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Wyszukujesz frazę ""ORAI1 Protein"" wg kryterium: Temat


Tytuł:
Orai1α and Orai1β support calcium entry and mammosphere formation in breast cancer stem cells.
Autorzy:
Jardin I; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain. .
Alvarado S; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain.
Jimenez-Velarde V; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain.
Nieto-Felipe J; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain.
Lopez JJ; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain.
Salido GM; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain.
Smani T; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.; Departamento de Fisiologia Medica y Biofisica, Facultad de Medicina, Universidad de Sevilla, Seville, Spain.
Rosado JA; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), Universidad de Extremadura, 10003, Caceres, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 09; Vol. 13 (1), pp. 19471. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium*/metabolism
Triple Negative Breast Neoplasms*
Animals ; Humans ; Calcium Channels/metabolism ; Calcium Signaling/physiology ; Calcium, Dietary/metabolism ; Neoplastic Stem Cells/metabolism ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; Stromal Interaction Molecule 1/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1.
Autorzy:
Yang L; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
Ottenheijm R; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
Worley P; The Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Freichel M; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
Camacho Londoño JE; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
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Źródło:
Cells [Cells] 2022 Oct 14; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets*/metabolism
Calcium*/metabolism
ORAI1 Protein*/metabolism
Animals ; Female ; Male ; Mice ; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/pharmacology ; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/metabolism ; Adenosine Diphosphate/metabolism ; Adenosine Triphosphatases/metabolism ; Calcium Channels/metabolism ; Calcium Signaling ; Collagen/metabolism ; Peptides/metabolism ; Stromal Interaction Molecule 1/metabolism ; Thapsigargin/pharmacology ; Thrombin/pharmacology ; Thromboxane A2/metabolism
Czasopismo naukowe
Tytuł:
Activation of STIM1/Orai1‑mediated SOCE in sepsis‑induced myocardial depression.
Autorzy:
Ye J; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Li M; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Li Q; Ultrasound Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Jia Z; Ultrasound Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Hu X; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Zhao G; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Zhi S; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Hong G; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Lu Z; Emergency Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Aug; Vol. 26 (2). Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling*
Heart*/physiopathology
ORAI1 Protein*/genetics
ORAI1 Protein*/metabolism
Sepsis*/complications
Stromal Interaction Molecule 1*/genetics
Stromal Interaction Molecule 1*/metabolism
Animals ; Calcium/metabolism ; Mice ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Neutrophil-specific ORAI1 Calcium Channel Inhibition Reduces Pancreatitis-associated Acute Lung Injury.
Autorzy:
Niu M; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Zhang X; Center for Biomarker Discovery and Validation, National Infrastructures for Translational Medicine (PUMCH), Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Wu Z; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Li B; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Bao J; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Dai J; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Yang Z; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
Zeng Y; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Li L; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Pandol S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Sutton R; Liverpool Pancreatitis Research Group, Liverpool University Hospitals NHS Foundation Trust and Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.
Wen L; Center for Biomarker Discovery and Validation, National Infrastructures for Translational Medicine (PUMCH), Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.; State Key Laboratory of Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
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Źródło:
Function (Oxford, England) [Function (Oxf)] 2023 Oct 23; Vol. 5 (1), pp. zqad061. Date of Electronic Publication: 2023 Oct 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/drug therapy
Pancreatitis*/complications
Animals ; Humans ; Mice ; Acute Disease ; Neutrophils/metabolism ; ORAI1 Protein/genetics
Czasopismo naukowe
Tytuł:
Silencing of the Ca Channel ORAI1 Improves the Multi-Systemic Phenotype of Tubular Aggregate Myopathy (TAM) and Stormorken Syndrome (STRMK) in Mice.
Autorzy:
Silva-Rojas R; IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, 67404 Illkirch, France.
Pérez-Guàrdia L; IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, 67404 Illkirch, France.
Lafabrie E; IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, 67404 Illkirch, France.
Moulaert D; Institut Clinique de la Souris (ICS), 67404 Illkirch, France.
Laporte J; IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, 67404 Illkirch, France.
Böhm J; IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, 67404 Illkirch, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 23; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelet Disorders*/genetics
Blood Platelet Disorders*/metabolism
Dyslexia*/genetics
Dyslexia*/metabolism
Ichthyosis*/genetics
Ichthyosis*/metabolism
Myopathies, Structural, Congenital*/genetics
Myopathies, Structural, Congenital*/metabolism
Myopathies, Structural, Congenital*/pathology
ORAI1 Protein*/genetics
ORAI1 Protein*/metabolism
Animals ; Calcium/metabolism ; Erythrocytes, Abnormal ; Mice ; Migraine Disorders/genetics ; Migraine Disorders/metabolism ; Miosis ; Muscle Fatigue ; Phenotype ; Spleen/abnormalities ; Spleen/metabolism ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism
SCR Disease Name:
Stormorken Syndrome
Czasopismo naukowe
Tytuł:
Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblasts.
Autorzy:
Guo Y; Department of spinal surgery, Hong Hui Hospital, Xi'an Jiao Tong University, Xi'an, Shaanxi, 710054, People's Republic of China. .
Fan J; Department of bone microsurgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, People's Republic of China.
Liu S; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, People's Republic of China. orth_.
Hao D; Department of spinal surgery, Hong Hui Hospital, Xi'an Jiao Tong University, Xi'an, Shaanxi, 710054, People's Republic of China. .
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Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2022 Apr 11; Vol. 23 (1), pp. 347. Date of Electronic Publication: 2022 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Checkpoints*
NF-kappa B*/metabolism
ORAI1 Protein*/genetics
ORAI1 Protein*/metabolism
Osteoblasts*/metabolism
3T3 Cells ; Animals ; Cell Cycle ; Cell Proliferation ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Down-Regulation ; Mice ; RNA, Small Interfering/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł:
TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination.
Autorzy:
Zhou Q; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.; Department of urology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Chen X; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Yao K; Department of urology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Zhang Y; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
He H; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.; Department of Radiation Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Huang H; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Chen H; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Peng S; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Huang M; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Cheng L; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Zhang Q; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Xie R; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Li K; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China. .; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. .
Lin T; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China. .; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. .; Guangdong Provincial Clinical Research Center for Urological Diseases, Guangzhou, 510120, Guangdong, China. .
Huang H; Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th yanjiangxi road, Guangzhou, 510120, China. .; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. .; Department of Urology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, 511518, Guangdong, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Aug 05; Vol. 42 (1), pp. 195. Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*/metabolism
Prostatic Neoplasms*/genetics
Male ; Humans ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/chemistry ; Stromal Interaction Molecule 1/metabolism ; Calcium Channels/metabolism ; Ubiquitination ; Calcium Signaling ; ORAI1 Protein/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Tripartite Motif Proteins/metabolism ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Tetraspanins/genetics ; Tetraspanins/metabolism
Czasopismo naukowe
Tytuł:
Immune Synapse Residency of Orai1 Alters Ca Response of T Cells.
Autorzy:
Voros O; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, 4032 Debrecen, Hungary.
Panyi G; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, 4032 Debrecen, Hungary.
Hajdu P; Department of Biophysics and Cell Biology, Faculty of Dentistry, University of Debrecen, Nagyerdei krt. 98, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 26; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling/*immunology
Immunological Synapses/*metabolism
ORAI1 Protein/*metabolism
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Adaptive Immunity ; Discs Large Homolog 1 Protein/antagonists & inhibitors ; Discs Large Homolog 1 Protein/genetics ; Discs Large Homolog 1 Protein/metabolism ; Endoplasmic Reticulum/metabolism ; Gene Knockdown Techniques ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Immunological Synapses/genetics ; Immunological Synapses/immunology ; Jurkat Cells ; Kinetics ; Lymphocyte Activation ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; ORAI1 Protein/chemistry ; ORAI1 Protein/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Sequence Deletion ; Stromal Interaction Molecule 1/antagonists & inhibitors ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism
Czasopismo naukowe
Tytuł:
High affinity associations with α-SNAP enable calcium entry via Orai1 channels.
Autorzy:
Ramanagoudr-Bhojappa R; Cancer Genetics and Comparative Genomics Branch, NHGRI, Bethesda, MD, United States of America.
Miao Y; GEiC, Washington University in St. Louis, School of Medicine, St. Louis, MO, United States of America.
Vig M; Tata Institute of Fundamental Research, Hyderabad, India.
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Źródło:
PloS one [PLoS One] 2021 Oct 15; Vol. 16 (10), pp. e0258670. Date of Electronic Publication: 2021 Oct 15 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Proteins/*genetics
Neoplasm Proteins/*metabolism
ORAI1 Protein/*genetics
ORAI1 Protein/*metabolism
Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins/*metabolism
Stromal Interaction Molecule 1/*genetics
Stromal Interaction Molecule 1/*metabolism
Animals ; Binding Sites ; Cell Line ; Cloning, Molecular ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Gene Knockout Techniques ; HEK293 Cells ; Humans ; Mice ; Mutation ; Neoplasm Proteins/chemistry ; ORAI1 Protein/chemistry ; Protein Binding ; Stromal Interaction Molecule 1/chemistry
Czasopismo naukowe
Tytuł:
Anti-Inflammatory Effect of Licochalcone A via Regulation of ORAI1 and K Channels in T-Lymphocytes.
Autorzy:
Phan HTL; Department of Physiology, Dongguk University College of Medicine, 123 Dongdae-ro, Gyeongju 38066, Korea.; Channelopathy Research Center (CRC), Dongguk University College of Medicine, 32 Dongguk-ro, Goyang 10326, Korea.
Kim HJ; Channelopathy Research Center (CRC), Dongguk University College of Medicine, 32 Dongguk-ro, Goyang 10326, Korea.
Jo S; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, 85 Songdogwahak-ro, Incheon 21983, Korea.
Kim WK; Channelopathy Research Center (CRC), Dongguk University College of Medicine, 32 Dongguk-ro, Goyang 10326, Korea.; Department of Internal Medicine Graduate School of Medicine, Dongguk University, 27 Dongguk-ro, Goyang 10326, Korea.
Namkung W; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, 85 Songdogwahak-ro, Incheon 21983, Korea.
Nam JH; Department of Physiology, Dongguk University College of Medicine, 123 Dongdae-ro, Gyeongju 38066, Korea.; Channelopathy Research Center (CRC), Dongguk University College of Medicine, 32 Dongguk-ro, Goyang 10326, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 07; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Chalcones/*pharmacology
Gene Expression Regulation/*drug effects
Intermediate-Conductance Calcium-Activated Potassium Channels/*antagonists & inhibitors
Kv1.3 Potassium Channel/*antagonists & inhibitors
ORAI1 Protein/*antagonists & inhibitors
T-Lymphocytes/*drug effects
Calcium/metabolism ; Calcium Signaling ; HEK293 Cells ; Humans ; Intermediate-Conductance Calcium-Activated Potassium Channels/genetics ; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism ; Jurkat Cells ; Kv1.3 Potassium Channel/genetics ; Kv1.3 Potassium Channel/metabolism ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
The calcium channel Orai1 is required for osteoblast development: Studies in a chimeric mouse with variable in vivo Runx-cre deletion of Orai-1.
Autorzy:
Robinson LJ; Departments of Pathology, Anatomy and Laboratory Medicine, and of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States of America.
Soboloff J; Fels Cancer Institute for Personalized Medicine, Department of Cancer and Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States of America.
Tourkova IL; Departments of Pathology and of Cell Biology, The Pittsburgh VA Medical Center and the University of Pittsburgh, Pittsburgh, PA, United States of America.
Larrouture QC; Departments of Pathology and of Cell Biology, The Pittsburgh VA Medical Center and the University of Pittsburgh, Pittsburgh, PA, United States of America.
Onwuka KM; Departments of Pathology and of Cell Biology, The Pittsburgh VA Medical Center and the University of Pittsburgh, Pittsburgh, PA, United States of America.
Papachristou DJ; Departments of Pathology and of Cell Biology, The Pittsburgh VA Medical Center and the University of Pittsburgh, Pittsburgh, PA, United States of America.; Laboratory of Bone and Soft Tissue Studies, Department of Anatomy-Histology-Embryology, University Patras Medical School, Patras, Greece.
Gross S; Fels Cancer Institute for Personalized Medicine, Department of Cancer and Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States of America.
Hooper R; Fels Cancer Institute for Personalized Medicine, Department of Cancer and Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States of America.
Samakai E; Fels Cancer Institute for Personalized Medicine, Department of Cancer and Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States of America.
Worley PF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Liu P; Institute of Comparative Molecular Endocrinology, Helmholtzstraße, Ulm, Germany.
Tuckermann J; Institute of Comparative Molecular Endocrinology, Helmholtzstraße, Ulm, Germany.
Witt MR; Departments of Pathology, Anatomy and Laboratory Medicine, and of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States of America.
Blair HC; Departments of Pathology and of Cell Biology, The Pittsburgh VA Medical Center and the University of Pittsburgh, Pittsburgh, PA, United States of America.
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Źródło:
PloS one [PLoS One] 2023 May 11; Vol. 18 (5), pp. e0264596. Date of Electronic Publication: 2023 May 11 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Calcium Channels*/genetics
Calcium Channels*/metabolism
Core Binding Factor Alpha 1 Subunit*/genetics
Core Binding Factor Alpha 1 Subunit*/metabolism
Osteoblasts*/metabolism
Animals ; Mice ; Calcium/metabolism ; Mice, Knockout ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism
Czasopismo naukowe
Tytuł:
Impact of SOCE Abolition by ORAI1 Knockout on the Proliferation, Adhesion, and Migration of HEK-293 Cells.
Autorzy:
Bokhobza A; Inserm U1003, Laboratory of Cell Physiology, Université de Lille, 59650 Villeneuve d'Ascq, France.
Ziental-Gelus N; Inserm U1003, Laboratory of Cell Physiology, Université de Lille, 59650 Villeneuve d'Ascq, France.
Allart L; Inserm U1003, Laboratory of Cell Physiology, Université de Lille, 59650 Villeneuve d'Ascq, France.
Iamshanova O; Inserm U1003, Laboratory of Cell Physiology, Université de Lille, 59650 Villeneuve d'Ascq, France.
Vanden Abeele F; Inserm U1003, Laboratory of Cell Physiology, Université de Lille, 59650 Villeneuve d'Ascq, France.
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Źródło:
Cells [Cells] 2021 Nov 04; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Movement*
Gene Knockout Techniques*
Calcium/*metabolism
ORAI1 Protein/*deficiency
Calcium Channels/genetics ; Calcium Channels/metabolism ; Cell Adhesion ; Cell Proliferation ; Genome, Human ; HEK293 Cells ; Humans ; ORAI1 Protein/metabolism ; ORAI2 Protein/genetics ; ORAI2 Protein/metabolism
Czasopismo naukowe
Tytuł:
Effect of MgCl 2 and GdCl 3 on ORAI1 Expression and Store-Operated Ca Entry in Megakaryocytes.
Autorzy:
Zhou K; Department of Pharmacology, Experimental Therapy & Toxicology, Eberhard Karls University, 72074 Tübingen, Germany.
Zhu X; Department of Pharmacology, Experimental Therapy & Toxicology, Eberhard Karls University, 72074 Tübingen, Germany.
Ma K; Department of Pharmacology, Experimental Therapy & Toxicology, Eberhard Karls University, 72074 Tübingen, Germany.
Liu J; Institute of Preventive Veterinary Medicine, Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.
Nürnberg B; Department of Pharmacology, Experimental Therapy & Toxicology, Eberhard Karls University, 72074 Tübingen, Germany.
Gawaz M; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Lang F; Department of Vegetative and Clinical Physiology, Eberhard Karls University, 72074 Tübingen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 24; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling*
Gadolinium/*pharmacology
Magnesium Chloride/*pharmacology
Megakaryocytes/*drug effects
ORAI1 Protein/*metabolism
Cells, Cultured ; Humans ; Immediate-Early Proteins/genetics ; Immediate-Early Proteins/metabolism ; Megakaryocytes/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; ORAI1 Protein/genetics ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis.
Autorzy:
Hodeify R; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.; Department of Biotechnology, American University of Ras Al Khaimah, Ras al Khaimah, UAE.
Dib M; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Alcantara-Adap E; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Courjaret R; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Nader N; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Reyes CZ; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.; Lehigh Valley Health Network, Allentown, PA, USA.
Hammad AS; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
Hubrack S; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.; Sidra Medicine, Doha, Qatar.
Yu F; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Machaca K; Department of Physiology and Biophysics, Ca2+ signaling Group, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 27; Vol. 11 (1), pp. 2290. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Meiosis/*physiology
ORAI1 Protein/*metabolism
Animals ; Calcium/metabolism ; Calcium Channels/genetics ; Calcium Channels/metabolism ; Calcium Signaling/genetics ; Calcium Signaling/physiology ; Caveolin 1/genetics ; Caveolin 1/metabolism ; Clathrin/genetics ; Clathrin/metabolism ; Endocytosis/genetics ; Endocytosis/physiology ; Female ; Meiosis/genetics ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Microscopy, Confocal ; Mutation/genetics ; ORAI1 Protein/genetics ; Xenopus laevis ; rab5 GTP-Binding Proteins/genetics ; rab5 GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
Searching for Mechanisms Underlying the Assembly of Calcium Entry Units: The Role of Temperature and pH.
Autorzy:
Girolami B; DMSI, Department of Medicine and Aging Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Serano M; DMSI, Department of Medicine and Aging Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Di Fonso A; DMSI, Department of Medicine and Aging Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Paolini C; DNISC, Department of Neuroscience and Clinical Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Pietrangelo L; DMSI, Department of Medicine and Aging Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Protasi F; DMSI, Department of Medicine and Aging Sciences & CAST, Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 10; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*/metabolism
Muscle, Skeletal*/metabolism
Mice ; Animals ; Temperature ; Muscle Fibers, Skeletal/metabolism ; Sarcoplasmic Reticulum/metabolism ; Calcium, Dietary ; Hydrogen-Ion Concentration ; ORAI1 Protein ; Stromal Interaction Molecule 1
Czasopismo naukowe
Tytuł:
The Molecular Heterogeneity of Store-Operated Ca -Selective to Non-Selective Cation Currents.
Autorzy:
Moccia F; Laboratory of General Physiology, Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Brunetti V; Laboratory of General Physiology, Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Perna A; Department of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.
Guerra G; Department of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.
Soda T; Department of Health Sciences, University of Magna Graecia, 88100 Catanzaro, Italy.
Berra-Romani R; Department of Biomedicine, School of Medicine, Benemérita Universidad Autónoma de Puebla, Puebla 72410, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 07; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Calcium Channels*/metabolism
Endothelial Cells*/metabolism
Animals ; Cattle ; Mice ; Rats ; Humans ; TRPC Cation Channels/metabolism ; Stromal Interaction Molecule 1/metabolism ; Calcium/metabolism ; ORAI1 Protein/metabolism ; Calcium Signaling/physiology
Czasopismo naukowe
Tytuł:
Similarities and Differences between the Orai1 Variants: Orai1α and Orai1β.
Autorzy:
Jardin I; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Berna-Erro A; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Nieto-Felipe J; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Macias A; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Sanchez-Collado J; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Lopez JJ; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Salido GM; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
Rosado JA; Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, 10003 Caceres, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 23; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Calcium*/metabolism
Calcium Channels*/genetics
Calcium Channels*/metabolism
Animals ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; TRPC Cation Channels/metabolism ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism ; Ion Transport ; Calcium Signaling
Czasopismo naukowe
Tytuł:
Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling.
Autorzy:
Segin S; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site, 69120 Heidelberg/Mannheim, Germany.
Berlin M; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site, 69120 Heidelberg/Mannheim, Germany.
Richter C; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.
Flockerzi RMV; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site, 69120 Heidelberg/Mannheim, Germany.; Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421 Homburg, Germany.
Worley P; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Freichel M; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site, 69120 Heidelberg/Mannheim, Germany.
Londoño JEC; Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site, 69120 Heidelberg/Mannheim, Germany.
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Źródło:
Cells [Cells] 2020 Apr 28; Vol. 9 (5). Date of Electronic Publication: 2020 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myocytes, Cardiac/*metabolism
ORAI1 Protein/*genetics
ORAI1 Protein/*metabolism
Angiotensin II/metabolism ; Angiotensins/metabolism ; Animals ; Calcium/metabolism ; Calcium Signaling ; Carrier Proteins/metabolism ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microfilament Proteins/metabolism ; Muscle Proteins/metabolism ; Myocardium/metabolism ; Myocytes, Cardiac/physiology ; ORAI1 Protein/physiology ; Stromal Interaction Molecule 1/metabolism ; Ventricular Remodeling/genetics ; Ventricular Remodeling/physiology
Czasopismo naukowe
Tytuł:
Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.
Autorzy:
Schild A; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Bhardwaj R; Department of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Wenger N; Department of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Tscherrig D; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Kandasamy P; Department of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Dernič J; Department of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Baur R; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Hediger MA; Department of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Lochner M; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 05; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Boron Compounds/*pharmacology
Breast Neoplasms/*drug therapy
Neoplasm Proteins/*genetics
ORAI1 Protein/*genetics
Stromal Interaction Molecule 1/*genetics
Stromal Interaction Molecules/*genetics
Animals ; Boron Compounds/chemical synthesis ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Calcium/metabolism ; Calcium Signaling/drug effects ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/genetics ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Multiprotein Complexes/antagonists & inhibitors ; Multiprotein Complexes/genetics ; Neoplasm Proteins/antagonists & inhibitors ; ORAI1 Protein/chemistry ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Stromal Interaction Molecule 1/antagonists & inhibitors ; Stromal Interaction Molecules/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes.
Autorzy:
Shrestha N; Gottfried Schatz Research Center-Biophysics, Medical University of Graz, Graz, Austria.
Bacsa B; Gottfried Schatz Research Center-Biophysics, Medical University of Graz, Graz, Austria.
Ong HL; Secretory Physiology Section, NIDCR, NIH, Bethesda, Maryland, United States of America.
Scheruebel S; Gottfried Schatz Research Center-Biophysics, Medical University of Graz, Graz, Austria.
Bischof H; Gottfried Schatz Research Center-Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Malli R; Gottfried Schatz Research Center-Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Ambudkar IS; Secretory Physiology Section, NIDCR, NIH, Bethesda, Maryland, United States of America.
Groschner K; Gottfried Schatz Research Center-Biophysics, Medical University of Graz, Graz, Austria.
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Źródło:
PLoS biology [PLoS Biol] 2020 Apr 24; Vol. 18 (4), pp. e3000700. Date of Electronic Publication: 2020 Apr 24 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Ion Channels/*metabolism
Neoplasm Proteins/*metabolism
ORAI1 Protein/*metabolism
Stromal Interaction Molecule 1/*metabolism
Animals ; Calcium Signaling/physiology ; Cell Membrane/metabolism ; Endoplasmic Reticulum/metabolism ; HEK293 Cells ; Humans ; Male ; Mice, Inbred C57BL ; Multiprotein Complexes/metabolism ; Neoplasm Proteins/genetics ; ORAI1 Protein/genetics ; Patch-Clamp Techniques ; Ryanodine Receptor Calcium Release Channel/metabolism ; Stromal Interaction Molecule 1/genetics
Czasopismo naukowe

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