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Wyszukujesz frazę ""Nucleoside"" wg kryterium: Temat


Tytuł:
Leishmania donovani secretory protein nucleoside diphosphate kinase b localizes in its nucleus and prevents ATP mediated cytolysis of macrophages.
Autorzy:
Kushawaha PK; Department of Microbiology, Central University of Punjab, Bathinda, India.
Pati Tripathi CD; Division of Parasitology, CSIR- Central Drug Research Institute, Lucknow, India.
Dube A; Division of Parasitology, CSIR- Central Drug Research Institute, Lucknow, India. Electronic address: anuradha_.
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Źródło:
Microbial pathogenesis [Microb Pathog] 2022 May; Vol. 166, pp. 105457. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
Leishmania donovani*
Nucleoside-Diphosphate Kinase*/genetics
Nucleoside-Diphosphate Kinase*/metabolism
Adenosine Triphosphate/metabolism ; Cell Death ; Macrophages/metabolism ; NM23 Nucleoside Diphosphate Kinases/metabolism
Czasopismo naukowe
Tytuł:
Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions.
Autorzy:
Hermann R; Clinical Research Appliance (cr.appliance), Heinrich-Vingerhut-Weg 3, 63571, Gelnhausen, Germany. .
Krajcsi P; Habilitas Kft, Budapest, Hungary.
Fluck M; Merck Healthcare KGaA, Darmstadt, Germany.
Seithel-Keuth A; Merck Healthcare KGaA, Darmstadt, Germany.
Bytyqi A; Merck Healthcare KGaA, Darmstadt, Germany.
Galazka A; An Affiliate of Merck KGaA, Ares Trading SA, Eysins, Switzerland.
Munafo A; An Affiliate of Merck KGaA, Merck Institute of Pharmacometrics, Lausanne, Switzerland.
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Źródło:
Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Feb; Vol. 61 (2), pp. 167-187. Date of Electronic Publication: 2021 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cladribine*/pharmacology
Nucleoside Transport Proteins*
ATP Binding Cassette Transporter, Subfamily G, Member 2 ; ATP-Binding Cassette Transporters ; Drug Interactions ; Equilibrative Nucleoside Transporter 1/metabolism ; Humans ; Membrane Transport Proteins/metabolism ; Neoplasm Proteins/metabolism
Czasopismo naukowe
Tytuł:
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor.
Autorzy:
Lacombe ML; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France.
Lamarche F; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
De Wever O; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.
Padilla-Benavides T; Molecular Biology and Biochemistry Department, Wesleyan University, Middletown, USA.
Carlson A; Molecular Biology and Biochemistry Department, Wesleyan University, Middletown, USA.
Khan I; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, USA.
Huna A; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France.
Vacher S; Unit of Pharmacogenetics, Department of Genetics, Curie Institute, Paris, France.
Calmel C; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France.
Desbourdes C; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Cottet-Rousselle C; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Hininger-Favier I; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Attia S; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Nawrocki-Raby B; Reims Champagne Ardenne University, INSERM, P3Cell UMR-S 1250, SFR CAP-SANTE, Reims, France.
Raingeaud J; INSERM U1279, Gustave Roussy Institute, Villejuif, France.
Machon C; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France.
Guitton J; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France.
Le Gall M; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France.
Clary G; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France.
Broussard C; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France.
Chafey P; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France.
Thérond P; AP-HP, CHU Bicêtre, Laboratory of Biochemistry, Le Kremlin-Bicêtre Hospital, Le Kremlin-Bicêtre, France.; EA7537, Paris Saclay University, Châtenay-Malabry, France.
Bernard D; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France.
Fontaine E; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Tokarska-Schlattner M; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France.
Steeg P; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, USA.
Bièche I; Unit of Pharmacogenetics, Department of Genetics, Curie Institute, Paris, France.
Schlattner U; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), Institut Universitaire de France (IUF), Grenoble, France. .
Boissan M; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France. .; AP-HP, Laboratory of Biochemistry and Hormonology, Tenon Hospital, Paris, France. .
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Źródło:
BMC biology [BMC Biol] 2021 Oct 21; Vol. 19 (1), pp. 228. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/genetics
Neoplasms*/metabolism
Nucleoside-Diphosphate Kinase*/genetics
Nucleoside-Diphosphate Kinase*/metabolism
Animals ; Intracellular Membranes ; Mice ; Mitochondria ; NM23 Nucleoside Diphosphate Kinases/genetics ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Nucleoside Diphosphate Kinase D/metabolism
Czasopismo naukowe
Tytuł:
Concentrative Nucleoside Transporter, CNT, Results in Selective Toxicity of Toyocamycin against Candida albicans.
Autorzy:
Ojima Y; Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, Osaka, Japan.
Yokota N; Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, Osaka, Japan.
Tanibata Y; Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, Osaka, Japan.
Nerome S; Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, Osaka, Japan.
Azuma M; Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, Osaka, Japan.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2022 Aug 31; Vol. 10 (4), pp. e0113822. Date of Electronic Publication: 2022 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Candida albicans*/genetics
Candida albicans*/metabolism
Nucleoside Transport Proteins*/genetics
Nucleoside Transport Proteins*/metabolism
Adenosine/metabolism ; Humans ; Purine Nucleosides/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Toyocamycin/metabolism
Czasopismo naukowe
Tytuł:
Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.
Autorzy:
Khan I; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Building 37, Convent Drive, Room 1126, Bethesda, MD, 20892, USA. .
Gril B; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Building 37, Convent Drive, Room 1126, Bethesda, MD, 20892, USA.
Hoshino A; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA.; Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Yang HH; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, USA.
Lee MP; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, USA.
Difilippantonio S; Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Lyden DC; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA.; Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Steeg PS; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Building 37, Convent Drive, Room 1126, Bethesda, MD, 20892, USA.
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Źródło:
Clinical & experimental metastasis [Clin Exp Metastasis] 2022 Oct; Vol. 39 (5), pp. 815-831. Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*
Exosomes*
Lung Neoplasms*/secondary
NM23 Nucleoside Diphosphate Kinases*/genetics
NM23 Nucleoside Diphosphate Kinases*/metabolism
Cell Line, Tumor ; Female ; Humans ; Liposomes ; Neoplasm Metastasis ; Proteomics
Czasopismo naukowe
Tytuł:
Probing Queuosine Modifications of Transfer RNA in Single Living Cells via Plasmonic Affinity Sandwich Assay.
Autorzy:
Xie D; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Wen Y; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Chen J; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Lu H; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
He H; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Liu Z; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
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Źródło:
Analytical chemistry [Anal Chem] 2022 Sep 20; Vol. 94 (37), pp. 12828-12835. Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Nucleoside Q*/analysis
Nucleoside Q*/genetics
Nucleoside Q*/metabolism
RNA, Transfer*/metabolism
Humans ; Male ; RNA Processing, Post-Transcriptional
Czasopismo naukowe
Tytuł:
Extracellular 5'-methylthioadenosine inhibits intracellular symmetric dimethylarginine protein methylation of FUSE-binding proteins.
Autorzy:
Tang B; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Lee HO; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Gupta S; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Wang L; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Kurimchak AM; Cancer Signaling and Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Duncan JS; Cancer Signaling and Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Kruger WD; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102367. Date of Electronic Publication: 2022 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Arginine N-Methyltransferases*/genetics
Protein-Arginine N-Methyltransferases*/metabolism
Purine-Nucleoside Phosphorylase*/genetics
Purine-Nucleoside Phosphorylase*/metabolism
Arginine/analogs & derivatives ; DNA-Binding Proteins/metabolism ; Deoxyadenosines ; Homozygote ; Humans ; Methionine/metabolism ; Methylation ; Pemetrexed/metabolism ; Polyamines ; RNA-Binding Proteins/metabolism ; Sequence Deletion ; Thionucleosides
Czasopismo naukowe
Tytuł:
Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.
Autorzy:
Abt ER; Department of Molecular and Medical Pharmacology and.
Rashid K; Department of Molecular and Medical Pharmacology and.
Le TM; Department of Molecular and Medical Pharmacology and.
Li S; Department of Molecular and Medical Pharmacology and.
Lee HR; Department of Molecular and Medical Pharmacology and.
Lok V; Department of Molecular and Medical Pharmacology and.
Li L; Department of Surgery, UCLA, Los Angeles, California, USA.
Creech AL; Department of Molecular and Medical Pharmacology and.
Labora AN; Department of Surgery, UCLA, Los Angeles, California, USA.
Mandl HK; Department of Surgery, UCLA, Los Angeles, California, USA.
Lam AK; Department of Molecular and Medical Pharmacology and.
Cho A; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Rezek V; Department of Medicine.
Wu N; Department of Surgery, UCLA, Los Angeles, California, USA.
Abril-Rodriguez G; Department of Molecular and Medical Pharmacology and.
Rosser EW; Department of Molecular and Medical Pharmacology and.
Mittelman SD; Division of Pediatric Endocrinology, UCLA Children's Discovery and Innovation Institute, and.
Hugo W; Division of Dermatology, Department of Medicine, UCLA, Los Angeles, California, USA.
Mehrling T; Laevoroc Oncology, Zug, Switzerland.
Bantia S; Laevoroc Oncology, Zug, Switzerland.
Ribas A; Department of Molecular and Medical Pharmacology and.; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA.; Division of Hematology/Oncology, Department of Medicine.; Division of Surgical Oncology, Department of Surgery.; Jonsson Comprehensive Cancer Center.
Donahue TR; Department of Molecular and Medical Pharmacology and.; Department of Surgery, UCLA, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center.
Crooks GM; Division of Pediatric Hematology-Oncology, Department of Pediatrics.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and.; Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, California, USA.
Wu TT; Department of Molecular and Medical Pharmacology and.
Radu CG; Department of Molecular and Medical Pharmacology and.; Jonsson Comprehensive Cancer Center.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2022 Aug 15; Vol. 132 (16).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunologic Deficiency Syndromes*
Purine-Nucleoside Phosphorylase*/genetics
Purine-Nucleoside Phosphorylase*/metabolism
Animals ; Autoimmunity ; Humans ; Mice ; Purine Nucleosides ; T-Lymphocytes ; Toll-Like Receptor 7
Czasopismo naukowe
Tytuł:
Inborn Errors of Nucleoside Transporter (NT)-Encoding Genes ( SLC28 and SLC29 ).
Autorzy:
Pastor-Anglada M; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain.; Institut de Recerca Sant Joan de Déu (IR SJD), Esplugues de Llobregat, 08950 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBER EHD), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Mata-Ventosa A; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain.; Institut de Recerca Sant Joan de Déu (IR SJD), Esplugues de Llobregat, 08950 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBER EHD), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Pérez-Torras S; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain.; Institut de Recerca Sant Joan de Déu (IR SJD), Esplugues de Llobregat, 08950 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBER EHD), Instituto de Salud Carlos III, 28029 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 07; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Blood Group Antigens*
Nucleoside Transport Proteins*/genetics
Nucleoside Transport Proteins*/metabolism
Humans ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Nucleosides/metabolism ; Nucleotides/metabolism
Czasopismo naukowe
Tytuł:
Queuosine salvage in fission yeast by Qng1-mediated hydrolysis to queuine.
Autorzy:
Patel BI; Institut für Biologie, Lebenswissenschaftliche Fakultät, Humboldt-Universität zu Berlin, 10099, Berlin, Germany.
Heiss M; Ludwig-Maximilians-Universität München, Department of Chemistry and Biochemistry, Butenandtstraße 5-13, 81377, München, Germany.
Samel-Pommerencke A; Institut für Biologie, Lebenswissenschaftliche Fakultät, Humboldt-Universität zu Berlin, 10099, Berlin, Germany.
Carell T; Ludwig-Maximilians-Universität München, Department of Chemistry and Biochemistry, Butenandtstraße 5-13, 81377, München, Germany.
Ehrenhofer-Murray AE; Institut für Biologie, Lebenswissenschaftliche Fakultät, Humboldt-Universität zu Berlin, 10099, Berlin, Germany. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 08; Vol. 624, pp. 146-150. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleoside Q*/metabolism
Schizosaccharomyces*/genetics
Schizosaccharomyces*/metabolism
Animals ; Bacteria/metabolism ; Guanine/analogs & derivatives ; Humans ; Hydrolysis ; Mice ; Nucleosides/metabolism ; RNA, Transfer/genetics ; RNA, Transfer/metabolism
Czasopismo naukowe
Tytuł:
The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12.
Autorzy:
Pollo-Oliveira L; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
Davis NK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Hossain I; Department of Physics, Williams College, Williamstown, MA 01267, USA.
Ho P; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore 138602, Singapore.
Yuan Y; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
Salguero García P; Department of Applied Statistics, Operations Research and Quality, Universitat Politècnica de València, Valencia 46022, Spain.
Pereira C; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
Byrne SR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Leng J; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sze M; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
Blaby-Haas CE; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
Sekowska A; Kodikos Labs, 23 rue Baldassini, Lyon 69007, France.
Montoya A; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Begley T; The RNA Institute and Department of Biology, University at Albany, Albany, NY 12222, USA.
Danchin A; Kodikos Labs, 23 rue Baldassini, Lyon 69007, France.; School of Biomedical Sciences, Li Kashing Faculty of Medicine, University of Hong Kong, Pokfulam, SAR Hong Kong.
Aalberts DP; Department of Physics, Williams College, Williamstown, MA 01267, USA.
Angerhofer A; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Hunt J; Department of Biological Sciences, Columbia University, New York, NY 10024, USA.
Conesa A; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.; Institute for Integrative Systems Biology, Spanish National Research Council, Paterna 46980, Spain.
Dedon PC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore 138602, Singapore.
de Crécy-Lagard V; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.; Genetic Institute, University of Florida, Gainesville, FL 32611, USA.
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Źródło:
Metallomics : integrated biometal science [Metallomics] 2022 Sep 24; Vol. 14 (9).
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli K12*/genetics
Escherichia coli K12*/metabolism
Nucleoside Q*/metabolism
Anticodon ; Cadmium ; Cobalt ; Homeostasis ; Hydrogen Peroxide ; Nickel ; Oxidative Stress ; Paraquat ; Phenotype ; Proteomics ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł:
Analysis of queuosine and 2-thio tRNA modifications by high throughput sequencing.
Autorzy:
Katanski CD; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
Watkins CP; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
Zhang W; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
Reyer M; Program of Biophysics, University of Chicago, Chicago, IL 60637, USA.
Miller S; Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
Pan T; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Sep 23; Vol. 50 (17), pp. e99.
Typ publikacji:
Journal Article
MeSH Terms:
Anticodon*/genetics
Nucleoside Q*/chemistry
Amino Acids/genetics ; Animals ; Escherichia coli/genetics ; Escherichia coli/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Mammals/genetics ; Periodic Acid ; RNA, Transfer/metabolism ; Sulfur
Czasopismo naukowe
Tytuł:
Differential Proteomics of Helicobacter pylori Isolates from Gastritis, Ulcer, and Cancer Patients: First Study from Northwest Pakistan.
Autorzy:
Shah SAR; Department of Microbiology, Abdul Wali Khan University, Mardan 23200, KP, Pakistan.
Rahman H; Department of Microbiology, Abdul Wali Khan University, Mardan 23200, KP, Pakistan.
Qasim M; Department of Microbiology, Kohat University of Science and Technology, Kohat 26000, KP, Pakistan.
Akram MS; National Horizons Centre, Teesside University, Darlington DL11HG, UK.; School of Health & Life Sciences, Teesside University, Middlesbrough TS1 3BX, UK.
Saygideger Y; Department of Pulmonary, Cukurova University School of Medicine, 01330 Adana, Turkey.; Department of Translational Medicine, Institute of Health Sciences, Cukurova University, 01330 Adana, Turkey.
Puspita N; National Horizons Centre, Teesside University, Darlington DL11HG, UK.
Saygıdeğer Demir B; Department of Biotechnology, Institute of Natural and Applied Sciences, Cukurova University, 01330 Adana, Turkey.
Alzahrani KJ; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Rehman MFU; Institute of Chemistry, University of Sargodha, Sargodha 40100, Pakistan.
Alzahrani FM; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Alblihd MA; Department of Medical Microbiology, College of Medicine, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
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Źródło:
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2022 Aug 28; Vol. 58 (9). Date of Electronic Publication: 2022 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
Gastritis*/microbiology
Helicobacter Infections*/microbiology
Helicobacter pylori*
Hydrogenase*/metabolism
Nucleoside-Diphosphate Kinase*/metabolism
Stomach Neoplasms*/pathology
Glycogen Synthase/metabolism ; Humans ; Pakistan ; Peroxiredoxins/metabolism ; Proteome/metabolism ; Proteomics ; Tandem Mass Spectrometry ; Ulcer
Czasopismo naukowe
Tytuł:
Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP-deficient lung cancer.
Autorzy:
Chang WH; Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen YJ; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.
Hsiao YJ; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chiang CC; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wang CY; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chang YL; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hong QS; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin CY; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan.
Lin SU; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chang GC; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chen HY; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan.
Chen YJ; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.
Chen CH; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of California Davis, Davis, CA, USA.; Division of Nephrology, Department of Internal Medicine, University of California Davis, Davis, CA, USA.; Comprehensive Cancer Center, University of California Davis, Davis, CA, USA.
Yang PC; Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yu SL; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Institute of Medical Device and Imaging, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
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Źródło:
EMBO reports [EMBO Rep] 2022 Aug 03; Vol. 23 (8), pp. e54265. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Lung Neoplasms*/genetics
Purine-Nucleoside Phosphorylase*/metabolism
Humans ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism ; Vimentin/genetics
Czasopismo naukowe
Tytuł:
Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium.
Autorzy:
Narczyk M; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland.
Wojtyś MI; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland.; Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Leščić Ašler I; Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Žinić B; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Luić M; Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Jagusztyn-Krynicka EK; Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Štefanić Z; Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Bzowska A; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1083-1097.
Typ publikacji:
Journal Article
MeSH Terms:
Helicobacter pylori*
Purine-Nucleoside Phosphorylase*/chemistry
Purine-Nucleoside Phosphorylase*/metabolism
Binding Sites ; Cell Culture Techniques ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Purines/chemistry ; Purines/pharmacology
Czasopismo naukowe
Tytuł:
Whole-cell biosynthesis of cytarabine by an unnecessary protein-reduced Escherichia coli that coexpresses purine and uracil phosphorylase.
Autorzy:
Ping L; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Ruxian J; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Mengping Z; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Pei J; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Zhuoya L; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Guosheng L; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Zhenyu W; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.
Hailei W; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, China.; Advanced Environmental Biotechnology Center, Nanyang Technological University, Singapore, Singapore.
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Źródło:
Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Jul; Vol. 119 (7), pp. 1768-1780. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/metabolism
Purine-Nucleoside Phosphorylase*/chemistry
Purine-Nucleoside Phosphorylase*/genetics
Purine-Nucleoside Phosphorylase*/metabolism
Cytarabine/metabolism ; Phosphorylases/metabolism ; Purines/metabolism ; Uracil/metabolism
Czasopismo naukowe
Tytuł:
Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Autorzy:
Wen Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, RNA Biomedical Institute, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Li X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, RNA Biomedical Institute, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Guo W; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, RNA Biomedical Institute, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Wu B; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, RNA Biomedical Institute, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
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Źródło:
Proteins [Proteins] 2022 Jun; Vol. 90 (6), pp. 1233-1241. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleosides*/metabolism
Purine-Nucleoside Phosphorylase*/chemistry
Purine-Nucleoside Phosphorylase*/genetics
Purine-Nucleoside Phosphorylase*/metabolism
Escherichia coli/metabolism ; Pyrimidine Phosphorylases/metabolism ; Pyrimidines ; Substrate Specificity
Czasopismo naukowe
Tytuł:
MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells.
Autorzy:
Yang J; Department of Radiology, Peking University Shenzhen Hospital, China.
Li Z; Intervention and Cell Therapy Center, Peking University Shenzhen Hospital, China.
Pang Y; Department of Minimally Invasive Intervention, Peking University Shenzhen Hospital, China.
Zhou T; Intervention and Cell Therapy Center, Peking University Shenzhen Hospital, China.
Sun J; Intervention and Cell Therapy Center, Peking University Shenzhen Hospital, China.; Shenzhen Beike Biotechnology Research Institute, China.
Cheng XY; Department of Minimally Invasive Intervention, Peking University Shenzhen Hospital, China.
Zheng WV; Intervention and Cell Therapy Center, Peking University Shenzhen Hospital, China.
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Źródło:
Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2022 Jun; Vol. 31 (6), pp. 655-670.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Liver Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
NM23 Nucleoside Diphosphate Kinases*/genetics
NM23 Nucleoside Diphosphate Kinases*/metabolism
Cell Line ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans
Czasopismo naukowe
Tytuł:
Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons.
Autorzy:
Tsui M; Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Institute of Medical Sciences, The University to Toronto, Toronto, ON, Canada.
Biro J; Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Chan J; Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Min W; Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Dobbs K; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.
Grunebaum E; Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada. .; The Institute of Medical Sciences, The University to Toronto, Toronto, ON, Canada. .; Division of Immunology and Allergy, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G1X8, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 31; Vol. 12 (1), pp. 9084. Date of Electronic Publication: 2022 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
MeSH Terms:
Apoptosis*
Induced Pluripotent Stem Cells*/cytology
Neurons*/cytology
Purine-Nucleoside Phosphorylase*/deficiency
Purine-Nucleoside Phosphorylase*/metabolism
Tumor Suppressor Protein p53*/genetics
Humans ; Primary Immunodeficiency Diseases ; Purine-Pyrimidine Metabolism, Inborn Errors
SCR Disease Name:
Purine Nucleoside Phosphorylase Deficiency
Czasopismo naukowe
Tytuł:
Control of a pyrimidine ribonucleotide salvage pathway in Pseudomonas oleovorans.
Autorzy:
Gill R; Department of Chemistry, Texas A&M University-Commerce, Commerce, TX, 75429, USA.
West TP; Department of Chemistry, Texas A&M University-Commerce, Commerce, TX, 75429, USA. .
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Źródło:
Archives of microbiology [Arch Microbiol] 2022 Jun 10; Vol. 204 (7), pp. 383. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Nucleoside Deaminases*/metabolism
Pseudomonas oleovorans*
Ammonium Sulfate ; Carbon ; Cytosine Deaminase ; Humans ; Nitrogen ; Pyrimidine Nucleotides ; Pyrimidines/metabolism ; Ribonucleotides ; Succinic Acid/metabolism ; Uracil/metabolism
Czasopismo naukowe

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