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    Wyświetlanie 1-3 z 3
    Tytuł:
    Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.
    Autorzy:
    van Huizen M; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Bloeme-Ter Horst JR; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    de Gruyter HLM; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Geurink PP; Department of Cell and Chemical Biology, Division of Chemical Biology and Drug Discovery, Leiden University Medical Centre, Leiden, The Netherlands.
    van der Heden van Noort GJ; Department of Cell and Chemical Biology, Division of Chemical Biology and Drug Discovery, Leiden University Medical Centre, Leiden, The Netherlands.
    Knaap RCM; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Nelemans T; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Ogando NS; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Leijs AA; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Urakova N; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Mark BL; Department of Microbiology, University of Manitoba, Winnipeg, Canada.
    Snijder EJ; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Myeni SK; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
    Kikkert M; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2024 Mar 25; Vol. 20 (3), pp. e1012100. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Coronavirus Papain-Like Proteases*/genetics
    COVID-19*
    Humans ; Animals ; Mice ; SARS-CoV-2/metabolism ; Immunity, Innate ; Papain/genetics ; Papain/metabolism ; Peptide Hydrolases/metabolism ; Virus Replication ; Polyproteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology.
    Autorzy:
    Thaler M; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Wang Y; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands, .
    van der Does AM; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
    Faiz A; Respiratory Bioinformatics and Molecular Biology (RBMB), School of Life Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.
    Ninaber DK; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
    Ogando NS; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Beckert H; Department of Pulmonary Medicine, University Medical Center Essen - Ruhrlandklinik, Essen, Germany.
    Taube C; Department of Pulmonary Medicine, University Medical Center Essen - Ruhrlandklinik, Essen, Germany.
    Salgado-Benvindo C; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Snijder EJ; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Bredenbeek PJ; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
    van Hemert MJ; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
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    Źródło:
    Journal of innate immunity [J Innate Immun] 2023; Vol. 15 (1), pp. 562-580. Date of Electronic Publication: 2023 Mar 25.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    COVID-19*
    Humans ; SARS-CoV-2 ; Respiratory System ; Epithelial Cells ; Biology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation.
    Autorzy:
    Dirmeier S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland.
    Dächert C; Research Group 'Dynamics of Early Viral Infection and the Innate Antiviral Response' (division F170), German Cancer Research Center, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
    van Hemert M; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Tas A; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    Ogando NS; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
    van Kuppeveld F; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
    Bartenschlager R; Department for Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.
    Kaderali L; University Medicine Greifswald, Institute of Bioinformatics, Greifswald, Germany.
    Binder M; Research Group 'Dynamics of Early Viral Infection and the Innate Antiviral Response' (division F170), German Cancer Research Center, Heidelberg, Germany.
    Beerenwinkel N; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland.
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    Źródło:
    PLoS computational biology [PLoS Comput Biol] 2020 Feb 10; Vol. 16 (2), pp. e1007587. Date of Electronic Publication: 2020 Feb 10 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Regulatory Networks*
    Models, Biological*
    Host Microbial Interactions/*genetics
    Viruses/*genetics
    Genes, Viral ; RNA Interference
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-3 z 3

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