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Tytuł :
A mechanism for matrikine regulation in acute inflammatory lung injury.
Autorzy :
Robison SW; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Li J; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Birmingham VA Medical Center, Birmingham, Alabama, USA.
Viera L; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Blackburn JP; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Patel RP; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Pathology, Division of Molecular and Cellular Pathology, and.; Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Blalock JE; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Gregory Fleming James Cystic Fibrosis Research Center, Birmingham, Alabama, USA.; Lung Health Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Gaggar A; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Birmingham VA Medical Center, Birmingham, Alabama, USA.; Gregory Fleming James Cystic Fibrosis Research Center, Birmingham, Alabama, USA.; Lung Health Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Xu X; Department of Medicine, Division of Pulmonology, Allergy and Critical Care Medicine, and.; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Birmingham VA Medical Center, Birmingham, Alabama, USA.; Gregory Fleming James Cystic Fibrosis Research Center, Birmingham, Alabama, USA.; Lung Health Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
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Źródło :
JCI insight [JCI Insight] 2021 Apr 08; Vol. 6 (7). Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
COVID-19*/immunology
COVID-19*/metabolism
Oligopeptides*/immunology
Oligopeptides*/pharmacology
Symporters*/antagonists & inhibitors
Symporters*/metabolism
Acute Lung Injury/*immunology
Cefadroxil/*pharmacology
Inflammation/*metabolism
Proline/*analogs & derivatives
Animals ; Anti-Bacterial Agents/pharmacology ; Biological Transport, Active/immunology ; Cells, Cultured ; Chemotactic Factors/immunology ; Chemotactic Factors/pharmacology ; Chemotaxis, Leukocyte/immunology ; Disease Models, Animal ; Extracellular Matrix ; Extracellular Matrix Proteins/metabolism ; Humans ; Mice ; Proline/immunology ; Proline/pharmacology
Czasopismo naukowe
Tytuł :
Docetaxel-Induced Interstitial Pneumonitis Detected on 68Ga-PSMA PET/CT.
Autorzy :
Kumar S; From the Departments of Nuclear Medicine and PET.
Singh H; From the Departments of Nuclear Medicine and PET.
Das CK; Medical Oncology, Regional Cancer Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Kumar R; From the Departments of Nuclear Medicine and PET.
Mittal BR; From the Departments of Nuclear Medicine and PET.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 May 01; Vol. 46 (5), pp. e268-e269.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Oligopeptides*
Positron Emission Tomography Computed Tomography*
Docetaxel/*adverse effects
Edetic Acid/*analogs & derivatives
Lung Diseases, Interstitial/*chemically induced
Lung Diseases, Interstitial/*diagnostic imaging
Aged ; Docetaxel/therapeutic use ; Humans ; Male ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Renal failure among multiple myeloma patients utilizing carfilzomib and associated factors in the "real world".
Autorzy :
Mian HS; Department of Oncology, McMaster University, 699 Concession St., Hamilton, ON, L8V 5C2, Canada. .
Fiala MA; Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.; College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO, USA.
Sanchez L; Department of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Vij R; Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Wildes TM; Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.
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Źródło :
Annals of hematology [Ann Hematol] 2021 May; Vol. 100 (5), pp. 1261-1266. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*adverse effects
Multiple Myeloma/*drug therapy
Oligopeptides/*adverse effects
Proteasome Inhibitors/*adverse effects
Renal Insufficiency/*chemically induced
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Oligopeptides/therapeutic use ; Proportional Hazards Models ; Proteasome Inhibitors/therapeutic use ; Renal Insufficiency/etiology ; Risk Factors
Czasopismo naukowe
Tytuł :
Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography.
Autorzy :
Kneller DW; Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.
Phillips G; Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.
Weiss KL; Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.
Zhang Q; Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.
Coates L; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.; Second Target Station, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.
Kovalevsky A; Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, D.C. 20585, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Apr 22; Vol. 64 (8), pp. 4991-5000. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus 3C Proteases/*antagonists & inhibitors
Coronavirus 3C Proteases/*chemistry
Oligopeptides/*chemistry
Binding Sites ; Coronavirus 3C Proteases/metabolism ; Crystallography/methods ; Crystallography, X-Ray ; Cysteine Proteinase Inhibitors/chemistry ; Cysteine Proteinase Inhibitors/metabolism ; Models, Molecular ; Neutrons ; Oligopeptides/metabolism ; Protein Conformation ; Protons
Czasopismo naukowe
Tytuł :
Synthesis, characterization, and targeted chemotherapy of SCT200-linker-monomethyl auristatin E conjugates.
Autorzy :
Hu X; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China; National Institutes for Food and Drug Control, Beijing, 102629, China.
Jiang H; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Bai W; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Liu X; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Miao Q; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Wang L; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Jin J; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Cui A; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Liu R; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: .
Li Z; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Apr 15; Vol. 216, pp. 113297. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal/*chemistry
Antineoplastic Agents/*chemical synthesis
Immunoconjugates/*chemistry
Oligopeptides/*chemistry
Animals ; Antineoplastic Agents/blood ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Cathepsin B/metabolism ; Cell Line, Tumor ; Drug Liberation ; Drug Stability ; ErbB Receptors/genetics ; ErbB Receptors/immunology ; ErbB Receptors/metabolism ; Female ; Gene Expression Regulation/drug effects ; Humans ; Immunoconjugates/blood ; Immunoconjugates/pharmacology ; Immunoconjugates/therapeutic use ; Mice ; Mice, Nude ; Neoplasms/drug therapy ; Neoplasms/pathology ; Oligopeptides/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Impact of total variation regularized expectation maximization reconstruction on the image quality of Ga-PSMA PET: a phantom and patient study.
Autorzy :
Yang FJ; Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Ai SY; Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Wu R; United Imaging Healthcare, Shanghai 201870, China.
Lv Y; United Imaging Healthcare, Shanghai 201870, China.
Xie HF; United Imaging Healthcare, Shanghai 201870, China.
Dong Y; United Imaging Healthcare, Shanghai 201870, China.
Meng QL; Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Wang F; Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
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Źródło :
The British journal of radiology [Br J Radiol] 2021 Apr 01; Vol. 94 (1120), pp. 20201356. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Oligopeptides*
Edetic Acid/*analogs & derivatives
Image Interpretation, Computer-Assisted/*methods
Positron Emission Tomography Computed Tomography/*methods
Prostatic Neoplasms/*diagnostic imaging
Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Prostate/diagnostic imaging ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
68Ga-Prostate-Specific Membrane Antigen PET/CT in Sinonasal Glomangiopericytoma-Exploring Theranostic Avenues!
Autorzy :
Sakthivel P; From the Departments of Otorhinolaryngology & Head and Neck Surgery.
Kumar A; Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Arunraj ST; Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Thakur K; From the Departments of Otorhinolaryngology & Head and Neck Surgery.
Jaiswal AS; From the Departments of Otorhinolaryngology & Head and Neck Surgery.
Singh CA; From the Departments of Otorhinolaryngology & Head and Neck Surgery.
Kumar R; Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. 340-341.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Oligopeptides*
Positron Emission Tomography Computed Tomography*
Edetic Acid/*analogs & derivatives
Vascular Neoplasms/*diagnostic imaging
Vascular Neoplasms/*therapy
Adult ; Humans ; Male ; Precision Medicine
Czasopismo naukowe
Tytuł :
Oligodendroglioma in 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT.
Autorzy :
Pernthaler B; From the Divisions of Nuclear Medicine.
Nazerani Hooshmand T; From the Divisions of Nuclear Medicine.
Igrec J; General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Kvaternik H; From the Divisions of Nuclear Medicine.
Aigner RM; From the Divisions of Nuclear Medicine.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. e231-e232.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Carboxylic Acids*
Cyclobutanes*
Oligopeptides*
Positron Emission Tomography Computed Tomography*
Edetic Acid/*analogs & derivatives
Oligodendroglioma/*diagnostic imaging
Aged, 80 and over ; Humans ; Male ; Oligodendroglioma/pathology ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Recurrence
Czasopismo naukowe
Tytuł :
Is 68Ga-Prostate-Specific Membrane Antigen PET/CT Superior than 18F-FDG PET/CT for Evaluation of Metastatic Osteosarcoma?
Autorzy :
Can C; From the Department of Nuclear Medicine, Gazi Yaşargil Training and Research Hospital, University of Health Sciences, Diyarbakir, Turkey.
Gündoğan C
Kömek H
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. e233-e235.
Typ publikacji :
Case Reports; Comparative Study; Journal Article
MeSH Terms :
Fluorodeoxyglucose F18*
Oligopeptides*
Bone Neoplasms/*diagnostic imaging
Bone Neoplasms/*pathology
Edetic Acid/*analogs & derivatives
Osteosarcoma/*diagnostic imaging
Osteosarcoma/*pathology
Positron Emission Tomography Computed Tomography/*methods
Aged ; Humans ; Male ; Neoplasm Metastasis ; Sternum/diagnostic imaging
Czasopismo naukowe
Tytuł :
Metastatic Poorly Differentiated Thyroid Cancer With Heterogeneous Distribution of 18F-FDG, 68Ga-DOTATATE, and 68Ga-PSMA on PET/CT.
Autorzy :
Civan C; From the Department of Nuclear Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Isik EG
Simsek DH
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. e212-e213.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Fluorodeoxyglucose F18*
Oligopeptides*
Organometallic Compounds*
Positron Emission Tomography Computed Tomography*
Edetic Acid/*analogs & derivatives
Thyroid Neoplasms/*diagnostic imaging
Thyroid Neoplasms/*pathology
Humans ; Male ; Middle Aged ; Neoplasm Metastasis
Czasopismo naukowe
Tytuł :
Rapidly Evolving Diffuse Omental Carcinomatosis of Prostate Cancer in 68Ga-PSMA PET/CT.
Autorzy :
Hoberück S; From the Departments of Nuclear Medicine.
Sommer U; Pathology.
Grey A; Radiology.
Hölscher T
Baretton GB; Pathology.
Kotzerke J; From the Departments of Nuclear Medicine.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. e216-e217.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Oligopeptides*
Positron Emission Tomography Computed Tomography*
Edetic Acid/*analogs & derivatives
Omentum/*diagnostic imaging
Peritoneal Neoplasms/*diagnostic imaging
Peritoneal Neoplasms/*secondary
Prostatic Neoplasms/*pathology
Aged, 80 and over ; Humans ; Male ; Omentum/pathology
Czasopismo naukowe
Tytuł :
Natural bioeffective cyclooligopeptides from plant seeds of Annona genus.
Autorzy :
Dahiya R; School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago, West Indies. Electronic address: .
Dahiya S; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, 00936, USA. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Mar 15; Vol. 214, pp. 113221. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Annona/*chemistry
Anti-Inflammatory Agents/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Biological Products/*pharmacology
Oligopeptides/*pharmacology
Plant Extracts/*pharmacology
Anti-Inflammatory Agents/chemistry ; Antineoplastic Agents, Phytogenic/chemistry ; Biological Products/chemistry ; Humans ; Molecular Structure ; Oligopeptides/chemistry ; Plant Extracts/chemistry ; Seeds/chemistry
Czasopismo naukowe
Tytuł :
A Novel Anti-Inflammatory d-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model.
Autorzy :
Post J; Institute of Biological Information Processing, Structural Biochemistry, IBI-7, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Kogel V; Institute of Biological Information Processing, Structural Biochemistry, IBI-7, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Schaffrath A; Institute of Biological Information Processing, Structural Biochemistry, IBI-7, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Lohmann P; Institute of Neuroscience and Medicine 4, INM-4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Shah NJ; Institute of Neuroscience and Medicine 4, INM-4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.; Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.; JARA-Brain-Translational Medicine, 52074 Aachen, Germany.; Department of Neurology, RWTH Aachen University, 52062 Aachen, Germany.
Langen KJ; Institute of Neuroscience and Medicine 4, INM-4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.; Department of Nuclear Medicine, RWTH Aachen University, 52062 Aachen, Germany.
Willbold D; Institute of Biological Information Processing, Structural Biochemistry, IBI-7, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.; Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.
Willuweit A; Institute of Neuroscience and Medicine 4, INM-4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Kutzsche J; Institute of Biological Information Processing, Structural Biochemistry, IBI-7, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Mar 13; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Amyotrophic Lateral Sclerosis/*drug therapy
Anti-Inflammatory Agents/*therapeutic use
Oligopeptides/*therapeutic use
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/physiopathology ; Animals ; Anti-Inflammatory Agents/chemistry ; Brain Stem/drug effects ; Brain Stem/pathology ; Disease Models, Animal ; Disease Progression ; Female ; Humans ; Mice ; Mice, Transgenic ; Motor Neurons/drug effects ; Motor Neurons/pathology ; Motor Skills/drug effects ; Motor Skills/physiology ; Mutant Proteins/genetics ; Neurodegenerative Diseases/drug therapy ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/physiopathology ; Oligopeptides/chemistry ; Phenotype ; Spinal Cord/drug effects ; Spinal Cord/pathology ; Superoxide Dismutase/genetics ; Superoxide Dismutase-1/genetics
Czasopismo naukowe
Tytuł :
Pyoverdines Are Essential for the Antibacterial Activity of Pseudomonas chlororaphis YL-1 under Low-Iron Conditions.
Autorzy :
Liu Y; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.; Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology, Mississippi State University, Mississippi State, Mississippi, USA.
Dai C; College of Life Sciences, Nanjing Agricultural University, Nanjing, China.
Zhou Y; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Qiao J; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Tang B; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Yu W; College of Life Sciences, Nanjing Agricultural University, Nanjing, China.
Zhang R; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Liu Y; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China .
Lu SE; Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology, Mississippi State University, Mississippi State, Mississippi, USA .
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Źródło :
Applied and environmental microbiology [Appl Environ Microbiol] 2021 Mar 11; Vol. 87 (7). Date of Electronic Publication: 2021 Mar 11 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Iron/*metabolism
Oligopeptides/*pharmacology
Pseudomonas chlororaphis/*metabolism
Anti-Bacterial Agents/chemistry ; Chromatography, Liquid ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Oligopeptides/chemistry ; Pseudomonas chlororaphis/chemistry ; Pseudomonas chlororaphis/genetics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4 Diffuse Large B-Cell Lymphoma Cells.
Autorzy :
Falgàs A; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.
Pallarès V; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.
Unzueta U; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.
Núñez Y; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.
Sierra J; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.
Gallardo A; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.
Alba-Castellón L; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.
Mangues MA; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.; Department of Pharmacy, Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.
Álamo P; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.
Villaverde A; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.
Vázquez E; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.
Mangues R; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.
Casanova I; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, 08916, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Madrid, 28029, Spain.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Mar 05; Vol. 16, pp. 1869-1888. Date of Electronic Publication: 2021 Mar 05 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Lymphoma, Large B-Cell, Diffuse/*drug therapy
Lymphoma, Large B-Cell, Diffuse/*pathology
Nanoconjugates/*therapeutic use
Oligopeptides/*therapeutic use
Receptors, CXCR4/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Death/drug effects ; Cell Line, Tumor ; Disease Models, Animal ; Endocytosis/drug effects ; Female ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/pathology ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lysosomes/drug effects ; Lysosomes/metabolism ; Mice, Inbred NOD ; Mice, SCID ; Oligopeptides/pharmacology ; Signal Transduction/drug effects ; Subcutaneous Tissue/drug effects ; Subcutaneous Tissue/pathology ; Tissue Distribution/drug effects
Czasopismo naukowe
Tytuł :
A computational drug repurposing approach in identifying the cephalosporin antibiotic and anti-hepatitis C drug derivatives for COVID-19 treatment.
Autorzy :
Kumar R; Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh, 173 234, India. Electronic address: .
Kumar V; Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), 501 Jinju-daero, Jinju, 52828, Republic of Korea.
Lee KW; Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), 501 Jinju-daero, Jinju, 52828, Republic of Korea. Electronic address: .
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Źródło :
Computers in biology and medicine [Comput Biol Med] 2021 Mar; Vol. 130, pp. 104186. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus 3C Proteases*/antagonists & inhibitors
Coronavirus 3C Proteases*/chemistry
Drug Repositioning*
Molecular Dynamics Simulation*
SARS-CoV-2*/chemistry
SARS-CoV-2*/enzymology
COVID-19/*drug therapy
COVID-19/*enzymology
Cephalosporins/*chemistry
Hepacivirus/*enzymology
Hepatitis C/*drug therapy
Oligopeptides/*chemistry
Cephalosporins/therapeutic use ; Hepatitis C/enzymology ; Humans ; Oligopeptides/therapeutic use
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Inferior Vena Cava Tumor Thrombus From Thyroid Cancer Detected by 68Ga-PSMA-617 PET/CT.
Autorzy :
Li H; From the Department of Nuclear Medicine, Peking University Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Haidian.
Liu Y; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Zang J; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Yang Z; From the Department of Nuclear Medicine, Peking University Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Haidian.
Lin Y; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Mar 01; Vol. 46 (3), pp. 264-265.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Oligopeptides*
Positron Emission Tomography Computed Tomography*
Edetic Acid/*analogs & derivatives
Thrombosis/*complications
Thrombosis/*diagnostic imaging
Vena Cava, Inferior/*diagnostic imaging
Humans ; Male ; Middle Aged ; Thyroid Neoplasms/complications ; Vena Cava, Inferior/pathology ; Vena Cava, Inferior/physiopathology
Czasopismo naukowe
Tytuł :
Diagnostic Accuracy of Ga-PSMA PET/CT for Initial Detection in Patients With Suspected Prostate Cancer: A Systematic Review and Meta-Analysis.
Autorzy :
Satapathy S; All authors: Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Singh H; All authors: Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Kumar R; All authors: Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Mittal BR; All authors: Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
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Źródło :
AJR. American journal of roentgenology [AJR Am J Roentgenol] 2021 Mar; Vol. 216 (3), pp. 599-607. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Oligopeptides*
Radiopharmaceuticals*
Edetic Acid/*analogs & derivatives
Positron Emission Tomography Computed Tomography/*methods
Prostatic Neoplasms/*diagnostic imaging
Adult ; Aged ; Aged, 80 and over ; False Negative Reactions ; False Positive Reactions ; Humans ; Likelihood Functions ; Male ; Middle Aged ; Prostatic Neoplasms/pathology ; Publication Bias ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Prostate cancer GTV delineation with biparametric MRI and Ga-PSMA-PET: comparison of expert contours and semi-automated methods.
Autorzy :
Hearn N; Department of Radiation Oncology, Sunshine Coast University Hospital, Birtinya, Australia.; ICON Cancer Centre, Maroochydore, Australia.; University of the Sunshine Coast, Sippy Downs, Australia.
Blazak J; Department of Medical Imaging, Sunshine Coast University Hospital, Birtinya, Australia.
Vivian P; Department of Medical Imaging, Sunshine Coast University Hospital, Birtinya, Australia.
Vignarajah D; Department of Radiation Oncology, Sunshine Coast University Hospital, Birtinya, Australia.; ICON Cancer Centre, Maroochydore, Australia.
Cahill K; Department of Radiation Oncology, Sunshine Coast University Hospital, Birtinya, Australia.
Atwell D; Department of Radiation Oncology, Sunshine Coast University Hospital, Birtinya, Australia.; ICON Cancer Centre, Maroochydore, Australia.; University of the Sunshine Coast, Sippy Downs, Australia.
Lagopoulos J; University of the Sunshine Coast, Sippy Downs, Australia.; Sunshine Coast Mind and Neuroscience - Thompson Institute, University of the Sunshine Coast, Birtinya, Australia.
Min M; Department of Radiation Oncology, Sunshine Coast University Hospital, Birtinya, Australia.; ICON Cancer Centre, Maroochydore, Australia.; University of the Sunshine Coast, Sippy Downs, Australia.
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Źródło :
The British journal of radiology [Br J Radiol] 2021 Mar 01; Vol. 94 (1119), pp. 20201174. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Oligopeptides*
Radiopharmaceuticals*
Edetic Acid/*analogs & derivatives
Image Interpretation, Computer-Assisted/*methods
Magnetic Resonance Imaging/*methods
Positron-Emission Tomography/*methods
Prostatic Neoplasms/*diagnostic imaging
Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Observer Variation ; Prostate/diagnostic imaging ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Development and characterisation of novel, enzymatically stable oxytocin analogues with beneficial antidiabetic effects in high fat fed mice.
Autorzy :
Mohan S; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK.
McCloskey AG; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK.
McKillop AM; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK.
Flatt PR; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK.
Irwin N; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK. Electronic address: .
Moffett RC; Diabetes Research Group, Ulster University, Coleraine, Northern Ireland, UK.
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Mar; Vol. 1865 (3), pp. 129811. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Hypoglycemic Agents/*pharmacology
Islets of Langerhans/*drug effects
Obesity/*drug therapy
Oligopeptides/*pharmacology
Oxytocin/*pharmacology
Animals ; Blood Glucose/metabolism ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/pathology ; Diet, High-Fat/adverse effects ; Energy Intake/drug effects ; Energy Intake/genetics ; Female ; Glucagon/blood ; Half-Life ; Hypoglycemic Agents/chemical synthesis ; Insulin/metabolism ; Insulin Resistance ; Insulin Secretion/drug effects ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Male ; Mice ; Obesity/blood ; Obesity/etiology ; Obesity/pathology ; Oligopeptides/chemical synthesis ; Oxytocin/analogs & derivatives ; Oxytocin/chemical synthesis ; Protein Stability ; Triglycerides/blood
Czasopismo naukowe

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