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Tytuł:
Inactivation of phosphodiesterase-4B gene in rat nucleus accumbens shell by CRISPR/Cas9 or positive allosteric modulation of the protein affects the motivation to chronically self-administer nicotine.
Autorzy:
Sharp BM; Department of Genetics, Genomics and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA. .
Jiang Q; Department of Genetics, Genomics and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Kim P; Department of Genetics, Genomics and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Chen H; Department of Pharmacology, Addiction Science and Toxicology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 31; Vol. 14 (1), pp. 2562. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Nicotine*
Nucleus Accumbens*/metabolism
Humans ; Rats ; Female ; Animals ; CRISPR-Cas Systems ; Motivation ; Cyclic Nucleotide Phosphodiesterases, Type 4/genetics ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Genome-Wide Association Study ; Rats, Long-Evans ; RNA, Guide, CRISPR-Cas Systems ; Self Administration/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core.
Autorzy:
Knouse MC; Department of Psychology, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA.
Deutschmann AU; Department of Psychology, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA.
Nenov MN; Department of Psychology, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA.
Wimmer ME; Department of Psychology, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA.
Briand LA; Department of Psychology, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA. .; Neuroscience Program, Temple University, Weiss Hall, 1701 North 13th Street, Philadelphia, PA, 19122, USA. .
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Źródło:
Biology of sex differences [Biol Sex Differ] 2023 Aug 18; Vol. 14 (1), pp. 52. Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Glutamic Acid*
Nucleus Accumbens*
Female ; Male ; Mice ; Rats ; Animals ; Rats, Long-Evans ; Sex Characteristics ; Excitatory Postsynaptic Potentials ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clavulanic Acid Improves Memory Dysfunction and Anxiety Behaviors through Upregulating Glutamatergic Transporters in the Nucleus Accumbens of Mice Repeatedly Exposed to Khat Extract.
Autorzy:
Arab AO; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alasmari F; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Albaker AB; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alhazmi HA; Department of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.
Alameen AA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alagail NM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alwaeli SA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Rizwan Ahamad S; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
AlAsmari AF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
AlSharari SD; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 27; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
Catha*
Nucleus Accumbens*/metabolism
Mice ; Rats ; Animals ; Clavulanic Acid/pharmacology ; Anxiety/chemically induced ; Anxiety/drug therapy ; Memory Disorders/metabolism ; Amphetamine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The influence of insight on risky decision making and nucleus accumbens activation.
Autorzy:
Becker M; Department of Psychology, Humboldt University Berlin, 10099, Berlin, Germany. maxi_.
Yu Y; Department of Psychology, Northwestern University, Chicago, IL, 60637, USA. .
Cabeza R; Department of Psychology, Humboldt University Berlin, 10099, Berlin, Germany.; Center for Cognitive Neuroscience, Duke University, Durham, NC, 27708, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 11; Vol. 13 (1), pp. 17159. Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleus Accumbens*
Decision Making*/physiology
Humans ; Brain ; Uncertainty ; Problem Solving ; Dopamine/pharmacology ; Reward ; Risk-Taking
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine.
Autorzy:
Osman A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Seaver Center for Autism Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hofford RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Physiology, Pharmacology and Psychiatry, Wake Forest School of Medicine, 115 S. Chestnut Street, Winston-Salem, NC, 27104, USA.
Meckel KR; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Dave YA; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zeldin SM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shipman AL; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lucerne KE; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Trageser KJ; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Geriatric Research, Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA.
Oguchi T; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Geriatric Research, Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA.
Kiraly DD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; The Seaver Center for Autism Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Department of Physiology, Pharmacology and Psychiatry, Wake Forest School of Medicine, 115 S. Chestnut Street, Winston-Salem, NC, 27104, USA. .; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Department of Psychiatry, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 27; Vol. 13 (1), pp. 12223. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Morphine*
Nucleus Accumbens*/metabolism
Mice ; Male ; Animals ; Polyphenols/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder.
Autorzy:
Matthiesen M; Department of Psychology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.
Khlaifia A; Department of Psychology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.
Steininger CFD Jr; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, M5S3G5, Canada.
Dadabhoy M; Department of Psychology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.
Mumtaz U; Department of Psychology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.
Arruda-Carvalho M; Department of Psychology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada. .; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, M5S3G5, Canada. .
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Źródło:
Molecular brain [Mol Brain] 2023 May 24; Vol. 16 (1), pp. 46. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleus Accumbens*
Autism Spectrum Disorder*
Mice ; Animals ; Mice, Inbred C57BL ; Social Behavior ; Disease Models, Animal ; Sirolimus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Increased iron deposition in nucleus accumbens associated with disease progression and chronicity in migraine.
Autorzy:
Xu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Zhou M; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Wu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Zhao F; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Luo X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Li K; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Zeng Q; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
He J; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Cheng H; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Guan X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Huang P; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China.
Zhang M; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China. .
Liu K; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No 88 Jiefang Road, Hangzhou, Zhejiang, China. .
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Źródło:
BMC medicine [BMC Med] 2023 Apr 07; Vol. 21 (1), pp. 136. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Migraine Disorders*/diagnostic imaging
Nucleus Accumbens*
Humans ; Brain ; Disease Progression ; Iron
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Nucleus Accumbens Tac1 Neural Circuit Regulates Avoidance Responses to Aversive Stimuli.
Autorzy:
He ZX; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Xi K; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Liu KJ; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Yue MH; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Wang Y; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Yin YY; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Liu L; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
He XX; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Yu HL; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Xing ZK; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
Zhu XJ; Key Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Ministry of Education, Changchun 130021, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 22; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Neurons*
Nucleus Accumbens*/physiology
Animals ; Avoidance Learning ; Hypothalamic Area, Lateral ; Motivation ; Neural Pathways/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A thalamic circuit facilitates stress susceptibility via melanocortin 4 receptor-mediated activation of nucleus accumbens shell.
Autorzy:
Deng Q; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.
Zhang SQ; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.
Yang PF; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.
Dong WT; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.
Wang JL; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.
Chen JG; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.; The Research Center for Depression, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China.; Key Laboratory of Neurological Diseases (HUST), Ministry of Education of China, Wuhan City, Hubei, China.; Laboratory of Neuropsychiatric Diseases, The Institute of Brain Research, Huazhong University of Science and Technology, Wuhan, China.
Wang F; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.; The Research Center for Depression, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China.; Key Laboratory of Neurological Diseases (HUST), Ministry of Education of China, Wuhan City, Hubei, China.; Laboratory of Neuropsychiatric Diseases, The Institute of Brain Research, Huazhong University of Science and Technology, Wuhan, China.
Long LH; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei, China.; The Research Center for Depression, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Feb; Vol. 29 (2), pp. 646-658. Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleus Accumbens*/metabolism
Receptor, Melanocortin, Type 4*/genetics
Receptor, Melanocortin, Type 4*/metabolism
Thalamus ; Neurons/metabolism ; Synaptic Transmission
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The HMGB1-RAGE axis in nucleus accumbens facilitates cocaine-induced conditioned place preference via modulating microglial activation.
Autorzy:
Ye J; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gao SQ; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Departments of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
Liu ZC; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen X; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
He JG; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hu ZL; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China.; The Research Center for Depression, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło:
Brain and behavior [Brain Behav] 2024 Mar; Vol. 14 (3), pp. e3457.
Typ publikacji:
Journal Article
MeSH Terms:
HMGB1 Protein*
Cocaine*/pharmacology
Animals ; Rats ; Nucleus Accumbens ; Microglia ; Receptor for Advanced Glycation End Products
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Orexins/Hypocretins: Gatekeepers of Social Interaction and Motivation.
Autorzy:
Ouaidat S; Division of Psychiatry I, Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, Medical University Innsbruck, 6020 Innsbruck, Austria.; Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut P.O. Box 1533, Lebanon.
Amaral IM; Division of Psychiatry I, Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Monteiro DG; Division of Psychiatry I, Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Harati H; Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut P.O. Box 1533, Lebanon.
Hofer A; Division of Psychiatry I, Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, Medical University Innsbruck, 6020 Innsbruck, Austria.
El Rawas R; Division of Psychiatry I, Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, Medical University Innsbruck, 6020 Innsbruck, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neuropeptides*/metabolism
Humans ; Orexins/metabolism ; Motivation ; Social Interaction ; Nucleus Accumbens/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene-environment interactions.
Autorzy:
Nomiya H; Department of Cell Biology and Biochemistry, Division of Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan.
Sakurai K; Laboratory for Advanced Brain Functions, Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Miyamoto Y; Laboratory of Nuclear Transport Dynamics, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka, 567-0085, Japan.
Oka M; Laboratory of Nuclear Transport Dynamics, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka, 567-0085, Japan.
Yoneda Y; The Research Foundation for Microbial Diseases Osaka University, Integrated Life Science Building, Osaka University, 3-1 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Hikida T; Laboratory for Advanced Brain Functions, Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita, Osaka, 565-0871, Japan. .; Department of Research and Drug Discovery, Medical Innovation Center, Kyoto University Graduate School of Medicine, 53 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8397, Japan. .
Yamada M; Department of Cell Biology and Biochemistry, Division of Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan. .; Life Science Innovation Center, University of Fukui, 3-9-1, Bunkyo, Fukui-City, Fukui, 910-8507, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3376. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Schizophrenia*/chemically induced
Schizophrenia*/genetics
Humans ; Mice ; Animals ; Gene-Environment Interaction ; Genome-Wide Association Study ; Psychotropic Drugs/pharmacology ; Phencyclidine/pharmacology ; Nucleus Accumbens/metabolism ; Mammals/metabolism ; alpha Karyopherins/genetics ; alpha Karyopherins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice.
Autorzy:
Madur L; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.; Zurich Neuroscience Center, University of Zurich and ETH Zurich, Zurich, Switzerland.
Ineichen C; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.
Bergamini G; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.
Greter A; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.
Poggi G; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.
Cuomo-Haymour N; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.; Zurich Neuroscience Center, University of Zurich and ETH Zurich, Zurich, Switzerland.
Sigrist H; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland.
Sych Y; Institute of Cellular and Integrative Neuroscience, University of Strasbourg, Strasbourg, France.
Paterna JC; Viral Vector Facility, University of Zurich and ETH Zurich, Zurich, Switzerland.
Bornemann KD; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Viollet C; Global Computational Biology and Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Fernandez-Albert F; Global Computational Biology and Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Alanis-Lobato G; Global Computational Biology and Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Hengerer B; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Pryce CR; Preclinical Laboratory, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich (PUK) and University of Zurich (UZH), Zurich, Switzerland. .; Zurich Neuroscience Center, University of Zurich and ETH Zurich, Zurich, Switzerland. .
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Źródło:
Communications biology [Commun Biol] 2023 Apr 15; Vol. 6 (1), pp. 422. Date of Electronic Publication: 2023 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleus Accumbens*
Basolateral Nuclear Complex*
Mice ; Male ; Animals ; Amygdala/physiology ; Neurons/physiology ; Reward
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A single-nucleus transcriptomics study of alcohol use disorder in the nucleus accumbens.
Autorzy:
van den Oord EJCG; Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Xie LY; Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Zhao M; Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Aberg KA; Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Clark SL; Department of Psychiatry & Behavioral Sciences, Texas A&M University, College Station, Texas, USA.
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Źródło:
Addiction biology [Addict Biol] 2023 Jan; Vol. 28 (1), pp. e13250.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Nucleus Accumbens*/metabolism
Alcoholism*/genetics
Alcoholism*/metabolism
Male ; Female ; Animals ; Mice ; Transcriptome ; Receptors, Dopamine D1/metabolism ; Alcohol Drinking ; Receptors, Dopamine D2/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effective connectivity of the amygdala during the consumption of erotic, sexual humor, and monetary rewards with a DCM-PEB approach.
Autorzy:
Chan YC; Department of Educational Psychology and Counseling, National Tsing Hua University, Hsinchu, Taiwan.
Chou TL; Department of Psychology, National Taiwan University, Taipei, Taiwan.
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Źródło:
PloS one [PLoS One] 2022 Dec 29; Vol. 17 (12), pp. e0279281. Date of Electronic Publication: 2022 Dec 29 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amygdala*/physiology
Nucleus Accumbens*/diagnostic imaging
Nucleus Accumbens*/physiology
Bayes Theorem ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/physiology ; Reward ; Magnetic Resonance Imaging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors.
Autorzy:
Serra MP; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Sanna F; Department of Life and Environmental Sciences, Section of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Boi M; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Poddighe L; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Secci L; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Trucas M; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Fernández-Teruel A; Medical Psychology Unit, Department of Psychiatry and Forensic Medicine & Institute of Neurosciences, School of Medicine, Autonomous University of Barcelona, Bellaterra, 08193 Barcelona, Spain.
Corda MG; Department of Life and Environmental Sciences, Section of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Giorgi O; Department of Life and Environmental Sciences, Section of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Quartu M; Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 30; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Nucleus Accumbens*/metabolism
Rats ; Animals ; Ventral Tegmental Area/metabolism ; Prefrontal Cortex/metabolism ; Cerebral Cortex/metabolism ; Receptor, trkB/genetics ; Receptor, trkB/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sucrose drinking mimics effects of nucleus accumbens µ-opioid receptor stimulation on fat intake and brain c-Fos-expression.
Autorzy:
Koekkoek LL; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Masís-Vargas A; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Kool T; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Eggels L; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
van der Gun LL; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Lamuadni K; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Slomp M; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Diepenbroek C; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Kalsbeek A; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
la Fleur SE; Laboratory of Endocrinology, Department of Clinical Chemistry, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Location AMC, University of Amsterdam, Neuroscience Amsterdam, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam, The Netherlands.; Metabolism and Reward Group, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2022 Nov; Vol. 25 (11), pp. 2408-2420. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Nucleus Accumbens*/metabolism
Receptors, Opioid*/metabolism
Animals ; Rats ; Brain/metabolism ; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-/pharmacology ; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-/metabolism ; Rats, Sprague-Dawley ; Receptors, Opioid, mu/agonists ; Receptors, Opioid, mu/metabolism ; Sucrose ; Water ; Proto-Oncogene Proteins c-fos
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The nucleus accumbens dopamine increase, typically triggered by sexual stimuli in male rats, is no longer produced when animals are sexually inhibited due to sexual satiety.
Autorzy:
Canseco-Alba A; Dirección de Investigación, Instituto Nacional de Neurología y Neurocirugía 'Manuel Velasco Suárez, ' Av. Insurgentes Sur 3877, Col. La Fama, 14269, Mexico City, Mexico. .
Coffeen U; Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramon de La Fuente Muñiz, Mexico City, Mexico.
Jaimes O; Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramon de La Fuente Muñiz, Mexico City, Mexico.
Pellicer F; Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramon de La Fuente Muñiz, Mexico City, Mexico.
Rodríguez-Manzo G; Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados (Cinvestav-Sede Sur), Calzada de los Tenorios 235, Col. Granjas Coapa, 14330, Mexico City, Mexico. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Nov; Vol. 239 (11), pp. 3679-3695. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
Nucleus Accumbens*/metabolism
Dopamine*/metabolism
Rats ; Male ; Female ; Animals ; Sexual Behavior, Animal/physiology ; Endocannabinoids/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Patterns of ethanol intake in male rats with partial dopamine transporter deficiency.
Autorzy:
Kuiper LB; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Roberts JB; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Estave PM; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Leo D; Department of Neurosciences, University of Mons, Mons, Belgium.
Gainetdinov RR; Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia.; St. Petersburg University Hospital, St. Petersburg State University, St. Petersburg, Russia.
Jones SR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
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Źródło:
Genes, brain, and behavior [Genes Brain Behav] 2023 Dec; Vol. 22 (6), pp. e12847. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Ethanol*
Dopamine Plasma Membrane Transport Proteins*/genetics
Humans ; Rats ; Male ; Animals ; Dopamine ; Rats, Wistar ; Alcohol Drinking/genetics ; Nucleus Accumbens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 29701

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