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Wyszukujesz frazę ""No-Observed-Adverse-Effect Level"" wg kryterium: Temat


Tytuł :
[Study of No Observed Adverse Effect Level of Nickel and Its Preliminary Evaluation Biocompatibility].
Autorzy :
He X; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Tang J; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Wen X; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Guan B; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Wang R; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Wang H; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Li H; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Shi J; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Zeng Y; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
Mao Y; Beijing Institute of Medical Device Testing, Beijing, 101111.; Beijing Key Laboratory of Medical Device Testing and Safety Evaluation, Beijing, 101111.
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Źródło :
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation [Zhongguo Yi Liao Qi Xie Za Zhi] 2020 Oct 08; Vol. 44 (5), pp. 448-452.
Typ publikacji :
Journal Article
MeSH Terms :
Equipment and Supplies*/adverse effects
Nickel*/toxicity
No-Observed-Adverse-Effect Level*
Animals ; Rats ; Rats, Sprague-Dawley ; Risk Assessment
Czasopismo naukowe
Tytuł :
A toxicological evaluation of monomethylsilanetriol (MMST) stabilized in acacia gum, a novel silicon preparation.
Autorzy :
Preece KE; AIBMR Life Sciences, Inc, 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Glávits R; Toxi-Coop Zrt, Magyar Jakobinusok tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Murbach T; AIBMR Life Sciences, Inc, 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Endres JR; AIBMR Life Sciences, Inc, 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Hirka G; Toxi-Coop Zrt, Magyar Jakobinusok tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Vértesi A; Toxi-Coop Zrt, Magyar Jakobinusok tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Béres E; Toxi-Coop Zrt, Magyar Jakobinusok tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Szakonyiné IP; Toxi-Coop Zrt, Magyar Jakobinusok tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104782. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
No-Observed-Adverse-Effect Level*
Gum Arabic/*toxicity
Mutagenicity Tests/*methods
Silicon/*toxicity
Administration, Oral ; Animals ; Cell Line ; Cricetinae ; Cricetulus ; Dose-Response Relationship, Drug ; Female ; Gum Arabic/administration & dosage ; Male ; Mice ; Rats ; Rats, Wistar ; Silicon/administration & dosage
Czasopismo naukowe
Tytuł :
Eurycoma longifolia -Infused Coffee-An Oral Toxicity Study.
Autorzy :
Ahmad N; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
Teh BP; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
Halim SZ; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
Zolkifli NA; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
Ramli N; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
Muhammad H; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Shah Alam 40170, Malaysia.
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Źródło :
Nutrients [Nutrients] 2020 Oct 13; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
No-Observed-Adverse-Effect Level*
Coffea/*toxicity
Eurycoma/*chemistry
Food Additives/*toxicity
Plant Extracts/*toxicity
Animals ; Body Weight/drug effects ; Coffea/chemistry ; Drinking/drug effects ; Eating/drug effects ; Eurycoma/adverse effects ; Female ; Food Additives/administration & dosage ; Food Additives/isolation & purification ; Lipid Metabolism/drug effects ; Liver/metabolism ; Male ; Organ Size/drug effects ; Plant Extracts/administration & dosage ; Plant Extracts/isolation & purification ; Platelet Count ; Rats, Sprague-Dawley ; Sex Characteristics
Czasopismo naukowe
Tytuł :
D-10-camphorsulfonic acid: Safety evaluation.
Autorzy :
Fehr M; DSM Nutritional Products, Wurmisweg 576, 4303 Kaiseraugst, Switzerland. Electronic address: .
Appl Á; Charles River, Veszprém, Szabadságpuszta, 8200, Hungary. Electronic address: .
Esdaile DJ; Charles River, Veszprém, Szabadságpuszta, 8200, Hungary. Electronic address: .
Naumann S; ICCR-Roßdorf GmbH, In den Leppsteinswiesen 19, 64380 Roßdorf, Germany. Electronic address: .
Schulz M; ICCR-Roßdorf GmbH, In den Leppsteinswiesen 19, 64380 Roßdorf, Germany. Electronic address: .
Dahms I; DSM Nutritional Products, Wurmisweg 576, 4303 Kaiseraugst, Switzerland. Electronic address: .
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Źródło :
Mutation research [Mutat Res] 2020 Oct - Dec; Vol. 858-860, pp. 503257. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
No-Observed-Adverse-Effect Level*
Camphor/*analogs & derivatives
Chromosome Aberrations/*chemically induced
Mutagenicity Tests/*methods
Animals ; Camphor/toxicity ; Female ; Humans ; Male ; Micronucleus Tests/methods ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Formaldehyde: Another hormesis-inducing chemical.
Autorzy :
Agathokleous E; Key Laboratory of Agrometeorology of Jiangsu Province, Department of Ecology, School of Applied Meteorology, Nanjing University of Information Science & Technology (NUIST), Nanjing, 210044, PR China. Electronic address: .
Calabrese EJ; Department of Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA, 01003, USA.
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Źródło :
Environmental research [Environ Res] 2021 Aug; Vol. 199, pp. 111395. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Hormesis*
Volatile Organic Compounds*
Animals ; Dose-Response Relationship, Drug ; Formaldehyde/toxicity ; Humans ; No-Observed-Adverse-Effect Level ; Plants
Czasopismo naukowe
Tytuł :
Intake of Non-Nutritive Sweeteners in Chilean Children after Enforcement of a New Food Labeling Law that Regulates Added Sugar Content in Processed Foods.
Autorzy :
Martínez X; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Zapata Y; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Pinto V; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Cornejo C; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Elbers M; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.; Hanzehogeschool Groningen, University of Applied Sciences, 9747 AS Groningen, The Netherlands.
Graaf MV; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.; Hanzehogeschool Groningen, University of Applied Sciences, 9747 AS Groningen, The Netherlands.
Villarroel L; Department of Public Health, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Hodgson MI; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Rigotti A; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
Echeverría G; Center for Molecular Nutrition and Chronic Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Región Metropolitana, Chile.
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Źródło :
Nutrients [Nutrients] 2020 May 29; Vol. 12 (6). Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Artificially Sweetened Beverages*
Dietary Sugars*
Fast Foods*
No-Observed-Adverse-Effect Level*
Child Nutritional Physiological Phenomena/*physiology
Eating/*physiology
Food Additives/*administration & dosage
Food Labeling/*legislation & jurisprudence
Non-Nutritive Sweeteners/*administration & dosage
Child ; Chile ; Female ; Food Analysis ; Humans ; Male ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł :
Perfluoroalkyl contaminants in eggs from backyard chickens reared in Italy.
Autorzy :
Gazzotti T; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, 40064 Ozzano Emilia, Italy; Health Sciences and Technologies-Interdepartmental Centre for Industrial Research (CIRI-SDV), University of Bologna, 40064 Ozzano Emilia, Italy. Electronic address: .
Sirri F; Department of Agricultural and Food Sciences (DISTAL), University of Bologna, 40064 Ozzano Emilia, Italy.
Ghelli E; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, 40064 Ozzano Emilia, Italy.
Zironi E; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, 40064 Ozzano Emilia, Italy.
Zampiga M; Department of Agricultural and Food Sciences (DISTAL), University of Bologna, 40064 Ozzano Emilia, Italy.
Pagliuca G; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, 40064 Ozzano Emilia, Italy; Health Sciences and Technologies-Interdepartmental Centre for Industrial Research (CIRI-SDV), University of Bologna, 40064 Ozzano Emilia, Italy.
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Źródło :
Food chemistry [Food Chem] 2021 Nov 15; Vol. 362, pp. 130178. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Exposure/*analysis
Eggs/*analysis
Fluorocarbons/*analysis
Food Contamination/*analysis
Adult ; Aged ; Aged, 80 and over ; Alkanesulfonic Acids/analysis ; Animals ; Bioaccumulation ; Chickens ; Child ; Child, Preschool ; Humans ; Infant ; Italy ; Middle Aged ; No-Observed-Adverse-Effect Level
Czasopismo naukowe
Tytuł :
A mixture of 15 phthalates and pesticides below individual chemical no observed adverse effect levels (NOAELs) produces reproductive tract malformations in the male rat.
Autorzy :
Conley JM; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Lambright CS; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Evans N; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Cardon M; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Medlock-Kakaley E; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Wilson VS; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
Gray LE Jr; U.S. Environmental Protection Agency/Office of Research & Development/Center for Public Health and Environmental Assessment/Public Health and Integrated Toxicology Division, Research Triangle Park, NC 27711, United States. Electronic address: .
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Źródło :
Environment international [Environ Int] 2021 Nov; Vol. 156, pp. 106615. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Pesticides*/toxicity
Animals ; Female ; Genitalia, Male ; Male ; No-Observed-Adverse-Effect Level ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Reproduction ; Testis
Czasopismo naukowe
Tytuł :
Residual nitrite in processed meat products in Costa Rica: Method validation, long-term survey and intake estimations.
Autorzy :
Ledezma-Zamora K; Laboratory of Chemical Analysis, School of Chemistry, Universidad Nacional, Heredia 86-3000, Costa Rica. Electronic address: .
Sánchez-Gutiérrez R; School of Chemistry, Universidad Nacional, Heredia 86-3000, Costa Rica. Electronic address: .
Ramírez-Leiva A; Laboratory of Chemical Analysis, School of Chemistry, Universidad Nacional, Heredia 86-3000, Costa Rica.
Mena-Rivera L; School of Chemistry, Universidad Nacional, Heredia 86-3000, Costa Rica. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Nov 01; Vol. 361, pp. 130082. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Meat Products/*analysis
Nitrites/*analysis
Costa Rica ; Diet ; No-Observed-Adverse-Effect Level ; Research Design ; Time Factors
Czasopismo naukowe
Tytuł :
Disruption of postnatal neurogenesis and adult-stage suppression of synaptic plasticity in the hippocampal dentate gyrus after developmental exposure to sterigmatocystin in rats.
Autorzy :
Takashima K; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Nakajima K; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Shimizu S; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Ojiro R; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Tang Q; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Okano H; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Takahashi Y; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Ozawa S; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Jin M; Laboratory of Veterinary Pathology, College of Veterinary Medicine, Southwest University, No. 2 Tiansheng Road, BeiBei District, Chongqing, 400715, PR China. Electronic address: .
Yoshinari T; Division of Microbiology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan. Electronic address: .
Yoshida T; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
Sugita-Konishi Y; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo, 156-8502, Japan. Electronic address: .
Shibutani M; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Oct 01; Vol. 349, pp. 69-83. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*drug effects
Dentate Gyrus/*drug effects
Neural Stem Cells/*drug effects
Neurogenesis/*drug effects
Neuronal Plasticity/*drug effects
Sterigmatocystin/*toxicity
Animals ; Apoptosis/drug effects ; DNA Breaks, Double-Stranded ; Dentate Gyrus/metabolism ; Dentate Gyrus/pathology ; Dose-Response Relationship, Drug ; Gene Expression Regulation ; Neural Stem Cells/metabolism ; Neural Stem Cells/pathology ; No-Observed-Adverse-Effect Level ; Oxidative Stress/drug effects ; Rats, Sprague-Dawley ; Receptors, Neurotransmitter/genetics ; Receptors, Neurotransmitter/metabolism ; Weaning
Czasopismo naukowe
Tytuł :
Theoretical modeling of structure-toxicity relationship of cyanides.
Autorzy :
Molski M; Quantum Chemistry Department, Faculty of Chemistry, Adam Mickiewicz University of Poznań, ul. Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Oct 01; Vol. 349, pp. 30-39. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Models, Molecular*
Toxicity Tests*
Cyanides/*toxicity
Animals ; Cyanides/chemistry ; Dose-Response Relationship, Drug ; Humans ; Lethal Dose 50 ; Molecular Structure ; No-Observed-Adverse-Effect Level ; Risk Assessment ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Preexisting diabetes mellitus had no effect on the no-observed-adverse-effect-level of acetaminophen in rats.
Autorzy :
Kishi S; Department of Gastroenterology, IMS Sapporo Digestive Disease Center General Hospital.; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Yamakawa K; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Nakano-Narusawa Y; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Kanie S; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Hashimoto N; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Saoo K; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Yokohira M; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Imaida K; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
Matsuda Y; Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University.
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Źródło :
The Journal of toxicological sciences [J Toxicol Sci] 2020; Vol. 45 (3), pp. 151-162.
Typ publikacji :
Journal Article
MeSH Terms :
No-Observed-Adverse-Effect Level*
Acetaminophen/*toxicity
Diabetes Mellitus, Type 2/*physiopathology
Animals ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Hypertrophy ; Male ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Dose-response evaluation of urinary cadmium and kidney injury biomarkers in Chinese residents and dietary limit standards.
Autorzy :
Qing Y; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Yang J; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Zhu Y; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Li Y; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Zheng W; Department of Environmental Health, School of Public Health, Fudan University, Shanghai, 200032, China.
Wu M; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
He G; School of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China. .
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Źródło :
Environmental health : a global access science source [Environ Health] 2021 Jun 30; Vol. 20 (1), pp. 75. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dietary Exposure*/analysis
Dietary Exposure*/standards
Models, Biological*
Cadmium/*urine
Environmental Pollutants/*urine
Kidney Diseases/*urine
Adult ; Albuminuria/epidemiology ; Asian Continental Ancestry Group ; Biological Monitoring ; Biomarkers/urine ; Cadmium/toxicity ; China/epidemiology ; Dose-Response Relationship, Drug ; Environmental Pollutants/toxicity ; Female ; Glucosidases/urine ; Humans ; Kidney Diseases/epidemiology ; Male ; No-Observed-Adverse-Effect Level ; Retinol-Binding Proteins/urine ; beta 2-Microglobulin/urine
Czasopismo naukowe
Tytuł :
Assessment of toxicological potential of sodium carboxymethyl beta-glucan, a novel beta-glucan.
Autorzy :
Preece KE; AIBMR Life Sciences, Inc., 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Glávits R; Toxi-Coop Zrt., Magyar Jakobinusok Tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Murbach TS; AIBMR Life Sciences, Inc., 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Endres JR; AIBMR Life Sciences, Inc., 1425 Broadway, Suite 458, Seattle, WA, 98122, USA. Electronic address: .
Hirka G; Toxi-Coop Zrt., Magyar Jakobinusok Tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Vértesi A; Toxi-Coop Zrt., Magyar Jakobinusok Tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
Szakonyiné IP; Toxi-Coop Zrt., Magyar Jakobinusok Tere 4/B, H-1122, Budapest, Hungary. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jun; Vol. 152, pp. 112226. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article
MeSH Terms :
beta-Glucans/*toxicity
Administration, Oral ; Animals ; Escherichia coli/drug effects ; Female ; Male ; Mutagenicity Tests ; No-Observed-Adverse-Effect Level ; Rats, Wistar ; Saccharomyces cerevisiae/chemistry ; Salmonella typhimurium/drug effects ; Toxicity Tests, Subacute ; beta-Glucans/administration & dosage
Czasopismo naukowe
Tytuł :
13-Weeks subchronic toxicity of isoquercitrin-γ-cyclodextrin (IQC-γCD) molecular inclusion complex in Sprague-Dawley rats.
Autorzy :
Kapoor MP; Taiyo Kagaku Co. Ltd., Nutrition Division, 1-3 Takaramachi, Yokkaichi, Mie, 510-0844, Japan. Electronic address: .
Moriwaki M; Taiyo Kagaku Co. Ltd., Nutrition Division, 1-3 Takaramachi, Yokkaichi, Mie, 510-0844, Japan.
Timm D; Taiyo International Inc., 5960 Golden Hills Dr., Minneapolis, MN, 55416, USA.
Yamagata H; Gotemba Laboratory, BoZo Research Center Inc., 1284, Kamado, Gotemba-shi, Shizuoka, 412-0039, Japan.
Maruyama G; Gotemba Laboratory, BoZo Research Center Inc., 1284, Kamado, Gotemba-shi, Shizuoka, 412-0039, Japan.
Nisihara Y; Gotemba Laboratory, BoZo Research Center Inc., 1284, Kamado, Gotemba-shi, Shizuoka, 412-0039, Japan.
Nakazawa T; Gotemba Laboratory, BoZo Research Center Inc., 1284, Kamado, Gotemba-shi, Shizuoka, 412-0039, Japan.
Takata S; Gotemba Laboratory, BoZo Research Center Inc., 1284, Kamado, Gotemba-shi, Shizuoka, 412-0039, Japan.
Nakamura D; Tsukuba Institute, BoZo Research Center Inc., 8 Okubo, Tsukuba-shi, Ibaraki, 300-2611, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jun; Vol. 152, pp. 112217. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Quercetin/*analogs & derivatives
gamma-Cyclodextrins/*toxicity
Alkaline Phosphatase/blood ; Animals ; Body Weight/drug effects ; Female ; Male ; No-Observed-Adverse-Effect Level ; Organ Size/drug effects ; Quercetin/toxicity ; Rats, Sprague-Dawley ; Sex Factors ; Toxicity Tests, Subchronic
Czasopismo naukowe
Tytuł :
Genotoxicity and subchronic general toxicity assessments of Lactobacillus curvatus WiKim 38 using Sprague-Dawley rats.
Autorzy :
Han JS; Toxicologic Pathology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Back SM; Genetic Toxicology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Cho JW; Toxicologic Pathology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Park HJ; Toxicologic Pathology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Kim WJ; Toxicologic Pathology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Park SH; Genetic Toxicology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Noh JH; Organ Toxicology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Kim YB; Department of Advanced Toxicology Research, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Lee BS; Toxicologic Pathology Research Group, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jun; Vol. 152, pp. 112199. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Lactobacillus/*pathogenicity
Probiotics/*toxicity
Animals ; Bone Marrow Cells/metabolism ; Chromosomes/metabolism ; Escherichia coli/genetics ; Female ; Male ; Micronucleus Tests ; No-Observed-Adverse-Effect Level ; Rats, Sprague-Dawley ; Salmonella typhimurium/genetics ; Toxicity Tests, Acute ; Toxicity Tests, Subchronic
SCR Organism :
Lactobacillus curvatus
Czasopismo naukowe
Tytuł :
Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mice and zebrafish.
Autorzy :
Forner-Piquer I; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Klement W; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Gangarossa G; Université de Paris, BFA, UMR 8251, CNRS, F-75014, Paris, France.
Zub E; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
de Bock F; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Blaquiere M; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Maurice T; MMDN, University of Montpellier, EPHE, INSERM, UMR_S1198, Montpellier, France.
Audinat E; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Faucherre A; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Lasserre F; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31300, Toulouse, France.
Ellero-Simatos S; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31300, Toulouse, France.
Gamet-Payrastre L; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31300, Toulouse, France.
Jopling C; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Marchi N; Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Jun 01; Vol. 278, pp. 116755. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorpyrifos*
Pesticides*/toxicity
Animals ; Female ; Larva ; Male ; Mice ; No-Observed-Adverse-Effect Level ; Zebrafish
Czasopismo naukowe
Tytuł :
Environmentally relevant developmental methylmercury exposures alter neuronal differentiation in a human-induced pluripotent stem cell model.
Autorzy :
Prince LM; School of Health Sciences, Purdue University, West Lafayette, IN, USA; ICF International Inc., Durham, NC, USA.
Neely MD; Dept of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Warren EB; Dept of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Thomas MG; School of Health Sciences, Purdue University, West Lafayette, IN, USA.
Henley MR; School of Health Sciences, Purdue University, West Lafayette, IN, USA.
Smith KK; School of Health Sciences, Purdue University, West Lafayette, IN, USA.
Aschner M; Dept of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Bowman AB; School of Health Sciences, Purdue University, West Lafayette, IN, USA. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jun; Vol. 152, pp. 112178. Date of Electronic Publication: 2021 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation/*drug effects
Induced Pluripotent Stem Cells/*drug effects
Methylmercury Compounds/*toxicity
Neurons/*drug effects
Cell Proliferation/drug effects ; Cell Survival/drug effects ; Forkhead Transcription Factors/metabolism ; Glutathione/metabolism ; Humans ; Microtubule-Associated Proteins/metabolism ; Nerve Tissue Proteins/metabolism ; Neuropeptides/metabolism ; No-Observed-Adverse-Effect Level
Czasopismo naukowe
Tytuł :
Chemical Mixture Calculator - A novel tool for mixture risk assessment.
Autorzy :
Boberg J; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark. Electronic address: .
Bredsdorff L; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Petersen A; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Löbl N; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Jensen BH; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Vinggaard AM; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Nielsen E; Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jun; Vol. 152, pp. 112167. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Software*
Complex Mixtures/*toxicity
Databases, Chemical ; Humans ; Internet ; No-Observed-Adverse-Effect Level ; Phthalic Acids/toxicity ; Risk Assessment
Czasopismo naukowe
Tytuł :
Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): a systematic map.
Autorzy :
Fitch SE; ToxStrategies, 23501 Cinco Ranch Blvd, Suite B226, Katy, TX, 77494, USA.
Payne LE; ToxStrategies, 31 College Place, Suite B118, Asheville, NC, 28801, USA.
van de Ligt JLG; ToxStrategies, 23501 Cinco Ranch Blvd, Suite B226, Katy, TX, 77494, USA.; College of Veterinary Medicine, University of Minnesota, 1365 Gortner Ave, St Paul, MN, 55108, USA.
Doepker C; ToxStrategies, 187 Pavilion Pkwy #223, Newport, KY, 41071, USA.
Handu D; Evidence Analysis Center, Academy of Nutrition and Dietetics, 120 S. Riverside Plaza, Suite 2190, Chicago, IL, 60606, USA.
Cohen SM; Department of Pathology and Microbiology, University of Nebraska Medical Center, 985900 Nebraska Medical Center, Omaha, NE, USA.
Anyangwe N; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5001 Campus Drive, College Park, MD, 20740, USA.
Wikoff D; ToxStrategies, 31 College Place, Suite B118, Asheville, NC, 28801, USA. .
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Źródło :
BMC public health [BMC Public Health] 2021 May 20; Vol. 21 (1), pp. 956. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benchmarking*
Sweetening Agents*
Energy Intake ; Humans ; No-Observed-Adverse-Effect Level ; Nutritional Status
Czasopismo naukowe

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