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Wyszukujesz frazę ""Oliver, PL"" wg kryterium: Autor


Wyświetlanie 1-16 z 16
Tytuł:
Behavioural Characterisation of Macrod1 and Macrod2 Knockout Mice.
Autorzy:
Crawford K; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Oliver PL; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK.; MRC Harwell Institute, Harwell Campus, Didcot OX11 0RD, UK.
Agnew T; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Hunn BHM; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
Ahel I; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
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Źródło:
Cells [Cells] 2021 Feb 10; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Behavior, Animal*
Carboxylic Ester Hydrolases/*deficiency
DNA Repair Enzymes/*deficiency
Hydrolases/*deficiency
Animals ; Body Weight ; Carboxylic Ester Hydrolases/metabolism ; DNA Repair Enzymes/metabolism ; Female ; Gait ; Gene Knockout Techniques ; Genotype ; Hydrolases/metabolism ; Male ; Mice, Knockout ; Motor Activity ; Reproducibility of Results ; Mice
Czasopismo naukowe
Tytuł:
TLDc proteins: new players in the oxidative stress response and neurological disease.
Autorzy:
Finelli MJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.
Oliver PL; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK. peter.oliver@dpag.ox.ac.uk.
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2017 Oct; Vol. 28 (9-10), pp. 395-406. Date of Electronic Publication: 2017 Jul 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases/*genetics
Oxidative Stress/*genetics
Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Drug Discovery ; GTPase-Activating Proteins ; Humans ; Membrane Proteins ; Mitochondrial Proteins ; Nerve Tissue Proteins ; Neurodegenerative Diseases/physiopathology ; Nuclear Receptor Coactivators/genetics ; Nuclear Receptor Coactivators/metabolism ; Protein Domains ; Proteins/genetics ; Proteins/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy.
Autorzy:
Wobst HJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Denk F; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Oliver PL; MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Livieratos A; MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Taylor TN; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Knudsen MH; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Bengoa-Vergniory N; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Bannerman D; Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom.
Wade-Martins R; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Parkinson's Disease Centre, University of Oxford, Oxford, United Kingdom.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 24; Vol. 7, pp. 43198. Date of Electronic Publication: 2017 Feb 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tauopathies/*pathology
tau Proteins/*analysis
tau Proteins/*genetics
Animals ; Animals, Genetically Modified ; Behavior, Animal ; Disease Models, Animal ; Gene Expression ; Mice ; Mutant Proteins/analysis ; Mutant Proteins/genetics ; Protein Isoforms/analysis ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł:
Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
Autorzy:
Tan JY
Vance KW
Varela MA
Sirey T
Watson LM
Curtis HJ
Marinello M
Alves S
Steinkraus BR
Cooper S
Nesterova T
Brockdorff N
Fulga TA
Brice A
Sittler A
Oliver PL
Wood MJ
Ponting CP
Marques AC
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Źródło:
Nature structural & molecular biology [Nat Struct Mol Biol] 2015 Mar; Vol. 22 (3), pp. 272.
Typ publikacji:
Published Erratum
Tytuł:
Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
Autorzy:
Tan JY; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Vance KW; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Varela MA; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Sirey T; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Watson LM; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.; University of Cape Town, Division of Human Genetics, Cape Town, South Africa.
Curtis HJ; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Marinello M; Centre de Recherche de l'Institut du Cerveau et de la Moëlle épinière, Hôpital de la Pitié-Salpêtrière, Paris, France.; Université Pierre et Marie Curie-Paris 6, Paris, France.; Inserm, U 975, Paris, France.; CNRS, UMR 7225, Paris, France.; Département de Génétique et Cytogénétique, APHP, GH Pitié-Salpêtrière, Paris, France.
Alves S; Centre de Recherche de l'Institut du Cerveau et de la Moëlle épinière, Hôpital de la Pitié-Salpêtrière, Paris, France.; Université Pierre et Marie Curie-Paris 6, Paris, France.; Inserm, U 975, Paris, France.; CNRS, UMR 7225, Paris, France.; Département de Génétique et Cytogénétique, APHP, GH Pitié-Salpêtrière, Paris, France.
Steinkraus B; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Cooper S; University of Oxford, Department of Biochemistry, Oxford, United Kingdom.
Nesterova T; University of Oxford, Department of Biochemistry, Oxford, United Kingdom.
Brockdorff N; University of Oxford, Department of Biochemistry, Oxford, United Kingdom.
Fulga T; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Brice A; Centre de Recherche de l'Institut du Cerveau et de la Moëlle épinière, Hôpital de la Pitié-Salpêtrière, Paris, France.; Université Pierre et Marie Curie-Paris 6, Paris, France.; Inserm, U 975, Paris, France.; CNRS, UMR 7225, Paris, France.; Département de Génétique et Cytogénétique, APHP, GH Pitié-Salpêtrière, Paris, France.
Sittler A; Centre de Recherche de l'Institut du Cerveau et de la Moëlle épinière, Hôpital de la Pitié-Salpêtrière, Paris, France.; Université Pierre et Marie Curie-Paris 6, Paris, France.; Inserm, U 975, Paris, France.; CNRS, UMR 7225, Paris, France.
Oliver PL; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Wood MJ; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.; University of Cape Town, Division of Human Genetics, Cape Town, South Africa.
Ponting CP; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
Marques AC; MRC Functional Genomics Unit, University of Oxford, Oxford, UK.; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford, United Kingdom.
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Źródło:
Nature structural & molecular biology [Nat Struct Mol Biol] 2014 Nov; Vol. 21 (11), pp. 955-961. Date of Electronic Publication: 2014 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebellum/*metabolism
MicroRNAs/*genetics
Nerve Tissue Proteins/*genetics
RNA, Long Noncoding/*genetics
Retina/*metabolism
Spinocerebellar Ataxias/*genetics
Animals ; Ataxin-7 ; Cell Line, Tumor ; Cerebellum/pathology ; Feedback, Physiological ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Male ; Mice ; MicroRNAs/metabolism ; Mutation ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Neurons/pathology ; RNA, Long Noncoding/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Retina/pathology ; Signal Transduction ; Spinocerebellar Ataxias/metabolism ; Spinocerebellar Ataxias/pathology ; Transcription Initiation, Genetic
Czasopismo naukowe
Tytuł:
Laf4/Aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex.
Autorzy:
Moore JM; MRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
Oliver PL; MRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
Finelli MJ; MRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
Lee S; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Lickiss T; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Molnár Z; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Davies KE; MRC Functional Genomics Unit, University of Oxford, Oxford, United Kingdom.
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Źródło:
PloS one [PLoS One] 2014 Aug 27; Vol. 9 (8), pp. e105933. Date of Electronic Publication: 2014 Aug 27 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebral Cortex/*metabolism
GPI-Linked Proteins/*genetics
Neural Cell Adhesion Molecules/*genetics
Neurons/*metabolism
Nuclear Proteins/*genetics
Animals ; Animals, Newborn ; Cell Movement ; Cerebral Cortex/growth & development ; Cerebral Cortex/pathology ; Embryo, Mammalian ; GPI-Linked Proteins/metabolism ; Gene Expression Regulation, Developmental ; Humans ; Intellectual Disability/genetics ; Intellectual Disability/metabolism ; Intellectual Disability/pathology ; Mice ; Mice, Transgenic ; Microtomy ; Neural Cell Adhesion Molecules/metabolism ; Neurogenesis/genetics ; Neurons/pathology ; Nuclear Proteins/antagonists & inhibitors ; Nuclear Proteins/metabolism ; Protein Binding ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Tissue Culture Techniques ; Transcription Factors ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Oxr1 is essential for protection against oxidative stress-induced neurodegeneration.
Autorzy:
Oliver PL; Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom.
Finelli MJ
Edwards B
Bitoun E
Butts DL
Becker EB
Cheeseman MT
Davies B
Davies KE
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Źródło:
PLoS genetics [PLoS Genet] 2011 Oct; Vol. 7 (10), pp. e1002338. Date of Electronic Publication: 2011 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*
Cerebellum/*pathology
Neurodegenerative Diseases/*genetics
Neurons/*metabolism
Receptors, Neuropeptide/*metabolism
Animals ; Cerebellum/metabolism ; Cysteine/pharmacology ; Disease Models, Animal ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C3H ; Mice, Mutant Strains ; Neurons/pathology ; Orexin Receptors ; Receptors, Neuropeptide/genetics ; Sequence Deletion/genetics
Czasopismo naukowe
Tytuł:
Mouse genomic variation and its effect on phenotypes and gene regulation.
Autorzy:
Keane TM; The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1HH, UK.
Goodstadt L
Danecek P
White MA
Wong K
Yalcin B
Heger A
Agam A
Slater G
Goodson M
Furlotte NA
Eskin E
Nellåker C
Whitley H
Cleak J
Janowitz D
Hernandez-Pliego P
Edwards A
Belgard TG
Oliver PL
McIntyre RE
Bhomra A
Nicod J
Gan X
Yuan W
van der Weyden L
Steward CA
Bala S
Stalker J
Mott R
Durbin R
Jackson IJ
Czechanski A
Guerra-Assunção JA
Donahue LR
Reinholdt LG
Payseur BA
Ponting CP
Birney E
Flint J
Adams DJ
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Źródło:
Nature [Nature] 2011 Sep 14; Vol. 477 (7364), pp. 289-94. Date of Electronic Publication: 2011 Sep 14.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Phenotype*
Gene Expression Regulation/*genetics
Genetic Variation/*genetics
Genome/*genetics
Mice/*genetics
Mice, Inbred Strains/*genetics
Alleles ; Animals ; Animals, Laboratory/genetics ; Genomics ; Mice/classification ; Mice, Inbred C57BL/genetics ; Phylogeny ; Quantitative Trait Loci/genetics
Czasopismo naukowe
Tytuł:
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.
Autorzy:
Vernes SC; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Oliver PL
Spiteri E
Lockstone HE
Puliyadi R
Taylor JM
Ho J
Mombereau C
Brewer A
Lowy E
Nicod J
Groszer M
Baban D
Sahgal N
Cazier JB
Ragoussis J
Davies KE
Geschwind DH
Fisher SE
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Źródło:
PLoS genetics [PLoS Genet] 2011 Jul; Vol. 7 (7), pp. e1002145. Date of Electronic Publication: 2011 Jul 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Regulatory Networks*
Brain/*embryology
Forkhead Transcription Factors/*genetics
Neurites/*metabolism
Repressor Proteins/*genetics
Animals ; Cell Line, Tumor ; Chromatin Immunoprecipitation ; Corpus Striatum/growth & development ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Mutation ; Oligonucleotide Array Sequence Analysis/methods ; Primary Cell Culture ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa.
Autorzy:
Oliver PL; Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Goodstadt L
Bayes JJ
Birtle Z
Roach KC
Phadnis N
Beatson SA
Lunter G
Malik HS
Ponting CP
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Źródło:
PLoS genetics [PLoS Genet] 2009 Dec; Vol. 5 (12), pp. e1000753. Date of Electronic Publication: 2009 Dec 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Evolution, Molecular*
Genetic Speciation*
Histone-Lysine N-Methyltransferase/*genetics
Amino Acid Sequence ; Animals ; Base Sequence ; DNA, Satellite/genetics ; Histone-Lysine N-Methyltransferase/chemistry ; Humans ; Models, Biological ; Molecular Sequence Data ; Phylogeny ; Primates/genetics ; Rodentia/genetics ; Selection, Genetic ; Zinc Fingers/genetics
Czasopismo naukowe
Tytuł:
Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain.
Autorzy:
Ponjavic J; MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Oliver PL
Lunter G
Ponting CP
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Źródło:
PLoS genetics [PLoS Genet] 2009 Aug; Vol. 5 (8), pp. e1000617. Date of Electronic Publication: 2009 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genomics*
Brain/*growth & development
Brain/*metabolism
RNA, Messenger/*metabolism
RNA, Untranslated/*metabolism
Animals ; Biological Transport ; Gene Expression Regulation, Developmental ; Mice ; Open Reading Frames ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; RNA, Untranslated/chemistry ; RNA, Untranslated/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease.
Autorzy:
Oliver PL; Department of Physiology, Anatomy and Genetics, MRC Functional Genetics Unit, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK.
Bitoun E
Davies KE
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2007 Jul; Vol. 18 (6-7), pp. 412-24. Date of Electronic Publication: 2007 May 21.
Typ publikacji:
Comparative Study; Journal Article; Review
MeSH Terms:
Genetic Diseases, Inborn/*genetics
Mice, Transgenic/*genetics
Animals ; Genotype ; Humans ; Mice ; Mutant Proteins/genetics ; Phenotype
Czasopismo naukowe
Tytuł:
Transcription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene.
Autorzy:
Scharf S; Institute of Pharmaceutical Biology/ZAFES, Biocenter, JWG-University of Frankfurt, Frankfurt/Main, Germany.
Zech J
Bursen A
Schraets D
Oliver PL
Kliem S
Pfitzner E
Gillert E
Dingermann T
Marschalek R
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Źródło:
Oncogene [Oncogene] 2007 Mar 01; Vol. 26 (10), pp. 1361-71. Date of Electronic Publication: 2006 Sep 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Promoter Regions, Genetic*
Recombination, Genetic*
Transcription, Genetic*
Myeloid-Lymphoid Leukemia Protein/*genetics
Animals ; Chromatin ; Etoposide ; Histone-Lysine N-Methyltransferase ; Humans ; Mice ; RNA Polymerase II
Czasopismo naukowe
    Wyświetlanie 1-16 z 16

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