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Tytuł:
Design, synthesis, and biological evaluation of novel NO-releasing 4-chromanone derivatives as potential vasodilator agents.
Autorzy:
Shi H; Department of Chemistry, College of Science, Shanghai University, Shanghai, China.; School of Medicine, Shanghai University, Shanghai, China.
Xiong L; School of Medicine, Shanghai University, Shanghai, China.
Zhu C; School of Medicine, Shanghai University, Shanghai, China.
Wang J; Department of Pharmacy, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Li Y; School of Medicine, Shanghai University, Shanghai, China.
Luo Y; School of Medicine, Shanghai University, Shanghai, China.
Wang T; School of Medicine, Shanghai University, Shanghai, China.
Zhang C; Department of Chemistry, College of Science, Shanghai University, Shanghai, China.; School of Medicine, Shanghai University, Shanghai, China.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Feb; Vol. 101 (2), pp. 408-421. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Vasodilator Agents*/pharmacology
Vasodilator Agents*/chemistry
Nitric Oxide*/metabolism
Nitric Oxide Donors/chemistry ; Antihypertensive Agents/pharmacology ; Antihypertensive Agents/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Erbu Zhuyu decoction improves endometrial angiogenesis via uterine natural killer cells and the PI3K/Akt/eNOS pathway a mouse model of embryo implantation dysfunction.
Autorzy:
Shen M; Department of Gynecology, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Liu Y; Department of Gynecology, Beijing University of Chinese Medicine Affiliated Dongzhimen Hospital, Beijing, China.
Ma X; Department of Gynecology, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Zhu Q; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2023 Jan; Vol. 89 (1), pp. e13634. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Nitric Oxide Synthase Type III*/metabolism
Pregnancy ; Female ; Mice ; Animals ; Phosphatidylinositol 3-Kinase/metabolism ; Phosphatidylinositol 3-Kinase/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Embryo Implantation ; Nitric Oxide/metabolism ; Disease Models, Animal ; Killer Cells, Natural/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nitric Oxide Synthase inhibition counteracts the stress-induced DNA methyltransferase 3b expression in the hippocampus of rats.
Autorzy:
de Sousa Maciel I; School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto - SP, Brazil.
Sales AJ; School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto - SP, Brazil.
Casarotto PC; Neuroscience Center, HiLIFE, University of Helsinki, Finland.
Castrén E; Neuroscience Center, HiLIFE, University of Helsinki, Finland.
Biojone C; Neuroscience Center, HiLIFE, University of Helsinki, Finland.
Joca SRL; Department of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto -SP, Brazil.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 May; Vol. 55 (9-10), pp. 2421-2434. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hippocampus*/metabolism
Nitric Oxide Synthase*
Animals ; DNA (Cytosine-5-)-Methyltransferases/genetics ; Enzyme Inhibitors/pharmacology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type I ; RNA, Messenger/metabolism ; Rats ; Receptors, N-Methyl-D-Aspartate/metabolism ; Stress, Physiological ; DNA Methyltransferase 3B
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liraglutide improves obesity-induced renal injury by alleviating uncoupling of the glomerular VEGF-NO axis in obese mice.
Autorzy:
Li K; Department of Nephrology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Sun J; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Huang N; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Ma Y; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Han F; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Liu Y; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Hou N; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.
Sun X; Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, China.; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Dec; Vol. 47 (12), pp. 1978-1984. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Liraglutide*
Nitric Oxide*
Vascular Endothelial Growth Factor A*
Animals ; Kidney Glomerulus ; Male ; Mice ; Mice, Obese ; Nitric Oxide Synthase Type III
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nitric oxide regulates the firing rate of neuronal subtypes in the guinea pig ventral cochlear nucleus.
Autorzy:
Hockley A; Medical Research Council Institute of Hearing Research, School of Medicine, University of Nottingham, Nottingham, UK.; School of Life Sciences, University of Nottingham, Nottingham, UK.; Department of Otolaryngology, Kresge Hearing Research Institute, University of Michigan, Ann Arbor, MI, USA.
Berger JI; Medical Research Council Institute of Hearing Research, School of Medicine, University of Nottingham, Nottingham, UK.; Department of Neurosurgery, University of Iowa, Iowa City, IA, USA.
Smith PA; School of Life Sciences, University of Nottingham, Nottingham, UK.
Palmer AR; Medical Research Council Institute of Hearing Research, School of Medicine, University of Nottingham, Nottingham, UK.; Hearing Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Wallace MN; Medical Research Council Institute of Hearing Research, School of Medicine, University of Nottingham, Nottingham, UK.; Hearing Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2020 Feb; Vol. 51 (4), pp. 963-983. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cochlear Nucleus*
Nitric Oxide*
Animals ; Enzyme Inhibitors/pharmacology ; Guinea Pigs ; NG-Nitroarginine Methyl Ester/pharmacology ; Neurons ; Nitric Oxide Donors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy.
Autorzy:
Jin, Guiyuan (AUTHOR)
Yao, Xiaoying (AUTHOR)
Liu, Dong (AUTHOR)
Zhang, Juan (AUTHOR)
Zhang, Xiaobei (AUTHOR)
Yang, Yonghong (AUTHOR)
Bi, Yanzhen (AUTHOR)
Zhang, Hui (AUTHOR)
Dong, Guanjun (AUTHOR)
Tang, Huixin (AUTHOR)
Cheng, Shumin (AUTHOR)
Hong, Feng (AUTHOR)
Si, Meng (AUTHOR)
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Źródło:
Immunity, Inflammation & Disease. Dec2023, Vol. 11 Issue 12, p1-16. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Situ Forming of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Gold Yarn‐Dynamos.
Autorzy:
Chiang, Min‐Ren (AUTHOR)
Lin, Ya‐Hui (AUTHOR)
Zhao, Wei‐Jie (AUTHOR)
Liu, Hsiu‐Ching (AUTHOR)
Hsu, Ru‐Siou (AUTHOR)
Chou, Tsu‐Chin (AUTHOR)
Lu, Tsai‐Te (AUTHOR)
Lee, I‐Chi (AUTHOR)
Liao, Lun‐De (AUTHOR)
Chiou, Shih‐Hwa (AUTHOR)
Chu, Li‐An (AUTHOR)
Hu, Shang‐Hsiu (AUTHOR)
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Źródło:
Advanced Science. 11/24/2023, Vol. 10 Issue 33, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Testosterone positively regulates functional responses and nitric oxide expression in the isolated human corpus cavernosum.
Autorzy:
Gur S; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.; Department of Pharmacology, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
Alzweri L; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.; Division of Urology, Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Yilmaz-Oral D; Department of Pharmacology, Faculty of Pharmacy, Cukurova University, Adana, Turkey.
Kaya-Sezginer E; Department of Biochemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
Abdel-Mageed AB; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.
Dick B; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.
Sikka SC; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.
Volkan Oztekin C; Department of Urology, Faculty of Medicine, University of Kyrenia, Turkish Republic of North Cyprus, Girne, Mersin 10, Turkey.
Hellstrom WJG; Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.
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Źródło:
Andrology [Andrology] 2020 Nov; Vol. 8 (6), pp. 1824-1833. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclic GMP/*metabolism
Nitric Oxide/*biosynthesis
Penis/*metabolism
Testosterone/*pharmacology
Cyclic Nucleotide Phosphodiesterases, Type 5/analysis ; Erectile Dysfunction/blood ; Hormone Replacement Therapy ; Humans ; Male ; Middle Aged ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type I/analysis ; Nitric Oxide Synthase Type III/analysis ; Penile Induration/blood ; Sildenafil Citrate/pharmacology ; Testosterone/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nitric oxide-soluble guanylyl cyclase pathway as a contributor to age-related memory impairment in Drosophila.
Autorzy:
Tonoki A; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Nagai S; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Yu Z; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Yue T; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Lyu S; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Hou X; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Onuki K; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Yabana K; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Takahashi H; Medical Mycology Research Center, Chiba University, Chiba, Japan.
Itoh M; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
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Źródło:
Aging cell [Aging Cell] 2022 Sep; Vol. 21 (9), pp. e13691. Date of Electronic Publication: 2022 Aug 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drosophila*/metabolism
Nitric Oxide*/metabolism
Animals ; Guanylate Cyclase/genetics ; Guanylate Cyclase/metabolism ; Receptors, Cytoplasmic and Nuclear/genetics ; Soluble Guanylyl Cyclase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats.
Autorzy:
Lee GH; Non-Clinical Evaluation Center, Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Korea.
Hoang TH; Non-Clinical Evaluation Center, Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Korea.
Jung ES; Clinical Trial Center for Functional Foods (CTCF2), Jeonbuk National University Hospital, Jeonju, Korea.
Jung SJ; Clinical Trial Center for Functional Foods (CTCF2), Jeonbuk National University Hospital, Jeonju, Korea.
Han SK; Department of Oral Physiology, School of Dentistry & Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Korea.
Chung MJ; Department of Pathology, Jeonbuk National University Medical School, Jeonju, Korea.
Chae SW; Clinical Trial Center for Functional Foods (CTCF2), Jeonbuk National University Hospital, Jeonju, Korea.
Chae HJ; Non-Clinical Evaluation Center, Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Korea.; School of Pharmacy, Jeonbuk National University, Jeonju, Korea.; Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.
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Źródło:
Aging cell [Aging Cell] 2020 Dec; Vol. 19 (12), pp. e13279. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging/*physiology
Anthocyanins/*pharmacology
Endothelium, Vascular/*drug effects
Endothelium, Vascular/*physiopathology
Nitric Oxide Synthase Type III/*metabolism
Animals ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/physiopathology ; Cellular Senescence/drug effects ; Human Umbilical Vein Endothelial Cells ; Humans ; Male ; Morus/chemistry ; Nitric Oxide/biosynthesis ; Oxidative Stress/drug effects ; Plant Extracts/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sirtuin 1/metabolism ; Uncoupling Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Low androgen status inhibits erectile function by inducing eNOS uncoupling in rat corpus cavernosum.
Autorzy:
Xiong W; Department of Urology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Kong X; Department of Urology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jiang J; Department of Thyroid Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yang Z; Department of Pathology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jiang R; Department of Urology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nephropathy Clinical Medical Research Center of Sichuan Province, Luzhou, China.
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Źródło:
Andrology [Andrology] 2020 Nov; Vol. 8 (6), pp. 1875-1883. Date of Electronic Publication: 2020 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Erectile Dysfunction/*physiopathology
Nitric Oxide Synthase Type III/*metabolism
Penile Erection/*physiology
Penis/*blood supply
Testosterone/*blood
Animals ; Arterial Pressure/physiology ; Castration ; Cyclic GMP/metabolism ; Erectile Dysfunction/therapy ; Male ; NADPH Oxidase 2/blood ; Nitric Oxide/blood ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Testosterone/therapeutic use ; Tetrahydrofolate Dehydrogenase/blood ; Tyrosine/analogs & derivatives ; Tyrosine/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of nitric oxide on apoptosis and voltage-gated calcium channels in human cardiac myofibroblasts.
Autorzy:
Bae H; Department of Physiology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
Kim T; Department of Internal Medicine, College of Medicine, Chung-Ang University Hospital, Seoul, Republic of Korea.
Lim I; Department of Physiology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Jan; Vol. 47 (1), pp. 16-26. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Calcium Channels/*metabolism
Myofibroblasts/*metabolism
Nitric Oxide/*metabolism
Apoptosis/drug effects ; Carbazoles/pharmacology ; Cells, Cultured ; Cyclic GMP/analogs & derivatives ; Cyclic GMP/metabolism ; Cyclic GMP-Dependent Protein Kinases/metabolism ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Guanylate Cyclase/metabolism ; Humans ; Myofibroblasts/drug effects ; Nitric Oxide Donors/metabolism ; Pyrroles/pharmacology ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacological inhibition of the F 1 -ATPase/P2Y 1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation.
Autorzy:
Cabou C; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.; Department of Human Physiology, Faculty of Pharmacy, University Paul Sabatier, Toulouse, France.
Honorato P; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Briceño L; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Ghezali L; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
Duparc T; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
León M; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Combes G; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
Frayssinhes L; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
Fournel A; UMR 1220, IRSD, INSERM, INRA, ENVT, European Associated Laboratory NeuroMicrobiota (INSERM/UCL), University of Toulouse, Toulouse, France.
Abot A; UMR 1220, IRSD, INSERM, INRA, ENVT, European Associated Laboratory NeuroMicrobiota (INSERM/UCL), University of Toulouse, Toulouse, France.
Masri B; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
Parada N; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Aguilera V; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Aguayo C; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.; Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan, Chile.
Knauf C; UMR 1220, IRSD, INSERM, INRA, ENVT, European Associated Laboratory NeuroMicrobiota (INSERM/UCL), University of Toulouse, Toulouse, France.
González M; Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan, Chile.; Vascular Physiology Laboratory, Department of Physiology, Faculty of Biological Sciences, and Department of Obstetrics and Gynecology, Faculty of Medicine, Universidad de Concepción, Concepción, Chile.
Radojkovic C; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Universidad de Concepción, Concepción, Chile.
Martinez LO; INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, University of Toulouse, Paul Sabatier University, Toulouse, France.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2019 Jul; Vol. 226 (3), pp. e13268. Date of Electronic Publication: 2019 Apr 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*/physiology
Apolipoprotein A-I/*metabolism
Endothelium/*metabolism
Nitric Oxide Synthase Type III/*metabolism
Adenosine Diphosphate/metabolism ; Animals ; Female ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Nitric Oxide/metabolism ; Pregnancy ; Proton-Translocating ATPases/metabolism ; Receptors, Purinergic P2Y1/metabolism ; Vasodilation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Perivascular adipose tissue and microvascular endothelial dysfunction in obese mice: Beneficial effects of aerobic exercise in adiponectin receptor (AdipoR1) and peNOS Ser1177 .
Autorzy:
Sousa AS; Laboratory of Vascular Biology, Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.
Sponton ACS; Laboratory of Vascular Biology, Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.
Delbin MA; Laboratory of Vascular Biology, Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2021 Oct; Vol. 48 (10), pp. 1430-1440. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Physical Conditioning, Animal*
Endothelium, Vascular/*pathology
Nitric Oxide/*metabolism
Nitric Oxide Synthase Type III/*metabolism
Receptors, Adiponectin/*metabolism
Receptors, Leptin/*metabolism
Serine/*chemistry
Animals ; Aorta/metabolism ; Aorta/pathology ; Diet, High-Fat ; Endothelium, Vascular/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Nitric Oxide Synthase Type III/chemistry ; Nitric Oxide Synthase Type III/genetics ; Phosphorylation ; Reactive Oxygen Species ; Receptors, Adiponectin/genetics ; Receptors, Leptin/genetics ; Serine/genetics ; Serine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice.
Autorzy:
Lavier J; Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Institute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.
Beaumann M; Neonatal Research Laboratory, Clinic of Neonatology, Department Woman-Mother-Child, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Menétrey S; Neonatal Research Laboratory, Clinic of Neonatology, Department Woman-Mother-Child, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Bouzourène K; Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Rosenblatt-Velin N; Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Pialoux V; Inter-University Laboratory of Human Movement Biology EA7424, University of Lyon, Villeurbanne, France.
Mazzolai L; Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Peyter AC; Neonatal Research Laboratory, Clinic of Neonatology, Department Woman-Mother-Child, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Pellegrin M; Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Millet GP; Institute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2021 Oct; Vol. 233 (2), pp. e13700. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji:
Journal Article
MeSH Terms:
Nitric Oxide*/metabolism
Nitric Oxide Synthase Type III*/metabolism
Animals ; Biological Availability ; Endothelium, Vascular/metabolism ; Hypoxia/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Hippocampal AMPA- and NMDA-induced cGMP signals are mainly generated by NO-GC2 and are under tight control by PDEs 1 and 2.
Autorzy:
Giesen J; Institute of Pharmacology and Toxicology, Ruhr-University Bochum, Bochum, Germany.
Mergia E; Institute of Pharmacology and Toxicology, Ruhr-University Bochum, Bochum, Germany.
Koesling D; Institute of Pharmacology and Toxicology, Ruhr-University Bochum, Bochum, Germany.
Russwurm M; Institute of Pharmacology and Toxicology, Ruhr-University Bochum, Bochum, Germany.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 Jan; Vol. 55 (1), pp. 18-31. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
N-Methylaspartate*/pharmacology
Nitric Oxide*/metabolism
Animals ; Cyclic GMP/metabolism ; Hippocampus/metabolism ; Mice ; Phosphoric Diester Hydrolases/metabolism ; Protein Isoforms/metabolism ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inducible nitric oxide synthase inhibitor 1400W increases Na -ATPase levels and activity and ameliorates mitochondrial dysfunction in Ctns null kidney proximal tubular epithelial cells.
Autorzy:
Sumayao R Jr; Chemistry Department, De La Salle University, Manila, Philippines.
Newsholme P; School of Biomedical Sciences, Curtin Health Innovation Research Institute (CHIRI), Curtin University, Perth, Western Australia, Australia.
McMorrow T; Conway Institute, School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2018 Nov; Vol. 45 (11), pp. 1149-1160. Date of Electronic Publication: 2018 Jul 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Knockout Techniques*
Amidines/*pharmacology
Benzylamines/*pharmacology
Epithelial Cells/*drug effects
Kidney Tubules, Proximal/*cytology
Mitochondria/*drug effects
Nitric Oxide Synthase Type II/*antagonists & inhibitors
Sodium-Potassium-Exchanging ATPase/*metabolism
Amino Acid Transport Systems, Neutral/deficiency ; Amino Acid Transport Systems, Neutral/genetics ; Animals ; Apoptosis/drug effects ; Cell Line ; Cell Survival/drug effects ; Enzyme Inhibitors/pharmacology ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Gene Expression Regulation, Enzymologic/drug effects ; Mice ; Mitochondria/pathology ; Nitric Oxide/metabolism ; Nutrients/metabolism ; Oxidative Stress/drug effects
Czasopismo naukowe
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