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Tytuł :
Functional control of Eco1 through the MCM complex in sister chromatid cohesion.
Autorzy :
Yoshimura A; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.
Sutani T; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. Electronic address: .
Shirahige K; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jun 05; Vol. 784, pp. 145584. Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Acetyltransferases/*metabolism
Cell Cycle Proteins/*metabolism
Chromatids/*metabolism
Chromosomal Proteins, Non-Histone/*metabolism
Nuclear Proteins/*metabolism
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*metabolism
Acetylation ; Acetyltransferases/chemistry ; Acetyltransferases/genetics ; Binding Sites ; Chromosomes, Fungal/metabolism ; Mutation ; Nuclear Proteins/chemistry ; Nuclear Proteins/genetics ; Protein Binding ; Protein Stability ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Autorzy :
Chen Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Wang Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Chen J; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Zuo W; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Fan Y; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Huang S; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Liu Y; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Chen G; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.; Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, Huzhou University, Huzhou Central Hospital, Zhenjiang, China.
Li Q; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Li J; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Wu J; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Bian Q; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai, China.
Huang C; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Institute of Precision Medicine, Shanghai, China. .
Lei M; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Institute of Precision Medicine, Shanghai, China. .; Key laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Źródło :
Nature communications [Nat Commun] 2021 May 26; Vol. 12 (1), pp. 3176. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Meiotic Prophase I*
Cell Cycle Proteins/*metabolism
Membrane Proteins/*metabolism
Microtubule-Associated Proteins/*metabolism
Nuclear Proteins/*metabolism
Telomere/*metabolism
Animals ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/isolation & purification ; Cell Cycle Proteins/ultrastructure ; Cell Line, Tumor ; Crystallography, X-Ray ; Cyclin-Dependent Kinase 2/genetics ; Cyclin-Dependent Kinase 2/isolation & purification ; Cyclin-Dependent Kinase 2/metabolism ; Cyclin-Dependent Kinase 2/ultrastructure ; Female ; HEK293 Cells ; Humans ; Male ; Membrane Proteins/genetics ; Membrane Proteins/isolation & purification ; Membrane Proteins/ultrastructure ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/isolation & purification ; Microtubule-Associated Proteins/ultrastructure ; Mutation ; Nuclear Proteins/genetics ; Nuclear Proteins/isolation & purification ; Nuclear Proteins/ultrastructure ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Recombinant Proteins/ultrastructure
Czasopismo naukowe
Tytuł :
Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Autorzy :
Lee YT; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Accent Therapeutics, 65 Hayden Avenue, Lexington, MA, USA.
Ayoub A; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Park SH; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Sha L; Department of Medicine, Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA.
Xu J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Mao F; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Zheng W; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Zhang Y; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Cho US; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Dou Y; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. .; Department of Medicine, Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 19; Vol. 12 (1), pp. 2953. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*chemistry
DNA-Binding Proteins/*metabolism
Histone-Lysine N-Methyltransferase/*metabolism
Myeloid-Lymphoid Leukemia Protein/*metabolism
Nuclear Proteins/*chemistry
Nuclear Proteins/*metabolism
Transcription Factors/*chemistry
Transcription Factors/*metabolism
Animals ; Cell Line ; Chromatin/metabolism ; Cryoelectron Microscopy ; DNA-Binding Proteins/genetics ; Histones/metabolism ; Human Embryonic Stem Cells/metabolism ; Humans ; In Vitro Techniques ; Intrinsically Disordered Proteins/chemistry ; Intrinsically Disordered Proteins/metabolism ; Magnetic Resonance Spectroscopy ; Mice ; Models, Molecular ; Mouse Embryonic Stem Cells/metabolism ; Nuclear Proteins/genetics ; Nucleosomes/metabolism ; Nucleosomes/ultrastructure ; Protein Conformation ; Protein Interaction Domains and Motifs ; Scattering, Small Angle ; Transcription Factors/genetics ; X-Ray Diffraction
Czasopismo naukowe
Tytuł :
Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.
Autorzy :
Supper E; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Rudat S; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Iyer V; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Droop A; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Wong K; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Spinella JF; The Leucegene Project at Institute for Research in Immunology and Cancer, Université de Montréal, 2950 Chemin de Polytechnique Pavillon, Marcelle-Coutu, Montréal, QC, Canada.
Thomas P; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Sauvageau G; The Leucegene Project at Institute for Research in Immunology and Cancer, Université de Montréal, 2950 Chemin de Polytechnique Pavillon, Marcelle-Coutu, Montréal, QC, Canada.
Adams DJ; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK.
Wong CC; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, UK. .; Department of Haematology, Addenbrooke's Hospital, Cambridge, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Apr 30; Vol. 12 (1), pp. 2482. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Haploinsufficiency*
Apoptosis/*genetics
CASP8 and FADD-Like Apoptosis Regulating Protein/*metabolism
Gene Expression Regulation, Neoplastic/*genetics
Homeodomain Proteins/*metabolism
Leukemia, Myeloid, Acute/*metabolism
Nuclear Proteins/*metabolism
Repressor Proteins/*metabolism
Animals ; Apoptosis/drug effects ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cell Survival/genetics ; Chromatin Immunoprecipitation ; Dipeptides/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Ontology ; Genes, Tumor Suppressor ; Hematopoietic Stem Cells/metabolism ; Homeodomain Proteins/genetics ; Humans ; Indoles/pharmacology ; Kaplan-Meier Estimate ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/mortality ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Myelomonocytic, Chronic/genetics ; Leukemia, Myelomonocytic, Chronic/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mutation ; Nuclear Proteins/deficiency ; Nuclear Proteins/genetics ; Promoter Regions, Genetic ; Protein Array Analysis ; Repressor Proteins/deficiency ; Repressor Proteins/genetics ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Tytuł :
High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Autorzy :
Höfler S; Leibniz University Hannover, Institute for Organic Chemistry and Centre for Biomolecular Drug Research (BMWZ), D-30167 Hannover, Germany.
Lukat P; Helmholtz Centre for Infection Research, Department of Structure and Function of Proteins, D-38124 Braunschweig, Germany.
Blankenfeldt W; Helmholtz Centre for Infection Research, Department of Structure and Function of Proteins, D-38124 Braunschweig, Germany.
Carlomagno T; Leibniz University Hannover, Institute for Organic Chemistry and Centre for Biomolecular Drug Research (BMWZ), D-30167 Hannover, Germany.; Helmholtz Centre for Infection Research, Group of NMR-based Structural Chemistry, D-38124 Braunschweig, Germany.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Apr; Vol. 27 (4), pp. 496-512. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Archaeal Proteins/*chemistry
Chromosomal Proteins, Non-Histone/*chemistry
Nuclear Proteins/*chemistry
Pyrococcus furiosus/*genetics
Ribonucleoproteins, Small Nucleolar/*chemistry
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*chemistry
Amino Acid Sequence ; Archaeal Proteins/genetics ; Archaeal Proteins/metabolism ; Binding Sites ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; Crystallography, X-Ray ; Gene Expression ; Methylation ; Models, Molecular ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Pyrococcus furiosus/metabolism ; RNA, Fungal/genetics ; RNA, Fungal/metabolism ; RNA, Guide/genetics ; RNA, Guide/metabolism ; RNA, Ribosomal/genetics ; RNA, Ribosomal/metabolism ; RNA, Small Nucleolar/genetics ; RNA, Small Nucleolar/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Ribonucleoproteins, Small Nuclear/chemistry ; Ribonucleoproteins, Small Nuclear/genetics ; Ribonucleoproteins, Small Nuclear/metabolism ; Ribonucleoproteins, Small Nucleolar/genetics ; Ribonucleoproteins, Small Nucleolar/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Sequence Alignment ; Structural Homology, Protein
Czasopismo naukowe
Tytuł :
Minimal residual disease monitoring in acute myeloid leukemia with non-A/B/D-NPM1 mutations by digital polymerase chain reaction: feasibility and clinical use.
Autorzy :
Lesieur A; CHU Lille, Laboratory of Hematology, F-59000 Lille.
Thomas X; Hospices Civils de Lyon, Lyon-Sud University Hospital, Department of Hematology, Lyon.
Nibourel O; CHU Lille, Laboratory of Hematology, F-59000 Lille, FRANCE; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille.
Boissel N; AP-HP, Saint-Louis Hospital, Department of Hematology, Saint-Louis Research Institute, Université de Paris, Paris.
Fenwarth L; CHU Lille, Laboratory of Hematology, F-59000 Lille, FRANCE; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille.
De Botton S; Gustave Roussy Institute, Department of Hematology, Villejuif.
Fournier E; CHU Lille, Laboratory of Hematology, F-59000 Lille, FRANCE; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille.
Celli-Lebras K; AP-HP, Saint-Louis Hospital, Department of Hematology, Saint-Louis Research Institute, Université de Paris, Paris.
Raffoux E; AP-HP, Saint-Louis Hospital, Department of Hematology, Saint-Louis Research Institute, Université de Paris, Paris.
Recher C; Toulouse Cancer University Institute, Department of Hematology, Toulouse.
Lambert J; CH Versailles, Department of Hematology, Le Chesnay.
Berthon C; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, FRANCE; CHU Lille, Department of Clinic Hematology, F-59000 Lille.
Pigneux A; Bordeaux Haut-Lévêque University Hospital, Department of Hematology, Pessac.
Itzykson R; AP-HP, Saint-Louis Hospital, Department of Hematology, Saint-Louis Research Institute, Université de Paris, Paris.
Turlure P; CHU Limoges, Univ. Limoges, Department of Hematology, Limoges.
Pautas C; AP-HP, Department of Hematology, Henri Mondor Hospital, Créteil.
Vargaftig J; Curie Hospital, René Huguenin Hospital, Saint-Cloud.
Preudhomme C; CHU Lille, Laboratory of Hematology, F-59000 Lille, FRANCE; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille.
Dombret H; AP-HP, Saint-Louis Hospital, Department of Hematology, Saint-Louis Research Institute, Université de Paris, Paris.
Duployez N; CHU Lille, Laboratory of Hematology, F-59000 Lille, FRANCE; Univ. Lille, CNRS, Inserm, CHU Lille, Institut de Recherche contre le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille. .
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Źródło :
Haematologica [Haematologica] 2021 Jun 01; Vol. 106 (6), pp. 1767-1769. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Letter
MeSH Terms :
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Nuclear Proteins*/genetics
Feasibility Studies ; Humans ; Mutation ; Neoplasm, Residual
Opinia redakcyjna
Tytuł :
The BAG2 and BAG6 Genes Are Involved in Multiple Abiotic Stress Tolerances in Arabidopsis Thaliana .
Autorzy :
Arif M; Tianjin Key Laboratory of Protein Sciences, Department of Plant Biology and Ecology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Li Z; Tianjin Key Laboratory of Protein Sciences, Department of Plant Biology and Ecology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Luo Q; Tianjin Key Laboratory of Protein Sciences, Department of Plant Biology and Ecology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Li L; Tianjin Key Laboratory of Protein Sciences, Department of Plant Biology and Ecology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Shen Y; State Key Laboratory of Medicinal Chemical Biology, Nankai University, 94 Weijin Road, Tianjin 300071, China.; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Men S; Tianjin Key Laboratory of Protein Sciences, Department of Plant Biology and Ecology, College of Life Sciences, Nankai University, Tianjin 300071, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 29; Vol. 22 (11). Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptation, Physiological*
Stress, Physiological*
Arabidopsis/*genetics
Arabidopsis/*metabolism
Arabidopsis Proteins/*genetics
Mitochondrial Proteins/*genetics
Molecular Chaperones/*genetics
Nuclear Proteins/*genetics
Arabidopsis Proteins/metabolism ; Droughts ; Mitochondrial Proteins/metabolism ; Molecular Chaperones/metabolism ; Mutation ; Nuclear Proteins/metabolism ; Plant Development/genetics ; Plant Growth Regulators/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
High expression of guanine nucleotide-binding protein-like-3-like is associated with poor prognosis in esophageal cancer.
Autorzy :
Dai G; Department of Pathology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou.
Guo Z; Department of Pathology, Huai'an First People's Hospital, Huai'an.
Chen H; Department of Pathology, Taizhou Second People's Hospital, Yangzhou University of Medicine, Taizhou.
Jiang M; Department of Pathology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou.
Zhou H; Department of Pathology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou.
Bao J; Department of Pathology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou.
Yu H; Department of Pathology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou.
Huang J; Department of Oncology, Taizhou People's Hospital, Nanjing University of Traditional Chinese Medicine, Taizhou, Jiangsu, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 May 28; Vol. 100 (21), pp. e25993.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Biomarkers, Tumor/*metabolism
Esophageal Neoplasms/*mortality
Esophageal Squamous Cell Carcinoma/*mortality
GTP-Binding Proteins/*metabolism
Nuclear Proteins/*metabolism
Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers, Tumor/analysis ; Cell Nucleus/pathology ; Cell Proliferation ; Chemotherapy, Adjuvant/methods ; Cytoplasm/pathology ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/therapy ; Esophageal Squamous Cell Carcinoma/genetics ; Esophageal Squamous Cell Carcinoma/pathology ; Esophageal Squamous Cell Carcinoma/therapy ; Esophagectomy ; Esophagus/cytology ; Esophagus/pathology ; Esophagus/surgery ; Female ; GTP-Binding Proteins/analysis ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Nuclear Proteins/analysis ; Prognosis ; Up-Regulation
Czasopismo naukowe
Tytuł :
Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling.
Autorzy :
Yeh FL; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Chang SL; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Ahmed GR; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Liu HI; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Tung L; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Yeh CS; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Lanier LS; Department of Biology, Washington and Lee University, Lexington, VA, USA.
Maeder C; Department of Chemistry, Trinity University, San Antonio, TX, USA.
Lin CM; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Tsai SC; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Hsiao WY; Genomics Research Center, Academia Sinica, Taipei, Taiwan.; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chang WH; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.
Chang TH; Genomics Research Center, Academia Sinica, Taipei, Taiwan. .
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Źródło :
Nature communications [Nat Commun] 2021 May 25; Vol. 12 (1), pp. 3082. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Splicing*
DEAD-box RNA Helicases/*metabolism
Nuclear Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Spliceosomes/*metabolism
Adenosine Triphosphate/metabolism ; DEAD-box RNA Helicases/genetics ; Humans ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Mutation ; Nuclear Proteins/genetics ; Phosphorylation ; Protein Binding ; RNA Helicases/genetics ; RNA Helicases/metabolism ; RNA Precursors/genetics ; RNA Precursors/metabolism ; RNA-Binding Proteins/genetics ; Ribonuclease H/metabolism ; Ribonucleoproteins, Small Nuclear/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Spliceosomes/genetics
Czasopismo naukowe
Tytuł :
Eukaryote specific RNA and protein features facilitate assembly and catalysis of H/ACA snoRNPs.
Autorzy :
Trucks S; Institute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438 Frankfurt, Germany.
Hanspach G; Institute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438 Frankfurt, Germany.
Hengesbach M; Institute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438 Frankfurt, Germany.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 May 07; Vol. 49 (8), pp. 4629-4642.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hydro-Lyases/*metabolism
Microtubule-Associated Proteins/*metabolism
Nuclear Proteins/*metabolism
RNA, Small Nucleolar/*metabolism
RNA-Binding Proteins/*metabolism
Ribonucleoproteins, Small Nuclear/*metabolism
Ribonucleoproteins, Small Nucleolar/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Catalysis ; Escherichia coli/metabolism ; Fluorescence Resonance Energy Transfer ; Gene Expression ; Hydro-Lyases/genetics ; In Vitro Techniques ; Inverted Repeat Sequences ; Microtubule-Associated Proteins/genetics ; Models, Molecular ; Nuclear Proteins/genetics ; Protein Domains ; RNA Folding ; RNA, Guide ; RNA, Small Nucleolar/genetics ; RNA-Binding Proteins/genetics ; Recombinant Proteins ; Ribonucleoproteins, Small Nuclear/genetics ; Ribonucleoproteins, Small Nucleolar/genetics ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication.
Autorzy :
Hossain M; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
Bhalla K; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
Stillman B; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 May 06; Vol. 81 (9), pp. 1951-1969.e6. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Replication*
Mitosis*
ATPases Associated with Diverse Cellular Activities/*metabolism
Cell Cycle Proteins/*metabolism
Cell Nucleus/*metabolism
Intrinsically Disordered Proteins/*metabolism
Nuclear Proteins/*metabolism
Origin Recognition Complex/*metabolism
AAA Domain ; ATPases Associated with Diverse Cellular Activities/genetics ; Cell Cycle Proteins/genetics ; Cell Nucleus/genetics ; Cyclin A/genetics ; Cyclin A/metabolism ; Cyclin E/genetics ; Cyclin E/metabolism ; G1 Phase ; HeLa Cells ; Humans ; Intrinsically Disordered Proteins/genetics ; Nuclear Proteins/genetics ; Origin Recognition Complex/genetics ; Phosphorylation ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Phosphatase 1/genetics ; Protein Phosphatase 1/metabolism ; Protein Stability ; S-Phase Kinase-Associated Proteins/genetics ; S-Phase Kinase-Associated Proteins/metabolism
Czasopismo naukowe
Tytuł :
Genetic biomarkers identify a subgroup of high-risk patients within low-risk NPM1 -mutated acute myeloid leukemia.
Autorzy :
Carbonell D; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
Suárez-González J; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.; Genomics Unit, Gregorio Marañón General University Hospital, IiSGM, Madrid, Spain.
Chicano M; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
Andrés-Zayas C; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.; Genomics Unit, Gregorio Marañón General University Hospital, IiSGM, Madrid, Spain.
Díez-Díez M; Genomics Unit, Gregorio Marañón General University Hospital, IiSGM, Madrid, Spain.
Rodríguez-Macías G; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.
Muñiz P; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
Kwon M; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
Anguita J; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
Díez-Martín JL; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.; Department of Medicine, School of Medicine, Complutense University of Madrid, Madrid, Spain.
Buño I; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.; Genomics Unit, Gregorio Marañón General University Hospital, IiSGM, Madrid, Spain.; Department of Cell Biology, School of Medicine, Complutense University of Madrid, Madrid, Spain.
Martínez-Laperche C; Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2021 May; Vol. 62 (5), pp. 1178-1186. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Nuclear Proteins*/genetics
Humans ; Mutation ; Prognosis ; Recurrence ; Risk ; fms-Like Tyrosine Kinase 3/genetics
Czasopismo naukowe
Tytuł :
The Nuclear Transport Protein Importin-5: A Promising Target in Oncology and Virology.
Autorzy :
Patouret R; Faculty of Science, Department of Organic Chemistry, 30 quai Ernest Ansermet, CH-1211 Geneva 4;, Email: .
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Źródło :
Chimia [Chimia (Aarau)] 2021 Apr 28; Vol. 75 (4), pp. 319-322.
Typ publikacji :
Journal Article
MeSH Terms :
Nuclear Proteins*/metabolism
beta Karyopherins*/metabolism
Active Transport, Cell Nucleus ; Cell Nucleus/metabolism ; Karyopherins/metabolism
Czasopismo naukowe
Tytuł :
Loss of Speckle-Type POZ Protein Promotes Prostate Cancer Cell Migration and Invasion Through Upregulation of MCP-1.
Autorzy :
Shi J; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Cao J; Department of Experimental Pathology, Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China (mainland).
Lu X; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Fan L; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Guo H; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Fu J; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2021 Apr 19; Vol. 27, pp. e929199. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2/*metabolism
Nuclear Proteins/*metabolism
Prostatic Neoplasms/*metabolism
Repressor Proteins/*metabolism
Antibodies, Blocking/metabolism ; Cell Movement ; Cell Proliferation ; Chemokine CCL2/genetics ; Chemokine CCL2/immunology ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Male ; Mutation/genetics ; Neoplasm Invasiveness ; Nuclear Proteins/genetics ; Prostatic Neoplasms/pathology ; Repressor Proteins/genetics ; Tumor Cells, Cultured ; Up-Regulation ; Wound Healing/genetics
Czasopismo naukowe
Tytuł :
The Eyes Absent Proteins: Unusual HAD Family Tyrosine Phosphatases.
Autorzy :
Roychoudhury K; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Hegde RS; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 10; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Evolution, Molecular*
Genome, Human/*genetics
Hydrolases/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Nuclear Proteins/*genetics
Protein Tyrosine Phosphatases/*genetics
Cysteine/metabolism ; Humans ; Hydrolases/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Nuclear Proteins/metabolism ; Protein Tyrosine Phosphatases/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.
Autorzy :
Shen Y; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Halabelian L; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Chau I; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Dela Seña C; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Park KS; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Meng F; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Chen H; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Zeng H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Dong A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Wu H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Trush VV; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
McLeod D; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Zepeda-Velázquez CA; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Campbell RM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States.
Mader MM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States.
Watson BM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States.
Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Al-Awar R; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Kaniskan HÜ; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Jin J; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Apr 08; Vol. 64 (7), pp. 3697-3706. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzodiazepinones/*pharmacology
Enzyme Inhibitors/*pharmacology
Nuclear Proteins/*antagonists & inhibitors
Protein-Arginine N-Methyltransferases/*antagonists & inhibitors
Allosteric Regulation ; Allosteric Site ; Benzodiazepinones/chemical synthesis ; Benzodiazepinones/metabolism ; Crystallography, X-Ray ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/metabolism ; HEK293 Cells ; Humans ; Nuclear Proteins/metabolism ; Protein Binding ; Protein-Arginine N-Methyltransferases/metabolism ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development.
Autorzy :
Espinola SM; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France.
Götz M; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France.
Bellec M; IGMM, CNRS, Univ Montpellier, Montpellier, France.
Messina O; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France.; IGMM, CNRS, Univ Montpellier, Montpellier, France.
Fiche JB; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France.
Houbron C; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France.
Dejean M; IGMM, CNRS, Univ Montpellier, Montpellier, France.
Reim I; Department of Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Cardozo Gizzi AM; Centro de Investigación en Medicina Traslacional Severo Amuchastegui, Instituto Universitario de Ciencias Biomédicas de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas, Córdoba, Argentina.
Lagha M; IGMM, CNRS, Univ Montpellier, Montpellier, France. .
Nollmann M; Centre de Biologie Structurale, CNRS UMR 5048, INSERM U1054, Univ Montpellier, Montpellier, France. .
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Źródło :
Nature genetics [Nat Genet] 2021 Apr; Vol. 53 (4), pp. 477-486. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Cell Lineage/*genetics
Chromatin/*chemistry
Drosophila Proteins/*genetics
Drosophila melanogaster/*genetics
Nuclear Proteins/*genetics
Transcription Factors/*genetics
Animals ; Cell Differentiation ; Chromatin/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster/cytology ; Drosophila melanogaster/growth & development ; Drosophila melanogaster/metabolism ; Embryo, Nonmammalian ; Enhancer Elements, Genetic ; Gene Expression Profiling ; Genomics ; Nuclear Proteins/metabolism ; Promoter Regions, Genetic ; Single-Cell Analysis ; Transcription Factors/classification ; Transcription Factors/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
[Expression and Clinical Significance of CD73 in Acute Myeloid Leukemia Patients with NPM1 Mutation].
Autorzy :
Zhang JZ; Department of Hematology, Jingzhou Central Hospital, Jingzhou 434020, Hubei Province,China.
Liu M; Department of Hematology, Jingzhou Central Hospital, Jingzhou 434020, Hubei Province,China.
Huang ZP; Department of Hematology, Jingzhou Central Hospital, Jingzhou 434020, Hubei Province,China,E-mail:.
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Apr; Vol. 29 (2), pp. 416-421.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid, Acute*/genetics
Nuclear Proteins*/genetics
Humans ; Mutation ; Prognosis ; Survival Rate ; fms-Like Tyrosine Kinase 3
Czasopismo naukowe
Tytuł :
[Methodological Research on Rapid Detection and Genotyping of NPM1 Gene Mutations in Leukemia].
Autorzy :
Chen C; Engineering Research Center of Natural Medicine, Ministry of Eduction, Beijing Normal University,Beijing 100875, China,College of Engineering, Beijing Normal University, Zhuhai 519087, Guangdong Province, China.
Lin J; College of Engineering, Beijing Normal University, Zhuhai 519087, Guangdong Province, China.
Long K; College of Engineering, Beijing Normal University, Zhuhai 519087, Guangdong Province, China.
Yang YC; Faculty of Education, Beijing Normal University, Beijing 100081, China,E-mail: .
Li ZP; College of Engineering, Beijing Normal University, Zhuhai 519087, Guangdong Province, China,E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Apr; Vol. 29 (2), pp. 403-407.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid, Acute*/genetics
Nuclear Proteins*/genetics
Exons ; Genotype ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
DNA-driven condensation assembles the meiotic DNA break machinery.
Autorzy :
Claeys Bouuaert C; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA. .; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium. .
Pu S; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA.
Wang J; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Oger C; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium.
Daccache D; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium.
Xie W; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Patel DJ; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Keeney S; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA. .
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Źródło :
Nature [Nature] 2021 Apr; Vol. 592 (7852), pp. 144-149. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Meiosis*
Saccharomyces cerevisiae*/cytology
Saccharomyces cerevisiae*/genetics
DNA, Fungal/*metabolism
Nuclear Proteins/*metabolism
Nucleoproteins/*metabolism
Recombinases/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
DNA, Fungal/chemistry ; Endodeoxyribonucleases/metabolism ; Homologous Recombination ; Nuclear Proteins/chemistry ; Nucleoproteins/chemistry ; Protein Binding ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Recombinases/chemistry ; Saccharomyces cerevisiae Proteins/chemistry
Czasopismo naukowe

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