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Podgląd okładki
Tytuł :
Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson's disease.
Autorzy :
Hou YF; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Shan C; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Zhuang SY; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhuang QQ; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ghosh A; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhu KC; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Kong XK; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Wang SM; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Gong YL; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, 200240, China.
Yang YY; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Tao B; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Sun LH; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Zhao HY; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Guo XZ; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Wang WQ; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Ning G; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China.
Gu YY; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China. .
Li ST; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, 200240, China. .
Liu JM; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, 200025, China. .
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Źródło :
Microbiome [Microbiome] 2021 Jan 31; Vol. 9 (1), pp. 34. Date of Electronic Publication: 2021 Jan 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Gastrointestinal Microbiome/*physiology
Neuroprotective Agents/*pharmacology
Osteocalcin/*pharmacology
Parkinson Disease/*drug therapy
Parkinson Disease/*metabolism
Propionates/*metabolism
Animals ; Anti-Bacterial Agents/pharmacology ; Disease Models, Animal ; Disease Progression ; Dopaminergic Neurons/drug effects ; Fecal Microbiota Transplantation ; Gastrointestinal Microbiome/drug effects ; Infusions, Parenteral ; Male ; Mice ; Neuroprotective Agents/administration & dosage ; Osteocalcin/administration & dosage ; Oxidopamine ; Parkinson Disease/microbiology ; Parkinson Disease/physiopathology ; Receptors, G-Protein-Coupled/agonists ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Serum Osteocalcin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Recipients.
Autorzy :
Lin L; Division of Gastroenterology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.
Chiu LT; Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.
Lee MC; Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.; School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.
Hsu BG; Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.; School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2020 Aug 09; Vol. 56 (8). Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Osteocalcin/*analysis
Vascular Stiffness/*physiology
Adult ; Body Mass Index ; Female ; Humans ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/methods ; Male ; Middle Aged ; Osteocalcin/blood ; Pulse Wave Analysis/instrumentation ; Pulse Wave Analysis/methods ; Taiwan/epidemiology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The structural role of osteocalcin in bone biomechanics and its alteration in Type-2 Diabetes.
Autorzy :
Tavakol M; Biomedical Engineering and Biomechanics Research Centre, School of Engineering, College of Science and Engineering, National University of Ireland Galway, Galway, Ireland.
Vaughan TJ; Biomedical Engineering and Biomechanics Research Centre, School of Engineering, College of Science and Engineering, National University of Ireland Galway, Galway, Ireland. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 14; Vol. 10 (1), pp. 17321. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Diseases, Metabolic/*etiology
Bone and Bones/*physiology
Diabetes Mellitus, Type 2/*metabolism
Osteocalcin/*physiology
Adsorption ; Amino Acid Motifs ; Amino Acid Sequence ; Arginine/chemistry ; Biomechanical Phenomena ; Bone Diseases, Metabolic/metabolism ; Bone Diseases, Metabolic/physiopathology ; Diabetes Mellitus, Type 2/complications ; Durapatite/chemistry ; Humans ; Hydrogen Bonding ; Molecular Dynamics Simulation ; Osteocalcin/chemistry ; Protein Conformation, alpha-Helical ; Structure-Activity Relationship ; Thermodynamics
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Efficient mineralization and osteogenic gene overexpression of mesenchymal stem cells on decellularized spinach leaf scaffold.
Autorzy :
Salehi A; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran.
Mobarhan MA; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran.
Mohammadi J; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran. Electronic address: .
Shahsavarani H; Department of Cell and Molecular Sciences, Faculty of Life science and Biotechnology, Shahid Beheshti University, Tehran, Iran; Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran. Electronic address: .
Shokrgozar MA; National Cell Bank of Iran, Pasteur Institute of Iran, No. 69, Pasteur Ave, Tehran 1316943551, Iran.
Alipour A; Department of Nanobiotechnology, Pasteur Institute of Iran, No. 69, Pasteur Ave, Tehran 1316943551, Iran.
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144852. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Mesenchymal Stem Cells/*metabolism
Osteoblasts/*metabolism
Osteocalcin/*genetics
Plant Leaves/*chemistry
Tissue Scaffolds/*chemistry
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Biomineralization ; Calcium/metabolism ; Cell Line ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Humans ; Mesenchymal Stem Cells/cytology ; Osteoblasts/cytology ; Osteocalcin/metabolism ; Spinacia oleracea/chemistry
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Computational Nanomechanics of Noncollagenous Interfibrillar Interface in Bone.
Autorzy :
Wang Y; Department of Mechanical Engineering, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States.
Morsali R; Department of Mechanical Engineering, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States.
Dai Z; College of Material and Textile Engineering, Jiaxing University, Jiaxing 314001, People's Republic of China.
Minary-Jolandan M; Department of Mechanical Engineering, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States.
Qian D; Department of Mechanical Engineering, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 Jun 03; Vol. 12 (22), pp. 25363-25373. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Biomechanical Phenomena*
Bone and Bones/*chemistry
Osteocalcin/*chemistry
Osteopontin/*chemistry
Animals ; Durapatite/chemistry ; Durapatite/metabolism ; Fish Proteins/chemistry ; Fish Proteins/metabolism ; Fishes ; Molecular Dynamics Simulation ; Osteocalcin/metabolism ; Osteopontin/metabolism ; Protein Binding ; Shear Strength ; Stress, Mechanical
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Independent validation of experimental results requires timely and unrestricted access to animal models and reagents.
Autorzy :
Diegel CR; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Hann S; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Ayturk UM; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.; Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America.
Hu JCW; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Lim KE; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Droscha CJ; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Madaj ZB; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Foxa GE; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Izaguirre I; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Robling AG; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Warman ML; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Williams BO; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
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Corporate Authors :
VAI Vivarium and Transgenics Core
Źródło :
PLoS genetics [PLoS Genet] 2020 Jun 26; Vol. 16 (6), pp. e1008940. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Models, Animal*
Reproducibility of Results*
Hormones/*metabolism
Osteocalcin/*metabolism
Animals ; Bone and Bones/metabolism ; Hormones/genetics ; Humans ; Mice ; Mice, Knockout ; Osteocalcin/genetics ; Rats ; Rats, Transgenic ; Species Specificity
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
The facts of the matter: What is a hormone?
Autorzy :
Karsenty G; Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Jun 26; Vol. 16 (6), pp. e1008938. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hormones*
Osteocalcin*
Terminology as Topic*
Animals ; Bone and Bones/metabolism ; Humans ; Mice ; Models, Animal ; Species Specificity
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.
Autorzy :
Moriishi T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Ozasa R; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Ishimoto T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Nakano T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Hasegawa T; Department of Developmental Biology of Hard Tissue, Division of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Miyazaki T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Liu W; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Institute of Genetics and Cytology, Northeast Normal University, Changchun, China.
Fukuyama R; Laboratory of Pharmacology, Hiroshima International University, Kure, Japan.
Wang Y; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; College of Life and Environmental Science, Hangzhou Normal University, Hangzhou, China.
Komori H; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Qin X; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Amizuka N; Department of Developmental Biology of Hard Tissue, Division of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Komori T; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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Źródło :
PLoS genetics [PLoS Genet] 2020 May 28; Vol. 16 (5), pp. e1008586. Date of Electronic Publication: 2020 May 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apatites/*metabolism
Calcification, Physiologic/*genetics
Carbohydrate Metabolism/*genetics
Glucose/*metabolism
Muscle, Skeletal/*growth & development
Osteocalcin/*physiology
Testosterone/*biosynthesis
Animals ; Apatites/chemistry ; Bone and Bones/metabolism ; Collagen/metabolism ; Crystallization ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle Development/genetics ; Muscle, Skeletal/metabolism ; Organ Size/genetics ; Osteoblasts/metabolism ; Osteocalcin/genetics ; Osteogenesis/genetics ; Testis/growth & development ; Testis/metabolism
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
An osteocalcin-deficient mouse strain without endocrine abnormalities.
Autorzy :
Diegel CR; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Hann S; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Ayturk UM; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.; Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America.
Hu JCW; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Lim KE; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Droscha CJ; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Madaj ZB; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Foxa GE; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Izaguirre I; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Transgenics Core VVA; Vivarium and Transgenics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Paracha N; Department of Biology, Brooklyn College, Brooklyn, New York, United States of America.
Pidhaynyy B; Department of Biology, Brooklyn College, Brooklyn, New York, United States of America.
Dowd TL; Department of Chemistry, Brooklyn College, Brooklyn, New York, United States of America.; Ph.D. Program in Chemistry and Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, New York, United States of America.
Robling AG; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Warman ML; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Williams BO; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Pokaż więcej
Źródło :
PLoS genetics [PLoS Genet] 2020 May 28; Vol. 16 (5), pp. e1008361. Date of Electronic Publication: 2020 May 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endocrine System/*physiology
Osteocalcin/*genetics
Animals ; Bone Density/genetics ; Bone and Bones/metabolism ; Endocrine System/metabolism ; Female ; Fertility/genetics ; Insulin Resistance/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Osteocalcin/deficiency
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease.
Autorzy :
Toya, Takumi (AUTHOR)
Ozcan, Ilke (AUTHOR)
Corban, Michel T. (AUTHOR)
Sara, Jaskanwal D. (AUTHOR)
Marietta, Eric V. (AUTHOR)
Ahmad, Ali (AUTHOR)
Horwath, Irina E. (AUTHOR)
Loeffler, Darrell L. (AUTHOR)
Murray, Joseph A. (AUTHOR)
Lerman, Lilach O. (AUTHOR)
Lerman, Amir (AUTHOR)
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Źródło :
PLoS ONE. 3/25/2021, Vol. 16 Issue 3, p1-16. 16p.
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Autorzy :
Zheng J; Department of Endodontics, Key Laboratory of Oral Clinical Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhu X; Department of Endodontics, Stomatological Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
He Y; Department of Endodontics, Stomatological Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Hou S; Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Liu T; Department of Endodontics, Key Laboratory of Oral Clinical Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhi K; Department of Oral and Maxillofacial Surgery, Key Laboratory of Oral Clinical Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Hou T; Department of Endodontics, Stomatological Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Gao L; Department of Oral and Maxillofacial Surgery, Key Laboratory of Oral Clinical Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
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Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2021 Feb; Vol. 1485 (1), pp. 56-70. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*physiology
Cyclin-Dependent Kinase 8/*genetics
Hypoxia/*genetics
Mesenchymal Stem Cells/*physiology
Osteogenesis/*physiology
Periodontal Ligament/*cytology
RNA, Circular/*genetics
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Apoptosis/drug effects ; Autophagy/drug effects ; Autophagy/physiology ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cobalt/pharmacology ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Cyclin-Dependent Kinase 8/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Endoplasmic Reticulum Stress/physiology ; Humans ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mesenchymal Stem Cells/drug effects ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteogenesis/drug effects ; Periodontal Ligament/drug effects ; Periodontitis/genetics ; Periodontitis/metabolism ; RNA, Circular/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The effect of exercise training on osteocalcin, adipocytokines, and insulin resistance: a systematic review and meta-analysis of randomized controlled trials.
Autorzy :
Mohammad Rahimi GR; Department of Sports Sciences, Vahdat Institute of Higher Education, Torbat-e-Jam, Iran. .
Niyazi A; Mashhad, Iran.
Alaee S; Department of Physical Education, Islamic Azad University, Neyshabur Branch, Neyshabur, Iran.
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Źródło :
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA [Osteoporos Int] 2021 Feb; Vol. 32 (2), pp. 213-224. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms :
Insulin Resistance*
Adipokines ; Adult ; Blood Glucose ; Exercise ; Humans ; Insulin ; Osteocalcin ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Osteocalcin in acute stress response: from the perspective of cardiac diseases.
Autorzy :
Tian A; Department of Cardiology, Beijing Geriatric Hospital, Beijing, China.
Yang C; Department of Cardiology and Macrovascular Disease, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jin Z; Department of Cardiology and Macrovascular Disease, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło :
Current medical research and opinion [Curr Med Res Opin] 2020 Apr; Vol. 36 (4), pp. 545-546. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji :
Journal Article
MeSH Terms :
Bone and Bones/*physiology
Myocardial Infarction/*physiopathology
Osteocalcin/*physiology
Stress, Physiological/*physiology
Acute Disease ; Animals ; Autonomic Nervous System/physiopathology ; Heart Failure/physiopathology ; Humans ; Mice ; Myocardial Infarction/drug therapy ; Osteocalcin/blood
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway.
Autorzy :
Zhang XL; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Wang YN; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Ma LY; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.
Liu ZS; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.
Ye F; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. .
Yang JH; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 Mar; Vol. 41 (3), pp. 383-393. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Insulin/*metabolism
Liver/*metabolism
Osteocalcin/*metabolism
Administration, Oral ; Animals ; Disease Models, Animal ; Female ; Glucose Tolerance Test ; Lipid Metabolism ; Mice ; Mice, Obese ; Osteocalcin/administration & dosage ; Signal Transduction
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Association of Bone Mineral Density to Cerebral Small Vessel Disease Burden.
Autorzy :
Kim JM; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Park KY; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea. .
Kim HR; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Ahn HY; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Pantoni L; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Park MS; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea. .
Han SH; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Jung HB; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
Bae J; From the Department of Neurology (J.-M.K.), Seoul National University Hospital; Departments of Neurology (K.-Y.P., S.-H.H., H.-B.J., J.B.), Laboratory Medicine (H.R.K.), and Internal Medicine (H.Y.A.), Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea; Luigi Sacco Stroke and Dementia Lab (L.P.), Department of Biomedical and Clinical Sciences, University of Milan, Italy; and Department of Neurology (M.-S.P.), Seoul Hospital Ewha Womans University College of Medicine, South Korea.
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Źródło :
Neurology [Neurology] 2021 Mar 02; Vol. 96 (9), pp. e1290-e1300. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Density*
Cerebral Small Vessel Diseases/*pathology
Absorptiometry, Photon ; Aged ; Aged, 80 and over ; Bone Diseases, Metabolic/complications ; Brain/diagnostic imaging ; Cerebral Small Vessel Diseases/complications ; Cerebral Small Vessel Diseases/diagnostic imaging ; Female ; Humans ; Intracranial Arteriosclerosis/complications ; Intracranial Arteriosclerosis/diagnostic imaging ; Intracranial Hemorrhages/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; MicroRNAs/genetics ; Middle Aged ; Osteocalcin/blood ; Osteoporosis/complications ; Parathyroid Hormone/blood ; Stroke/diagnostic imaging ; Stroke/pathology ; White Matter/diagnostic imaging
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Sclerostin, preadipocyte factor-1 and bone mineral values in eumenorrheic adolescent athletes with different training patterns.
Autorzy :
Jürimäe J; Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, 18. Ülikooli St., 50090, Tartu, Estonia. .
Karvelyte V; Lithuanian Sports University, Kaunas, Lithuania.
Remmel L; Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, 18. Ülikooli St., 50090, Tartu, Estonia.
Tamm AL; Tartu Health Care College, Tartu, Estonia.
Purge P; Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, 18. Ülikooli St., 50090, Tartu, Estonia.
Gruodyte-Raciene R; Lithuanian Sports University, Kaunas, Lithuania.
Kamandulis S; Lithuanian Sports University, Kaunas, Lithuania.
Maasalu K; Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
Gracia-Marco L; PROFITH (PROmoting FITness and Health Through Physical Activity) Research Group, Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.
Tillmann V; Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
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Źródło :
Journal of bone and mineral metabolism [J Bone Miner Metab] 2021 Mar; Vol. 39 (2), pp. 245-252. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article
MeSH Terms :
Athletes*
Bone Density*
Physical Conditioning, Human*
Adaptor Proteins, Signal Transducing/*metabolism
Calcium-Binding Proteins/*metabolism
Membrane Proteins/*metabolism
Absorptiometry, Photon ; Adaptor Proteins, Signal Transducing/blood ; Adolescent ; Body Composition ; Calcification, Physiologic ; Calcium-Binding Proteins/blood ; Collagen Type I/blood ; Female ; Humans ; Membrane Proteins/blood ; Osteocalcin/blood ; Peptides/blood ; Regression Analysis
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Changes of bone turnover markers after elderly hip fracture surgery.
Autorzy :
Li XP; Department of Geriatrics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China.
Li XY; Department of Geriatrics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China.
Yang MH; Department of Trauma Orthopaedics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China.
Zhu SW; Department of Trauma Orthopaedics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China.
Wu XB; Department of Trauma Orthopaedics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China.
Zhang P; Department of Geriatrics, Beijing Jishuitan Hospital, the Fourth Medical College of Peking University, Beijing, 100035, China. .
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Źródło :
Journal of bone and mineral metabolism [J Bone Miner Metab] 2021 Mar; Vol. 39 (2), pp. 237-244. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Bone Remodeling*
Biomarkers/*blood
Hip Fractures/*blood
Hip Fractures/*surgery
Aged ; Aged, 80 and over ; Bone Density ; Collagen Type I/blood ; Female ; Follow-Up Studies ; Hip Fractures/physiopathology ; Humans ; Male ; Osteocalcin/blood ; Peptide Fragments/blood ; Peptides/blood ; Procollagen/blood
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Low serum levels of bone turnover markers are associated with the presence and severity of diabetic retinopathy in patients with type 2 diabetes mellitus.
Autorzy :
An Y; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Liu S; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Wang W; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Dong H; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Zhao W; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Ke J; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
Zhao D; Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Diabetes Research and Care, Beijing, China.
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Źródło :
Journal of diabetes [J Diabetes] 2021 Feb; Vol. 13 (2), pp. 111-123. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Remodeling/*physiology
Collagen Type I/*blood
Diabetes Mellitus, Type 2/*blood
Diabetic Retinopathy/*diagnosis
Osteocalcin/*blood
Peptide Fragments/*blood
Peptides/*blood
Procollagen/*blood
Biomarkers/blood ; Cross-Sectional Studies ; Diabetic Retinopathy/blood ; Female ; Humans ; Male ; Middle Aged ; Severity of Illness Index
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Iron Status in Elderly Women Impacts Myostatin, Adiponectin and Osteocalcin Levels Induced by Nordic Walking Training.
Autorzy :
Kortas J; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Ziemann E; Department of Athletics, Strength and Conditioning, Poznan University of Physical Education, 61-871 Poznan, Poland.
Juszczak D; Seventh Navy Hospital, 80-305 Gdansk, Poland.
Micielska K; Department of Anatomy and Anthropology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Kozłowska M; Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Prusik K; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Prusik K; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Antosiewicz J; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-210 Gdansk, Poland.
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Źródło :
Nutrients [Nutrients] 2020 Apr 17; Vol. 12 (4). Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Journal Article
MeSH Terms :
Adiponectin/*metabolism
Iron/*metabolism
Myostatin/*metabolism
Osteocalcin/*metabolism
Physical Conditioning, Human/*physiology
Walking/*physiology
Adiponectin/blood ; Aged ; Aging/metabolism ; Female ; Ferritins/blood ; Ferritins/metabolism ; Humans ; Iron/blood ; Middle Aged ; Myostatin/blood ; Osteocalcin/blood ; Postmenopause/metabolism ; Time Factors
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 24344

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