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Wyszukujesz frazę ""Nucleotidyltransferases"" wg kryterium: Temat


Tytuł :
Phosphorylation and chromatin tethering prevent cGAS activation during mitosis.
Autorzy :
Li T; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Huang T; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Du M; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Chen X; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Du F; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Ren J; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Chen ZJ; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA. .; Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Mar 19; Vol. 371 (6535). Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Chromatin/*metabolism
Nucleotidyltransferases/*metabolism
Aurora Kinase B/metabolism ; Cell Cycle ; Cell Line ; DNA/metabolism ; DNA, Mitochondrial/metabolism ; Enzyme Activation ; Humans ; Nucleotides, Cyclic/metabolism ; Nucleotidyltransferases/chemistry ; Phosphorylation ; Protein Multimerization
Czasopismo naukowe
Tytuł :
Saccharomyces cerevisiae RNA lariat debranching enzyme, Dbr1p, is required for completion of reverse transcription by the retrovirus-like element Ty1 and cleaves branched Ty1 RNAs.
Autorzy :
Menees TM; School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, MO, USA. .
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2021 Mar; Vol. 296 (2), pp. 409-422. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Reverse Transcription*
RNA Nucleotidyltransferases/*genetics
Saccharomyces cerevisiae/*enzymology
DNA, Single-Stranded/metabolism ; HIV-1/genetics ; Mutation ; RNA Nucleotidyltransferases/metabolism ; Retroelements ; Saccharomyces cerevisiae/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Silencing of UAP1L1 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma.
Autorzy :
Xiao X; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jiang L; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Hu H; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Huang Y; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Yang L; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Jiao Y; Department of Thoracic Surgery, Zhangjiajie City People's Hospital, Zhangjiajie, Hunan, China.
Wei G; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2021 Mar; Vol. 60 (3), pp. 179-187. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms/*pathology
Esophageal Squamous Cell Carcinoma/*pathology
Nucleotidyltransferases/*genetics
Aged ; Animals ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Esophageal Neoplasms/genetics ; Esophageal Squamous Cell Carcinoma/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Humans ; Male ; Mice, Nude ; Middle Aged ; Nucleotidyltransferases/metabolism ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs.
Autorzy :
Ketkar A; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Smith L; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Johnson C; Arkansas School for Mathematics, Sciences, and the Arts, Hot Springs, AR 71901, USA.
Richey A; Arkansas School for Mathematics, Sciences, and the Arts, Hot Springs, AR 71901, USA.
Berry M; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Hartman JH; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.
Maddukuri L; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Reed MR; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Gunderson JEC; Department of Physics, Hendrix College, Conway, AR 72032, USA.
Leung JWC; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Eoff RL; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Feb 26; Vol. 49 (4), pp. 2065-2084.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Replication*
G-Quadruplexes*
DNA/*chemistry
DNA/*metabolism
Nucleotidyltransferases/*chemistry
Nucleotidyltransferases/*metabolism
Cell Line ; DNA-Directed DNA Polymerase/metabolism ; Genes, myc ; Humans ; Models, Molecular ; Mutation ; Nucleotide Motifs ; Nucleotidyltransferases/genetics ; Protein Binding
Czasopismo naukowe
Tytuł :
Phosphopantetheine Adenylyltransferase: A promising drug target to combat antibiotic resistance.
Autorzy :
Gupta A; Department of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.
Sharma P; Department of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.
Singh TP; Department of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address: .
Sharma S; Department of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2021 Feb; Vol. 1869 (2), pp. 140566. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Coenzyme A/*chemistry
Drug Resistance, Bacterial/*genetics
Nucleotidyltransferases/*chemistry
Coenzyme A/ultrastructure ; Crystallography, X-Ray ; Humans ; Nucleotidyltransferases/genetics ; Nucleotidyltransferases/ultrastructure ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Conformational dynamics is critical for the allosteric inhibition of cGAS upon acetyl-mimic mutations.
Autorzy :
Guo J; College of Life Sciences, Nanjing Agricultural University, Nanjing, 210095, China. .
Li M
Zhang Y
Xi L
Cui F
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Źródło :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2021 Jan 28; Vol. 23 (3), pp. 2154-2165.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Nucleotidyltransferases/*antagonists & inhibitors
Nucleotidyltransferases/*genetics
Allosteric Regulation ; DNA/metabolism ; Humans ; Molecular Dynamics Simulation ; Mutation ; Nucleotides, Cyclic/metabolism ; Nucleotidyltransferases/metabolism ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
Inhibition of d-glycero-β-d-manno-heptose 1-phosphate adenylyltransferase from Burkholderia pseudomallei by epigallocatechin gallate and myricetin.
Autorzy :
Kim S; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52, Ewhayeodae-gil, Seoul 03760, Korea.
Jo S; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52, Ewhayeodae-gil, Seoul 03760, Korea.
Kim MS; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52, Ewhayeodae-gil, Seoul 03760, Korea.
Kam H; Department of Pharmacy, Ewha Womans University, 52, Ewhayeodae-gil, Seoul 03760, Korea.
Shin DH; Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52, Ewhayeodae-gil, Seoul 03760, Korea.
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Źródło :
The Biochemical journal [Biochem J] 2021 Jan 15; Vol. 478 (1), pp. 235-245.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Burkholderia pseudomallei/*enzymology
Flavonoids/*chemistry
Mannose/*chemistry
Nucleotidyltransferases/*chemistry
Pyrans/*chemistry
Adenosine Triphosphate/chemistry ; Catechin/analogs & derivatives ; Catechin/chemistry ; Crystallography, X-Ray ; Escherichia coli/metabolism ; Inhibitory Concentration 50 ; Kinetics ; Ligands ; Molecular Docking Simulation ; Nucleotidyltransferases/antagonists & inhibitors ; Nucleotidyltransferases/metabolism
Czasopismo naukowe
Tytuł :
Heterologous Expression and Characterization of Flavinadenine Dinucleotide Synthetase from Candida famata for Flavin Adenine Dinucleotide Production.
Autorzy :
Zhou G; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou-310014, China.
Pan Q; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou-310014, China.
Hu Z; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou-310014, China.
Qiu J; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou-310014, China.
Yu Z; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou-310014, China.
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Źródło :
Protein and peptide letters [Protein Pept Lett] 2021; Vol. 28 (2), pp. 229-239.
Typ publikacji :
Journal Article
MeSH Terms :
Candida/*enzymology
Escherichia coli/*metabolism
Flavin Mononucleotide/*metabolism
Flavin-Adenine Dinucleotide/*metabolism
Nucleotidyltransferases/*metabolism
Recombinant Proteins/*metabolism
Amino Acid Sequence ; Escherichia coli/genetics ; Escherichia coli/growth & development ; Nucleotidyltransferases/chemistry ; Nucleotidyltransferases/genetics ; Phylogeny ; Protein Conformation ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Sequence Homology
Czasopismo naukowe
Tytuł :
Regulation and inhibition of the DNA sensor cGAS.
Autorzy :
Hertzog J; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Rehwinkel J; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
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Źródło :
EMBO reports [EMBO Rep] 2020 Dec 03; Vol. 21 (12), pp. e51345. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Membrane Proteins*/genetics
Nucleotidyltransferases*/genetics
Nucleotidyltransferases*/metabolism
Cytokines ; DNA/genetics ; Humans ; Signal Transduction
Czasopismo naukowe
Tytuł :
The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis.
Autorzy :
Scheer H; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
de Almeida C; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Ferrier E; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Simonnot Q; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Poirier L; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Pflieger D; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Sement FM; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Koechler S; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Piermaria C; Plateforme Protéomique Strasbourg Esplanade du CNRS, Université de Strasbourg, Strasbourg, France.
Krawczyk P; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, Warsaw, Poland.
Mroczek S; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, Warsaw, Poland.
Chicher J; Plateforme Protéomique Strasbourg Esplanade du CNRS, Université de Strasbourg, Strasbourg, France.
Kuhn L; Plateforme Protéomique Strasbourg Esplanade du CNRS, Université de Strasbourg, Strasbourg, France.
Dziembowski A; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, Warsaw, Poland.
Hammann P; Plateforme Protéomique Strasbourg Esplanade du CNRS, Université de Strasbourg, Strasbourg, France.
Zuber H; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France. .
Gagliardi D; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 26; Vol. 12 (1), pp. 1298. Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
RNA Nucleotidyltransferases/*metabolism
RNA, Small Interfering/*metabolism
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Co-Repressor Proteins/metabolism ; DEAD-box RNA Helicases/metabolism ; Gene Expression Regulation, Plant ; Humans ; Proto-Oncogene Proteins/metabolism ; RNA Nucleotidyltransferases/genetics ; RNA Stability/genetics ; RNA, Messenger/metabolism ; Ribonucleoproteins/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Tobacco/genetics ; Transcriptome ; Uridine/metabolism
Czasopismo naukowe
Tytuł :
cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing.
Autorzy :
Zhou W; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Mohr L; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Maciejowski J; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Kranzusch PJ; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Parker Institute for Cancer Immunotherapy at Dana-Farber Cancer Institute, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Feb 18; Vol. 81 (4), pp. 739-755.e7.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Autoimmune Diseases of the Nervous System/*enzymology
Cytosol/*metabolism
DNA/*metabolism
Exodeoxyribonucleases/*metabolism
Nervous System Malformations/*enzymology
Nucleotidyltransferases/*metabolism
Phosphoproteins/*metabolism
Autoimmune Diseases of the Nervous System/genetics ; Catalysis ; Cell Line, Tumor ; DNA/genetics ; Exodeoxyribonucleases/genetics ; HEK293 Cells ; Humans ; Nervous System Malformations/genetics ; Nucleotidyltransferases/genetics ; Phosphoproteins/genetics
SCR Disease Name :
Aicardi-Goutieres syndrome
Czasopismo naukowe
Tytuł :
ER-directed TREX1 limits cGAS activation at micronuclei.
Autorzy :
Mohr L; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Toufektchan E; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
von Morgen P; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Chu K; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Kapoor A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Maciejowski J; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Feb 18; Vol. 81 (4), pp. 724-738.e9. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Micronuclei, Chromosome-Defective*
Mutation*
Endoplasmic Reticulum/*metabolism
Exodeoxyribonucleases/*metabolism
Nucleotidyltransferases/*metabolism
Phosphoproteins/*metabolism
Endoplasmic Reticulum/genetics ; Enzyme Activation/genetics ; Exodeoxyribonucleases/genetics ; HEK293 Cells ; Humans ; Nucleotidyltransferases/genetics ; Phosphoproteins/genetics ; Protein Transport/genetics
Czasopismo naukowe
Tytuł :
Comparative Study of Interactions between Human cGAS and Inhibitors: Insights from Molecular Dynamics and MM/PBSA Studies.
Autorzy :
Wang X; Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China.; College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.
Li W; Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Enzyme Inhibitors/*chemistry
Nucleotidyltransferases/*chemistry
Amino Acids ; Binding Sites ; Enzyme Inhibitors/pharmacology ; Humans ; Hydrogen Bonding ; Ligands ; Molecular Conformation ; Molecular Structure ; Nucleotidyltransferases/antagonists & inhibitors ; Protein Binding ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Gene Assembly in Agrobacterium via Nucleic Acid Transfer Using Recombinase Technology (GAANTRY).
Autorzy :
Hathwaik LT; United States Department of Agriculture-Agriculture Research Service, Western Regional Research Center, Crop Improvement and Genetics Research Unit, Albany, CA, USA.
Thomson JG; United States Department of Agriculture-Agriculture Research Service, Western Regional Research Center, Crop Improvement and Genetics Research Unit, Albany, CA, USA.
Thilmony R; United States Department of Agriculture-Agriculture Research Service, Western Regional Research Center, Crop Improvement and Genetics Research Unit, Albany, CA, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2238, pp. 3-17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Agrobacterium/*genetics
Crops, Agricultural/*genetics
DNA Nucleotidyltransferases/*metabolism
Genetic Engineering/*methods
Nucleic Acids/*genetics
Plants, Genetically Modified/*genetics
Agrobacterium/pathogenicity ; Crops, Agricultural/microbiology ; DNA Nucleotidyltransferases/genetics ; Genetic Vectors/administration & dosage ; Plants, Genetically Modified/microbiology ; Plasmids/administration & dosage ; Plasmids/genetics ; Recombination, Genetic ; Transgenes/physiology
Czasopismo naukowe
Tytuł :
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Autorzy :
Han F; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, 250012, China.
Guo H; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Wang L; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Zhang Y; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Sun L; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, 250012, China.
Dai C; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, 250012, China.
Wu X; Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2021 Jan; Vol. 202, pp. 108366. Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Immunity, Innate*
Aspergillosis/*genetics
Eye Infections, Fungal/*genetics
Keratitis/*genetics
Membrane Proteins/*genetics
Nucleotidyltransferases/*genetics
Animals ; Aspergillosis/diagnosis ; Aspergillosis/metabolism ; Aspergillus fumigatus/immunology ; Autophagy ; Disease Models, Animal ; Eye Infections, Fungal/diagnosis ; Eye Infections, Fungal/metabolism ; Keratitis/diagnosis ; Keratitis/metabolism ; Male ; Membrane Proteins/biosynthesis ; Mice ; Mice, Inbred C57BL ; Nucleotidyltransferases/biosynthesis ; RNA/genetics ; RNA/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Artificial protein sequences enable recognition of vicinal and distant protein functional relationships.
Autorzy :
Kumar G; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Srinivasan N; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Sandhya S; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
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Źródło :
Proteins [Proteins] 2020 Dec; Vol. 88 (12), pp. 1688-1700. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Protein*
Multigene Family*
Hydrolases/*metabolism
Nucleotidyltransferases/*metabolism
Amino Acid Sequence ; Humans ; Hydrolases/chemistry ; Nucleotidyltransferases/chemistry ; Protein Conformation ; Sequence Homology
Czasopismo naukowe
Tytuł :
A study of Rose Bengal against a 2-keto-3-deoxy-d- manno -octulosonate cytidylyltransferase as an antibiotic candidate.
Autorzy :
Kim S; Graduate School of Pharmaceutical Sciences, Ewha Woman's University, Seoul, Republic of Korea.
Jo S; Graduate School of Pharmaceutical Sciences, Ewha Woman's University, Seoul, Republic of Korea.
Kim MS; Graduate School of Pharmaceutical Sciences, Ewha Woman's University, Seoul, Republic of Korea.
Shin DH; Graduate School of Pharmaceutical Sciences, Ewha Woman's University, Seoul, Republic of Korea.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1414-1421.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Nucleotidyltransferases/*metabolism
Rose Bengal/*pharmacology
Sugar Acids/*chemistry
Enzyme Stability ; Inhibitory Concentration 50 ; Kinetics ; Nucleotidyltransferases/chemistry ; Rosaniline Dyes/chemistry
Czasopismo naukowe
Tytuł :
Keeping innate immune response in check: when cGAS meets the nucleosome.
Autorzy :
Xie W; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA. .
Patel DJ; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA. .
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Źródło :
Cell research [Cell Res] 2020 Dec; Vol. 30 (12), pp. 1055-1056.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Nucleosomes*
Nucleotidyltransferases*/genetics
Immunity, Innate
Czasopismo naukowe

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