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Tytuł :
Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases.
Autorzy :
Vinogradova Y; Division of Primary Care, University Park, University of Nottingham, Nottingham NG2 7RD, UK .
Coupland C; Division of Primary Care, University Park, University of Nottingham, Nottingham NG2 7RD, UK.
Hippisley-Cox J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
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Źródło :
BMJ (Clinical research ed.) [BMJ] 2020 Oct 28; Vol. 371, pp. m3873. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*epidemiology
Hormone Replacement Therapy/*statistics & numerical data
Aged ; Case-Control Studies ; Databases, Factual ; Estrogens/administration & dosage ; Estrogens/adverse effects ; Female ; Hormone Replacement Therapy/adverse effects ; Humans ; Incidence ; Middle Aged ; Norpregnenes/administration & dosage ; Norpregnenes/adverse effects ; Progestins/administration & dosage ; Progestins/adverse effects ; Risk Assessment
Czasopismo naukowe
Tytuł :
Tibolon - the only one member of STEARs group.
Autorzy :
Fait T
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Transliterated Title :
Tibolon - jediný zástupce skupiny STEAR.
Źródło :
Casopis lekaru ceskych [Cas Lek Cesk] 2019 Summer; Vol. 158 (3-4), pp. 107-111.
Typ publikacji :
Journal Article
MeSH Terms :
Estrogen Receptor Modulators*/adverse effects
Estrogen Receptor Modulators*/therapeutic use
Norpregnenes*/adverse effects
Norpregnenes*/therapeutic use
Osteoporosis*/prevention & control
Breast Neoplasms/chemically induced ; Climate ; Estrogens ; Female ; Humans ; Menopause ; Progestins
Czasopismo naukowe
Tytuł :
Tibolone Effects on Human Glioblastoma Cell Lines.
Autorzy :
González-Arenas A; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México, México.
De la Fuente-Granada M; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México, México.
Camacho-Arroyo I; Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México, México.
Zamora-Sánchez CJ; Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México, México.
Piña-Medina AG; Facultad de Química, Departamento de Biología, Universidad Nacional Autónoma de México, Ciudad de México, México.
Segura-Uribe J; Unidad de Investigación Médica en Enfermedades Neurológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Guerra-Araiza C; Unidad de Investigación Médica en Farmacología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: .
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Źródło :
Archives of medical research [Arch Med Res] 2019 May; Vol. 50 (4), pp. 187-196. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Hormonal/*therapeutic use
Estrogen Receptor alpha/*metabolism
Glioblastoma/*drug therapy
Norpregnenes/*therapeutic use
Receptors, Progesterone/*metabolism
Antineoplastic Agents, Hormonal/pharmacology ; Cell Line, Tumor ; Female ; Glioblastoma/pathology ; Humans ; Norpregnenes/pharmacology
Czasopismo naukowe
Tytuł :
The effectiveness of quick starting oral contraception containing nomegestrol acetate and 17-β estradiol on ovulation inhibition: A randomized controlled trial.
Autorzy :
Jirakittidul P; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. .
Angsuwathana S; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Rattanachaiyanont M; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Thiampong T; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Neungton C; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Chotrungrote B; Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
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Źródło :
Scientific reports [Sci Rep] 2020 May 29; Vol. 10 (1), pp. 8782. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Comparative Study; Equivalence Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Contraceptives, Oral, Combined/*administration & dosage
Estradiol/*administration & dosage
Megestrol/*administration & dosage
Norpregnadienes/*administration & dosage
Ovulation Inhibition/*drug effects
Adult ; Contraceptives, Oral, Combined/pharmacology ; Drug Combinations ; Estradiol/pharmacology ; Ethinyl Estradiol/administration & dosage ; Ethinyl Estradiol/pharmacology ; Female ; Healthy Volunteers ; Humans ; Megestrol/pharmacology ; Menstrual Cycle ; Norpregnadienes/pharmacology ; Norpregnenes/administration & dosage ; Norpregnenes/pharmacology ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Tibolone, alendronate, and simvastatin enhance implant osseointegration in a preclinical in vivo model.
Autorzy :
Apostu D; Department of Orthopaedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Lucaciu O; Department of Oral Health, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Mester A; Department of Oral Health, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Oltean-Dan D; Department of Orthopaedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Gheban D; Department of Anatomical Pathology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Rares Ciprian Benea H; Department of Orthopaedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
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Źródło :
Clinical oral implants research [Clin Oral Implants Res] 2020 Jul; Vol. 31 (7), pp. 655-668. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Dental Implants*
Osseointegration*
Alendronate ; Animals ; Bone Density ; Female ; Humans ; Norpregnenes ; Ovariectomy ; Rats ; Simvastatin ; Titanium
Czasopismo naukowe
Tytuł :
The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury.
Autorzy :
Crespo-Castrillo A; Consejo Superior de Investigaciones Científicas (CSIC), Instituto Cajal, Madrid, Spain.
Yanguas-Casás N; Consejo Superior de Investigaciones Científicas (CSIC), Instituto Cajal, Madrid, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Arevalo MA; Consejo Superior de Investigaciones Científicas (CSIC), Instituto Cajal, Madrid, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Azcoitia I; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.; Department of Cell Biology, Faculty of Biology, Universidad Complutense, 28040, Madrid, Spain.
Barreto GE; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá D.C., Colombia. .
Garcia-Segura LM; Consejo Superior de Investigaciones Científicas (CSIC), Instituto Cajal, Madrid, Spain. .; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2018 Nov; Vol. 55 (11), pp. 8651-8667. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries/*drug therapy
Cerebral Cortex/*pathology
Gliosis/*drug therapy
Neurons/*pathology
Norpregnenes/*therapeutic use
Wounds, Stab/*drug therapy
Animals ; Astrocytes/drug effects ; Astrocytes/pathology ; Brain Injuries/complications ; Brain Injuries/pathology ; Calcium-Binding Proteins/metabolism ; Cell Count ; Cell Death/drug effects ; DNA-Binding Proteins ; Female ; Glial Fibrillary Acidic Protein/metabolism ; Gliosis/etiology ; Gliosis/pathology ; Image Processing, Computer-Assisted ; Macrophages/drug effects ; Macrophages/metabolism ; Mice, Inbred C57BL ; Microfilament Proteins/metabolism ; Microglia/drug effects ; Microglia/pathology ; Nerve Tissue Proteins/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Norpregnenes/pharmacology ; Nuclear Proteins/metabolism ; Phenotype ; Wounds, Stab/complications ; Wounds, Stab/pathology
Czasopismo naukowe
Tytuł :
Osteoporosis management in Australian general practice: an analysis of current osteoporosis treatment patterns and gaps in practice.
Autorzy :
Naik-Panvelkar P; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia. .
Norman S; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Elgebaly Z; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Elliott J; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Pollack A; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Thistlethwaite J; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Weston C; NPS MedicineWise, Level 7, 418A, Elizabeth Street, Surry Hills, NSW, 2010, Australia.
Seibel MJ; Department of Endocrinology & Metabolism, Concord Repatriation General Hospital, The University of Sydney and Bone Research Program, ANZAC Research Institute, Concord, NSW, 2139, Australia.
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Źródło :
BMC family practice [BMC Fam Pract] 2020 Feb 12; Vol. 21 (1), pp. 32. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Attitude of Health Personnel*
General Practitioners*
Bone Density Conservation Agents/*therapeutic use
Denosumab/*therapeutic use
Diphosphonates/*therapeutic use
Osteoporosis/*drug therapy
Osteoporotic Fractures/*prevention & control
Practice Patterns, Physicians'/*statistics & numerical data
Aged ; Aged, 80 and over ; Australia ; Deprescriptions ; Drug Substitution ; Female ; General Practice ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Norpregnenes/therapeutic use ; Osteoporosis/diagnosis ; Raloxifene Hydrochloride/therapeutic use ; Retrospective Studies ; Teriparatide/therapeutic use ; Thiophenes/therapeutic use
Czasopismo naukowe
Tytuł :
The synthetic progestin, gestodene, affects functional biomarkers in neonatal rat osteoblasts through an estrogen receptor-related mechanism of action.
Autorzy :
Enríquez J; a Departamento de Biología de la Reproducción Carlos Gual Castro , Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ) , Ciudad de México , México.
García G; b Departamento de Química Orgánica , Universidad Nacional Autónoma de México (UNAM) , Ciudad de México , México.
Herrero B; c Departamento de Nefrología y Metabolismo Mineral , INCMNSZ , Ciudad de México , México.
Larrea F; a Departamento de Biología de la Reproducción Carlos Gual Castro , Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ) , Ciudad de México , México.
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Źródło :
Endocrine research [Endocr Res] 2017 Nov; Vol. 42 (4), pp. 269-280. Date of Electronic Publication: 2017 Mar 22.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Estrogens/*pharmacology
Norpregnenes/*pharmacology
Osteoblasts/*drug effects
Progestins/*pharmacology
Receptors, Estrogen/*metabolism
5-alpha Reductase Inhibitors/pharmacology ; Aldo-Keto Reductases/antagonists & inhibitors ; Aldo-Keto Reductases/metabolism ; Animals ; Animals, Newborn ; Binding, Competitive/drug effects ; Biomarkers/metabolism ; Biotransformation ; Cell Proliferation/drug effects ; Cells, Cultured ; Enzyme Inhibitors/pharmacology ; Estrogen Receptor Modulators/pharmacology ; Estrogens/chemistry ; Estrogens/metabolism ; Female ; Norpregnenes/antagonists & inhibitors ; Norpregnenes/chemistry ; Norpregnenes/metabolism ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Osteogenesis/drug effects ; Progestins/antagonists & inhibitors ; Progestins/chemistry ; Progestins/metabolism ; Radioligand Assay ; Rats, Wistar ; Receptors, Estrogen/antagonists & inhibitors ; Receptors, Estrogen/chemistry ; Skull/cytology ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Chronic simultaneous exposure of common carp (Cyprinus carpio) from embryonic to juvenile stage to drospirenone and gestodene at low ng/L level caused intersex.
Autorzy :
Šauer P; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic. Electronic address: .
Tumová J; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic.
Steinbach C; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic.
Golovko O; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic; Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences (SLU), Box 7050, SE-750 07, Uppsala, Sweden.
Komen H; Wageningen University, Animal Breeding and Genomics Centre, Wageningen, the Netherlands.
Maillot-Maréchal E; Institut National de l'Environnement Industriel et des Risques (INERIS), Unité d'Ecotoxicologie in vitro et in vivo, UMR-I 02 SEBIO, Verneuil-en-Halatte, France.
Máchová J; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic.
Grabic R; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic.
Aït-Aïssa S; Institut National de l'Environnement Industriel et des Risques (INERIS), Unité d'Ecotoxicologie in vitro et in vivo, UMR-I 02 SEBIO, Verneuil-en-Halatte, France.
Kocour Kroupová H; University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Vodňany, Czech Republic. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Jan 30; Vol. 188, pp. 109912. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Androstenes/*toxicity
Carps/*growth & development
Endocrine Disruptors/*toxicity
Norpregnenes/*toxicity
Sex Differentiation/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Dose-Response Relationship, Drug ; Gene Expression Regulation, Developmental/drug effects ; Gonads/drug effects ; Hepatopancreas/drug effects ; Hypothalamus/drug effects ; Pituitary Gland/drug effects ; Sex Differentiation/genetics
Czasopismo naukowe
Tytuł :
The synthetic steroid tibolone exerts sex-specific regulation of astrocyte phagocytosis under basal conditions and after an inflammatory challenge.
Autorzy :
Crespo-Castrillo A; Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
Garcia-Segura LM; Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludables (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Arevalo MA; Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain. .; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludables (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. .
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Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2020 Jan 28; Vol. 17 (1), pp. 37. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Inflammation/*pathology
Norpregnenes/*pharmacology
Phagocytosis/*drug effects
Selective Estrogen Receptor Modulators/*pharmacology
Androgen Receptor Antagonists/pharmacology ; Animals ; Estradiol/biosynthesis ; Estrogen Antagonists/pharmacology ; Female ; Glial Fibrillary Acidic Protein/metabolism ; Inflammation/chemically induced ; Lipopolysaccharides ; Male ; Microglia/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
An open-label, two-period comparative study on pharmacokinetics and safety of a combined ethinylestradiol/gestodene transdermal contraceptive patch.
Autorzy :
Zhang C; Department of Pharmacy.
Li H; Institute of Clinical Trial, Peking University Third Hospital, Beijing, People's Republic of China.
Xiong X; Department of Pharmacy.
Zhai S; Department of Pharmacy.
Wei Y; Institute of Clinical Trial, Peking University Third Hospital, Beijing, People's Republic of China.
Zhang S; Institute of Clinical Trial, Peking University Third Hospital, Beijing, People's Republic of China.
Zhang Y; Department of Pharmacy.
Xu L; Institute of Clinical Trial, Peking University Third Hospital, Beijing, People's Republic of China.
Liu L; Department of Pharmacy.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2017 Mar 10; Vol. 11, pp. 725-731. Date of Electronic Publication: 2017 Mar 10 (Print Publication: 2017).
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article
MeSH Terms :
Transdermal Patch*
Contraceptive Agents, Female/*administration & dosage
Contraceptive Agents, Female/*adverse effects
Ethinyl Estradiol/*adverse effects
Ethinyl Estradiol/*pharmacokinetics
Norpregnenes/*adverse effects
Norpregnenes/*pharmacokinetics
Administration, Oral ; Adolescent ; Adult ; Contraceptive Agents, Female/blood ; Contraceptive Agents, Female/pharmacokinetics ; Drug Compounding ; Ethinyl Estradiol/administration & dosage ; Ethinyl Estradiol/blood ; Female ; Healthy Volunteers ; Humans ; Norpregnenes/administration & dosage ; Norpregnenes/blood ; Tablets ; Young Adult
Czasopismo naukowe
Tytuł :
Effects of Tibolone on the Central Nervous System: Clinical and Experimental Approaches.
Autorzy :
Pinto-Almazán R; Unidad de Investigación del Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla km 34.5, Pueblo Zoquiapan, Municipio de Ixtapaluca, MEX, Mexico; Institute for the Developing Mind, Children's Hospital Los Angeles, Los Angeles, CA, USA; Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Segura-Uribe JJ; Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340 Mexico City, Mexico.
Farfán-García ED; Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340 Mexico City, Mexico.
Guerra-Araiza C; Unidad de Investigación Médica en Farmacología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauhtémoc 330, Col. Doctores, Mexico City, Mexico.
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Źródło :
BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 8630764. Date of Electronic Publication: 2017 Jan 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Central Nervous System/*drug effects
Norpregnenes/*pharmacology
Climacteric/drug effects ; Cognition Disorders/drug therapy ; Humans ; Neuronal Plasticity/drug effects ; Norpregnenes/chemistry ; Norpregnenes/therapeutic use ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
Preparation and in vitro/in vivo evaluation of gestodene (GEST) intravaginal ring.
Autorzy :
Li C; Research Center of Biomaterial and Novel Drug Delivery Systems, National Research Institute for Family Planning, Da Hui Si Haidian District, Beijing, PR China / Graduate School of Peking Union Medical College; No. 9, Dongdan No. 3 Avenue, Beijing, PR China.
Ning M; Center of Biomaterial and Novel Drug Delivery Systems, National Research Institute for Family Planning, Da Hui Si Haidian District, Beijing, PR China / Graduate School of Peking Union Medical College; No. 9, Dongdan No. 3 Avenue, Beijing, PR China.
Yao X; Center of Biomaterial and Novel Drug Delivery Systems, National Research Institute for Family Planning, Da Hui Si Haidian District, Beijing, PR China / Graduate School of Peking Union Medical College; No. 9, Dongdan No. 3 Avenue, Beijing, PR China.
Wang Y; Shenyang Pharmaceutical University, Shenyang, China.
Liu Y; Research Center of Biomaterial and Novel Drug Delivery Systems, National Research Institute for Family Planning, Da Hui Si Haidian District, Beijing, PR China.
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Źródło :
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2016 Sep; Vol. 29 (5), pp. 1545-1553.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Carriers*
Intrauterine Devices, Medicated*
Contraceptives, Oral, Synthetic/*administration & dosage
Drug Delivery Systems/*instrumentation
Norpregnenes/*administration & dosage
Administration, Intravaginal ; Animals ; Chromatography, High Pressure Liquid ; Contraceptives, Oral, Synthetic/blood ; Contraceptives, Oral, Synthetic/chemistry ; Contraceptives, Oral, Synthetic/pharmacokinetics ; Delayed-Action Preparations ; Drug Compounding ; Equipment Design ; Female ; In Vitro Techniques ; Models, Biological ; Norpregnenes/blood ; Norpregnenes/chemistry ; Norpregnenes/pharmacokinetics ; Rabbits ; Silicone Elastomers ; Solubility ; Tandem Mass Spectrometry ; Vagina/drug effects
Czasopismo naukowe
Tytuł :
Hormonal Replacement Therapy in Menopausal Women with History of Endometriosis: A Review of Literature.
Autorzy :
Zanello M; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Borghese G; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy. .
Manzara F; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Degli Esposti E; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Moro E; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Raimondo D; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Abdullahi LO; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Arena A; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Terzano P; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Meriggiola MC; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
Seracchioli R; Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy.
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2019 Aug 14; Vol. 55 (8). Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hormone Replacement Therapy*
Endometriosis/*epidemiology
Menopause/*physiology
Estrogen Receptor Modulators/administration & dosage ; Female ; Humans ; Norpregnenes/administration & dosage ; Retrospective Studies
Czasopismo naukowe
Tytuł :
TERT inhibition leads to reduction of IL-6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model.
Autorzy :
González-Giraldo Y; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá DC, Colombia.
Garzón-Benitez AV; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá DC, Colombia.
Forero DA; Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia.
Barreto GE; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá DC, Colombia.
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Źródło :
Journal of neuroendocrinology [J Neuroendocrinol] 2019 Aug; Vol. 31 (8), pp. e12768. Date of Electronic Publication: 2019 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminobenzoates/*pharmacology
Astrocytes/*drug effects
Interleukin-6/*genetics
Naphthalenes/*pharmacology
Neuroprotective Agents/*pharmacology
Norpregnenes/*pharmacology
Palmitic Acid/*pharmacology
Telomerase/*antagonists & inhibitors
Astrocytes/cytology ; Astrocytes/metabolism ; Cells, Cultured ; Drug Interactions ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation/drug effects ; Humans ; Interleukin-6/metabolism ; Interleukin-6/pharmacology ; Telomerase/metabolism ; Telomere Homeostasis/drug effects
Czasopismo naukowe
Tytuł :
Short-term and long-term effects of tibolone in postmenopausal women.
Autorzy :
Formoso G; Emilia-Romagna Health and Welfare Directorate, Community Care Department, Pharmaceuticals and Medical Devices Area, Viale Aldo Moro 21, Bologna, Italy, 40127.
Perrone E
Maltoni S
Balduzzi S
Wilkinson J
Basevi V
Marata AM
Magrini N
D'Amico R
Bassi C
Maestri E
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Źródło :
The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2016 Oct 12; Vol. 10. Cochrane AN: CD008536. Date of Electronic Publication: 2016 Oct 12.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; Systematic Review
MeSH Terms :
Estrogen Receptor Modulators/*therapeutic use
Estrogen Replacement Therapy/*methods
Hot Flashes/*drug therapy
Norpregnenes/*therapeutic use
Postmenopause/*drug effects
Aged ; Breast Neoplasms/chemically induced ; Breast Neoplasms/prevention & control ; Dyspareunia/drug therapy ; Estrogen Receptor Modulators/adverse effects ; Estrogen Replacement Therapy/adverse effects ; Female ; Humans ; Middle Aged ; Neoplasm Recurrence, Local/chemically induced ; Norpregnenes/adverse effects ; Randomized Controlled Trials as Topic ; Stroke/chemically induced ; Sweating/drug effects ; Uterine Hemorrhage/chemically induced
Czasopismo naukowe
Tytuł :
Comparison of combined low-dose hormone therapy vs. tibolone in the prevention of bone loss.
Autorzy :
Kalder M; a Department of Obstetrics and Gynecology , Philipps University of Marburg , Germany ;
Kyvernitakis I; a Department of Obstetrics and Gynecology , Philipps University of Marburg , Germany ;
Hars O; b Statistical Institute , Berlin , Germany ;
Kauka A; a Department of Obstetrics and Gynecology , Philipps University of Marburg , Germany ;
Hadji P; c Department of Bone Oncology, Endocrinology and Reproductive Medicine , Nordwest Hospital , Frankfurt , Germany.
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Źródło :
Climacteric : the journal of the International Menopause Society [Climacteric] 2016 Oct; Vol. 19 (5), pp. 471-7. Date of Electronic Publication: 2016 Jun 27.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Estradiol/*administration & dosage
Norethindrone/*administration & dosage
Norpregnenes/*administration & dosage
Osteoporosis, Postmenopausal/*prevention & control
Absorptiometry, Photon ; Bone Density/drug effects ; Estradiol/adverse effects ; Estrogen Replacement Therapy ; Female ; Humans ; Middle Aged ; Norethindrone/adverse effects ; Norpregnenes/adverse effects ; Prospective Studies ; Uterine Hemorrhage/etiology
Czasopismo naukowe
Tytuł :
Short-term tibolone does not interfere with endothelial function: a double-blinded, randomized, controlled trial.
Autorzy :
Celani MF; a Department of Obstetrics and Gynecology of the Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
Hurtado R; a Department of Obstetrics and Gynecology of the Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
Brandão AH; a Department of Obstetrics and Gynecology of the Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
Maciel da Fonseca AM; a Department of Obstetrics and Gynecology of the Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
Geber S; a Department of Obstetrics and Gynecology of the Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.
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Źródło :
Climacteric : the journal of the International Menopause Society [Climacteric] 2016 Jun; Vol. 19 (3), pp. 299-302. Date of Electronic Publication: 2016 Mar 31.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Estrogen Receptor Modulators*
Endothelium, Vascular/*drug effects
Endothelium, Vascular/*physiology
Norpregnenes/*administration & dosage
Brachial Artery/physiology ; Double-Blind Method ; Female ; Hormone Replacement Therapy ; Humans ; Middle Aged ; Norpregnenes/adverse effects ; Placebos ; Postmenopause ; Prospective Studies ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
Effects of low dose of tibolone on steroid receptors and Bcl-2 on the postmenopausal endometrium.
Autorzy :
Reis BF; Department of Gynecology and Obstetrics, Santa Casa of Sao Paulo Medical School, Sao Paulo and Department of Gynecology and Obstetrics, Vale do Sapucaí University, Pouso Alegre, Minas Gerais, Brazil. .
Lima SM; Department of Gynecology and Obstetrics, Santa Casa of Sao Paulo Medical School, Sao Paulo, Brazil.
Silva GM; Department of Gynecology and Obstetrics, Santa Casa of Sao Paulo Medical School, Sao Paulo, Brazil.
Francisco AM; Department of Gynecology and Obstetrics, Vale do Sapucaí University, Pouso Alegre, Minas Gerais, Brazil.
Barbosa LC; Department of Gynecology and Obstetrics, Vale do Sapucaí University, Pouso Alegre, Minas Gerais, Brazil.
Archangelo SC; Department of Gynecology and Obstetrics, Vale do Sapucaí University, Pouso Alegre, Minas Gerais, Brazil.
Grande RM; Department of Pathology, Vale do Sapucaí University, Pouso Alegre, Minas Gerais, Brazil.
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Źródło :
Histology and histopathology [Histol Histopathol] 2016 Jun; Vol. 31 (6), pp. 629-34. Date of Electronic Publication: 2015 Dec 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Endometrium/*drug effects
Estrogen Receptor Modulators/*therapeutic use
Estrogen Replacement Therapy/*methods
Norpregnenes/*therapeutic use
Double-Blind Method ; Endometrium/metabolism ; Estrogen Receptor Modulators/administration & dosage ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Norpregnenes/administration & dosage ; Postmenopause ; Prospective Studies ; Proto-Oncogene Proteins c-bcl-2/biosynthesis ; Proto-Oncogene Proteins c-bcl-2/drug effects ; Receptors, Estrogen/biosynthesis ; Receptors, Estrogen/drug effects ; Receptors, Progesterone/biosynthesis ; Receptors, Progesterone/drug effects
Czasopismo naukowe
Tytuł :
Antepartum and postpartum uterine artery impedance in women with pre-eclampsia: a case control study.
Autorzy :
Maged AM; a Department of Obstetrics and Gynecology , KasrAlAini Hospital Cairo University , Cairo , Egypt.
Shoab AY; a Department of Obstetrics and Gynecology , KasrAlAini Hospital Cairo University , Cairo , Egypt.
Dieb AS; a Department of Obstetrics and Gynecology , KasrAlAini Hospital Cairo University , Cairo , Egypt.
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Źródło :
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [J Obstet Gynaecol] 2019 Jul; Vol. 39 (5), pp. 633-638. Date of Electronic Publication: 2019 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Postpartum Period*
Pre-Eclampsia/*physiopathology
Uterine Artery/*physiopathology
Adult ; Blood Flow Velocity ; Blood Pressure ; Case-Control Studies ; Cohort Studies ; Egypt ; Electric Impedance ; Female ; Humans ; Norpregnenes ; Pregnancy ; Prenatal Diagnosis ; Pulsatile Flow ; Ultrasonography, Doppler ; Ultrasonography, Prenatal
Czasopismo naukowe

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