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Wyświetlanie 1-20 z 63423
Tytuł:
FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression.
Autorzy:
Wang J; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Wang C; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Hu A; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Yu K; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Kuang Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Gajendran B; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; School of Pharmaceutical Sciences, Guizhou Medical University, Guizhou Province, Guiyang, 550025, People's Republic of China.
Zacksenhaus E; Department of Medicine, University of Toronto, Toronto, ON, Canada.; Division of Advanced Diagnostics, Toronto General Research Institute, University Health Network, Toronto, ON, Canada.
Sample KM; eBond Pharmaceutical Technology Ltd, Chengdu, Sichuan, People's Republic of China.
Xiao X; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China.; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China.
Liu W; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China. .; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China. .
Ben-David Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang-550014, Guizhou, People's Republic of China. .; Natural Products Research Center of Guizhou Province, High Tech Zone, Province Science City, Baiyun District, Guiyang, 550014, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Mar 09; Vol. 24 (1), pp. 326. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Erythroblastic, Acute*/genetics
Leukemia, Erythroblastic, Acute*/metabolism
Proto-Oncogene Protein c-fli-1*/genetics
Proto-Oncogene Protein c-fli-1*/metabolism
Humans ; Adaptor Proteins, Signal Transducing/metabolism ; Cell Line, Tumor ; Gene Expression Regulation ; Gene Expression Regulation, Neoplastic ; Genes, Tumor Suppressor ; Oncogene Proteins, Fusion/genetics ; RNA, Small Interfering/genetics ; RNA-Binding Protein EWS/genetics ; Protein Tyrosine Phosphatases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Concurrent KRAS p.G12C mutation and ANK3::RET fusion in a patient with metastatic colorectal cancer: a case report.
Autorzy:
Bedau T; Department of Pathology, University Hospital Cologne, Cologne, Germany. .
Heydt C; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Siebolts U; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Zander T; Department I of Internal Medicine, Center for Integrated Oncology (CIO), University of Cologne, Cologne, Germany.
Kraemer M; Department I of Internal Medicine, Center for Integrated Oncology (CIO), University of Cologne, Cologne, Germany.
Loeser H; Institut für Pathologie Köln-Deutz, Cologne, Germany.
Buettner R; Department of Pathology, University Hospital Cologne, Cologne, Germany.
Quaas A; Department of Pathology, University Hospital Cologne, Cologne, Germany.
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Źródło:
Diagnostic pathology [Diagn Pathol] 2024 Mar 27; Vol. 19 (1), pp. 55. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Proto-Oncogene Proteins p21(ras)*/genetics
Colonic Neoplasms*
Female ; Humans ; Aged, 80 and over ; Carcinogenesis ; Cell Transformation, Neoplastic ; Mutation ; Proto-Oncogene Proteins c-ret ; Ankyrins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells.
Autorzy:
Shan F; Medical Research Centre, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Zhang N; Department of Respiratory and Critical Care, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Yao X; Medical Research Centre, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Li Y; Department of Neurology, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining City, Shandong Province, 272029, China.
Wang Z; Cheeloo Medical College, Shandong University, Jinan, Shandong Province, China.
Zhang C; College of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Wang Y; Medical Research Centre, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China. wangyuzhong_.; Department of Neurology, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining City, Shandong Province, 272029, China. wangyuzhong_.
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 01; Vol. 22 (1), pp. 93. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Proto-Oncogene Proteins c-akt*/metabolism
Mice ; Animals ; Phosphatidylinositol 3-Kinases/metabolism ; Up-Regulation ; Proteomics ; Proto-Oncogene Proteins c-myc/metabolism ; Glycolysis ; Schwann Cells/metabolism ; Phosphatidylinositol 3-Kinase/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Oxidative Stress ; Mammals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Autorzy:
Tamura S; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Tazawa H; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.; Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan.
Hori N; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Li Y; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Yamada M; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Kikuchi S; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Kuroda S; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Urata Y; Oncolys BioPharma, Inc., Tokyo, Japan.
Kagawa S; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Fujiwara T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
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Źródło:
PloS one [PLoS One] 2023 Nov 16; Vol. 18 (11), pp. e0294491. Date of Electronic Publication: 2023 Nov 16 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Proto-Oncogene Proteins B-raf*/metabolism
Colorectal Neoplasms*/therapy
Colorectal Neoplasms*/drug therapy
Humans ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Adenoviridae/genetics ; Adenoviridae/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Caco-2 Cells ; Cell Line, Tumor ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Apoptosis/genetics ; TOR Serine-Threonine Kinases/metabolism ; Autophagy/genetics ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism.
Autorzy:
Zhang J; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
Liu YP; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
Bu LJ; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
Liu Q; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
Pei CX; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
Huo WJ; College of Animal Sciences, Shanxi Agricultural University, Taigu, Shanxi, P. R. China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (8), pp. 3796-3807. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Mammary Glands, Animal*/metabolism
Female ; Cattle ; Animals ; Proliferating Cell Nuclear Antigen/metabolism ; Proliferating Cell Nuclear Antigen/pharmacology ; TOR Serine-Threonine Kinases/genetics ; Diet/veterinary ; Milk/metabolism ; Epithelial Cells/metabolism ; RNA, Messenger/genetics ; Lactation/genetics ; Dietary Supplements ; Folic Acid/pharmacology ; Folic Acid/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeting CRAF kinase in anti-cancer therapy: progress and opportunities.
Autorzy:
Wang P; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, 450052, Henan, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450000, China.
Laster K; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450000, China.
Jia X; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, 450052, Henan, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450000, China.
Dong Z; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China. .; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, 450052, Henan, China. .; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450000, China. .; Department of Pathophysiology, School of Basic Medical Sciences, China-US (Henan) Hormel Cancer Institute, AMS, College of Medicine, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450001, Henan, China. .
Liu K; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China. .; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, 450052, Henan, China. .; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450000, China. .; Department of Pathophysiology, School of Basic Medical Sciences, China-US (Henan) Hormel Cancer Institute, AMS, College of Medicine, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450001, Henan, China. .; Basic Medicine Sciences Research Center, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450052, Henan, China. .; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou, 450000, Henan, China. .; Provincial Cooperative Innovation Center for Cancer Chemoprevention, Zhengzhou University, Zhengzhou, 450000, Henan, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Dec 18; Vol. 22 (1), pp. 208. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins B-raf*
MAP Kinase Signaling System*
Humans ; Cell Line, Tumor ; Signal Transduction ; Phosphorylation ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-raf/genetics ; Proto-Oncogene Proteins c-raf/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.
Autorzy:
Xie B; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tang W; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wen S; Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chen F; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yang C; Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wang M; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Liang W; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Dec 27; Vol. 14 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Growth Differentiation Factor 15*/pharmacology
Platelet Aggregation*/genetics
Proto-Oncogene Proteins c-ret*
Glial Cell Line-Derived Neurotrophic Factor Receptors*/metabolism
Humans ; Adenosine Diphosphate/pharmacology ; ErbB Receptors ; Extracellular Signal-Regulated MAP Kinases ; Proto-Oncogene Proteins c-akt ; Transforming Growth Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cyasterone has a protective effect on steroid-induced Osteonecrosis of the femoral head.
Autorzy:
Sun Y; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Liang M; Department of Obstetrics, Guangdong Women and Chifldren Hospital, Guangzhou, 510010, Guangdong Province, China.
Xing Y; The First Clinical College of Guangzhouf University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Duan Y; The First Clinical College of Guangzhouf University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Zhang S; Department of Sports Medicine, Heyuan Hospital of Chinese Medicine, Heyuan, 517000, Guangdong Province, China.
Deng B; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Xiang X; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Zhou B; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
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Źródło:
PloS one [PLoS One] 2023 Oct 30; Vol. 18 (10), pp. e0293530. Date of Electronic Publication: 2023 Oct 30 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Osteonecrosis*/chemically induced
Osteonecrosis*/drug therapy
Osteonecrosis*/prevention & control
Rats ; Animals ; bcl-2-Associated X Protein/metabolism ; Femur Head/pathology ; Cytochromes c/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Suppressor Protein p53/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Steroids/metabolism ; Apoptosis ; Dexamethasone/adverse effects ; Dexamethasone/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preliminary exploration of the effects of environmental factors on the microsatellite status of BRAF-mutated colorectal cancer.
Autorzy:
Tian B; Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Chen G; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Shi X; Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Jiang L; Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Jiang T; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Li Q; Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China.
Yuan L; Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China. yuanlin_.
Qin J; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China. .
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Źródło:
World journal of surgical oncology [World J Surg Oncol] 2023 Aug 25; Vol. 21 (1), pp. 264. Date of Electronic Publication: 2023 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Colorectal Neoplasms*/genetics
Humans ; Proto-Oncogene Proteins p21(ras)/genetics ; Mutation ; Microsatellite Repeats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optogenetic dissection of RET signaling reveals robust activation of ERK and enhanced filopodia-like protrusions of regenerating axons.
Autorzy:
Hyeon B; Department of Life Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-Ro, Yuseong-Gu, Daejeon, 305-701, Republic of Korea.
Lee H; Department of Life Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-Ro, Yuseong-Gu, Daejeon, 305-701, Republic of Korea.
Kim N; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Heo WD; Department of Life Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-Ro, Yuseong-Gu, Daejeon, 305-701, Republic of Korea. .; Korea Advanced Institute of Science and Technology (KAIST), KAIST Institute for the BioCentury, 291 Daehak-Ro, Yuseong-Gu, Daejeon, 305-701, Republic of Korea. .
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Źródło:
Molecular brain [Mol Brain] 2023 Jul 04; Vol. 16 (1), pp. 56. Date of Electronic Publication: 2023 Jul 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*
Optogenetics*
Mice ; Animals ; Humans ; Pseudopodia/metabolism ; Proto-Oncogene Proteins c-ret/genetics ; Proto-Oncogene Proteins c-ret/metabolism ; Axons/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
STS-1 and STS-2, Multi-Enzyme Proteins Equipped to Mediate Protein-Protein Interactions.
Autorzy:
Hayes B; Department of Chemistry and Biochemistry, San Diego State University, 5500 Campanile Dr., San Diego, CA 92105, USA.
van der Geer P; Department of Chemistry and Biochemistry, San Diego State University, 5500 Campanile Dr., San Diego, CA 92105, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 24; Vol. 24 (11). Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proto-Oncogene Proteins*/metabolism
Signal Transduction*
Amino Acid Sequence ; Protein-Tyrosine Kinases/metabolism ; Tyrosine/metabolism ; src Homology Domains ; Proto-Oncogene Proteins c-cbl/metabolism ; Phosphorylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging.
Autorzy:
Karakaslar EO; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Katiyar N; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Hasham M; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, Maine, USA.
Youn A; Sanofi, Bridgewater, New Jersey, USA.
Sharma S; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Chung CH; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Marches R; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Korstanje R; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, Maine, USA.
Banchereau J; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Immunai, New York, New York, USA.
Ucar D; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Apr; Vol. 22 (4), pp. e13792. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-fos*/genetics
Proto-Oncogene Proteins c-fos*/metabolism
Transcription Factor AP-1*/genetics
Transcription Factor AP-1*/metabolism
Animals ; Humans ; Mice ; Aging/genetics ; Interleukin-6/metabolism ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-jun/genetics ; Proto-Oncogene Proteins c-jun/metabolism ; Transcriptional Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An immunohistochemical study of double-expressor lymphomas and its correlation with cell of origin.
Autorzy:
Ananthamurthy A; Department of Pathology, St John's Medical College, Bengaluru, Karnataka, India.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Apr; Vol. 19 (Supplement), pp. S0.
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-myc*
Lymphoma, Large B-Cell, Diffuse*/pathology
Humans ; Proto-Oncogene Proteins c-bcl-6/genetics ; Proto-Oncogene Proteins c-bcl-2/genetics ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification and characterization of novel ETV4 splice variants in prostate cancer.
Autorzy:
Cosi I; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.; ICCOM - National Research Council, Sesto Fiorentino, Florence, Italy.
Moccia A; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.
Pescucci C; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.
Munagala U; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.
Di Giorgio S; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.
Sineo I; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.
Conticello SG; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.; IFC - National Research Council, Pisa, Italy.
Notaro R; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy.; IFC - National Research Council, Pisa, Italy.
De Angioletti M; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Viale Pieraccini 6, 50139, Florence, Italy. .; ICCOM - National Research Council, Sesto Fiorentino, Florence, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 31; Vol. 13 (1), pp. 5267. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prostatic Neoplasms*/pathology
Proto-Oncogene Proteins c-ets*/genetics
Proto-Oncogene Proteins c-ets*/metabolism
Humans ; Male ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Proto-Oncogene Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek's Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses.
Autorzy:
Teng M; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs of China and Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Liu JL; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs of China and Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.
Luo Q; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs of China and Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Zheng LP; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs of China and Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.
Yao Y; The Pirbright Institute & UK-China Centre of Excellence for Research on Avian Diseases, Pirbright, Ash Road, Guildford GU24 0NF, UK.
Nair V; The Pirbright Institute & UK-China Centre of Excellence for Research on Avian Diseases, Pirbright, Ash Road, Guildford GU24 0NF, UK.
Zhang GP; International Joint Research Center of National Animal Immunology and College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou University, Yangzhou 225009, China.
Luo J; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs of China and Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
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Źródło:
Viruses [Viruses] 2023 Mar 23; Vol. 15 (4). Date of Electronic Publication: 2023 Mar 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Marek Disease*
Herpesvirus 2, Gallid*/genetics
Poultry Diseases*
Oncogene Proteins, Viral*/genetics
Animals ; Gene Editing ; CRISPR-Cas Systems ; Antibodies, Monoclonal/metabolism ; Oncogene Proteins/metabolism ; Chickens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced Apoptosis and Loss of Cell Viability in Melanoma Cells by Combined Inhibition of ERK and Mcl-1 Is Related to Loss of Mitochondrial Membrane Potential, Caspase Activation and Upregulation of Proapoptotic Bcl-2 Proteins.
Autorzy:
Peng Z; Skin Cancer Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.; Clinical Medicine, University of South China, Hengyang 421001, China.
Gillissen B; Department of Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13125 Berlin, Germany.
Richter A; Department of Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13125 Berlin, Germany.
Sinnberg T; Skin Cancer Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.; Division of Dermatooncology, Department of Dermatology, University Tübingen, 72076 Tübingen, Germany.
Schlaak MS; Skin Cancer Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Eberle J; Skin Cancer Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 04; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Melanoma*/metabolism
Humans ; Vemurafenib/pharmacology ; Up-Regulation ; Cell Survival ; Membrane Potential, Mitochondrial ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Protein Kinase Inhibitors/pharmacology ; Caspases/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FLI1 regulates radiotherapy resistance in nasopharyngeal carcinoma through TIE1-mediated PI3K/AKT signaling pathway.
Autorzy:
Chen E; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Huang J; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Chen M; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Wu J; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Ouyang P; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Wang X; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Shi D; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Liu Z; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Zhu W; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Sun H; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Yang S; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Zhang B; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Deng W; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China. .
Qiu H; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China. .
Xie F; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Feb 22; Vol. 21 (1), pp. 134. Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nasopharyngeal Carcinoma*/genetics
Nasopharyngeal Carcinoma*/radiotherapy
Nasopharyngeal Neoplasms*/genetics
Nasopharyngeal Neoplasms*/radiotherapy
Proto-Oncogene Protein c-fli-1*/genetics
Radiation Tolerance*/genetics
Receptor, TIE-1*/genetics
Humans ; Cell Line, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disulfiram/Cu Kills and Sensitizes BRAF -Mutant Thyroid Cancer Cells to BRAF Kinase Inhibitor by ROS-Dependently Relieving Feedback Activation of MAPK/ERK and PI3K/AKT Pathways.
Autorzy:
Xie J; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Liu J; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Zhao M; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Li X; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Wang Y; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Zhao Y; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Cao H; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Ji M; Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Chen M; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Hou P; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 08; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Thyroid Neoplasms*/pathology
Humans ; Vemurafenib/therapeutic use ; Proto-Oncogene Proteins c-akt/metabolism ; Disulfiram/therapeutic use ; Phosphatidylinositol 3-Kinases/metabolism ; Reactive Oxygen Species ; Sulfonamides/pharmacology ; Indoles/pharmacology ; Feedback ; Protein Kinase Inhibitors/pharmacology ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of MDM2 Overexpression in Ameloblastomas with MDM2 Amplification and BRAF Expression.
Autorzy:
Tosios KI; Department of Oral Pathology & Medicine and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Kalogirou EM; Faculty of Health and Rehabilitation Sciences, Metropolitan College, 15125 Athens, Greece.
Koutlas IG; Division of Oral Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Ameloblastoma*/genetics
Ameloblastoma*/metabolism
Proto-Oncogene Proteins B-raf*/genetics
Proto-Oncogene Proteins B-raf*/metabolism
Proto-Oncogene Proteins c-mdm2*/genetics
Proto-Oncogene Proteins c-mdm2*/metabolism
Animals ; Humans ; Mice ; In Situ Hybridization, Fluorescence ; Mutation ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lineage-specific intolerance to oncogenic drivers restricts histological transformation.
Autorzy:
Gardner EE; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.
Earlie EM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY.
Li K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.
Thomas J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.
Hubisz MJ; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY.; Bioinformatics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY.
Stein BD; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.; Department of Medicine, Weill Cornell Medicine, New York, NY.
Zhang C; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY.
Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.; Department of Medicine, Weill Cornell Medicine, New York, NY.
Laughney AM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY.
Varmus H; Meyer Cancer Center, Weill Cornell Medicine, New York, NY.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 09; Vol. 383 (6683), pp. eadj1415. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/pathology
Adenocarcinoma of Lung*/therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Lung Neoplasms*/therapy
Small Cell Lung Carcinoma*/genetics
Small Cell Lung Carcinoma*/pathology
Small Cell Lung Carcinoma*/therapy
Proto-Oncogene Proteins c-myc*/genetics
Proto-Oncogene Proteins c-akt*/genetics
Humans ; Epithelial Cells/pathology ; Lung/pathology ; Oncogenes ; Cell Lineage ; Molecular Targeted Therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 63423

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