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Tytuł:
Comparative effectiveness of tocilizumab vs standard care in patients with severe COVID-19-related pneumonia: a retrospective cohort study utilizing registry data as a synthetic control.
Autorzy:
Uemura Y; Biostatistics Section, Department of Data Science, Center for Clinical Sciences, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjyuku-ku, Tokyo, 162-8655, Japan. .
Ozaki R; Biometrics Department, Clinical Development Division, Chugai Pharmaceutical CO., LTD, Tokyo, Japan.
Shinozaki T; Department of Information and Computer Technology, Faculty of Engineering, Tokyo University of Science, Tokyo, Japan.
Ohtsu H; Clinical Pharmacology and Regulatory Sciences, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shimizu Y; Biostatistics Section, Department of Data Science, Center for Clinical Sciences, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjyuku-ku, Tokyo, 162-8655, Japan.
Izumi K; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Saito S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Matsunaga N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Ohmagari N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 Dec 04; Vol. 23 (1), pp. 849. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Humans ; SARS-CoV-2 ; Retrospective Studies ; Routinely Collected Health Data ; Treatment Outcome ; COVID-19 Drug Treatment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and Safety of Treatment with Plasma from COVID-19-Recovered Individuals.
Autorzy:
Terada M; Center for Clinical Sciences, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.; Disease Control and Prevention Center, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Saito S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Kutsuna S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Kinoshita-Iwamoto N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Togano T; Department of Hematology, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Hangaishi A; Department of Hematology, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Shiratori K; Laboratory Testing Department, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Takamatsu Y; Department of Refractory Viral Infections, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Maeda K; Division of Antiviral Therapy Joint Research Center for Human Retrovirus Infection, Kagoshima University, Sakuragaoka, Kagoshima 890-8544, Japan.
Ishizaka Y; Department of Intractable Diseases, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Ohtsu H; Faculty of Health Data Science, Juntendo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Satake M; Central Blood Institute, Japanese Red Cross, Tatsumi, Koto-ku, Tokyo 135-8521, Japan.
Mitsuya H; Department of Intractable Diseases, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Ohmagari N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
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Źródło:
Life (Basel, Switzerland) [Life (Basel)] 2023 Nov 09; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Allogeneic islet transplantation with monitoring of islet-specific cellular autoimmunity in a Japanese patient with type 1 diabetes: A case report.
Autorzy:
Chujo D; Pancreatic Islet Transplantation Project, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.; Department of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.; Center for Clinical Research, Toyama University Hospital, Toyama, Japan.
Kurokawa T; Department of Surgery, JCHO Tokyo Takanawa Hospital, Tokyo, Japan.
Kawabe A; Pancreatic Islet Transplantation Project, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Takahashi N; Department of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.
Inagaki F; Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Shinohara K; Pancreatic Islet Transplantation Project, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Hagiwara S; Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Edamoto Y; Department of Surgery, Secomedic Hospital, Chiba, Japan.
Ohmagari N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Hinoshita F; Nephrology, National Center for Global Health and Medicine, Tokyo, Japan.
Tajima T; Radiology, National Center for Global Health and Medicine, Tokyo, Japan.
Kajio H; Department of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.
Ohtsu H; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Takemura N; Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Matsumoto S; Pancreatic Islet Transplantation Project, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Shimoda M; Pancreatic Islet Transplantation Project, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
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Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2022 Apr; Vol. 13 (4), pp. 741-745. Date of Electronic Publication: 2021 Dec 17.
Typ publikacji:
Case Reports
MeSH Terms:
Diabetes Mellitus, Type 1*
Hematopoietic Stem Cell Transplantation*
Islets of Langerhans*
Islets of Langerhans Transplantation*
Autoimmunity ; Humans ; Japan ; Male ; Middle Aged
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Air pollution significantly associated with severe ocular allergic inflammatory diseases.
Autorzy:
Miyazaki D; Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, Yonago, Japan. .
Fukagawa K; Ryogoku Eye Clinic, Tokyo, Japan.
Fukushima A; Kochi University, Kochi, Japan.
Fujishima H; Tsurumi University School of Dental Medicine, Yokohama, Japan.
Uchio E; Fukuoka University, Fukuoka, Japan.
Ebihara N; Juntendo University, Tokyo, Japan.
Shoji J; Nihon University, Tokyo, Japan.
Takamura E; Tokyo Women's Medical University, Tokyo, Japan.
Namba K; Hokkaido University, Hokkaido, Japan.
Ohashi Y; Ehime University, Toon, Japan.
Okamoto S; Okamoto Eye Clinic, Matsuyama, Japan.
Satake Y; Tokyo Dental College, Tokyo, Japan.
Ohtsu H; Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Shimizu Y; Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, Yonago, Japan.
Inoue Y; Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, Yonago, Japan.
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Źródło:
Scientific reports [Sci Rep] 2019 Dec 03; Vol. 9 (1), pp. 18205. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Air Pollutants/*immunology
Air Pollution/*adverse effects
Allergens/*immunology
Conjunctivitis, Allergic/*epidemiology
Keratoconjunctivitis/*epidemiology
Adolescent ; Adult ; Air Pollution/statistics & numerical data ; Conjunctivitis, Allergic/immunology ; Cross-Sectional Studies ; Environmental Monitoring/statistics & numerical data ; Female ; Humans ; Japan/epidemiology ; Keratoconjunctivitis/immunology ; Male ; Middle Aged ; Nitrogen Dioxide/immunology ; Particulate Matter/immunology ; Prevalence ; Risk Factors ; Seasons ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lipopolysaccharide-induced expansion of histidine decarboxylase-expressing Ly6G myeloid cells identified by exploiting histidine decarboxylase BAC-GFP transgenic mice.
Autorzy:
Takai J; Division of Medical Biochemistry, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Ohtsu H; Department of Quantum Science and Energy Engineering, Tohoku University Graduate School of Engineering, Sendai, Japan.
Sato A; Department of Quantum Science and Energy Engineering, Tohoku University Graduate School of Engineering, Sendai, Japan.
Uemura S; Division of Medical Biochemistry, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Fujimura T; Laboratory of Bioanalytical Chemistry, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Yamamoto M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.; Tohoku Medical Mega-Bank Organization, Tohoku University, Sendai, Japan.
Moriguchi T; Division of Medical Biochemistry, Tohoku Medical and Pharmaceutical University, Sendai, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2019 Oct 30; Vol. 9 (1), pp. 15603. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomes, Artificial, Bacterial/*genetics
Gene Expression Regulation, Enzymologic/*drug effects
Green Fluorescent Proteins/*genetics
Histidine Decarboxylase/*metabolism
Lipopolysaccharides/*pharmacology
Myeloid Cells/*drug effects
Myeloid Cells/*metabolism
Animals ; Hematopoiesis/drug effects ; Histamine/biosynthesis ; Lung/cytology ; Lung/drug effects ; Lung/metabolism ; Mice ; Mice, Transgenic ; Myeloid Cells/cytology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Screening Biomarker as an Alternative to Endoscopy for the Detection of Early Gastric Cancer: The Combination of Serum Trefoil Factor Family 3 and Pepsinogen.
Autorzy:
Lee HS; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.
Jeon SW; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.
Nomura S; Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Seto Y; Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Kwon YH; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.
Nam SY; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.
Ishibashi Y; Department of Breast and Endocrine Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Ohtsu H; Department of Clinical Trial Data Management, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Ohmoto Y; Otsuka Pharmaceutical Co. Ltd., Tokyo, Japan.
Yang HM; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Republic of Korea.
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Źródło:
Gastroenterology research and practice [Gastroenterol Res Pract] 2018 May 09; Vol. 2018, pp. 1024074. Date of Electronic Publication: 2018 May 09 (Print Publication: 2018).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Induced histamine regulates Ni elution from an implanted Ni wire in mice by downregulating neutrophil migration.
Autorzy:
Kishimoto Y; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Asakawa S; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Sato T; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Takano T; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Nakajyo T; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Mizuno N; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Segawa R; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Yoshikawa T; Department of Pharmacology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Hiratsuka M; Department of Pharmacology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Yanai K; Department of Pharmacology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Ohtsu H; Department of Quantum Science and Energy Engineering, Graduate School of Engineering, Tohoku University, Sendai, Japan.
Hirasawa N; Laboratory of Pharmacotherapy of Life-style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
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Źródło:
Experimental dermatology [Exp Dermatol] 2017 Oct; Vol. 26 (10), pp. 868-874. Date of Electronic Publication: 2017 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement*
Histamine/*metabolism
Inflammation/*metabolism
Neutrophils/*physiology
Nickel/*metabolism
RNA, Messenger/*metabolism
Animals ; Cells, Cultured ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Chemokine CXCL2/genetics ; Chemokine CXCL2/metabolism ; Down-Regulation ; Gene Expression/drug effects ; Histamine/pharmacology ; Histidine Decarboxylase/genetics ; Histidine Decarboxylase/metabolism ; Inflammation/etiology ; Inflammation/genetics ; Macrophages/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nickel/adverse effects ; Nickel/pharmacology ; Prostheses and Implants ; Receptors, Histamine H2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease.
Autorzy:
Takuse Y; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Watanabe M; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Inoue N; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.; b Laboratory for Clinical Investigation , Osaka University Hospital , Suita , Osaka , Japan.
Ozaki R; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Ohtsu H; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Saeki M; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Katsumata Y; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
Hidaka Y; b Laboratory for Clinical Investigation , Osaka University Hospital , Suita , Osaka , Japan.
Iwatani Y; a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.
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Źródło:
Immunological investigations [Immunol Invest] 2017 Aug; Vol. 46 (6), pp. 590-602. Date of Electronic Publication: 2017 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Graves Disease*/genetics
Graves Disease*/immunology
Hashimoto Disease*/genetics
Hashimoto Disease*/immunology
Interleukin-10/*immunology
Leukocytes, Mononuclear/*immunology
MicroRNAs/*immunology
Adult ; Female ; Gene Frequency ; Genotype ; Humans ; Male ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Deficiency of histidine decarboxylase attenuates peripheral nerve fibre elongation into the epidermis in surfactant-treated mouse skin.
Autorzy:
Inami Y; Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.; Department of Quantum Science and Energy Engineering, Graduate School of Engineering, Tohoku University, Miyagi, Japan.; Fundamental Research Laboratory, Hoyu Co., Ltd., Aichi, Japan.
Sato A; Department of Quantum Science and Energy Engineering, Graduate School of Engineering, Tohoku University, Miyagi, Japan.
Ohtsu H; Department of Quantum Science and Energy Engineering, Graduate School of Engineering, Tohoku University, Miyagi, Japan.
Mano Y; Fundamental Research Laboratory, Hoyu Co., Ltd., Aichi, Japan.
Sasaki A; Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Kuraishi Y; Research Administration Division, Tokyo Medical and Dental University, Tokyo, Japan.
Andoh T; Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
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Źródło:
Experimental dermatology [Exp Dermatol] 2017 May; Vol. 26 (5), pp. 441-443.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Dermatitis, Contact/*etiology
Epidermis/*innervation
Histamine/*metabolism
Nerve Fibers/*drug effects
Sodium Dodecyl Sulfate/*adverse effects
Animals ; Epidermis/drug effects ; Female ; Histidine Decarboxylase/genetics ; Male ; Mice, Inbred ICR ; Mice, Knockout
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis.
Autorzy:
Hattori M; Department of Anesthesiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Yamazaki M; Department of Anesthesiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Ohashi W; Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Tanaka S; Department of Immunobiology, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Hattori K; Department of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, Tokyo, Japan.
Todoroki K; Department of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Fujimori T; Department of Anesthesiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Ohtsu H; Department of Applied Quantum Medical Engineering, School of Engineering, Tohoku University, Sendai, Japan.
Matsuda N; Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hattori Y; Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. .
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Źródło:
Intensive care medicine experimental [Intensive Care Med Exp] 2016 Dec; Vol. 4 (1), pp. 36. Date of Electronic Publication: 2016 Nov 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A critical time window for the analgesic effect of central histamine in the partial sciatic ligation model of neuropathic pain.
Autorzy:
Yu J; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.; College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Tang YY; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Wang RR; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Lou GD; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Hu TT; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Hou WW; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Yue JX; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Ohtsu H; Department of Engineering, School of Medicine, Tohoku University, Aoba-ku, Sendai, 980-8775, Japan.
Shi LY; Department of Basic Medical Science, Hangzhou Normal University, Hangzhou, 311121, Zhejiang, China.
Zhang SH; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China. .
Chen Z; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China. .; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2016 Jun 24; Vol. 13 (1), pp. 163. Date of Electronic Publication: 2016 Jun 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sciatic Neuropathy*/drug therapy
Sciatic Neuropathy*/metabolism
Sciatic Neuropathy*/pathology
Analgesics/*therapeutic use
Central Nervous System/*metabolism
Histidine/*therapeutic use
Analgesics/pharmacology ; Animals ; Central Nervous System/drug effects ; Cimetidine/pharmacology ; Disease Models, Animal ; Drug Administration Routes ; Histamine H1 Antagonists/pharmacology ; Histamine H2 Antagonists/pharmacology ; Histidine/pharmacology ; Histidine Decarboxylase/deficiency ; Histidine Decarboxylase/genetics ; Hyperalgesia/drug therapy ; Hyperalgesia/etiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pain Threshold/drug effects ; Pyrilamine/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Interleukin-1/deficiency ; Receptors, Interleukin-1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mast cell histamine-mediated transient inflammation following exposure to nickel promotes nickel allergy in mice.
Autorzy:
Kinbara M; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.; Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Bando K; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.; Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Shiraishi D; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Kuroishi T; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Nagai Y; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Ohtsu H; Department of Applied Quantum Medical Engineering, School of Engineering, Tohoku University, Sendai, Japan.
Takano-Yamamoto T; Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Sugawara S; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Endo Y; Department of Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
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Źródło:
Experimental dermatology [Exp Dermatol] 2016 Jun; Vol. 25 (6), pp. 466-71. Date of Electronic Publication: 2016 May 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dermatitis, Allergic Contact/*immunology
Histamine/*metabolism
Mast Cells/*physiology
Nickel/*immunology
Animals ; Cromolyn Sodium ; Dermatitis, Allergic Contact/metabolism ; Female ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
How effective is an in-hospital heart failure self-care program in a Japanese setting? Lessons from a randomized controlled pilot study.
Autorzy:
Kato NP; Department of Therapeutic Strategy for Heart Failure, The University of Tokyo Graduate School of Medicine, Tokyo, Japan; Department of Social and Welfare Studies, Faculty of Health Sciences, Linköping University, Linköping, Sweden; JSPS Postdoctoral Fellow for Research Abroad, Tokyo, Japan.
Kinugawa K; Department of Therapeutic Strategy for Heart Failure, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Sano M; Department of Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Kogure A; Department of Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Sakuragi F; Department of Pharmacy, The University of Tokyo Hospital, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Kobukata K; Department of Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Ohtsu H; Department of Clinical Data Management, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Wakita S; Department of Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Jaarsma T; Department of Social and Welfare Studies, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Kazuma K; Department of Adult Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
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Źródło:
Patient preference and adherence [Patient Prefer Adherence] 2016 Feb 18; Vol. 10, pp. 171-81. Date of Electronic Publication: 2016 Feb 18 (Print Publication: 2016).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin Neuron Deficiency.
Autorzy:
Bastianini S; PRISM Laboratory, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Silvani A; PRISM Laboratory, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Berteotti C; PRISM Laboratory, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Lo Martire V; PRISM Laboratory, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Cohen G; Department of Women & Child Health, Karolinska Institutet, Stockholm, Sweden.
Ohtsu H; Applied Quantum Medical Engineering, Graduate School of Engineering, Tohoku University, Sendai, Japan.
Lin JS; Physiologie intégrée du système d'éveil, Centre de recherche en neurosciences de Lyon, INSERM U1028-CNRS UMR 5292 Faculté de Médecine, Université Claude Bernard, Lyon, France.
Zoccoli G; PRISM Laboratory, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
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Źródło:
PloS one [PLoS One] 2015 Oct 16; Vol. 10 (10), pp. e0140520. Date of Electronic Publication: 2015 Oct 16 (Print Publication: 2015).
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Signal Transduction*
Histamine/*metabolism
Narcolepsy/*metabolism
Narcolepsy/*pathology
Neurons/*metabolism
Orexins/*deficiency
Animals ; Body Weight ; Cardiovascular System/physiopathology ; Cataplexy/metabolism ; Cataplexy/pathology ; Cataplexy/physiopathology ; Energy Intake ; Female ; Gene Knockout Techniques ; Histidine Decarboxylase/deficiency ; Histidine Decarboxylase/genetics ; Male ; Mice ; Respiration ; Sleep ; Wakefulness
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation.
Autorzy:
Zhao YY; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Yuan Y
Chen Y
Jiang L
Liao RJ
Wang L
Zhang XN
Ohtsu H
Hu WW
Chen Z
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2015 May; Vol. 21 (5), pp. 454-62. Date of Electronic Publication: 2015 Jan 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cicatrix/*prevention & control
Histamine/*pharmacology
Locomotion/*drug effects
Neuroprotective Agents/*pharmacology
Recovery of Function/*drug effects
Spinal Cord Injuries/*drug therapy
Animals ; Astrocytes/drug effects ; Astrocytes/pathology ; Astrocytes/physiology ; Cicatrix/pathology ; Cicatrix/physiopathology ; Disease Models, Animal ; Female ; Histamine Agonists/pharmacology ; Histidine Decarboxylase/genetics ; Histidine Decarboxylase/metabolism ; Locomotion/physiology ; Mice, Inbred C57BL ; Mice, Knockout ; Rats, Sprague-Dawley ; Receptors, Histamine H1/metabolism ; Receptors, Histamine H2/metabolism ; Recovery of Function/physiology ; Spinal Cord/drug effects ; Spinal Cord/pathology ; Spinal Cord/physiopathology ; Spinal Cord Injuries/pathology ; Spinal Cord Injuries/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of histamine in the retina: studies on the Hdc knockout mouse.
Autorzy:
Greferath U; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
Vessey KA; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
Jobling AI; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
Mills SA; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
Bui BV; Department of Optometry and Vision Sciences, The University of Melbourne, Parkville, Victoria, Australia.
He Z; Department of Optometry and Vision Sciences, The University of Melbourne, Parkville, Victoria, Australia.
Nag N; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
Ohtsu H; Department of Engineering, Medical School of Tohoku University, Sendai, Japan.
Fletcher EL; Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Victoria, Australia.
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Źródło:
PloS one [PLoS One] 2014 Dec 29; Vol. 9 (12), pp. e116025. Date of Electronic Publication: 2014 Dec 29 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histamine/*metabolism
Histidine Decarboxylase/*deficiency
Retina/*metabolism
Animals ; Cell Count ; Histidine Decarboxylase/metabolism ; Mammals/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/metabolism ; Microglia/pathology ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Regional Blood Flow ; Retina/pathology ; Retinal Cone Photoreceptor Cells/metabolism ; Retinal Rod Photoreceptor Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Roles of histamine on the expression of aldehyde dehydrogenase 1 in endometrioid adenocarcinoma cell line.
Autorzy:
Wang Y; Department of Pathology, Osaka University Graduate School of Medicine, Yamada-oka 2-2, Suita, 565-0871, Japan.
Jiang Y
Ikeda J
Tian T
Sato A
Ohtsu H
Morii E
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Źródło:
Cancer medicine [Cancer Med] 2014 Oct; Vol. 3 (5), pp. 1126-35. Date of Electronic Publication: 2014 Jul 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Endometrioid/*metabolism
Histamine/*pharmacology
Isoenzymes/*metabolism
Retinal Dehydrogenase/*metabolism
Aldehyde Dehydrogenase 1 Family ; Antineoplastic Agents/pharmacology ; Biomarkers, Tumor ; Carcinoma, Endometrioid/genetics ; Carcinoma, Endometrioid/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm ; Gene Expression Regulation, Neoplastic/drug effects ; Histamine Agonists/pharmacology ; Histamine Antagonists/pharmacology ; Humans ; Isoenzymes/genetics ; Receptors, Histamine/genetics ; Receptors, Histamine/metabolism ; Retinal Dehydrogenase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Roles played by histamine in strenuous or prolonged masseter muscle activity in mice.
Autorzy:
Yoneda H; Division of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku University, Sendai, Japan; Division of Advanced Prosthetic Dentistry, Graduate School of Dentistry, Tohoku University, Sendai, Japan.
Niijima-Yaoita F
Tsuchiya M
Kumamoto H
Watanbe M
Ohtsu H
Yanai K
Tadano T
Sasaki K
Sugawara S
Endo Y
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2013 Dec; Vol. 40 (12), pp. 848-55.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histamine/*physiology
Histamine H1 Antagonists/*pharmacology
Masseter Muscle/*drug effects
Motor Activity/*drug effects
Animals ; Bruxism/metabolism ; Bruxism/prevention & control ; Histamine/metabolism ; Histamine H1 Antagonists/therapeutic use ; Histidine Decarboxylase/genetics ; Histidine Decarboxylase/metabolism ; Male ; Masseter Muscle/blood supply ; Masseter Muscle/metabolism ; Mast Cells/drug effects ; Mast Cells/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Motor Activity/physiology ; Receptors, Histamine H1/genetics ; Receptors, Histamine H1/metabolism ; Restraint, Physical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Histamine modulation of acute nociception involves regulation of Nav 1.8 in primary afferent neurons in mice.
Autorzy:
Yu J; Department of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, College of Pharmaceutical Sciences, School of Medicine, Zhejiang University, Hangzhou, China.
Fang Q
Lou GD
Shou WT
Yue JX
Tang YY
Hou WW
Xu TL
Ohtsu H
Zhang SH
Chen Z
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2013 Sep; Vol. 19 (9), pp. 649-58. Date of Electronic Publication: 2013 Jun 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histamine/*physiology
NAV1.8 Voltage-Gated Sodium Channel/*physiology
Neurons, Afferent/*physiology
Nociception/*physiology
Action Potentials ; Acute Disease ; Animals ; Ganglia, Spinal/physiology ; Histidine Decarboxylase/physiology ; Methylhistidines/pharmacology ; Mice ; Tetrodotoxin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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