- Tytuł:
-
Mechanism of metal-mediated DNA damage and
apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells. - Autorzy:
- Źródło:
- Free radical research [Free Radic Res] 2008 Jul; Vol. 42 (7), pp. 651-60.
- Typ publikacji:
-
Journal Article; Research Support, Non-U.
S . Gov't - MeSH Terms:
-
DNA Damage*
Apoptosis /*drug effectsCopper /*metabolism
Iron/*metabolism
Neuroblastoma/*pathology
Neurons/*drug effects
Oxidative Stress/*drug effects
Oxidopamine/*toxicity
8-Hydroxy-2'-Deoxyguanosine ; Benzoquinones/metabolism ; Biomarkers/metabolism ; Cell Line, Tumor ; Chelating Agents/pharmacology ; DNA Fragmentation ; Deoxyguanosine/analogs & derivatives ; Deoxyguanosine/metabolism ; Dose-Response Relationship, Drug ; Free Radical Scavengers/pharmacology ; Humans ; Hydrogen Peroxide/metabolism ; Iron Chelating Agents/pharmacology ; Neuroblastoma/genetics ; Neuroblastoma/metabolism ; Neurons/metabolism ; Neurons/pathology ; Oxidation-Reduction ; Time Factors
Czasopismo naukowe