Exposure-response relationships of etrolizumab in patients with moderately-to-severely active ulcerative colitis.
Autorzy:
Kassir N; Genentech, Inc., South San Francisco, California, USA. Zhu R; Genentech, Inc., South San Francisco, California, USA. Moein A; Genentech, Inc., South San Francisco, California, USA. Langenhorst J; Pharmetheus AB, Uppsala, Sweden. Ribbing J; Pharmetheus AB, Uppsala, Sweden. Zhang R; Genentech, Inc., South San Francisco, California, USA. Tang MT; Genentech, Inc., South San Francisco, California, USA. Oh YS; Genentech, Inc., South San Francisco, California, USA. Zhang W; Genentech, Inc., South San Francisco, California, USA.
Population pharmacokinetic analysis of etrolizumab in patients with moderately-to-severely active ulcerative colitis.
Autorzy:
Moein A; Genentech, Inc., South San Francisco, California, USA. Lu T; Genentech, Inc., South San Francisco, California, USA. Jönsson S; Pharmetheus AB, Uppsala, Sweden. Ribbing J; Pharmetheus AB, Uppsala, Sweden. Kassir N; Genentech, Inc., South San Francisco, California, USA. Zhang W; Genentech, Inc., South San Francisco, California, USA. Sperinde G; Genentech, Inc., South San Francisco, California, USA. Zhang R; Genentech, Inc., South San Francisco, California, USA. Tang M; Genentech, Inc., South San Francisco, California, USA. Oh YS; Genentech, Inc., South San Francisco, California, USA. Bruno R; Genentech/Roche, Marseille, France. Zhu R; Genentech, Inc., South San Francisco, California, USA.
Training and deploying a deep learning model for endoscopic severity grading in ulcerative colitis using multicenter clinical trial data.
Autorzy:
Gutierrez Becker B; Roche Pharma Research and Early Development Informatics, Roche Innovation Center Basel, Basel, Switzerland. Arcadu F; Roche Pharma Research and Early Development Informatics, Roche Innovation Center Basel, Basel, Switzerland. Thalhammer A; Roche Pharma Research and Early Development Informatics, Roche Innovation Center Basel, Basel, Switzerland. Gamez Serna C; Roche Pharma Research and Early Development Informatics, Roche Innovation Center Basel, Basel, Switzerland. Feehan O; Roche Pharma Research and Early Development Informatics, Roche Innovation Center Basel, Basel, Switzerland. Drawnel F; Roche Personalized Healthcare, Genentech, Inc., South San Francisco, CA, USA. Oh YS; Product Development, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA. Prunotto M; School of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland. Immunology, Infectious Disease & Ophthalmology, Roche, Basel, Switzerland.
Su1692 ANALYSIS OF VARIOUS CENTRAL ENDOSCOPY READING METHODOLOGIES IN THE BERGAMOT EXPLORATORY INDUCTION COHORT EVALUATING ETROLIZUMAB IN CROHN’S DISEASE
Shifting Demographics among Research Project Grant Awardees at the National Heart, Lung, and Blood Institute (NHLBI).
Autorzy:
Charette MF; Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America. Oh YS; Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America. Maric-Bilkan C; Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America. Scott LL; Statistical Analysis and Reporting Branch, Office of Planning, Analysis and Communication, Office of Extramural Research, National Institutes of Health, Bethesda, Maryland, United States of America. Wu CC; Statistical Analysis and Reporting Branch, Office of Planning, Analysis and Communication, Office of Extramural Research, National Institutes of Health, Bethesda, Maryland, United States of America. Eblen M; Office of Public Health Scientific Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America. Pearson K; Statistical Analysis and Reporting Branch, Office of Planning, Analysis and Communication, Office of Extramural Research, National Institutes of Health, Bethesda, Maryland, United States of America. Tolunay HE; Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America. Galis ZS; Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Dec 15; Vol. 11 (12), pp. e0168511. Date of Electronic Publication: 2016 Dec 15 (Print Publication: 2016).
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