Temat: "Nucleoside-Phosphate Kinase" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders.
Autorzy:: Frisk JH; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Örn S; Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Pejler G; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Eriksson S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Wang L; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden. .; Pokaż więcej
Źródło:: BMC neuroscience [BMC Neurosci] 2022 Mar 27; Vol. 23 (1), pp. 19. Date of Electronic Publication: 2022 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: Neurodegenerative Diseases*/genetics
Nucleoside-Phosphate Kinase*/genetics
Zebrafish*/metabolism
Animals ; Mutation ; Phosphorylation ; Thymidine Kinase/metabolism

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Skocz do pozycji: 2.

Tytuł:: Structural and functional analysis of human thymidylate kinase isoforms.
Autorzy:: Hu Frisk J; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Pejler G; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Eriksson S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Wang L; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Pokaż więcej
Źródło:: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2022; Vol. 41 (3), pp. 321-332. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:: Journal Article
MeSH Terms:: Nucleoside-Phosphate Kinase*/chemistry
Catalysis ; Humans ; Phosphorylation ; Protein Isoforms/genetics ; Protein Isoforms/metabolism

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Skocz do pozycji: 3.

Tytuł:: MiR-494-3p alleviates acute lung injury through regulating NLRP3 activation by targeting CMPK2.
Autorzy:: Wang H; Operating Room, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China.
Wang S; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China.
Huang S; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China.; Pokaż więcej
Źródło:: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Jun; Vol. 99 (3), pp. 286-295. Date of Electronic Publication: 2021 May 26.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Lung Injury/*prevention & control
MicroRNAs/*genetics
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Nucleoside-Phosphate Kinase/*metabolism
Acute Lung Injury/chemically induced ; Acute Lung Injury/metabolism ; Acute Lung Injury/pathology ; Animals ; Humans ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Nucleoside-Phosphate Kinase/genetics

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Skocz do pozycji: 4.

Tytuł:: 1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors.
Autorzy:: Jian Y; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.
Hulpia F; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.
D P Risseeuw M; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.
Forbes HE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Caljon G; Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp, Universiteitsplein 1 (S7), B-2610 Wilrijk, Belgium.
Munier-Lehmann H; Unit of Chemistry and Biocatalysis, Department of Structural Biology and Chemistry, Institut Pasteur, CNRS UMR3523, 28 Rue du Dr. Roux, CEDEX 15 75724 Paris, France.
I M Boshoff H; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Van Calenbergh S; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 17; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antitubercular Agents*/chemical synthesis
Antitubercular Agents*/chemistry
Antitubercular Agents*/pharmacology
Enzyme Inhibitors*/chemical synthesis
Enzyme Inhibitors*/chemistry
Enzyme Inhibitors*/pharmacology
Thymine*/analogs & derivatives
Thymine*/chemical synthesis
Thymine*/chemistry
Thymine*/pharmacology
Bacterial Proteins/*antagonists & inhibitors
Mycobacterium tuberculosis/*enzymology
Nucleoside-Phosphate Kinase/*antagonists & inhibitors
Bacterial Proteins/metabolism ; Humans ; Models, Molecular ; Molecular Structure ; Nucleoside-Phosphate Kinase/metabolism ; Structure-Activity Relationship

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Skocz do pozycji: 5.

Tytuł:: 1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase.
Autorzy:: Jian Y; Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Risseeuw MDP; Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Froeyen M; Department of Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Song L; Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Cappoen D; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Cos P; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Munier-Lehmann H; Unit of Chemistry and Biocatalysis, Department of Structural Biology and Chemistry, Institut Pasteur, CNRS UMR3523, Paris, France.
van Calenbergh S; Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2019 Dec; Vol. 34 (1), pp. 1730-1739.
Typ publikacji:: Journal Article
MeSH Terms:: Amides/*pharmacology
Antitubercular Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Mycobacterium tuberculosis/*drug effects
Nucleoside-Phosphate Kinase/*antagonists & inhibitors
Thymine/*pharmacology
Amides/chemical synthesis ; Amides/chemistry ; Antitubercular Agents/chemical synthesis ; Antitubercular Agents/chemistry ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Microbial Sensitivity Tests ; Molecular Structure ; Mycobacterium tuberculosis/enzymology ; Nucleoside-Phosphate Kinase/metabolism ; Structure-Activity Relationship ; Thymine/chemical synthesis ; Thymine/chemistry

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Skocz do pozycji: 6.

Tytuł:: Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Autorzy:: Walter P; Unité de Chimie et Biocatalyse, Département de Biologie Structurale et Chimie, Institut Pasteur, CNRS UMR3523, Paris, France.
Mechaly A; Plate-Forme de Cristallographie, C2RT, Institut Pasteur, CNRS UMR3528, Paris, France.
Bous J; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Haouz A; Plate-Forme de Cristallographie, C2RT, Institut Pasteur, CNRS UMR3528, Paris, France.
England P; Plate-Forme de Biophysique Moléculaire, C2RT, Institut Pasteur, CNRS UMR3528, Paris, France.
Lai-Kee-Him J; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Ancelin A; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Hoos S; Plate-Forme de Biophysique Moléculaire, C2RT, Institut Pasteur, CNRS UMR3528, Paris, France.
Baron B; Plate-Forme de Biophysique Moléculaire, C2RT, Institut Pasteur, CNRS UMR3528, Paris, France.
Trapani S; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Bron P; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Labesse G; Centre de Biologie Structurale (CBS), Univ Montpellier, INSERM, CNRS, Montpellier, France.
Munier-Lehmann H; Unité de Chimie et Biocatalyse, Département de Biologie Structurale et Chimie, Institut Pasteur, CNRS UMR3523, Paris, France.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2022 Aug; Vol. 289 (16), pp. 4869-4887. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Bacterial Agents*/pharmacology
Gram-Positive Bacteria*
Adenosine Triphosphate ; Allosteric Regulation ; Amino Acid Sequence ; Cryoelectron Microscopy ; Guanosine Triphosphate/pharmacology ; Humans ; Nucleoside-Phosphate Kinase ; Uridine Monophosphate/pharmacology ; Uridine Triphosphate/pharmacology

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Skocz do pozycji: 7.

Tytuł:: The structural basis of unique substrate recognition by Plasmodium thymidylate kinase: Molecular dynamics simulation and inhibitory studies.
Autorzy:: Kandeel M; Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, King Faisal University, Hofuf, Alahsa, Saudi Arabia.; Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Kafrelsheikh, Egypt.
Kitade Y; Department of Applied Chemistry, Faculty of Engineering, Aichi Institute of Technology, Yachigusa, Yakuza, Toyota, Japan.; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido, Gifu, Japan.
Al-Taher A; Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, King Faisal University, Hofuf, Alahsa, Saudi Arabia.
Al-Nazawi M; Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, King Faisal University, Hofuf, Alahsa, Saudi Arabia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Feb 07; Vol. 14 (2), pp. e0212065. Date of Electronic Publication: 2019 Feb 07 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Molecular Dynamics Simulation*
Nucleoside-Phosphate Kinase/*metabolism
Plasmodium falciparum/*enzymology
Protozoan Proteins/*metabolism
Binding Sites ; Deoxyguanosine/chemistry ; Deoxyguanosine/metabolism ; Hydrogen Bonding ; Ligands ; Nucleoside-Phosphate Kinase/antagonists & inhibitors ; Nucleoside-Phosphate Kinase/chemistry ; Protein Structure, Tertiary ; Protozoan Proteins/antagonists & inhibitors ; Protozoan Proteins/chemistry ; Substrate Specificity

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Skocz do pozycji: 8.

Tytuł:: UMP Kinase Regulates Chloroplast Development and Cold Response in Rice.
Autorzy:: Dong Q; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Zhang YX; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Zhou Q; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Liu QE; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Chen DB; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Wang H; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Cheng SH; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Cao LY; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .
Shen XH; State Key Laboratory of Rice Biology and Key Laboratory for Zhejiang Super Rice Research, China National Rice Research Institute, Hangzhou 310006, China. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Apr 29; Vol. 20 (9). Date of Electronic Publication: 2019 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Cold-Shock Response*/genetics
Plant Development*/genetics
Chloroplasts/*physiology
Nucleoside-Phosphate Kinase/*metabolism
Oryza/*physiology
Cloning, Molecular ; Gene Expression Regulation, Plant ; Mutation ; Nucleoside-Phosphate Kinase/genetics ; Phenotype ; Plastids/genetics ; Transcription, Genetic

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Skocz do pozycji: 9.

Tytuł:: Immuno-diagnosis of Mycobacterium tuberculosis in sputum, and reduction of timelines for its positive cultures to within 3 h by pathogen-specific thymidylate kinase expression assays.
Autorzy:: Wayengera M; Unit of Genetics & Genomics, Dept. of Pathology, School of Biomedical Science, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda. .; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda. .; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda. .
Mwebaza I; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Welishe J; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Bayiyana A; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Kateete DP; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Wampande E; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Kirimunda S; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Kigozi E; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Katabazi F; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Musubika C; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Kyobe S; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Babirye P; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Asiimwe B; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.
Joloba ML; Dept of Immunology/Molecular Biology (Mycobacteriology Laboratory), School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Dept. of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, P o Box 7072, Kampala, Uganda.; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2017 Aug 08; Vol. 10 (1), pp. 368. Date of Electronic Publication: 2017 Aug 08.
Typ publikacji:: Journal Article
MeSH Terms:: Immunoenzyme Techniques*
Antigens, Bacterial/*analysis
Mycobacterium tuberculosis/*isolation & purification
Nucleoside-Phosphate Kinase/*analysis
Reverse Transcriptase Polymerase Chain Reaction/*methods
Tuberculosis, Pulmonary/*diagnosis
Adult ; Antibodies/chemistry ; Antigens, Bacterial/genetics ; Antigens, Bacterial/immunology ; Coinfection ; Female ; Gene Expression ; HIV/physiology ; HIV Infections/diagnosis ; HIV Infections/virology ; Humans ; Limit of Detection ; Male ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/immunology ; Nucleoside-Phosphate Kinase/genetics ; Nucleoside-Phosphate Kinase/immunology ; Recombinant Proteins/analysis ; Recombinant Proteins/genetics ; Recombinant Proteins/immunology ; Sputum/microbiology ; Time Factors ; Tuberculosis, Pulmonary/microbiology

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Skocz do pozycji: 10.

Tytuł:: Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.
Autorzy:: Biswas A; Department of Physics, Indian Institute of Science, Bangalore, India.
Shukla A; Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.
Chaudhary SK; Department of Physics, Indian Institute of Science, Bangalore, India.
Santhosh R; Department of Bioinformatics, Alagappa University, Karaikudi, India.
Jeyakanthan J; Department of Bioinformatics, Alagappa University, Karaikudi, India.
Sekar K; Department of Computational and Data Sciences, Indian Institute of Science, Bangalore, India.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2017 Aug; Vol. 284 (15), pp. 2527-2544. Date of Electronic Publication: 2017 Jul 13.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Molecular*
Bacteria, Thermoduric/*enzymology
Bacterial Proteins/*metabolism
Nucleoside-Phosphate Kinase/*metabolism
Amino Acid Sequence ; Amino Acid Substitution ; Apoenzymes/chemistry ; Apoenzymes/genetics ; Apoenzymes/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Biocatalysis ; Catalytic Domain ; Crystallography, X-Ray ; Enzyme Stability ; Holoenzymes/chemistry ; Holoenzymes/genetics ; Holoenzymes/metabolism ; Ligands ; Mutagenesis, Site-Directed ; Mutation ; Nucleoside-Phosphate Kinase/chemistry ; Nucleoside-Phosphate Kinase/genetics ; Protein Conformation ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Ribonucleotides/chemistry ; Ribonucleotides/metabolism ; Sequence Alignment ; Substrate Specificity

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Skocz do pozycji: 11.

Tytuł:: Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase.
Autorzy:: Hu Frisk J; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Pejler G; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Eriksson S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Wang L; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Pokaż więcej
Źródło:: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2022; Vol. 41 (12), pp. 1305-1317. Date of Electronic Publication: 2022 Mar 28.
Typ publikacji:: Journal Article
MeSH Terms:: Mesorhizobium*/metabolism
Metals, Heavy*/toxicity
Metals, Heavy*/metabolism
Humans ; Nucleoside-Phosphate Kinase
SCR Organism:: Mesorhizobium delmotii

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Skocz do pozycji: 12.

Tytuł:: Cell polarity and cell adhesion associated gene expression differences between invasive micropapillary and no special type breast carcinomas and their prognostic significance.
Autorzy:: Kramer Z; 2nd Department of Pathology, Semmelweis University, Üllői Street 93, Budapest, 1091, Hungary.
Kenessey I; 2nd Department of Pathology, Semmelweis University, Üllői Street 93, Budapest, 1091, Hungary.
Gángó A; 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői Street 26, Budapest, 1085, Hungary.
Lendvai G; 2nd Department of Pathology, Semmelweis University, Üllői Street 93, Budapest, 1091, Hungary.
Kulka J; 2nd Department of Pathology, Semmelweis University, Üllői Street 93, Budapest, 1091, Hungary. .
Tőkés AM; 2nd Department of Pathology, Semmelweis University, Üllői Street 93, Budapest, 1091, Hungary.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 16; Vol. 11 (1), pp. 18484. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Adhesion*
Cell Polarity*
Transcriptome*
Breast Neoplasms/*metabolism
Carcinoma/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Carcinoma/genetics ; Carcinoma/pathology ; Claudin-3/genetics ; Claudin-3/metabolism ; Epithelial-Mesenchymal Transition ; Female ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Middle Aged ; Neoplasm Invasiveness ; Nucleoside-Phosphate Kinase/genetics ; Nucleoside-Phosphate Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Survival Analysis ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 13.

Tytuł:: Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Autorzy:: Javorsky A; Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Vic, Australia.
Humbert PO; Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Vic, Australia. .; Research Centre for Molecular Cancer Prevention, La Trobe University, Melbourne, Vic, Australia. .; Department of Biochemistry & Molecular Biology, University of Melbourne, Melbourne, Vic, Australia. .; Department of Clinical Pathology, University of Melbourne, Melbourne, Vic, Australia. .
Kvansakul M; Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Vic, Australia. .; Research Centre for Molecular Cancer Prevention, La Trobe University, Melbourne, Vic, Australia. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Jun 11; Vol. 4 (1), pp. 724. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji:: Journal Article
MeSH Terms:: PDZ Domains*
Coronavirus Envelope Proteins/*chemistry
Coronavirus Envelope Proteins/*metabolism
Membrane Proteins/*chemistry
Membrane Proteins/*metabolism
Nucleoside-Phosphate Kinase/*chemistry
Nucleoside-Phosphate Kinase/*metabolism
Amino Acid Sequence ; Humans ; Models, Molecular ; Protein Binding

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Skocz do pozycji: 14.

Tytuł:: UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis.
Autorzy:: Kim H; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Subbannayya Y; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Humphries F; Program in Innate Immunity, University of Massachusetts Medical School, Worcester, MA, United States of America.
Skejsol A; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Pinto SM; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Giambelluca M; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Espevik T; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Fitzgerald KA; Program in Innate Immunity, University of Massachusetts Medical School, Worcester, MA, United States of America.
Kandasamy RK; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Oct 27; Vol. 16 (10), pp. e0258989. Date of Electronic Publication: 2021 Oct 27 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression/*immunology
Interferon Regulatory Factor-3/*immunology
Macrophages/*metabolism
Nucleoside-Phosphate Kinase/*immunology
Receptor, Interferon alpha-beta/*immunology
Animals ; Humans ; Macrophages/cytology ; Mice ; Mice, Knockout ; THP-1 Cells

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Skocz do pozycji: 15.

Tytuł:: Corneal curvature-associated MTOR variant differentiates mild myopia from high myopia in Han Chinese population.
Autorzy:: Yuan XL; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.; Shantou University Medical College, Shantou, Guangdong, China.
Zhang R; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Zheng Y; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Sun L; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Wang G; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Chen S; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Xu Y; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Chen SL; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Qiu K; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Ng TK; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.; Shantou University Medical College, Shantou, Guangdong, China.; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Pokaż więcej
Źródło:: Ophthalmic genetics [Ophthalmic Genet] 2021 Aug; Vol. 42 (4), pp. 446-457. Date of Electronic Publication: 2021 May 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Asian People/*genetics
Cornea/*pathology
Myopia, Degenerative/*diagnosis
Myopia, Degenerative/*genetics
TOR Serine-Threonine Kinases/*genetics
Adult ; Aged ; Alleles ; Axial Length, Eye ; Biometry ; China/epidemiology ; Eye Proteins/genetics ; Female ; Genetic Association Studies ; Genetic Markers ; Genome-Wide Association Study ; Genotyping Techniques ; Humans ; Male ; Middle Aged ; Myopia/diagnosis ; Myopia/genetics ; Nucleoside-Phosphate Kinase/genetics ; Polymorphism, Single Nucleotide ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Refraction, Ocular ; Retinol-Binding Proteins/genetics ; Wnt Proteins/genetics ; Young Adult

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Skocz do pozycji: 16.

Tytuł:: Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.
Autorzy:: Meinsma R; a Academic Medical Center, Laboratory Genetic Metabolic Diseases , Amsterdam , The Netherlands.
van Kuilenburg AB; a Academic Medical Center, Laboratory Genetic Metabolic Diseases , Amsterdam , The Netherlands.; Pokaż więcej
Źródło:: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2016 Dec; Vol. 35 (10-12), pp. 613-618.
Typ publikacji:: Journal Article
MeSH Terms:: Nucleoside-Phosphate Kinase/*genetics
Uridine Kinase/*genetics
Adenosine Triphosphate/chemistry ; Cytidine/chemistry ; Escherichia coli ; Gene Expression ; Humans ; Kinetics ; Neuroblastoma/enzymology ; Nucleoside-Phosphate Kinase/biosynthesis ; Nucleoside-Phosphate Kinase/chemistry ; Substrate Specificity ; Uridine/chemistry ; Uridine Kinase/biosynthesis ; Uridine Kinase/chemistry

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Skocz do pozycji: 17.

Tytuł:: Genome sequence of Perigonia lusca single nucleopolyhedrovirus: insights into the evolution of a nucleotide metabolism enzyme in the family Baculoviridae.
Autorzy:: Ardisson-Araújo DM; Laboratory of Baculovirus, Cell Biology Department, University of Brasília, Brasília, DF, Brazil.; Division of Biology, Kansas State University, Manhattan, KS, USA.
Lima RN; Laboratory of Baculovirus, Cell Biology Department, University of Brasília, Brasília, DF, Brazil.
Melo FL; Laboratory of Baculovirus, Cell Biology Department, University of Brasília, Brasília, DF, Brazil.
Clem RJ; Division of Biology, Kansas State University, Manhattan, KS, USA.
Huang N; Division of Biology, Kansas State University, Manhattan, KS, USA.
Báo SN; Laboratory of Baculovirus, Cell Biology Department, University of Brasília, Brasília, DF, Brazil.
Sosa-Gómez DR; Embrapa Soja, Londrina, PR, Brazil.
Ribeiro BM; Laboratory of Baculovirus, Cell Biology Department, University of Brasília, Brasília, DF, Brazil.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jun 07; Vol. 6, pp. 24612. Date of Electronic Publication: 2016 Jun 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Viral*
Nucleopolyhedroviruses/*genetics
Nucleoside-Phosphate Kinase/*metabolism
Pyrophosphatases/*metabolism
Viral Proteins/*metabolism
Animals ; Base Sequence ; Binding Sites ; DNA, Viral/chemistry ; DNA, Viral/isolation & purification ; DNA, Viral/metabolism ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Microscopy, Confocal ; Microscopy, Electron, Scanning ; Nucleopolyhedroviruses/classification ; Nucleopolyhedroviruses/physiology ; Nucleoside-Phosphate Kinase/chemistry ; Nucleoside-Phosphate Kinase/genetics ; Nucleotides/biosynthesis ; Nucleotides/chemistry ; Open Reading Frames/genetics ; Phylogeny ; Protein Structure, Tertiary ; Pyrophosphatases/chemistry ; Pyrophosphatases/genetics ; Sequence Alignment ; Sequence Analysis, DNA ; Sf9 Cells ; Spodoptera ; Tandem Repeat Sequences/genetics ; Viral Proteins/genetics ; Virus Replication

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Skocz do pozycji: 18.

Tytuł:: Enhancement of Nucleoside Production in Hirsutella sinensis Based on Biosynthetic Pathway Analysis.
Autorzy:: Liu ZQ; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Zhang B; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Lin S; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Baker PJ; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Chen MS; Department of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
Xue YP; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Wu H; East China Pharmaceutical Group Limited Co., Ltd, Hangzhou 311000, China.
Xu F; East China Pharmaceutical Group Limited Co., Ltd, Hangzhou 311000, China.
Yuan SJ; East China Pharmaceutical Group Limited Co., Ltd, Hangzhou 311000, China.
Teng Y; East China Pharmaceutical Group Limited Co., Ltd, Hangzhou 311000, China.
Wu LF; East China Pharmaceutical Group Limited Co., Ltd, Hangzhou 311000, China.
Zheng YG; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 2520347. Date of Electronic Publication: 2017 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: Biosynthetic Pathways/*genetics
Nucleoside-Phosphate Kinase/*genetics
Nucleosides/*biosynthesis
Carbon-Nitrogen Ligases/genetics ; Carbon-Nitrogen Ligases/metabolism ; Hypocreales ; Nucleoside-Phosphate Kinase/metabolism ; Purines/biosynthesis ; Pyrimidines/biosynthesis ; Uridine/biosynthesis

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Skocz do pozycji: 19.

Tytuł:: Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of Bis(Indolyl)Pyridines Analogues of the Marine Alkaloid Nortopsentin.
Autorzy:: Abo-Salem HM; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.
Abd El Salam HA; Green Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt.
Abdel-Aziem AM; Chemistry Department, Faculty of Science (Girl's Branch), Al-Azhar University, Cairo 11284, Egypt.
Abdel-Aziz MS; Microbial Chemistry Department, Genetic Engineering and biotechnology Division, National Research Centre, Dokki, Giza 12622, Egypt.
El-Sawy ER; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jul 06; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids/*chemistry
Anti-Bacterial Agents/*chemical synthesis
Anti-Bacterial Agents/*pharmacology
Bacteria/*drug effects
Biofilms/*growth & development
Enzyme Inhibitors/*pharmacology
Indoles/*chemistry
Biofilms/drug effects ; DNA Gyrase/chemistry ; DNA Topoisomerase IV/antagonists & inhibitors ; Enzyme Inhibitors/chemistry ; Molecular Docking Simulation ; Nucleoside-Phosphate Kinase/antagonists & inhibitors ; Pyridines/chemistry

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Skocz do pozycji: 20.

Tytuł:: Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6.
Autorzy:: Lüttgenau SM; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Emming C; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Wagner T; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Harms J; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Guske J; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Weber K; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Neugebauer U; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Schröter R; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Panichkina O; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Pethő Z; Institute of Physiology, University of Münster, Münster, Germany.
Weber F; Institute for Pathology, University of Regensburg, Regensburg, Germany.
Schwab A; Institute of Physiology, University of Münster, Münster, Germany.
Wege AK; Department of Gynaecology and Obstetrics, University Medical Centre Regensburg, Regensburg, Germany.
Nedvetsky P; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany.
Krahn MP; Department of Medical Cell Biology, Medical Clinic D, University Hospital of Münster, Albert-Schweitzer-Campus 1-A14, 48149, Münster, Germany. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2021 May 04; Vol. 20 (1), pp. 74. Date of Electronic Publication: 2021 May 04.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: ADP-Ribosylation Factor 6/*metabolism
Colorectal Neoplasms/*pathology
Membrane Proteins/*metabolism
Nucleoside-Phosphate Kinase/*metabolism
rac1 GTP-Binding Protein/*metabolism
Animals ; Cell Movement/physiology ; HCT116 Cells ; Heterografts ; Humans ; Mice ; Neoplasm Invasiveness/pathology

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