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Wyświetlanie 1-6 z 6
Tytuł :
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Autorzy :
Angus DC; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
Derde L; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.; Intensive Care Center, University Medical Center Utrecht, Utrecht, the Netherlands.
Al-Beidh F; Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.
Annane D; Intensive Care Unit, Raymond Poincaré Hospital (AP-HP), Paris, France.; Simone Veil School of Medicine, University of Versailles, Versailles, France.; University Paris Saclay, Garches, France.
Arabi Y; Intensive Care Department, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Beane A; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
van Bentum-Puijk W; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Berry L; Berry Consultants LLC, Austin, Texas.
Bhimani Z; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
Bonten M; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Bradbury C; Bristol Royal Informatory, Bristol, United Kingdom.; University of Bristol, Bristol, United Kingdom.
Brunkhorst F; Center for Clinical Studies and Center for Sepsis Control and Care (CSCC), Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
Buxton M; Global Coalition for Adaptive Research, San Francisco, California.
Buzgau A; Helix, Monash University, Melbourne, Victoria, Australia.
Cheng AC; Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Victoria, Australia.; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
de Jong M; Department of Medical Microbiology, Amsterdam University Medical Center, University of Amsterdam, the Netherlands.
Detry M; Berry Consultants LLC, Austin, Texas.
Estcourt L; NHS Blood and Transplant, Bristol, United Kingdom.; Transfusion Medicine, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
Fitzgerald M; Berry Consultants LLC, Austin, Texas.
Goossens H; Department of Microbiology, Antwerp University Hospital, Antwerp, Belgium.
Green C; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Haniffa R; Network for Improving Critical Care Systems and Training, Colombo, Sri Lanka.; Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Higgins AM; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Horvat C; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
Hullegie SJ; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Kruger P; Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Lamontagne F; Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Lawler PR; Cardiac Intensive Care Unit, Peter Munk Cardiac Centre, University Health Network, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Linstrum K; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Litton E; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.
Lorenzi E; Berry Consultants LLC, Austin, Texas.
Marshall J; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.; Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada.
McAuley D; Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
McGlothin A; Berry Consultants LLC, Austin, Texas.
McGuinness S; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.; Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, Auckland, New Zealand.; The Health Research Council of New Zealand, Wellington, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand.
McVerry B; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Montgomery S; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
Mouncey P; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), London, United Kingdom.
Murthy S; University of British Columbia School of Medicine, Vancouver, Canada.
Nichol A; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.; Department of Anesthesia and Intensive Care, St Vincent's University Hospital, Dublin, Ireland.; School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Department of Intensive Care, Alfred Health, Melbourne, Victoria, Australia.
Parke R; Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, Auckland, New Zealand.; The Health Research Council of New Zealand, Wellington, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand.; School of Nursing, University of Auckland, Auckland, New Zealand.
Parker J; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Rowan K; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), London, United Kingdom.
Sanil A; Berry Consultants LLC, Austin, Texas.
Santos M; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
Saunders C; Berry Consultants LLC, Austin, Texas.
Seymour C; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
Turner A; Medical Research Institute of New Zealand, Wellington, New Zealand.
van de Veerdonk F; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Venkatesh B; Southside Clinical Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia.; The George Institute for Global Health, Sydney, Australia.
Zarychanski R; Department of Medicine, Critical Care and Hematology/Medical Oncology, University of Manitoba, Winnipeg, Manitoba, Canada.
Berry S; Berry Consultants LLC, Austin, Texas.
Lewis RJ; Berry Consultants LLC, Austin, Texas.; Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California.; Department of Emergency Medicine, David Geffen School of Medicine at University of California, Los Angeles.
McArthur C; Medical Research Institute of New Zealand, Wellington, New Zealand.; Department of Critical Care Medicine, Auckland City Hospital, Auckland, New Zealand.
Webb SA; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.; St John of God Hospital, Subiaco, Western Australia, Australia.
Gordon AC; Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.
Al-Beidh F
Angus D
Annane D
Arabi Y
van Bentum-Puijk W
Berry S
Beane A
Bhimani Z
Bonten M
Bradbury C
Brunkhorst F
Buxton M
Cheng A
De Jong M
Derde L
Estcourt L
Goossens H
Gordon A
Green C
Haniffa R
Lamontagne F
Lawler P
Litton E
Marshall J
McArthur
McAuley D
McGuinness S
McVerry B
Montgomery S
Mouncey P
Murthy S
Nichol A
Parke R
Rowan K
Seymour C
Turner A
van de Veerdonk F
Webb S
Zarychanski R
Campbell L
Forbes A
Gattas D
Heritier S
Higgins L
Kruger P
Peake S
Presneill J
Seppelt I
Trapani T
Young P
Bagshaw S
Daneman N
Ferguson N
Misak C
Santos M
Hullegie S
Pletz M
Rohde G
Rowan K
Alexander B
Basile K
Girard T
Horvat C
Huang D
Linstrum K
Vates J
Beasley R
Fowler R
McGloughlin S
Morpeth S
Paterson D
Venkatesh B
Uyeki T
Baillie K
Duffy E
Fowler R
Hills T
Orr K
Patanwala A
Tong S
Netea M
Bihari S
Carrier M
Fergusson D
Goligher E
Haidar G
Hunt B
Kumar A
Laffan M
Lawless P
Lother S
McCallum P
Middeldopr S
McQuilten Z
Neal M
Pasi J
Schutgens R
Stanworth S
Turgeon A
Weissman A
Adhikari N
Anstey M
Brant E
de Man A
Lamonagne F
Masse MH
Udy A
Arnold D
Begin P
Charlewood R
Chasse M
Coyne M
Cooper J
Daly J
Gosbell I
Harvala-Simmonds H
Hills T
MacLennan S
Menon D
McDyer J
Pridee N
Roberts D
Shankar-Hari M
Thomas H
Tinmouth A
Triulzi D
Walsh T
Wood E
Calfee C
O’Kane C
Shyamsundar M
Sinha P
Thompson T
Young I
Bihari S
Hodgson C
Laffey J
McAuley D
Orford N
Neto A
Detry M
Fitzgerald M
Lewis R
McGlothlin A
Sanil A
Saunders C
Berry L
Lorenzi E
Miller E
Singh V
Zammit C
van Bentum Puijk W
Bouwman W
Mangindaan Y
Parker L
Peters S
Rietveld I
Raymakers K
Ganpat R
Brillinger N
Markgraf R
Ainscough K
Brickell K
Anjum A
Lane JB
Richards-Belle A
Saull M
Wiley D
Bion J
Connor J
Gates S
Manax V
van der Poll T
Reynolds J
van Beurden M
Effelaar E
Schotsman J
Boyd C
Harland C
Shearer A
Wren J
Clermont G
Garrard W
Kalchthaler K
King A
Ricketts D
Malakoutis S
Marroquin O
Music E
Quinn K
Cate H
Pearson K
Collins J
Hanson J
Williams P
Jackson S
Asghar A
Dyas S
Sutu M
Murphy S
Williamson D
Mguni N
Potter A
Porter D
Goodwin J
Rook C
Harrison S
Williams H
Campbell H
Lomme K
Williamson J
Sheffield J
van’t Hoff W
McCracken P
Young M
Board J
Mart E
Knott C
Smith J
Boschert C
Affleck J
Ramanan M
D’Souza R
Pateman K
Shakih A
Cheung W
Kol M
Wong H
Shah A
Wagh A
Simpson J
Duke G
Chan P
Cartner B
Hunter S
Laver R
Shrestha T
Regli A
Pellicano A
McCullough J
Tallott M
Kumar N
Panwar R
Brinkerhoff G
Koppen C
Cazzola F
Brain M
Mineall S
Fischer R
Biradar V
Soar N
White H
Estensen K
Morrison L
Smith J
Cooper M
Health M
Shehabi Y
Al-Bassam W
Hulley A
Whitehead C
Lowrey J
Gresha R
Walsham J
Meyer J
Harward M
Venz E
Williams P
Kurenda C
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Garcia R
Barge D
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Driscoll A
Fortune L
Janin P
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Ashelford A
Waterson S
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McNamara R
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Coles J
Schweikert S
Wibrow B
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Dawda A
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Maguire T
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Salerno T
Sterba M
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Duplaix M
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Zapalac M
Mirković G
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Kutleša M
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Vujaklija Brajković A
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Sever H
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Kušan I
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Pokaż więcej
Corporate Authors :
Writing Committee for the REMAP-CAP Investigators
Źródło :
JAMA [JAMA] 2020 Oct 06; Vol. 324 (13), pp. 1317-1329.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Inflammatory Agents/*administration & dosage
Coronavirus Infections/*drug therapy
Hydrocortisone/*administration & dosage
Pneumonia, Viral/*drug therapy
Respiration, Artificial/*statistics & numerical data
Adrenal Cortex Hormones/therapeutic use ; Adult ; Anti-Inflammatory Agents/adverse effects ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/mortality ; Coronavirus Infections/therapy ; Early Termination of Clinical Trials ; Female ; Humans ; Hydrocortisone/adverse effects ; Intensive Care Units ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Shock/drug therapy ; Shock/etiology ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
    Wyświetlanie 1-6 z 6

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