Autor: "Nogueira TC" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A robust human norovirus replication model in zebrafish larvae.
Autorzy:: Van Dycke J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Ny A; KU Leuven-Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Biodiscovery, Leuven, Belgium.
Conceição-Neto N; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Leuven, Belgium.
Maes J; KU Leuven-Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Biodiscovery, Leuven, Belgium.
Hosmillo M; University of Cambridge-Department of Pathology, Division of Virology, Addenbrooke's Hospital, Cambridge, United Kingdom.
Cuvry A; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Goodfellow I; University of Cambridge-Department of Pathology, Division of Virology, Addenbrooke's Hospital, Cambridge, United Kingdom.
Nogueira TC; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Verbeken E; KU Leuven-Department of Imaging & Pathology, Translational Cell & Tissue Research, Leuven, Belgium.
Matthijnssens J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Leuven, Belgium.
de Witte P; KU Leuven-Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Biodiscovery, Leuven, Belgium.
Neyts J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.; Global Virus Network (GVN), Centers of Excellence.
Rocha-Pereira J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2019 Sep 19; Vol. 15 (9), pp. e1008009. Date of Electronic Publication: 2019 Sep 19 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Norovirus/*pathogenicity
Norovirus/*physiology
Virus Replication/*physiology
Zebrafish/*virology
Animals ; Antiviral Agents/administration & dosage ; Caliciviridae Infections/virology ; Foodborne Diseases/virology ; Gastroenteritis/virology ; Host Microbial Interactions ; Humans ; Larva/virology ; Metagenomics ; Models, Animal ; Norovirus/genetics ; Virus Cultivation/methods ; Virus Replication/drug effects

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Skocz do pozycji: 2.

Tytuł:: Weak C-H···O and C-H···π hydrogen bonds and π-π stacking interactions in a series of four N'-[(E)-(aryl)methylidene]-N-methyl-2-oxo-1,3-oxazolidine-4-carbohydrazides.
Autorzy:: Nogueira TC; Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-FarManguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil.
Pinheiro AC; Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-FarManguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil.
Wardell JL; Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-FarManguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil.
de Souza MV; Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-FarManguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil.
Abberley JP; Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, Scotland.
Harrison WT; Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, Scotland.; Pokaż więcej
Źródło:: Acta crystallographica. Section C, Structural chemistry [Acta Crystallogr C Struct Chem] 2015 Aug; Vol. 71 (Pt 8), pp. 647-52. Date of Electronic Publication: 2015 Jul 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Benzylidene Compounds/*chemistry
Hydrazines/*chemistry
Oxazoles/*chemistry
Crystallography, X-Ray ; Hydrogen Bonding ; Molecular Structure

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Skocz do pozycji: 3.

Tytuł:: GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.
Autorzy:: Nogueira TC; Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium.
Paula FM
Villate O
Colli ML
Moura RF
Cunha DA
Marselli L
Marchetti P
Cnop M
Julier C
Eizirik DL; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2013 May; Vol. 9 (5), pp. e1003532. Date of Electronic Publication: 2013 May 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*genetics
Apoptosis Regulatory Proteins/*genetics
Diabetes Mellitus, Type 1/*genetics
Diabetes Mellitus, Type 2/*genetics
Membrane Proteins/*genetics
Proto-Oncogene Proteins/*genetics
Transcription Factors/*genetics
Aged ; Alternative Splicing/genetics ; Animals ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; DNA-Binding Proteins ; Diabetes Mellitus, Type 1/etiology ; Diabetes Mellitus, Type 2/etiology ; Female ; Gene Knockdown Techniques ; Humans ; Insulin/genetics ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/pathology ; Male ; Membrane Proteins/metabolism ; Mice ; Middle Aged ; Protein Isoforms/genetics ; Proto-Oncogene Proteins/metabolism ; Rats ; Repressor Proteins ; Trans-Activators

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Skocz do pozycji: 4.

Tytuł:: C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells.
Autorzy:: Allagnat F; Laboratoire de Médecine Expérimentale, Université Libre de Bruxelles, Brussels, Belgium.
Fukaya M
Nogueira TC
Delaroche D
Welsh N
Marselli L
Marchetti P
Haefliger JA
Eizirik DL
Cardozo AK; Pokaż więcej
Źródło:: Cell death and differentiation [Cell Death Differ] 2012 Nov; Vol. 19 (11), pp. 1836-46. Date of Electronic Publication: 2012 Jun 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Cytokines/*pharmacology
Insulin-Secreting Cells/*metabolism
Transcription Factor CHOP/*metabolism
Animals ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Line ; Cell Nucleus/metabolism ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 1/pathology ; Endoplasmic Reticulum Stress ; I-kappa B Kinase/metabolism ; Insulin-Secreting Cells/cytology ; Interferon-gamma/pharmacology ; Interleukin-1beta/pharmacology ; Mitochondria/metabolism ; Myeloid Cell Leukemia Sequence 1 Protein ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Transcription Factor CHOP/antagonists & inhibitors ; Transcription Factor CHOP/genetics ; Transcription Factor RelA/metabolism ; Tumor Necrosis Factor-alpha/pharmacology

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Skocz do pozycji: 5.

Tytuł:: The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
Autorzy:: Moore F; Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium. />Santin I
Nogueira TC
Gurzov EN
Marselli L
Marchetti P
Eizirik DL; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31062. Date of Electronic Publication: 2012 Feb 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Apoptosis*
CCAAT-Enhancer-Binding Protein-delta/*physiology
Insulin-Secreting Cells/*pathology
Animals ; Cell Line ; Cytokines/biosynthesis ; Humans ; Inflammation ; Insulin-Secreting Cells/drug effects ; Insulinoma ; Interferon Regulatory Factor-1 ; Rats ; STAT1 Transcription Factor