Autor: "Njoya EM" - OpacWWW

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Tytuł:: Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.
Autorzy:: Qiang Z; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhou ZY; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Peng T; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Jiang PZ; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Shi N; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; University of Chinese Academy of Sciences, Beijing, China.
Njoya EM; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.; Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Azimova B; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China.
Liu WL; Ministry of Education Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, China.
Chen WH; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.; College of Life Sciences, Henan Normal University, Xinxiang, China.
Zhang GL; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China. .
Wang F; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2018 Nov 27; Vol. 37 (1), pp. 288. Date of Electronic Publication: 2018 Nov 27.
Typ publikacji:: Journal Article
MeSH Terms:: Antiviral Agents/*therapeutic use
Cyclic Nucleotide Phosphodiesterases, Type 4/*metabolism
Interferon-alpha/*pharmacology
MAP Kinase Kinase Kinases/*antagonists & inhibitors
Proto-Oncogene Proteins/*antagonists & inhibitors
Urinary Bladder Neoplasms/*drug therapy
Aminopyridines/pharmacology ; Animals ; Antiviral Agents/pharmacology ; Benzamides/pharmacology ; Cyclic AMP/metabolism ; Cyclooxygenase 2/biosynthesis ; Cyclopropanes/pharmacology ; Disease Models, Animal ; Drug Synergism ; Enzyme Activation/drug effects ; Female ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; NF-kappa B/metabolism ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/metabolism ; Urinary Bladder Neoplasms/pathology

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