lung Injury*/genetics
Pyroptosis ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Lipopolysaccharides/adverse effects ; Nitric Oxide/metabolism ; Polyphenols ; Necroptosis ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Inflammasomes/metabolism ; Apoptosis

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Skocz do pozycji: 12.

Tytuł:: Interferon-gamma is quintessential for NOS2 and COX2 expression in ER breast tumors that lead to poor outcome.
Autorzy:: Cheng RYS; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Ridnour LA; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Wink AL; Optical Microscopy and Analysis Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. for the National Cancer Institute, Frederick, MD, USA.
Gonzalez AL; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Femino EL; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Rittscher H; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Somasundaram V; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Heinz WF; Optical Microscopy and Analysis Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. for the National Cancer Institute, Frederick, MD, USA.
Coutinho L; Center for Translational Research in Oncology, ICESP/HC, Faculdade de Medicina da Universidade de São Paulo; and Comprehensive Center for Precision Oncology, Universidade de São Paulo, São Paulo, SP, Brazil.
Rangel MC; Center for Translational Research in Oncology, ICESP/HC, Faculdade de Medicina da Universidade de São Paulo; and Comprehensive Center for Precision Oncology, Universidade de São Paulo, São Paulo, SP, Brazil.
Edmondson EF; Molecular Histopathology Laboratories, Leidos Biomedical Research Inc. for NCI, Frederick, MD, USA.
Butcher D; Molecular Histopathology Laboratories, Leidos Biomedical Research Inc. for NCI, Frederick, MD, USA.
Kinders RJ; Office of the Director, Division of Cancer Treatment and Diagnosis, NCI, Frederick, MD, USA.
Li X; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
Wong STC; Systems Medicine and Bioengineering Department, Houston Methodist Neal Cancer Center, Houston Methodist Hospital and Weill Cornell Medicine, Houston, TX, USA.
McVicar DW; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Anderson SK; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Pore M; Imaging Mass Cytometry Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Hewitt SM; Laboratory of Pathology CCR, NCI, NIH, Bethesda, MD, USA.
Billiar TR; Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, 15213, USA.
Glynn SA; Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, University of Galway, Galway, Ireland.
Chang JC; Mary and Ron Neal Cancer Center, Houston Methodist Hospital and Weill Cornell Medicine, Houston, TX, USA.
Lockett SJ; Optical Microscopy and Analysis Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. for the National Cancer Institute, Frederick, MD, USA.
Ambs S; Laboratory of Human Carcinogenesis, CCR, NCI, NIH, Bethesda, MD, USA.
Wink DA; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA. .; Pokaż więcej
Źródło:: Cell death & disease [Cell Death Dis] 2023 May 11; Vol. 14 (5), pp. 319. Date of Electronic Publication: 2023 May 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Triple Negative Breast Neoplasms*/pathology
Mammary Neoplasms, Animal*
Animals ; Humans ; Interferon-gamma/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; CD8-Positive T-Lymphocytes ; Cell Line, Tumor ; Tumor Microenvironment ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism

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Skocz do pozycji: 13.

Tytuł:: Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation.
Autorzy:: Kim GO; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 41566, Republic of Korea.
Park DH; Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea.
Bae JS; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 41566, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*/metabolism
Lipopolysaccharides*/toxicity
Humans ; Mice ; Animals ; Cyclooxygenase 2/metabolism ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; NF-E2-Related Factor 2/metabolism ; Endothelial Cells/metabolism ; Inflammation/drug therapy ; Heme Oxygenase-1/metabolism ; Nitric Oxide/metabolism

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Skocz do pozycji: 14.

Tytuł:: iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.
Autorzy:: Shen J; Department of Parasitology and Key Laboratory of Tropical Disease Control (SYSU), Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, P.R. China.; Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou, Guangdong, P.R. China.
Yu SF; Clinical Research Institute, The First People's Hospital of Foshan, Foshan, P.R. China.
Peng M; Department of Parasitology and Key Laboratory of Tropical Disease Control (SYSU), Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, P.R. China.; Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou, Guangdong, P.R. China.
Lai DH; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, P.R. China.
Hide G; Ecosystems and Environment Research Centre and Biomedical Research Centre, School of Science, Engineering and Environment, University of Salford, Salford, United Kingdom.
Wu ZD; Department of Parasitology and Key Laboratory of Tropical Disease Control (SYSU), Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, P.R. China.; Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou, Guangdong, P.R. China.
Lun ZR; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, P.R. China.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 May 18; Vol. 16 (5), pp. e0010403. Date of Electronic Publication: 2022 May 18 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nitric Oxide Synthase Type II*/genetics
Nitric Oxide Synthase Type II*/metabolism
Nitric Oxide Synthase Type II*/physiology
Schistosoma japonicum*
Schistosomiasis japonica*/enzymology
Schistosomiasis japonica*/immunology
Th1 Cells*/immunology
Th2 Cells*/immunology
Animals ; Chemokines/metabolism ; Cytokines/metabolism ; Nitric Oxide/metabolism ; Rats

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Skocz do pozycji: 15.

Tytuł:: Angiotensin-(1-7) improves diabetes mellitus-induced erectile dysfunction in rats by regulating nitric oxide synthase levels.
Autorzy:: Xu Y; Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China; First Department of Endocrinology, Tangshan Gongren Hospital, Tangshan City, Hebei Province, China.
Zhang F; Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Li C; Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Hao H; Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Hao Y; Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China. Electronic address: .; Pokaż więcej
Źródło:: Peptides [Peptides] 2022 May; Vol. 151, pp. 170765. Date of Electronic Publication: 2022 Feb 15.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/enzymology
Diabetes Mellitus, Experimental*/metabolism
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/enzymology
Diabetes Mellitus, Type 2*/metabolism
Erectile Dysfunction*/drug therapy
Erectile Dysfunction*/enzymology
Erectile Dysfunction*/metabolism
Nitric Oxide Synthase Type II*/genetics
Nitric Oxide Synthase Type II*/metabolism
Peptide Fragments*/pharmacology
Angiotensin I ; Animals ; Calcium/metabolism ; Humans ; Male ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats

Czasopismo naukowe

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Szczegóły

Skocz do pozycji: 16.

Tytuł:: Attenuation of COX-2 enzyme by modulating H 2 O 2 -mediated NF-κB signaling pathway by monoamine oxidase inhibitor (MAOI): a further study on the reprofiling of MAOI in acute inflammation.
Autorzy:: Sur D; Division of Pharmacology, Guru Nanak Institute of Pharmaceutical Science and Technology, Panihati, Kolkata, 700114, India. .; Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata, 700109, India. .
Mondal C; TCG Life Science (Chembiotek) Pvt. Ltd, Sector V, Salt Lake Electronic Complex, Kolkata, 700091, India.
Balaraman AK; Faculty of Pharmacy, MAHSA University, Bandar Saujana Putra, 42610, Jenjarom, Selangor, Malaysia.
Haldar PK; Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India.
Maji HS; Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata, 700109, India.
Bala A; Division of Life Sciences, Institute of Advanced Study in Science and Technology, an Autonomous Institute under the Department of Science and Technology (Govt. of India) Vigyan Path, Guwahati, Assam, 781035, India. asisbala_.; Pokaż więcej
Źródło:: Inflammopharmacology [Inflammopharmacology] 2023 Jun; Vol. 31 (3), pp. 1305-1317. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*/metabolism
Hydrogen Peroxide*/metabolism
Mice ; Humans ; Animals ; Cyclooxygenase 2/metabolism ; Monoamine Oxidase Inhibitors/adverse effects ; Signal Transduction ; Carrageenan/pharmacology ; Inflammation/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Edema/metabolism ; Monoamine Oxidase/metabolism ; Monoamine Oxidase/pharmacology ; Monoamine Oxidase/therapeutic use ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism

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Szczegóły

Skocz do pozycji: 17.

Tytuł:: Crosstalk between phytochemicals and inflammatory signaling pathways.
Autorzy:: Prasad S; Department of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Kumar V; Department of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Singh C; Department of Pharmaceutical Sciences, School of Pharmacy, H.N.B. Garhwal University, Srinagar, Garhwal, 246174, Uttarakhand, India.
Singh A; Department of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India. .; Affiliated to IK Gujral Punjab Technical University, Jalandhar, Punjab, 144603, India. .; Pokaż więcej
Źródło:: Inflammopharmacology [Inflammopharmacology] 2023 Jun; Vol. 31 (3), pp. 1117-1147. Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Phosphatidylinositol 3-Kinases*/metabolism
Signal Transduction*
Humans ; NF-kappa B/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Phytochemicals/pharmacology ; Lipopolysaccharides/pharmacology ; Nitric Oxide Synthase Type II/metabolism ; Cyclooxygenase 2/metabolism

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Skocz do pozycji: 18.

Tytuł:: Anti-inflammatory steroids from the stems of Solanum nigrum L.
Autorzy:: Deng J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Wang L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Jin Q; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Zeng J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Xu J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Engineering Research Center for Lead Compounds & Drug Discovery, Guangzhou, 510006, China.
He X; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Engineering Research Center for Lead Compounds & Drug Discovery, Guangzhou, 510006, China. Electronic address: .
Wang Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Engineering Research Center for Lead Compounds & Drug Discovery, Guangzhou, 510006, China. Electronic address: .; Pokaż więcej
Źródło:: Phytochemistry [Phytochemistry] 2023 Jun; Vol. 210, pp. 113667. Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:: Journal Article
MeSH Terms:: Solanum nigrum*/chemistry
Animals ; Mice ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/metabolism ; Macrophages/metabolism ; NF-kappa B/metabolism ; Steroids/chemistry ; Lipopolysaccharides/pharmacology ; Nitric Oxide ; Nitric Oxide Synthase Type II/metabolism ; RAW 264.7 Cells

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Szczegóły

Skocz do pozycji: 19.

Tytuł:: Effect of nitric oxide synthase gene polymorphism on inflammatory response in patients with chronic obstructive pulmonary disease.
Autorzy:: Liao C; Department of Pulmonary and Critical Care Medicine, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China.
Li Z; Department of Pulmonary and Critical Care Medicine, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China.
Li F; Department of Pulmonary and Critical Care Medicine, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China. Electronic address: fengsenli_.
Xu D; Department of Pulmonary and Critical Care Medicine, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China.
Jing J; Department of Pulmonary and Critical Care Medicine, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China.; Pokaż więcej
Źródło:: Cytokine [Cytokine] 2023 Jun; Vol. 166, pp. 156207. Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:: Journal Article
MeSH Terms:: Pulmonary Disease, Chronic Obstructive*/pathology
Humans ; Nitric Oxide Synthase ; Polymorphism, Genetic ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type II/genetics ; Smoking ; Nitric Oxide

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Szczegóły

Skocz do pozycji: 20.

Tytuł:: Arginine concentration in arterial vs venous blood in a bleomycin-induced lung inflammation model in mice.
Autorzy:: Tepic S; Hepius Biotech AG, Zurich, Switzerland.
Arens D; AO Research Institute, Davos, Switzerland.
Buchholz T; AO Research Institute, Davos, Switzerland.
Nehrbass D; AO Research Institute, Davos, Switzerland.
Cvetkovic O; Hepius Biotech AG, Zurich, Switzerland.
Stoddart MJ; AO Research Institute, Davos, Switzerland.
Richards RG; AO Research Institute, Davos, Switzerland.
Zeiter S; AO Research Institute, Davos, Switzerland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 May 12; Vol. 18 (5), pp. e0285770. Date of Electronic Publication: 2023 May 12 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*/pathology
Pneumonia*/pathology
Mice ; Humans ; Animals ; Arginine/metabolism ; Bleomycin/toxicity ; Endothelial Cells/metabolism ; Citrulline/metabolism ; Pandemics ; Lung/pathology ; Nitric Oxide Synthase Type II/metabolism ; Nitric Oxide/metabolism

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