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Wyświetlanie 1-17 z 17
Czasopismo naukowe
Tytuł:
Presenilin E318G variant and Alzheimer's disease risk: the Cache County study.
Autorzy:
Hippen AA; Department of Biology, Brigham Young University, Provo, UT, USA.
Ebbert MT; Department of Biology, Brigham Young University, Provo, UT, USA.
Norton MC; Department of Psychology, Utah State University, Logan, UT, USA.
Tschanz JT; Department of Psychology, Utah State University, Logan, UT, USA.
Munger RG; Department of Nutrition, Dietetics, and Food Science, Utah State University, Logan, UT, USA.
Corcoran CD; Department of Mathematics and Statistics, Utah State University, Logan, UT, USA.
Kauwe JS; Department of Biology, Brigham Young University, Provo, UT, USA. .
Pokaż więcej
Źródło:
BMC genomics [BMC Genomics] 2016 Jun 29; Vol. 17 Suppl 3, pp. 438. Date of Electronic Publication: 2016 Jun 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Mutation, Missense*
Polymorphism, Single Nucleotide*
Alzheimer Disease/*genetics
Genetic Predisposition to Disease/*genetics
Presenilin-1/*genetics
Aged ; Aged, 80 and over ; Alleles ; Apolipoprotein E4/genetics ; Case-Control Studies ; Epistasis, Genetic ; Gene Frequency ; Genotype ; Humans ; Logistic Models ; Odds Ratio ; Risk Factors ; Utah
Czasopismo naukowe
Tytuł:
Dementia caregivers' coping strategies and their relationship to health and well-being: the Cache County Study.
Autorzy:
Snyder CM; a Psychology Department , Utah State University , Logan , UT , USA.
Fauth E
Wanzek J
Piercy KW
Norton MC
Corcoran C
Rabins PV
Lyketsos CG
Tschanz JT
Pokaż więcej
Źródło:
Aging & mental health [Aging Ment Health] 2015; Vol. 19 (5), pp. 390-9. Date of Electronic Publication: 2014 Aug 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Adaptation, Psychological*
Anxiety/*psychology
Caregivers/*psychology
Dementia/*nursing
Aged ; Disease Progression ; Female ; Health Status ; Humans ; Longitudinal Studies ; Male ; Mental Health ; Neuropsychological Tests ; Parent-Child Relations ; Stress, Psychological
Czasopismo naukowe
Tytuł:
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.
Autorzy:
Cruchaga C; Department of Psychiatry, Washington University, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University St. Louis, MO, USA.
Karch CM; Department of Psychiatry, Washington University, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University St. Louis, MO, USA.
Jin SC; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Benitez BA; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Cai Y; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Guerreiro R; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Harari O; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Norton J; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Budde J; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Bertelsen S; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Jeng AT; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Cooper B; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Skorupa T; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Carrell D; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Levitch D; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Hsu S; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Choi J; Department of Psychiatry, Washington University, St. Louis, MO, USA.
Ryten M; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; on behalf of UKBEC (UK Brain Expression Consortium).
Sassi C; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Bras J; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.
Gibbs RJ; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Hernandez DG; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Lupton MK; Institute of Psychiatry, King's College London, London, UK.; Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Powell J; Institute of Psychiatry, King's College London, London, UK.
Forabosco P; Istituto di Genetica delle Popolazioni - CNR, Sassari, Italy.
Ridge PG; Department of Biology, Brigham Young University, Provo, UT, 84602.
Corcoran CD; Department of Mathematics and Statistics, Utah State University, Logan, UT.; Center for Epidemiologic Studies, Utah State University, Logan, UT.
Tschanz JT; Center for Epidemiologic Studies, Utah State University, Logan, UT.; Department of Psychology, Utah State University, Logan, UT.
Norton MC; Center for Epidemiologic Studies, Utah State University, Logan, UT.; Department of Psychology, Utah State University, Logan, UT.; Department of Family Consumer and Human Development, Utah State University, Logan, UT.
Munger RG; Department of Family Consumer and Human Development, Utah State University, Logan, UT.; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT.
Schmutz C; Department of Biology, Brigham Young University, Provo, UT, 84602.
Leary M; Department of Biology, Brigham Young University, Provo, UT, 84602.
Demirci FY; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA.
Bamne MN; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA.
Wang X; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA.
Lopez OL; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA.
Ganguli M; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA.
Medway C; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Turton J; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Lord J; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Braae A; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Barber I; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Brown K; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Pastor P; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.; Department of Neurology, Clínica Universidad de Navarra, School of Medicine, University of Navarra, Pamplona, Spain.; CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Spain.
Lorenzo-Betancor O; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Brkanac Z; University of Washington. Seattle, WA.
Scott E; The Scripps Research Institute, La Jolla, CA, US.
Topol E; The Scripps Research Institute, La Jolla, CA, US.
Morgan K; Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Rogaeva E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto.
Singleton A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Hardy J; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.
Kamboh MI; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA.
George-Hyslop PS; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto.; Cambridge Institute for Medical Research, and the Department of Clinical Neurosciences, University of Cambridge.
Cairns N; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University St. Louis, MO, USA.; Pathology and Immunology, Washington University, St. Louis, MO, USA.
Morris JC; Pathology and Immunology, Washington University, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.; Knight ADRC, Washington University, St. Louis, MO, USA.
Kauwe JSK; Department of Biology, Brigham Young University, Provo, UT, 84602.
Goate AM; Department of Psychiatry, Washington University, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.; Knight ADRC, Washington University, St. Louis, MO, USA.; Department of Genetics, Washington University, St. Louis, MO, USA.
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Corporate Authors:
Alzheimer's Research UK (ARUK) Consortium
Źródło:
Nature [Nature] 2014 Jan 23; Vol. 505 (7484), pp. 550-554. Date of Electronic Publication: 2013 Dec 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*genetics
Genetic Predisposition to Disease/*genetics
Genetic Variation/*genetics
Phospholipase D/*genetics
Black or African American/genetics ; Age of Onset ; Aged ; Aged, 80 and over ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Brain/metabolism ; Case-Control Studies ; Europe/ethnology ; Exome/genetics ; Female ; Humans ; Male ; Peptide Fragments/metabolism ; Phospholipase D/deficiency ; Phospholipase D/metabolism ; Protein Processing, Post-Translational/genetics ; Proteolysis
Czasopismo naukowe
Tytuł:
Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging.
Autorzy:
Ridge PG
Maxwell TJ
Foutz SJ
Bailey MH
Corcoran CD
Tschanz JT
Norton MC
Munger RG
O'Brien E
Kerber RA
Cawthon RM
Kauwe JS
Pokaż więcej
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2014; Vol. 15 Suppl 7, pp. S6. Date of Electronic Publication: 2014 May 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging*
DNA Copy Number Variations*
Genome, Mitochondrial*
DNA, Mitochondrial/*genetics
Aged ; Amino Acid Sequence ; Animals ; Electron Transport Complex IV/chemistry ; Electron Transport Complex IV/genetics ; Female ; Genetic Variation ; Haplotypes ; Humans ; Longevity ; Male ; Mitochondria/genetics ; Molecular Sequence Data ; Sequence Alignment
Czasopismo naukowe
Tytuł:
Population substructure in Cache County, Utah: the Cache County study.
Autorzy:
Sharp AR
Ridge PG
Bailey MH
Boehme KL
Norton MC
Tschanz JT
Munger RG
Corcoran CD
Kauwe JS
Pokaż więcej
Corporate Authors:
Alzheimer's Disease Neuroimaging Initiative
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2014; Vol. 15 Suppl 7, pp. S8. Date of Electronic Publication: 2014 May 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetics, Population*
Alzheimer Disease/*genetics
Ethnicity/genetics ; HapMap Project ; Homozygote ; Humans ; Utah ; White People/genetics
Czasopismo naukowe
Tytuł:
The Cache County Study on Memory in Aging: factors affecting risk of Alzheimer's disease and its progression after onset.
Autorzy:
Tschanz JT; Department of Psychology, Utah State University , Logan, UT.
Norton MC
Zandi PP
Lyketsos CG
Pokaż więcej
Źródło:
International review of psychiatry (Abingdon, England) [Int Rev Psychiatry] 2013 Dec; Vol. 25 (6), pp. 673-85.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Alzheimer Disease/*epidemiology
Cognition Disorders/*epidemiology
Aged ; Aged, 80 and over ; Aging/physiology ; Alzheimer Disease/drug therapy ; Alzheimer Disease/genetics ; Cognition Disorders/drug therapy ; Cognition Disorders/genetics ; Disease Progression ; Female ; Humans ; Incidence ; Male ; Memory/physiology ; Prevalence ; Prospective Studies ; Risk Factors ; Stress, Psychological/complications ; Stress, Psychological/epidemiology ; Utah/epidemiology
Czasopismo naukowe
Tytuł:
Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging.
Autorzy:
Ridge PG; Department of Biology, Brigham Young University, Provo, Utah, USA.
Maxwell TJ
Corcoran CD
Norton MC
Tschanz JT
O'Brien E
Kerber RA
Cawthon RM
Munger RG
Kauwe JS
Pokaż więcej
Źródło:
PloS one [PLoS One] 2012; Vol. 7 (9), pp. e45134. Date of Electronic Publication: 2012 Sep 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Predisposition to Disease*
Memory*
Aging/*genetics
Alzheimer Disease/*genetics
Alzheimer Disease/*physiopathology
Genome, Mitochondrial/*genetics
Haplotypes/*genetics
Aged ; DNA, Mitochondrial/genetics ; Demography ; Female ; Genetic Variation ; Humans ; Male ; Risk Factors ; Utah
Czasopismo naukowe
    Wyświetlanie 1-17 z 17

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