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Wyszukujesz frazę ""Njoya EM"" wg kryterium: Autor


Wyświetlanie 1-8 z 8
Tytuł :
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Autorzy :
Ebokaiwe AP; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China; Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal University Ndufu Alike-, Ikwo, Nigeria.
Njoya EM; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China; Department of Biochemistry, Faculty of Science, University of Yaoundé I, P.O Box 812, Yaoundé, Cameroon.
Sheng Y; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Zhang Z; College of Chemical Engineering, Sichuan University, Chengdu 610064, China.
Li S; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Zhou Z; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Qiang Z; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Peng T; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Hussein AA; Chemistry Department, Cape Peninsula University of Technology, Bellville Campus, Bellville 7537, Western Cape, South Africa.
Zhang G; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Lu X; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Li L; Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China. Electronic address: .
Wang F; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Oct 01; Vol. 404, pp. 115203. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*immunology
Gene Expression Regulation, Neoplastic/*drug effects
Indoleamine-Pyrrole 2,3,-Dioxygenase/*metabolism
Pyrans/*pharmacology
T-Lymphocytes/*drug effects
Animals ; Anti-Bacterial Agents/pharmacology ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Humans ; Immunosuppression ; Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics ; Mice ; Mice, Inbred C57BL ; Models, Molecular ; Neoplasms, Experimental ; Protein Conformation
Czasopismo naukowe
Tytuł :
Natural Polyketides Isolated from the Endophytic Fungus Phomopsis sp. CAM212 with a Semisynthetic Derivative Downregulating the ERK/IκBα Signaling Pathways.
Autorzy :
Jouda JB; Department of Chemical Engineering, School of Chemical Engineering and Mineral Industries, University of Ngaoundere, Ngaoundere, Cameroon.
Njoya EM; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.; Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Fobofou SAT; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA.
Zhou ZY; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Qiang Z; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Mbazoa CD; Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Brandt W; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany.
Zhang GL; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Wandji J; Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Wang F; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
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Źródło :
Planta medica [Planta Med] 2020 Sep; Vol. 86 (13-14), pp. 1032-1042. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Polyketides/*pharmacology
Animals ; Cyclooxygenase 2 ; Lipopolysaccharides ; MAP Kinase Signaling System ; Mice ; NF-KappaB Inhibitor alpha ; NF-kappa B ; Nitric Oxide ; Nitric Oxide Synthase Type II ; Signal Transduction
Czasopismo naukowe
Tytuł :
Anti-inflammatory and antioxidant properties of leaf extracts of eleven South African medicinal plants used traditionally to treat inflammation.
Autorzy :
Ondua M; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.
Njoya EM; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.
Abdalla MA; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.
McGaw LJ; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2019 Apr 24; Vol. 234, pp. 27-35. Date of Electronic Publication: 2018 Dec 18.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Free Radical Scavengers/*pharmacology
Plant Extracts/*pharmacology
Animals ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/isolation & purification ; Antioxidants/administration & dosage ; Antioxidants/isolation & purification ; Cell Survival/drug effects ; Free Radical Scavengers/administration & dosage ; Free Radical Scavengers/isolation & purification ; Inflammation/drug therapy ; Inflammation/pathology ; Inhibitory Concentration 50 ; Macrophages/drug effects ; Medicine, African Traditional/methods ; Mice ; Plant Extracts/administration & dosage ; Plant Leaves ; Plants, Medicinal ; Quercetin/pharmacology ; RAW 264.7 Cells ; South Africa
Czasopismo naukowe
Tytuł :
4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors.
Autorzy :
Yang L; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
Chen Y; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
He J; Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 610091, China.
Njoya EM; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Chen J; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
Liu S; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
Xie C; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
Huang W; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
Wang F; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Wang Z; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China. Electronic address: .
Li Y; Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 610091, China. Electronic address: .
Qian S; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Mar 15; Vol. 27 (6), pp. 1087-1098. Date of Electronic Publication: 2019 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme Inhibitors/*chemistry
Enzyme Inhibitors/*pharmacology
Indazoles/*chemistry
Indazoles/*pharmacology
Indoleamine-Pyrrole 2,3,-Dioxygenase/*antagonists & inhibitors
Tryptophan Oxygenase/*antagonists & inhibitors
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Humans ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Mice, Inbred BALB C ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/pathology ; Structure-Activity Relationship ; Tryptophan Oxygenase/metabolism
Czasopismo naukowe
Tytuł :
Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.
Autorzy :
Qiang Z; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhou ZY; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Peng T; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Jiang PZ; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Shi N; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Njoya EM; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Azimova B; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.
Liu WL; Ministry of Education Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, China.
Chen WH; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.; College of Life Sciences, Henan Normal University, Xinxiang, China.
Zhang GL; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China. .
Wang F; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China. .
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Źródło :
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2018 Nov 27; Vol. 37 (1), pp. 288. Date of Electronic Publication: 2018 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*therapeutic use
Cyclic Nucleotide Phosphodiesterases, Type 4/*metabolism
Interferon-alpha/*pharmacology
MAP Kinase Kinase Kinases/*antagonists & inhibitors
Proto-Oncogene Proteins/*antagonists & inhibitors
Urinary Bladder Neoplasms/*drug therapy
Aminopyridines/pharmacology ; Animals ; Antiviral Agents/pharmacology ; Benzamides/pharmacology ; Cyclic AMP/metabolism ; Cyclooxygenase 2/biosynthesis ; Cyclopropanes/pharmacology ; Disease Models, Animal ; Drug Synergism ; Enzyme Activation/drug effects ; Female ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; NF-kappa B/metabolism ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/metabolism ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł :
The use of liver slices from the Cape vulture (Gyps coprotheres) to better understand the role of liver toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) in vultures.
Autorzy :
Adawaren EO; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa. Electronic address: .
Mukandiwa L; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa; Biomedical Research Centre, Faculty of Veterinary Science, University of Pretoria, South Africa.
Njoya EM; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa.
Bekker L; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa.
Duncan N; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa.
Naidoo V; Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, South Africa; Biomedical Research Centre, Faculty of Veterinary Science, University of Pretoria, South Africa.
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Źródło :
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2018 Sep; Vol. 62, pp. 147-155. Date of Electronic Publication: 2018 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Falconiformes*/metabolism
Anti-Inflammatory Agents, Non-Steroidal/*toxicity
Liver/*drug effects
Animals ; Avian Proteins/metabolism ; Biological Assay ; Carbazoles/toxicity ; Diclofenac/toxicity ; In Vitro Techniques ; Ketoprofen/toxicity ; Liver/metabolism ; Male ; Meloxicam ; Thiazines/toxicity ; Thiazoles/toxicity
Czasopismo naukowe
Tytuł :
Isolation and characterization of two acaricidal compounds from Calpurnia aurea subsp. aurea (Fabaceae) leaf extract.
Autorzy :
Adenubi OT; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa. .; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Federal University of Agriculture, PMB 2240, Alabata, Abeokuta, Ogun State, Nigeria. .
Ali Abdalla M; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
Ahmed AS; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
Njoya EM; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
McGaw LJ; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
Eloff JN; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
Naidoo V; Biomedical Research Centre, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa.
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Źródło :
Experimental & applied acarology [Exp Appl Acarol] 2018 Jul; Vol. 75 (3), pp. 345-354. Date of Electronic Publication: 2018 May 30.
Typ publikacji :
Journal Article
MeSH Terms :
Acaricides/*isolation & purification
Fabaceae/*chemistry
Plant Extracts/*chemistry
Rhipicephalus/*drug effects
Acaricides/chemistry ; Acaricides/pharmacology ; Animals ; Female ; Glycosides/chemistry ; Glycosides/isolation & purification ; Magnetic Resonance Spectroscopy ; Male ; Mass Spectrometry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
Czasopismo naukowe
Tytuł :
South African medicinal plant extracts active against influenza A virus.
Autorzy :
Mehrbod P; Department of Veterinary Tropical Diseases, University of Pretoria, Pretoria, South Africa.; Influenza and Other Respiratory Viruses Department, Pasteur Institute of IRAN, Tehran, Iran.
Abdalla MA; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.
Njoya EM; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.
Ahmed AS; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.; Federal Institute of Industrial Research, Oshodi, Lagos, Nigeria.
Fotouhi F; Influenza and Other Respiratory Viruses Department, Pasteur Institute of IRAN, Tehran, Iran.
Farahmand B; Influenza and Other Respiratory Viruses Department, Pasteur Institute of IRAN, Tehran, Iran.
Gado DA; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.
Tabatabaian M; Influenza and Other Respiratory Viruses Department, Pasteur Institute of IRAN, Tehran, Iran.
Fasanmi OG; Department of Production Animal Studies, University of Pretoria, Pretoria, South Africa.; Department of Animal Health, Federal College of Animal Health and Production Technology, Ibadan, Nigeria.
Eloff JN; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.
McGaw LJ; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.
Fasina FO; Department of Veterinary Tropical Diseases, University of Pretoria, Pretoria, South Africa. .; ECTAD, Food and Agriculture Organization of the United Nations (FAO), Block P, Level 3, United Nations Complex, UN Avenue, Gigiri, Nairobi, Kenya. .
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Źródło :
BMC complementary and alternative medicine [BMC Complement Altern Med] 2018 Mar 27; Vol. 18 (1), pp. 112. Date of Electronic Publication: 2018 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Influenza A virus/*drug effects
Plant Extracts/*pharmacology
Plants, Medicinal/*chemistry
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/toxicity ; Cell Survival/drug effects ; Dogs ; Hemagglutination Inhibition Tests ; Madin Darby Canine Kidney Cells ; Plant Extracts/chemistry ; Plant Extracts/toxicity ; Primulaceae/chemistry ; Rosales/chemistry ; South Africa
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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