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Wyszukujesz frazę ""O'Byrne, K. J."" wg kryterium: Autor


Tytuł :
Surgical resection for non-small cell lung cancer: clinical features and outcomes for a consecutive series at an Irish tertiary referral centre.
Autorzy :
Al-Alao BS; Thoracic Oncology Research Group, St. James's Hospital, Dublin 8, Ireland. />O'Callaghan DS
Gately K
Nicholson S
Coate LE
O'Connell F
McGovern E
O'Byrne KJ
Young VK
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Źródło :
Irish journal of medical science [Ir J Med Sci] 2013 Jun; Vol. 182 (2), pp. 217-25. Date of Electronic Publication: 2012 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*surgery
Lung Neoplasms/*surgery
Age Factors ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Female ; Humans ; Ireland/epidemiology ; Kaplan-Meier Estimate ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Pneumonectomy ; Prognosis ; Referral and Consultation ; Sex Factors ; Smoking/adverse effects ; Survival Rate ; Thoracic Surgical Procedures
Czasopismo naukowe
Tytuł :
Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.
Autorzy :
Paul I; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Northern Ireland, UK.
Chacko AD
Stasik I
Busacca S
Crawford N
McCoy F
McTavish N
Wilson B
Barr M
O'Byrne KJ
Longley DB
Fennell DA
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Źródło :
Cell death & disease [Cell Death Dis] 2012 Dec 20; Vol. 3, pp. e449. Date of Electronic Publication: 2012 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Carcinoma, Non-Small-Cell Lung/*enzymology
Caspase 8/*metabolism
Gene Expression Regulation, Enzymologic/*drug effects
Lung Neoplasms/*enzymology
Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/physiopathology ; Caspase 8/genetics ; Cell Line, Tumor ; Cisplatin ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Lung Neoplasms/physiopathology ; Protein Processing, Post-Translational/drug effects
Czasopismo naukowe
Tytuł :
Prognostic factors in patients with advanced non-small cell lung cancer: data from the phase III FLEX study.
Autorzy :
Pirker R; Department of Medicine I, Medical University Vienna, Vienna, Austria. />Pereira JR
Szczesna A
von Pawel J
Krzakowski M
Ramlau R
Vynnychenko I
Park K
Eberhardt WE
de Marinis F
Heeger S
Goddemeier T
O'Byrne KJ
Gatzemeier U
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2012 Aug; Vol. 77 (2), pp. 376-82. Date of Electronic Publication: 2012 Apr 11.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*drug therapy
Lung Neoplasms/*pathology
Aged ; Aged, 80 and over ; Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Carcinoma, Non-Small-Cell Lung/mortality ; Cetuximab ; Female ; Humans ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration.
Autorzy :
Field JK; Roy Castle Lung Cancer Research Programme, Cancer Research Centre, University of Liverpool, 200 London Road, Liverpool, L3 9TA, UK. J.K. />Liloglou T
Niaz A
Bryan J
Gosney JR
Giles T
Brambilla C
Brambilla E
Vesin A
Timsit JF
Hainaut P
Martinet Y
Vignaud JM
Thunnissen FB
Prinsen C
Snijders PJ
Smit EF
Sozzi G
Roz L
Risch A
Becker HD
Elborn JS
Magee ND
Montuenga LM
Pajares MJ
Lozano MD
O'Byrne KJ
Harrison DJ
Niklinski J
Cassidy A
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Corporate Authors :
EUELC Collaborators
Źródło :
The European respiratory journal [Eur Respir J] 2009 Dec; Vol. 34 (6), pp. 1477-86.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*diagnosis
Lung Neoplasms/*diagnosis
Aged ; Carcinoma, Non-Small-Cell Lung/metabolism ; DNA Methylation ; DNA Mutational Analysis ; Epithelium/metabolism ; Europe ; Female ; Humans ; Immunohistochemistry/methods ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Oligonucleotide Array Sequence Analysis ; Receptors, Retinoic Acid/metabolism ; Telomerase/metabolism
Czasopismo naukowe
Tytuł :
Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer.
Autorzy :
Rosell R; Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain. />Robinet G
Szczesna A
Ramlau R
Constenla M
Mennecier BC
Pfeifer W
O'Byrne KJ
Welte T
Kolb R
Pirker R
Chemaissani A
Perol M
Ranson MR
Ellis PA
Pilz K
Reck M
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2008 Feb; Vol. 19 (2), pp. 362-9. Date of Electronic Publication: 2007 Oct 17.
Typ publikacji :
Clinical Trial, Phase II; Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Carcinoma, Non-Small-Cell Lung/*drug therapy
Carcinoma, Non-Small-Cell Lung/*mortality
Lung Neoplasms/*drug therapy
Lung Neoplasms/*mortality
Neoplasm Invasiveness/*pathology
Adult ; Aged ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal, Humanized ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Carcinoma, Non-Small-Cell Lung/pathology ; Cetuximab ; Cisplatin/administration & dosage ; Cisplatin/adverse effects ; Confidence Intervals ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/pathology ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasm Staging ; Probability ; Reference Values ; Risk Assessment ; Survival Analysis ; Treatment Outcome ; Vinblastine/administration & dosage ; Vinblastine/adverse effects ; Vinblastine/analogs & derivatives ; Vinorelbine
Czasopismo naukowe
Tytuł :
Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer.
Autorzy :
Richardson CM; Department of Respiratory Medicine, Queens Medical Centre, Nottingham NG72UH, UK.
Richardson D
Swinson DE
Swain WA
Cox G
O'Byrne KJ
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2005 Apr; Vol. 48 (1), pp. 47-57.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Biomarkers, Tumor/*analysis
Carcinoma, Non-Small-Cell Lung/*genetics
ErbB Receptors/*biosynthesis
Lung Neoplasms/*genetics
Prostaglandin-Endoperoxide Synthases/*biosynthesis
Aged ; Blotting, Western ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/surgery ; Cyclooxygenase 2 ; Cytoplasm ; ErbB Receptors/analysis ; ErbB Receptors/genetics ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Membrane Proteins ; Prognosis ; Prostaglandin-Endoperoxide Synthases/analysis ; Prostaglandin-Endoperoxide Synthases/genetics ; Survival Analysis ; Tumor Cells, Cultured ; Up-Regulation
Czasopismo naukowe
Tytuł :
Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancer.
Autorzy :
Swinson DE; Cancer Centre, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK. />Cox G
O'Byrne KJ
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Źródło :
British journal of cancer [Br J Cancer] 2004 Oct 04; Vol. 91 (7), pp. 1301-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Models, Theoretical*
Antigens, Neoplasm/*biosynthesis
Biomarkers, Tumor/*biosynthesis
Carbonic Anhydrases/*biosynthesis
Carcinoma, Non-Small-Cell Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*pathology
ErbB Receptors/*biosynthesis
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Adult ; Aged ; Antigens, Neoplasm/analysis ; Carbonic Anhydrase IX ; Female ; Gene Expression Profiling ; Humans ; Immunohistochemistry ; Male ; Matrix Metalloproteinase 9/biosynthesis ; Middle Aged ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Endothelin-1 is a novel prognostic factor in non-small cell lung cancer.
Autorzy :
Arun C; Department of Surgery , University Hospitals of Leicester NHS Trust, United Kingdom. />DeCatris M
Hemingway DM
London NJ
O'Byrne KJ
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Źródło :
The International journal of biological markers [Int J Biol Markers] 2004 Oct-Dec; Vol. 19 (4), pp. 262-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Carcinoma, Non-Small-Cell Lung/*metabolism
Endothelin-1/*biosynthesis
Endothelin-1/*blood
Lung Neoplasms/*metabolism
Carcinoma, Non-Small-Cell Lung/blood ; Cell Line, Tumor ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Lung Neoplasms/blood ; Male ; Neovascularization, Pathologic ; Prognosis ; RNA, Messenger/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer.
Autorzy :
Cox G; Department of Medical Oncology, Leicester Royal Infirmary, Welford Road, Leicester LE1 5WW, UK
Louise Jones J
Andi A
Abrams KR
O'Byrne KJ
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2001 Dec; Vol. 34 (3), pp. 417-26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*pathology
Proto-Oncogene Proteins c-bcl-2/*metabolism
Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/surgery ; Chi-Square Distribution ; ErbB Receptors/metabolism ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/metabolism ; Lung Neoplasms/surgery ; Male ; Matrix Metalloproteinases/metabolism ; Middle Aged ; Neoplasm Staging/methods ; Neovascularization, Pathologic ; Predictive Value of Tests ; Prognosis ; Proportional Hazards Models ; Retrospective Studies
Czasopismo naukowe
Tytuł :
A biological staging model for operable non-small cell lung cancer.
Autorzy :
Cox G; Department of Medical Oncology, Leicester Royal Infirmary, Leicester LE1 5WW, UK.
Jones JL
Andi A
Waller DA
O'Byrne KJ
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Źródło :
Thorax [Thorax] 2001 Jul; Vol. 56 (7), pp. 561-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Non-Small-Cell Lung/*diagnosis
ErbB Receptors/*metabolism
Lung Neoplasms/*diagnosis
Matrix Metalloproteinases/*metabolism
Neovascularization, Pathologic/*diagnosis
Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/blood supply ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/blood supply ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging/methods ; Prognosis ; Regression Analysis ; Retrospective Studies ; Survival Analysis
Czasopismo naukowe
Tytuł :
Herceptest: HER2 expression and gene amplification in non-small cell lung cancer.
Autorzy :
Cox G; Department of Medical Oncology, Leicester Royal Infirmary, Leicester, United Kingdom.
Vyberg M
Melgaard B
Askaa J
Oster A
O'Byrne KJ
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Źródło :
International journal of cancer [Int J Cancer] 2001 May 15; Vol. 92 (4), pp. 480-3.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*metabolism
Lung Neoplasms/*metabolism
Receptor, ErbB-2/*biosynthesis
Adenocarcinoma/metabolism ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal, Humanized ; Carcinoma, Large Cell/metabolism ; Cell Membrane/metabolism ; Female ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Neoplasms, Squamous Cell/metabolism ; Ploidies ; Retrospective Studies ; Trastuzumab
Czasopismo naukowe
Tytuł :
Gemcitabine and paclitaxel associated pneumonitis in non-small cell lung cancer: report of a phase I/II dose-escalating study.
Autorzy :
Thomas AL; Department of Oncology, Leicester Royal Infirmary, UK.
Cox G
Sharma RA
Steward WP
Shields F
Jeyapalan K
Muller S
O'Byrne KJ
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2000 Dec; Vol. 36 (18), pp. 2329-34.
Typ publikacji :
Clinical Trial; Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Carcinoma, Non-Small-Cell Lung/*drug therapy
Deoxycytidine/*adverse effects
Lung Neoplasms/*drug therapy
Paclitaxel/*adverse effects
Pneumonia/*chemically induced
Aged ; Cohort Studies ; Deoxycytidine/administration & dosage ; Deoxycytidine/analogs & derivatives ; Dose-Response Relationship, Drug ; Female ; Humans ; Male ; Maximum Allowable Concentration ; Middle Aged ; Paclitaxel/administration & dosage
Czasopismo naukowe
Tytuł :
Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer.
Autorzy :
Cox G; Department of Medical Oncology, Leicester Royal Infirmary, Welford Road, LE1 5WW, Leicester, UK.
Walker RA
Andi A
Steward WP
O'Byrne KJ
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2000 Sep; Vol. 29 (3), pp. 169-77.
Typ publikacji :
Journal Article
MeSH Terms :
Neovascularization, Pathologic*
Platelet Activation*
Carcinoma, Non-Small-Cell Lung/*blood supply
Lung Neoplasms/*blood supply
Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/surgery ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Platelet Count ; Pregnancy ; Prognosis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer.
Autorzy :
O'Byrne KJ; University Department of Oncology, Leicester Royal Infirmary, UK.
Koukourakis MI
Giatromanolaki A
Cox G
Turley H
Steward WP
Gatter K
Harris AL
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Źródło :
British journal of cancer [Br J Cancer] 2000 Apr; Vol. 82 (8), pp. 1427-32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*blood supply
Carcinoma, Non-Small-Cell Lung/*pathology
Endothelial Growth Factors/*analysis
Lung Neoplasms/*pathology
Lymphokines/*analysis
Neovascularization, Pathologic/*pathology
Thymidine Phosphorylase/*analysis
Adenocarcinoma/blood supply ; Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Analysis of Variance ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/surgery ; Carcinoma, Squamous Cell/blood supply ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Humans ; Immunohistochemistry ; Lung Neoplasms/blood supply ; Lung Neoplasms/enzymology ; Lung Neoplasms/mortality ; Lung Neoplasms/surgery ; Microcirculation/pathology ; Neoplasm Staging ; Observer Variation ; Prognosis ; Protein Isoforms/analysis ; Survival Analysis ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
Czasopismo naukowe
Tytuł :
Angiogenesis and non-small cell lung cancer.
Autorzy :
Cox G; University Department of Medical Oncology, Leicester Royal Infirmary, UK.
Jones JL
Walker RA
Steward WP
O'Byrne KJ
Pokaż więcej
Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2000 Feb; Vol. 27 (2), pp. 81-100.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neovascularization, Pathologic*
Carcinoma, Non-Small-Cell Lung/*blood supply
Lung Neoplasms/*blood supply
Angiogenesis Inhibitors/pharmacology ; Apoptosis ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/pathology ; Growth Substances/pharmacology ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Matrix Metalloproteinases/metabolism
Czasopismo naukowe
Tytuł :
Does immunointensity account for the differences in prognostic significance of Bcl-2 expression in non-small cell lung cancer?
Autorzy :
Cox G; Glenfield Hospital, Department of Respiratory Medicine, Leicester, UK.
Walker RA
Muller S
Abrams KR
Steward WP
O'Byrne KJ
Pokaż więcej
Źródło :
Pathology oncology research : POR [Pathol Oncol Res] 2000; Vol. 6 (2), pp. 87-92.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*mortality
Lung Neoplasms/*mortality
Proto-Oncogene Proteins c-bcl-2/*metabolism
Adult ; Age Factors ; Aged ; Carcinoma, Non-Small-Cell Lung/metabolism ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Sex Factors ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
The plasmin cascade and matrix metalloproteinases in non-small cell lung cancer.
Autorzy :
Cox G; University Department of Medical Oncology, Leicester Royal Infirmary, UK.
Steward WP
O'Byrne KJ
Pokaż więcej
Źródło :
Thorax [Thorax] 1999 Feb; Vol. 54 (2), pp. 169-79.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*metabolism
Growth Substances/*metabolism
Lung Neoplasms/*metabolism
Metalloendopeptidases/*metabolism
Apoptosis/physiology ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Enzyme Inhibitors/therapeutic use ; Fibrinolysin/metabolism ; Humans ; Lung Neoplasms/drug therapy ; Metalloendopeptidases/antagonists & inhibitors ; Prognosis
Czasopismo naukowe

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