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Wyszukujesz frazę ""Odom DT"" wg kryterium: Autor


Tytuł :
Functional signatures of evolutionarily young CTCF binding sites.
Autorzy :
Azazi D; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Mudge JM; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Odom DT; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK.; German Cancer Research Center (DKFZ), Division Regulatory Genomics and Cancer Evolution, 69120, Heidelberg, Germany.
Flicek P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. .; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK. .; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. .
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Źródło :
BMC biology [BMC Biol] 2020 Sep 23; Vol. 18 (1), pp. 132. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Transcriptional activity and strain-specific history of mouse pseudogenes.
Autorzy :
Sisu C; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.; Department of Life Sciences, Brunel University London, London, UB8 3PH, UK.
Muir P; Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT, 06520, USA.; Systems Biology Institute, Yale University, West Haven, CT, 06516, USA.
Frankish A; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Fiddes I; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, 95064, USA.
Diekhans M; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, 95064, USA.
Thybert D; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.; Earlham Institute, Norwich Research Park, Norwich, NR4 7UH, UK.
Odom DT; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
Flicek P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
Keane TM; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Hubbard T; Department of Medical and Molecular Genetics, King's College London, London, SE1 9RT, UK.
Harrow J; Elexir, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA. .; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA. .; Systems Biology Institute, Yale University, West Haven, CT, 06516, USA. .; Department of Computer Science, Yale University, New Haven, CT, 06520, USA. .; Department of Statistics & Data Science, Yale University, New Haven, CT, 06520, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 29; Vol. 11 (1), pp. 3695. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
Pseudogenes/*genetics
Animals ; Conserved Sequence/genetics ; Evolution, Molecular ; Gene Ontology ; Genome ; Humans ; Mice, Inbred C57BL ; Molecular Sequence Annotation ; Species Specificity
Czasopismo naukowe
Tytuł :
Pervasive lesion segregation shapes cancer genome evolution.
Autorzy :
Aitken SJ; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Anderson CJ; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Connor F; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Pich O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sundaram V; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Feig C; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Rayner TF; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Lukk M; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Aitken S; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Luft J; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Kentepozidou E; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Arnedo-Pac C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Beentjes SV; School of Mathematics and Maxwell Institute, University of Edinburgh, Edinburgh, UK.
Davies SE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Drews RM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Ewing A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Kaiser VB; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Khamseh A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Higgs Centre for Theoretical Physics, University of Edinburgh, Edinburgh, UK.
López-Arribillaga E; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Redmond AM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Santoyo-Lopez J; Edinburgh Genomics (Clinical), The University of Edinburgh, Edinburgh, UK.
Sentís I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Talmane L; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Yates AD; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Semple CA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
López-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.
Flicek P; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Odom DT; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. Duncan.Odom@cruk.cam.ac.uk.; German Cancer Research Center (DKFZ), Division of Regulatory Genomics and Cancer Evolution, Heidelberg, Germany. Duncan.Odom@cruk.cam.ac.uk.
Taylor MS; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. .
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Corporate Authors :
Liver Cancer Evolution Consortium
Źródło :
Nature [Nature] 2020 Jul; Vol. 583 (7815), pp. 265-270. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Chromosome Segregation/*genetics
Genome/*genetics
Neoplasms/*genetics
Alleles ; Animals ; DNA Repair ; DNA Replication ; ErbB Receptors/metabolism ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Mice ; Mutation ; Neoplasms/pathology ; Selection, Genetic ; Signal Transduction ; Sister Chromatid Exchange ; Transcription, Genetic ; raf Kinases/metabolism ; ras Proteins/metabolism
Czasopismo naukowe
Tytuł :
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division.
Autorzy :
Stojic L; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. .; Centre for Cancer Cell and Molecular Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK. .
Lun ATL; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Genentech, Inc., South San Francisco, CA, USA.
Mascalchi P; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; DRVision Technologies, Bordeaux, France.
Ernst C; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Redmond AM; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK.
Mangei J; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Molecular Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Barr AR; Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.; MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Bousgouni V; Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
Bakal C; Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
Marioni JC; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; European Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.
Odom DT; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. duncan.odom@cruk.cam.ac.uk.; Division of Regulatory Genomics and Cancer Evolution, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. duncan.odom@cruk.cam.ac.uk.
Gergely F; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Apr 15; Vol. 11 (1), pp. 1851. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation.
Autorzy :
Karagianni P; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Herakleion, Crete, Greece; Biomedical Sciences Research Center Alexander Fleming, 16672 Vari, Greece.
Moulos P; Biomedical Sciences Research Center Alexander Fleming, 16672 Vari, Greece.
Schmidt D; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Odom DT; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Talianidis I; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Herakleion, Crete, Greece. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2020 Feb 04; Vol. 30 (5), pp. 1319-1328.e6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains.
Autorzy :
Kentepozidou E; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK.
Aitken SJ; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Department of Histopathology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK.
Feig C; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Stefflova K; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Ibarra-Soria X; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Odom DT; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Division Regulatory Genomics and Cancer Evolution, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Roller M; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK. .
Flicek P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK. .; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. .; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. .
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Źródło :
Genome biology [Genome Biol] 2020 Jan 07; Vol. 21 (1), pp. 5. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
CCCTC-Binding Factor/*genetics
CCCTC-Binding Factor/*metabolism
Chromatin/*metabolism
Mice/*genetics
Animals ; Chromatin Immunoprecipitation Sequencing ; Genome
Czasopismo naukowe
Tytuł :
Crisflash: open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation.
Autorzy :
Jacquin ALS; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK and.; Cetrale Nantes, 44321 Nantes, Cedex 3, France.
Odom DT; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK and.
Lukk M; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK and.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2019 Sep 01; Vol. 35 (17), pp. 3146-3147.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Clustered Regularly Interspaced Short Palindromic Repeats*
Genome*
Base Sequence ; CRISPR-Cas Systems ; Gene Editing ; RNA, Guide ; Software
Czasopismo naukowe
Tytuł :
IL-7-dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.
Autorzy :
Chen HC; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Eling N; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.
Martinez-Jimenez CP; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany.
O'Brien LM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Carbonaro V; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Marioni JC; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Odom DT; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Division of Signalling and Functional Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
de la Roche M; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
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Źródło :
EMBO reports 2019 Aug; Vol. 20 (8), pp. e47379. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Aging/*genetics
Carcinoma, Lewis Lung/*genetics
Interleukin-7/*genetics
Lymph Nodes/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*genetics
T-Lymphocyte Subsets/*immunology
Aging/immunology ; Animals ; Carcinoma, Lewis Lung/immunology ; Carcinoma, Lewis Lung/pathology ; Cell Differentiation ; Cell Lineage/genetics ; Cell Lineage/immunology ; Immunophenotyping ; Interleukin-17/genetics ; Interleukin-17/immunology ; Interleukin-7/immunology ; Lymph Nodes/pathology ; Mice ; Mice, Inbred C57BL ; Receptors, Antigen, T-Cell, gamma-delta/classification ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Signal Transduction ; T-Lymphocyte Subsets/classification ; T-Lymphocyte Subsets/pathology ; Tumor Burden/genetics ; Tumor Burden/immunology
Czasopismo naukowe

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